Submit
Enter a list of mammalian genes or proteins in Entrez gene symbol format to receive results of a protein-protein interactions (PPI) subnetwork that connects the enriched genes/proteins with known protein-protein interactions using Genes2Networks (G2N). G2N connects input list of genes/proteins using the shortest path algorithms using known PPI from the selected databases.
API
Command line version
From here (JAR format, 3.6
MB) you can download a command line standalone version of G2N.
General format on how to run the G2N command line tool:
java -jar [G2N JAR file] [input gene list] [output SIG file] [backgroundSigFile1, backgroundSigFile2, ...]
Example of how to run the G2N command line tool:
java -jar G2N-1.5-SNAPSHOT-jar-with-dependencies.jar genelist.txt results.sig huMAP.sig Biocarta.sig
Download datasets
| Database | Download | Type | Interactions | Interactors | PMID |
|---|---|---|---|---|---|
| BIND | Literature PPI | 25622 | 5528 |  |
|
| Biocarta | Literature PPI | 756 | 352 | |
|
| BioGRID | Mixed | 68759 | 7312 | |
|
| BioPLEX | Mass-spec | 56553 | 8610 | |
|
| DIP | Literature PPI | 3822 | 1946 | |
|
| figeys | Mass-spec | 6452 | 2033 | |
|
| HPRD | Literature PPI | 47496 | 7490 | |
|
| huMAP | Mass-spec | 62214 | 6061 | |
|
| InnateDB | Literature PPI | 4576 | 1523 | |
|
| IntAct | Mixed | 15726 | 4186 | |
|
| iREF | Mixed | 28417 | 5403 | |
|
| KEGG | Literature PPI | 13993 | 1198 | |
|
| MINT | Literature PPI | 75065 | 9415 | |
|
| MiPS | Mass-spec | 606 | 373 | |
|
| PDZbase | Literature PPI | 244 | 159 | |
|
| PPID | Literature PPI | 6998 | 1208 | |
|
| Sets2Networks | Predicted | 3000 | 828 | |
|
| SNAVI | Literature PPI | 2007 | 442 | |
|
| Stelzl | Mass-spec | 6207 | 1702 | |
|
| Vidal | Yeast-2-Hybrid | 6726 | 2541 | |