association dataset threshold value standardized value Perturb_12911_KD_MDC1_SRP313175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.52766 TIG3TD CCLE Cell Line Gene Expression Profiles 1.0 1.76975 AU565 DepMap CRISPR Gene Dependency 1.0 4.51522 Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0566 Perturb_11403_KD_CPT1A_SRP076884 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.4068 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Chanarin-Dorfman syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.846 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11205 LTBR_INHIBITION - 27 Day_GDS2005_731_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null phosphatidylserine metabolic process GO Biological Process Annotations 2023 1.0 null GSE206779_1_v_3_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null liminal part of the r9 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08446 Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23342 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.865869 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.16802 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7374_KO_MGA_ERP067388 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.1728 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null SW403 DepMap CRISPR Gene Dependency 1.0 4.45777 FAM117B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8026 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.26373 JHH2 CCLE Cell Line Gene Expression Profiles -1.0 -3.17138 EWS502 CCLE Cell Line Gene Expression Profiles 1.0 1.67303 periventricular stratum of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19587 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K36me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33503 POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PICALM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71893 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.24414 FXR MotifMap Predicted Transcription Factor Targets 1.0 null POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33815 GSE186483_6_v_4_lrrk2_mouse RummaGEO Gene Perturbation Signatures -1.0 null medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.3437 NCIH1105 CCLE Cell Line Gene Expression Profiles -1.0 -1.87069 posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32173 Perturb_6207_KD_TIFIA_SRP188861 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.48218 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19029 SKI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56816 KYSE30 Achilles Cell Line Gene Essentiality Profiles 1.0 1.08402 Entorhinal area, lateral part, layer 2b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11002 Perturb_2981_KD_ISG_SRP158414 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.54558 H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1409 periventricular stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02131 r1 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88126 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.843387 UMRC6 CCLE Cell Line Gene Expression Profiles 1.0 2.0763 catalytic activity GO Molecular Function Annotations 2015 1.0 null Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.3313 rostral interstitial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61402 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.909739 AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84765 EW8 CCLE Cell Line Gene Expression Profiles 1.0 1.53148 STAT3 MotifMap Predicted Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endometrium_8a HPA Tissue Sample Gene Expression Profiles 1.0 1.10871 Perturb_6424_KD_LOC646329_SRP220725 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.09135 GSE102675_3_v_0_atf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.39691 NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.850665 Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20466 Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.826454 PEO4 DepMap CRISPR Gene Dependency 1.0 3.22221 H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNU216 DepMap CRISPR Gene Dependency 1.0 2.68954 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.06086 rhombomere 9 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01656 Perturb_11435_KD_CIT_SRP173646 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.80322 Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07413 superficial stratum of r1Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.97912 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8491_KD_CGA/UCG_SRP119324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.57556 Aortic aneurysm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.585 HRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0096 head of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.837349 Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null phospholipase activity GO Molecular Function Annotations 2025 1.0 null Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.418 Cortical amygdalar area, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48862 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17085 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.4635 ZNF549 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.5714 Prostate cancer GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.53979 Perturb_10144_KD_STAU2_SRP216662 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.48078 monoacylglycerol lipase activity GO Molecular Function Annotations 2025 1.0 null NCIH647 CCLE Cell Line Gene CNV Profiles 1.0 1.53532 Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.87768 dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.906218 JIMT1 CCLE Cell Line Gene CNV Profiles 1.0 1.48463 lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03515 lateral posterior nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0628 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53238 AMO1 DepMap CRISPR Gene Dependency 1.0 2.2144 liminal part of alar p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27306 ventrolateral prefrontal cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.852577 Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.8388 Ooplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.685 CW-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8629-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2435_KD_TSHZ3_SRP072302 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.62305 temporal muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39556 OXSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83604 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20887 mantle zone of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3079 HCT 116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.898843 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_12_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_8352_KO_ADCY9_SRP320358 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.61527 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05729 NCI-H128 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_7830_KD_PREP1_SRP113380 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.69464 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16667 MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980285 CCK81 DepMap CRISPR Gene Dependency 1.0 4.2957 PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Gene_Name_ZNF217 Rummagene Transcription Factor Associations 2026 1.0 null H3K36me3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7069-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC70 DepMap CRISPR Gene Dependency 1.0 2.61395 496100651_FWM_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.22577 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07881 496100478_HIP_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30908 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.69907 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26626 Kidney Chromophobe_KICH_TCGA-KO-8414-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.935613 inner CP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01011 Perturb_7752_KD_YTHDF2_SRP155278 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.33181 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHARC syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.405 layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18816 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1995 smooth muscle HPA Tissue Gene Expression Profiles -1.0 -0.932518 Perturb_9545_KO_Ucp1_SRP187003 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.55457 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6804 POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE186810,GSE186813_3_v_5_furin_mouse RummaGEO Gene Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.48512 DBTRG-05MG COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100574_HIP_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.14353 Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70126 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28767 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null N4BP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29388 Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2360_KD_TSHZ3_SRP072302 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.57953 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8276_KD_UPF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.77435 H3K36me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCIAML3 Achilles Cell Line Gene Essentiality Profiles 1.0 1.87924 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.931519 salivary gland HPA Tissue Gene Expression Profiles 1.0 1.17888 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null monoacylglycerol catabolic process GO Biological Process Annotations 2025 1.0 null upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.45829 Perturb_6404_KO_ERBB_SRP118937 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.3365 Twist2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8894 Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46907 Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null H3K36me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2919-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ICC2 DepMap CRISPR Gene Dependency 1.0 2.37635 PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.60083 Perturb_14572_KO_EP300_SRP336466 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.33258 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.854128 superficial stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.69255 Medial group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55252 Perturb_8289_KD_NONO_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.60933 hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.21396 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.76131 SPI1-23547873-NB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null OVCA-420 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.357 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Secretory granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.985 ESR1_T47D_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null JVM-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null ACHN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.96329 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null Koelliker-Fuse subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.18681 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6906-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2760_KD_CBX3_SRP077334 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.02581 Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.3804 Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.33152 Perturb_8097_KD_SUCLG1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.01416 GSE162276_4_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08846 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.34712 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1538 inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.877877 Perturb_11961_KD_STAG2_SRP278638 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.48309 hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.996961 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.75193 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.36169 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23782 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3106 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.18868 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.927451 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.12105 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38007 H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.996189 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U7-06A-21R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null appendix HPA Tissue Protein Expression Profiles 1.0 0.898233 ATRFLOX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.0396 Inner acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.059 PDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00675 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07982 Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2156 SKN COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.0079 Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH716 CCLE Cell Line Gene CNV Profiles 1.0 1.4252 Perturb_15399_KD_RUVBL1_SRP361862 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.24 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.72869 TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4797 GSE144443_0_v_1_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null HOP62 DepMap CRISPR Gene Dependency 1.0 2.37829 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.96379 ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10523 Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.1491 Perturb_15385_KD_FGF13_SRP319157 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.28953 SUZ12_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EXD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43572 cell part LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me1_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.33898 Exocytic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.678 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8491 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0468 PBX1 ChEA Transcription Factor Targets 1.0 null Perturb_1318_KO_BATF_SRP201368 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.46868 intermediate stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30457 Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.1144 Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38115 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OAW42 Achilles Cell Line Gene Essentiality Profiles 1.0 1.02149 POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF Rummagene Transcription Factor Associations 2026 1.0 null H4K20me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-92-8065-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.45449 MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.945007 SETDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06791 POLR2A ENCODE Transcription Factor Targets 1.0 null LN319 Achilles Cell Line Gene Essentiality Profiles -1.0 -3.26474 CAL51 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.92856 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.4541 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65651 GSE247862,GSE247863_2_v_5_eomes_mouse RummaGEO Gene Perturbation Signatures 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42271 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UE-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.83487 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IM9 DepMap CRISPR Gene Dependency 1.0 3.30657 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8098_KD_TUFM_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.84484 rpmi8226 HPA Cell Line Gene Expression Profiles -1.0 -1.01148 NB13 DepMap CRISPR Gene Dependency 1.0 4.8308 GSE110268_1_v_3_foxd1_human RummaGEO Gene Perturbation Signatures -1.0 null NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.885593 phosphatidylserine metabolic process GO Biological Process Annotations 2025 1.0 null VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.92285 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8196_KD_TIAL1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.39586 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16667 PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null Medullary reticular nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3485 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.69279 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16122 Perturb_7661_KD_CTCF_SRP072272 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.61153 Perturb_8189_KD_HNRNPF_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.18874 Carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FTH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01361 endoplasmic reticulum LOCATE Predicted Protein Localization Annotations 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.71316 periventricular stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48547 Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7J0-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.05464 Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28101 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null HCC1187 CCLE Cell Line Gene CNV Profiles -1.0 -1.43683 NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61614 HS698T CCLE Cell Line Gene Expression Profiles -1.0 -1.95472 H3K36me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FKBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55283 SAP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02174 Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.22 GSE188870,GSE188871_1_v_5_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null inner SZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0418 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.901169 Sleep disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.622 Nr1h2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.4544 SF767 CCLE Cell Line Gene Expression Profiles 1.0 1.66357 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_6435_KD_HOXA10AS_ERP131886 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.5016 Perturb_10059_KD_XRN2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.62329 inner SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40322 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23719 CORL88 CCLE Cell Line Gene Expression Profiles -1.0 -1.54973 Perturb_3563_KD_HMGA1_SRP299065 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.54864 mantle zone of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10203 KELLY DepMap CRISPR Gene Dependency 1.0 2.04619 posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.905015 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2067 r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28714 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM19 CCLE Cell Line Gene CNV Profiles 1.0 2.02588 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -3.2562 NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57542 NASP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28812 KNS60 DepMap CRISPR Gene Dependency 1.0 2.49924 Perturb_13518_KD_ILF2_SRP077068 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.77007 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1463 CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.01376 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05975 GP2D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08646 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.841823 Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2496_KD_NXF1_SRP226431 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.35046 HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.04601 Perturb_14840_KD_GCM1_SRP358680 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.88065 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.22905 Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPS26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98974 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYOG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.0773 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Immune system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.982627 KASUMI1 CCLE Cell Line Gene Expression Profiles 1.0 1.72626 CHD7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.927374 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.35052 H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MM-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26165 r3 pontine raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2038 Perturb_14582_KO_NQO1_SRP217327 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.51128 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0598 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Alveolar cell type II TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.683 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB7 DepMap CRISPR Gene Dependency 1.0 2.23763 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10383 Perturb_8280_KD_DDX5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.93875 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19015 H4K20me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69214 Perturb_4212_KO_Mir140_SRP245562 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.83744 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.967366 cd8 cells HPM Cell Type and Tissue Protein Expression Profiles 1.0 1.12474 GSE221327_8_v_9_clpp_human RummaGEO Gene Perturbation Signatures -1.0 null RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.0298 H3K79me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.21911 subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2705 Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.3318 NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07763 Perturb_8212_KD_SMNDC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.96504 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.889011 CHL1 CCLE Cell Line Gene CNV Profiles -1.0 -2.14669 CCNT2 ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB17 DepMap CRISPR Gene Dependency 1.0 4.3503 Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01609 POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2814 CCLE Cell Line Gene Expression Profiles 1.0 2.0232 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.878634 posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.07749 E2F1 JASPAR Predicted Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null glycerophospholipid catabolic process GO Biological Process Annotations 2025 1.0 null mantle zone of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78432 Perturb_12730_KD_INCA1_SRP221667 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.10192 HES2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9443 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cuneate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.86006 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36148 SARS-CoV MA15_Day4-PFU-10^4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.78029 rh30 HPA Cell Line Gene Expression Profiles -1.0 -1.38583 Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30645 r1 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.97579 Hematologic cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 SPIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33099 inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.912222 Prostate cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 Geniculate group, ventral thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4124 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.953926 Brain Lower Grade Glioma_LGG_TCGA-S9-A7QZ-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.897278 KOPN8 CCLE Cell Line Gene Expression Profiles 1.0 1.39523 SPI1-23547873-NB4-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0746 MCF 10A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.23976 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.62322 cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07847 Aortic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.585 mantle zone of r1Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88201 Prostate disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 periventricular mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77808 Perturb_7315_KO_UPF3A_ERP130416 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.46071 DMS153 CCLE Cell Line Gene Expression Profiles -1.0 -2.14712 superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08028 Mediodorsal nucleus of the thalamus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20583 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.2626 Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.47105 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07881 GSE162276_4_v_3_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.887247 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU308 CCLE Cell Line Gene CNV Profiles -1.0 -1.73448 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57716 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.863717 HEL9217 CCLE Cell Line Gene CNV Profiles -1.0 -1.73601 PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC Rummagene Transcription Factor Associations 2026 1.0 null PITX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42503 WM2664 CCLE Cell Line Gene Expression Profiles -1.0 -1.62572 H3K36me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null UOK101 CCLE Cell Line Gene Expression Profiles 1.0 1.51527 cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.952991 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.98551 POLR2AphosphoS5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null acylglycerol catabolic process GO Biological Process Annotations 2025 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.99492 KLF5_KO_GDS3509_553_mouse_ES cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null 496100586_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.54062 POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6954-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.886712 inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.870793 Perturb_8190_KD_HNRNPU_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.97446 L3MBTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78113 PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Nearest_Ensembl_ZNF217 Rummagene Transcription Factor Associations 2026 1.0 null A2780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.15233 Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1 Rummagene Transcription Factor Associations 2026 1.0 null APLP2_KO_GDS4414_536_mouse_adult cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RBBP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91647 Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 Olig2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.8185 F36P Achilles Cell Line Gene Essentiality Profiles 1.0 1.01874 H3K36me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBK1_druginhibition_188_GSE53658 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.14296 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.868957 MADD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20274 posteroventral part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04088 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.890547 Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.68361 Foramen magnum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.024 Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.829475 upper dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33117 NR2C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2653 TE-9 COSMIC Cell Line Gene Mutation Profiles 1.0 null NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.275 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE270 CCLE Cell Line Gene Expression Profiles -1.0 -1.7933 r9 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39605 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.28032 phosphatidylserine catabolic process GO Biological Process Annotations 2023 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.77009 GSE160817_5_v_8_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.99458 posteroventral (inferior) parietal cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.927775 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4476 striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12626 Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acylglycerol lipase activity GO Molecular Function Annotations 2023 1.0 null Perturb_8493_KD_MBNL1_ERP115267 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.33017 Perturb_2506_KD_NXF1_SRP226431 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.58624 RH30 CCLE Cell Line Gene CNV Profiles -1.0 -1.44026 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29941 ECC12 CCLE Cell Line Gene Expression Profiles -1.0 -1.60395 C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.20325 THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.978 dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02054 JIMT-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 Perturb_6780_KD_MED12_ERP024018 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.0671 cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.42604 H3K36me3_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 Perturb_12492_KD_PELP1_SRP351131 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.73838 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33167 KASUMI1 DepMap CRISPR Gene Dependency 1.0 7.29413 ZNF816 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.3514 Adrenocortical carcinoma_ACC_TCGA-OR-A5L6-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCF7 CCLE Cell Line Gene CNV Profiles 1.0 1.60882 Perturb_8055_KD_IGF2BP3_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.2112 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.861046 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75G-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.997217 a2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.518 inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01864 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYSM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15671 C1QL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21239 lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06043 nucleus of the stria medullaris (prethalamic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.089 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13006 Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-520 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18808 H3K36me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6833_KD_CASC9_SRP182039 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.44172 Cortical amygdalar area, posterior part, medial zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.09947 KMH2 CCLE Cell Line Gene Expression Profiles -1.0 -1.911 Cortical amygdalar area, posterior part, medial zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19077 GSC cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.777 inner CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.935774 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5129 IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.915442 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23782 Lateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03789 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43851 PCDH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01604 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ME1 CCLE Cell Line Gene Expression Profiles 1.0 2.00182 NCIH838 Achilles Cell Line Gene Essentiality Profiles 1.0 1.31959 Lung adenocarcinoma_LUAD_TCGA-67-6216-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NMCG1 DepMap CRISPR Gene Dependency 1.0 2.15315 r10 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31118 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19015 GSE114992,GSE114993_4_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.30562 hel HPA Cell Line Gene Expression Profiles 1.0 1.09861 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1218 FBXL14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21048 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.899044 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.49283 Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29167 Bed nuclei of the stria terminalis, posterior division, transverse nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.07792 Perturb_317_KD_TP63_SRP353945 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.53267 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.9689 Lung squamous cell carcinoma_LUSC_TCGA-68-8250-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5342 Perturb_9972_KD_BCLAF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.65926 Alpha/Beta hydrolase fold InterPro Predicted Protein Domain Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47316 HCT-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.99515 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66393 GAL3ST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38584 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CFAP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3485 H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC56 CCLE Cell Line Gene CNV Profiles 1.0 1.5995 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65501 Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 143B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.859301 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02043 C16orf87 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01454 MAP1LC3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71337 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34101 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.62513 Perturb_15382_KD_FGF13_SRP319157 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.84467 r9 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50164 small intestine HPA Tissue Protein Expression Profiles 1.0 0.898233 HS766T CCLE Cell Line Gene CNV Profiles 1.0 1.9314 Perturb_17278_KO_Upf2_SRP038144 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.941972 NCIH1836 DepMap CRISPR Gene Dependency 1.0 2.86562 Perturb_8186_KD_DNAJC21_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.92261 mediodorsal nucleus of thalamus_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.38354 Perturb_8134_KD_FXR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.36838 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.03249 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10457 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null prostate HPA Tissue Gene Expression Profiles 1.0 0.988655 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14019 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893385 Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CE-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1419 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 Perturb_257_KD_KLF6_SRP150445 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.37353 MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 periventricular stratum of isBL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25165 Perturb_9285_KD_LMTK2_SRP276928 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.2524 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06994 Perturb_6786_Mut_KRAS_ERP122260 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.47512 modified amino acid catabolic process GO Biological Process Annotations 2025 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null ATP11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41444 NCDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64315 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.30461 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UMRC2 CCLE Cell Line Gene Expression Profiles 1.0 1.40804 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYOD1 ENCODE Transcription Factor Targets 1.0 null primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.6628 GSE129244_3_v_1_lmo2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_8195_KD_SMN1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.95593 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.908528 H3K36me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.936912 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.41305 POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12532_KO_SMARCA4_SRP324802 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.43961 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.50593 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.942871 Perturb_8197_KD_TRIM56_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.65406 NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -2.00482 MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.08242 primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.01607 HS 895.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.859884 Perturb_6706_KD_ELOA_SRP314942 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.96923 superficial stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0708 MKN7 CCLE Cell Line Gene CNV Profiles 1.0 1.62202 CAOV-4 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null monoacylglycerol metabolic process GO Biological Process Annotations 2023 1.0 null Cortical amygdalar area, posterior part, lateral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23113 COLO 800 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.935467 intermediate stratum of PThE Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.089 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26769 ZNF257 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.5167 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.76661 ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.1813 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RELA JASPAR Predicted Transcription Factor Targets 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893385 SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34512 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_7871_KD_PCF11_SRP258098 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.08516 Perturb_8092_KD_PUF60_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.36841 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.91194 MYC-22102868-BL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_15384_KD_FGF13_SRP319157 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.50875 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.11707 H2AFZ ENCODE Transcription Factor Targets 1.0 null Perturb_8059_KD_IGF2BP3_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.9674 Perturb_14093_KD_HDAC1_SRP199194 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.9913 NCIH1373 CCLE Cell Line Gene CNV Profiles -1.0 -1.37405 miR-142-3p_OE_GSE28456_470_human_Raji cells (B lymphocytes) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HARA DepMap CRISPR Gene Dependency 1.0 5.02043 POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Supramammillary nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49284 Entorhinal area, lateral part, layer 2a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40342 Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-SG-A849-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEC116 DepMap CRISPR Gene Dependency 1.0 2.20929 Cortical amygdalar area, posterior part, lateral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6997 Duodenal juice TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.986 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30803 Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.29756 Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.930434 Male reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 Dorsal nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92217 Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prethalamic eminence Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.089 Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89529 RHJT DepMap CRISPR Gene Dependency 1.0 5.71781 Perturb_6512_KD_ALKBH5_SRP090686 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.25836 SPI1_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_756_KO_DNMT1_SRP389363 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.07919 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0143 Bed nuclei of the stria terminalis, anterior division, fusiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52868 H3K36me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF3 ChEA Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41P-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.998507 H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null prostate_a HPA Tissue Sample Gene Expression Profiles 1.0 1.86953 MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84765 smoothmuscle_8b HPA Tissue Sample Gene Expression Profiles -1.0 -1.05781 H3K36me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72675 r1 part of intermediate nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07003 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.44904 Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4859 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14693 HMCB CCLE Cell Line Gene CNV Profiles -1.0 -1.98062 monoacylglycerol catabolic process GO Biological Process Annotations 2023 1.0 null Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17756 H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_2559_KD_U2AF2_SRP226431 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.89506 anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.18395 nucleus coeruleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42612 FUOM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.36677 ventral posterior parvicellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.11691 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DBTRG05MG DepMap CRISPR Gene Dependency 1.0 2.85264 Bed nuclei of the stria terminalis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.56788 WDR89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19429 Perturb_12130_KO_Ldb1_SRP136181 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.96119 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -3.55946 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893385 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.72705 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42273 Perturb_8230_KD_PUS1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.49358 Perturb_9955_KD_SF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.44434 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.870332 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-7020-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GH4-C1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.825 Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_7165_KD_FTH1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.82505 MAN2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89868 Midbrain raphe nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14696 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.85803 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HG-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.914541 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.874093 HCC1419 CCLE Cell Line Gene CNV Profiles 1.0 2.92584 Abdominal aortic aneurysm GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.809691 r4 part of pontine raphe cell population Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07784 Acute Myeloid Leukemia_LAML_TCGA-AB-2932-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus, descending division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37747 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UF-01A-23R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04252 LUDLU1 DepMap CRISPR Gene Dependency 1.0 2.29246 GPR120_KO_GDS4830_413_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NDUFA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26757 POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06148 Perturb_8057_KD_IGF2BP3_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PE/CA-PJ15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09695 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.945856 Pons, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18502 GSE139455_4_v_3_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null STRADB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24711 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.8345 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80893 CHD7 ENCODE Transcription Factor Targets 1.0 null EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.90623 mantle zone of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27373 centromedian nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12709 Postpiriform transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03382 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04782 496100631_PCx_dementia_TBI_77_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.17388 TLCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83439 dorsal septopreoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50164 r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00361 lipase activity GO Molecular Function Annotations 2023 1.0 null Perturb_15799_OE_EMP2_SRP265560 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.1931 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33935 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.862141 m1 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0566 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.963032 H3K36me3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.44933 HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.28703 HEY DepMap CRISPR Gene Dependency 1.0 2.05243 MYC ENCODE Transcription Factor Targets 1.0 null PMC4029819-pone.0098069.s006.xlsx-Sheet1-Table_S5_FSS_analysis_of_FOXA1_high_versus_FOXA1_low_cases_in_metastases_p-value_0_01_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null H357 DepMap CRISPR Gene Dependency 1.0 2.29146 periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28691 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.982225 hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.852908 H3K36me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPI1 ENCODE Transcription Factor Targets 1.0 null COLO775 CCLE Cell Line Gene CNV Profiles -1.0 -1.51342 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15692_KD_SLFN5_SRP051401 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.46319 NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.853671 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10029_KD_CELF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.3212 Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3087 MAN2C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49433 Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16731 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.905144 hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.37056 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16667 outer CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29515 Reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null HCT-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.923717 Perturb_8141_KD_MAGOH_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.1397 GSE139455_4_v_1_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.39465 Perturb_8143_KD_NCBP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.8806 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Usher syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.007 medial (magnocellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91395 POLR2A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8334_KD_HCF1_SRP178073 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.53276 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F5-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DOK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.901962 ADGRA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98945 MOLM13 DepMap CRISPR Gene Dependency 1.0 2.18664 Perturb_2733_KD_BCKDK_SRP298085 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.49505 medial part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10421 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PPARD ChEA Transcription Factor Targets 1.0 null PMC9580020-tx2c00131_si_003.xlsx-Fig_5A_data-HSF1_KOVAC_same_dataset_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null PNMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95078 Perturb_10035_KD_PUM1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.27435 Perturb_8755_KD_SON_SRP300475 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 HS706T CCLE Cell Line Gene Expression Profiles -1.0 -2.01535 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Hematopoietic system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 Mature chylomicron COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.294 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null central part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09447 Perturb_4911_KD_ATF7IP_SRP156289 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.17661 K562 Achilles Cell Line Gene Essentiality Profiles 1.0 1.38792 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6841 POLR2AphosphoS5_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.45289 mantle zone of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03033 Perturb_9131_KD_PPP2R2A_ERP121420 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.60972 III, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.26741 AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01736 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.919537 Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Atf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.9541 Perturb_8194_KD_SAFB2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.2369 WM88 CCLE Cell Line Gene Expression Profiles -1.0 -1.63978 Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PXR (PXR:RXR) MotifMap Predicted Transcription Factor Targets 1.0 null Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 77.1796 496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.78242 496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.00661 NCIH1734 CCLE Cell Line Gene CNV Profiles -1.0 -1.38233 Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE149903_4_v_1_myd88_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LMNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25907 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.21368 POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16667 vertical nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1087 skin_5e HPA Tissue Sample Gene Expression Profiles -1.0 -0.88354 Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884324 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.908528 ZFP28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79605 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.868937 ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16876 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.4002 orbital frontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17569 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01064 CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100629_HIP_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1369 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.30321 SUM 159PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.39889 Bed nuclei of the stria terminalis, posterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22675 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.873717 Perturb_12339_KD_SAM68_SRP230812 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.67503 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40064 Subgeniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35968 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.37178 HEL CCLE Cell Line Gene CNV Profiles -1.0 -1.35146 SULT2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87832 LRRC8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38214 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13939 GSE220914_1_v_0_zdhhc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.12346 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.2977 OARD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53019 Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_13655_KO_TAPR1_SRP291201 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.51774 KNS81 DepMap CRISPR Gene Dependency 1.0 2.93494 Perturb_10039_KD_UBE2L3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.78571 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03976 smoothmuscle_8a HPA Tissue Sample Gene Expression Profiles -1.0 -0.888102 Perturb_3178_KO_KDM1A2a_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.74881 NOTCH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86416 MYC_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 UACC893 CCLE Cell Line Gene CNV Profiles 1.0 1.39075 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74774 r2 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27056 UBLCP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69685 orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.914623 substantia innominata/basal nucleus, transitional part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22615 KDM5B ENCODE Transcription Factor Targets 1.0 null Perturb_10008_KD_HNRNPU_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.35423 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22161 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A204 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.29449 JURKAT CCLE Cell Line Gene Expression Profiles -1.0 -1.74478 NCIH716 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.46344 HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15144 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null hl60 HPA Cell Line Gene Expression Profiles 1.0 1.16041 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.826024 Brain Lower Grade Glioma_LGG_TCGA-S9-A6UB-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE188870,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null SPAG9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60593 Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SALE CCLE Cell Line Gene Expression Profiles 1.0 1.85535 Perturb_10212_KD_SETX_SRP353945 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.37744 Koelliker-Fuse nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49625 oculomotor nucleus, main part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1087 monoacylglycerol metabolic process GO Biological Process Annotations 2025 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null CHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.82748 layer 1 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16001 pc3 HPA Cell Line Gene Expression Profiles 1.0 2.50809 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.951445 PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF Rummagene Transcription Factor Associations 2026 1.0 null primary motor cortex (area M1, area 4)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0233 H3K36me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2076_OE_PUM1_SRP072710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.14096 RUNX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29435 SNU1197 CCLE Cell Line Gene Expression Profiles -1.0 -2.19066 EPHA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1445 CTPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37441 caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.936515 Perturb_15796_KD_EMP2_SRP265560 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8095_KD_SLBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.63301 Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8047_KD_MCRS1_SRP103083 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.6813 Lung adenocarcinoma_LUAD_TCGA-55-8087-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1345_KD_ARID1A_SRP336358 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.26509 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.889359 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.829674 Perturb_3177_KO_KDM1A2a_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.16748 medial part of the isB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02629 HCC44 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.02437 Perturb_3908_KD_ALDH1A1_SRP164778 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.01942 Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Artery disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.585 Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.3278 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_3913_KD_Y14_SRP118481 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.2933 Cortical amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34444 Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70885 F5 CCLE Cell Line Gene Expression Profiles 1.0 1.34843 Cortical amygdalar area, posterior part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55835 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.01773 HT144 CCLE Cell Line Gene CNV Profiles 1.0 1.60882 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09307 MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2827_OE_ERK1_SRP064353 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.38292 H3K36me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB157 DepMap CRISPR Gene Dependency 1.0 3.03653 SPI1 ChEA Transcription Factor Targets 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CORL24 CCLE Cell Line Gene Expression Profiles -1.0 -1.8912 H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32916 MCC26 DepMap CRISPR Gene Dependency 1.0 4.02446 Perturb_8431_KD_macroH2A1_SRP199287 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.44727 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.911403 thp1 HPA Cell Line Gene Expression Profiles -1.0 -1.02029 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.69927 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.25812 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10114_KD_NCBP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.88878 Perturb_10056_KD_SUPV3L1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.49304 ERF::NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.2395 external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.83928 Intermediodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00889 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03868 Metabolite levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC1 ENCODE Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7164_KD_FTH1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.08877 Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.909899 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27063 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44907 voltage-gated calcium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.548 FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8846 Prostate carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 Ichthyosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.207 AMIGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08253 ATF3-23680149-GBM1-GSC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01015 GSE132759_4_v_5_fgfr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null retroreuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.2944 CTCF ENCODE Transcription Factor Targets 1.0 null HEKTE CCLE Cell Line Gene Expression Profiles 1.0 1.43309 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ECC4 DepMap CRISPR Gene Dependency 1.0 3.00841 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9883_KD_CPEB4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.92077 NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.9248 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.97782 Williams-Beuren syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.199 TM31 CCLE Cell Line Gene CNV Profiles -1.0 -1.74724 A673 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.11486 Alpha/beta hydrolase fold-5 InterPro Predicted Protein Domain Annotations 1.0 null SW872 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K36me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.996312 pregeniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97754 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE172016_2_v_1_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 3.4047 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50276 Perturb_10182_KD_RAD21_SRP225887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.98682 Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47175 Perturb_8096_KD_SRSF5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.22942 ZNF384 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE118617,GSE118619_0_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hydrolase activity GO Molecular Function Annotations 2015 1.0 null pyramidal layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.56285 Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04022 Perturb_15026_KD_KLF11_SRP267336 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.91981 SLR24 Achilles Cell Line Gene Essentiality Profiles 1.0 1.12243 Perturb_7670_KD_HNRNPK_SRP111756 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.31646 mediodorsal nucleus of thalamus_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30593 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33407 Cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.585 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2347 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.50126 JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.3108 Mediodorsal nucleus of the thalamus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73122 Perturb_15383_KD_FGF13_SRP319157 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.51204 H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7 Rummagene Transcription Factor Associations 2026 1.0 null Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.59367 GCIY CCLE Cell Line Gene CNV Profiles -1.0 -1.74648 GATA2 ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3858 CAL51 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Calcium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.489 dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.88052 Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBXIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02043 Perturb_344_OE|KD_SMAD1|GDF6_SRP076553 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 KYSE140 CCLE Cell Line Gene CNV Profiles -1.0 -1.60257 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.192 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.836704 Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13075 Perturb_14285_OE_YAPS127A_SRP336792 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.32424 skeletal muscle HPA Tissue Protein Expression Profiles 1.0 0.898233 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04523 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.2001 Perturb_8185_KD_DNAJC2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.9522 Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HS-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CD79B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90974 MT-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Perturb_12635_KD_SPANX_SRP236602 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.39088 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.969757 Fbxl10_OE_GDS4788_580_mouse_fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_10211_KD_TP63_SRP353945 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.5636 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M4-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF213 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 70.7453 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.857898 Perturb_8091_KD_NOL12_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.36454 ATRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02826 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.18086 H3K36me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11271 stomach HPA Tissue Gene Expression Profiles 1.0 1.8251 non-Hodgkin lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.876624 SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.12511 Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_16813_OE_HNF1A/FOXA3/PROX1/SIRT1/PGC1A/AMPK_SRP167105 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.63576 Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC-25 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.51343 PC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null duodenum_4c HPA Tissue Sample Gene Expression Profiles 1.0 1.24983 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WI-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2473_KD_H2AZ1_SRP214665 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.3223 Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74857 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AX-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15798_KD_EMP2_SRP265560 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_3881_OE_HLAC_SRP363812 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.2498 Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57087 POLR2AphosphoS5_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1604 Perturb_38_KD_ATRX_SRP308220 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.85976 PSN1 CCLE Cell Line Gene CNV Profiles 1.0 1.32944 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.900138 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12738 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.4962 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.48108 Medullary reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51966 GSK3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48169 Sarcoma_SARC_TCGA-DX-A6BB-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intergeniculate leaflet of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47151 Nape TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.132 substantia innominata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08292 RAP1GAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37367 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.03476 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.0 PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_18_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.947274 GSE199606_1_v_4_csf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17883 PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_9958_KD_SUGP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.2795 SR786 CCLE Cell Line Gene CNV Profiles 1.0 1.56465 Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03535 MYC ChEA Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.58634 SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.22436 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.85185 ZNF564 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84123 GSE157777_1_v_0_foxa3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE188870,GSE188871_1_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2836_KD_MDC1_SRP313175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.60209 glycerophospholipid catabolic process GO Biological Process Annotations 2023 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08294 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34438 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null u698 HPA Cell Line Gene Expression Profiles 1.0 1.18568 MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.45764 RERF-LC-MS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.41968 GSE65617_0_v_4_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49724 gallbladder HPA Tissue Protein Expression Profiles 1.0 0.898233 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.947965 HMGN3 ENCODE Transcription Factor Targets 1.0 null phosphatidylserine catabolic process GO Biological Process Annotations 2025 1.0 null PPID CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18477 mantle zone of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34131 Perturb_7231_KD_UPF1LL_SRP295982 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.29051 primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.826892 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34232 GSE213632_3_v_5_acod1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Ventral posterolateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27464 NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43024 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.50335 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06348 POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3273 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03551 primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08748 MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20778 mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.2853 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null trochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.93891 TCCSUP Achilles Cell Line Gene Essentiality Profiles -1.0 -1.23989 Lymphatic system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 orbital frontal cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.95874 Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL-51 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.920077 Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial amygdala, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50624 COQ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73815 HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.59285 Perturb_11530_KD_THOR_SRP121007 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.3612 superficial stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87237 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null MKN74 CCLE Cell Line Gene CNV Profiles -1.0 -3.01882 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.28978 Lymphatic system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 rectum_8a HPA Tissue Sample Gene Expression Profiles 1.0 1.08398 OCIMY5 DepMap CRISPR Gene Dependency 1.0 2.40444 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00858 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14855 23132/87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.845208 nucleus subputaminalis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08656 Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74433 Lung squamous cell carcinoma_LUSC_TCGA-56-8628-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HM-01A-12R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MM485 DepMap CRISPR Gene Dependency 1.0 5.06309 ntera2 HPA Cell Line Gene Expression Profiles 1.0 1.01163 GSE186483_1_v_4_lrrk2_mouse RummaGEO Gene Perturbation Signatures -1.0 null UACC-893 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.827985 Perturb_15118_KD_DNMT3A_SRP054246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 16.1921 GSE186810,GSE186813_3_v_5_furin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bed nuclei of the stria terminalis, anterior division, oval nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62376 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08846 GSE226316_11_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures -1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Pallidum, caudal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.56788 Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3249 DOK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48521 PUR1 MotifMap Predicted Transcription Factor Targets 1.0 null intermediate stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33117 Perturb_9959_KD_SUPT6H_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.85428 BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9227 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21933 Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HDAC6 ENCODE Transcription Factor Targets 1.0 null H3K36me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.133 retromammillary area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30457 Elf5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.9481 Perturb_9636_KO_AR_SRP228794 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.31039 Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC15 CCLE Cell Line Gene CNV Profiles -1.0 -1.98215 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.909474 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21098 FRTL-5 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.636 Shs TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.534 NEK9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69767 GSE132759_4_v_2_fgfr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF449 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9688 PMC7339813-Supplementary_Data2.docx-59-ZBTB46_ZBTB46 Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.51967 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.872993 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.853035 superficial stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39166 Synaptic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.68 ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2169 RELT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74122 EBF1 ENCODE Transcription Factor Targets 1.0 null stratum pyramidale of rostral CA3 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.987833 GATA3_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A2058 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84765 ROS50 DepMap CRISPR Gene Dependency 1.0 5.80913 posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.838403 Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.9961 MSX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8096 Abdominal aortic aneurysm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.585 POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.956694 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.980321 bronchus HPA Tissue Protein Expression Profiles 1.0 0.898233 Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pallidal septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57583 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null thalamic (p2) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06523 mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.901527 smallintestine_4a HPA Tissue Sample Gene Expression Profiles 1.0 0.895368 r2 part of nucleus subcoeruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19842 Perturb_8200_KD_FUBP3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.49552 lateral part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34131 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9568 lung_3f HPA Tissue Sample Gene Expression Profiles 1.0 1.24535 Perturb_8841_KO_PSMA3_SRP281428 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.69707 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.854438 Cortical amygdalar area, posterior part, medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43351 anteroventral part of alar thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14121 mediodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33884 HS683 Achilles Cell Line Gene Essentiality Profiles 1.0 1.72529 Perturb_710_KO_DNMT1_SRP389363 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.41457 Reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11871 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.933816 H3K36me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.874093 MM386 DepMap CRISPR Gene Dependency 1.0 5.87251 amygdaloid complex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.41305 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.849427 POLR2AphosphoS5_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A1207 Achilles Cell Line Gene Essentiality Profiles 1.0 2.75395 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.136 Marginal zone lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7581777-41419_2020_3029_MOESM6_ESM.xlsx-MNX1_ChIP-Symbol_MNX1 Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.942199 spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19851 SAP30 ENCODE Transcription Factor Targets 1.0 null H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.00283 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1819 SK-MEL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.15398 496100573_HIP_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.22772 ESO51 DepMap CRISPR Gene Dependency 1.0 3.06475 HES1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7155 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.54909 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49115 SUDHL8 DepMap CRISPR Gene Dependency 1.0 2.8136 ZNF708 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.1543 Perturb_638_KD_GATA3_SRP372594 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.04398 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-861-ENSG00000130700_GATA5 Rummagene Transcription Factor Associations 2026 1.0 null magnocellular (medial) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02089 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42454 intermediate stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31775 posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.44913 SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null peduncular nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95922 H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_9966_KD_SF3A3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.85392 primary motor cortex (area M1, area 4)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17439 Perturb_8840_KO_AKIRIN2_SRP281428 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.51041 external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35968 POLR2AphosphoS5_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.982615 enzalutamide_homo sapiens_gpl570_gse44905 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null intermediate stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04651 HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.40048 NCI-H187 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.99018 intermediate isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76038 HEY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27212 PLOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85513 H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SH-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20921 lateral septal nucleus, intermedio-intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29798 Medial amygdalar nucleus, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04114 SLR20 CCLE Cell Line Gene Expression Profiles 1.0 1.83922 Perturb_394_KO_FOXM1_SRP272209 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.97281 MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2605 Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.0381 mantle zone of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06365 SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949999 V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.98364 Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03423 POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0204 Perturb_2779_OE_ACF7_SRP109301 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.93846 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00723 ISOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94197 PROX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56769 CEBPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1352 POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles 1.0 1.33743 H3K36me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8206-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12337_KD_TFEB_SRP226507 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.92755 496100626_FWM_no dementia_TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.36235 GB1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.20747 GP5D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null TAL1 ENCODE Transcription Factor Targets 1.0 null Perturb_7309_KD_IER3AS1_SRP348787 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2327 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7776_KD_C1QTNF1AS1_ERP112231 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.39921 MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2671 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.97222 posteromedial cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33006 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null molecular layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.835206 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-412-GATA5_GATA5 Rummagene Transcription Factor Associations 2026 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null Perturb_12239_KO_ZMYND8_SRP130942 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.09289 Central medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13224 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.988176 SETDB1 ENCODE Transcription Factor Targets 1.0 null NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.41334 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0221 H3K36me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.860325 GSE172247,GSE172250_0_v_2_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100611_FWM_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30348 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A652-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null D423MG DepMap CRISPR Gene Dependency 1.0 2.19634 Perturb_8093_KD_PUM1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.37544 UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998751 PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.68353 Male reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cochlear hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.971 PMC7595190-41598_2020_75453_MOESM6_ESM.xlsx-MLL_EFS_groups_DEGs-Symbol_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null paracentral lobule, posterior part, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.945416 Perturb_13390_OE_NSD2_SRP199225 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.9744 Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.622 VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30381 KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.697634 GSE235066_7_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null intermediate stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39605 OVTOKO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null DNAJA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1059 Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MB1 DepMap CRISPR Gene Dependency 1.0 4.74561 ZKSCAN5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.7436 PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.7864 DUSP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31864 M14 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100613_TCx_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.39415 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02189 Duodenum Mucosa Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.911824 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.96329 Perturb_8138_KD_IGF2BP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.43044 Perturb_7623_KD_UPF1LL_SRP295982 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.1122 Stomach Smooth Muscle Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.900938 HOXC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03952 rectum HPA Tissue Protein Expression Profiles 1.0 0.898233 CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null lung_4a HPA Tissue Sample Gene Expression Profiles 1.0 0.918381 Prostate adenocarcinoma_PRAD_TCGA-XJ-A83F-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1897 CCLE Cell Line Gene Expression Profiles 1.0 1.70464 Tbx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.7828 ZNF384_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4395-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE160083,GSE160084_2_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS21BM CCLE Cell Line Gene CNV Profiles -1.0 -2.57387 POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.972182 Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14698 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67503 Cell type cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8181_KD_XPO5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.83479 KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27063 ZNF365 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67613 Perturb_15343_KD_PGR_SRP223388 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.90382 Perturb_11426_KD_PRMT1_SRP357238 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.66673 Brain Lower Grade Glioma_LGG_TCGA-DH-A669-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OSR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6844 Principal sensory nucleus of the trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78466 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR Rummagene Transcription Factor Associations 2026 1.0 null r2 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.69255 H3K9me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventral isthmic part of dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77808 carboxylic ester hydrolase activity GO Molecular Function Annotations 2025 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null endometrium_8b HPA Tissue Sample Gene Expression Profiles -1.0 -1.02023 P3HR1 CCLE Cell Line Gene Expression Profiles 1.0 1.44361 MYOG ENCODE Transcription Factor Targets 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.56535 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.96629 central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.992801 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.882259 JHOS2 CCLE Cell Line Gene CNV Profiles 1.0 2.63774 GSE113221,GSE113968_4_v_1_prdm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null Perturb_10181_KD_CTCF_SRP225887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.1408 SOX12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8906 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.912084 HS695T CCLE Cell Line Gene CNV Profiles 1.0 1.46167 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.73471 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09097 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5749 Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-55 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.996189 Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DQ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral posterior lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.988367 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26651 Bed nuclei of the stria terminalis, anterior division, anteromedial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5611 Perturb_8287_KD_DDX55_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.94489 hippocampus (hippocampal formation)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.99322 r8 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2119 HT-144 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10853 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3750_KD_NORAD_SRP149071 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.61344 GATA2_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null intergeniculate leaflet Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43928 PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null ANKRD13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59421 CP66-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null MZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46798 CH157MN CCLE Cell Line Gene Expression Profiles 1.0 2.56907 B-cell lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.69883 Perturb_6707_KD_ELOA_SRP314942 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.80131 PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GSE114992,GSE114993_7_v_11_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.977 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02861 TAL1_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PNMA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69298 ESR1 ENCODE Transcription Factor Targets 1.0 null GATA2_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null NCIH1573 DepMap CRISPR Gene Dependency 1.0 3.64367 NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null H3K36me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRD5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02544 FERD3L JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9999 KYSE410 DepMap CRISPR Gene Dependency 1.0 3.33649 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19283 MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.61225 Perturb_14629_KO_MSLN_SRP199242 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.45497 Eosinophilic variant of chromophobe renal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.539 Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78068 lateral part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31118 dorsolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22579 r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08001 Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5861 p2 portion of the parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32788 DMS79 CCLE Cell Line Gene Expression Profiles -1.0 -1.60422 KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.10814 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6516-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paraventricular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15191 Perturb_9973_KD_CSTF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.67882 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.0259 PK59 CCLE Cell Line Gene CNV Profiles 1.0 1.85741 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.7269 GSE139455_4_v_6_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null Fbxl10_OE_GDS4788_327_mouse_MEF fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_13919_KD_TARDBP_SRP295809 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.30858 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4524 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PB-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Aa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.461 POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null carboxylic ester hydrolase activity GO Molecular Function Annotations 2023 1.0 null ESR1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RXRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.0334 TE1 CCLE Cell Line Gene CNV Profiles 1.0 1.37362 primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.73885 Npas2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.3056 colonrectum_f HPA Tissue Sample Gene Expression Profiles 1.0 0.943894 Perturb_9942_KD_NAA15_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.41716 mantle zone of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0822 periventricular stratum of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59517 biological_process GO Biological Process Annotations 2015 1.0 null CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.41288 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8129_KD_DDX3X_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.3351 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07828 intermediate tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08347 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I9-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8046_KD_MCRS1_SRP103083 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.7806 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40917 HDAC2 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A53L-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18854 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null DOLPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23042 Perturb_8193_KD_PPIL4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.37353 H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.963931 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.14752 SNU668 DepMap CRISPR Gene Dependency 1.0 4.06799 POLR2A_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5944-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1419 DepMap CRISPR Gene Dependency 1.0 3.79911 Bed nuclei of the stria terminalis, anterior division, anterolateral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85727 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_8282_KD_BCCIP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.28032 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86586 Perturb_15391_KD_CHD6_SRP399677 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.78185 Female reproductive endometrioid cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.226 Perturb_2734_KD_BCKDK_SRP298085 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.26717 Perturb_12905_KD_MDC1_SRP313175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.72682 molecular_function GO Molecular Function Annotations 2015 1.0 null H3K4me1_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dorsolateral isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72 dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07847 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OV90 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.10731 r7 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11808 PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null NR4A2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6577 RC-K8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.843616 intermediate stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50164 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal motor nucleus of the vagus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09658 NCIH2887 DepMap CRISPR Gene Dependency 1.0 3.34486 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.977096 Perturb_10233_KO_RN7SK_SRP201495 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.71906 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.845208 SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18566 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31174 GSE221327_8_v_0_clpp_human RummaGEO Gene Perturbation Signatures -1.0 null Neurod2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.5595 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7609 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17569 metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_14574_KO_EP300_SRP336466 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.70826 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.867802 Perturb_6434_KD_HOXA10AS_ERP131886 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.52368 CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2221 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6012 PKP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46936 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.62447 H3K36me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.0 ZNF175 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30722 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03505 H3K36me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.83378 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37415 TAL1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28916 TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.69681 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.894058 Perturb_8060_KO_TP53_SRP182675 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.77549 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.0306 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885952 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.75441 SPI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE213996_1_v_0_fhl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30395 Perturb_2495_KD_ALYREF/DDX39A_SRP226431 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.61956 PMC9174176-41467_2022_30924_MOESM6_ESM.xlsx-OC2-SYMBOL_ONECUT2 Rummagene Transcription Factor Associations 2026 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Abdominal aorta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.85 PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null G401 CCLE Cell Line Gene Expression Profiles -1.0 -1.53232 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03937 superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49724 MIEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40394 primary auditory cortex (core)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04736 HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.39931 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.841435 Parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06632 Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4706-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.929022 SUZ12 ENCODE Transcription Factor Targets 1.0 null CACO-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.935734 Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08897 Perturb_3894_KO_Lonp1_SRP301760 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.7423 NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 1.36358 H3K36me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFO-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.09782 Bed nuclei of the stria terminalis, posterior division, principal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14698 SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04956 Perturb_2794_KD_PSMD2_SRP173284 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.54013 SK23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884324 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null VIIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3217 posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.12847 Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.02102 Perturb_6423_KD_LOC646329_SRP220725 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.73213 Perturb_7163_KD_CD81_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.1226 GSE139455_4_v_5_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null Sarcoma_SARC_TCGA-X6-A8C6-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.36503 ventrolateral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20654 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.05675 Perturb_3622_KO_SMARCC2_SRP127343 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.00009 Perturb_8236_KD_PTBP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.12545 MKKS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25097 Perturb_9970_KD_WDR43_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.43024 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null Perturb_9961_KD_YTHDC2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.44759 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6442_KO_RHO_SRP134183 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.38976 zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06413 H3K36me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null RKO-E6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.42928 Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.87018 Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAKI2 DepMap CRISPR Gene Dependency 1.0 4.63484 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15665 TC-71 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.41651 GRB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6747 Bed nucleus of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15965 Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RASSF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75948 intermediate stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35571 Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE240468_3_v_2_nfyc_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null prethalamic (p3) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33212 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11346 Ventral part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40442 Perturb_1350_KD_NSUN2_SRP212699 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.8436 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.895488 SUIT2 DepMap CRISPR Gene Dependency 1.0 3.17625 DEOC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.924775 myc_17159920_cancer_cell_lines_lof_human_gpl570_gds2526 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.491843 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12513 ZNF281 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 160.26 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01122 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16171 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08265 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16667 p1 portion of the paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00532 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998751 LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5061 Perturb_8166_KD_CNOT7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.89642 ventral posterolateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14693 496100641_PCx_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19712 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1482 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.35052 LN428 CCLE Cell Line Gene Expression Profiles 1.0 1.61902 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12754 CTCF_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7248_KO_LEF1_ERP109990 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.0619 HCC44 DepMap CRISPR Gene Dependency 1.0 3.6777 FHL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26441 Ventral posteromedial nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49151 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.70519 lateral septal nucleus, intermedio-ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30457 inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21895 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Anteromedial nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0204 SMIM26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26325 outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.58521 ventrolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.32832 mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06148 H3K36me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of PThE Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.089 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23863 SKRC31 CCLE Cell Line Gene Expression Profiles 1.0 1.44721 salivarygland_6b HPA Tissue Sample Gene Expression Profiles 1.0 1.39317 mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02674 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.05914 H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null periventricular stratum of DTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53007 POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01842 Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RK-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC Rummagene Transcription Factor Associations 2026 1.0 null r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0083 CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.845208 CHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.88796 Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBB_KO_GDS3906_491_mouse_Testis - 7 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null STAT4 ChEA Transcription Factor Targets 1.0 null Perturb_7662_KD_CTCF_SRP072272 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.26453 H3K36me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.897722 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.29442 DFCI024 CCLE Cell Line Gene Expression Profiles 1.0 1.55923 PA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.16802 Perturb_8031_KD_PURPL_SRP383476 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.54632 SNU840 CCLE Cell Line Gene Expression Profiles -1.0 -1.9539 lipase activity GO Molecular Function Annotations 2025 1.0 null Perturb_531_KD_NKX22_SRP234742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.51466 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3848_KD_lncRNAAK096729_SRP192850 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.3079 POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.93698 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9799 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMED9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85557 periventricular stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76038 NR2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3379 Bed nuclei of the stria terminalis, anterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17602 NCIH854 CCLE Cell Line Gene CNV Profiles 1.0 1.5991 cellular modified amino acid catabolic process GO Biological Process Annotations 2023 1.0 null Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.205 primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.897927 hypotonia-cystinuria syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.256 p3 portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47175 UNC5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02985 NAMALWA CCLE Cell Line Gene Expression Profiles 1.0 1.463 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.90801 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6945-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.5827 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_16497_KO_MESP2_SRP153048 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.21985 Leydig cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.107 Perturb_15502_KD_GUCY1A1_SRP148609 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.04128 GSE199606_1_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures 1.0 null inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.881294 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08665 primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68455 Perturb_15401_KD_MELK_SRP098926 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.23106 HT-144 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.43617 NCIH520 CCLE Cell Line Gene CNV Profiles -1.0 -1.43578 Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM104B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93448 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.4788 r10 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35212 SLR26 CCLE Cell Line Gene Expression Profiles 1.0 2.11632 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15782 Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acylglycerol catabolic process GO Biological Process Annotations 2023 1.0 null NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0893 SIRT3_KO_GDS4817_416_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE116242_0_v_1_olig2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K36me3_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14577_KO_NQO1_SRP217327 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.34363 Perturb_11936_KD_SMARCD1_ERP132117 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.45304 Perturb_8177_KD_RPS3A_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.93543 VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10945 H2AC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99894 NELFE ENCODE Transcription Factor Targets 1.0 null Perturb_7149_KD_HBS1L_SRP070129 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.52738 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.45977 GSE134316_1_v_0_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.884873 CAOV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11274 superficial stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64843 Mediodorsal nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4124 H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.899877 inferior olivary complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08929 Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.26451 POLR2AphosphoS2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.585 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phospholipase activity GO Molecular Function Annotations 2023 1.0 null Cortical amygdalar area, posterior part, lateral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.72938 RKN CCLE Cell Line Gene CNV Profiles 1.0 1.34014 Perturb_13496_KD_IGF2BP1_SRP252425 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.03418 outer CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.867447 ZFP14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 81.5239 Perturb_13495_KD_IGF2BP1_SRP291710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.91917 VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39242 COLO205 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.1445 NCIH2171 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.87935 NH12 DepMap CRISPR Gene Dependency 1.0 2.64953 HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null ZKSCAN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33004 NGFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63267 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.989279 CFPAC1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.37444 Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7637 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09695 POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.39103 Outer acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.013 primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.892803 H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26649 Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4512-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.894219 HDLM2 CCLE Cell Line Gene CNV Profiles -1.0 -2.3562 Perturb_8148_KD_NKRF_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.35941 Intralaminar nuclei of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58099 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.863186 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.43187 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45753 Perturb_4314_KO_Hdac4_SRP219834 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.0585 r2 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78363 Parafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63075 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53755 Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMEL CCLE Cell Line Gene Expression Profiles 1.0 2.42278 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.971636 Perturb_7179_KO_TrEx_SRP163035 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.52176 Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54067 Fbxl10_OE_GSE34691_579_mouse_fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null USP38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78711 COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33407 Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.32955 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.60657 stomach_3b HPA Tissue Sample Gene Expression Profiles 1.0 2.91364 P4HB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09887 CCLFUPGI0005T DepMap CRISPR Gene Dependency 1.0 2.21 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_2051_KD_EIF4A3_SRP271455 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.53542 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00069 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33171 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null agnathia-otocephaly complex DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.194 HCC4006 CCLE Cell Line Gene Expression Profiles -1.0 -1.67974 EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9948_KD_HNRNPA2B1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.33349 Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06014 Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15448 H3K36me3_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3892_KO_Lonp1_SRP301760 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.48554 primary auditory cortex (core)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.942359 amygdaloid complex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1141 SKMEL2 CCLE Cell Line Gene Expression Profiles -1.0 -1.46844 CTCF_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16667 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.62083 POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LXF289 CCLE Cell Line Gene CNV Profiles -1.0 -1.52088 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC3348545-NIHMS263168-supplement-3.pdf-15-ZGPAT_ZGPAT Rummagene Transcription Factor Associations 2026 1.0 null ONDA9 DepMap CRISPR Gene Dependency 1.0 4.74681 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null dentate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.962336 496100382_PCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.23356 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.936893 MON DepMap CRISPR Gene Dependency 1.0 6.08517 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1523 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4873-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22262 ZNF669 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.435 PMC9580020-tx2c00131_si_004.xlsx-Fig_5B_data-TABLE_S3_CORE_GENE_TARGETS_HSF1_KOVACS_ET_AL_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H2444 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 liminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59376 nucleus of the stria terminalis, medial division, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31775 HCC89 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4734 HCC1428 CCLE Cell Line Gene CNV Profiles 1.0 1.5817 esophagus_5c HPA Tissue Sample Gene Expression Profiles -1.0 -1.07826 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51068 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.927143 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Sperm plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.588 ZNF644 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46021 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.892609 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06313 Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8099_KD_UBE2L3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.79932 amygdaloid complex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2791 H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXO1_KD_GDS2720_478_mouse_LSK GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.1942 primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5237 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02189 SOX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94505 Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.43343 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49231 subpallial septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19044 NSUN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60662 Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.72313 duodenum HPA Tissue Protein Expression Profiles 1.0 0.898233 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.97165 SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.38279 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal motor nucleus of the vagus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.056 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05266 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.64581 KYSE-520 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33027 PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08563 HS 852.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11165 CAL29 CCLE Cell Line Gene CNV Profiles 1.0 1.40935 TE8 CCLE Cell Line Gene CNV Profiles 1.0 1.47976 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893385 posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.927889 DMS 79 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.914484 Perturb_8173_KD_KHDRBS1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.97572 METTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75791 superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00334 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43236 Astrocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.555 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.98486 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.80993