association	dataset	threshold value	standardized value
LN340	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89172
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062225
abnormality of cardiovascular system physiology	HPO Gene-Disease Associations	1.0	null
BRD-K68174511_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hemorrhage of the eye	HPO Gene-Disease Associations	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49627
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SREBP1-19666523-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hepatitis B	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36826
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
abnormality of refraction	HPO Gene-Disease Associations	1.0	null
Nevus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K48557872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33879
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.77861
presence	GeneRIF Biological Term Annotations	1.0	null
calmidazolium-906	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83919
BRD-A84923154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20274
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.780954
abnormal eye morphology	MPO Gene-Phenotype Associations	1.0	null
adenocarcinoma	GeneRIF Biological Term Annotations	1.0	null
heterozygous	GeneRIF Biological Term Annotations	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15404
BRD-K76147162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21104
Cerebral Hemorrhage	CTD Gene-Disease Associations	1.0	1.63899
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39834
INTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66669
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07239
located	GeneRIF Biological Term Annotations	1.0	null
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1046
Intermittent claudication	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.296
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63454
GSE133516_5_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
plasma membrane part	LOCATE Curated Protein Localization Annotations	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11175
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.143094
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0444
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.789
BRD-K72636697_QL-X-138_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33065
induces	GeneRIF Biological Term Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14708
Renal Insufficiency, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
increase	GeneRIF Biological Term Annotations	1.0	null
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00133
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56911
BRD-K54862370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32284
hsa-miR-760	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18734
exists	GeneRIF Biological Term Annotations	1.0	null
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.301008
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987753
valproic acid-2700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal cardiovascular system morphology	MPO Gene-Phenotype Associations	1.0	null
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13314
BRD-K23363278_CYT997_A549_24.0_h_1.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13772
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38413
Prostatic Neoplasms	CTD Gene-Disease Associations	1.0	1.22242
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1931
KYSE-520	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.93304
rearrangements	GeneRIF Biological Term Annotations	1.0	null
Migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
hsa-miR-3614-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Cutis Laxa	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32404
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876303
BRD-K33956641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11847
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81086
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77221
membrane region	GO Cellular Component Annotations 2015	1.0	null
BRD-K55835264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21475
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32697
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K62536891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22084
Hyperphosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2684
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97479
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04127
CLPP_KO_GSE40207_381_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
scoliosis	HPO Gene-Disease Associations	1.0	null
GTEX-S7SF-1926-SM-4AT5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04396
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52121
crotamiton-3050	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36779
interactions	GeneRIF Biological Term Annotations	1.0	null
pattern	GeneRIF Biological Term Annotations	1.0	null
Rhabdomyolysis	CTD Gene-Disease Associations	1.0	1.18554
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04269
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50387
BRD-K01676126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45433
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24971
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0333
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92458
calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.581217
obesity	GWASdb SNP-Disease Associations	1.0	0.655831
BRD-K42145213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90235
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9363
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7931
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.964
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13553
REST	ENCODE Transcription Factor Targets	1.0	null
Basal part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.2
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.839454
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33254
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06877
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal genital system morphology	GWASdb SNP-Phenotype Associations	1.0	0.121357
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2372
Descending Perineum Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Myasthenia Gravis	DisGeNET Gene-Disease Associations	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918321
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kmp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
Rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.208
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33658
BRD-A46747628_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Red blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.61549
endoplasmic reticulum part	GO Cellular Component Annotations 2015	1.0	null
abnormality of humoral immunity	GWASdb SNP-Phenotype Associations	1.0	0.326976
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.861923
PMC6258166__F6	PFOCR Pathway Figure Associations 2024	1.0	null
KYSE-410	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.1407
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990309
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16286
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00981
benzathine benzylpenicillin-4022	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
additional	GeneRIF Biological Term Annotations	1.0	null
BRD-K70305913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84092
BRD-K43620258_3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide_MCF7_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K60834597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10496
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50168500_canertinib_BT20_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
16790086-tableW1	GeneSigDB Published Gene Signatures	1.0	null
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Muscular Diseases	CTD Gene-Disease Associations	1.0	1.51506
variable	GeneRIF Biological Term Annotations	1.0	null
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872627
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94790210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06504
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.61883
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.35568
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33783
AU565	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K12343256_trametinib_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNCA_KO_GDS4153_528_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
carbenoxolone-3014	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vacuole-isolation membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
SNU308	CCLE Cell Line Gene CNV Profiles	1.0	2.08378
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00016
trichostatin A-2208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20353
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33767317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98375
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21896
Progeroid syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
BRD-A39996500_radicicol_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
gastrointestinal tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.318635
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC10787250-BLOODA_ADV-2022-008899-mmc1.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_commonly_up-_or_downregulated_in_CBFA2T3_GLIS2_leukemia_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
transmembrane	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31263
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90905
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.856053
NUP93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31976
cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.32774
Perturb_15133_OE_Klf10_SRP360603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.9883
underlying	GeneRIF Biological Term Annotations	1.0	null
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35708
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TH-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93990956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15463
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78384
leading	GeneRIF Biological Term Annotations	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pepstatin-4206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.436137
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.159461
autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14283
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59044
BRD-K08806664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07577
correlated	GeneRIF Biological Term Annotations	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987841
glycocholic acid-6716	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077182
suprofen-3343	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.980942
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26225
BRD-K34318928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66257
Probenecid	HMDB Metabolites of Enzymes	1.0	null
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04067
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Celiac Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55607
BRD-K31699485_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.383
BRD-K03540982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25951
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0183
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	3.40809
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
consisting	GeneRIF Biological Term Annotations	1.0	null
diclofenamide-3027	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45395
Thrombocytopenia	CTD Gene-Disease Associations	1.0	1.77257
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41736
abnormality of skin morphology	HPO Gene-Disease Associations	1.0	null
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10388
Nickel	CTD Gene-Chemical Interactions	1.0	null
BRD-A39996500_radicicol_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28842
Hematocrit	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.32218
ectopic calcification	HPO Gene-Disease Associations	1.0	null
Confusion	CTD Gene-Disease Associations	1.0	1.62199
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Angina	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K77987382_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15956
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01797
BRD-K76609014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28266
decreased sterol level	MPO Gene-Phenotype Associations	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38403
hemiplegia/hemiparesis	HPO Gene-Disease Associations	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
496100672_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1556
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.834045
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51554
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43506
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26599
BRD-K92018859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65774
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fulvestrant-1076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular	GeneRIF Biological Term Annotations	1.0	null
Neutropenia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K77498991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15854
ATXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0325
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03408
Vertebral artery occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
hsa-miR-4649-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the endocardium	HPO Gene-Disease Associations	1.0	null
BRD-K62289640_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11248
amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.285802
prevents	GeneRIF Biological Term Annotations	1.0	null
Heart aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
tetroquinone-2999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78593
sublayer 6a of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17182
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925374
BRD-K73573019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7174
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.946125
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6583
blood vessel wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214765
layer 5 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61014
Calu-6	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.68845
SW962	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.2004
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.48486
layer 6 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17665
synthetic	GeneRIF Biological Term Annotations	1.0	null
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991288
sites	GeneRIF Biological Term Annotations	1.0	null
NCIH1836	CCLE Cell Line Gene CNV Profiles	-1.0	-2.47012
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17322
BRD-K89801935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57007
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44719
fulvestrant-2698	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00144
UBA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72691
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08407
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11325
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315498
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nephrocalcinosis	HPO Gene-Disease Associations	1.0	null
Perturb_8893_OE_YAP1_SRP151027	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.9711
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
infarction	GeneRIF Biological Term Annotations	1.0	null
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Indomethacin	DrugBank Drug Targets	1.0	null
BRD-K15160749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45491
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833603
brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219485
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97545
genomic	GeneRIF Biological Term Annotations	1.0	null
16266895-Figure1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15997423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11499
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13609
Arrhythmias, Cardiac	CTD Gene-Disease Associations	1.0	1.37103
Hyperinsulinemic hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7156-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
BRD-K40841951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51655
Arterial calcification of infancy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
brain endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175847
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92594
Calcification Of Falx Cerebri	DisGeNET Gene-Disease Associations	1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08819
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00761
SARS-CoV MA15_Day7-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66294
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24937
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
KARPAS-620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K80782159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36377
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53615
among	GeneRIF Biological Term Annotations	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11015
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892595
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06351
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942939
BRD-A20208638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20176
trichostatin A-2721	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SW1116	GDSC Cell Line Gene Expression Profiles	1.0	1.71136
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06515
Cerebral Hemorrhage	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K61335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06993
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.936933
Beta^+^ Thalassemia	DisGeNET Gene-Disease Associations	1.0	null
ZBTB33_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sharply	GeneRIF Biological Term Annotations	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.9
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76236
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58997
Mental Disorders	CTD Gene-Disease Associations	1.0	1.65974
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31546
HT55	GDSC Cell Line Gene Expression Profiles	1.0	1.51205
SALL4-18804426-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Anemia	DisGeNET Gene-Disease Associations	1.0	null
gonadal neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.345213
BRD-K98490050_AMSACRINE_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K40990712_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84069
Benzbromarone	CTD Gene-Chemical Interactions	1.0	null
BRD-K17743125_belinostat_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Basolateral plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
nine	GeneRIF Biological Term Annotations	1.0	null
BRD-K48634117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01337
BRD-K68174511_torin-2_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE180525,GSE180528_2_v_3_tbx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.32015
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059935
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69688
BRD-K68174511_torin-2_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68199
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAP1-22055183-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
sisomicin-4014	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mediate	GeneRIF Biological Term Annotations	1.0	null
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05066
BRD-K24132293_piperlongumine (HPLC)_SNGM_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K62781263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19314
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930588
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298165
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.033
LTB4R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00493886
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Polycistic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19484
BRD-K28907958_-666_A549_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.579
testing	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882675
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896051
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
phosphate ion homeostasis	GO Biological Process Annotations 2025	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NH-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.935736
ABC-type glutathione S-conjugate transporter activity	GO Molecular Function Annotations 2025	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084444
Fabry disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14606
GTEX-XQ3S-1326-SM-4BOPQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09725
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1009
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.85852
Hereditary combined deficiency of vitamin K-dependent clotting factors	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.03
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.24363
BRD-K23782109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28598
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18955
abnormality of the retina	HPO Gene-Disease Associations	1.0	null
Stricture Of Artery	DisGeNET Gene-Phenotype Associations	1.0	null
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33791
BRD-K90902537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15292
PRKCA_KO_GDS2141_300_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNU-C5	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.97495
BRD-K16118047_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53619
Vascular Calcification	DisGeNET Gene-Phenotype Associations	1.0	null
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal elasticity of skin	HPO Gene-Disease Associations	1.0	null
BRD-K87593103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66063
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6973
BRD-K25846934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03892
Gonadal Disorders	CTD Gene-Disease Associations	1.0	1.14954
15-delta prostaglandin J2-6948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
rather	GeneRIF Biological Term Annotations	1.0	null
thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.178403
BRD-A58955223_L-sulforophane_AGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ABC transporter type 1, transmembrane domain	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K51335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50939
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04815
PMC12255818-41467_2025_61448_MOESM1_ESM.pdf-51-NFIB_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31542390_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
joint hypermobility	HPO Gene-Disease Associations	1.0	null
ABC transporter, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.101
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30408
BB-20-UU03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268696
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884873
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869178
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09965
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38234
ATP binding	GO Molecular Function Annotations 2025	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6555
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THALIDOMIDE	DGIdb Drug Targets 2026	1.0	0.572238
Kidney Tubular Necrosis, Acute	CTD Gene-Disease Associations	1.0	1.50398
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
647-V	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53253
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.62468
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21724
haloperidol-1203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870145
PMC10645393-jci-133-169200-s102.xlsx-Table_S14_AR-V_DNA-PK_DEGs-Supplementary_Table_14_Overlapping_DEG_list_from_CWR22Rv1-AR-EK_cells_depleted_of_AR-V7_and_treated_with_DNA-PK_inhibitor_NU5455_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Blood vessel wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.509
Carcinoma, Renal Cell	CTD Gene-Disease Associations	1.0	1.20848
VCL	Pathway Commons Protein-Protein Interactions	1.0	null
Developmental Disabilities	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998963
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
RCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06661
intermediate stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16198
Extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.511
Doxorubicin	DrugBank Drug Targets	1.0	null
BRD-K23405293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25009
Mitral Valve Stenosis	DisGeNET Gene-Disease Associations	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879251
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983997
BL754 (CSNK2A1)	NURSA Protein Complexes	1.0	null
twentythree	GeneRIF Biological Term Annotations	1.0	null
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18414
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3588
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17093
CRYL1	Pathway Commons Protein-Protein Interactions	1.0	null
decreased circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
BRD-K14780713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02729
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48419
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pseudoxanthoma Elasticum	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K28446462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00227
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW13	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54193
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73142
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72591
Perturb_14900_KO_H15_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.31046
piperidolate-6772	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chaperone	GeneRIF Biological Term Annotations	1.0	null
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40243
cingulate cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_14890_KO_H15_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.44486
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.28
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32507
Perturb_17251_KO_Il17ra_SRP069071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.9392
BRD-K07534805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23557
Ureteral benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8518-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the genital system	GWASdb SNP-Phenotype Associations	1.0	0.105998
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
hsa-miR-2053	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K09378334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05037
brinzolamide-6670	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dysfunction	GeneRIF Biological Term Annotations	1.0	null
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41871
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.855052
abnormal bruch membrane morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950225
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34834
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K87277021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21337
sequence	GeneRIF Biological Term Annotations	1.0	null
Perturb_4237_OE_ERG/FLI1_SRP403488	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.39197
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16312
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vinblastine	HMDB Metabolites of Enzymes	1.0	null
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15378
setting	GeneRIF Biological Term Annotations	1.0	null
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43861
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1671
IGROV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
localized scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25983
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08459
Supramolecular fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.441
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BL8731 (MLLT1)	NURSA Protein Complexes	1.0	null
release	GeneRIF Biological Term Annotations	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082506
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02186
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09997
hepatic	GeneRIF Biological Term Annotations	1.0	null
CRCGN013_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01479
Coronary Artery Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
macule	HPO Gene-Disease Associations	1.0	null
uremia	MPO Gene-Phenotype Associations	1.0	null
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40743
BRD-K62459624_T5212475_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10079
BRD-K21996189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26909
SEC61A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63642
SW1271	CCLE Cell Line Gene CNV Profiles	1.0	1.58468
medial calcification of large arteries	HPO Gene-Disease Associations	1.0	null
Thickened Nuchal Skin Fold	DisGeNET Gene-Phenotype Associations	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K13804959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56231
Collagen disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3305
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34736
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.279659
Renal pyramid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver Failure, Acute	CTD Gene-Disease Associations	1.0	1.55206
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51117
BRD-A39996500_radicicol_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
B-CPAP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13722
hsa-miR-4769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Metabolic Syndrome X	HuGE Navigator Gene-Phenotype Associations	1.0	null
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25091
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71058
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054696
BRD-K71123535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18652
hsa-miR-199a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29338
Tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09365
BRD-K82658511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27937
riboflavin-1767	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121941
Intervertebral disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
precuneus, left, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12177
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K46056750_AZD-7762_SKBR3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Coronary aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
PMC5553784__F3	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K57464717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05632
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68052
Multiple Chronic Conditions	DisGeNET Gene-Disease Associations	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.726462
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04415
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.34699
confirm	GeneRIF Biological Term Annotations	1.0	null
FURIN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE183251_1_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.098
Warfarin	CTD Gene-Chemical Interactions	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59796
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mechanisms	GeneRIF Biological Term Annotations	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
nucleotidebinding	GeneRIF Biological Term Annotations	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995985
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836398
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21385
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH596	CCLE Cell Line Gene CNV Profiles	1.0	2.43363
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3542
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824167
Homocystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.891005
A549_Tozasertib_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142969
ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095596
ATP transport	GO Biological Process Annotations 2023	1.0	null
ciprofloxacin-2022	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49506
BRD-K26161397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80688
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35037
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPK-0526-SM-2HMJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883721
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52094
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97804
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0924
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23425
nucleotide	GeneRIF Biological Term Annotations	1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51109
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02576
BRD-K27621887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09766
BRD-K59028365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28451
causative	GeneRIF Biological Term Annotations	1.0	null
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
BRD-K95963125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20811
Amyloidosis	DisGeNET Gene-Disease Associations	1.0	null
TAL1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28842
TCF3	ENCODE Transcription Factor Targets	1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40904
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
reticulum	GeneRIF Biological Term Annotations	1.0	null
purine ribonucleotide metabolic process	GO Biological Process Annotations 2023	1.0	null
Cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.644
GSE62843,GSE64371_2_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825892
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20303
BRD-K91980109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17868
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dactinomycin	DrugBank Drug Targets	1.0	null
suggesting	GeneRIF Biological Term Annotations	1.0	null
nucleoside-triphosphatase activity	GO Molecular Function Annotations 2015	1.0	null
Azotemia	CTD Gene-Disease Associations	1.0	1.48813
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12014
GATA1_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D-423MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42888
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-6217-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ethambutol-4001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-505	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.269
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930938
purine ribonucleotide metabolic process	GO Biological Process Annotations 2025	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.961967
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Kibra-Ex-Mer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37186
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824875
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56373
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851411
Thyroid Neoplasms	CTD Gene-Disease Associations	1.0	1.13552
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17746
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2719
calcified retina	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4676-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.89793
retaining	GeneRIF Biological Term Annotations	1.0	null
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07456
membrane part	GO Cellular Component Annotations 2015	1.0	null
microvascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142068
result	GeneRIF Biological Term Annotations	1.0	null
BRD-K86761848_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
methanthelinium bromide-6254	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04588
Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Familial Mediterranean Fever	DisGeNET Gene-Disease Associations	1.0	null
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922839
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
mitochondria-associated endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
Intracranial Hemorrhages	CTD Gene-Disease Associations	1.0	1.27905
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2069
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.20229
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28629
gabapentin-2731	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
D283MED	CCLE Cell Line Gene Expression Profiles	1.0	1.53833
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82982
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.84107
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32428
reproductive organ cancer	GWASdb SNP-Disease Associations	1.0	0.238765
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24329
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8439554__F1	PFOCR Pathway Figure Associations 2024	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55157
BRD-K58853583_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831709
CYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55624
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
BRD-K97810537_beclomethasone_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bicuculline-2139	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224877_2_v_1_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
male reproductive organ cancer	GWASdb SNP-Disease Associations	1.0	0.393421
Prostate adenocarcinoma_PRAD_TCGA-V1-A8X3-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6671_KO_KLB_SRP386785	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72315
lesions	GeneRIF Biological Term Annotations	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.382508
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99380757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33221
BRD-K92571446_WZ-3105_HEPG2_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-3620	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K89216747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5814
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8394
counselling	GeneRIF Biological Term Annotations	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	1.0	2.10667
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0264
BRD-A87137733_GSK-690693_SKBR3_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19831
ONS-76	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15416
Fluorouracil	CTD Gene-Chemical Interactions	1.0	null
BRD-K58853583_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72667
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0677
HEPG2	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940559
Spherical high-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17873
three	GeneRIF Biological Term Annotations	1.0	null
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20272
A-498 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.92887
Abnormally Lax Or Hyperextensible Skin	DisGeNET Gene-Phenotype Associations	1.0	null
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0277
BRD-K85554193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09034
Carcinoma, Squamous Cell	CTD Gene-Disease Associations	1.0	1.31178
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.44714
BRD-K13515483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73025
GTEX-P4PQ-0526-SM-2HMKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46155
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42065
Perturb_14602_KD_PAR1_SRP273320	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.41851
stroke	GeneRIF Biological Term Annotations	1.0	null
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32126
Transient cerebral ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
BRD-K73824630_SKATOLE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840873
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.305226
BRD-K61494613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98039
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12387
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATP13A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06659
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17357
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.904375
BRD-K13090434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09546
BRD-K43719900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18256
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874889
BRD-K82823804_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K83135157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34194
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52258
Jaundice	DisGeNET Gene-Disease Associations	1.0	null
BRD-K79523827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50365
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gallamine triethiodide-1375	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00367
Abdominal aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.421
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22013
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85365
C2BBe1	GDSC Cell Line Gene Expression Profiles	1.0	2.09163
RAGE_knockout_268_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.54304
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37659
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE230263,GSE230265_3_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Probenecid	DrugBank Drug Targets	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.5483
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.536
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Leukopenia	CTD Gene-Disease Associations	1.0	1.34694
LY-294002-6976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
visual perception	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6511-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5637726__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888129
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71814
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06994
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Stargardt disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.938456
Chondrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21917
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93577
Primary somatosensory area, barrel field, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02473
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04321
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.80761
intracranial hemorrhage	HPO Gene-Disease Associations	1.0	null
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Arthropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35503
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5169
Vascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
dichroism	GeneRIF Biological Term Annotations	1.0	null
fibres	GeneRIF Biological Term Annotations	1.0	null
Age Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41234
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83836
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17766
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08033
GSE180575_1_v_0_fmo5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3742
gene expression	GO Biological Process Annotations 2023	1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.933052
BL1741 (CDK7)	NURSA Protein Complexes	1.0	null
dnabinding	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4102-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spectinomycin-4773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Neointima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
abcc6	GeneRIF Biological Term Annotations	1.0	null
BRD-K16991828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40937
most	GeneRIF Biological Term Annotations	1.0	null
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.484326
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.70779
abnormality of forebrain morphology	HPO Gene-Disease Associations	1.0	null
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.046
BRD-K99252563_QL-XII-47_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SF295	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.49838
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6395-01A-13R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.48479
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00797068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14403
Lung adenocarcinoma_LUAD_TCGA-97-A4M0-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4099
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.887
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.206
BACH1	ChEA Transcription Factor Targets	1.0	null
GSE88819_5_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89166
BtuCD complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.328
HuH-7	GDSC Cell Line Gene Expression Profiles	1.0	2.08377
abnormality of the atrioventricular valves	HPO Gene-Disease Associations	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.950255
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LNCAP	BioGPS Cell Line Gene Expression Profiles	1.0	1.0603
ajmaline-7484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05104363_PD-184352_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tibialis posterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.577615
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35984
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02833
Calcinosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0833
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929754
Headache	CTD Gene-Disease Associations	1.0	1.42129
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45457
E2F3_KD_GDS4094_448_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
displays	GeneRIF Biological Term Annotations	1.0	null
GSE73381,GSE73382_0_v_1_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart Failure	CTD Gene-Disease Associations	1.0	1.5382
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48611
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46328
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83386
gastrointestinal system cancer	GWASdb SNP-Disease Associations	1.0	0.143641
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893153
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27545
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087748
proof	GeneRIF Biological Term Annotations	1.0	null
PMC7887252__F8	PFOCR Pathway Figure Associations 2023	1.0	null
SHARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19143
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.617
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68445
hypersensitivity reaction type ii disease	GWASdb SNP-Disease Associations	1.0	1.00407
BRD-K37687095_AZD-8330_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lymphadenopathy	DisGeNET Gene-Phenotype Associations	1.0	null
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GMP reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metabolite	GeneRIF Biological Term Annotations	1.0	null
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911594
GSE246053_4_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826263
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.80787
abnormality of vision	HPO Gene-Disease Associations	1.0	null
BRD-K76401790_JNK-IN-5A_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11556
DOK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4LX-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.67933
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03721
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30919
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.881663
Perturb_11373_KD_USP22_SRP229365	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.97559
BRD-K25952063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52165
BRD-K19852577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08445
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.8665
transport	GO Biological Process Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00939
CORL95	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47805
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.944
Metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990174
distribution	GeneRIF Biological Term Annotations	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929754
Age related macular degeneration 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
cause	GeneRIF Biological Term Annotations	1.0	null
BRD-K63394284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4406
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33025
abnormality of coagulation	HPO Gene-Disease Associations	1.0	null
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K61439332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06207
GSE128333_3_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98248
Defective ABCC6 causes PXE	Reactome Pathways 2024	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7286-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08895
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17766
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40975
SH-EP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.61529
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21562
Dermal fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.739
BRD-K69932463_AZD8055_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
chloropyrazine-6227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.047
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K69528787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2808
late-onset retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.11631
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.729372
vascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.152248
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.823
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.954
restrictive cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.312464
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4978
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54103
BRD-K76723780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32978
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.88126
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.157
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66644
BRD-K45289917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58263
Polyhydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
consequences	GeneRIF Biological Term Annotations	1.0	null
ERCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03292
BRD-K59560948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51337
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.992814
Mitral Valve Prolapse Syndrome	DisGeNET Gene-Disease Associations	1.0	null
seems	GeneRIF Biological Term Annotations	1.0	null
layer 3 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28904
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Posterior parietal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52814
BRD-K58762810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08526
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
case	GeneRIF Biological Term Annotations	1.0	null
circulating	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09976
BRD-K90686530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16397
imbalance	GeneRIF Biological Term Annotations	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77199
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Renal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
BRD-K34110797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02341
liverspecific	GeneRIF Biological Term Annotations	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.804026
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
expressing	GeneRIF Biological Term Annotations	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15877
Blood protein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissue	GeneRIF Biological Term Annotations	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843453
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38966
endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
NA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
BRD-K97486995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57406
lateral part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
specific	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841748
hsa-miR-4701-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.087
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83253
KOPN-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18176
superficial stratum of CCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72875
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24722
absence	GeneRIF Biological Term Annotations	1.0	null
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893048
BRD-K15654812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27356
NCIH69	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78359
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aztreonam-1435	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57917
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29806
Brain Lower Grade Glioma_LGG_TCGA-HT-7611-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2998-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Porencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
RPS6KA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18249
linkage	GeneRIF Biological Term Annotations	1.0	null
BHLHE40_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESC_V6.5_UP_EARLY.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964935
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927837
arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.198709
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877874
neoplasm of the genitourinary tract	GWASdb SNP-Phenotype Associations	1.0	0.194079
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34363
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7264
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58176
estradiol-988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999068
BRD-K23905877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.83443
Aortic valve stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
nonsense	GeneRIF Biological Term Annotations	1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
CLPP_KO_GDS4791_543_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
GADD45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72031
Fetalliver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
metformin-1	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054314
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.931
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58635
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
econazole-7305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
transported	GeneRIF Biological Term Annotations	1.0	null
GTEX-WY7C-2726-SM-3NB3P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4314
Cholangiocarcinoma	CTD Gene-Disease Associations	1.0	1.04574
BRD-K76694128_DCC-2036_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01862
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0283
membrane	GeneRIF Biological Term Annotations	1.0	null
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07119
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.90565
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.250207
BRD-K67484361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10724
Hypercholesterolemia	CTD Gene-Disease Associations	1.0	1.17662
BRD-K49865102_PD-0325901_HT29_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7142
Excessive Wrinkled Skin	DisGeNET Gene-Phenotype Associations	1.0	null
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221989
inner CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10436
Prostate adenocarcinoma_PRAD_TCGA-HC-7750-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857984
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE108547_2_v_0_a1cf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58824
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-1026-SM-4DM72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00483
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.996228
Reduced Visual Acuity	DisGeNET Gene-Phenotype Associations	1.0	null
aplasia/hypoplasia of the skin	HPO Gene-Disease Associations	1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07837
BRD-K11566982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21975
rhein	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05319
skin	HPA Tissue Gene Expression Profiles	-1.0	-0.994234
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.045854
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38699
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intestinal cancer	GWASdb SNP-Disease Associations	1.0	0.458465
suppressed	GeneRIF Biological Term Annotations	1.0	null
SRSF7_02_06	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.95936
cerebral calcification	HPO Gene-Disease Associations	1.0	null
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862375
colorectal cancer	GWASdb SNP-Disease Associations	1.0	0.834806
identification	GeneRIF Biological Term Annotations	1.0	null
caudal zona incerta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07279
arrhythmia	HPO Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.09818
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.70865
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.893
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.912426
limited	GeneRIF Biological Term Annotations	1.0	null
will	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32264
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	GO Molecular Function Annotations 2015	1.0	null
purine ribonucleoside triphosphate metabolic process	GO Biological Process Annotations 2023	1.0	null
decreased cholesterol level	MPO Gene-Phenotype Associations	1.0	null
abnormal circulating amino acid level	MPO Gene-Phenotype Associations	1.0	null
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78776
A204	BioGPS Cell Line Gene Expression Profiles	1.0	0.915343
virusmediated	GeneRIF Biological Term Annotations	1.0	null
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306444
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5397
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32301
founder	GeneRIF Biological Term Annotations	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42641
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
ZR75_1	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
ion binding	GO Molecular Function Annotations 2015	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.828897
BRD-K61726189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57864
organelle	GO Cellular Component Annotations 2015	1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55059
cutis laxa	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04335
Pseudoxanthoma elasticum	ClinVar Gene-Phenotype Associations 2025	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.779401
BRD-K14098658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20561
modifier	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88841
renal insufficiency	HPO Gene-Disease Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26549
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
pseudogenes	GeneRIF Biological Term Annotations	1.0	null
GSE217201_1_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
determinants	GeneRIF Biological Term Annotations	1.0	null
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66295
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-Embryo-Hatchling_1272_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165435
myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449886
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922702
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215341
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.36082
NCI-H1650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Status Epilepticus	CTD Gene-Disease Associations	1.0	1.22916
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
abnormality of the abdominal organs	HPO Gene-Disease Associations	1.0	null
abnormal sterol level	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
calcinosis; pseudoxanthoma elasticum	GAD Gene-Disease Associations	1.0	null
glial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Multidrug resistance-associated protein 6	InterPro Predicted Protein Domain Annotations	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877176
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.138
BRD-K03829970_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17357
beclometasone-3001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11906
BRD-K28596345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14984
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14399
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32268
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.859124
Skin Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
TRMT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1497
OV-90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HMGCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62507
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47457
Diffuse idiopathic skeletal hyperostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
cardiovascular system phenotype	MPO Gene-Phenotype Associations	1.0	null
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73701
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.996606
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85929
hsa-miR-873	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32156
Peripheral Nervous System Diseases	CTD Gene-Disease Associations	1.0	2.88009
SIN3A	ENCODE Transcription Factor Targets	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
widespread	GeneRIF Biological Term Annotations	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92253
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5746-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
juxtacommissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03645
response to stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925312
Lung squamous cell carcinoma_LUSC_TCGA-85-8584-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.214366
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KB-3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
BRD-K25330450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18599
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
italian	GeneRIF Biological Term Annotations	1.0	null
abnormality of the coronary arteries	HPO Gene-Disease Associations	1.0	null
GTEX-X4LF-0526-SM-3NMB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19714
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08647
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26232
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47349
GTEX-SE5C-1526-SM-4BRWU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960674
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterior parietal association areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48536
importance	GeneRIF Biological Term Annotations	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11722
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82815
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32336
hsa-miR-2355-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin rash	HPO Gene-Disease Associations	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.932337
Ankylosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.886
BRD-K94401439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83181
2-iodomelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96806
Autosomal recessive inherited pseudoxanthoma elasticum	ClinVar Gene-Phenotype Associations 2025	1.0	null
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18554
AKR1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28876
estradiol_homo sapiens_gpl571_gds4052	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cutis laxa	ClinVar Gene-Phenotype Associations 2025	1.0	null
hypothyroidism	HPO Gene-Disease Associations	1.0	null
Perturb_15534_KD_YAP1/WWTR1_SRP365715	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.46514
Congenital hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29502
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36736
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28233
rolitetracycline-3031	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
spectinomycin-2987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03297
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.61246
familial	GeneRIF Biological Term Annotations	1.0	null
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851124
Supramolecular polymer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.44
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.687891
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65547
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cefazolin-7385	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LY-294002-1074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S7-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-647	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
associate	GeneRIF Biological Term Annotations	1.0	null
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.05498
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ionomycin-882	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1715
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22297
abnormality of the myocardium	HPO Gene-Disease Associations	1.0	null
homozygous	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.12985
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
EFO-27	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.27456
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K53665750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70752
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rif1_KD_GDS4943_242_mouse_J1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06993
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.25838
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7488531-13287_2020_1914_MOESM10_ESM.xlsx-HNF4A_regulated_DEGs_750-Unnamed_1_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Supramolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.428
Artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.273
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02969
Medial Calcification Of Large Arteries	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_1078_OE_ZBED2_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50579
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Postural Instability	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_12107_KD_CCND1_SRP244245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.37581
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	2.25924
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
tyrphostin AG-1478-1141	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91507
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38549
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253553
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dactinomycin	HMDB Metabolites of Enzymes	1.0	null
lat1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
TC-71	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anemia	CTD Gene-Disease Associations	1.0	1.46093
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
those	GeneRIF Biological Term Annotations	1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932696
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09569
SARS-CoV_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.25002
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.347
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861063
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83641
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
assembly	GeneRIF Biological Term Annotations	1.0	null
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94487
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2517
calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.218374
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986594
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49424866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05706
activator	GeneRIF Biological Term Annotations	1.0	null
mode of inheritance	HPO Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.543
duplication	GeneRIF Biological Term Annotations	1.0	null
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.357814
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26009
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66651
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.295739
BRD-K91282650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62291
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30975
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92594
GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0026
valproic acid-2674	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
determinant	GeneRIF Biological Term Annotations	1.0	null
some	GeneRIF Biological Term Annotations	1.0	null
Increased Tendency To Bruise	DisGeNET Gene-Phenotype Associations	1.0	null
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.07433
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09655230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64049
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84077642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18472
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835111
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845733
GSE207301,GSE207303_0_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20306
Acute Myeloid Leukemia_LAML_TCGA-AB-2842-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lossoffunction	GeneRIF Biological Term Annotations	1.0	null
calcified skin	MPO Gene-Phenotype Associations	1.0	null
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28268
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.557263
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65J-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24937
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
ischemic	GeneRIF Biological Term Annotations	1.0	null
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42091
VMRCRCW	CCLE Cell Line Gene Expression Profiles	1.0	1.38209
Hemoglobin A, Glycosylated	dbGAP Gene-Trait Associations	1.0	0.093314
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43737
BRD-A39646320_H7270_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28562
Hypertrophy	CTD Gene-Disease Associations	1.0	2.07672
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.94015
coronary disease; coronary heart disease; inflammation; insulin resistance	GAD Gene-Disease Associations	1.0	null
GSE62843,GSE64370_0_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Neurologic Manifestations	CTD Gene-Disease Associations	1.0	1.21823
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
Posterior parietal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55372
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72805
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04577
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.75836
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypolipoproteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.932
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25561
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09862
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cutaneous Plaque	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Pelvic Organ Prolapse	DisGeNET Gene-Disease Associations	1.0	null
DOCETAXEL ANHYDROUS	DGIdb Drug Targets 2026	1.0	0.235253
Pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48391
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051992
BRD-K85985071_E3380_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dermal	GeneRIF Biological Term Annotations	1.0	null
ZR-75-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	2.02334
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07042
Vertebra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
angina pectoris	HPO Gene-Disease Associations	1.0	null
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
medial arterial calcification	HPO Gene-Disease Associations	1.0	null
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851064
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22688
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.690584
abnormal immunoglobulin level	GWASdb SNP-Phenotype Associations	1.0	0.882984
GSE62843,GSE64370_0_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
studies	GeneRIF Biological Term Annotations	1.0	null
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42605
abnormality of cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.326976
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20093
PMC12119775-13402_2024_1033_MOESM1_ESM.pdf-15-KLF6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00201
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12121
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.887819
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948322
USH1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9584
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cancer stem cell_Lymph_Human	CellMarker Gene-Cell Type Associations	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.70553
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37815
PMC10164164-41598_2023_34435_MOESM2_ESM.xlsx-FSK_CIC_KO_cp_to_CTL-gene_name_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3123
beryllium fluoride	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.142302
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.042
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87951090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17075
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Drusen	DisGeNET Gene-Disease Associations	1.0	null
diencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04815
Hepatitis, Autoimmune_Hepatic Tissue_GSE867	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.18911
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal external genitalia	GWASdb SNP-Phenotype Associations	1.0	0.248404
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13574
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37016
central subpallium (classic basal ganglia)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33791
atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162109
betamethasone-6728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44831
hsa-miR-4474-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
now	GeneRIF Biological Term Annotations	1.0	null
BRD-K89394474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03014
OVCAR5	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_8351_KD_TJP2_SRP306934	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.3988
Disease Progression	CTD Gene-Disease Associations	1.0	2.88009
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57528
BRD-K49712247_NCGC00167098-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.310367
PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
plasma lipoproteins	GAD Gene-Disease Associations	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
Tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.91
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23509
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22534
carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064203
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939946
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
Nephritis, Interstitial	CTD Gene-Disease Associations	1.0	1.41424
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.339
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
finds	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18967
preventing	GeneRIF Biological Term Annotations	1.0	null
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K54115231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5857
plag1	GeneRIF Biological Term Annotations	1.0	null
organic anion transport	GO Biological Process Annotations 2023	1.0	null
similar	GeneRIF Biological Term Annotations	1.0	null
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
5637	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.99751
carmustine-6888	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14373
Hemolysis	CTD Gene-Disease Associations	1.0	1.21823
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.780954
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11572
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.83207
clinical	GeneRIF Biological Term Annotations	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	3.18683
retinal hemorrhage	HPO Gene-Disease Associations	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056901
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858249
Beta Thalassemia	DisGeNET Gene-Disease Associations	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90562751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04384
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851264
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Supravalvular aortic stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5871
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68623
Hydrogenosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
Pain	CTD Gene-Disease Associations	1.0	1.70595
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4028
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6563
profile	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826963
ITGA7_OE_GDS3209_142_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60647
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0371
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of b cells	GWASdb SNP-Phenotype Associations	1.0	0.40409
abnormal posterior eye segment morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K13672060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51604
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE62843,GSE64371_4_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
strong	GeneRIF Biological Term Annotations	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4525	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
decreased susceptibility to dystrophic cardiac calcinosis	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K06157545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58953
BRD-K64890080_BI-2536_HT29_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Osteosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24832
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.94211
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.89153
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.88516
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3427
Choroidal Neovascularization	DisGeNET Gene-Phenotype Associations	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.841
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
adenyl ribonucleotide binding	GO Molecular Function Annotations 2023	1.0	null
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931928
EW-7	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.37583
PMC7602614__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.93383
Meningomyelocele	DisGeNET Gene-Disease Associations	1.0	null
Perturb_13306_KO_Hnf4a/Cdx2_SRP049189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.7113
Perturb_10232_KO_RN7SK_SRP201495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.3538
fludrocortisone-281	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K28296557_Akt inhibitor IV_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal Bruch membrane morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K37165790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16881
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856877
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20249
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98994
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865772
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40738845_BMS-777607_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ecoli	GeneRIF Biological Term Annotations	1.0	null
Central Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.16799
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
hsa-miR-676	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
visual loss	HPO Gene-Disease Associations	1.0	null
abnormal amino acid level	MPO Gene-Phenotype Associations	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7421
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90295
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.82611
atpase activity, coupled	GO Molecular Function Annotations 2015	1.0	null
A_CA_04_2009_4dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.83055
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19988
DAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04209
A549_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212109
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58403
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999087
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994542
myosmine-3737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
calcein AM	CTD Gene-Chemical Interactions	1.0	null
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
BECKER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55343
BRD-K28811650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33216
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Pseudoxanthoma Elasticum	DisGeNET Gene-Disease Associations	1.0	null
BRD-K17582293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11884
BRD-K51779559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23004
Cisplatin	DrugBank Drug Targets	1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.952
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09122
developmental	GAD High Level Gene-Disease Associations	1.0	0.298214
etiology	GeneRIF Biological Term Annotations	1.0	null
Visual Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
Lithocholic Acid	CTD Gene-Chemical Interactions	1.0	null
rickets	HPO Gene-Disease Associations	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
icosanoid transport	GO Biological Process Annotations 2025	1.0	null
BRD-K96839404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63493
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-ethylmaleimide-S-glutathione	CTD Gene-Chemical Interactions	1.0	null
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.42674
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ6-0926-SM-3P5ZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883126
Hepatitis C infection_Hepatocyte_GSE2067	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.44134
Hepatic Encephalopathy	CTD Gene-Disease Associations	1.0	1.39702
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.062104
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05295
arteriosclerosis	HPO Gene-Disease Associations	1.0	null
hsa-miR-122	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881793
axis	GeneRIF Biological Term Annotations	1.0	null
icSARS CoV_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.2208
ppi	GeneRIF Biological Term Annotations	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44317
occipital cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02086
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.922
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914299
BRD-K93460493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0606
control	GeneRIF Biological Term Annotations	1.0	null
abnormality of connective tissue	HPO Gene-Disease Associations	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-656	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Lung adenocarcinoma_LUAD_TCGA-44-A47B-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17841
Arterial blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.0
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37595
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79263
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14738
bezafibrate-6653	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sensory perception of light stimulus	GO Biological Process Annotations 2015	1.0	null
Cardiovascular Abnormalities	HuGE Navigator Gene-Phenotype Associations	1.0	null
PMC6084392-oncotarget-09-30253-s006.xls-geneset1-TF-miRNA-net-NRL_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
chorioretinal abnormality	HPO Gene-Disease Associations	1.0	null
Hodgkin Disease	DisGeNET Gene-Disease Associations	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.446862
GRHL2-25758223-PLACENTA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
quinisocaine-4207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
DNAAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68526
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975321
hsa-miR-766	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
accelerated atherosclerosis	HPO Gene-Disease Associations	1.0	null
hematologic cancer	GWASdb SNP-Disease Associations	1.0	1.00407
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9157
A101D	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20053
Proteinuria	CTD Gene-Disease Associations	1.0	1.86027
Perturb_15574_KD_NUSAP1_SRP074246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.7971
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
layer 6 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2119
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46D-01A-21R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89114
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06132
Talus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.367
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal circulating lipid level	MPO Gene-Phenotype Associations	1.0	null
azaperone-6151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07737
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
abnormal vibrissa follicle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.872167
endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104947
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897115
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
thickened nuchal skin fold	HPO Gene-Disease Associations	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20799
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17216
Lung adenocarcinoma_LUAD_TCGA-75-6212-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.58787
heterozygosity	GeneRIF Biological Term Annotations	1.0	null
Tachycardia, Ventricular	CTD Gene-Disease Associations	1.0	1.36447
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892829
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-NR3C1_partners-NR3C1_known_protein_partners_according_to_BioGrid_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Hydronephrosis	DisGeNET Gene-Disease Associations	1.0	null
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
BRD-K18787491_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11898
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00501
VPS72	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00396956
PMC8617980__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0443
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01024
Hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.132
high-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.107
MsbA transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60257
PMC4661210__F3	PFOCR Pathway Figure Associations 2023	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.00207
BRD-K76115264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30131
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00543
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60252
BRD-K67022703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01943
hsa-miR-588	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68705041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34862
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02854
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06958
ABL1_knockdown_100_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.70741
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	2.15316
like	GeneRIF Biological Term Annotations	1.0	null
modify	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14354
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44845
A549_Alvespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012194
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
Intracellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.799
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26117
BRD-K12359218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05812
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825102
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
hyperinsulinemic hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.394863
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07821
retinal diseases	GAD Gene-Disease Associations	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ag	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitral valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
BRD-K85951787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24809
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7783
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
20860821-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
cyproterone-6806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42849
CCP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35298
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
functional abnormality of the gastrointestinal tract	HPO Gene-Disease Associations	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
atpase activity, coupled to transmembrane movement of substances	GO Molecular Function Annotations 2015	1.0	null
abnormality of bone mineral density	HPO Gene-Disease Associations	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ski complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
abdominal tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.286519
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18163
BRD-K03937692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07559
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35575
CISD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88609
BL1797 (BCL11A)	NURSA Protein Complexes	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00774
coronary artery disease	HPO Gene-Disease Associations	1.0	null
Pseudoxanthoma elasticum	ClinVar Gene-Phenotype Associations	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92431275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7396
AKT1_knockdown_141_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.52126
Caffey disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
Abnormality Of The Eye	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02131
Chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
Dubin-Johnson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.483
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7879
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colistin-2491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO849	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76844
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.368176
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21125
BRD-K05248013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1444
BRD-K60123410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09205
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain small vessel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
miconazole-4960	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.293278
ABC transporter-like	InterPro Predicted Protein Domain Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-24	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.1981
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A31962514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73085
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17605
transcripts	GeneRIF Biological Term Annotations	1.0	null
Gastrointestinal Hemorrhage	CTD Gene-Disease Associations	1.0	1.11741
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23627
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
Autosomal recessive hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.245
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
BRD-K69241192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.80915
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
hepatocytes	GeneRIF Biological Term Annotations	1.0	null
Perturb_17248_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.47364
GSE157049,GSE157051_6_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76401790_JNK-IN-5A_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02854
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886583
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
calcium ion homeostasis	GO Biological Process Annotations 2025	1.0	null
Seizures	CTD Gene-Disease Associations	1.0	1.67462
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29338
BRD-K15025317_Bay 11-7821_AGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
used	GeneRIF Biological Term Annotations	1.0	null
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09701
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12815
many	GeneRIF Biological Term Annotations	1.0	null
BRD-A58955223_L-sulforophane_NCIH1836_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cataract	CTD Gene-Disease Associations	1.0	1.05349
retinopathy	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.4827
Perturb_10921_KO_Flcn_SRP278840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.80432
intermittent claudication	HPO Gene-Disease Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
risk	GeneRIF Biological Term Annotations	1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08819
BRD-K50830147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81567
Prostate adenocarcinoma_PRAD_TCGA-EJ-7218-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70886325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00197
variation	GeneRIF Biological Term Annotations	1.0	null
BRD-K39664334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32569
Aortic Aneurysm	DisGeNET Gene-Disease Associations	1.0	null
FOXA2	ChEA Transcription Factor Targets	1.0	null
BRD-K27137352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22393
BRD-K10459843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20065
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
response to chemical	GO Biological Process Annotations 2015	1.0	null
HMOX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514106
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501182
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
abnormality of the macula	HPO Gene-Disease Associations	1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A28105619_curcubitacin I_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
genetic	GeneRIF Biological Term Annotations	1.0	null
Elastic fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.237
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
circular	GeneRIF Biological Term Annotations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Pulmonary Edema	CTD Gene-Disease Associations	1.0	1.35792
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33112
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30062
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Factor X deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
BRD-K19962165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02641
nf96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.2901
SHP-77	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.24687
MAP3K14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25752
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26649
layer 6 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93785
HNF4A	ENCODE Transcription Factor Targets	1.0	null
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26398
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
BRD-K50240676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50303
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.825858
intracranial arterial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.113692
BRD-K20912596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08529
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957455
BRD-K08799663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45898
ZBTB33_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-1084-6125	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K03262163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02675
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediterranean	GeneRIF Biological Term Annotations	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.987159
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.17514
classic	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K62466453_NCGC00182388-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.89058
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61952
hsa-miR-548ai	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08162
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16059
BRD-K35978846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36418
disturbance	GeneRIF Biological Term Annotations	1.0	null
ADAMTSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67526
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of PCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29502
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333763
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97362312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01224
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00603
BRD-K79619334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16338
Alopecia	CTD Gene-Disease Associations	1.0	1.27101
SQLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02354
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.69026
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04917
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48723
Melnick-Needles syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27408
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65867
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31729
CADASIL	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Subcutaneous Nodule	DisGeNET Gene-Phenotype Associations	1.0	null
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41929
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
DLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93007
RNF139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55035
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77003
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11331
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64494
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.740515
BRD-K88156935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30349
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
had	GeneRIF Biological Term Annotations	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.74721
BRD-K14203360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27781
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101239_3_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hesperidin-6714	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_9239_KD|OE_ENL|ENL_SRP074134	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.55398
abnormal lipid homeostasis	MPO Gene-Phenotype Associations	1.0	null
Parathyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
t30-blood-rna_male_2w	MoTrPAC Rat Endurance Exercise Training	-1.0	-1.69843
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1068
glia	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
african	GeneRIF Biological Term Annotations	1.0	null
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
diseases	GeneRIF Biological Term Annotations	1.0	null
succinylcholine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17161
PDCD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14861
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.519
Insulin Resistance	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipito-temporal gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871515
pseudoxanthoma elasticum	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	4.16194
Fetal Diseases	CTD Gene-Disease Associations	1.0	1.16269
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
schoolaged	GeneRIF Biological Term Annotations	1.0	null
Hepatic artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0606
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14482
fluorescence	GeneRIF Biological Term Annotations	1.0	null
HT55	CCLE Cell Line Gene Expression Profiles	1.0	1.49581
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18092
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10575
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166133
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
Fibrosis	CTD Gene-Disease Associations	1.0	2.15205
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
weakness due to upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
GSE80182_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_9599_KO_Csnk1a1_ERP003394	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K09149805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93454
BRD-K57472585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35934
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32558
NCIH2347	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4729
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.13365
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.93433
Marfan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
Thyroid Diseases	CTD Gene-Disease Associations	1.0	1.14336
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04419
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48536
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.44871
calcified intraocular region	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75649446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05637
Aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
Vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.579
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057516
BRD-K49745983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3188
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30759
ETS1	ENCODE Transcription Factor Targets	1.0	null
doxazosin-3024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K97086564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36995
inflammatory abnormality of the skin	HPO Gene-Disease Associations	1.0	null
Williams-Beuren syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
Prostate adenocarcinoma_PRAD_TCGA-EJ-7317-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular calcification	HPO Gene-Disease Associations	1.0	null
abnormality of the thyroid gland	HPO Gene-Disease Associations	1.0	null
Rhabdomyosarcoma	CTD Gene-Disease Associations	1.0	1.05237
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91977
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
HCV JFH-1_18Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.57602
GSE125007,GSE125008_5_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A704	GDSC Cell Line Gene Expression Profiles	1.0	1.46959
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11762
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Zellweger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29365
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824915
hsa-miR-581	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K19166598_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K13922961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58078
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.159461
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2025
Celiac Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-A50737080_CGK-733_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981874
angioid streaks of the retina	HPO Gene-Disease Associations	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.184
GTEX-Q2AH-0926-SM-48TZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08199
Endocardial fibroelastosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.20262
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29681
Fetal Death	CTD Gene-Disease Associations	1.0	1.51531
Systemic Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL_wt_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35034
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38037
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
demonstrates	GeneRIF Biological Term Annotations	1.0	null
DU-4475	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.42014
Superficial Ulcer	DisGeNET Gene-Disease Associations	1.0	null
reservoir	GeneRIF Biological Term Annotations	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1683
lateral part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37016
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77652
BRD-A18411371_2-[(chloroacetyl)(3-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.054
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325335
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K35945596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02733
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896667
Ewings Sarcoma	DisGeNET Gene-Disease Associations	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932794
GTF3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45707
Primary motor area, Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55372
BRD-K08109215_I-BET_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K52956006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87817
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87007
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
collagen disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.089813
unanticipated	GeneRIF Biological Term Annotations	1.0	null
unknown	GeneRIF Biological Term Annotations	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.098
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.90375
loss	GeneRIF Biological Term Annotations	1.0	null
TERT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65705
Vascular disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920811
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.82115
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Hemiplegia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K30510226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5659
gossypol-6058	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49908
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58841
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03241
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A16760970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08878
estradiol_homo sapiens_gpl1225_gse1486	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059401
GTEX-XV7Q-1726-SM-4BRUU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969248
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
BRD-K80786583_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.337808
BRD-K50114736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1286
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Inappropriate ADH Syndrome	CTD Gene-Disease Associations	1.0	1.05685
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15383
BRD-K91879432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32226
Paresthesia	CTD Gene-Disease Associations	1.0	1.6891
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885135
BRD-K49865102_PD-0325901_HEPG2_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2041
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68174511_torin-2_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
BRD-K26024910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08327
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35037
decreased circulating hdl cholesterol level	MPO Gene-Phenotype Associations	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
hnf4a_21852396_wao9_lof_human_gpl570_gds3926	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.72724
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979437
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.36543
H3-3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60324
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08535
BRD-K64135153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5035
DIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36485
UM-SCC-22A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873577
BRD-A39996500_radicicol_MCF10A_3_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
calcified retina	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.471089
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
Chromosome Duplication	HuGE Navigator Gene-Phenotype Associations	1.0	null
WIF-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07002
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.063859
endoplasmic	GeneRIF Biological Term Annotations	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.072303
trimethadione-4086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045142
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3837
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
cloxacillin-7483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
normal	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A456-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
PMC6119347__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
calcinosis	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99112
gastrointestinal hemorrhage	HPO Gene-Disease Associations	1.0	null
there	GeneRIF Biological Term Annotations	1.0	null
BRD-K90874005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43746
hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063028
Hyperplasia	CTD Gene-Disease Associations	1.0	2.31364
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09976
striatum (corpus striatum)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21351
BRD-K38510068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58733
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HF-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30839
Manganese	CTD Gene-Chemical Interactions	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35881
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26005
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.03605
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	2.11092
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00491
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
lovastatin-4978	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K45984211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53312
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53409
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
elasticum	GeneRIF Biological Term Annotations	1.0	null
BRD-U64521890_XMD16-144_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
product	GeneRIF Biological Term Annotations	1.0	null
lateral part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02854
BRD-K67835515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18826
BRD-K08247496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04662
PHRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15135
cyproheptadine-5340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.0921
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341863
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
calcified artery	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854151
Chronic myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
injuries	GeneRIF Biological Term Annotations	1.0	null
Perturb_5734_KO_Gpr124_SRP064844	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.71856
mdck cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221445
children	GeneRIF Biological Term Annotations	1.0	null
GSE252988_0_v_1_lefamulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165001
BRD-K13849122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4805
USF1	ENCODE Transcription Factor Targets	1.0	null
brain microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263327
microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173647
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73789395_ZM 336372_A673_6.0_h_102.71_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961679
BRD-K61753872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36675
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23502
locus	GeneRIF Biological Term Annotations	1.0	null
CSE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80969
PMC10164164-41598_2023_34435_MOESM2_ESM.xlsx-FSK_CIC_KO_cp_to_CTL-gene_id_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6428_KD_ADAR1_SRP009659	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Hematologic Diseases	CTD Gene-Disease Associations	1.0	1.29471
skin_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.870289
coronary artery calcification	HPO Gene-Disease Associations	1.0	null
Hepatitis C	DisGeNET Gene-Disease Associations	1.0	null
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82251
premature	GeneRIF Biological Term Annotations	1.0	null
Hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85479
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.574
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03074
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11554977-40199_2024_523_MOESM2_ESM.xlsx-Sheet1-Supplement_2_Metformin_Drug_Sensitivity_and_Damaging_Mutation_by_using_PRISM_Repurposing_Primary_Screen_and_Damaging_Mutation_in_DepMap_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949587
ASPC1	CCLE Cell Line Gene Expression Profiles	1.0	1.66266
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13134
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.732
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99873441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32324
BRD-K07870648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23535
abnormal ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
Hyperostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.876421
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disorders of transmembrane transporters	Reactome Pathways 2024	1.0	null
Adenosine Triphosphate	CTD Gene-Chemical Interactions	1.0	null
RXRA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396844
TK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Psychomotor Disorders	CTD Gene-Disease Associations	1.0	1.12151
Teniposide	DrugBank Drug Targets	1.0	null
syrosingopine-1761	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39706
myocardial	GeneRIF Biological Term Annotations	1.0	null
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37493
Abdominal Pain	CTD Gene-Disease Associations	1.0	1.52287
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889421
PANC0403	CCLE Cell Line Gene CNV Profiles	1.0	1.39838
BRD-K49865102_PD-0325901_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911066
BRD-K10325583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37697
BRD-K39649723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76161
testicular neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.729372
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.118228
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99921
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06696
BRD-K35451051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18425
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72420232_WZ-4002_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054164
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44346
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16966
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.814126
region	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80439500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39369
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00196
organization	GeneRIF Biological Term Annotations	1.0	null
Gronblad-Strandberg Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K99116119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02389
Linear Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95900761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26056
basolateral plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18143
ATP transport	GO Biological Process Annotations 2025	1.0	null
vascular calcification	HPO Gene-Disease Associations	1.0	null
ATP metabolic process	GO Biological Process Annotations 2025	1.0	null
hyperpigmentation of the skin	HPO Gene-Disease Associations	1.0	null
denatonium benzoate-5061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBTB33_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35219
KLHL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
Pancreatitis	CTD Gene-Disease Associations	1.0	1.2208
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08641
Daunorubicin	HMDB Metabolites of Enzymes	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88157
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12157
Perturb_15800_KD_INTS13_SRP271267	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.12293
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0882
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32601
lack of skin elasticity	HPO Gene-Disease Associations	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
fibers	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892793
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16071
BRD-K77814566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27482
BL3032 (ERBB2)	NURSA Protein Complexes	1.0	null
mantle zone of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28904
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72678
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
BRD-K41895714_AS-605240_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
backgrounds	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4497_KO_Hnf4a/Hnf4g_SRP139365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892109
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
missense	GeneRIF Biological Term Annotations	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12486367-Supplementary_Data2.pdf-371-YBX1_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844168
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.914862
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74848
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921786
BRD-K23637241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19893
BRD-K64890080_BI-2536_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of the cerebrum	HPO Gene-Disease Associations	1.0	null
inhibits	GeneRIF Biological Term Annotations	1.0	null
SODIUM CHLORIDE	DGIdb Drug Targets 2026	1.0	0.756171
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.713
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916392
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6712
Conjugated Hyperbilirubinemia	DisGeNET Gene-Disease Associations	1.0	null
Calcification Of Coronary Artery	DisGeNET Gene-Phenotype Associations	1.0	null
Albuminuria	CTD Gene-Disease Associations	1.0	1.06734
extrapulmonary tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.127763
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
manifestations	GeneRIF Biological Term Annotations	1.0	null
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
Arterial Calcification	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
Infection by Yersinia enterocolitica_macrophage_GSE2973	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.04304
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899979
Idiopathic Arterial Calcification Of Infancy	DisGeNET Gene-Disease Associations	1.0	null
BRD-K83185986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28636
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08156
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rise	GeneRIF Biological Term Annotations	1.0	null
CRYBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00492
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881529
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16167
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.60132
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62964
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72667
Carotid atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05943
BRD-K13211285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09487
mitral valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.263722
Movement Disorders	CTD Gene-Disease Associations	1.0	1.31416
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64084
BRD-K09951645_dabrafenib_HEPG2_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24007
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49843
huh-7	BioGPS Cell Line Gene Expression Profiles	1.0	1.34341
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
membrane	GO Cellular Component Annotations 2015	1.0	null
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Chromosome passenger complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.031
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99463
ovarian surface epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.364139
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49808
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
Siphon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82731
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.67269
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EWSR1_KD_GDS4962_469_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Glycosuria	CTD Gene-Disease Associations	1.0	1.28827
abnormal bone structure	HPO Gene-Disease Associations	1.0	null
Combined deficiency of vitamin K-dependent clotting factors 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.18
SKRC20	CCLE Cell Line Gene Expression Profiles	1.0	1.80042
BRD-K75672292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13024
CHRNB4_Deficiency_GDS2309_714_mouse_Brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
embryoday9.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
Arterial Calcification Of Infancy	DisGeNET Gene-Disease Associations	1.0	null
Vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899234
BRD-K90138084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2617
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
essential	GeneRIF Biological Term Annotations	1.0	null
Byzanthine Arch Palate	DisGeNET Gene-Disease Associations	1.0	null
seen	GeneRIF Biological Term Annotations	1.0	null
BRD-K59131688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5738
GSE152734,GSE152735_1_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intracranial Hypertension	CTD Gene-Disease Associations	1.0	1.13895
Body Height	DisGeNET Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5942-01A-21R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01217
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73062
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923032
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2563
Lymphatic Diseases	CTD Gene-Disease Associations	1.0	1.06406
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.41393
NCIH1184	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53862
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.905581
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
renovascular hypertension	HPO Gene-Disease Associations	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
vitamin k deficiency hemorrhagic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160761
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27878
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35213
naftopidil-4193	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hyperextensible skin	HPO Gene-Disease Associations	1.0	null
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65228
BRD-K45916030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37574
dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05896
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.066779
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72667
prosomere 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14751
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
BRD-K98474331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16824
localization	GeneRIF Biological Term Annotations	1.0	null
BRD-K31977946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01983
familial mediterranean fever	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.287235
Restrictive Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
BRD-K10882151_BO2 (inhibits RAD51)_HEPG2_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K57179821_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
all	HPO Gene-Disease Associations	1.0	null
Calcification Of Joints And Arteries	DisGeNET Gene-Disease Associations	1.0	null
BRD-K46056750_AZD-7762_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K80724972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07542
Daunorubicin	DrugBank Drug Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07668
circulation	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.07776
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76335
baclofen-6313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
C3A	CCLE Cell Line Gene Expression Profiles	1.0	2.02321
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55902
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.77511
Ischemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K21620541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41436
structural	GeneRIF Biological Term Annotations	1.0	null
basolateral plasma membrane	GO Cellular Component Annotations 2025	1.0	null
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32875
G-402	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.8551
Pseudotumor Cerebri	CTD Gene-Disease Associations	1.0	1.19966
Lung adenocarcinoma_LUAD_TCGA-55-7573-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38512
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10095
atherosclerosis	HPO Gene-Disease Associations	1.0	null
RF-48	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.38687
Prostate adenocarcinoma_PRAD_TCGA-G9-7521-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pleural Effusion	CTD Gene-Disease Associations	1.0	1.22339
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00257
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRO-AP2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.09031
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
dnase	GeneRIF Biological Term Annotations	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29338
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63454
Perturb_3697_KD_FTO_SRP226373	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.05789
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.931678
BRD-K90382497_GW-843682X_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39851
Chromosome Deletion	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65489
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Teniposide	HMDB Metabolites of Enzymes	1.0	null
ifosfamide-3485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K58087285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01564
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.862059
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
retinal	GeneRIF Biological Term Annotations	1.0	null
abnormality of the uvea	HPO Gene-Disease Associations	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04419
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.246442
second	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4633-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37168
correction	GeneRIF Biological Term Annotations	1.0	null
NCIH2023	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61362
DSH1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56988
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	GeneRIF Biological Term Annotations	1.0	null
Progressive familial intrahepatic cholestasis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.92725
bp94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11909
homeostasis	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8397-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retinal deposits	MPO Gene-Phenotype Associations	1.0	null
Cef cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
16491124-Table1	GeneSigDB Published Gene Signatures	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
BRD-U70626184_BI-2536_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2373	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.32627
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31531
GSE222445_2_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Aortic valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057978
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32016
PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.837
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
large artery calcification	HPO Gene-Disease Associations	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hepa-RG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
ATR_knockdown_140_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.07854
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	2.06768
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
Basal plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
their	GeneRIF Biological Term Annotations	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03334
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.334
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.927548
BRD-K27028848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57047
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03344897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69107
Microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.262
give	GeneRIF Biological Term Annotations	1.0	null
abnormal pyramidal signs	HPO Gene-Disease Associations	1.0	null
trichostatin A-3058	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K41895714_AS-605240_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hypertension	HPO Gene-Disease Associations	1.0	null
fibre	GeneRIF Biological Term Annotations	1.0	null
BRD-K73839552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44924
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
BRD-K13662825_dinaciclib_HCC515_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22726
biosynthesis	GeneRIF Biological Term Annotations	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17925
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48102
Hallucinations	CTD Gene-Disease Associations	1.0	1.10907
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	1.4122
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12253
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57014
variety	GeneRIF Biological Term Annotations	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2041
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73654
Muscle Weakness	CTD Gene-Disease Associations	1.0	1.26236
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870719
KRAS.AMP.LUNG_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10725
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92162
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896596
Bile canaliculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
BAG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55515
pseudoxanthoma	GeneRIF Biological Term Annotations	1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29628221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03872
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14672
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74199
BRD-K72261386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33208
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ornidazole-5064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU761	CCLE Cell Line Gene Expression Profiles	1.0	1.65415
BRD-K72745710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49286
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2719
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the cerebral vasculature	HPO Gene-Disease Associations	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82786
ptc124	GeneRIF Biological Term Annotations	1.0	null
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30766
layer 5 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09377
Chondrogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
nephrocalcinosis	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21267
parietal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29502
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865462
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intermittent Claudication	DisGeNET Gene-Phenotype Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05598
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.217
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01601
single	GeneRIF Biological Term Annotations	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23011
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
proapoptotic	GeneRIF Biological Term Annotations	1.0	null
exon-exon junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.082606
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09467
Perturb_7963_OE_DKC1_SRP103222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.15501
BRD-K82130737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68229
LS-174T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.11747
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
isocarboxazid-7383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05124
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.07947
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92442
Leukopenia	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
proadifen-3446	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911497
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03629
cycle	GeneRIF Biological Term Annotations	1.0	null
increased circulating creatinine level	MPO Gene-Phenotype Associations	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-575	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
docetaxel	CTD Gene-Chemical Interactions	1.0	null
BRD-K76694128_DCC-2036_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
alar plate of p2 (alar thalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04419
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal joint morphology	HPO Gene-Disease Associations	1.0	null
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_24_ape-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23151
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22353
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Breast adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
Basal part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Arthralgia	CTD Gene-Disease Associations	1.0	1.02373
SLR23	CCLE Cell Line Gene CNV Profiles	1.0	1.8421
genital neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.276363
Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60828476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39459
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.065
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10514
levocabastine-2948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-2.49007
point	GeneRIF Biological Term Annotations	1.0	null
NCIH1435	CCLE Cell Line Gene Expression Profiles	1.0	1.3807
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00569
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.481648
nterminal	GeneRIF Biological Term Annotations	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
pentoxifylline-1444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64477
Tangier disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.089
pramocaine-2198	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84251
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K36725646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31531
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922411
abnormality of the neck	HPO Gene-Disease Associations	1.0	null
Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44428
recently	GeneRIF Biological Term Annotations	1.0	null
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44083
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1116	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
arteriovenous malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.233878
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0882
transport	GeneRIF Biological Term Annotations	1.0	null
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02998
atypical	GeneRIF Biological Term Annotations	1.0	null
Tunica externa vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.693499
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.074058
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01711
HEP3B217	CCLE Cell Line Gene Expression Profiles	1.0	1.73346
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17795
BRD-K53959060_Indirubin-3-oxime_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mitral stenosis	HPO Gene-Disease Associations	1.0	null
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96584
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902979
Endoplasmic reticulum quality control compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
Aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.014
RXRA	ENCODE Transcription Factor Targets	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
systemic	GeneRIF Biological Term Annotations	1.0	null
BRD-K17743125_belinostat_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edema	CTD Gene-Disease Associations	1.0	2.05695
abnormality of the gastrointestinal tract	HPO Gene-Disease Associations	1.0	null
Bradycardia	CTD Gene-Disease Associations	1.0	1.07518
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
Brain small vessel disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRE11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00562169
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43024
Pruritus	CTD Gene-Disease Associations	1.0	1.06116
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.53028
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.926696
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Neural arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
DNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80962
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890119
BRD-K76544773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03316
RCM1	CCLE Cell Line Gene Expression Profiles	1.0	2.00673
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0093
functions	GeneRIF Biological Term Annotations	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	2.0463
BRD-K64221857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.427
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46751
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
BRD-K16406336_METHYLENE BLUE_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Internal carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08459
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_24_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.836
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.337
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30374
PMC4661210__F3	PFOCR Pathway Figure Associations 2024	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04137
chenodeoxycholic acid-7433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of blood circulation	HPO Gene-Disease Associations	1.0	null
than	GeneRIF Biological Term Annotations	1.0	null
BRD-K28184331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31946
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43632
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
alterations	GeneRIF Biological Term Annotations	1.0	null
exudative vitreoretinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.332487
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09365
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929243
BRD-K16406336_METHYLENE BLUE_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
arterial endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218186
Multiple Tumors	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K60216304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29722
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15977
GATA1_G1E-ER4_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiomegaly	CTD Gene-Disease Associations	1.0	1.45989
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Abnormal Endocardium Morphology	DisGeNET Gene-Phenotype Associations	1.0	null
phenotype	GeneRIF Biological Term Annotations	1.0	null
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05324
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hypertension, Portal	CTD Gene-Disease Associations	1.0	1.04684
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
abnormality of the fundus	HPO Gene-Disease Associations	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arterial tortuosity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
abnormal snout skin morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K96023136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75411
Palatine uvula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.56755
Tunica media vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14556
relevance	GeneRIF Biological Term Annotations	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00501
UBB_KO_GDS3906_494_mouse_Testis -  21 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
hypertrophic cardiomyopathy	HPO Gene-Disease Associations	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05383
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09225
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4733-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19066
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828442
Telangiectasia	DisGeNET Gene-Phenotype Associations	1.0	null
chromosome	GeneRIF Biological Term Annotations	1.0	null
BRD-K96758498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25374
Stomach Diseases	CTD Gene-Disease Associations	1.0	1.16766
Glioblastoma	CTD Gene-Disease Associations	1.0	1.19672
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34221
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22953
myositis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.07524
TM9SF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18527
BRD-K83477969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10767
BRD-K46603043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92995
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68521
AsPC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.49862
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K90480740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36647
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.586828
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31263
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02892
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840031
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42417
BRD-K32520360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73725
GSE70499_3_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
flufenamic acid-5059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Premature Coronary Artery Atherosclerosis	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835111
BRD-K20437312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23088
PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91201
HIV Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28842
A1BG	Pathway Commons Protein-Protein Interactions	1.0	null
head and neck cancer	GWASdb SNP-Disease Associations	1.0	0.834806
BRD-K13301506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06969
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07917
JHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
highly	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.16207
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955934
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.38211
Cancellous bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38276
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55137
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04767
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78566
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46224
toxicity	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844474
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13245
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.92267
NCI/ADR-RES cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
carbarsone-3991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.916092
Perturb_17176_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12416
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39244
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04117
abnormality of the testis	GWASdb SNP-Phenotype Associations	1.0	0.345213
monoatomic cation homeostasis	GO Biological Process Annotations 2023	1.0	null
GSE81193_0_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.7237
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02504
autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
antiapoptotic	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5789-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13968264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49048
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular	GeneRIF Biological Term Annotations	1.0	null
Dyslipidemias	CTD Gene-Disease Associations	1.0	1.11116
metabolic syndrome	GAD Gene-Disease Associations	1.0	null
techniques	GeneRIF Biological Term Annotations	1.0	null
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.927621
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85544
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38391
Endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14955
BRD-K51087734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79996
showed	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-199b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Metamorphopsia	DisGeNET Gene-Phenotype Associations	1.0	null
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54369
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930505
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29879
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0002
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.169
Brn3a_KO_GDS1651_247_mouse_Embryonic (day 13.5) trigeminal ganglia - heterozygous	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23351
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05106
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72765
Progressive familial intrahepatic cholestasis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
Pseudoxanthoma elasticum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	4.0
BRD-K46056750_AZD-7762_HCC515_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18444
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Ldlr Mutation	DisGeNET Gene-Disease Associations	1.0	null
Perturb_324_KD_BCAP31_SRP320890	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.3353
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26294
Craniometaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20113
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEPARAN SULFATE	DGIdb Drug Targets 2026	1.0	1.7644
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fulfills	GeneRIF Biological Term Annotations	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.663
BRD-K35156336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33694
BRD-K40306365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33143
B3GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48293
artery	GeneRIF Biological Term Annotations	1.0	null
ggcx	GeneRIF Biological Term Annotations	1.0	null
GTEX-WHPG-0626-SM-3NMBD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992675
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906932
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
liver	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.7581
atpdependent	GeneRIF Biological Term Annotations	1.0	null
A-172 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.918206
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K69132276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33308
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K31614544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40477
Patterned macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
BRD-K67873600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22725
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.758
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.116216
KRBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03873
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.95597
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.13003
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
significant	GeneRIF Biological Term Annotations	1.0	null
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cobalt	CTD Gene-Chemical Interactions	1.0	null
abnormality of the choroid	HPO Gene-Disease Associations	1.0	null
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46029
PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BEL-7402 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
CHKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477188
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.11974
Hoxc13_OE_GDS1890_174_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859916
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Senescence_frontal cortex_GSE1572	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.68475
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994717
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LS-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFE2L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525781
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.923521
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6474
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97873
PMC11511846-42003_2024_7078_MOESM3_ESM.xlsx-ST18-Unnamed_19_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95438
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29569
dna	GeneRIF Biological Term Annotations	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76498
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20389
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
panniculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.231102
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61014
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86191271_Cytosporone B_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fenbufen-2308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chondrocalcinosis	HPO Gene-Disease Associations	1.0	null
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47018
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05103
Vitelliform macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08033
adenyl ribonucleotide binding	GO Molecular Function Annotations 2025	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00501
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUZC-1026-SM-4BOPY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845517
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37049
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924562
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03904
atpase activity, coupled to movement of substances	GO Molecular Function Annotations 2015	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59748
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GU-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mfe280	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
BRD-K54637865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09654
Parathyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54338
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74803
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Injuries	CTD Gene-Disease Associations	1.0	1.05793
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17137
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNCA_KO_GDS4153_442_mouse_Cerebellum - 6 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.28
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
calcified artery	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-4942-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60812542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84467
media	GeneRIF Biological Term Annotations	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.056844
BRD-K37846922_GR-207_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19226
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78035
Adrenoleukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
erbB-2_OE_GDS1925_164_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K60807536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51739
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18205
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957845
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.99859
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.30052
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21047
Aortic root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.163
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72086
Kidney Diseases	CTD Gene-Disease Associations	1.0	2.29427
supposes	GeneRIF Biological Term Annotations	1.0	null
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864136
Congestive Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abdominal	GeneRIF Biological Term Annotations	1.0	null
abnormality of the vasculature	HPO Gene-Disease Associations	1.0	null
BRD-K66985689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2975
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.9588
striae distensae	HPO Gene-Disease Associations	1.0	null
direct	GeneRIF Biological Term Annotations	1.0	null
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41574
BRD-K03816923_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fibromyalgia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.138564
main	GeneRIF Biological Term Annotations	1.0	null
delineation	GeneRIF Biological Term Annotations	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.63757
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04281
hsa-miR-1182	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
atp binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K16915521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47077
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-548g	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K09661167_OSSK_645683_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
BRD-K59670689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24037
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17672
Myocardial Infarction	HuGE Navigator Gene-Phenotype Associations	1.0	null
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.39016
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67848
Hereditary spastic paraplegia 64	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.763
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sulfasalazine-204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Medial septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00491
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46876
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	0.149968
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
IRF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08132
BRD-K55402144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2793
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04815
monorden-484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Papule	DisGeNET Gene-Phenotype Associations	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929754
Hyperparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20568
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72463
BRD-K03519778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47634
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70291
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.733
Prostate adenocarcinoma_PRAD_TCGA-EJ-5515-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
zaprinast-5349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95558
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884488
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891872
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52749
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849903
harbor	GeneRIF Biological Term Annotations	1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
purine ribonucleotide transport	GO Biological Process Annotations 2023	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
abnormality of adipose tissue	HPO Gene-Disease Associations	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Loeys-Dietz syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47926
Multiple myeloma (survival)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
BRD-K65725294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16513
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PH-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.841271
CORL311	CCLE Cell Line Gene Expression Profiles	-1.0	-2.24568
E2F1	ChEA Transcription Factor Targets	1.0	null
BRD-K19540840_saracatinib_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9421
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.47012
illustrate	GeneRIF Biological Term Annotations	1.0	null
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39385
abnormality of the posterior segment of the eye	HPO Gene-Disease Associations	1.0	null
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hyaline Body	DisGeNET Gene-Disease Associations	1.0	null
dermal fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.874862
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905758
Hypothyroidism	DisGeNET Gene-Disease Associations	1.0	null
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Glutathione	CTD Gene-Chemical Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886781
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877114
BRD-K42511168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28795
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.87126
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927023
Aortic dissection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
BRD-K98731749_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63858
Normophosphatemic familial tumoral calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
SLC18A3_KD_GDS4325_618_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23542
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-11A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912989
KB-C2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62122
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085629
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.861086
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.849536
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973595
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844707
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15795
coronary	GeneRIF Biological Term Annotations	1.0	null
Premature Occlusive Vascular Stenosis	DisGeNET Gene-Disease Associations	1.0	null
within	GeneRIF Biological Term Annotations	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.1136
TAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75414
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11809
atp	GeneRIF Biological Term Annotations	1.0	null
peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.300533
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99628
BRD-K35960502_NICLOSAMIDE_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835932
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31799
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
Osteogenesis imperfecta type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37687095_AZD-8330_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59922784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27657
Pons	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
Fatigue	CTD Gene-Disease Associations	1.0	1.15526
Fever	CTD Gene-Disease Associations	1.0	1.73639
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12014
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
Drug Eruptions	CTD Gene-Disease Associations	1.0	1.10907
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914299
macular degeneration	HPO Gene-Disease Associations	1.0	null
PMC7602614__F3	PFOCR Pathway Figure Associations 2024	1.0	null
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.559371
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.02869
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05639
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984433
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.02969
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980606
Pericardial Effusion	CTD Gene-Disease Associations	1.0	1.49736
Anteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18151
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33562
aneurysm	GeneRIF Biological Term Annotations	1.0	null
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07919
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K13094524_PFI-1_PC3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hyperextensible Skin	DisGeNET Gene-Phenotype Associations	1.0	null
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
BRD-K64317740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43638
determine	GeneRIF Biological Term Annotations	1.0	null
layer 5 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08535
clebopride-1292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81656074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08251
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10708
Autosomal recessive congenital ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34128
parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19389
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28522188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19231
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FL5.12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
japanese	GeneRIF Biological Term Annotations	1.0	null
Phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.896
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
abnormality of sharpey fibers	HPO Gene-Disease Associations	1.0	null
BRD-K67843691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34554
BRD-K69520171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90443
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40206
induction	GeneRIF Biological Term Annotations	1.0	null
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0082
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1245
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94947
BRD-K13859368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58469
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.17761
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1905
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11974
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.366
BRD-K31342827_GF-109203X_AGS_6.0_h_12.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6555
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25268
Hep-G2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.621
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38367
BRD-K79438478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35145
apical plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01283
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.987066
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.18439
Hypoparathyroidism	DisGeNET Gene-Disease Associations	1.0	null
mislocalization	GeneRIF Biological Term Annotations	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	2.18145
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06138
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086774
BRD-K89744662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22569
usual	GeneRIF Biological Term Annotations	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
ZFAND2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98342
Fatty Liver	CTD Gene-Disease Associations	1.0	2.28941
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.075001
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4788
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36255
LB647-SCLC	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.5935
Hyperphosphatemic familial tumoral calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
BRD-K08715020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97472
HEPG2	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
ATP binding	GO Molecular Function Annotations 2023	1.0	null
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56862
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65557
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37729
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2156
Pallidum, medial region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92676
Calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.398
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
atherosclerosis, coronary	GAD Gene-Disease Associations	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02855
abnormal optic choroid morphology	MPO Gene-Phenotype Associations	1.0	null
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12884
corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.128867
proinflammatory	GeneRIF Biological Term Annotations	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0882
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859114
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12985
aneurysm	HPO Gene-Disease Associations	1.0	null
Esophageal Neoplasms	CTD Gene-Disease Associations	1.0	1.17431
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41537
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14649
BRD-K39985369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03457
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.53651
forms	GeneRIF Biological Term Annotations	1.0	null
Carotid artery dissection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.755
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lipomatous tumor	HPO Gene-Disease Associations	1.0	null
superficial stratum of OCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02086
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30935
abnormality of lymphocytes	GWASdb SNP-Phenotype Associations	1.0	0.359537
shows	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8206-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arterial calcification of infancy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.672
AK2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_5_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
relatives	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3098
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.54718
methylationdependent	GeneRIF Biological Term Annotations	1.0	null
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
18691415-Table5d	GeneSigDB Published Gene Signatures	1.0	null
abnormal bleeding	HPO Gene-Disease Associations	1.0	null
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69817695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52448
NCI-H345	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.57904
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREBRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56441
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A8-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357802
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48419
primary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26947
multiple lipomas	HPO Gene-Disease Associations	1.0	null
abnormal heart morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K36363294_I-BET151_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
mTert_OE_GDS1211_256_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05173
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21758
ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE188382_4_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Red Blood Cell Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54822
BRD-K09602097_Forskolin_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19973
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.82915
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
generalized abnormality of skin	HPO Gene-Disease Associations	1.0	null
PMC8586238-41467_2021_26788_MOESM6_ESM.xlsx-S2A_CDE_genes-S2A_CDE_-_genes_of_the_two_CCD_genes_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
TERF2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01409
col10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
PEO-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872841
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91777
Prostate adenocarcinoma_PRAD_TCGA-Y6-A8TL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.121357
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung cancer	GWASdb SNP-Disease Associations	1.0	0.834806
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6-azathymine-2827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JHH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27449
Prostate adenocarcinoma_PRAD_TCGA-EJ-7317-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MalFGK2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
myocardial infarction	HPO Gene-Disease Associations	1.0	null
GTEX-R55C-0526-SM-3GIKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947521
Hypermelanotic Macule	DisGeNET Gene-Phenotype Associations	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71486304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09892
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.77331
norcyclobenzaprine-2469	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890169
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75673
mantle zone of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
THP1	CCLE Cell Line Gene Expression Profiles	1.0	1.43805
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902243
Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
fluvoxamine-2913	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
revealing	GeneRIF Biological Term Annotations	1.0	null
PMC5637726__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal kidney vasculature morphology	MGI Mouse Phenotype Associations 2023	1.0	null
lysergol-4966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
symptoms	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-1290	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Retinal Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K60866521_idelalisib_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Abnormality of the eye	ClinVar Gene-Phenotype Associations 2025	1.0	null
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913202
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
NCIH2171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85973
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
abnormality of the vasculature of the eye	HPO Gene-Disease Associations	1.0	null
BRD-K91596921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18521
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904715
PMC5309296-18_2016_2401_MOESM3_ESM.xlsx-NFE2L2-Unnamed_0_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28	ChEA Transcription Factor Targets	1.0	null
BRD-K29684372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42116
HNF4A-19761587-HUMAN INTESTINAL CELL LINE CACO-2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K01281780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11999
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907951
Cementum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.496606
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cisapride-5305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
malformation of the heart and great vessels	HPO Gene-Disease Associations	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08156
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892829
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.31786
tetroquinone-4078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
naftifine-3536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tiabendazole-2479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pseudoxanthoma elasticum	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06831
Peripheral artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
ramifenazone-6097	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.19116
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.64887
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
acne	HPO Gene-Disease Associations	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.987366
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402901
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19204
Motor Skills Disorders	CTD Gene-Disease Associations	1.0	1.01852
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
vision	GAD High Level Gene-Disease Associations	1.0	0.295739
gene expression	GO Biological Process Annotations 2025	1.0	null
EMC-BAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
particular	GeneRIF Biological Term Annotations	1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.911
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00501
PPARD	ChEA Transcription Factor Targets	1.0	null
Nephrocalcinosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39382
BRD-A50684349_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.012
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
nordihydroguaiaretic acid-1003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11886
Nausea	CTD Gene-Disease Associations	1.0	1.69513
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10236
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35059
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26432
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
ABC transporters	KEGG Pathways 2026	1.0	null
Angioid streaks	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.752
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.95195
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	1.49163
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.942794
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12443
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29502
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047267
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27122
diflunisal-4210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Etoposide	DrugBank Drug Targets	1.0	null
upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913339
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4783
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0882
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14075
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80699
Daoy	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.49693
BRD-K60547079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92214
hsa-miR-3187-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Skin Diseases	CTD Gene-Disease Associations	1.0	1.59148
Ca-Ski	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.71991
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
abnormal skin morphology	MPO Gene-Phenotype Associations	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48004
CRCGN014_HEPG2_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17485
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55666
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
LYPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02715
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CADASIL 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.88
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50368
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850858
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.06442
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862403
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27702
Inflammation	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
SEMA4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23244
PMC12119775-13402_2024_1033_MOESM1_ESM.pdf-15-ENSG00000067082_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3311-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66071
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GN-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blue sclerae	HPO Gene-Disease Associations	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.59191
BRD-K97721960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07175
layer 5 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16198
ES4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.38535
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.575
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05867
TST	MSigDB Cancer Gene Co-expression Modules	1.0	null
Skin Abnormalities	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7291824__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35281
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pneumonia	CTD Gene-Disease Associations	1.0	1.16733
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.125539
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Cholestasis	CTD Gene-Disease Associations	1.0	1.77743
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bone Marrow Diseases	CTD Gene-Disease Associations	1.0	1.16799
HLX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00470662
BRD-A79768653_sirolimus_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56181
BRD-K29652917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26391
BRD-K36557327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67372
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83701
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.24874
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40776
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00978
dermal atrophy	HPO Gene-Disease Associations	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00568
Accelerated Atherosclerosis	DisGeNET Gene-Phenotype Associations	1.0	null
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19118
BRD-K64642496_-666_MCF7_24.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF12_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883676
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065108
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.794247
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.65565
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01862
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11505
Cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
Lung squamous cell carcinoma_LUSC_TCGA-56-7731-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glioma	DisGeNET Gene-Disease Associations	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
ATG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.443
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.286519
erk12hnf4alpha	GeneRIF Biological Term Annotations	1.0	null
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
DOTC2-4510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Groin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.47
abnormal lipoprotein level	MPO Gene-Phenotype Associations	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930938
GBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55051
neoplasm of fatty tissue	HPO Gene-Disease Associations	1.0	null
BRD-K19862308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08162
Kyphosis Deformity Of Spine	DisGeNET Gene-Phenotype Associations	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79022
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.285138
pruritus	HPO Gene-Disease Associations	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.124
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37565
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83752
ASCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34495
GTEX-XYKS-1226-SM-4BRVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879799
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
calcium ion homeostasis	GO Biological Process Annotations 2023	1.0	null
hsa-miR-3064-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
monensin-3443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
accounted	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4SW-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48273
tissuespecific	GeneRIF Biological Term Annotations	1.0	null
enough	GeneRIF Biological Term Annotations	1.0	null
BRD-K77908580_entinostat_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49959
Eye cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lateral orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844242
dystrophic cardiac calcinosis	MPO Gene-Phenotype Associations	1.0	null
Perturb_266_KO_ADIRFAS786_SRP366780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.81906
hsa-miR-636	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952798
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13039
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
BRD-K99749624_S1003_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50997
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.22835
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27825
mantle zone of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37016
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31973
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26663
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
BRD-K50127933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22311
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE157050,GSE157051_2_v_9_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958158
superficial stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07279
gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.898188
Sphingolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
mv.1.lu	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
Aortic valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.447
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12683
BRD-A62809825_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Stroke	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44857
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3183
BRD-K26954192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87629
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2041
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.628697
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65867
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN013_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31492
lead	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.57134
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13396
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.302584
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Magnesium Chloride	CTD Gene-Chemical Interactions	1.0	null
individuals	GeneRIF Biological Term Annotations	1.0	null
HOP92	CCLE Cell Line Gene CNV Profiles	-1.0	-2.42033
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormally lax or hyperextensible skin	HPO Gene-Disease Associations	1.0	null
arterial calcification	HPO Gene-Disease Associations	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K89742282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0512
Probenecid	CTD Gene-Chemical Interactions	1.0	null
YAP1	ChEA Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55487965_NCGC00182364-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OVCAR-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
19061838-TableS13	GeneSigDB Published Gene Signatures	1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20364
BRD-K66884694_NCGC00167398-02_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Vomiting	CTD Gene-Disease Associations	1.0	1.57829
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75791
Colonic Neoplasms	CTD Gene-Disease Associations	1.0	1.26978
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10956
VMRC-RCZ	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.24746
GSE157233_1_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26567
cholesterol	GeneRIF Biological Term Annotations	1.0	null
Retinopathy, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K91467861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07562
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21457
HPN	MSigDB Cancer Gene Co-expression Modules	1.0	null
nephrocalcinosis	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-N87 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
Finnish congenital nephrotic syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
Myocardial Infarction	CTD Gene-Disease Associations	1.0	1.22436
propranolol-5358	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26161
cefotaxime-5830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Myositis	CTD Gene-Disease Associations	1.0	1.21141
pseudoxanthoma elasticum, forme fruste	OMIM Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-DX-A7EM-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MIAPACA2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08552
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.7977
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Renovascular hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06515
mantle zone of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21351
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18877
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16779
PGLYRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25373
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01607
HSG	BioGPS Cell Line Gene Expression Profiles	1.0	0.982142
EFE184	CCLE Cell Line Gene CNV Profiles	1.0	1.33705
neoplasm of head and neck	GWASdb SNP-Phenotype Associations	1.0	0.729372
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_2_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
response to drug	GO Biological Process Annotations 2015	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054611
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00594
BRD-K75545951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06025
BRD-K07691486_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01654
all	GWASdb SNP-Phenotype Associations	1.0	0.047639
GSE145249_0_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
BRD-K13275816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55348
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pkd1	GeneRIF Biological Term Annotations	1.0	null
Patterned macular dystrophy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.85
Heart Diseases	CTD Gene-Disease Associations	1.0	2.09776
Papule	ClinVar Gene-Phenotype Associations 2025	1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.41325
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-siYAP_myc_bound-MYC_targets_from_chipseq_atlas_at_least_2_chip-seqs_over_4_in_A459_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57651
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.64147
BRD-K10404799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06207
exons	GeneRIF Biological Term Annotations	1.0	null
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.082728
BRD-K64890080_BI-2536_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
overlap	GeneRIF Biological Term Annotations	1.0	null
Autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K62964360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09248
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937049
Brain capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
HPX	MSigDB Cancer Gene Co-expression Modules	1.0	null
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.77027
TMEM86A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46207
evidence	GeneRIF Biological Term Annotations	1.0	null
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63877
abnormality of ion homeostasis	HPO Gene-Disease Associations	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
SW579	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16233
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bretylium tosilate-3057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07491
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
naltrindole-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49744
Abnormal Platelets	DisGeNET Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3948
L-methionine sulfoximine-4070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.04047
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7147
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32965188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44691
BRD-K09432998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02309
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.58
Cerebral Calcification	DisGeNET Gene-Phenotype Associations	1.0	null
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47229
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.10511
Nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21199
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54606
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.296631
Carbon Tetrachloride	CTD Gene-Chemical Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4314	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hsa-miR-4756-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54099
large intestine cancer	GWASdb SNP-Disease Associations	1.0	0.458465
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31596
purine ribonucleotide transport	GO Biological Process Annotations 2025	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.95222
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1437	CCLE Cell Line Gene Expression Profiles	1.0	1.89842
Hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
HCMEC/D3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24944
GTEX-W5X1-1426-SM-3GIKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24726
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7236
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73B-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76236
Perturb_17486_KO_Otub2_SRP314435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.16155
Generalized arterial calcification of infancy 2	ClinVar Gene-Phenotype Associations	1.0	null
p-p-bond-hydrolysis-driven transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28992
severity	GeneRIF Biological Term Annotations	1.0	null
SAGA-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.176
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03254
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62216
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2803-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26254
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.298214
GSE132386_1_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUBA1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96659
NR1I2	ChEA Transcription Factor Targets	1.0	null
cerebral hemorrhage	HPO Gene-Disease Associations	1.0	null
BRD-K71726959_N9-isoproplyolomoucine_A549_24.0_h_122.55_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
diloxanide-3062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anorexia	CTD Gene-Disease Associations	1.0	1.78033
hsa-miR-337-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RELA	ChEA Transcription Factor Targets	1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.218
Becker disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Intracranial aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.66452
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
decreased central vision	HPO Gene-Disease Associations	1.0	null
deletion	GeneRIF Biological Term Annotations	1.0	null
elastic fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.80588
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040536
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93085
BRD-K49981566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29113
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04489
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88225
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68026
Retinoblastoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hereditary arterial and articular multiple calcification syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.06
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.94867
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Dyspnea	CTD Gene-Disease Associations	1.0	1.26607
BRD-K55187425_ON-01910_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fetal ultrasound soft marker	HPO Gene-Disease Associations	1.0	null
Meningococcal infection_Umbilical vein_GSE4646	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.22453
BRD-K84685162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91557
testicular cancer	GWASdb SNP-Disease Associations	1.0	0.834806
Dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.979
Sublaterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42966
estradiol-1021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04869
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80604
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.18939
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.999314
hypophosphatemia	HPO Gene-Disease Associations	1.0	null
GOTO	GDSC Cell Line Gene Expression Profiles	-1.0	-2.09213
BRD-A56592690_PX12_MCF7_24.0_h_30.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31219
BRD-K41895714_AS-605240_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94489736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18116
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K23704908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43327
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.826
GSE196199_0_v_1_zbtb20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vinblastine	DrugBank Drug Targets	1.0	null
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.35774
caco2	HPA Cell Line Gene Expression Profiles	1.0	1.04239
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.257
MUTZ5	CCLE Cell Line Gene CNV Profiles	1.0	1.35517
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.139715
Visual areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76313
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
propylthiouracil-4076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal circulating creatinine level	MPO Gene-Phenotype Associations	1.0	null
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
Anemia, Aplastic	CTD Gene-Disease Associations	1.0	1.08091
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26195700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14121
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disseminated Intravascular Coagulation	CTD Gene-Disease Associations	1.0	1.42994
MAZ	ENCODE Transcription Factor Targets	1.0	null
renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.555274
BRD-A71765365_Reserpine_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Diarrhea	CTD Gene-Disease Associations	1.0	1.22758
BRD-K52231520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88569
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
SOX10	JASPAR Predicted Transcription Factor Targets	1.0	null
Autosomal recessive congenital ichthyosis 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.936
fiber	GeneRIF Biological Term Annotations	1.0	null
isoxsuprine-4205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
transcription	GeneRIF Biological Term Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58582
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.01907
abnormality of male external genitalia	GWASdb SNP-Phenotype Associations	1.0	0.248404
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881572
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.927876
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03815
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05783
IMR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Superficial temporal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.9452
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.370479
Cobalamin transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11717
BRD-K40685792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16694
NR4A1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Abnormality Of The Sternum	DisGeNET Gene-Phenotype Associations	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161139
premature occlusive vascular disease	HPO Gene-Disease Associations	1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-6215-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.127162
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.98376
HEPG2	CCLE Cell Line Gene CNV Profiles	1.0	1.53066
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975548
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93255
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27529556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71088
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40323
fluoxetine-5356	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	2.0562
guide	GeneRIF Biological Term Annotations	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09718
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.990154
abnormality of the thorax	HPO Gene-Disease Associations	1.0	null
bilirubin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.550134
caki2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47092
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.954749
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852447
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal vasculopathy with cerebral leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
prochlorperazine-6664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
efflux	GeneRIF Biological Term Annotations	1.0	null
Cardiovascular system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K45665532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26865
Hepatitis	DisGeNET Gene-Disease Associations	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
abnormality of prenatal development or birth	HPO Gene-Disease Associations	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
Fibrodysplasia ossificans progressiva	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.08868
decreased susceptibility to dystrophic cardiac calcinosis	MPO Gene-Phenotype Associations	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.18635
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
eye cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CYP2B6	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02209
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K27953820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18824
GTEX-S4P3-1226-SM-4AD4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.139
Perturb_1080_OE_ZBED2_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K30171122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29748
BRD-K39979888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64683
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.719
BRD-K17743125_belinostat_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of the sclera	HPO Gene-Disease Associations	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48254
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30913
PMC6119347__F2	PFOCR Pathway Figure Associations 2024	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09033
south	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38188
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847308
Artery disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25395
Hematuria	CTD Gene-Disease Associations	1.0	1.72529
RAB3A_KO_GDS2482_705_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41249
BRD-K70511574_sunitinib_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11458
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09773
angioid streaks	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.58279
BRD-K52859120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74149
BRD-K21579116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06135
BRD-K00231307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54492
hsa-miR-890	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Severe Visual Impairment	DisGeNET Gene-Disease Associations	1.0	null
Blue Sclera	DisGeNET Gene-Phenotype Associations	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.93352
adenosine	GeneRIF Biological Term Annotations	1.0	null
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
Perturb_7747_KD_CNOT1_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.61801
BRD-K72050226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21691
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842981
BRD-K72713703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24216
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92637
abnormality of blood and blood-forming tissues	HPO Gene-Disease Associations	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	2.37207
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41402
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.384665
conditions	GeneRIF Biological Term Annotations	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
Basal ganglia calcification	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
aortic	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.233459
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21171
pipenzolate bromide-4484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28277
SW403	CCLE Cell Line Gene Expression Profiles	1.0	1.81626
Ebolavirus(ZEBOV)_6hr_Macrophage_22028943_GSE31747	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.35442
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864372
adenine nucleotide transport	GO Biological Process Annotations 2023	1.0	null
norcyclobenzaprine-4190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_16003_KO_7p15.2_SRP107176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.54958
Mitral valve prolapse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.06297
cerebrovascular	GeneRIF Biological Term Annotations	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37186
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08966
BRD-K16843478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0366
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
liver	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56248
Primary somatosensory area, mouth, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53615
abnormality of cardiac morphology	HPO Gene-Disease Associations	1.0	null
abnormality of the palate	HPO Gene-Disease Associations	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9708
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.983233
Medial Calcification Of Medium-Sized Arteries	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30859
BRD-K21680192_mitoxantrone_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58492
serves	GeneRIF Biological Term Annotations	1.0	null
CaR-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.83829
ZBTB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88101
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	1.0	2.89523
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.35301
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3172
Photodynamic therapy induced NFE2L2 NRF2 survival signaling	WikiPathways Pathways 2024	1.0	null
Osteogenesis imperfecta	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
BRD-K77869064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22313
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.789
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2023	1.0	null
BRD-K02708799_GSK-1059615_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A46747628_Ouabain_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04791
abnormal skin adnexa morphology	MPO Gene-Phenotype Associations	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K16047442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87088
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1349
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902293
Aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8644
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ML-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nglycosylation	GeneRIF Biological Term Annotations	1.0	null
BRD-K09951645_dabrafenib_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.14485
hsa-miR-625	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830322
dutch	GeneRIF Biological Term Annotations	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ovary adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23176
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	106.655
HS616T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89904
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immune system disease	GWASdb SNP-Disease Associations	1.0	0.064212
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.95072
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
BRD-K87909389_alvocidib_SKBR3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50385
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Early Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
hemoglobin a, glycosylated	GAD Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Cerebral arterial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50401
CHD2	ENCODE Transcription Factor Targets	1.0	null
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.956356
Poisoning	CTD Gene-Disease Associations	1.0	1.40568
BRD-K46400317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31628
PMC3888473__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.836109
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cycloserine-6139	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Peroxisomal biogenesis disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7334
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40555
Coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.755
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.5887
hsa-miR-219-1-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Anemia, Hemolytic	CTD Gene-Disease Associations	1.0	1.65249
possible	GeneRIF Biological Term Annotations	1.0	null
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.362422
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42181
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21686
BRD-K84052780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22137
hsa-miR-4681	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57875
Perturb_3698_KD_FTO_SRP226373	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.44844
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urea cycle disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08819
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06409
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14654
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1782
GTEX-TMZS-0226-SM-3DB9N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01368
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-A71765365_Reserpine_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Substance Withdrawal Syndrome	CTD Gene-Disease Associations	1.0	1.13793
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the dura mater	HPO Gene-Disease Associations	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81922
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01069
BRD-K77908580_entinostat_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63899
ABC-type glutathione S-conjugate transporter activity	GO Molecular Function Annotations 2023	1.0	null
Perturb_11187_KO_Trp53/Gdown1_SRP244620	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.11148
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
PDSS2_KO_GDS3454_120_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0969
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04016
BRD-K99277076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50945
cterminal	GeneRIF Biological Term Annotations	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74793
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.028687
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.14509
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Primary localized cutaneous amyloidosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982689
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68496
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K49865102_PD-0325901_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K91836330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43987
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68803
Ventricular Dysfunction, Left	CTD Gene-Disease Associations	1.0	1.23743
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43717
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52194153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51485
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_ATF5-Logfold_change_threshold_1_0_1_ATF5	Rummagene Transcription Factor Associations 2026	1.0	null
Hypotension	CTD Gene-Disease Associations	1.0	1.40429
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H6-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39476
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64533
Neurofibroma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.735764
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormalities of the peripheral arteries	HPO Gene-Disease Associations	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3137	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K74881104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97931
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80613
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary Biliary Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
abnormal kidney morphology	MPO Gene-Phenotype Associations	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A63590986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43535
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4546
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
N-acetylmuramic acid-4582	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Diseases	CTD Gene-Disease Associations	1.0	1.88277
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
GTEX-X261-0226-SM-3NMD2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30467
GSE62843,GSE64371_2_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OSC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.122954
Learning Disorders	CTD Gene-Disease Associations	1.0	1.80586
Renal Insufficiency	CTD Gene-Disease Associations	1.0	1.76907
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.49354
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4679	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Exanthema	DisGeNET Gene-Phenotype Associations	1.0	null
ioversol-3026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8172-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exfoliation Syndrome	DisGeNET Gene-Disease Associations	1.0	null
ATXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05882
PPARA_KO_GDS3748_516_mouse_Livers	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
psi2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.492
External encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.49
sirolimus-1045	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930938
GSTM1	MSigDB Cancer Gene Co-expression Modules	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20093
Streptozocin	CTD Gene-Chemical Interactions	1.0	null
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.587629
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.887
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969223
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.24486
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41991
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9492
BRD-K06251362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20134
organic anion transport	GO Biological Process Annotations 2025	1.0	null
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864352
BRD-K81418486_vorinostat_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.187719
mdck-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04577
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Arterial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.976
YKG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53523
BRD-K13390322_AT-7519_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02099
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78195641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.83633
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08156
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
abnormality of the vertebral column	HPO Gene-Disease Associations	1.0	null
BRD-K42976515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23997
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45746021_CC-401_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K27035180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70404
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23855
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.3138
subset	GeneRIF Biological Term Annotations	1.0	null
BRD-K72933250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33523
Perturb_8347_KD_YY1_SRP286033	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.7106
genotype	GeneRIF Biological Term Annotations	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21237
did	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
racecadotril-1782	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
site	GeneRIF Biological Term Annotations	1.0	null
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.860971
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856369
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K97842654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58562
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
High, Narrow Palate	DisGeNET Gene-Phenotype Associations	1.0	null
lesional	GeneRIF Biological Term Annotations	1.0	null
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00847
Weight Gain	CTD Gene-Disease Associations	1.0	1.56755
changes	GeneRIF Biological Term Annotations	1.0	null
localized skin lesion	HPO Gene-Disease Associations	1.0	null
Chest Pain	CTD Gene-Disease Associations	1.0	1.06261
Acidosis	CTD Gene-Disease Associations	1.0	1.29471
Renal Colic	DisGeNET Gene-Phenotype Associations	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.162468
restrictive cardiomyopathy	HPO Gene-Disease Associations	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09868
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
diseasecausing	GeneRIF Biological Term Annotations	1.0	null
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
teleangiectasia of the skin	HPO Gene-Disease Associations	1.0	null
Cerebellar Diseases	CTD Gene-Disease Associations	1.0	1.29781
SK-N-FI	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58464
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.106098
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.91
Acute Gastroenteritis	DisGeNET Gene-Disease Associations	1.0	null
kyphosis	HPO Gene-Disease Associations	1.0	null
MET_knockout_253_GSE30651	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.44084
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00826
E2F2_KD_GDS4094_447_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K02708799_GSK-1059615_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
wortmannin-2703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56398
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Musculoskeletal system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
infancy	GeneRIF Biological Term Annotations	1.0	null
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08697
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.733
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01201
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2438
modulated	GeneRIF Biological Term Annotations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00382
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857807
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056557
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebrovascular Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
PANC-04-03	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.10225
BRD-K61551681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.59543
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.425344
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12205
SNU283	CCLE Cell Line Gene Expression Profiles	1.0	1.4383
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26822
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12232
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11715
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
naltriben-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0327
BRD-K23975481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05416
Hypertriglyceridemia	CTD Gene-Disease Associations	1.0	1.09822
myopia	HPO Gene-Disease Associations	1.0	null
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18461
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67113
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59817
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16921
tretinoin-991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89075
Glioma stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841524
ERBB2_knockdown_238_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.03399
EP300	ChEA Transcription Factor Targets	1.0	null
BRD-K21332842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79908
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12238
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.39132
abnormality of the male genitalia	GWASdb SNP-Phenotype Associations	1.0	0.226748
BRD-K84586608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08793
15297395-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
basolateral	GeneRIF Biological Term Annotations	1.0	null
BRD-K21193980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33288
AIRE_KO_GDS2015_33_mouse_thymic epithelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07121
NALM6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
moyamoya disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.17952
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sulfinpyrazone	HMDB Metabolites of Enzymes	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20276
BRD-K60296400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57738
Precancerous Conditions	CTD Gene-Disease Associations	1.0	2.0094
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.870639
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K08311368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06952
accompanied	GeneRIF Biological Term Annotations	1.0	null
calcification	GeneRIF Biological Term Annotations	1.0	null
cytosolic	GeneRIF Biological Term Annotations	1.0	null
BRD-K29338816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24655
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50008138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70381
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GT-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Leukemia, Myeloid, Acute	CTD Gene-Disease Associations	1.0	1.03009
BRD-K95521279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1822
NR2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.39907
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Angioid Streaks	DisGeNET Gene-Disease Associations	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.912426
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13039
NB1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K00317371_-666_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K64425085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11207
Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
OE19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.70068
congestive heart failure	HPO Gene-Disease Associations	1.0	null
BRD-K48922193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53627
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
PMC4686057-pone.0145107.s001.xlsx-CAA-C-Unnamed_0_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.70906
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7105
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8548
BRD-K23749313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30993
BRD-K66179451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91581
BRD-K37033753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59388
BRD-K30176130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25812
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993108
BRD-K18190982_COT-10b_A549_24.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K59491482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20439
ectopic	GeneRIF Biological Term Annotations	1.0	null
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873037
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40465
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64407
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
BRD-K29420358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06268
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84145
mantle zone of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01711
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
level	GeneRIF Biological Term Annotations	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06515
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO Molecular Function Annotations 2015	1.0	null
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.25458
pyrophosphatase activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-599	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A520-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86002795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91261
enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320956
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5639-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A62184259_Cycloheximide_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-DX-A1L2-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48743
Combined deficiency of vitamin K-dependent clotting factors 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
GSE146074_0_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Striatum ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0045
peripheral arterial disease	HPO Gene-Disease Associations	1.0	null
ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cerebral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05655
lipoprotein	GeneRIF Biological Term Annotations	1.0	null
Cardiac Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
Restrictive cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hemoglobin levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.30458
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38113
GTEX-WFG7-1726-SM-4LVME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867311
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057941
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
Cerebral Infarction	CTD Gene-Disease Associations	1.0	1.02708
BRD-K99529078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04116
Sickle cell disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054891
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.34765
LIVF001-025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74706
nicergoline-1374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.30083
tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.122867
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.098
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35569
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836025
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	0.682796
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47146
Perturb_10168_KO_TOP2A_SRP297586	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.93097
BRD-K60623809_SU11652_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.0977
BRD-K20470077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11026
promoter	GeneRIF Biological Term Annotations	1.0	null
PMC7217064-IJC-146-3354-s005.xlsx-Table_S6-Supplementary_Table_S6_Genes_significantly_upregulated_in_OC2-transfected_MKN74_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35716340_-666_AGS_6.0_h_12.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.39
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11426
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0417
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.365
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.17201
BRD-K08881846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60787
calcinosis	MGI Mouse Phenotype Associations 2023	1.0	null
Gastrointestinal Hemorrhage	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34336
BRD-K50623282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03298
Atherosclerosis	DisGeNET Gene-Disease Associations	1.0	null
parahippocampal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.492572
Renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
abilities	GeneRIF Biological Term Annotations	1.0	null
Retinitis pigmentosa 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36874
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Pseudoxanthoma elasticum	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE216326_2_v_1_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885159
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RH-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.1155
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2041
Disease Exacerbation	DisGeNET Gene-Phenotype Associations	1.0	null
delsoline-5858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
probably	GeneRIF Biological Term Annotations	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
BRD-K74305673_IMD 0354_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.212608
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.334
Coronary Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Otopalatodigital syndrome spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24392
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.357
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12806
BRD-K14875480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05718
BRD-K61560971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49113
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44008
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	2.11116
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14271
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995985
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906094
Arterial Calcification	DisGeNET Gene-Phenotype Associations	1.0	null
abnormality of thrombocytes	HPO Gene-Disease Associations	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07395346_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51295743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14726
Impaired Glucose Tolerance	DisGeNET Gene-Phenotype Associations	1.0	null
plagl1	GeneRIF Biological Term Annotations	1.0	null
BRD-K76616863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77718
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
hMPV_6Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.33189
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96478
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene CNV Profiles	1.0	1.49163
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K08679933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0441
BRD-K03449891_foretinib_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hyperalgesia	CTD Gene-Disease Associations	1.0	1.62512
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86574132_-666_MCF7_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24879
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95685_2_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01561
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.73
benserazide-6722	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850643
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8928
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.927886
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.936214
GSE133213_9_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
monensin-2580	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13039
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69724
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828759
abnormality of the head	HPO Gene-Disease Associations	1.0	null
ABC transporter disorders	Reactome Pathways 2024	1.0	null
Ossification of the posterior longitudinal ligament of spine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Necrosis	CTD Gene-Disease Associations	1.0	2.4797
Lung adenocarcinoma_LUAD_TCGA-95-8039-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3395
GATA1	ENCODE Transcription Factor Targets	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.75
NCI-H2291	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
diagnosed	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Cerebral infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
arterial endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190389
Liver Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
partial	GeneRIF Biological Term Annotations	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03645
BRD-K18863894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0963
ABC-family proteins mediated transport	Reactome Pathways 2014	1.0	null
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57875
GTEX-XQ8I-2126-SM-4BOOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897614
DGAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00592714
Peau D'Orange Retinal Changes	DisGeNET Gene-Phenotype Associations	1.0	null
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81389
15297395-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K02614439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0999
trimethylcolchicinic acid-2146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SAFB2_02_150	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64386
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906591
cardiac	GeneRIF Biological Term Annotations	1.0	null
abnormality of joint mobility	HPO Gene-Disease Associations	1.0	null
hydrolase activity, acting on acid anhydrides	GO Molecular Function Annotations 2015	1.0	null
abnormality of the curvature of the vertebral column	HPO Gene-Disease Associations	1.0	null
neoplasm by anatomical site	HPO Gene-Disease Associations	1.0	null
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92807
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.024
implicated	GeneRIF Biological Term Annotations	1.0	null
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31876
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PK-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCV JFH-1_24Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.43491
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.58842
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874793
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08778
arterial calcification of infancy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.07077
PMC9692021-Table_4.xlsx-Table_S4-Table_S4_405_DEGs_of_RA_synovial_tissues_between_NFIL3-high_and_NFIL3-low_group_NFIL3	Rummagene Transcription Factor Associations 2026	1.0	null
internal hemorrhage	HPO Gene-Disease Associations	1.0	null
inducing	GeneRIF Biological Term Annotations	1.0	null
Enthesopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
A549_PHA-680632_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117101
NCI-H1437 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47372
abnormality of the endocrine system	HPO Gene-Disease Associations	1.0	null
heart valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.581996
BRD-K76942055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44917
Blepharochalasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
CCK-81	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.00385
BRD-K92571446_WZ-3105_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17955
Hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.45229
domaindomain	GeneRIF Biological Term Annotations	1.0	null
generalized	GeneRIF Biological Term Annotations	1.0	null
BRD-K84988480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13913
CCDC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04159
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11865
BRD-K26765362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03633
Nephrolithiasis	DisGeNET Gene-Disease Associations	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00939
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98554
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.059
ZNF705B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89438
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70265
abnormality of the systemic arterial tree	HPO Gene-Disease Associations	1.0	null
tail	GeneRIF Biological Term Annotations	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63611
Sulfinpyrazone	DrugBank Drug Targets	1.0	null
SP1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42975
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04687
PMC9601604-NIHMS1841143-supplement-SuppTable-3.xlsx-shared_downregulated-Genes_downregulated_in_the_absence_of_FOXO3_in_GSCs_and_aged_NSCs_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20621
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7101
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K85200795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08152
does	GeneRIF Biological Term Annotations	1.0	null
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.87375
GTEX-WY7C-2426-SM-3NB2V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917669
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976382
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2579
heterozygote	GeneRIF Biological Term Annotations	1.0	null
spectroscopy	GeneRIF Biological Term Annotations	1.0	null
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20602
647-V	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.95462
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52731
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28199
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17766
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
glioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
encodes	GeneRIF Biological Term Annotations	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17705
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25371
labelling	GeneRIF Biological Term Annotations	1.0	null
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867649
hematological	GAD High Level Gene-Disease Associations	1.0	0.295739
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02388
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.5047
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
postcentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917828
Acute Myeloid Leukemia_LAML_TCGA-AB-2911-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MCF7_KD-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE204784,GSE204787_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal cholesterol homeostasis	MPO Gene-Phenotype Associations	1.0	null
BRD-K88573743_A443654_SKBR3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.667
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29174
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.01036
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23978
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
OVCA433	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10519
extrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.347511
BRD-K07278815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67968
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05476
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2515
SREBF1	ChEA Transcription Factor Targets	1.0	null
Abnormality Of The Thorax	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08784
BL2464 (TGS1)	NURSA Protein Complexes	1.0	null
alter	GeneRIF Biological Term Annotations	1.0	null
decreased circulating HDL cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
Ischemic Stroke	DisGeNET Gene-Disease Associations	1.0	null
UACC-257 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.996228
midecamycin-5345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K77273085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06848
BRD-K54785691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25971
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.537021
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K92428232_GSK-461364_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-5156-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
atpase activity	GO Molecular Function Annotations 2015	1.0	null
LCLC-97TM1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
superior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09477
nt5e	GeneRIF Biological Term Annotations	1.0	null
arterial calcification, generalized, of infancy, 2	OMIM Gene-Disease Associations	1.0	null
iobenguane-7299	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	0.890415
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927341
mitral valve prolapse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.587444
Renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.721
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7527
Multiple Lipomata	DisGeNET Gene-Disease Associations	1.0	null
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05241
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75023
Acute Myeloid Leukemia_LAML_TCGA-AB-2948-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	6.96742
BRD-A80960055_3203_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886459
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
Neutropenia	CTD Gene-Disease Associations	1.0	1.49711
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.486
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.636
sulfathiazole-4183	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81298
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1654
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
BRD-K83715372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26945
Phosphates	CTD Gene-Chemical Interactions	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
pseudoxanthoma elasticum	OMIM Gene-Disease Associations	1.0	null
RAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64315
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43694
mediating	GeneRIF Biological Term Annotations	1.0	null
BRD-K45589340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45483
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Superior mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
Skin Diseases, Viral	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K26140483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3075
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.094559
lattice corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.362609
Perturb_11054_KO_Mettl3_SRP363782	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.65809
LEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33872
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19817
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.39963
Cholestasis, Intrahepatic	CTD Gene-Disease Associations	1.0	1.48582
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2388
Sitosterolemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21259
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.09939
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gastrointestinal Diseases	CTD Gene-Disease Associations	1.0	1.74119
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Clitoral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.571
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08212599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19523
Inner chondrogenic layer of perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
LY-294002-1157	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
etifenin-2477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
transcriptional	GeneRIF Biological Term Annotations	1.0	null
piromidic acid-2996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Femoral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
BRD-K40112492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52802
increased circulating creatinine level	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827481
multiple	GeneRIF Biological Term Annotations	1.0	null
abnormality of the meninges	HPO Gene-Disease Associations	1.0	null
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26315
chemical	GeneRIF Biological Term Annotations	1.0	null
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32902
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18126
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	2.15917
Atrophy	CTD Gene-Disease Associations	1.0	1.47322
BRD-K99252563_QL-XII-47_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
liver	GTEx Tissue Gene Expression Profiles	1.0	2.08555
sensory perception	GO Biological Process Annotations 2015	1.0	null
sulfabenzamide-2159	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Progressive familial intrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
Retinal cone dystrophy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
cerebral arterial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.121563
External carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
hesperetin-5350	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10022
BHY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64015
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32966
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.924
rifampicin-2487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tolbutamide-4540	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03785
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.75728
RUNX2_NULL MUTATION_GDS2184_719_mouse_Embryonal bone (MG-U74A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11483
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08033
Joint Hyperflexibility	DisGeNET Gene-Phenotype Associations	1.0	null
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LCAT	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K16189898_CHIR-99021_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Episodic kinesigenic dyskinesia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
relevant	GeneRIF Biological Term Annotations	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87774
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04028
BRD-K90358614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13631
variations	GeneRIF Biological Term Annotations	1.0	null
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
A549_Alvespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118278
Eosinophilia	CTD Gene-Disease Associations	1.0	1.38724
Basal plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.231
16728581-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K72467884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34275
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
Spastic Paraplegia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K37510443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04423
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05259
abnormality of the falx cerebri	HPO Gene-Disease Associations	1.0	null
phosphate ion homeostasis	GO Biological Process Annotations 2023	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74074
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13968
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.19966
abnormality of higher mental function	GWASdb SNP-Phenotype Associations	1.0	0.256762
abnormal cholesterol level	MPO Gene-Phenotype Associations	1.0	null
Optic atrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
Coronary Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of skin pigmentation	HPO Gene-Disease Associations	1.0	null
BRD-K25540102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33614
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21169
GM2345	BioGPS Cell Line Gene Expression Profiles	1.0	0.838015
ethnic	GeneRIF Biological Term Annotations	1.0	null
monoatomic cation homeostasis	GO Biological Process Annotations 2025	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11942
BRD-K96615474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64282
families	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37565
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05857
BRD-K46419649_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
very	GeneRIF Biological Term Annotations	1.0	null
EE-66-CK83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238076
BRD-K07576726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04297
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09102
Ataxia	CTD Gene-Disease Associations	1.0	1.25183
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10504
GTEX-XGQ4-0826-SM-4AT4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992043
BRD-K54997624_BYL719_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RIF1_KD_GDS4943_13_mouse_J1 ESC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.486
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.668836
SLR20	CCLE Cell Line Gene CNV Profiles	1.0	1.6909
respectively	GeneRIF Biological Term Annotations	1.0	null
HCC2157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47309
monensin-1105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal uvea morphology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
neurological system process	GO Biological Process Annotations 2015	1.0	null
Primary somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
GSE70935_2_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
arterial stenosis	HPO Gene-Disease Associations	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28199
abnormal calcium ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.878
cardiomyopathy	HPO Gene-Disease Associations	1.0	null
BRD-K53417444_OTSSP167_HCC515_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
human brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234016
unlikely	GeneRIF Biological Term Annotations	1.0	null
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31956
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00734
abnormal lipid level	MPO Gene-Phenotype Associations	1.0	null
calcium folinate-2579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32723
Intracranial arterial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
reported	GeneRIF Biological Term Annotations	1.0	null
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881666
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5553784__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CLPP_KO_GDS4791_108_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.57435
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lingual gyrus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892462
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847816
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
SLX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39191
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51791049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08216
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48536
nucleus subcoeruleus, r1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56691
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834242
abnormality of the heart valves	HPO Gene-Disease Associations	1.0	null
BRD-K61388138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28425
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.127215
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	1.79859
BRD-K64075179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02297
BRD-K88679751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72957
Aortic smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
report	GeneRIF Biological Term Annotations	1.0	null
macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.333218
Moyamoya disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
thioridazine-1068	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
deficiency	GeneRIF Biological Term Annotations	1.0	null
CP-690334-01-3826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56245
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16137
Intrahepatic cholestasis of pregnancy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.252774
FOSL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.837666
visual impairment	HPO Gene-Disease Associations	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82076
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
BRD-K40061713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06786
BRD-K24950073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33534
BRD-K82768815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30998
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
layer 3 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58108
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49105
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SBC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86828
Thrombosis	CTD Gene-Disease Associations	1.0	1.23775
BRD-K56022813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23015
GSE182888_0_v_1_jmjd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
elastic	GeneRIF Biological Term Annotations	1.0	null
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977899
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056389
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.430695
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861026
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hypersensitive	GeneRIF Biological Term Annotations	1.0	null
Buschke-Ollendorff syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32824
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3Q8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98016463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19432
PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
Lung Diseases	CTD Gene-Disease Associations	1.0	1.66684
Gout	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
BRD-K34169251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79796
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2391
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7926-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229568
BRD-K76461283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3104
methylergometrine-6704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Perturb_2015_KO_Slamf9_SRP199215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.9265
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86832
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21603
Longissimus lumborum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
BRD-K04853698_LDN-193189_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FLCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52863
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A60245366_AS-601245_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857555
directly	GeneRIF Biological Term Annotations	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.29342
bruising susceptibility	HPO Gene-Disease Associations	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.122954
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.96968
PMC3888473__F3	PFOCR Pathway Figure Associations 2023	1.0	null
wm115	HPA Cell Line Gene Expression Profiles	-1.0	-2.39936
angioid streaks	GAD Gene-Disease Associations	1.0	null
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10886
CLPP_KO_GSE40207_397_mouse_Brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC5732738-oncotarget-08-103415-s002.xlsx-MFC-7_DEGs-Genes_with_significantly_different_expression_between_parental_MCF-7_and_GATA3_WT_clones_with_adjusted_P_value_0_05_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4514
DAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03833
abnormality of phosphate homeostasis	HPO Gene-Disease Associations	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27251
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38594
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994717
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37492
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865722
plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.109817
higher	GeneRIF Biological Term Annotations	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959556
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.765
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00939
PMC12354852-41467_2025_62818_MOESM3_ESM.xlsx-Sup_Data_10-Differentially_expressed_genes_in_TAF6L_KD_vs_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RBL1_KO_GDS1931_740_mouse_Neurospheres (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K71243741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76403
different	GeneRIF Biological Term Annotations	1.0	null
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837245
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859883
basolateral plasma membrane	GO Cellular Component Annotations 2023	1.0	null
Retinal Hemorrhage	DisGeNET Gene-Phenotype Associations	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-576-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17632
Long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.234
BRD-K83544408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54382
Microcephalic osteodysplastic primordial dwarfism type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12617
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12796
using	GeneRIF Biological Term Annotations	1.0	null
Penis_Foreskin_Keratinocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.35112
Moyamoya Disease	DisGeNET Gene-Disease Associations	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7806
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.855013
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acetylsalicylic acid-2664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IgG glycosylation	GWAS Catalog SNP-Phenotype Associations	1.0	0.057619
Perturb_17183_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15596
MID1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06615
Type 2 diabetes mellitus_Pancreas_GSE2470	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.54005
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40704
TAL1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45424
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.41586
Magnesium	CTD Gene-Chemical Interactions	1.0	null
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00274
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Cystitis	CTD Gene-Disease Associations	1.0	1.23616
CALU-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Iliac artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.179
hsa-miR-369-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
source	GeneRIF Biological Term Annotations	1.0	null
Organelle membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.316
Hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
Liver Failure	CTD Gene-Disease Associations	1.0	1.13245
Sickle cell anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.682
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26315
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95709431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03385
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
morphology	GeneRIF Biological Term Annotations	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37736
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14618467_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Demyelinating Diseases	CTD Gene-Disease Associations	1.0	1.22242
hsa-miR-603	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49393
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15831
hypophosphatemic rickets	HPO Gene-Disease Associations	1.0	null
BRD-K05374764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37082
pararosaniline-893	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4165
brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077715
BRD-K76755163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04686
haloperidol-1024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YMB1	CCLE Cell Line Gene Expression Profiles	1.0	1.54222
RBP2_deficiency_GDS2731_62_mouse_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K54351101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13542
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.27286
Myopia	DisGeNET Gene-Disease Associations	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12855
cardiac arrest	HPO Gene-Disease Associations	1.0	null
Intrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.786
Perturb_10695_KO_Rag2_SRP092590	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
factors	GeneRIF Biological Term Annotations	1.0	null
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
A-2780 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.028
BRD-K63996931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34707
slc20a2	GeneRIF Biological Term Annotations	1.0	null
BRD-K14449601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14649
BRD-K60759770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62182
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	Reactome Pathways 2024	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09872
URM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3015
ONS-76	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44096
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	2.80699
cognitive impairment	GWASdb SNP-Phenotype Associations	1.0	0.572823
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Get-1_Deficiency_GDS2629_161_mouse_embryonic skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
enilconazole-5113	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967448
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05142
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
persistent	GeneRIF Biological Term Annotations	1.0	null
BEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69039
anterior pretectal nucleus, dorsal superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07279
sf-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.838252
Hemoglobinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858731
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
CC-03-PW00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204848
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16083
sudden cardiac death	HPO Gene-Disease Associations	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.722
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21282
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16484
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
Vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.503
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5006-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metabolites	GeneRIF Biological Term Annotations	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.760237
BRD-K68174511_-666_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Vasospasm, Intracranial	CTD Gene-Disease Associations	1.0	1.1485
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889649
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2041
LS-411N	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.32274
Perturb_9125_OE_KDM2B_SRP359233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.67705
Notochord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
Basal laminar drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04999
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
abnormality of skin physiology	HPO Gene-Disease Associations	1.0	null
stroke	HPO Gene-Disease Associations	1.0	null
elasticumlike	GeneRIF Biological Term Annotations	1.0	null
dubin-johnson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.29615
abnormality of b cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.40409
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72059
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.493354
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36206
compound	GeneRIF Biological Term Annotations	1.0	null
Perturb_17186_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K98451611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27666
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930505
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.991109
Spine apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
NCI-H69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
first	GeneRIF Biological Term Annotations	1.0	null
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34328
calcified skin	MGI Mouse Phenotype Associations 2023	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54293
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.48751
Doxorubicin	HMDB Metabolites of Enzymes	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80535598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81834
Skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
hsa-miR-592	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Hepatoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
BRD-K49865102_PD-0325901_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
family	GeneRIF Biological Term Annotations	1.0	null
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997416
BRD-K49467822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90155
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14304
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79262
Nmyc_OE_GDS2406_14_mouse_LUNG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19318
parenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.284253
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13384
cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.353027
KMRC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A41692738_TGX-221_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of the sternum	HPO Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3938	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_12_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11499
alpha-estradiol-1048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.945706
Verapamil	CTD Gene-Chemical Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29858
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4676
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08774
GTEX-O5YT-1726-SM-3NMD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895127
cytokines	GeneRIF Biological Term Annotations	1.0	null
been	GeneRIF Biological Term Annotations	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.923767
Ehlers-Danlos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.974
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46005
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878014
abnormal kidney blood vessel morphology	MPO Gene-Phenotype Associations	1.0	null
PMC10685830-aim-26-346-s001.pdf-9-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Polyuria	CTD Gene-Disease Associations	1.0	1.07411
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846949
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93674
spiramycin-3419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C3A	GDSC Cell Line Gene Expression Profiles	1.0	2.78385
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
Osteomalacia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
rosiglitazone-1071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.446862
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
igrov-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.418099
lines	GeneRIF Biological Term Annotations	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01285
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03171
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA1_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.98517
BRD-A19500257_geldanamycin_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.533
BRD-K71253424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98422
tissues	GeneRIF Biological Term Annotations	1.0	null
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
BRD-K61189585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21683
MDA-MB-361	GDSC Cell Line Gene Expression Profiles	1.0	1.54026
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
describes	GeneRIF Biological Term Annotations	1.0	null
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24937
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06887
plasma membrane region	LOCATE Curated Protein Localization Annotations	1.0	null
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5243
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21939
Optic disk drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.005
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05754
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05633
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8128
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2425
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
Leukotriene C4	CTD Gene-Chemical Interactions	1.0	null
vascular skin abnormality	HPO Gene-Disease Associations	1.0	null
BRD-A91931411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69508
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.7778
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864597
phenotypic	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
bortezomib	CTD Gene-Chemical Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7820-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5605_KD|OE_METTL1|RPTOR_SRP312040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K12107215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13991
JUND	ENCODE Transcription Factor Targets	1.0	null
Perturb_690_KO_RORA_ERP111466	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.856053
Connective tissue disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61026
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37345
Coronary Heart Disease	DisGeNET Gene-Disease Associations	1.0	null
Jaundice	CTD Gene-Disease Associations	1.0	1.63339
Vasculitis, Leukocytoclastic, Cutaneous	CTD Gene-Disease Associations	1.0	1.2208
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057348
A2780	GDSC Cell Line Gene Expression Profiles	1.0	1.64105
causing	GeneRIF Biological Term Annotations	1.0	null
plasma membrane region	GO Cellular Component Annotations 2015	1.0	null
transporter	GeneRIF Biological Term Annotations	1.0	null
496100350_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12698
Perturb_483_KD_AFF1_SRP299901	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.56024
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.69211
BRD-K44227013_ponatinib_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92941
NPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30704
HuP-T3	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.86008
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20021
t47d	HPA Cell Line Gene Expression Profiles	1.0	1.20215
kasugamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03673
NCI-H1437	GDSC Cell Line Gene Expression Profiles	1.0	2.12869
ovary cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314409
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
Annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
biological_process	GO Biological Process Annotations 2015	1.0	null
Coma	CTD Gene-Disease Associations	1.0	1.43103
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47745
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.48351
Angioid Streaks	HuGE Navigator Gene-Phenotype Associations	1.0	null
Perturb_17190_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930938
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.236312
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24543
GTEX-R55G-1126-SM-48FDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932086
abnormal renal physiology	HPO Gene-Disease Associations	1.0	null
CHP-134	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929243
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PRODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76553
effect	GeneRIF Biological Term Annotations	1.0	null
Capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
placenta_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.29998
BRD-K15620114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86255
BRD-K20368781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05185
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.080491
BL4565 (KIF1B)	NURSA Protein Complexes	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6062
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34594
BRD-K98431828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23951
Liver Neoplasms	CTD Gene-Disease Associations	1.0	2.35149
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041211
BRD-K43298189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45831
Endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26684
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20801
HNF4A-19761587-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K31330911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40476
Myeloid Leukemia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K90366266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23417
Perturb_11440_KO_RB1/TP53_SRP253428	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.54084
KP-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.88855
specifically	GeneRIF Biological Term Annotations	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.864274
skin	GeneRIF Biological Term Annotations	1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	1.48624
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
Graves Disease	DisGeNET Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23682
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
leukotriene transport	GO Biological Process Annotations 2023	1.0	null
Interbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0606
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17357
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21927
BRD-K40838215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5345
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04895
abc transporters general	KEGG Pathways	1.0	null
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.883892
abnormal circulating lipoprotein level	MPO Gene-Phenotype Associations	1.0	null
Perturb_485_KO_ITGB1_SRP320563	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.73224
hss	GeneRIF Biological Term Annotations	1.0	null
amiloride-3990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.598
Fetal Growth Retardation	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8582123-13073_2021_996_MOESM4_ESM.xlsx-SATB1-HIT_SATB1	Rummagene Transcription Factor Associations 2026	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
Indomethacin	CTD Gene-Chemical Interactions	1.0	null
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982649
abnormal renal/urinary system morphology	MPO Gene-Phenotype Associations	1.0	null
COX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03022
Electrocardiogram Abnormal	DisGeNET Gene-Phenotype Associations	1.0	null
leukotriene transport	GO Biological Process Annotations 2025	1.0	null
mitral valve prolapse	HPO Gene-Disease Associations	1.0	null
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
drug-related genes	GAD Gene-Disease Associations	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045165
metabolic	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990098
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01642
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TAL1_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
having	GeneRIF Biological Term Annotations	1.0	null
BRD-K76401790_JNK-IN-5A_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0241
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09467
recurrent	GeneRIF Biological Term Annotations	1.0	null
Dizziness	CTD Gene-Disease Associations	1.0	1.06044
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.41885
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neutral	GeneRIF Biological Term Annotations	1.0	null
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96975
Cutis laxa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.351
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05466
telangiectasia	HPO Gene-Disease Associations	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF552	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21421
BRD-K42271016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60516
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
membrane region	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K59095205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39068
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
Artery wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.928
Lung adenocarcinoma_LUAD_TCGA-50-8457-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.84687
Cardiomyopathies	CTD Gene-Disease Associations	1.0	1.80548
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20745677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42378
high palate	HPO Gene-Disease Associations	1.0	null
BRD-K06772291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61915
BRD-K41396351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3569
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8702
provide	GeneRIF Biological Term Annotations	1.0	null
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.115716
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35125
establishment of localization	GO Biological Process Annotations 2015	1.0	null
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Glioma	CTD Gene-Disease Associations	1.0	1.02151
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53963
environmental	GeneRIF Biological Term Annotations	1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
BRD-K61718261_NCGC00182361-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT-112	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.02814
IFI6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42873
hsa-miR-4727-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Beta thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.139
NCIH508	CCLE Cell Line Gene Expression Profiles	1.0	1.60415
nordihydroguaiaretic acid-1223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
arterial	GeneRIF Biological Term Annotations	1.0	null
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876384
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.079105
reticular formation of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1247
Ventral aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
Retinal drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32838
CHONDROITIN SULFATES	DGIdb Drug Targets 2026	1.0	2.35253
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	1.0	3.70466
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.842982
BRD-K11671649_5-amino-1-ethyl-3-(naphthalen-1-ylmethyl)-1H-pyrazole-4-carbonitrile CAL-NCGC-061_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
17906199-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
retinoblastoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bone matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHH5	CCLE Cell Line Gene Expression Profiles	1.0	1.47274
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88806312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0052
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
subcutaneous hemorrhage	HPO Gene-Disease Associations	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05102
Inflammation	CTD Gene-Disease Associations	1.0	2.12565
literature	GeneRIF Biological Term Annotations	1.0	null
abnormality of the face	HPO Gene-Disease Associations	1.0	null
P-loop containing nucleoside triphosphate hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
VAChT_KD_GDS4325_361_mouse_Heart from C57BL/6 males	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADNP_Deficiency - NULL MUTATION_GDS2540_691_mouse_E9 embryos - Heterozygous mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.148013
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
hypermelanotic macule	HPO Gene-Disease Associations	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15573
BRD-K18094884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08101
X-linked dominant hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
only	GeneRIF Biological Term Annotations	1.0	null
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45753
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.95479
Calciphylaxis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.911
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32471
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-M30523314_V2264_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
sinusoidal	GeneRIF Biological Term Annotations	1.0	null
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.915489
intestinal tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.622183
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.99016
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51216
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.75759
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85649685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14931
Keratoconjunctivitis	DisGeNET Gene-Disease Associations	1.0	null
basolateral plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886392
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836335
BRD-K17140735_-666_T3M10_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inflammatory	GeneRIF Biological Term Annotations	1.0	null
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.486
BRD-K05804044_AZ-628_HT29_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868522
Yellow Papule	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K99660943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.591
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51364
SF-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.566
HCC1897	CCLE Cell Line Gene Expression Profiles	1.0	1.36548
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29776
Somatosensory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26958
streaks	GeneRIF Biological Term Annotations	1.0	null
Peau D'Orange Surface Of Breast	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97797
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07352
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the mitral valve	HPO Gene-Disease Associations	1.0	null
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.084
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAPK1_knockdown_145_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.33605
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41468
renal	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-OIZH-3026-SM-3NB1G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08012
detection	GeneRIF Biological Term Annotations	1.0	null
BRD-K41620124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6761
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.31362
cellular_component	GO Cellular Component Annotations 2015	1.0	null
mutants	GeneRIF Biological Term Annotations	1.0	null
FU97	CCLE Cell Line Gene Expression Profiles	1.0	2.20348
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8526
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16602
purine ribonucleoside triphosphate metabolic process	GO Biological Process Annotations 2025	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.07013
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51156
DJM-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.91988
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50303
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9405
ATM_Deficiency_GDS1544_769_mouse_Lymph nodes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cisplatin	HMDB Metabolites of Enzymes	1.0	null
BRD-A82590476_SDZ NKT 343_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967783
BRD-K49669041_BX-912_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3_OE_GDS3444_576_mouse_Cultured embryonic stem (ES) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856931
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53796
Y-27632-832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sf-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.313139
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal ocular fundus morphology	MPO Gene-Phenotype Associations	1.0	null
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02905
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Catalepsy	CTD Gene-Disease Associations	1.0	1.02262
Disease Models, Animal	CTD Gene-Disease Associations	1.0	2.88009
Acne	DisGeNET Gene-Disease Associations	1.0	null
BRD-K77483143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40804
Exanthema	CTD Gene-Disease Associations	1.0	1.50043
hepatoid	GeneRIF Biological Term Annotations	1.0	null
MSX1_01_281	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60923
cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911915
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11678
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2897
GSK3B_knockdown_208_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52791
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301398
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adenoma	CTD Gene-Disease Associations	1.0	1.38724
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.66792
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29152
enpp1	GeneRIF Biological Term Annotations	1.0	null
suggests	GeneRIF Biological Term Annotations	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
OUMS27	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12214
single-organism process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	1.0	1.4552
calcification of falx cerebri	HPO Gene-Disease Associations	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894543
BRD-K97377031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21513
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Arterial calcification	ClinVar Gene-Phenotype Associations 2025	1.0	null
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30653
BRD-K34482448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43802
Multi drug resistance-associated protein	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K25269762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02821
nucleus	GO Cellular Component Annotations 2015	1.0	null
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97449
abcc6p1	GeneRIF Biological Term Annotations	1.0	null
8-MG-BA	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.14186
ZFC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9783
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.18127
RCOR1	ChEA Transcription Factor Targets	1.0	null
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29338
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26565
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
fever	GeneRIF Biological Term Annotations	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.138
ATP metabolic process	GO Biological Process Annotations 2023	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-3673	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
monobenzone-6713	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
other	GAD High Level Gene-Disease Associations	1.0	0.298214
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC265	CCLE Cell Line Gene CNV Profiles	1.0	1.6823
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912932
TBP	ENCODE Transcription Factor Targets	1.0	null
Bilirubin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.829
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K39859838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53691
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21146
GSE237040_2_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
adenine nucleotide transport	GO Biological Process Annotations 2025	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20999
8-azidoadenosine 5'-triphosphate	CTD Gene-Chemical Interactions	1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15178
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63795
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
increased susceptibility to dystrophic cardiac calcinosis	MPO Gene-Phenotype Associations	1.0	null
Drug Hypersensitivity	CTD Gene-Disease Associations	1.0	1.39142
pseudoxanthoma elasticum	GAD Gene-Disease Associations	1.0	null
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
prochlorperazine-1640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
angioid	GeneRIF Biological Term Annotations	1.0	null
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.854
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62416
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71764
Lymphopenia	CTD Gene-Disease Associations	1.0	1.10493
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.15477
BRD-K26767475_NCGC00183255-01_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6258166__F6	PFOCR Pathway Figure Associations 2023	1.0	null
Anoxia	CTD Gene-Disease Associations	1.0	1.15324
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16697
cell part	GO Cellular Component Annotations 2015	1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Progeria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
Abnormality Of The Cerebral Vasculature	DisGeNET Gene-Disease Associations	1.0	null
Hepatitis	CTD Gene-Disease Associations	1.0	1.90869
Intraoperative Floppy Iris Syndrome	DisGeNET Gene-Phenotype Associations	1.0	null
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K68595406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31904
intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.114387
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867841
BRD-K44582497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05075
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877176
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
retinal drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.830689
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836368
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHH7	CCLE Cell Line Gene Expression Profiles	1.0	1.57546
SLR21	CCLE Cell Line Gene Expression Profiles	1.0	1.76479
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24082
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48072
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.069907
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
Prestwick-689-5816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Myocardial Ischemia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949707
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897168
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38913
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.938456
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58117
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55372
abnormal artery morphology	MPO Gene-Phenotype Associations	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32769
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88511
LAMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1029
Acute Myeloid Leukemia_LAML_TCGA-AB-3012-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931123
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
least	GeneRIF Biological Term Annotations	1.0	null
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15857
Sudden Cardiac Death	DisGeNET Gene-Phenotype Associations	1.0	null
PMC11401502-mmc1.pdf-11-TSHZ3_TSHZ3	Rummagene Transcription Factor Associations 2026	1.0	null
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26451
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pseudoxanthoma Elasticum	CTD Gene-Disease Associations	1.0	2.88009
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.503
retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.105456
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17459
primarily	GeneRIF Biological Term Annotations	1.0	null
Mammary Paget's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
haloperidol-983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Congenital Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05956
BRD-K64890080_BI-2536_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hi-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
modifying	GeneRIF Biological Term Annotations	1.0	null
neoplasm	HPO Gene-Disease Associations	1.0	null
BRD-A20213616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17826
BRD-K02407574_Parbendazole_A549_24.0_h_0.31_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the retinal vasculature	HPO Gene-Disease Associations	1.0	null
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54023
19266166-Table1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K20501114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83236
mineralization	GeneRIF Biological Term Annotations	1.0	null
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06751
spinal cord	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_UP-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53221607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49715
BRD-K04013642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55478
Transport of small molecules	Reactome Pathways 2024	1.0	null
BRD-K88583132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58413
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291365
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.057192
PANC1	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.363766
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63006
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06386
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1182
due	GeneRIF Biological Term Annotations	1.0	null
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pruritus	DisGeNET Gene-Phenotype Associations	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050143
BRD-K06344882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01594
arise	GeneRIF Biological Term Annotations	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01831
BRD-K90382497_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20636
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46773
Tectum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
abnormal vibrissa follicle morphology	MPO Gene-Phenotype Associations	1.0	null
NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K86492010_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07454
liver	HPA Tissue Gene Expression Profiles	1.0	1.10203
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.98855
15604263-Table2	GeneSigDB Published Gene Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
MDCK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.682
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12683
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.959235
macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20823
Blood platelet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.733
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943447
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.8931
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16401
BRD-K61742182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60833
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04815
BRD-K04853698_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.151261
BRD-K69396470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43006
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.336
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85615
conversion	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18717
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0566
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916107
CLPP_KO_GDS4791_377_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5184
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10809
BRD-K72602058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59047
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49644
BRD-K99749624_linifanib_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bromopride-2182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
showing	GeneRIF Biological Term Annotations	1.0	null
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.72864
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
AAA+ ATPase domain	InterPro Predicted Protein Domain Annotations	1.0	null
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28487
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32697
BRD-K88645787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70199
BRD-K23694339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49105
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.48864
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233731
total	GeneRIF Biological Term Annotations	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02998
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32697
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.849126
Thoracic aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5174-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5195
tretinoin-1049	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
german	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.988416
Etoposide	HMDB Metabolites of Enzymes	1.0	null
POLR1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3381
BRD-K29138092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16824
Colchicine Resistance	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1953
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14323
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263327
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874127
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5542
microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.147042
abnormal blood vessel morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-P4QT-2026-SM-3NMCJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56686
vision/eye phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K96788889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93148
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06211
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841909
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	2.17695
BRD-K73261812_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35588
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.63134
VPS26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11809
BRD-K75985122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35034
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.874437
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850449
HIV_Infected-mDC_None_GSE42058	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.31883
Acute Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
abnormal vascular physiology	HPO Gene-Disease Associations	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00308
arecoline-1303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane part	LOCATE Curated Protein Localization Annotations	1.0	null
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.45946
roles	GeneRIF Biological Term Annotations	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37433
H2AL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28258
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.921038
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8888
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47766
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.856053
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91977
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57496
Nape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
abnormality of thyroid physiology	HPO Gene-Disease Associations	1.0	null
CCDC74A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67881
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50778
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48536
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
carriers	GeneRIF Biological Term Annotations	1.0	null
ovary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181629
BRD-K99824630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31636
increased susceptibility to dystrophic cardiac calcinosis	MGI Mouse Phenotype Associations 2023	1.0	null
KLF7_KO_GDS2069_68_mouse_olfactory epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-A19037878_trichostatin A_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44753
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03326
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ALKBH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34428
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
phenotypes	GeneRIF Biological Term Annotations	1.0	null
impair	GeneRIF Biological Term Annotations	1.0	null
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.09234
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Vitamin K deficiency bleeding	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25684
PPP1R2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.663
scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.122203
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.88253
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.30482
abnormal retina morphology	MPO Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IS-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reduced bone mineral density	HPO Gene-Disease Associations	1.0	null
ABC-family proteins mediated transport	Reactome Pathways 2024	1.0	null
Abdominal aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K97839095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32868
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Blood plasma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.733
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
physiologic	GeneRIF Biological Term Annotations	1.0	null
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15847
granuloma annulare	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.399334
Spondylosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
SLC7A11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590536
Colorectal Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
french	GeneRIF Biological Term Annotations	1.0	null
heart	GeneRIF Biological Term Annotations	1.0	null
GSE237040_0_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal circulating hdl cholesterol level	MPO Gene-Phenotype Associations	1.0	null
GSE193177_1_v_2_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36438
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40713
SOX2	ChEA Transcription Factor Targets	1.0	null
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914159
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
nitrofural-6721	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08431704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29748
BRD-K99749624_linifanib_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K48276655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80803
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.913
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85211
metacycline-4062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K31408750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11859
GINS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22724
nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063464
BRD-K96353852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41895
TUHR4TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78576
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
regulatory	GeneRIF Biological Term Annotations	1.0	null
KU-19-19	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.23859
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
GSE190076_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K11741103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60254
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-FOS_mod_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
ECC12	GDSC Cell Line Gene Expression Profiles	1.0	1.89962
Hypophosphatasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.953
BRD-K76318449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08118
BRD-M86331534_BJM-ctd2-9_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAL1_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
irregular hyperpigmentation	HPO Gene-Disease Associations	1.0	null
SOCS3_DELETION_GDS1254_80_mouse_ES (embryonic stems cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prestwick-920-5056	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hyperlipidemias	CTD Gene-Disease Associations	1.0	1.65467
lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828088
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06891
GSE95688_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25293
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6B-Table_S6B_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_Type_II_LGG_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138019_4_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48092898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61736
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20093
under	GeneRIF Biological Term Annotations	1.0	null
pxe	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
icosanoid transport	GO Biological Process Annotations 2023	1.0	null
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.113347
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44516
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90279
lateral plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K49865102_PD-0325901_HEPG2_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4935