association dataset threshold value standardized value PANC-08-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE168797_1_v_6_cannabidiol_human RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A6E2-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anteroventral part of alar thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07258 GSE174498,GSE174500_0_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null TCF4 ChEA Transcription Factor Targets 1.0 null intracellular organelle lumen GO Cellular Component Annotations 2025 1.0 null OUMS-23 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Hepatopancreas TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.907 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.81733 GTEX-QVUS-0008-SM-447AY GTEx Tissue Sample Gene Expression Profiles 1.0 0.968035 superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49639 GTEX-QEL4-2126-SM-447AE GTEx Tissue Sample Gene Expression Profiles 1.0 1.01067 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Central amygdalar nucleus, capsular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27458 Acute Myeloid Leukemia_LAML_TCGA-AB-2873-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1 ENCODE Transcription Factor Targets 1.0 null Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.2963 GTEX-XPVG-0626-SM-4B65B GTEx Tissue Sample Gene Expression Profiles 1.0 0.836989 COLO-679 COSMIC Cell Line Gene Mutation Profiles 1.0 null catalytic activity GO Molecular Function Annotations 2015 1.0 null KDM5B-21448134-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.4493 superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.12738 Nasal cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.15 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6825-01A-21R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-4666-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subpallial amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 GSE196540,GSE196542_4_v_3_dnmt3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null YH13 DepMap CRISPR Gene Dependency 1.0 2.94616 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41521 superficial stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43803 USH1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34581 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lipid metabolic process GO Biological Process Annotations 2015 1.0 null Posterolateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58024 MUC3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88505 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6774 abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.097321 NUCB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.90326 AK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40993 GTEX-PVOW-0011-R1A-SM-32PL6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.881985 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2329 CABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93637 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043608 GTEX-PWOO-0008-SM-48TDU GTEx Tissue Sample Gene Expression Profiles 1.0 1.16524 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945592 monocarboxylic acid biosynthetic process GO Biological Process Annotations 2025 1.0 null AOB, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51686 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100354_PCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.22586 GTEX-S33H-0326-SM-4AD6N GTEx Tissue Sample Gene Expression Profiles 1.0 0.833187 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRR15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24883 GTEX-RVPU-2326-SM-2TF6R GTEx Tissue Sample Gene Expression Profiles 1.0 1.0439 Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2227 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE182185_0_v_1_pstk_human RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7209-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tetracosanoyl-CoA HMDB Metabolites of Enzymes 1.0 null Butyric acid MW Enzyme Metabolite Associations 1.0 null MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58146 SUM149PT DepMap CRISPR Gene Dependency 1.0 7.30802 SLC16A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57756 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 3 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08734 GATC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57094 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2058 CEBPB ENCODE Transcription Factor Targets 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null layer 2 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.6091 Valeric acid HMDB Metabolites of Enzymes 1.0 null NCAPH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33995 CMTM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67707 fatty acid metabolic process GO Biological Process Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7060-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUGC2 CCLE Cell Line Gene CNV Profiles 1.0 1.85986 GSE164494_0_v_2_rab22a_mouse RummaGEO Gene Perturbation Signatures -1.0 null SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25634 Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasmic chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.282558 PPP1R14A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04314 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041628 HO-1-N-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null AGPAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80033 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2836 binding GO Molecular Function Annotations 2015 1.0 null ISG20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61431 ZDHHC18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47365 dorsal lateral geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46043 paraseptal subpallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00749 purine ribonucleotide metabolic process GO Biological Process Annotations 2023 1.0 null External plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.703 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6671 MPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72316 Magnesium HMDB Metabolites of Enzymes 1.0 null HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0433 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.209 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null (2E)-Tetradecenoyl-CoA HMDB Metabolites of Enzymes 1.0 null Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33929 lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19218 periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 NUDHL1 CCLE Cell Line Gene CNV Profiles 1.0 1.40174 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM43A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37774 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.55217 intermediate stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01979 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4N-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFP36L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55757 MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03743 SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58146 GTEX-Q734-0626-SM-2I3EF GTEx Tissue Sample Gene Expression Profiles 1.0 0.863487 UQCC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67624 ribonucleoside bisphosphate metabolic process GO Biological Process Annotations 2023 1.0 null Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18291 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4126 ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCC5 DepMap CRISPR Gene Dependency 1.0 5.01987 GSE248858_6_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216274,GSE216292_4_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58146 IGR39 DepMap CRISPR Gene Dependency 1.0 2.25665 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFAND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57956 Acute Myeloid Leukemia_LAML_TCGA-AB-2940-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04499 ZNF625 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76967 DMS-53 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IGROV1 DepMap CRISPR Gene Dependency 1.0 2.87612 ventromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58195 r9 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34593 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31843 GSE145639_1_v_6_adar_human RummaGEO Gene Perturbation Signatures -1.0 null neoplasm of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.260974 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAB6D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27261 periventricular stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 human immunodeficiency virus infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.760639 GSE229671,GSE229673_3_v_1_yrdc_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SAMD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48154 SW48 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100347_PCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.773 Lung adenocarcinoma_LUAD_TCGA-78-7220-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Slit-Robo signaling complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.534 PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1 Rummagene Transcription Factor Associations 2026 1.0 null SK-ES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null CEBPB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58024 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 Conjugation of salicylate with glycine Reactome Pathways 2014 1.0 null TMEM63B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6275 GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56142 Lung adenocarcinoma_LUAD_TCGA-75-7027-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Reactome Pathways 2014 1.0 null Apocrine carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.321 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9105 CAKI1 DepMap CRISPR Gene Dependency 1.0 5.46781 GSE216273,GSE216292_14_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null TMEM141 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04239 ERF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42486 IM-95 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.7202 Thyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.96738 trans-2-Hexenoyl-CoA HMDB Metabolites of Enzymes 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039759 PKN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.35072 LMX1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46887 FOXR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82707 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8778 GSE81193_3_v_5_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null ATP6V0E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02748 nucleotide binding GO Molecular Function Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5162-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7219-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DJM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU1F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74068 r11 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22001 viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.554403 GTEX-XGQ4-0008-SM-4AT3Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.23888 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.024 abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.123928 MFE280 DepMap CRISPR Gene Dependency 1.0 3.93503 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 2.03493 PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.18903 GSE165636_0_v_4_tofacitinib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_1_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46043 JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null pancreas GTEx Tissue Gene Expression Profiles -1.0 -1.48278 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882477 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletal muscle HPA Tissue Protein Expression Profiles -1.0 -0.82284 P2RX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01295 mantle zone of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11383 Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZKSCAN1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null Cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 TE-8 COSMIC Cell Line Gene Mutation Profiles 1.0 null Ost-alpha/Ost-beta complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.585 prostate HPA Tissue Protein Expression Profiles 1.0 1.38393 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041249 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8929 Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UPK5-1626-SM-4JBHI GTEx Tissue Sample Gene Expression Profiles 1.0 1.07354 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANKRD16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85327 acquired immunodeficiency syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.863456 ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26046 Perturb_2095_KD_EIF4A3_SRP226707 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.52739 ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8632 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846228 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null DENND4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07081 sulfur compound metabolic process GO Biological Process Annotations 2015 1.0 null NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3424 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.69642 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9961 Brain Lower Grade Glioma_LGG_TCGA-DU-6401-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A_CA_04_2009_7dayMOI-10^3_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.40579 NCIH2171 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 E2F4 ENCODE Transcription Factor Targets 1.0 null ATG2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36048 GSE200673,GSE200691_1_v_3_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null lipid biosynthetic process GO Biological Process Annotations 2023 1.0 null TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null LS1034 CCLE Cell Line Gene CNV Profiles 1.0 2.10432 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null H4K91ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1648 Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ethmoid bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.963 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AKR1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08115 Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SORD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86667 Heptanoic acid HMDB Metabolites of Enzymes 1.0 null RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4632 ZNF860 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55332 TSPYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39278 GTEX-QEG4-0008-SM-48TYZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.03426 TT1TKB DepMap CRISPR Gene Dependency 1.0 2.62435 purine ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.028135 C32 DepMap CRISPR Gene Dependency 1.0 2.94883 SHP-77 COSMIC Cell Line Gene Mutation Profiles 1.0 null spleen GTEx Tissue Gene Expression Profiles 1.0 1.67633 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.66246 organ system cancer GWASdb SNP-Disease Associations 1.0 0.038432 UBC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31806 superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66414 ZNF528 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60452 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4827 GATA1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.965653 AOB, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43803 S1PR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66414 r6 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50442 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JZ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01682 Kidney Chromophobe_KICH_TCGA-KN-8424-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P12ICHIKAWA CCLE Cell Line Gene CNV Profiles -1.0 -1.42063 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 2.06459 superficial stratum of CA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37415 Adenosine monophosphate HMDB Metabolites of Enzymes 1.0 null CFAP119 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55415 GSE77108_8_v_1_saha_human RummaGEO Drug Perturbation Signatures -1.0 null GSE135312_1_v_2_bmpr2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE145639_1_v_2_adar_human RummaGEO Gene Perturbation Signatures -1.0 null Refractive error GWAS Catalog SNP-Phenotype Associations 2025 1.0 6.15229 PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9729 TMEM201 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67941 TMSB4X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83614 GSE174498,GSE174500_5_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-UJHI-0126-SM-4IHLP GTEx Tissue Sample Gene Expression Profiles 1.0 1.4835 SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5466 lipid biosynthetic process GO Biological Process Annotations 2025 1.0 null NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6575 H1-6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17819 H3K27me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14752_KO_H3F3A_SRP252213 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.16629 RL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.945491 PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4312 intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45781 Overnutrition DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 1.09095 RAB17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93004 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EF-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PEO4 DepMap CRISPR Gene Dependency 1.0 4.36924 GSE127790_9_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null FOXD4L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.30813 Endopiriform nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27458 NCIH2052 DepMap CRISPR Gene Dependency 1.0 2.13796 Field CA2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10251 GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.13948 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null OLFML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4405 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null CL-40 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01179 ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7031 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28458 STAT3 ChEA Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7128-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ML-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF529 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3817 ethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27458 LPCAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81917 RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.036 Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Decanoyl-CoA (n-C10:0CoA) HMDB Metabolites of Enzymes 1.0 null NCIH929 CCLE Cell Line Gene CNV Profiles -1.0 -1.70588 GTEX-OHPN-0226-SM-48TBV GTEx Tissue Sample Gene Expression Profiles 1.0 0.984851 Dorsal part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51595 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.70326 ZNF195 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61667 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1677 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943527 GTEX-T5JC-2126-SM-32PMO GTEx Tissue Sample Gene Expression Profiles 1.0 1.04441 Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2865-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE135030_3_v_0_fludarabine_human RummaGEO Drug Perturbation Signatures -1.0 null Supramammillary nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09195 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M5-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100561_PCx_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.72239 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53708 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854652 GSE248858_6_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null ZNF852 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84741 Acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.046 HUH1 CCLE Cell Line Gene CNV Profiles -1.0 -1.75948 ARMCX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28232 GTEX-OXRP-0226-SM-3NB14 GTEx Tissue Sample Gene Expression Profiles 1.0 0.918102 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD4-21741376-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4774 p3 part of the ZL core Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 mitochondrial nucleoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.283295 AMP-dependent synthetase/ligase InterPro Predicted Protein Domain Annotations 1.0 null NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.41534 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.77483 Prostate adenocarcinoma_PRAD_TCGA-HC-7744-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF418 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07247 ligase activity GO Molecular Function Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Abdominal obesity-metabolic syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.537 GSE251992_1_v_0_saracatinib_human RummaGEO Drug Perturbation Signatures -1.0 null SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1429 Perturb_9107_KD_G6PD_SRP287480 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.33672 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JO-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH196 CCLE Cell Line Gene CNV Profiles -1.0 -2.43816 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ZNF518A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01442 CAL72 DepMap CRISPR Gene Dependency 1.0 2.91467 IA-LM COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 GSE219195_0_v_5_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE172189_0_v_1_venetoclax_human RummaGEO Drug Perturbation Signatures 1.0 null Refsum disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.14 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927146 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041934 SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.7474 basolateral amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10251 CD164L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04168 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 2.27871 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.1788 Octanoyl-CoA HMDB Metabolites of Enzymes 1.0 null DHRS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02173 KP4 CCLE Cell Line Gene CNV Profiles 1.0 1.77658 KLF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8213 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.37745 Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA3, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66021 ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 120.971 GTEX-Q2AG-2926-SM-2HMJ3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.955488 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 44.7044 Dopaminergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.887 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26A-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pyrophosphate HMDB Metabolites of Enzymes 1.0 null Signal recognition particle receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.735 Glomerular layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.833 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null Butanoyl-CoA MW Enzyme Metabolite Associations 1.0 null CRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12061 Conjugation of carboxylic acids Reactome Pathways 2014 1.0 null SMAD3-21741376-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE229973_3_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.9432 HIP1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80264 eGFP-FOS_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42938 ZNF319 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17244 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.3101 GSE201520_8_v_3_inhba_mouse RummaGEO Gene Perturbation Signatures -1.0 null DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5032 GSE227698_2_v_4_g0s2_human RummaGEO Gene Perturbation Signatures -1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null SUSA DepMap CRISPR Gene Dependency 1.0 2.28288 GATA2 ENCODE Transcription Factor Targets 1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27661 KNS-81-FD COSMIC Cell Line Gene Mutation Profiles 1.0 null FAM210B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97157 GSE87617_1_v_0_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE65617_5_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null FTSJ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06946 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23747 NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03743 intermediate stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50633 GSE139540_0_v_2_menadione_human RummaGEO Drug Perturbation Signatures -1.0 null intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MAFA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.928 PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO800 DepMap CRISPR Gene Dependency 1.0 2.80565 GSE115363_2_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null Cerebral arterial disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 THP1 CCLE Cell Line Gene CNV Profiles -1.0 -2.06979 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8812 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR Rummagene Transcription Factor Associations 2026 1.0 null LMO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06828 Perturb_12290_KO_ERO1_ERP137480 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.56534 DUSP23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41647 disease GWASdb SNP-Disease Associations 1.0 0.023792 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 2.11217 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.69483 CCNT2 ENCODE Transcription Factor Targets 1.0 null mitochondrial part GO Cellular Component Annotations 2015 1.0 null mantle zone of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28766 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55427 201T COSMIC Cell Line Gene Mutation Profiles 1.0 null 2-Methylbutyryl-CoA HMDB Metabolites of Enzymes 1.0 null XPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43333 PK59 CCLE Cell Line Gene CNV Profiles -1.0 -1.3853 HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBC1 CCLE Cell Line Gene CNV Profiles 1.0 1.34148 membrane-enclosed lumen GO Cellular Component Annotations 2015 1.0 null KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36683 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.978272 UBE2D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72376 Electron transfer flavoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.69 GSE216273,GSE216292_14_v_8_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null CAL-33 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.77335 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.062691 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.82329 GTEX-P44H-0326-SM-2XCES GTEx Tissue Sample Gene Expression Profiles 1.0 1.07852 Glutaconyl-CoA HMDB Metabolites of Enzymes 1.0 null acyl-CoA metabolic process GO Biological Process Annotations 2023 1.0 null ZNF749 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50837 lung cancer GWASdb SNP-Disease Associations 1.0 0.545096 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ISYNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53232 AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59098 Perturb_12516_KD_TRA2B_SRP221583 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.8219 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.71218 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00342 Sarcoma_SARC_TCGA-FX-A3NJ-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.78489 GATA1 ChEA Transcription Factor Targets 1.0 null ERCC6L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68397 GTEX-S7SF-0008-SM-3NM8T GTEx Tissue Sample Gene Expression Profiles 1.0 0.996712 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-BHLHE22_BHLHE22 Rummagene Transcription Factor Associations 2026 1.0 null Cerebrovascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 SMAD3-21741376-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JC-0008-SM-4DM6A GTEx Tissue Sample Gene Expression Profiles 1.0 0.843449 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5523 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877672 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.64921 thioester metabolic process GO Biological Process Annotations 2015 1.0 null RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05138 acid-thiol ligase activity GO Molecular Function Annotations 2015 1.0 null ATF3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null acquired immunodeficiency syndrome; disease progression GAD Gene-Disease Associations 1.0 null GSE130401_1_v_0_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.944452 VN1R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73595 GSE186620_0_v_1_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE120216_3_v_0_cbfb_human RummaGEO Gene Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE196671_5_v_1_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZBED6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.72652 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.889536 NCIH1648 DepMap CRISPR Gene Dependency 1.0 2.19857 intermediate stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41137 GATA1 ENCODE Transcription Factor Targets 1.0 null TRIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05181 Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Obesity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.086 GSE174498,GSE174500_2_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null ACBD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13581 YWHAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78938 USP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94783 OV7 CCLE Cell Line Gene CNV Profiles -1.0 -1.3468 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B6-01A-21R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCFC1 ENCODE Transcription Factor Targets 1.0 null Pristanoyl-CoA HMDB Metabolites of Enzymes 1.0 null HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0129 GSE216273,GSE216292_14_v_6_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Central amygdalar nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE223008_11_v_12_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877527 MERO82 DepMap CRISPR Gene Dependency 1.0 4.73571 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BZW1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67921 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 68.7714 UM-UC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.979803 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21017 Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mitochondrial matrix GO Cellular Component Annotations 2025 1.0 null BCAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62999 mantle zone of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49028 TMEM198 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99468 SF295 DepMap CRISPR Gene Dependency 1.0 5.20337 CLCN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26183 IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5706 SMAD3 ChEA Transcription Factor Targets 1.0 null BLCAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8817 LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null YBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23027 TP53BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36172 FU97 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE216326_2_v_0_sulodexide_mouse RummaGEO Drug Perturbation Signatures 1.0 null Peroxisomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.832 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.427765 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4265 Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Basomedial amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51595 GALK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31622 mantle zone of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44356 monocarboxylic acid biosynthetic process GO Biological Process Annotations 2023 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.54013 GSE174498,GSE174500_3_v_4_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8506-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0672 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Field CA1, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17746 Uterus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TGDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04026 NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16705 rapid GeneRIF Biological Term Annotations 1.0 null GSE218580_1_v_0_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63045 Ammon's horn Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19848 Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1562 GSE164494_0_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.84386 UMUC9 DepMap CRISPR Gene Dependency 1.0 2.13192 Cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Intracranial arterial disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 GSE90821_3_v_1_esrp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ICAM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30406 fatty-acyl-CoA synthase activity GO Molecular Function Annotations 2023 1.0 null PATL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69662 S1PR5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35939 GTEX-S4Z8-0226-SM-4AD5K GTEx Tissue Sample Gene Expression Profiles 1.0 1.40681 H3K27me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49B-01A-31R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07258 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE127790_10_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null placenta HPA Tissue Protein Expression Profiles -1.0 -0.82284 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null HOXA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59491 LS123 CCLE Cell Line Gene CNV Profiles 1.0 1.46579 KRCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63851 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0566 layer 6 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08734 GSE218580_1_v_2_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null ATP MW Enzyme Metabolite Associations 1.0 null TBC1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51232 HOXA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57349 periventricular stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0298 Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11962_KO_Tr1_SRP355815 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.0885 PANX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52951 SK-MM-2 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.15503 VPS33A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31214 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.5932 Perturb_12291_KO_ERO1_ERP137480 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.205 Hoxd13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.7392 nucleoside phosphate binding GO Molecular Function Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.0095 r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03385 GSE76425_0_v_10_lenalidomide_human RummaGEO Drug Perturbation Signatures 1.0 null Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Reactome Pathways 2014 1.0 null PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877527 GSE120612_7_v_1_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A427 DepMap CRISPR Gene Dependency 1.0 2.0822 GSS DepMap CRISPR Gene Dependency 1.0 2.21287 GTEX-UTHO-1826-SM-3GAFE GTEx Tissue Sample Gene Expression Profiles 1.0 0.946706 MCC142 DepMap CRISPR Gene Dependency 1.0 6.15397 DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2611 MELK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56256 GTEX-P4QS-0926-SM-48TBS GTEx Tissue Sample Gene Expression Profiles 1.0 1.12415 Brain Lower Grade Glioma_LGG_TCGA-FG-6689-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERMES complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.056 LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5408 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.78958 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J5-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09076 GSE239844_7_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null XIAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23656 ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6644 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5116 Perturb_4412_KO_Eed_SRP172483 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.03438 GSE218580_1_v_3_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null MSH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.20958 WDR74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51042 CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1332 GSE127790_4_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null VIM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20435 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_10234_KO_FAM120A_SRP384156 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.38718 GTEX-U3ZH-0008-SM-4DXT2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.902045 r9 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16944 r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39267 LMAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8547 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21017 SNU620 DepMap CRISPR Gene Dependency 1.0 3.74457 HEK-293A cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.601 MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38134 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RF-48 COSMIC Cell Line Gene Mutation Profiles 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846228 MEWO CCLE Cell Line Gene CNV Profiles -1.0 -1.85659 Nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2009 GTEX-U3ZH-0526-SM-3DB75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08638 SKOV3 CCLE Cell Line Gene CNV Profiles -1.0 -1.53341 GTEX-SN8G-0008-SM-4DM4X GTEx Tissue Sample Gene Expression Profiles 1.0 1.01714 BAZ1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55682 496100558_PCx_probable Alzheimer's disease_TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.5121 CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41018 GTEX-T5JW-0008-SM-4DM5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.954072 accumbens nucleus, shell domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86673 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CD-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.53753 cytoplasmic part GO Cellular Component Annotations 2015 1.0 null ETV7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3397 UBE2G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88604 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADAMTS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64832 intermediate stratum of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12404 Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RECQL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52703 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.0472 monocarboxylic acid metabolic process GO Biological Process Annotations 2015 1.0 null tonsil HPA Tissue Protein Expression Profiles -1.0 -0.82284 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR Rummagene Transcription Factor Associations 2026 1.0 null aids GeneRIF Biological Term Annotations 1.0 null GATA1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE200673,GSE200691_2_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZBTB7A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9393 GSE193751_1_v_3_oridonin_human RummaGEO Drug Perturbation Signatures -1.0 null Claustrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46043 Sarcoma_SARC_TCGA-DX-A1L3-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH23 CCLE Cell Line Gene CNV Profiles 1.0 1.51382 Rectum adenocarcinoma_READ_TCGA-G5-6235-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0827 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CV-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.3023 ZNF384 ENCODE Transcription Factor Targets 1.0 null GSE142210_3_v_7_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null TAL1 ENCODE Transcription Factor Targets 1.0 null PGGHG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36625 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 RNF38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90731 CYB5R3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38376 HA1E DepMap CRISPR Gene Dependency 1.0 3.01261 D-245MG COSMIC Cell Line Gene Mutation Profiles 1.0 null LEPROT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51776 shell of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 GTEX-QDVJ-1826-SM-2S1P3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02455 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intrinsic component of cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.673 EAPP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61087 layer 4 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.11017 BE2-M17 COSMIC Cell Line Gene Mutation Profiles 1.0 null Acetyl-CoA HMDB Metabolites of Enzymes 1.0 null GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles 1.0 0.827991 PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF Rummagene Transcription Factor Associations 2026 1.0 null FDXACB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14479 atp binding GO Molecular Function Annotations 2015 1.0 null eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IA-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-0008-SM-447AU GTEx Tissue Sample Gene Expression Profiles 1.0 0.85029 fatty acid metabolic process GO Biological Process Annotations 2025 1.0 null YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33395 Lung adenocarcinoma_LUAD_TCGA-86-A456-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TI-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3681 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 67.4722 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PGAP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34542 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.694 COPS7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49322 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7372-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0189 MAFF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60559 FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.0926 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TT-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX3-22085726-MUSCLE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null respiratory system cancer GWASdb SNP-Disease Associations 1.0 0.24149 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ventral medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33929 RBFOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79902 Sarcoma_SARC_TCGA-PC-A5DO-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3326-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null TMEM14B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77881 MARK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4655 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFO21 CCLE Cell Line Gene CNV Profiles -1.0 -2.40098 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.53443 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.256 intermediate part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44634 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 2.15089 Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ion binding GO Molecular Function Annotations 2015 1.0 null ZDHHC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31269 GTEX-U8T8-0008-SM-4DXSP GTEx Tissue Sample Gene Expression Profiles 1.0 1.00632 Central medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01979 KLM1 CCLE Cell Line Gene CNV Profiles 1.0 1.49773 D-423MG COSMIC Cell Line Gene Mutation Profiles 1.0 null SCLY ChEA Transcription Factor Targets 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08779 HT1197 DepMap CRISPR Gene Dependency 1.0 2.34876 GTEX-S33H-1126-SM-2XCB6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.933597 NCIH28 DepMap CRISPR Gene Dependency 1.0 2.45649 Periplasmic side of cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.673 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07164 KMT5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78098 r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66467 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 5 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22198 NCIH650 DepMap CRISPR Gene Dependency 1.0 2.00884 MEA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81546 purine ribonucleoside binding GO Molecular Function Annotations 2015 1.0 null FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9079 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GNE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67782 BHLHE40 ENCODE Transcription Factor Targets 1.0 null C17orf107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27304 C7orf50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54262 SPI1 ChEA Transcription Factor Targets 1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901778 GSE210101,GSE210114_7_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.68221 HDAC1 ENCODE Transcription Factor Targets 1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15843 SKMEL31 CCLE Cell Line Gene CNV Profiles 1.0 1.71604 CCDC71 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76428 HCC33 CCLE Cell Line Gene CNV Profiles 1.0 2.02437 Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.5404 terete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75939 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46307 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 2.41262 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.86833 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042103 SCML1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50818 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 L1CAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12821 GSE205163,GSE205164_3_v_7_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null Eyestalk TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.267 parathyroid gland HPA Tissue Protein Expression Profiles 1.0 1.38393 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.3331 AMP-binding, conserved site InterPro Predicted Protein Domain Annotations 1.0 null r10 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07238 Acrylyl-CoA HMDB Metabolites of Enzymes 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles 1.0 1.11432 SCL-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PL4 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IGHMBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92427 Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92246 retrosplenial cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02911 SMAD4 ChEA Transcription Factor Targets 1.0 null GSE133329_0_v_3_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE173810_4_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Acquired Immunodeficiency Syndrome HuGE Navigator Gene-Phenotype Associations 1.0 null SLC25A28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36692 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null organic substance metabolic process GO Biological Process Annotations 2015 1.0 null ZKSCAN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7111 SATB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18576 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Basolateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30554 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 2.32287 CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.40021 GSE236003_1_v_3_ubr5_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.58386 spleen HPA Tissue Protein Expression Profiles -1.0 -0.82284 ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.4299 intracellular organelle lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.072113 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08035 JTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84568 DMS153 CCLE Cell Line Gene CNV Profiles -1.0 -1.45382 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Glycolate oxidase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.793 H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE166315_5_v_0_docetaxel_mouse RummaGEO Drug Perturbation Signatures 1.0 null NCIH146 CCLE Cell Line Gene CNV Profiles 1.0 1.59425 Basomedial amygdalar nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1562 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CK-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR Rummagene Transcription Factor Associations 2026 1.0 null Rto TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.129 TST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67769 PGM2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47571 GTEX-O5YT-0526-SM-32PK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18565 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04893 S100A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30582 Agranular insular area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05734 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04499 glycerol-3-phosphate dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.064 ChaGo-K-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.712 Bam protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.673 FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Aspirin ADME Reactome Pathways 2024 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.7581 Brain disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 UBTF ENCODE Transcription Factor Targets 1.0 null GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17088 r86 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.395 YD38 DepMap CRISPR Gene Dependency 1.0 4.95257 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-0526-SM-2I3DX GTEx Tissue Sample Gene Expression Profiles 1.0 0.83056 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24731 MAFF ENCODE Transcription Factor Targets 1.0 null RPL12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90445 Metabolism Reactome Pathways 2014 1.0 null TC71 CCLE Cell Line Gene CNV Profiles -1.0 -1.45696 transferase activity GO Molecular Function Annotations 2015 1.0 null RCHACV DepMap CRISPR Gene Dependency 1.0 3.47055 Perturb_13933_KO_TRPM2_SRP360994 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.39437 GSE158815_1_v_3_trib1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ARHGEF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38866 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.59243 SC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1703 CCLE Cell Line Gene CNV Profiles 1.0 1.68018 RHOXF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31705 TMEM80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26956 layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.57509 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.2329 Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Iminoglycinuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.121 Field CA2, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00749 GSE234289_4_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4422 IKZF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22616 LC4-1 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.14414 FOXA2 ENCODE Transcription Factor Targets 1.0 null METTL25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36561 GTEX-P4QS-0526-SM-2I3ET GTEx Tissue Sample Gene Expression Profiles 1.0 1.03205 GTEX-UPK5-1826-SM-3GAEB GTEx Tissue Sample Gene Expression Profiles 1.0 1.11738 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34507 U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.944452 LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Field CA3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27458 CEBPD_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCDC96 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.26992 GSE218580_1_v_5_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null p2 part of the zona limitans core population Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07258 NTHL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19508 GTEX-W5X1-2626-SM-4LMI8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.847576 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 2.0325 ZNF554 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89233 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE151612_0_v_2_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null POLL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.25083 accumbens nucleus, core domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 IL27RA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54101 JHU022 DepMap CRISPR Gene Dependency 1.0 4.06572 SEMA6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46393 PCDHB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9368 RND2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41517 cancer GWASdb SNP-Disease Associations 1.0 0.036846 purine nucleoside bisphosphate metabolic process GO Biological Process Annotations 2023 1.0 null Prostate gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KDM5B-21448134-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-X8HC-0226-SM-4E3K1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0086 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Leber congenital amaurosis 12 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.316 NANOG ChEA Transcription Factor Targets 1.0 null GATA1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1183 GTEX-OOBK-0226-SM-2YUMF GTEx Tissue Sample Gene Expression Profiles 1.0 1.32693 MAF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2366 FOXA2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mitochondrial matrix GO Cellular Component Annotations 2023 1.0 null GSE216273,GSE216292_14_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null Ventral posteromedial nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08734 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2791 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7654-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FUS-26573619-CHIP-SEQ-HEK293-HUMAN ChEA Transcription Factor Targets 2022 1.0 null C-acyltransferase activity GO Molecular Function Annotations 2025 1.0 null GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.80352 GSE239844_7_v_2_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null EMTOKA DepMap CRISPR Gene Dependency 1.0 4.30652 Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51801 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32549 HEG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90283 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE176008_0_v_3_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null r2 part of superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12328 CORL88 CCLE Cell Line Gene CNV Profiles 1.0 1.39513 GSE216273,GSE216292_14_v_2_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null HDLM2 CCLE Cell Line Gene CNV Profiles 1.0 1.75393 Perturb_2122_KD_XRN2_SRP276651 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.46494 Perturb_6540_KO_XIST_SRP301287 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.86263 GTEX-Q2AI-0008-SM-48U2H GTEx Tissue Sample Gene Expression Profiles 1.0 1.10346 Cribriform plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.979 MDAMB436 CCLE Cell Line Gene CNV Profiles 1.0 1.5234 Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acyl-CoA metabolic process GO Biological Process Annotations 2025 1.0 null intermediate stratum of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41312 GTEX-X62O-0008-SM-46MU5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44788 thioester metabolic process GO Biological Process Annotations 2025 1.0 null GTEX-P78B-0226-SM-3NB1Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.943295 ribonucleoside binding GO Molecular Function Annotations 2015 1.0 null Conjugation of carboxylic acids Reactome Pathways 2024 1.0 null GSE200673,GSE200691_1_v_0_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null striatal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07258 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 97.3969 CUX1 ENCODE Transcription Factor Targets 1.0 null AIRE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82072 GTEX-TMZS-0226-SM-3DB9N GTEx Tissue Sample Gene Expression Profiles 1.0 0.840788 GTEX-WFG8-0926-SM-3GIKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.1849 NDUFS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37688 H3K27me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null A3-KAW COSMIC Cell Line Gene Mutation Profiles 1.0 null JcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23786 Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.78016 GSE76425_0_v_5_lenalidomide_human RummaGEO Drug Perturbation Signatures 1.0 null Adenosine triphosphate HMDB Metabolites of Enzymes 1.0 null Caproic acid HMDB Metabolites of Enzymes 1.0 null FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3277 NCI-H2373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43994 GSE202359_1_v_0_rbpms_mouse RummaGEO Gene Perturbation Signatures 1.0 null r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.12654 Nutrition disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.08 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.8578 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.8729 496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.64051 CARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77059 MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1652 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7501-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51595 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.4277 periventricular stratum of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 GSE162739_7_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null UBALD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87046 transferase activity, transferring acyl groups GO Molecular Function Annotations 2015 1.0 null Phase II conjugation Reactome Pathways 2014 1.0 null MEIS1-26253404-OPTIC-CUPS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.8855 Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33278 SERINC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92682 MM160113 DepMap CRISPR Gene Dependency 1.0 2.16152 Brain Lower Grade Glioma_LGG_TCGA-FG-A87N-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RARA-24833708-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.1677 496100429_TCx_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.37112 intermediate stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34634 MAVS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43109 fatty-acyl-coa synthase activity GO Molecular Function Annotations 2015 1.0 null intercalated amygdaloid nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02623 GSE135030_3_v_9_fludarabine_human RummaGEO Drug Perturbation Signatures -1.0 null JUN_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1202 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null Undecanoic acid HMDB Metabolites of Enzymes 1.0 null GSE183271_1_v_0_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8567 lateral part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21923 496100468_PCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20047 MSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74546 GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles 1.0 0.907802 Plume TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.622 transferase activity, transferring acyl groups other than amino-acyl groups GO Molecular Function Annotations 2015 1.0 null (2E)-Dodecenoyl-CoA HMDB Metabolites of Enzymes 1.0 null NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.08 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lambdoid septal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24731 C21orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44709 GTEX-PVOW-0008-SM-48TE8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.928521 FRS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5715 H3K9me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null SAP30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91125 CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null adipose tissue GTEx Tissue Gene Expression Profiles 1.0 0.826098 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.93436 GSE205163,GSE205164_3_v_6_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-POYW-1226-SM-2XCEP GTEx Tissue Sample Gene Expression Profiles 1.0 0.872224 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KC-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RRP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21255 STAT5A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5275-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1341 FBXO28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2558 Familial chylomicronemia syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.281 Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.9817 ventral posterior parvicellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27458 SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846228 PMC4273559__F3 PFOCR Pathway Figure Associations 2023 1.0 null PTGR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03855 ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.2341 BMF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90655 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927146 DEF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09837 Lung adenocarcinoma_LUAD_TCGA-MP-A4TF-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-J2-8192-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877085 hippocampus (cortex Ammonis) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37415 GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles 1.0 0.833207 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZR751 CCLE Cell Line Gene CNV Profiles 1.0 1.71936 (2E)-Hexadecenoyl-CoA HMDB Metabolites of Enzymes 1.0 null GSE200673,GSE200691_1_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null 2-Methylhexanoyl-CoA HMDB Metabolites of Enzymes 1.0 null PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.56622 GATA1_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-0526-SM-4DXTK GTEx Tissue Sample Gene Expression Profiles 1.0 0.93454 CHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4215 DPH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59607 superficial stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66148 ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null Coenzyme A HMDB Metabolites of Enzymes 1.0 null superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6261 HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CALML4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66297 Anchored component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.515 AMDHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54478 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63025 Defective UGT1A4 causes hyperbilirubinemia Reactome Pathways 2014 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45688 LSM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80479 mantle zone of CA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37415 butyrate-coa ligase activity GO Molecular Function Annotations 2015 1.0 null episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49733 thalamic (p2) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 organelle LOCATE Predicted Protein Localization Annotations 1.0 null IFT122 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81043 RFX5 ENCODE Transcription Factor Targets 1.0 null Central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-UTHO-0011-R4A-SM-3GIJP GTEx Tissue Sample Gene Expression Profiles 1.0 0.863399 SOX4 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_12515_KD_TRA2B_SRP221583 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.18747 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU739 DepMap CRISPR Gene Dependency 1.0 2.65507 Mitochondrial matrix COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 GSE182921_0_v_1_slit2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE174498,GSE174500_2_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null KMS21BM CCLE Cell Line Gene CNV Profiles -1.0 -1.93061 Central amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13717 GSE159678_6_v_3_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null Field CA3, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1562 CHK1_KD_GSE54267_671_human_U2OS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF620 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9974 GSE171826_1_v_3_rosiglitazone_human RummaGEO Drug Perturbation Signatures -1.0 null YIPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6571 GTEX-WY7C-0426-SM-3NB3C GTEx Tissue Sample Gene Expression Profiles 1.0 0.921151 Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.83019 BTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31316 Neuronal cell body membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.314 Lung adenocarcinoma_LUAD_TCGA-MP-A4TK-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 GSE135030_11_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null layer 6 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46043 ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.3492 Prostate adenocarcinoma_PRAD_TCGA-KK-A7B4-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216273,GSE216292_0_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null FEM1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23974 CAMA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.47043 Olfactory ensheathing cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.961 NR2F2 ENCODE Transcription Factor Targets 1.0 null Nasal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.445 FXYD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27057 HEP_3B2_1-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100665_PCx_probable Alzheimer's disease_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08663 LMCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19843 Rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41312 Perturb_4413_KO_Eed_SRP172483 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE138818_1_v_3_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null Fruit juice TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.836 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.875 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null CSNK1A1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80478 GSE152441,GSE152442_7_v_5_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null SMAD4-21741376-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 3Z-dodecenoyl-CoA HMDB Metabolites of Enzymes 1.0 null Primary somatosensory area, barrel field, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58195 ARID3A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VCAP COSMIC Cell Line Gene Mutation Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VI-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE213588_8_v_6_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.86066 LACTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99515 anion binding GO Molecular Function Annotations 2015 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5441-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCL-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63025 IFNGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74611 CREB1 ENCODE Transcription Factor Targets 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null Perturb_14179_KD_TP53_SRP200529 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.4265 Cell envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.028 RAB3IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03779 CTNNAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45041 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 ALS2CL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71627 periventricular stratum of JcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23786 small molecule binding GO Molecular Function Annotations 2015 1.0 null PHIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27313 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null NOS1 DepMap CRISPR Gene Dependency 1.0 9.65621 metal ion binding GO Molecular Function Annotations 2015 1.0 null GSE115363_2_v_0_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null cumulus-oocyte complex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.915 DB COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XK95-0008-SM-4AT5G GTEx Tissue Sample Gene Expression Profiles 1.0 1.16443 JHH2 CCLE Cell Line Gene CNV Profiles -1.0 -1.32309 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18801 H3K27me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22119 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.0705 carbohydrate derivative binding GO Molecular Function Annotations 2015 1.0 null GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.76523 GTEX-TML8-0008-SM-4DXUI GTEx Tissue Sample Gene Expression Profiles 1.0 0.984996 NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 2.46303 r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41311 prethalamic (p3) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00749 KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.59505 lymph node HPA Tissue Protein Expression Profiles -1.0 -0.82284 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.4614 Perturb_9088_KD_SUPT16H_SRP106869 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.94506 GTEX-T5JC-0526-SM-32PM7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.874576 CUX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68696 GSE65617_5_v_1_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -1.39513 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.92776 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7853 intermediate part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28808 LSR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39569 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46601 Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00987 DMS53 CCLE Cell Line Gene CNV Profiles 1.0 1.52628 Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94591 ARL2BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67186 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.0208 Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877672 TBL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43888 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QCQG-1826-SM-2S1P2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.825676 SNU16 CCLE Cell Line Gene CNV Profiles -1.0 -1.5808 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5636 Neck TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Brain Lower Grade Glioma_LGG_TCGA-DU-5852-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 0.943227 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I1-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13948_KD_CDK4/CDK6_SRP258989 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.81506 RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7021 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2484 CCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09899 ventral endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17746 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.061077 neoplasm of the lung GWASdb SNP-Phenotype Associations 1.0 0.464697 Basomedial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 GTEX-XQ8I-1726-SM-4BOQB GTEx Tissue Sample Gene Expression Profiles 1.0 0.974256 ATF3 ENCODE Transcription Factor Targets 1.0 null SOX11-22085726-ESNS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MEF2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3512 GSE168797_2_v_3_cannabidiol_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 0.963685 PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1343 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98382 neoplasm GWASdb SNP-Phenotype Associations 1.0 0.042874 KDM5A ENCODE Transcription Factor Targets 1.0 null SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39735 PSME3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97219 Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ligase activity, forming carbon-sulfur bonds GO Molecular Function Annotations 2015 1.0 null NCI-H740 COSMIC Cell Line Gene Mutation Profiles 1.0 null Intracranial aneurysm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 AKIRIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23497 CLDN19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29956 Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Defective GGT1 causes Glutathionuria (GLUTH) Reactome Pathways 2014 1.0 null Field CA3, stratum lacunosum-moleculare Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27458 membrane-enclosed lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.059054 KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE ChEA Transcription Factor Targets 2022 1.0 null FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 132.212 B4GALT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60826 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE174498,GSE174500_3_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null Butyryl-CoA HMDB Metabolites of Enzymes 1.0 null Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.498 Pelargonic acid HMDB Metabolites of Enzymes 1.0 null CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bardet-Biedl syndrome 13 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.888 GSE186707_1_v_0_hdac4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-POMQ-0008-SM-48TE7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06361 Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEMA4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23244 r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84912 Drug ADME Reactome Pathways 2024 1.0 null intermediate part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48935 ENDOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1668 intermediate stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86673 Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Olfactory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.741 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.80633 SEC24D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74631 AMP-binding enzyme C-terminal domain InterPro Predicted Protein Domain Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mitochondrial matrix GO Cellular Component Annotations 2015 1.0 null cellular lipid metabolic process GO Biological Process Annotations 2015 1.0 null STX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01859 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles 1.0 1.2508 purine ribonucleoside triphosphate binding GO Molecular Function Annotations 2015 1.0 null GSE86507,GSE86509_4_v_5_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null purine nucleoside binding GO Molecular Function Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66942 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.122 GTEX-XV7Q-0126-SM-4BRVK GTEx Tissue Sample Gene Expression Profiles 1.0 0.866809 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.5 cellular metabolic process GO Biological Process Annotations 2015 1.0 null GSE239844_7_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles 1.0 1.21579 GTEX-U4B1-0008-SM-4DXUW GTEx Tissue Sample Gene Expression Profiles 1.0 0.875741 LBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52327 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10638 PRICKLE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45007 (2E)-Decenoyl-CoA HMDB Metabolites of Enzymes 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.63836 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08779 PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.6727 AOB, internal plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85709 WHAMM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77615 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RX-A8JQ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09465 ASB13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42224 LGALS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90024 PABPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93199 GTEX-XGQ4-0126-SM-4AT4H GTEx Tissue Sample Gene Expression Profiles 1.0 1.27128 Perturb_2755_KD_C11orf67_SRP095619 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.69214 JUNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29946 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM200B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85509 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE248858_6_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null NB-4 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.083 r10 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41049 KDM1A ENCODE Transcription Factor Targets 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hexanoyl-CoA HMDB Metabolites of Enzymes 1.0 null PRXL2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39772 HIV Infections HuGE Navigator Gene-Phenotype Associations 1.0 null IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Six3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.4163 OXSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83604 SW626 DepMap CRISPR Gene Dependency 1.0 2.20169 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.79902 Vascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 Heptadecanoyl CoA HMDB Metabolites of Enzymes 1.0 null Defective UGT1A1 causes hyperbilirubinemia Reactome Pathways 2014 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null single-organism cellular process GO Biological Process Annotations 2015 1.0 null oval paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 neoplasm by anatomical site GWASdb SNP-Phenotype Associations 1.0 0.044132 CEBPD ENCODE Transcription Factor Targets 1.0 null PDF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.46588 Cortical subplate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.68221 A4/FUK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882477 ACAA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21129 Paraventricular hypothalamic nucleus, descending division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10251 ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null ASPHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05433 BECKER DepMap CRISPR Gene Dependency 1.0 8.19862 PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0559 MAX ENCODE Transcription Factor Targets 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03385 Crotonoyl-CoA HMDB Metabolites of Enzymes 1.0 null POLE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13471 HDAC2 ENCODE Transcription Factor Targets 1.0 null BCL2L10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84519 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041189 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.74148 disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.036379 fatty-acyl-CoA synthase activity GO Molecular Function Annotations 2025 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AP-1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-Q2AI-0526-SM-2I3EJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.09188 TET1-21451524-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE241701_1_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.96677 GTEX-OIZH-0226-SM-2YUMH GTEx Tissue Sample Gene Expression Profiles 1.0 0.831543 Side of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.214 FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Metabolism Reactome Pathways 2024 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Coenzyme A MW Enzyme Metabolite Associations 1.0 null Nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 Amino Acid conjugation Reactome Pathways 2014 1.0 null GTEX-QDVJ-0008-SM-48U2E GTEx Tissue Sample Gene Expression Profiles 1.0 1.10969 GSE129241_4_v_0_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null IALM CCLE Cell Line Gene CNV Profiles 1.0 2.43662 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25483 GTEX-W5WG-0008-SM-4KL25 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07278 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11398 c-acyltransferase activity GO Molecular Function Annotations 2015 1.0 null RPMI-2650 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCOA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5654 organic acid metabolic process GO Biological Process Annotations 2015 1.0 null C10 DepMap CRISPR Gene Dependency 1.0 3.8489 NCI-H1648 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.2489 oxoacid metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-S4UY-0008-SM-3NM8H GTEx Tissue Sample Gene Expression Profiles 1.0 0.861668 SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Targets 2022 1.0 null C-acyltransferase activity GO Molecular Function Annotations 2023 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Eicosanoyl-CoA HMDB Metabolites of Enzymes 1.0 null H2AZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70368 ARL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05259 Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Reactome Pathways 2014 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7212-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FCHSD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23948 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.50751 GSE183271_2_v_3_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null IL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08707 Brain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 EIF2S3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35991 VCAP DepMap CRISPR Gene Dependency 1.0 3.77032 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.840596 FOS ENCODE Transcription Factor Targets 1.0 null nucleoside phosphate metabolic process GO Biological Process Annotations 2025 1.0 null Palmityl-CoA HMDB Metabolites of Enzymes 1.0 null GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.89002 H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.942455 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.3625 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33395 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5120-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07763 fatty acid metabolic process GO Biological Process Annotations 2023 1.0 null decanoate-CoA ligase activity GO Molecular Function Annotations 2025 1.0 null Microbody membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.831 Hoxa11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.7402 Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32762 MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.588 ZNF616 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3066 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE239844_8_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6881-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF157 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.722 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 2.06107 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.09908 SUV39H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85478 Forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 UHRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28941 Field CA1, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 CREB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNAI2_01_292 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.58933 Olfactory organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.199 H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04499 NUSAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80935 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3 Rummagene Transcription Factor Associations 2026 1.0 null YMB1 CCLE Cell Line Gene CNV Profiles 1.0 2.16542 MYC_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE106661,GSE106665_2_v_3_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16894 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028153 Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WSCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88651 GSE183271_4_v_3_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null Field CA2, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 phosphorus metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.84282 C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_4504_KO_Hoxa1_SRP174196 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 14.6042 TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.499 GSE138818_1_v_0_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE182179_5_v_3_kdsr_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0451 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.71896 parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66021 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1B_HNF1B Rummagene Transcription Factor Associations 2026 1.0 null NCIH2141 CCLE Cell Line Gene CNV Profiles 1.0 1.35594 fatty acid biosynthetic process GO Biological Process Annotations 2025 1.0 null PCBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19986 Dopaminergic A13 group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19848 mantle zone of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 Abdominal obesity-metabolic syndrome 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.559 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2747 IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.83 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18679 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3409 JUND ENCODE Transcription Factor Targets 1.0 null Intrinsic component of periplasmic side of cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.673 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9277 Retrochiasmatic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89092 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCEAL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34982 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null r2 part of vestibular sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11494 EZH2 ENCODE Transcription Factor Targets 1.0 null TSSK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16493 Trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-WL46-0326-SM-3LK6Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.22993 SCG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09765 Primary somatosensory area, upper limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1562 CEBPD_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RARRES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8231 NR2F2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05829 retromammillary area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25924 Prostate adenocarcinoma_PRAD_TCGA-HC-7210-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD4-25478319-HGPS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE197564,GSE198512_0_v_1_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.9493 MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null organelle lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.063998 GTEX-XUZC-1626-SM-4BRVP GTEx Tissue Sample Gene Expression Profiles 1.0 0.884977 GTEX-Q734-1826-SM-2I3EL GTEx Tissue Sample Gene Expression Profiles 1.0 1.11229 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 253.685 496100459_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.07518 HCC1569 COSMIC Cell Line Gene Mutation Profiles 1.0 null GMFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33041 Perturb_13957_KO_YAP1_SRP194022 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.65067 ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3898 GSE120248,GSE120252_1_v_0_macf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Primary somatosensory area, barrel field, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22226 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 GSE94849_6_v_2_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null NANOG-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE228106_3_v_4_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE66014_0_v_1_perhexiline_human RummaGEO Drug Perturbation Signatures -1.0 null HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9967 Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Reactome Pathways 2014 1.0 null layer 4 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34465 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2832 UBXN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06424 Endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37415 Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5M9-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HTR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57928 GSE174701_1_v_6_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null ZNF521 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81436 lateral septal nucleus, intermedio-ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33929 cofactor metabolic process GO Biological Process Annotations 2015 1.0 null r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23668 FOXP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90057 superficial stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34593 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, mouth, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22226 NCI-H650 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 GSE130246_2_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null WDR53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56138 fatty acid biosynthetic process GO Biological Process Annotations 2023 1.0 null MTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45037 DU4475 DepMap CRISPR Gene Dependency 1.0 2.89903 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.942455 Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4372_KD_SUZ12_SRP071040 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.33629 496100610_TCx_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.28051 Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retroreuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 GTEX-WFG7-0008-SM-4LMKB GTEx Tissue Sample Gene Expression Profiles 1.0 0.853467 GSE138001_2_v_3_rorb_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-VJYA-0926-SM-4KL1N GTEx Tissue Sample Gene Expression Profiles 1.0 0.935703 Telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Brain Lower Grade Glioma_LGG_TCGA-CS-6290-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12509_KO_ERO1_ERP137480 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.30518 SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36618 intermediate stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13717 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW982 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9238 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28109 BL5214 (DOCK10) NURSA Protein Complexes 1.0 null Field CA1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08734 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7433-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75655 MYC ENCODE Transcription Factor Targets 1.0 null FADU COSMIC Cell Line Gene Mutation Profiles 1.0 null RNF141 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27533 ZNF334 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7893 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 2.0046 TET1-21451524-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null trans-Octadec-2-enoyl-CoA HMDB Metabolites of Enzymes 1.0 null PTF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55654 CNOT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82637 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.38207 INA6 CCLE Cell Line Gene CNV Profiles -1.0 -1.51242 IGF2BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12623 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A268-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null purine nucleotide binding GO Molecular Function Annotations 2015 1.0 null NANOG-21062744-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null 496100544_PCx_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.46536 Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.102365 SUPT11 CCLE Cell Line Gene CNV Profiles -1.0 -1.32009 LDAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73481 oral mucosa HPA Tissue Protein Expression Profiles -1.0 -0.82284 KCNF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59989 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7435-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0451 abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.123928 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OIZH-0926-SM-48TBR GTEx Tissue Sample Gene Expression Profiles 1.0 0.972532 GSE138945,GSE138947_0_v_1_mboat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null adenyl nucleotide binding GO Molecular Function Annotations 2015 1.0 null TC-71 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32549 Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PH-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ventral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51595 Prostate adenocarcinoma_PRAD_TCGA-J4-A83I-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1019 GTEX-U4B1-0926-SM-4DXUV GTEx Tissue Sample Gene Expression Profiles 1.0 0.935613 Stomach TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE127790_5_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OIZI-0226-SM-2XCEE GTEx Tissue Sample Gene Expression Profiles 1.0 0.879825 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1677 OGT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74179 HIC1_01_205 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.4841 GTEX-WI4N-1426-SM-3LK7H GTEx Tissue Sample Gene Expression Profiles 1.0 0.921777 Acute Myeloid Leukemia_LAML_TCGA-AB-3008-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DOV13 DepMap CRISPR Gene Dependency 1.0 3.00232 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41312 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.0 CCNI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53154 Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4401 PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-W5WG-2326-SM-3GIJH GTEx Tissue Sample Gene Expression Profiles 1.0 1.07517 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE174498,GSE174500_2_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null KDM1A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZFP90 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53576 FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Integument TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.97686 Artery disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00053 Lateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33929 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7786 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles 1.0 0.848849 Sweat gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.167 Primary somatosensory area, barrel field, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46043 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.945491 GSE248858_6_v_2_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null DCTN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68075 GTEX-P78B-0008-SM-48TE1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19909 GTEX-S341-0008-SM-4AD6D GTEx Tissue Sample Gene Expression Profiles 1.0 0.827277 PM20D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15428 PDCD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36035 GTEX-QV44-0926-SM-2S1RH GTEx Tissue Sample Gene Expression Profiles 1.0 0.868171 SNU-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32549 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9122 Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047917 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00403 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5165-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUJ4-0226-SM-4BOP8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.974778 Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SIU8-0008-SM-4BRUC GTEx Tissue Sample Gene Expression Profiles 1.0 0.969509 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null basolateral amygdaloid nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86673 MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4398-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4862 COX5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47355 TNFRSF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28211 ZNF737 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84174 ZSWIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57121 BHLHE23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35739 eicosapentaenoate biosynthesis HumanCyc Pathways 1.0 null THAP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87073 DUS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52379 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 1.75577 GSE210870_0_v_2_snai1_human RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleoside binding GO Molecular Function Annotations 2015 1.0 null Basolateral amygdalar nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.68221 intermediate stratum of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25803 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25634 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.82846 DCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31563 CXCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52706 GTEX-VUSG-1726-SM-4KKZL GTEx Tissue Sample Gene Expression Profiles 1.0 1.01294 Nonanoyl-CoA HMDB Metabolites of Enzymes 1.0 null subethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10251 NCI-H1651 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_15390_KD_E2F1_SRP399677 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.53267 Pentanoyl-CoA HMDB Metabolites of Enzymes 1.0 null SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15843 island of Calleja major Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74681 MED20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99742 RINT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90885 PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3370-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2900-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE233679_12_v_10_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 bone marrow HPA Tissue Protein Expression Profiles -1.0 -0.82284 snps GeneRIF Biological Term Annotations 1.0 null stomach HPA Tissue Protein Expression Profiles 1.0 1.38393 Perturb_1251_KO_MED1_ERP116563 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.75401 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04499 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7397-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE223893_1_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null AMP MW Enzyme Metabolite Associations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-8121-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null breast GTEx Tissue Gene Expression Profiles 1.0 0.897546 (2E)-Octenoyl-CoA HMDB Metabolites of Enzymes 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q3-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8510-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8467 DZIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96722 Stearoyl-CoA HMDB Metabolites of Enzymes 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EHMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92291 periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41269 HOXB7_01_169 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.93026 GSE200673,GSE200691_2_v_3_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFE2L2_NFE2L2 Rummagene Transcription Factor Associations 2026 1.0 null COA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27302 RBBP5 ENCODE Transcription Factor Targets 1.0 null Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.2328 mitochondrion COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 primary metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.01119 CIAO2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04757 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7903 MDAMB157 CCLE Cell Line Gene CNV Profiles -1.0 -1.90717 GSE129241_1_v_0_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null 496100451_TCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.13585 CCDC77 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3101 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCAMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27164 GTEX-OXRN-1426-SM-3LK5U GTEx Tissue Sample Gene Expression Profiles 1.0 0.878874 Overactive bladder syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.022 organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-3012-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE151612_4_v_2_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43024 GTEX-PX3G-0926-SM-48U12 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06474 CREB1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.24504 Nucleus of reunions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02623 RPA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75851 Disease Reactome Pathways 2014 1.0 null UMRC3 DepMap CRISPR Gene Dependency 1.0 3.40607 GSE205730,GSE205731_2_v_3_tazemetostat_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF652 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6609 GSE196540,GSE196542_4_v_5_dnmt3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.86833 GSE128232,GSE128233_1_v_0_phf2_human RummaGEO Gene Perturbation Signatures 1.0 null PAQR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32347 Ectorhinal area/Layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59202 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.2308 H3C10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01377 LN428 DepMap CRISPR Gene Dependency 1.0 3.65178 small molecule metabolic process GO Biological Process Annotations 2015 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877672 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.889536 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.03723 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04605 EP300 ENCODE Transcription Factor Targets 1.0 null lung HPA Tissue Protein Expression Profiles -1.0 -0.82284 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBM23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23082 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null adenyl ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null ORC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77766 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88793 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61828 C19orf53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50049 Lung adenocarcinoma_LUAD_TCGA-97-8547-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHU-011 COSMIC Cell Line Gene Mutation Profiles 1.0 null EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PATU8902 CCLE Cell Line Gene CNV Profiles 1.0 1.47539 IFI16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87871 COLO-792 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE216326_2_v_1_sulodexide_mouse RummaGEO Drug Perturbation Signatures 1.0 null ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 MDA-MB-361 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null APOBEC3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30235 GTEX-WFG8-0008-SM-4LVN6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.952257 cellular process GO Biological Process Annotations 2015 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15157 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25641 intracellular organelle lumen GO Cellular Component Annotations 2023 1.0 null SKLU1 CCLE Cell Line Gene CNV Profiles 1.0 1.41934 γ-linolenate biosynthesis HumanCyc Pathways 1.0 null POU3F1-26484290-ESCSS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XOT4-0726-SM-4GIAW GTEx Tissue Sample Gene Expression Profiles 1.0 1.17067 ABCA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42927 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2504 GTEX-S4P3-0008-SM-3NM8R GTEx Tissue Sample Gene Expression Profiles 1.0 1.16665 RABIF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07103 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4169-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LOVO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848246 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877085 AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68283 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MHHCALL4 CCLE Cell Line Gene CNV Profiles -1.0 -1.7209 NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9134 GTEX-QMRM-0008-SM-447B1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.875659 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22704 Phase II - Conjugation of compounds Reactome Pathways 2024 1.0 null RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H211 COSMIC Cell Line Gene Mutation Profiles 1.0 null SYDE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02221 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 2.01291 Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Reactome Pathways 2014 1.0 null intermediate stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33929 Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Biological oxidations Reactome Pathways 2024 1.0 null bed nucleus of the external capsule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24731 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.65226 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3739 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4814 A2058 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UPK3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89632 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4728 Uterine endometrium TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Prostate adenocarcinoma_PRAD_TCGA-CH-5791-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8448 SG231 DepMap CRISPR Gene Dependency 1.0 2.09021 Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TEAD4 ENCODE Transcription Factor Targets 1.0 null GSE135514_8_v_3_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GF-A3OT-06A-23R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COGN305 DepMap CRISPR Gene Dependency 1.0 4.12079 GSE175787_11_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null CLASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81809 medium-chain fatty acid-CoA ligase activity GO Molecular Function Annotations 2025 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.61938 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100559_FWM_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.16426 Lung squamous cell carcinoma_LUSC_TCGA-43-8115-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 FOXA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.94326 LGMN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50079 Sarcoma_SARC_TCGA-DX-A3UA-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PGLS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55631 NEUROD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87815 SU-DHL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22172 SDF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81457 GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNRF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.14844 intracellular organelle lumen GO Cellular Component Annotations 2015 1.0 null Heptanoyl-CoA HMDB Metabolites of Enzymes 1.0 null GSE233679_12_v_9_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null Manganese HMDB Metabolites of Enzymes 1.0 null Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.6212 Butanoate metabolism KEGG Pathways 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8156-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4C7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81879 CACNG6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60152 TET1 ChEA Transcription Factor Targets 1.0 null Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.2073 ATF1 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.24504 GSE169617_1_v_2_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6896 BAG6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45307 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35746 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null GSE174498,GSE174500_3_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null mitochondrial chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.283663 NCI-SNU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE121866_0_v_2_six4_human RummaGEO Gene Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3R5-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6229 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6203 Central nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.784 TRIB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10702 U266B1 CCLE Cell Line Gene CNV Profiles -1.0 -2.10206 cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04893 Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE143499_0_v_1_gata6_human RummaGEO Gene Perturbation Signatures -1.0 null Posterolateral visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05345 RCOR1 ENCODE Transcription Factor Targets 1.0 null GTEX-R55G-0226-SM-48FEI GTEx Tissue Sample Gene Expression Profiles 1.0 1.16462 HSPB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33015 LSM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.635 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.70306 Sarcoma_SARC_TCGA-IE-A4EK-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRX1_01_227 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.58544 HOXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57247 SCLC21H CCLE Cell Line Gene CNV Profiles -1.0 -1.40475 FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZH-1426-SM-4DXSR GTEx Tissue Sample Gene Expression Profiles 1.0 0.959837 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29596 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.43975 cation binding GO Molecular Function Annotations 2015 1.0 null PAX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8645 Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null liminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 carboxylic acid metabolic process GO Biological Process Annotations 2015 1.0 null Cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 septostriatal transition area (accumbens) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86673 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66201 PRXL2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5807 Throat TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9663 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63T-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung adenocarcinoma_LUAD_TCGA-93-A4JO-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Respiratory mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.407 Lauroyl-CoA HMDB Metabolites of Enzymes 1.0 null CLCN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71111 Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7063-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cell body membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.953 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.76635 Perturb_6490_KD_NONO_SRP350991 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.37781 Olfactory nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.834 COTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49699 HCC78 DepMap CRISPR Gene Dependency 1.0 4.11932 PRMT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05195 PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-12q13_11_TP63 Rummagene Transcription Factor Associations 2026 1.0 null TP53INP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50587 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FIGNL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94237 Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66942 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC-56 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JHU-029 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.85082 ETS1-21867929-TH2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null r8 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0954 ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.3184 Brain Lower Grade Glioma_LGG_TCGA-HW-8321-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NANOG-21062744-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.76787 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 42.4604 PTPN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31364 ROGDI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38113 mantle zone of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22001 OVMIU DepMap CRISPR Gene Dependency 1.0 3.59896 PRODH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3307 GSE205163,GSE205164_9_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null NPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81711 decanoate-CoA ligase activity GO Molecular Function Annotations 2023 1.0 null TOMM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61215 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 2.11817 SPIN2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65284 CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-SNMC-0008-SM-4DM5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.0106 GTEX-XUW1-0005-SM-4BOQ7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.897551 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6945-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02531 mitochondrial matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.251839 GTEX-UPK5-0008-SM-4IHJD GTEx Tissue Sample Gene Expression Profiles 1.0 1.14458 GSE146982_3_v_2_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33395 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-7662-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IQSEC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63768 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null mitochondrial part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.074134 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877672 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D1-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZM-0008-SM-4DXTQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.880002 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7006 STAT5A ENCODE Transcription Factor Targets 1.0 null CSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.25799 ZNF816 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.339 GTEX-Q2AI-1426-SM-2S1P5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.97604 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null CCDC61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90336 CoPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02942 intermediate stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03867 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.98 LDHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84392 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5813 Conjugation of salicylate with glycine Reactome Pathways 2024 1.0 null ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UHMK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27615 Propionyl-CoA HMDB Metabolites of Enzymes 1.0 null LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01083 intercalate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01979 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -0.82284 GTEX-XUJ4-0005-SM-4BOQ6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.994 eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle lumen GO Cellular Component Annotations 2015 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06682 PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Butyric acid HMDB Metabolites of Enzymes 1.0 null Metabolic disorders of biological oxidation enzymes Reactome Pathways 2014 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZDHHC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98873 Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10251 Perturb_2128_KD_DDX41_SRP309134 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.3425 Intercalated amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.68221 KINGS1 DepMap CRISPR Gene Dependency 1.0 3.27743 JUN_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Submedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.68221 NCI-H2171 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 ARID3A ENCODE Transcription Factor Targets 1.0 null Apocrine sweat gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.321 Lung squamous cell carcinoma_LUSC_TCGA-63-7022-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6493 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.448 T3M4 DepMap CRISPR Gene Dependency 1.0 3.96969 Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86673 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE153443_1_v_2_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Parathyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-SNOS-0426-SM-32PMH GTEx Tissue Sample Gene Expression Profiles 1.0 1.09159 Nose TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.438 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.90795 H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MFSD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91428 H4K20me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 periventricular stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5767 r11 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22041 intermediate stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6261 acyl-coa metabolic process GO Biological Process Annotations 2015 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45924 GTEX-RU72-1026-SM-46MUG GTEx Tissue Sample Gene Expression Profiles 1.0 0.854486 GTEX-PLZ5-1826-SM-3NB22 GTEx Tissue Sample Gene Expression Profiles 1.0 0.856667 eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GU-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.276671 ZNF660 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34856 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease Progression HuGE Navigator Gene-Phenotype Associations 1.0 null G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71068 r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07881 MAP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70969 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846228 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6183 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TCTA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85352 SARS-CoV MA15_Day4_None_GSE49262 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.65608 periventricular stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04439 Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Reactome Pathways 2014 1.0 null HLCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92098 GSE210885_2_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null JHUEM1 DepMap CRISPR Gene Dependency 1.0 5.84226 GSE210870_0_v_1_snai1_human RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPL22L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77984 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62105 PROB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65775 T47D CCLE Cell Line Gene CNV Profiles -1.0 -3.20942 TSHZ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87487 Undecanoyl-CoA HMDB Metabolites of Enzymes 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-YH-A8SY-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WDR37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96508 GSE152734,GSE152735_2_v_0_pbrm1_human RummaGEO Gene Perturbation Signatures 1.0 null NCIH841 DepMap CRISPR Gene Dependency 1.0 3.03276 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.76338 organelle part GO Cellular Component Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4899-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANKRD63 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87733 Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) Reactome Pathways 2014 1.0 null ADCK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8061 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8926 GTEX-P4PP-0926-SM-48TBZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.939228 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.6908 ZFPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51232 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.07698 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.208 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.445 TTLL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42308 GSE86507,GSE86509_7_v_5_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6087 GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 0.830673 SHMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15462 Isovaleryl-CoA HMDB Metabolites of Enzymes 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.96022 interstitial nucleus of the zona limitans Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24731 HEL COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.965653 GTEX-XBED-0008-SM-47JWO GTEx Tissue Sample Gene Expression Profiles 1.0 0.907035 coenzyme metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles 1.0 1.02114 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RBM47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.21769 ISHIKAWA(HERAKLIO)02ER- COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC4273559__F3 PFOCR Pathway Figure Associations 2024 1.0 null JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0821 KDM5B ChEA Transcription Factor Targets 1.0 null Isobutyryl-CoA HMDB Metabolites of Enzymes 1.0 null TP53BP1_KD_GSE54268_669_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7122 CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HT-29 COSMIC Cell Line Gene Mutation Profiles 1.0 null KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DVL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13396 GSE218098,GSE218099_1_v_0_tcf19_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-T6MN-0726-SM-32PML GTEx Tissue Sample Gene Expression Profiles 1.0 1.36398 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.24504 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11398 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.05619 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.0741 FEZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.14924 SRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69066 CEBPB_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4392 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null HCC2279 Klijn et al., Nat. 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