association	dataset	threshold value	standardized value
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_9527_KO_P2ry1_SRP342865	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.54783
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.658
BICR10	DepMap CRISPR Gene Dependency	1.0	2.34135
GLI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02269
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90779
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5472759-ncomms15770-s2.xlsx-KIRC_mean_chr8_GISTIC_CN_by_gen-Supplementary_Data_1_TCGA_KIRC_mean_CN_near_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
esophagus	HPA Tissue Gene Expression Profiles	1.0	1.14922
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7053-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OCUBM	DepMap CRISPR Gene Dependency	1.0	3.66631
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21537
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02642
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19809
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.33052
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064203
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227946
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898252
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271043
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KOSC2	DepMap CRISPR Gene Dependency	1.0	2.07768
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36074
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37359
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52564
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08127
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13309
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4593
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
19838208-TableS1	GeneSigDB Published Gene Signatures	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.023898
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43456
EFM-192A	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73001
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625269
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08177
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992313
XC-81-LR46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.620372
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889994
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HGC27	DepMap CRISPR Gene Dependency	1.0	2.95821
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30453
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10416
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81273
KP4	CCLE Cell Line Gene CNV Profiles	1.0	1.46242
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855231
Perturb_5387_KO_Isl1_SRP380182	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.74693
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32192
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31219
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0726-SM-47JXI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66107
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888684
AC-36-SY22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217964
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3841
hsa-miR-4768-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
Perturb_17574_KO_Airn_SRP157112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.60281
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.642
BC-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21973
Perturb_1393_KO_Rad9_SRP214104	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.45363
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0003
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14821
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45918
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_5010_KO_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BE-27-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228188
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66098
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_322_KD_USP39_SRP279798	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39158
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27631
hsa-miR-4534	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2754
PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01032
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2995
ZR-75-30	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
CHD7	ENCODE Transcription Factor Targets	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225274
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59065
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.678
GSE158853_0_v_1_hmgcs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222037
periventricular stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41608
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.57407
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.60574
GTEX-XQ8I-1626-SM-4BOOI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26383
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21908
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77Q-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38817
DF-00-BX35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214272
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65859
GSE206870,GSE206872_4_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUJ4-1126-SM-4BOPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1295
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4
RECQL	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
Crohn Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210476_9_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.925597
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2188
GTEX-XUZC-0326-SM-4BOO8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965314
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.556385
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01224
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-1226-SM-4DXT6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58999
SSBP1	Pathway Commons Protein-Protein Interactions	1.0	null
NB6	DepMap CRISPR Gene Dependency	1.0	2.38196
PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D9_vs_D15-Unnamed_4_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_CAMTA1_vs_subEV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16131
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.9489
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881971
HNRNPDL	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76284
Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.01966
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42854
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10014
RFC2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7591516-41467_2020_18955_MOESM6_ESM.xlsx-Overlap_DEGs_MSC_Diff_GCTB-Gene_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08213
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.3651
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7359
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsomedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20196
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74768
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825847
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975769
Perturb_1814_KO_N4bp1_SRP255180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.59967
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06918
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24901
Sarcoma_SARC_TCGA-K1-A3PO-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110644
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22477
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270118
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.20203
Prostate adenocarcinoma_PRAD_TCGA-EJ-5519-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4733
NB69	DepMap CRISPR Gene Dependency	1.0	3.98769
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2615_Mut_SF3B1_SRP249914	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.63227
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inhibin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_767_mouse_Skin - 1 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-3074-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CDCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50633
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927212
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6815
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.96194
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2351
periventricular stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02482
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06146
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205265
GCNP_SHH_UP_LATE.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15584
Inflammation	CTD Gene-Disease Associations	1.0	1.70988
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27675
Lung adenocarcinoma_LUAD_TCGA-55-6979-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942934
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14686_KO_Sirt3_SRP277814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.42649
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25779
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02344
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
GSE111035,GSE111040_3_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS-578-T	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2984
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43081
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42204
HCC366	DepMap CRISPR Gene Dependency	1.0	2.09296
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0726-SM-3NM9A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15939
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CGGBP1	Pathway Commons Protein-Protein Interactions	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278601
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33249
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00815
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0426-SM-4BRVW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96946
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4303
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942934
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14085
RB1_KD_GSE50532_592_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15107
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-1126-SM-48TCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8034
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06283
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356962
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRPD2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6211
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865023
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
GTEX-Q2AH-1026-SM-48TZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80002
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MG-63	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Chloroplast thylakoid membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.458
Mesonephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76494
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26451
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044602
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.039116
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MESOV	DepMap CRISPR Gene Dependency	1.0	4.07972
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1323	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167218_1_v_0_hoxd12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MXI1	ENCODE Transcription Factor Targets	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01741
hsa-miR-4717-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28749
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.25266
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1505
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71716
MM253	DepMap CRISPR Gene Dependency	1.0	3.51902
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96645
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30063
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_8_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52706
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833884
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81432
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.142142
SRSF2	Pathway Commons Protein-Protein Interactions	1.0	null
KP2	DepMap CRISPR Gene Dependency	1.0	2.43492
lung	HPA Tissue Gene Expression Profiles	1.0	1.03383
GTEX-PLZ5-0826-SM-3P5ZW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26092
MLL3/4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
GTEX-TKQ1-0526-SM-4DXTG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18145
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.917544
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CMSS1	Pathway Commons Protein-Protein Interactions	1.0	null
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15855
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986148
hsa-miR-218	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00356
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04759
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06258
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02082
SOX17	ChEA Transcription Factor Targets	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06146
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.942462
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14129
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.452803
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39425
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01741
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06146
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364885
HOUAI	DepMap CRISPR Gene Dependency	1.0	3.59864
nucleus subcoeruleus, r1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32277
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HGC-27	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
Weight Loss	CTD Gene-Disease Associations	1.0	1.14438
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4383
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0504	DepMap CRISPR Gene Dependency	1.0	2.29163
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390891
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9072
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-0626-SM-4KL1S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16285
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09189
AIRE_KO_GDS2274_246_mouse_Medullary thymic epithelial cells (with high CD80 expression)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8732
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906756
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03679
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27184
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57365
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6925
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327165
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
VCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39724
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.850742
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13136
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03193
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	2.30491
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07962
RSL1D1	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01828
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08271
adrenalgland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01404
fat_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
Perturb_13304_KO_Tet2_SRP338315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.58806
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27902
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65259
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848816
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234302
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39047
Bipolar Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
SCLC22H	DepMap CRISPR Gene Dependency	1.0	4.56847
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.95209
hsa-miR-381	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06152
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.86373
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76678
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.4502
MAX	ENCODE Transcription Factor Targets	1.0	null
CAL-72	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUCO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82469
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25116
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37994
GTEX-WFON-0926-SM-4LVMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56737
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
A_CA_04_2009_4dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.21988
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.8071
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20289
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	0.899208
NOL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50559
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09953
Perturb_17528_KD_MEOX1_SRP213607	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.96587
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-W5WG-1526-SM-4LMIG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05694
GTEX-T5JW-1426-SM-4DM5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17559
EFM192A	CCLE Cell Line Gene CNV Profiles	1.0	2.15983
Coronary Artery Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	1.41948
TFAM	Pathway Commons Protein-Protein Interactions	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.6553
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNRPA1	Pathway Commons Protein-Protein Interactions	1.0	null
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36932
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GA-04-JM33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202621
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7501-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12171_Mut_TP53_SRP287851	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.37833
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17997
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06097
PPARalpha_OE_GDS2289_244_mouse_Skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
WNT_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97887
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204016
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6171
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1644
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41021
hsa-miR-548e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95337
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00589
LYZ	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057907
hsa-miR-4294	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Perturb_5260_KD_Ubn2_SRP323703	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06595
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organ development	GO Biological Process Annotations 2015	1.0	null
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01366
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE510	CCLE Cell Line Gene CNV Profiles	1.0	2.03944
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.64963
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990057
Perturb_12140_KD_PRPF8_SRP093921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.895
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53524
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214399
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96517
RALY	Pathway Commons Protein-Protein Interactions	1.0	null
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1264
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE84462,GSE84762_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IGF2BP3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUJ4-2126-SM-4BOOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30872
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.3206
Chloroplast thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.405
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208106
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77029
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09963
AD-06-OB47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213469
MG63	CCLE Cell Line Gene CNV Profiles	1.0	2.84814
HUCCT1	DepMap CRISPR Gene Dependency	1.0	2.0796
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18131
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12668
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35393
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21139
GTEX-TML8-1226-SM-32QON	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914068
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51271
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20387
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.88
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905718
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15567
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01331
inner SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908968
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4111
MMS22L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25164
Perturb_5700_KO_Airn_SRP157112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.60281
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04759
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.888738
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6053
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85053
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.44
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.09366
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46048
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02627
496100570_HIP_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7724
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45267
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35715
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4424
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.509659
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.97338
HC-18-NB46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259841
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100648_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22145
NACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47383
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16232
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5233_OE_Dppa2_SRP218369	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.57919
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08515
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_20_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3321
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61031
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55482
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3375
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040493
OCILY19	DepMap CRISPR Gene Dependency	1.0	3.46524
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14204
Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166004_3_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6039
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.963
PAX5	ENCODE Transcription Factor Targets	1.0	null
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.483757
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9395
BL7472 (ADRM1)	NURSA Protein Complexes	1.0	null
Ovarian surface epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lung cancer	GWASdb SNP-Disease Associations	1.0	0.567793
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.57407
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05954
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06263
Bipotential generated pre-granulosa(BPG) cell_Fetal ovary_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RASGRF1_KD_GDS2816_287_human_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29497
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309384
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2169
GB-73-QS80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280019
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
lateral wings of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24884
Ezh2_KO_GDS3765_515_mouse_Primary preadipocyte cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BL2296 (EDC4)	NURSA Protein Complexes	1.0	null
Methionine	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_4504_KO_Hoxa1_SRP174196	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.5723
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	1.34327
RFC3	Pathway Commons Protein-Protein Interactions	1.0	null
ACBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23019
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126127_2_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBMX	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10996
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233135
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2642
GTEX-WEY5-1526-SM-4LMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847782
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.496428
Perturb_13807_KD_Qki_SRP116547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.592
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4952
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898252
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.70326
GTEX-XUW1-1526-SM-4BOOY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44273
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890895
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.868
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0626
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214487
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4097
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2346
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF354A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3417
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JHUEM3	CCLE Cell Line Gene CNV Profiles	1.0	1.37396
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERBB2_druginhibition_8_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.56076
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20731
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07367
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49215
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.989263
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890252
hsa-miR-4723-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1035
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4417	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.190786
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21458
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.72092
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06871
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29715
MYBL2	ChEA Transcription Factor Targets	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50076
hsa-miR-4794	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.678086
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36283
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3EP-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Photosystem II oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.482
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
15642130-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67021
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210373_0_v_1_cntnap4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27902
GTEX-QCQG-0726-SM-48U1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25537
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66834
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97699
H3K36me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parahippocampal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85102
CIRBP	Pathway Commons Protein-Protein Interactions	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.497007
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055136
mRNA_KLF4_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233162
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZN-1826-SM-4DXUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82547
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393684
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134029_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58664
GSE213228_1_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66098
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Preputial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7399-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38547
CHD2	ENCODE Transcription Factor Targets	1.0	null
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66941
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
r4 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02398
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1944	DepMap CRISPR Gene Dependency	1.0	2.56534
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52858
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232098
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16246
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.74055
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09187
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
CDC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15163
20140255-TableS2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-1526-SM-4AT4K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999457
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04975
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309406
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26255
extrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159838
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93457
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.774448
Chloroplast thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.381
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17915
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.452538
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1492
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13374
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5946
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44358
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKM1	CCLE Cell Line Gene CNV Profiles	1.0	1.33739
Lung adenocarcinoma_LUAD_TCGA-44-8120-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150215_1_v_0_etl4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.571478
hsa-miR-766	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
HIST1H1C	Pathway Commons Protein-Protein Interactions	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.872911
Germinal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10899
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17531
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5823
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.20816
mRNA_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_4600_KO_Mettl3_SRP048598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
mRNA_ESRRB_19136965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XAJ8-0326-SM-47JYI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6265
GTEX-REY6-1426-SM-48FDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973344
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1522
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPRD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5184
hsa-miR-558	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4659
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_4_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044759
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47655
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28355
hsa-miR-4676-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XV7Q-1026-SM-4BRVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01087
RFC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
hsa-miR-1273f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-PLZ6-0626-SM-3P61B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0444
CDH4-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55355
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47956
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_13851_KO_RET_ERP126468	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82037
ASH2L	ChEA Transcription Factor Targets	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1866
TWSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00249
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18961
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.367771
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49269
Plastid thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.403
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HD-MY-Z	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313795
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70038
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17554
RAD21	ENCODE Transcription Factor Targets	1.0	null
NCIH358	DepMap CRISPR Gene Dependency	1.0	2.44367
GSE158285_0_v_1_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17585
GTEX-T5JC-1926-SM-4DM6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01295
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920632
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49068
Anterior amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00162
hsa-miR-4704-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-1229	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Osteogenesis imperfecta type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.540388
E2F4	ENCODE Transcription Factor Targets	1.0	null
PMC8992440__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922414
subthalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17546
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65342
GTEX-Q2AG-0326-SM-48U1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07215
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7785
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10189
SAOS-2	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10425
GTEX-QDVN-1126-SM-48TZ7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983855
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36182
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11919
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.564172
DE-34-DT75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232888
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49485
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943023
GTEX-WFJO-1126-SM-4LVLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50604
GTEX-S4Z8-0726-SM-4GICB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61903
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1954	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
GSE131425_2_v_0_arg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OC-10-FB51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215979
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SE5C-1026-SM-4BRUG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854524
TGBC18TKB	DepMap CRISPR Gene Dependency	1.0	2.27159
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00332
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49177
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847323
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.65086
GTEX-T8EM-0626-SM-4DM62	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48301
496100285_TCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12085
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-296-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72611
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55315
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FDXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2294
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64994
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054426
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7624
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RASL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07532
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.961786
GTEX-PWCY-0826-SM-48TCR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48055
bed nucleus of the stria terminalis, mediocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60145
GTEX-RU1J-0426-SM-46MUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4482
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22873
GTEX-OXRK-1426-SM-3NB19	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997643
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8474-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35793
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14387_KD_MECOM_SRP276625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.65257
POLR3A	Pathway Commons Protein-Protein Interactions	1.0	null
JJN-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tcof1_15522210_neuroblastoma_lof_mouse_gpl339_gds998	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.04487
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052446
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2924
HCC2935	DepMap CRISPR Gene Dependency	1.0	6.09895
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
RFC4	Pathway Commons Protein-Protein Interactions	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4781
Hypertension	HuGE Navigator Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03643
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36418
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39134
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XXEK-0526-SM-4BRWD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21853
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24901
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-1026-SM-4AD4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6014
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4691
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50189
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Type 2 diabetes mellitus_Hepatic Tissue_GSE2899	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.37435
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Set3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.252
CAL120	DepMap CRISPR Gene Dependency	1.0	2.46868
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9032
GTEX-P4PQ-0726-SM-3NMCR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.73865
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57289
GTEX-RUSQ-0926-SM-47JWU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989278
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8878
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15501
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.1529
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31697
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.858635
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
not applicable_asthma_GSE43696_369_mouse_bronchial epithelial cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Anorexia	CTD Gene-Disease Associations	1.0	1.02708
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833884
RPA3	Pathway Commons Protein-Protein Interactions	1.0	null
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64058
Medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18798
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19407
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35951
DDX21	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10518
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PANC-08-13	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224567
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27333
Lung Diseases	CTD Gene-Disease Associations	1.0	1.06952
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_12_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4772-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBMS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNAJC9	Pathway Commons Protein-Protein Interactions	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08813
PMC6529937-Table_1.xlsx-IRF1_dependent_upregulated-gene_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Barr body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5044
RPA1	Pathway Commons Protein-Protein Interactions	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JI-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
EE-85-SK26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247971
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	1.9623
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10045
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43227
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058712
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-1326-SM-4BRWW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38308
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1088_KO_Perk_SRP370072	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.45431
Prostate adenocarcinoma_PRAD_TCGA-VP-A87J-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.361659
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49676
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40407
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37265
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50477
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8915
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23309
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1605
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mifepristone_mus musculus_gpl6887_gse39270	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVCAR-8	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KYSE-510	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832159
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4877
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EVSAT	DepMap CRISPR Gene Dependency	1.0	2.02867
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0024
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.045006
MPG	Pathway Commons Protein-Protein Interactions	1.0	null
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.248464
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24757
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31932
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21212
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21102
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06831
EBC1	DepMap CRISPR Gene Dependency	1.0	3.23783
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.848422
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58825
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23191
EZH2	ENCODE Transcription Factor Targets	1.0	null
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53195
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898252
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.26451
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.57407
Perturb_5108_KO_Dax1_SRP309688	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.4996
Perturb_14661_KO_Insm1|Pax6_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28899
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7081
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354455
WC-67-DI84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311639
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50433
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4624
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18334
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19493
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0726-SM-3LK5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47742
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949403
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050247
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4849
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21006
A_CA_04_2009_4dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69316
ADNP-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
arthritis, rheumatoid; coronary artery disease; crohn disease; crohn's disease; diabetes mellitus type ii; diabetes mellitus, insulin-dependent; diabetes mellitus, type 1; diabetes mellitus, type 2; hypertension; rheumatoid arthritis	GAD Gene-Disease Associations	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30422
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.702428
GSE221577_4_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6958
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin-epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0996306
SNU1327	DepMap CRISPR Gene Dependency	1.0	3.56278
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4661-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.02264
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05203
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51208
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270158
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03714
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
Subcortical maternal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2006
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371857
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10055
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02542
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06318
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24371
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10008
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.43673
GTEX-T5JC-1826-SM-4DM6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848596
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250326
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863474
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPS10	Pathway Commons Protein-Protein Interactions	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831108
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01296
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57963
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959936
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69022
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75552
UNC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16552
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02352
hsa-miR-4742-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917712
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-AAQO-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349901
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05255
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40869
CB-02-XL81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354194
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR0B1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-4699-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00066
SALL4-18804426-XEN-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pyloric stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67732
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
Fetal Death	CTD Gene-Disease Associations	1.0	1.26329
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213833
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.83954
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04244
bladder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053286
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11545
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49025
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.89922
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.2633
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
IREB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07057
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070241
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07501
middle temporal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922734
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.25415
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17091
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30719
RBBP5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-88-WQ63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256048
Ovarian surface epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
Congenital adrenal insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-0926-SM-48TCE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22872
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29141
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.913072
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225246
esophagus	GTEx Tissue Gene Expression Profiles	1.0	1.00782
Plastid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D4_vs_D9-Unnamed_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979777
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2474
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883307
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73487
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1256	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25864
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.02522
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62383
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07975
myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.472704
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATM_knockout_75_GSE23116	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.22567
icSARS-Cov_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.86501
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01631
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39611
Perturb_14972_KO_Max_SRP225905	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897534
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220696
pou5f1_16518401_mesc_lof_mouse_gpl1261_gds1824	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-2.32245
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55841
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39089
inferior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05575
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.46
RPL22	Pathway Commons Protein-Protein Interactions	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5306
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.4176
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S3XE-0826-SM-4AD4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53804
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59478
CTCF	ENCODE Transcription Factor Targets	1.0	null
upper dorsal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03713
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25697
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58994
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33565
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08086
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15239_KD_ERCC6L2_SRP349996	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.13038
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42649
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YT-0726-SM-3MJHA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28853
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8428
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4409
RPS3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29637
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19322
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231891_5_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56485
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03993
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854694
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2006
MYOG	ENCODE Transcription Factor Targets	1.0	null
vestibular nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05519
single-organism process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3682-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.375
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
acute myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.482084
Perturb_9515_KO_Sall4_ERP111723	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.8861
hsa-miR-27a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arthritis, Rheumatoid	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3233
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18118
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73888
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43903
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.07391
H1FX	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.4332
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261785
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.11181
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29715
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18452
TBP	ENCODE Transcription Factor Targets	1.0	null
Perturb_4788_OE_Gadd45g_SRP315685	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.188
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30174
Hermansky-Pudlak syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
t63-testes_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.03538
TP63	ChEA Transcription Factor Targets	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM14	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-1326-SM-48TYY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856446
Perturb_6688_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.45483
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.06442
hsa-miR-4704-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-WFG8-1126-SM-4LVN1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948439
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17841
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38678
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4742
Perturb_2840_OE_GIT2_SRP357777	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Venous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28052
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
HCC1419	CCLE Cell Line Gene CNV Profiles	1.0	2.08632
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56462
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33175
Perturb_17325_KO_Dis3l2_SRP322105	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.3588
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
M059K	CCLE Cell Line Gene CNV Profiles	-1.0	-1.353
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-05-GR23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253165
Ventral tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24523
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78171
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78597
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.86504
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833884
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5501-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97826
heart_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
diagonal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11111
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922414
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22057
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6584
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97639
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22691
KIF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4769
Perturb_5343_KO_Taf3_SRP007832	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
KDM4A	ENCODE Transcription Factor Targets	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.697034
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14312
GSE92364_1_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS24	Pathway Commons Protein-Protein Interactions	1.0	null
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06779
hsa-miR-2113	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ETS2_KD_GSE62168_258_mouse_mouse trophoblast stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
paracentral lobule, anterior part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84838
GTEX-X15G-1626-SM-3NMB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980597
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISTMES2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80259
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460638
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15849
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61535
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.18863
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58665
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16507
Perturb_11192_KO_Fak_SRP279401	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32756
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of Dg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11072
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01559
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.431772
NCIH2171	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67343
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.03009
GTEX-XPVG-1526-SM-4B66C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18614
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79329
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202556
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877236
PRICKLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05638
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75791
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8517
SSB	Pathway Commons Protein-Protein Interactions	1.0	null
PMVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42172
GSE114992,GSE114993_4_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5835
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.642
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.711
superficial stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03551
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040575
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65364
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4396
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.846432
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_8_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66015
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73539
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03193
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-2726-SM-4LMIC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02421
nucleus of Barrington	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84995
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE-75-WF43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204174
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68174
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
HO-1-U-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
GTEX-P4PP-0726-SM-3NM9S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42974
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222162
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
pg4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Down_REST	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q734-1426-SM-48TZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901742
PLPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09717
MTF2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE200099_2_v_0_honokiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.73186
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23273
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03772
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26808
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16968
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93816
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-1226-SM-4DXT7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997905
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5471
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07028
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR1C	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471687
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272701
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1015
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	DepMap CRISPR Gene Dependency	1.0	2.47261
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.913336
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05905
hsa-miR-4272	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361641
GTEX-S4Z8-1226-SM-4AD6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22512
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4296	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16042
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7793
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HNRNPCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8028
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983114
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.871098
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297029
GTEX-UJHI-0926-SM-4IHKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12379
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08609
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04675
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986148
Perturb_5136_KD_Dax1_SRP311833	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.7999
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0626-SM-3P61E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26988
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2137
RPS25	Pathway Commons Protein-Protein Interactions	1.0	null
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15686
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04276
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31253
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860799
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9451
Thylakoid light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.511
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.127648
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27814
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2186
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.638514
biological_process	GO Biological Process Annotations 2015	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69995
cancer	GWASdb SNP-Disease Associations	1.0	0.037466
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55G-1126-SM-48FDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02989
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235852
amygdaloid complex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05556
Brain Lower Grade Glioma_LGG_TCGA-DB-5277-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14847
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64462
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329214
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.81502
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0175
PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_4523_KO_Dpf2_ERP105019	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.96088
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.853936
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49903
HOP62	DepMap CRISPR Gene Dependency	1.0	2.34805
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92675
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNBP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56347
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20374
hsa-miR-552	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17026
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02773
r6 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0847
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4766-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
OPM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69497
Infertility, Male	CTD Gene-Disease Associations	1.0	1.12014
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058759
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1241
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1954	DepMap CRISPR Gene Dependency	1.0	2.11861
hsa-miR-548f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BD-93-AM31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341028
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849245
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65544
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01125
LK2	DepMap CRISPR Gene Dependency	1.0	2.72404
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.98253
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5199
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58593
Perturb_5521_KD_Apoa4_SRP393880	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.53761
ITGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05528
Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7933
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55602
LDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38269
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MNDA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4PQ-1526-SM-3NMCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41084
Perturb_9516_Mut_Sall4_ERP111723	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.02609
UA-06-UV98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239407
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17026
RBM3	Pathway Commons Protein-Protein Interactions	1.0	null
PPARD_KO_GDS4320_619_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.946496
POU5F1	ChEA Transcription Factor Targets	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35311
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4538_KO_Mtf2_SRP103933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.78605
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03107
ALYREF	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Obstructive sleep apnea_Hepatic Tissue_GSE1873	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.20414
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23454
SLC36A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52012
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_14436_OE_Cyp17_SRP340317	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.12637
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7387
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.84055
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7952
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053371
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03453
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24277
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196199_0_v_1_zbtb20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64299
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56956
GSE182680,GSE182683_10_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.88206
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.993865
CDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57379
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.987875
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.918699
Human - Motor Cortex - Cluster - LAMP5+ AARD+ Layer 1-6 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06953
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30286
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045583
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7925-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-1026-SM-4LVML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8892
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01068
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78314
bladder	GTEx Tissue Gene Expression Profiles	1.0	0.99559
NCIH2081	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53359
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03858
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13481
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QS-01A-61R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74657
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23323
GTEX-T6MO-0626-SM-4DM6P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24964
PARP1	Pathway Commons Protein-Protein Interactions	1.0	null
estradiol_mus musculus_gpl81_gse1839	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-UJHI-1426-SM-3DB9C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961185
Perturb_17541_KD_MEOX1_SRP213607	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
THO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
SB-29-ZH97_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223226
hsa-miR-4311	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Bladder-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.412684
GTEX-S32W-1126-SM-4AD5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10237
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974825
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55W-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.4202
inferior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30488
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08881
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06683
HS695T	DepMap CRISPR Gene Dependency	1.0	3.14176
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2624
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
NB-75-RF23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26924
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3563_KD_HMGA1_SRP299065	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.45345
GTEX-TKQ1-0426-SM-4DXT4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60151
r5 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41698
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202118
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YBX1	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H1B	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63637
Legg-Calve-Perthes disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BHT101	DepMap CRISPR Gene Dependency	1.0	3.46385
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.999846
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897534
Plastid envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.916
YY1	ENCODE Transcription Factor Targets	1.0	null
KYSE510	DepMap CRISPR Gene Dependency	1.0	6.70855
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRAK4_Deficiency_GDS2641_653_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76464
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99978
CLIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00582
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-1326-SM-3NB1B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15776
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.846432
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25429
GTEX-RTLS-1226-SM-46MUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862988
GTEX-SNOS-0726-SM-4DM5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920349
Perturb_6689_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.38712
hsa-miR-4764-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7056-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417249
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60311
GSE184902_3_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230566
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262266
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79609
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168797_2_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03884
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EXOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70117
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7392
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	2.43866
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14839
hsa-miR-3183	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58665
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HMGB1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-1526-SM-3NB1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5466
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.975
HCC1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0935
cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04533
59M	CCLE Cell Line Gene CNV Profiles	1.0	1.36728
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septodiagonal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17622
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867207
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09848
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43532
GTEX-XUW1-1326-SM-4BOO1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36435
EWS502	DepMap CRISPR Gene Dependency	1.0	2.02673
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3235
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879457
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33511
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-NFK9-1226-SM-3LK79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68787
HMGB2	Pathway Commons Protein-Protein Interactions	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287092
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02999
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.785984
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51233
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80842
KD	DepMap CRISPR Gene Dependency	1.0	2.48858
Prostate adenocarcinoma_PRAD_TCGA-G9-6494-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63464
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90852
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-335	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-XBED-1726-SM-47JYO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87198
BV173	CCLE Cell Line Gene CNV Profiles	1.0	1.3621
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56155
cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066328
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AKT1_knockout_215_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.48827
GTEX-RU72-0626-SM-46MUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31525
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86771
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5019
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38008
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
nucleotide-excision repair factor 2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0386
CBX2	ENCODE Transcription Factor Targets	1.0	null
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.941573
Perturb_9526_KO_P2ry1_SRP342865	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8878
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32007
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
hsa-miR-4709-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25332
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.490619
PMC7591516-41467_2020_18955_MOESM6_ESM.xlsx-Overlap_DEGs_MSC_Diff_GCTB-Symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.31536
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Coagulating gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
periventricular stratum of Dg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60063
Perturb_2428_KD_FOXD4L6_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.66661
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240436
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMILIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22776
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835908
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4169
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09481
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-0626-SM-4DXTV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02571
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-431	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-S4Q7-0526-SM-4AD5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33442
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08328
hsa-miR-940	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568285
SERHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29794
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.76397
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16408
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12993
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833884
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
20940404-SuppTableb	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298795
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.1086
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14836
EWSR1	ChEA Transcription Factor Targets	1.0	null
USP10	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.86331
ELK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33555
RFC5	Pathway Commons Protein-Protein Interactions	1.0	null
SRSF5	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-300	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ANKRD33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84884
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04879
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5418
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40481
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30286
GTEX-WEY5-1026-SM-4LMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10996
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0331
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47493
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63973
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zygotene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.14504
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE195786_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AF-19-KN63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228951
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044313
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3401
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6856
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31725
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L33	DepMap CRISPR Gene Dependency	1.0	2.65275
MG63	DepMap CRISPR Gene Dependency	1.0	2.30885
Perturb_5160_KO_Mettl3_SRP048598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.91264
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10274
BD-85-AU55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23012
GTEX-PLZ6-0826-SM-3P61K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48848
GTEX-QDVJ-0826-SM-48U1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870604
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.30666
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08326
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130690,GSE130692_2_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39595
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69867
PG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90661
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-OIZG-0926-SM-3LK5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945107
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0153
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-73-QS80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208414
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2I	Pathway Commons Protein-Protein Interactions	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.33131
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_ZFP281_21915945	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.643387
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.662
Perturb_15240_KD_ERCC6L2_SRP349996	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.38326
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6721
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21081
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.75371
GTEX-V1D1-1126-SM-4JBHT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14427
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100607_TCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86941
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7616
GTEX-XBEW-1426-SM-4AT4J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948279
MYC	ChEA Transcription Factor Targets	1.0	null
CB-55-GX92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276484
CTBP2	ENCODE Transcription Factor Targets	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18954
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8967
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054678
Perturb_5064_KO_Trim66_SRP311833	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.86122
Hepatitis	CTD Gene-Disease Associations	1.0	1.01137
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.691
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24505
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08491
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.169
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53503
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7935
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02226
SOX10	JASPAR Predicted Transcription Factor Targets	1.0	null
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81326
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5750-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14715_KO_Tbx3_SRP305624	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.50218
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3537
RPRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01265
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2287
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6062
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-1026-SM-4AD5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00529
Giant cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.427
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR3F	Pathway Commons Protein-Protein Interactions	1.0	null
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1699
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896866
GSE196699_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00852
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8422
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32835
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-5095	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08533
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964051
GSE151364,GSE151366_1_v_2_taf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261235
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74349
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM16_DEPLETION_GDS4021_460_mouse_WAT - white adipose tissue (stromal-vascular cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_16621_KO_Zmym3_SRP107342	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.4681
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942934
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06385
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.869946
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58194
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53412
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6697_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.39637
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45833
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSII associated light-harvesting complex II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.531
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855051
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
QE-00-EB96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289683
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915901
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12914_KD_FUT8_SRP342334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2231
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX10_KO_GDS3480_257_rat_Schwannoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832159
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.960853
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48829
GTEX-R55C-1026-SM-48FCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17795
Adrenocortical carcinoma_ACC_TCGA-OR-A5JF-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055255
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411745
hsa-miR-4763-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Hypb_Deficiency_GDS3641_522_mouse_Yolk sac from E9 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
E2F1_KD_GDS4094_446_mouse_Mammary tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201443
EW22	DepMap CRISPR Gene Dependency	1.0	5.20598
hsa-miR-330-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40546
RAF1_activemutant_219_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.56952
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17955
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17282_KO_Hsf5_SRP345601	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-S341-0426-SM-4AD5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19369
BL9277 (PIK3R4)	NURSA Protein Complexes	1.0	null
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.860553
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25449
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, anterior part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05602
ROCK_INHIBITION_GDS3944_464_mouse_Forebrain astrocytes - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE150215_1_v_2_etl4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8107
Sarcoma_SARC_TCGA-QQ-A5V9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42263
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30199
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.02943
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25675
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_6_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46616
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE136233,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8092
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.10808
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11815
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-P78B-1126-SM-3P615	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840003
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231807
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3335
GTEX-X5EB-1426-SM-46MVW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956252
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855231
GTEX-WFG8-1026-SM-4LVMZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32837
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7077-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IST-SL2	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253812
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71387
mantle zone of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0847
HIST1H4F	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25346
SRSF3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210476_9_v_5_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.5682
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51601
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91592
19305503-TableS1	GeneSigDB Published Gene Signatures	1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08127
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.900429
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45051
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1475
OE19	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1954	CCLE Cell Line Gene CNV Profiles	1.0	2.63335
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04046
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07189
GTEX-SE5C-1326-SM-4BRUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23261
KE37	DepMap CRISPR Gene Dependency	1.0	4.60424
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CALU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36838
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13991
PMC6529937-Table_1.xlsx-IRF1_dependent_upregulated-gene_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09963
CTSG	Pathway Commons Protein-Protein Interactions	1.0	null
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39237
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRF	MotifMap Predicted Transcription Factor Targets	1.0	null
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10466
PFKFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37521
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.32708
S0-EE-Y6WJ_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232018
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21304
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17179
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27827
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.02858
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07712
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43547
bronchus	HPA Tissue Protein Expression Profiles	1.0	3.20909
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242901
P2URK562	DepMap CRISPR Gene Dependency	1.0	3.17924
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Diabetes Mellitus, Type 1	HuGE Navigator Gene-Phenotype Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04944
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19363
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.62234
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.67141
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.48165
mRNA_TBX3_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832546
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933359
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.27963
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62775
hsa-miR-4309	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85439
Infertility, Female	CTD Gene-Disease Associations	1.0	1.25494
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0926-SM-447BR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93762
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864966
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-128	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8469
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.43551
hsa-miR-421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24466
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61676
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039998
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.827313
RPS6	Pathway Commons Protein-Protein Interactions	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897534
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31646
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259705
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30091
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.880289
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824721
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.52579
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.978023
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-50	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.725732
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.52341
Adrenocortical carcinoma_ACC_TCGA-OR-A5K6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.429597
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03221
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.988504
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991501
TMEM14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41833
ZSWIM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67342
Lung adenocarcinoma_LUAD_TCGA-55-6984-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EXOSC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78429
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19934
ZNF143	ENCODE Transcription Factor Targets	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401508
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31732
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37427
Perturb_13850_KO_RET_ERP126468	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-361-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Choline	CTD Gene-Chemical Interactions	1.0	null
POLR3C	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.890609
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364919
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0555
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40121
AR	ChEA Transcription Factor Targets	1.0	null
Transcription factor TFIIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38906
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.267035
ONS76	DepMap CRISPR Gene Dependency	1.0	2.35878
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2618
hsa-miR-4460	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
hsa-miR-3922-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245084
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.127648
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.41496
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59615
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5873
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89282
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89782
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	2.52247
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67252
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
hsa-miR-1976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-WFJO-0726-SM-4LVM8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00311
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243012
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973454
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SALL4	ChEA Transcription Factor Targets	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895984
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-508-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE226452_1_v_2_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898252
RBM28	Pathway Commons Protein-Protein Interactions	1.0	null
G3BP2	Pathway Commons Protein-Protein Interactions	1.0	null
EIF3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56231
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15467
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.89922
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04693
Fibrillar center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.100545
RPA2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2517
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-1726-SM-4LVM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39514
GTEX-XYKS-1026-SM-4BRVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12834
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10482
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
spleen	HPA Tissue Protein Expression Profiles	1.0	1.91965
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
OC-71-BZ81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214301
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98332
D423MG	DepMap CRISPR Gene Dependency	1.0	2.74474
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04709
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31669
GTEX-UJMC-1026-SM-4IHKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13033
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-0426-SM-4LVM7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30012
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57289
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.08947
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04507
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.450629
PKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29381
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5505
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9346
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7534
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6661
FYTTD1	Pathway Commons Protein-Protein Interactions	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417644
diethylstilbestrol_mus musculus_gpl81_gds982	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUZC-0526-SM-4BOPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04155
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5008_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.34676
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LYRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22019
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39492
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.23673
SCA7_Knock-in_GDS3545_560_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934535
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41244
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50097
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6836-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15091
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35187
GTEX-S7SF-0626-SM-4AD4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871055
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22004
USF2	ENCODE Transcription Factor Targets	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23083
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372614
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28329
NB13	DepMap CRISPR Gene Dependency	1.0	3.06935
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07396
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14778
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.992045
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21072
Weight Gain	CTD Gene-Disease Associations	1.0	1.17497
DE-99-OT37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266714
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0062
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28216
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15226
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.811821
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201771
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67157
mantle zone of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17832
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE134986_2_v_8_oma1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GK_KO_GDS2610_162_mouse_Brown adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55D-1226-SM-48FE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11615
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263539
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.71896
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380058
BB-63-AW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207834
chr8_117009233_A_G_b38	GTEx eQTL 2025	1.0	1.00182
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91422
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.302825
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.043697
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2137
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.57407
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.947
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288085
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12957
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15398
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33878
PMC10290283-biol-2022-0622-sm3.pdf-325-TCF7L1_TCF7L1	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1796
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2375
mRNA_NANOG_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254109
GTEX-PSDG-1426-SM-48TD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40982
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lung development	GO Biological Process Annotations 2015	1.0	null
RPL31	Pathway Commons Protein-Protein Interactions	1.0	null
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02501
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09311
SLR23	DepMap CRISPR Gene Dependency	1.0	2.31535
Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62884
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-HSLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118315
GTEX-OIZH-0726-SM-3NB1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26727
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16716
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32098
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07425
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01258
CLDN18_KO_GDS4961_28_mouse_whole lung tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051837
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36194
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00382
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960025
BV-173	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
Perturb_17262_OE_Foxj2_SRP368260	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.045
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68721
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326087
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13238
GTEX-V955-1026-SM-4JBHO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11813
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18952
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898772
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.07128
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.344818
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49923
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46616
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-R55C-0726-SM-48FCN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4392
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0708
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040625
EP300_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-651	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SALL4-18804426-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.812493
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245804
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
hsa-miR-28-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
E2F1	ChEA Transcription Factor Targets	1.0	null
SGF29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2574
HDAC2	ENCODE Transcription Factor Targets	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.030545
mRNA_ESRRB_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32907
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1794
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.05828
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.47691
Liver Diseases	CTD Gene-Disease Associations	1.0	1.24781
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GS-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU7-1426-SM-4BRWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25267
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8663
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10482
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31409
NCIH441	DepMap CRISPR Gene Dependency	1.0	6.66658
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67374
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.57407
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3511
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE241701_1_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNRPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69454
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833884
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860568
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74363
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80842
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833884
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Multiple acyl-CoA dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
SRP14	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-IW-A3M4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_9752_KO_Rnf20/Rnf40_SRP228497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.6424
GTEX-WFG7-1026-SM-4LMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32479
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26294
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28405
HCC1419	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_25_OE_Patz1_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.65469
GTEX-S4P3-0726-SM-4AD57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24367
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23191
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.462602
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.097
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3629
outer SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927882
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.62359
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substantia innominata/basal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20598
GTEX-UJHI-1026-SM-4IHJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888819
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09322
GTEX-P4QT-1526-SM-3NMCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11353
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052542
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30541
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01109
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21921
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.713233
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.76582
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29379
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Ovary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342299
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1428	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
CLDN18_KO_GSE48443_44_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149075_8_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51468
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38118
PMC7334247-12031_2020_1490_MOESM2_ESM.xls-THAP1_S21T_vs_wt-Gene_Symbol_THAP1	Rummagene Transcription Factor Associations 2026	1.0	null
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29249
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22244
myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.243645
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4263_KO_OTX2_SRP388433	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.66896
GTEX-P4QS-0726-SM-3NMCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22457
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07034
Sarcoma_SARC_TCGA-FX-A3RE-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	2.71914
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05066
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T5JC-1226-SM-4DM7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856526
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38326
GSE166004_5_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1419	DepMap CRISPR Gene Dependency	1.0	4.64983
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.46754
GTEX-PWOO-1026-SM-48TCN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07105
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5972
MUTZ8	DepMap CRISPR Gene Dependency	1.0	3.9139
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24191
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.46356
GTEX-NFK9-1526-SM-3LK7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15084
hsa-miR-371b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82988
GTEX-WFG7-1226-SM-4LMK2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77404
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89945
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.832
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325881
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4968
APEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26654
FKBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02727
GTEX-XUJ4-0926-SM-4BOPA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24248
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907693
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.93142
HT29	CCLE Cell Line Gene CNV Profiles	1.0	1.64548
PrPC_KO_GDS4352_358_mouse_Developing hippocampus from FVB newborns (4.5-day-old)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BFTC909	CCLE Cell Line Gene CNV Profiles	1.0	1.72966
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02564
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.923429
GSE184902_3_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10045
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26621
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16877
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2373
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831108
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40373
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRP9	Pathway Commons Protein-Protein Interactions	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.16001
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-2.76445
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69967
S0-EE-Y6WJ_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202953
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26916
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833884
EA-93-KT88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269542
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60099
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HSOS1	DepMap CRISPR Gene Dependency	1.0	5.03048
dexamethasone_homo sapiens_gpl6480_gds3946	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91252
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.64397
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.57928
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12163_KD_OVOL1_SRP352292	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.27025
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46897
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01717
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2	ChEA Transcription Factor Targets	1.0	null
KLF15_Deficiency_GDS2687_648_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10816
SKM-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5986
Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893018
BRG1_DEPLETION_GDS2156_720_mouse_Embryos (maternally depleted)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254779
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.29941
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
AZU1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.036981
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22806
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_69_KD_SMARCB1_SRP280151	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.8239
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25398
G3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_5171_KO_Sirt1_SRP075247	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24525
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21611
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Q7-0926-SM-4AD5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0238
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337699
developmental process	GO Biological Process Annotations 2015	1.0	null
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07646
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06918
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96523
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997045
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271459
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961458
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20545
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59088
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1681
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13788
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28996
hsa-miR-27b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06394
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4642
lateral preoptic area, PO1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07236
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.974966
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29R-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4P3-0526-SM-4AD58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6663
H3K27me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LU-65	COSMIC Cell Line Gene CNV Profiles	1.0	2.22291
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265831
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11772
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.80607
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22726
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0926-SM-4DXU5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962329
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0626-SM-48FD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26121
GSE81803,GSE81912_4_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AML193	DepMap CRISPR Gene Dependency	1.0	2.17163
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0273
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66313
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42781
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13884
NB4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04412
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952555
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
SUB1	Pathway Commons Protein-Protein Interactions	1.0	null
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24202
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.27101
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0726-SM-48TDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29623
GTEX-XPVG-1426-SM-4B668	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07325
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17026
GSE166004_5_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4375
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPM-0726-SM-3LK7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07495
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_768_mouse_Skin - 7 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08047
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00095
CBX2_KO_GDS4445_354_mouse_E11.5 XY embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12043
Prostate adenocarcinoma_PRAD_TCGA-EJ-5511-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09928
AD-09-MD49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395063
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18526
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18203
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40834
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADAMTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10045
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
GTEX-QDT8-0626-SM-48TYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62565
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20443
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0167
NUGC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38156
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371245
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64476
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55602
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Orde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17927
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25344
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06345
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204923
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24509
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72003
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BANF1	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNASE3	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.88162
GTEX-V955-1226-SM-4JBI9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49299
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971359
Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138818_2_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914115
ZNF263	ENCODE Transcription Factor Targets	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76751
LIG3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06059
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900115
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905718
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6565
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.95952
FOXP2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13309
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70715
Trichorhinophalangeal syndrome type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Hypospadias	CTD Gene-Disease Associations	1.0	1.25525
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207461
hsa-miR-4422	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
TOP1	Pathway Commons Protein-Protein Interactions	1.0	null
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29651
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-BACH1_BACH1	Rummagene Transcription Factor Associations 2026	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2274
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4724-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24191
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.451428
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3037
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.016
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cornelia de Lange syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.649308
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Epiblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.965291
GTEX-RU72-0826-SM-46MUS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880094
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273631
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865444
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.1869
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57076
Lung adenocarcinoma_LUAD_TCGA-62-8395-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29512
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53412
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041294
ZMPSTE24_Deficiency_GDS3775_506_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WH7G-1526-SM-4LVMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86397
GTEX-S95S-0326-SM-4B66U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13965
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2621
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38606
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54336
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01181
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC2935	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96744
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22098
MAP3K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33192
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36531
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05025