association dataset threshold value standardized value superficial stratum of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23838 VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9187 abnormal external genitalia GWASdb SNP-Phenotype Associations 1.0 0.326916 KIF5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.046 gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 endometrium HPA Tissue Protein Expression Profiles -1.0 -0.740455 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35229 support GeneRIF Biological Term Annotations 1.0 null OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34076 sclerosis of humeral diaphysis GWASdb SNP-Phenotype Associations 1.0 1.2216 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041594 MTF2 ChEA Transcription Factor Targets 1.0 null GSE240386,GSE242143_8_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Brain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7383 TestisSeminiferousTubule BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.11775 Metencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H2722 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975066 CAL72 DepMap CRISPR Gene Dependency 1.0 2.87859 Primary somatosensory area, mouth Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42818 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.937372 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20282 TestisLeydigCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55362 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.076644 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.34042 Urinary tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 bone disease GWASdb SNP-Disease Associations 1.0 0.134485 PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR Rummagene Transcription Factor Associations 2026 1.0 null r10 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24217 CEBPB ENCODE Transcription Factor Targets 1.0 null Inflammatory bowel disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.59 primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04472 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040928 GSE205163,GSE205164_2_v_6_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27481 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.64677 Prostate adenocarcinoma_PRAD_TCGA-J4-A83L-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null APBB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98765 colitis GWASdb SNP-Disease Associations 1.0 1.20161 metaphyseal sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.994954 nuclear part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044525 abnormal spermatogenesis MPO Gene-Phenotype Associations 1.0 null double-stranded RNA binding GO Molecular Function Annotations 2023 1.0 null BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26927 striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.986113 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular non-membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null NTMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97162 Esophagus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.903183 integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043181 abnormality of the urinary system GWASdb SNP-Phenotype Associations 1.0 0.359479 abnormality of the globe GWASdb SNP-Phenotype Associations 1.0 0.188989 GCT CCLE Cell Line Gene Expression Profiles -1.0 -1.56416 abnormality of the vertebral column GWASdb SNP-Phenotype Associations 1.0 0.30666 CEBPB JASPAR Predicted Transcription Factor Targets 1.0 null EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5498 SNU-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829854 rostral migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27004 Lateral element COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.974 P31-FUJ COSMIC Cell Line Gene Mutation Profiles 1.0 null SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15964 NCI-H292 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the abdomen GWASdb SNP-Phenotype Associations 1.0 0.45891 Major depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.973 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 96.2702 Hindbrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75089 USF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIM28-19339689-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.965629 Sperm flagellum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.866 Skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.499 morphological abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.166799 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Apolipoprotein B mRNA editing enzyme complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.191 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59977 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0975 inflammatory bowel disease GWASdb SNP-Disease Associations 1.0 0.439762 GSE155087_2_v_3_glutamine_mouse RummaGEO Drug Perturbation Signatures -1.0 null hypersensitivity reaction type ii disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.69843 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57911 outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.15776 Tegmental reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25637 PANC1 CCLE Cell Line Gene Expression Profiles 1.0 1.78919 MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEYA8 CCLE Cell Line Gene Expression Profiles 1.0 1.83751 ACOT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07038 hyperthyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.353395 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15217 MS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null intestinal disease GWASdb SNP-Disease Associations 1.0 0.353799 H3K9me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 inner CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12838 GSE193993_5_v_6_sstr2_human RummaGEO Gene Perturbation Signatures -1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.832 SPINT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3235 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 COLO320 CCLE Cell Line Gene Expression Profiles 1.0 1.90713 oligozoospermia MPO Gene-Phenotype Associations 1.0 null GSE175883_0_v_1_dis3_mouse RummaGEO Gene Perturbation Signatures -1.0 null MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.950531 ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SJRH30 CCLE Cell Line Gene CNV Profiles 1.0 1.42206 abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.254693 MZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.890066 alopecia areata DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.403461 H2AFZ ENCODE Transcription Factor Targets 1.0 null musculoskeletal system disease GWASdb SNP-Disease Associations 1.0 0.073819 MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4858 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null abnormality of the radius GWASdb SNP-Phenotype Associations 1.0 1.2216 intracellular membraneless organelle GO Cellular Component Annotations 2025 1.0 null r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25968 hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.829011 Spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.792 AASDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95252 CPCN CCLE Cell Line Gene Expression Profiles 1.0 2.65047 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Posterior parietal association areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05555 crohn's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.516879 epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.376494 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5028 ABCC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74625 male infertility MPO Gene-Phenotype Associations 1.0 null descent GeneRIF Biological Term Annotations 1.0 null abnormality of upper limb metaphysis GWASdb SNP-Phenotype Associations 1.0 1.2216 SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49981 male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.416195 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71U-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1456 cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null Malignant tumor of pancreas_saliva_GSE14245 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.13917 CADM1_Deficiency_GDS2027_722_mouse_Testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ETV5::HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5227 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.761874 Juvenile rheumatoid arthritis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.654 COLO205 DepMap CRISPR Gene Dependency 1.0 7.11035 NOB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9819 layer 3 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3054 SKLU1 CCLE Cell Line Gene CNV Profiles 1.0 1.75012 NCCSTCK140 CCLE Cell Line Gene Expression Profiles -1.0 -2.42975 Primary immunodeficiency disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.023 Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41475 disequilibrium GeneRIF Biological Term Annotations 1.0 null primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.195281 Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.973 LN235 CCLE Cell Line Gene Expression Profiles -1.0 -1.67484 Plagl1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.1545 shell of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76178 genomewide GeneRIF Biological Term Annotations 1.0 null GSE205163,GSE205164_2_v_0_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5032 abnormal male reproductive system physiology MPO Gene-Phenotype Associations 1.0 null Asthma (age of onset) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.509691 dorsal septopreoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.32428 Dorsal premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06662 Mesothelioma_MESO_TCGA-MQ-A4KX-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crohn's disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.594 dorsomedial preoptic area, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44905 diffuse mesangial sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 colitis GWASdb SNP-Phenotype Associations 1.0 0.426113 IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Node of Ranvier COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.862 AR ChEA Transcription Factor Targets 1.0 null Primary motor area, Layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12893 parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0816 SETDB1_KO_GSE40296_7_mouse_brain (telencephalon) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.474 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.953 Thorny excrescence COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.676 PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A Rummagene Transcription Factor Associations 2026 1.0 null shell of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48447 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5116 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.546 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8567 nucleus sagulum, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8043 Autoimmune disease of central nervous system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.174 Taenia tecta, dorsal part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49834 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null P53-22387025-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Primary somatosensory area, trunk, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91818 glucose metabolism disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.080593 Agranular insular area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82386 Perturb_17326_KO_Dis3_SRP328540 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -19.0 anteroventral periventricular preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08054 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5601 Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02881 superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.2264 REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0148 NCOR-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null abnormality of the eye GWASdb SNP-Phenotype Associations 1.0 0.146229 sublayer 6a of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6367 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0636 Melancholic depression DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.973 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.926059 Allergic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.0 bile duct disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.096224 Colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null central amygdaloid nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67598 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormal genital system morphology GWASdb SNP-Phenotype Associations 1.0 0.182143 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE153443_1_v_3_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19101 nuclear lumen GO Cellular Component Annotations 2025 1.0 null PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-106-PITX2_PITX2 Rummagene Transcription Factor Associations 2026 1.0 null Allergic rhinitis GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.4301 arthritis GWASdb SNP-Disease Associations 1.0 0.28683 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.22417 Integument TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.652 celiac disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.984321 nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_6380_KO_Snf5_SRP271283 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.84413 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54838 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IS-01A-21R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054823 multiple sclerosis GWASdb SNP-Disease Associations 1.0 1.3971 abnormal axial skeleton morphology GWASdb SNP-Phenotype Associations 1.0 0.453994 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.443 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null RMGI CCLE Cell Line Gene CNV Profiles 1.0 1.76523 decreased circulating iron level MGI Mouse Phenotype Associations 2023 1.0 null bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.42289 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975066 SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null DICER1_KO_GDS4504_582_mouse_bone marrow granulocyte-macrophage progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 Ulcerative colitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.145 primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03992 decitabine_homo sapiens_gpl570_gse30985 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.4799 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041588 alopecia DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.403461 MTHFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11315 oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213291 retropontine reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07739 SKNAS CCLE Cell Line Gene CNV Profiles 1.0 2.08554 RL95-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.846075 GPRASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78671 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01175 Perisynaptic extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.833 Rectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Varicocele DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.084 FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 281.213 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02334 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 peduncular part of dorsomedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68694 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68641 PEER CCLE Cell Line Gene CNV Profiles 1.0 2.05957 OV7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16552 wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.10415 RHOB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92174 cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.89521 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.673 RNA binding GO Molecular Function Annotations 2023 1.0 null Primary somatosensory area, upper limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59868 ventrolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.13928 GSE240439_1_v_2_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Bed nucleus of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43012 20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0425 tRNA-specific adenosine deaminase activity GO Molecular Function Annotations 2023 1.0 null HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868572 PC3 DepMap CRISPR Gene Dependency 1.0 3.30863 Arthritis, Rheumatoid HuGE Navigator Gene-Phenotype Associations 1.0 null diabetes mellitus DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.080593 Ulcerative colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.571 Peroxisomal importomer complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.795 PTPN13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98953 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.92136 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Plastron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.591 YAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5319 MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.82921 TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 ZNF138 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06558 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.338117 Colitis, Ulcerative dbGAP Gene-Trait Associations 1.0 0.50886 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null central nervous system disease GWASdb SNP-Disease Associations 1.0 0.17081 ulcerative colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.340173 pollen mother cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.194082 abnormality of the upper urinary tract GWASdb SNP-Phenotype Associations 1.0 0.355449 Uveitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.139 superficial stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11282 Pyloric region TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.526 STK24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53897 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0867 hypersensitivity reaction disease GWASdb SNP-Disease Associations 1.0 1.35834 MYC ENCODE Transcription Factor Targets 1.0 null Skeletal muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 STAT3-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE193993_5_v_3_sstr2_human RummaGEO Gene Perturbation Signatures -1.0 null Brain stem TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 european GeneRIF Biological Term Annotations 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PIGO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88012 gene expression GO Biological Process Annotations 2025 1.0 null Mitotic arrest phase fetal germ cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.14525 nuclear matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.397423 GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.059815 Spermatogenic failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.466 MZ in retrosplenial cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.833627 abnormality of long bone morphology GWASdb SNP-Phenotype Associations 1.0 1.2216 IgW immunoglobulin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.653 layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24868 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.478 diaphyseal sclerosis of the upper limbs GWASdb SNP-Phenotype Associations 1.0 1.2216 abnormal fertility/fecundity MPO Gene-Phenotype Associations 1.0 null Ulcerative colitis GWAS Catalog SNP-Phenotype Associations 1.0 0.22914 EBF1-22473956-BONE-MARROW-MOUSE ChEA Transcription Factor Targets 2022 1.0 null adenosine to inosine editing GO Biological Process Annotations 2025 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATM_knockout_75_GSE23116 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.3084 IDH3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12572 Nucleolus COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 SPI1 ChEA Transcription Factor Targets 1.0 null Male infertility due to globozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.374 Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.43326 A-VN-1203-2004(H5N1)_Day4-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.85592 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01677 disease GWASdb SNP-Disease Associations 1.0 0.050477 abnormality of upper limb bone GWASdb SNP-Phenotype Associations 1.0 1.2216 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.22408 MAPK14_knockdown_139_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.15121 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.940281 Hereditary spastic paraplegia 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.1 abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.235335 C32 COSMIC Cell Line Gene Mutation Profiles 1.0 null female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16389 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.891667 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26392 Neuron projection membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.831 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9683 Taenia tecta, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00753 ACD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7402 Hmgn1_KO_GDS5010_405_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Dyschromatosis symmetrica hereditaria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.636 level GeneRIF Biological Term Annotations 1.0 null extracellular region part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049191 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.880093 NFILZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33012 rostral paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21589 GSE158285_0_v_1_ddx5_mouse RummaGEO Gene Perturbation Signatures -1.0 null polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.848164 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.7623 BCL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98631 hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.082556 GSE240386,GSE242143_1_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88979 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Postsubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02206 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null nuclear periphery COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.319702 Large intestine lipoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.268 RNA biosynthetic process GO Biological Process Annotations 2025 1.0 null STAT1-17558387-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Type 1 diabetes autoantibodies GWAS Catalog SNP-Phenotype Associations 1.0 0.070053 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055276 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.274 MZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.826117 female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 KINGS1 DepMap CRISPR Gene Dependency 1.0 2.33326 CREB3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86677 arthritis GeneRIF Biological Term Annotations 1.0 null Superior central nucleus raphe, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12517 nucleus of the stria terminalis, medial division, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51382 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.82921 syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.215653 CHK2_KD_GSE54268_668_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Brn3a_KO_GDS1651_248_mouse_Embryonic (day 13.5) trigeminal ganglia - homozygous GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Interferon regulatory factor 5 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.629 Oogenesis phase fetal germ cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null Germ cell nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.028 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5086 rheumatoid GeneRIF Biological Term Annotations 1.0 null Agranular insular area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66148 Diabetes Mellitus, Type 1 dbGAP Gene-Trait Associations 1.0 0.406869 Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82411 EN2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0559 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Agranular insular area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18656 ZMPSTE24_Deficiency_GDS3775_506_mouse_Embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null single-multicellular organism process GO Biological Process Annotations 2015 1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32002 WDR37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96508 CORL95 CCLE Cell Line Gene Expression Profiles -1.0 -1.50475 cerebral cortex HPA Tissue Protein Expression Profiles -1.0 -1.32706 WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22282 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047265 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.865358 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null TAL1_01_217 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.40576 IRS4_KO_GDS1219_306_mouse_brown preadipocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE145639_1_v_2_adar_human RummaGEO Gene Perturbation Signatures -1.0 null anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68016 ventral posterior lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.64499 single organism reproductive process GO Biological Process Annotations 2015 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the genital system GWASdb SNP-Phenotype Associations 1.0 0.161932 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.919553 microspore TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.204878 septohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42334 biological_process GO Biological Process Annotations 2015 1.0 null primary biliary cirrhosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.18151 ELF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9927 D542MG DepMap CRISPR Gene Dependency 1.0 7.45578 FOXF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50464 ONDA8 DepMap CRISPR Gene Dependency 1.0 2.57122 UNKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52352 superficial stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28085 JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868572 mRNA_NRIP1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48833 FLI1-21867929-CD8-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormality of the clavicle GWASdb SNP-Phenotype Associations 1.0 1.2216 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.74317 HDAC2 ENCODE Transcription Factor Targets 1.0 null Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 intestinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CNBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10236 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.984078 icSARS-Cov_Day4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.38009 Inflammatory bowel disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.7 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.28576 Arthritis, Juvenile Rheumatoid HuGE Navigator Gene-Phenotype Associations 1.0 null RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4126 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44592 SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Targets 2022 1.0 null breast GTEx Tissue Gene Expression Profiles 1.0 1.26939 intermediate part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18901 496100550_TCx_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40508 hair disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.403461 SRC-2_KO_GDS5087_485_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null r8 portion of ambiguous motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23915 Satellite fibril COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.372 hypersensitivity reaction disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.686691 Catalytic step 2 spliceosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.68 STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0059 ES5 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Neck TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Asthma (adult onset) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.969897 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13483 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null graves' disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.470711 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2406 inclusion body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.210894 Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE145639_1_v_6_adar_human RummaGEO Gene Perturbation Signatures -1.0 null nymph TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.12394 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.91062 parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45193 JUN ChEA Transcription Factor Targets 1.0 null superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10936 central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043597 RNA processing GO Biological Process Annotations 2025 1.0 null Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.62632 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8594 NCIH1355 CCLE Cell Line Gene CNV Profiles 1.0 1.5322 asthenozoospermia MGI Mouse Phenotype Associations 2023 1.0 null catalytic activity GO Molecular Function Annotations 2015 1.0 null Celiac disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.276 MOLM16 CCLE Cell Line Gene Expression Profiles 1.0 1.69759 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.82211 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04397 Cecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.49253 ELF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1637 ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.991059 celiac disease GWASdb SNP-Disease Associations 1.0 0.538104 choroidal sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 COR-L32 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7014-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null KLF5-20875108-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.926561 GSE127790_13_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null interleukin-5 receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.723 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null OSC20 DepMap CRISPR Gene Dependency 1.0 4.63518 celiac GeneRIF Biological Term Annotations 1.0 null Tonsil TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1-21572438-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Posterior parietal association areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77655 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60895 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 cranial nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.254902 TCF4 ChEA Transcription Factor Targets 1.0 null MAC2A DepMap CRISPR Gene Dependency 1.0 2.60755 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.83881 outer CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.881335 abnormal fertilization MPO Gene-Phenotype Associations 1.0 null binding GO Molecular Function Annotations 2015 1.0 null Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48738 GSE150134_1_v_0_scn5a_human RummaGEO Gene Perturbation Signatures -1.0 null inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11743 chronic colitis GWASdb SNP-Phenotype Associations 1.0 0.426113 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1183 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.381379 Panuveitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.084 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3077 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.963812 rheumatoid arthritis GWASdb SNP-Phenotype Associations 1.0 0.381704 male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 MYBL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3157 pollen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.527534 RBPJ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73445 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.069009 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052188 Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.385 Dorsal peduncular area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10824 gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4826 abnormality of the lower urinary tract GWASdb SNP-Phenotype Associations 1.0 0.545307 carbohydrate metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.29118 abnormality of the hand GWASdb SNP-Phenotype Associations 1.0 1.2216 GR MotifMap Predicted Transcription Factor Targets 1.0 null ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7801 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.82921 Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87931 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.835166 ST486 CCLE Cell Line Gene Expression Profiles 1.0 1.42487 CREM ChEA Transcription Factor Targets 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.50112 juvenile rheumatoid arthritis GWASdb SNP-Disease Associations 1.0 0.720957 MYPOP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69663 intermediate stratum of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34415 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Agranular insular area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12332 sclerosis of finger phalanx GWASdb SNP-Phenotype Associations 1.0 1.2216 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Asthma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.226 Brain Lower Grade Glioma_LGG_TCGA-S9-A6U9-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.4559 Cerebellum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.973 Hippocampal mossy fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.531 abnormal male germ cell morphology MPO Gene-Phenotype Associations 1.0 null GSE126621,GSE126920_1_v_0_dppa4_mouse RummaGEO Gene Perturbation Signatures -1.0 null HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8761 HS571T CCLE Cell Line Gene CNV Profiles -1.0 -3.21002 dorsal preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74993 PCDHB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2615 abnormality of phalanx of finger GWASdb SNP-Phenotype Associations 1.0 1.2216 hippocampus HPA Tissue Protein Expression Profiles -1.0 -1.32706 JUN-21703547-K562-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null EB2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Secondary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.237 H3K9me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TDRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86232 nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61015 abnormality of limbs GWASdb SNP-Phenotype Associations 1.0 0.618833 NO11 DepMap CRISPR Gene Dependency 1.0 7.03592 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01677 Primary somatosensory area, mouth, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56836 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.626 abnormality of the ulna GWASdb SNP-Phenotype Associations 1.0 1.2216 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.901285 abnormality of the choroid GWASdb SNP-Phenotype Associations 1.0 0.404041 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.880093 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.82715 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26557 KLF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8213 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.254536 periventricular stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23762 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.77573 NCI-H2066 COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA-1_KD_GDS1245_81_mouse_megakaryocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.767 r5 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22444 LAN-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73257 linkage GeneRIF Biological Term Annotations 1.0 null nucleus sagulum, deep part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12825 r4 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28196 immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.69843 MRFAP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18813 Taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57197 FZD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56835 TE9 CCLE Cell Line Gene CNV Profiles 1.0 1.48205 teratozoospermia MGI Mouse Phenotype Associations 2023 1.0 null MEX3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80532 retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75996 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15811 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6183 VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5297 primary auditory cortex (core)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00418 integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.403461 Type 1 diabetes GWAS Catalog SNP-Phenotype Associations 1.0 0.129504 Outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.937 il21 GeneRIF Biological Term Annotations 1.0 null DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null LK-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null nucleolus GO Cellular Component Annotations 2023 1.0 null abnormality of bone mineral density GWASdb SNP-Phenotype Associations 1.0 1.05478 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042158 r6 part of ventral gigangocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4743 KMH2 CCLE Cell Line Gene Expression Profiles 1.0 2.04754 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8696 intermediate stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32972 Hemocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.97 Intercellular bridge COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.878 rna metabolic process GO Biological Process Annotations 2015 1.0 null LC1SQ DepMap CRISPR Gene Dependency 1.0 4.44536 ETV2-25802403-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Spliceosomal tri-snRNP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.711 colitis DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 Paranode region of axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.839 Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00651 abnormality of the forearm GWASdb SNP-Phenotype Associations 1.0 1.2216 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.198152 DOV13 DepMap CRISPR Gene Dependency 1.0 16.6635 Manchette COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.213 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.61714 CTCF_DEPLETION_GDS3294_97_mouse_germinal vesicle (GV) oocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.676172 E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8425 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6483 caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01142 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Seminiferous tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.396 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02086 Diabetes Mellitus, Type 1 HuGE Navigator Gene-Phenotype Associations 1.0 null Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.023 Bone disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.654 superficial stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02637 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3395 Adrenocortical carcinoma_ACC_TCGA-OR-A5KZ-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Novikoff hepatoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.688 abnormal sperm physiology MPO Gene-Phenotype Associations 1.0 null cellular metabolic process GO Biological Process Annotations 2015 1.0 null primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14167 Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM191C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71508 GSE226316_1_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null HOP-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.987367 SRC-2_Deficiency_GDS5087_270_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 REST ChEA Transcription Factor Targets 1.0 null Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 78.4762 Anteroventral periventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08054 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.674 amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02668 Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GRAMD1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.73452 RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6133 EXO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.79295 Lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.29 r1 part of intermediate nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69631 Nasal cavity disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.0 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7006 ABL1_knockdown_144_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.63818 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR Rummagene Transcription Factor Associations 2026 1.0 null Type 1 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.458 Alopecia areata GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.6 Celiac Disease DisGeNET Gene-Disease Associations 1.0 null costochondral joint sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 Flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.137 abnormality of the nephron GWASdb SNP-Phenotype Associations 1.0 0.882261 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055837 KLHL31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67319 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32263 Tube foot TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.864 deaminase activity GO Molecular Function Annotations 2025 1.0 null FAM199X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16893 irf1_17409403_nih3t3_gof_mouse_gpl81_gds2752 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -2.52818 Synaptonemal complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.353 abnormality of the male genitalia GWASdb SNP-Phenotype Associations 1.0 0.30666 inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2338 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4037 bone inflammation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.503824 abnormality of the upper arm GWASdb SNP-Phenotype Associations 1.0 0.882261 Diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.489 abnormality of the large intestine GWASdb SNP-Phenotype Associations 1.0 0.319009 superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19854 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.82921 ETS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3671 Primary somatosensory area, mouth, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17329 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.959698 Corpus epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.505 NKX2-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27229 gastrointestinal system disease GWASdb SNP-Disease Associations 1.0 0.112107 Male pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.608 SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9575 ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03521 abnormality of the thorax GWASdb SNP-Phenotype Associations 1.0 1.2216 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28824 MPV17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51393 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.412779 Central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.926059 SUZ12 ChEA Transcription Factor Targets 1.0 null Nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HT115 CCLE Cell Line Gene CNV Profiles -1.0 -1.75108 TMEM35B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86378 abnormality of the skeletal system GWASdb SNP-Phenotype Associations 1.0 0.416535 multiple sclerosis GAD Gene-Disease Associations 1.0 null Asthma GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.4301 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inflorescence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067906 abnormality of the rib cage GWASdb SNP-Phenotype Associations 1.0 1.2216 layer 5 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04759 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24786 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null interleukin GeneRIF Biological Term Annotations 1.0 null Primary somatosensory area, mouth, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24309 ZNF512 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86881 Lung squamous cell carcinoma_LUSC_TCGA-77-8143-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null developmental process GO Biological Process Annotations 2015 1.0 null CSNK1A1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80478 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042443 RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0827 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042693 JUN-21703547-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE208096_1_v_0_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null cell development GO Biological Process Annotations 2015 1.0 null neurodegenerative disease GWASdb SNP-Disease Associations 1.0 0.39752 EZH2 ENCODE Transcription Factor Targets 1.0 null ELK1::HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.261 trend GeneRIF Biological Term Annotations 1.0 null Juvenile rheumatoid arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.97 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 molecular_function GO Molecular Function Annotations 2015 1.0 null rna binding GO Molecular Function Annotations 2015 1.0 null abnormality of skeletal morphology GWASdb SNP-Phenotype Associations 1.0 0.476087 cortical sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 Kidney TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Arthritis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.654 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.857879 Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1794 cellular process involved in reproduction in multicellular organism GO Biological Process Annotations 2015 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042001 Bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.672 Autoimmune disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.023 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17864 mantle zone of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20902 Diabetes Mellitus DisGeNET Gene-Disease Associations 1.0 null NCI-H358 COSMIC Cell Line Gene Mutation Profiles 1.0 null ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bone inflammation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.764 P granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.854 intermediate stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43955 HMGN3 ENCODE Transcription Factor Targets 1.0 null Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.8315 salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.922017 immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.529994 Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3537 Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTF2-20144788-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null LMSU CCLE Cell Line Gene CNV Profiles 1.0 1.38167 ISHIKAWAHERAKLIO02ER CCLE Cell Line Gene Expression Profiles -1.0 -1.45522 Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null abnormal bone structure GWASdb SNP-Phenotype Associations 1.0 1.05478 spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.196945 Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921022 MDAMB157 CCLE Cell Line Gene Expression Profiles -1.0 -1.4575 GSE200673,GSE200691_1_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.089 CBX3 ENCODE Transcription Factor Targets 1.0 null abnormality of the costochondral junction GWASdb SNP-Phenotype Associations 1.0 1.2216 superficial stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35251 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047832 H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2565 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.48087 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.766 Primary somatosensory area, mouth, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22211 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sertoli cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.345 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75089 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3744 CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.983068 insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10865 lateral portion of the shell Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42279 GSE158456_1_v_3_furin_mouse RummaGEO Drug Perturbation Signatures 1.0 null interleukin-23 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.211933 germ cell development GO Biological Process Annotations 2015 1.0 null Spinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.008 vagus nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.372369 Rif1_KD_GDS4943_242_mouse_J1 embryonic stem cell (ESCs) line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null rna processing GO Biological Process Annotations 2015 1.0 null KMH2 CCLE Cell Line Gene CNV Profiles 1.0 1.84322 Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.204 inflammatory bowel disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03224 Bipolar Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Nasopharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCOA2_KO_GSE41558_19_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66247 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42197 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null autoimmune disease of gastrointestinal tract GWASdb SNP-Disease Associations 1.0 0.538104 HCC1954 CCLE Cell Line Gene CNV Profiles -1.0 -1.97495 musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.347144 epididymis HPA Tissue Protein Expression Profiles -1.0 -1.32706 BC-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.834 Asthma or allergic disease (pleiotropy) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.15229 KDM5A ENCODE Transcription Factor Targets 1.0 null CAL 27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21904 orbital frontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32396 phenylalanine-tRNA ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.943 BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3581 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01001 NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1841 H3K9me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Gonocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.923 lateral subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03172 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02141 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.904892 Respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 colitis, ulcerative GAD Gene-Disease Associations 1.0 null nervous system disease GWASdb SNP-Disease Associations 1.0 0.088809 Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.4639 primary metabolic process GO Biological Process Annotations 2015 1.0 null type 1 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.286877 Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 43.6306 Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.813 GATB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72717 type 1 diabetes mellitus DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.080593 SARS-BatSRBD_Day4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.96157 familybased GeneRIF Biological Term Annotations 1.0 null outer CP in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09694 MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the vertebrae GWASdb SNP-Phenotype Associations 1.0 1.2216 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9222 HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3698 Inferior colliculus, dorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05293 carbohydrate metabolism disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.080593 Female germ cell nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.967 FXR MotifMap Predicted Transcription Factor Targets 1.0 null disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.69843 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.859539 roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8207 46 XX gonadal dysgenesis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.138 Systemic lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.35 Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50278 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Hypersensitivity HuGE Navigator Gene-Phenotype Associations 1.0 null TSFM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29092 arthritis, rheumatoid; GAD Gene-Disease Associations 1.0 null Pharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Zona pellucida TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.273 interleukin-2 receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.014 Cholangitis, Sclerosing HuGE Navigator Gene-Phenotype Associations 1.0 null 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053573 glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.29118 hydrolase activity GO Molecular Function Annotations 2015 1.0 null WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66247 697 CCLE Cell Line Gene Expression Profiles 1.0 1.65787 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75089 ChIP_TRIM28_19339689 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Claustrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10792 interleukin-23 receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.539 abnormality of the abdominal organs GWASdb SNP-Phenotype Associations 1.0 0.077276 RNA processing GO Biological Process Annotations 2023 1.0 null intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.40139 Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormal gametes MPO Gene-Phenotype Associations 1.0 null Coronary Artery Disease HuGE Navigator Gene-Phenotype Associations 1.0 null Juxtaparanode region of axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.928 Perturb_15969_KO_Gata3_SRP357829 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.04058 YAP1 ChEA Transcription Factor Targets 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19921 multiple sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.191097 GK_KO_GDS1555_127_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RB1_KD_GSE50532_641_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bone inflammation disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.654 496100489_HIP_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.64474 Mesothelioma_MESO_TCGA-MQ-A4LC-01A-31R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased circulating chloride level IMPC Knockout Mouse Phenotypes 1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.021 mantle zone of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07253 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20I-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07413 Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.844555 abnormality of digit GWASdb SNP-Phenotype Associations 1.0 1.2216 FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6557 GSE205163,GSE205164_2_v_4_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.36011 neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.057826 Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4774 Primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.994 dorsal tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.9843 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.280796 nuclear lumen GO Cellular Component Annotations 2023 1.0 null Bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 OVMIU DepMap CRISPR Gene Dependency 1.0 2.19473 posterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19008 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 cochlear nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67538 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72236 using GeneRIF Biological Term Annotations 1.0 null layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46782 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.717 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829071 H3K9me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SPDEF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3204 abnormal renal morphology GWASdb SNP-Phenotype Associations 1.0 0.756889 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 Axolemma COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.848 autoimmune disease of gastrointestinal tract DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.69843 HDAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52744 IRX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97114 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040356 HK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81977 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.4956 abnormality of facial skeleton GWASdb SNP-Phenotype Associations 1.0 0.545307 Perturb_16551_KO_Ahr/Rag1_SRP159568 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.05542 ORAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40333 TM31 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 496100567_PCx_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.16139 ZFX_KO_GDS2718_150_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08074 dorsolateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12965 male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.180652 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.15407 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.15903 Median preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68016 CNOT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70434 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1666 Inferior colliculus, central nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29475 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.941481 GSE126621,GSE126920_1_v_3_dppa4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Smooth muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Mesenchymal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.651 heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null HCC-366 COSMIC Cell Line Gene Mutation Profiles 1.0 null NB1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Meiotic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.34 base conversion or substitution editing GO Biological Process Annotations 2025 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.876157 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.273 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043886 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.85073 Type 1 diabetes GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.522185 sclerosis of foot bone GWASdb SNP-Phenotype Associations 1.0 1.2216 SIX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08422 Brn3a_KO_GDS1651_247_mouse_Embryonic (day 13.5) trigeminal ganglia - heterozygous GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 YAP1-20516196-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null arthritis, rheumatoid; rheumatoid arthritis GAD Gene-Disease Associations 1.0 null Seminiferous epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.182 KASUMI2 CCLE Cell Line Gene Expression Profiles 1.0 1.41323 Inflammatory bowel disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.708 PMC4051124-1471-2164-15-256-S11.XLSX-WES_MSMD-STAT1-Target_STAT1 Rummagene Transcription Factor Associations 2026 1.0 null primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17253 male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null multicellular organismal development GO Biological Process Annotations 2015 1.0 null PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05874 Globus pallidus, external segment Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03895 Germinal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.967 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.880093 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5308 isthmic portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2752 GSE240386,GSE242143_1_v_4_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null Primary somatosensory area, upper limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.49438 sclerosis of skull base GWASdb SNP-Phenotype Associations 1.0 1.2216 HCC1833 CCLE Cell Line Gene Expression Profiles -1.0 -2.81198 impaired fertilization MPO Gene-Phenotype Associations 1.0 null VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31118 mantle zone of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18847 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.51509 MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66939 Mitochondrial derivative COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.632 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null humeral sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null Gustatory areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2353 organic cyclic compound metabolic process GO Biological Process Annotations 2015 1.0 null KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.859539 T98G DepMap CRISPR Gene Dependency 1.0 2.89071 heterocycle metabolic process GO Biological Process Annotations 2015 1.0 null PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16481 KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01175 layer 2 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14376 Colitis, Ulcerative HuGE Navigator Gene-Phenotype Associations 1.0 null abnormality of finger GWASdb SNP-Phenotype Associations 1.0 1.2216 Multiple Sclerosis HuGE Navigator Gene-Phenotype Associations 1.0 null MCM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34846 stamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.177445 USF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF610 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44176 Cerebellum BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.943779 HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01677 CCDC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95118 periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7591 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.75507 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MFE280 DepMap CRISPR Gene Dependency 1.0 5.40005 celiac disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.69843 Ankylosing spondylitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.152 Extrahepatic bile duct adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.209 SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null tRNA-specific adenosine deaminase activity GO Molecular Function Annotations 2025 1.0 null CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.0079 intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54367 vitamin c_homo sapiens_gpl570_gse11919 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ZBTB17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34667 CORL47 DepMap CRISPR Gene Dependency 1.0 4.71475 Chromatoid body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.725 GSE150134_1_v_0_fluorouracil_human RummaGEO Drug Perturbation Signatures -1.0 null demyelinating disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.185612 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868572 r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88573 medial part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44697 infertility MPO Gene-Phenotype Associations 1.0 null Sperm head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.268 MedullaOblongata BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.893374 arthritis GWASdb SNP-Phenotype Associations 1.0 0.215449 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23737 nucleolus GO Cellular Component Annotations 2025 1.0 null Gustatory areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74893 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null CDK2_knockdown_146_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.65078 Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.023 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Achene TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.553 PL18 COSMIC Cell Line Gene Mutation Profiles 1.0 null KYSE450 CCLE Cell Line Gene CNV Profiles -1.0 -1.79823 calvarial osteosclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 r7 part of the nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.30386 Thyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ulcerative colitis GWASdb SNP-Phenotype Associations 1.0 1.05066 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18419 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.845621 soft tissue HPA Tissue Protein Expression Profiles -1.0 -0.816711 DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0451 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19405 POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null WBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35975 Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14966 Primary visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39511 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.566616 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040856 Crohn's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.586 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2912 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.27309 496100369_PCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.32374 adenosine to inosine editing GO Biological Process Annotations 2023 1.0 null 20174566-TableS1 GeneSigDB Published Gene Signatures 1.0 null SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Synaptonemal structure COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.346 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ulcerative colitis DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 496100482_PCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.95897 bone inflammation disease GWASdb SNP-Disease Associations 1.0 0.251714 piP-body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.806 r2 part of prepontine raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01025 Fields of Forel Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28824 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-555-ENSG00000164093_PITX2 Rummagene Transcription Factor Associations 2026 1.0 null autoimmune disease of urogenital tract DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.18151 GSE182921_0_v_1_slit2_human RummaGEO Gene Perturbation Signatures 1.0 null TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.71754 Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.063974 Taenia tecta, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09608 Dorsal peduncular area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08054 disease of metabolism DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.080593 PPP2R5E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06543 Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.831 Demyelinating disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 medial part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25913 PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1 Rummagene Transcription Factor Associations 2026 1.0 null CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SKNO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.58832 ChIP_MTF2_20144788 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Colitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.145 inflammatory bowel disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.52343 Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.609 superficial stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34234 GRHL2-25758223-PLACENTA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3334 Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null abnormality of the metaphyses GWASdb SNP-Phenotype Associations 1.0 1.2216 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10865 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.067201 E2F1-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SK-MEL-31 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100291_TCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.15794 sclerosis of hand bone GWASdb SNP-Phenotype Associations 1.0 1.2216 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.32781 abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.25931 PAX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2146 Rheumatoid arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.843 LP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10545 cluster GeneRIF Biological Term Annotations 1.0 null Allergic rhinitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.063 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null cellular aromatic compound metabolic process GO Biological Process Annotations 2015 1.0 null disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.230409 RNA metabolic process GO Biological Process Annotations 2023 1.0 null GNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50999 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18419 GSE205163,GSE205164_2_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7853 FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 278.634 cellular nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null breast HPA Tissue Protein Expression Profiles -1.0 -0.921777 Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.88234 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null MRPL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46812 abnormality of the upper limb GWASdb SNP-Phenotype Associations 1.0 1.12171 abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.124181 periventricular stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13361 EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7122 abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.156614 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829071 ribonucleoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.21228 patchy osteosclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 Primary somatosensory area, upper limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.39931 NCIH2342 CCLE Cell Line Gene Expression Profiles 1.0 1.37588 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.963198 PCI30 DepMap CRISPR Gene Dependency 1.0 3.65813 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.888868 abnormality of the intestine GWASdb SNP-Phenotype Associations 1.0 0.248394 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.895668 microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56648 abnormal gametogenesis MPO Gene-Phenotype Associations 1.0 null TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Egg coat COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.826 FKBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61221 Tou TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.991 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6446 Testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.021 SUPHD1 CCLE Cell Line Gene CNV Profiles -1.0 -1.67723 Trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE63048_11_v_6_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868572 HCC1395 CCLE Cell Line Gene CNV Profiles 1.0 2.1726 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.0195 psoriasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.315003 abnormal cortical bone morphology GWASdb SNP-Phenotype Associations 1.0 1.2216 Respiratory allergy DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.0 Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.81 SQ1 CCLE Cell Line Gene CNV Profiles 1.0 1.72538 demyelinating disease GWASdb SNP-Disease Associations 1.0 1.3971 ZNF157 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98424 HH CCLE Cell Line Gene CNV Profiles -1.0 -1.83064 developmental process involved in reproduction GO Biological Process Annotations 2015 1.0 null testis TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 Ulcerative Colitis DisGeNET Gene-Disease Associations 1.0 null USF2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, upper limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09676 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral IC periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23838 locus GeneRIF Biological Term Annotations 1.0 null mantle zone of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26026 ATR_knockdown_140_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.64275 variation GeneRIF Biological Term Annotations 1.0 null KMS34 CCLE Cell Line Gene CNV Profiles -1.0 -2.34691 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10545 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2368 type 1 diabetes mellitus GWASdb SNP-Disease Associations 1.0 1.10764 abnormality of the uvea GWASdb SNP-Phenotype Associations 1.0 0.347713 mRNA processing(Mus musculus) WikiPathways Pathways 2014 1.0 null Inferior colliculus, external nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24077 IGROV1 DepMap CRISPR Gene Dependency 1.0 4.31625 HCC33 CCLE Cell Line Gene Expression Profiles 1.0 2.13763 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Self-reported allergy GWAS Catalog SNP-Phenotype Associations 1.0 0.377988 Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.837615 Allergic rhinitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.0 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.17377 urethral obstruction GWASdb SNP-Phenotype Associations 1.0 1.2216 Primary somatosensory area, unassigned, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11282 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.941481 Abortion, Habitual HuGE Navigator Gene-Phenotype Associations 1.0 null LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.96845 orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2632 RAB2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38721 reproductive process GO Biological Process Annotations 2015 1.0 null cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.825497 synapse-associated extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.832 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27me3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null connective tissue disease GWASdb SNP-Disease Associations 1.0 0.103451 Central linear nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25361 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.2348 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01236 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050353 SOX2-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4728 double-stranded RNA binding GO Molecular Function Annotations 2025 1.0 null posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.78731 RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7778 hypersensitivity reaction disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.69843 kiaa1109tenril2il21 GeneRIF Biological Term Annotations 1.0 null Bronchus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.745 generalized osteosclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.79281 TestisGermCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.30947 internal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.46818 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.69843 H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lipoma of colon DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.268 Asthma (childhood onset) GWAS Catalog SNP-Phenotype Associations 2025 1.0 3.52218 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.376937 sporangium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.158419 NKX2-5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6587 SNU81 CCLE Cell Line Gene Expression Profiles -1.0 -1.47762 PK45H CCLE Cell Line Gene CNV Profiles -1.0 -1.61188 arthritis, rheumatoid; coronary artery disease; crohn disease; crohn's disease; diabetes mellitus type ii; diabetes mellitus, insulin-dependent; diabetes mellitus, type 1; diabetes mellitus, type 2; hypertension; rheumatoid arthritis GAD Gene-Disease Associations 1.0 null CHAGOK1 CCLE Cell Line Gene CNV Profiles 1.0 1.78062 RCM1 DepMap CRISPR Gene Dependency 1.0 2.71449 flower TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070874 germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.40366 H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Heart TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.985794 Splenic flexure cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.293 Cardiac muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.44681 osteosclerosis of the ulna GWASdb SNP-Phenotype Associations 1.0 1.2216 intermediate stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13103 Taenia tecta, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65294 TUHR10TKB DepMap CRISPR Gene Dependency 1.0 3.05609 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null VMRCLCD DepMap CRISPR Gene Dependency 1.0 10.189 VZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.937203 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.461465 DMS-53 COSMIC Cell Line Gene Mutation Profiles 1.0 null inflammation of the large intestine GWASdb SNP-Phenotype Associations 1.0 0.426113 SUDHL6 CCLE Cell Line Gene CNV Profiles -1.0 -1.80094 abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.107404 post-traumatic stress disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.059 Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26188 periventricular stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48231 r4 part of reticulotegmental nucleus, shell portion Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33991 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.272 hypersensitivity reaction type ii disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.729357 ovary GTEx Tissue Gene Expression Profiles 1.0 1.59209 nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null GSE247764_5_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of the urethra GWASdb SNP-Phenotype Associations 1.0 0.545307 abnormality of the humerus GWASdb SNP-Phenotype Associations 1.0 1.2216 sclerotic forearm bones GWASdb SNP-Phenotype Associations 1.0 1.2216 Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75199 glomerulosclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.023 Flagellate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.098 HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6618 Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61669 SNU1105 CCLE Cell Line Gene Expression Profiles -1.0 -3.03461 496100478_HIP_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 9.76803 primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.926317 asthenozoospermia MPO Gene-Phenotype Associations 1.0 null CA-SKI COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22985 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1397 adenosine deaminase activity GO Molecular Function Annotations 2015 1.0 null Primary somatosensory area, mouth, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07618 Foxf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.9751 Cardiovascular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cd8.Tcell BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.874859 USF2 ENCODE Transcription Factor Targets 1.0 null abnormality of the fundus GWASdb SNP-Phenotype Associations 1.0 0.286711 P300-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.61062 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pi-body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.449 central nucleus of the inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12893 nephrosclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 ZNF641 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36374 ADA complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.858 H3K9me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Allergic sensitization GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.922185 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2565 BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null bed nucleus of stria terminalis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.883313 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2338 ABC1 CCLE Cell Line Gene CNV Profiles 1.0 1.38132 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null retroreuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22933 type i diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.969142 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3701 496100634_HIP_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 8.6296 amygdaloid complex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.895415 gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.164018 Parathyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CL14 CCLE Cell Line Gene Expression Profiles -1.0 -1.52623 arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19405 abnormality of the head GWASdb SNP-Phenotype Associations 1.0 0.244415 Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.22064 patchy changes of bone mineral density GWASdb SNP-Phenotype Associations 1.0 1.2216 encodes GeneRIF Biological Term Annotations 1.0 null periventricular stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99259 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.519647 Perturb_18031_KO_Dnmt3b_SRP201807 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.41627 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anomaly of the limb diaphyses GWASdb SNP-Phenotype Associations 1.0 1.2216 GSE74251_0_v_3_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null PMC5889290-koni-07-04-1412909-s001.xlsx-GSC-exo_vs_Fibro-exo_stat_sign-Gene_name_GSC Rummagene Transcription Factor Associations 2026 1.0 null SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.1634 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3299 NCIH2342 CCLE Cell Line Gene CNV Profiles -1.0 -1.47712 Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72455 LOUNH91 CCLE Cell Line Gene CNV Profiles -1.0 -1.40115 cholangitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.188326 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.987367 PAX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0964 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.6342 ZNF619 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05471 interleukin-4 receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.867 GSE214161,GSE214233_0_v_2_zmym2_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100636_FWM_probable Alzheimer's disease_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.96474 single-organism process GO Biological Process Annotations 2015 1.0 null GSE191110_0_v_1_dnajc12_human RummaGEO Gene Perturbation Signatures -1.0 null preweaning lethality, incomplete penetrance IMPC Knockout Mouse Phenotypes 1.0 null striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.99027 Vermiform appendix TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TMEM97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.002 pre-primosome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.509 provided GeneRIF Biological Term Annotations 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.088 FURIN_Deficiency_GDS3512_568_mouse_T-cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928721 psoriatic arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.6003 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.225144 pyramidal layer of taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02472 abnormality of the skull GWASdb SNP-Phenotype Associations 1.0 0.882261 H3K9me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null impaired fertilization MGI Mouse Phenotype Associations 2023 1.0 null spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.15983 COIL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22744 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BV173 CCLE Cell Line Gene Expression Profiles 1.0 1.59662 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15089 ZNF497 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92643 HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null nucleus LOCATE Predicted Protein Localization Annotations 1.0 null SW620 CCLE Cell Line Gene CNV Profiles -1.0 -1.45633 Taenia tecta, dorsal part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03436 Oral mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Oviduct TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.00457 NCIH1993 DepMap CRISPR Gene Dependency 1.0 6.95165 CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.8551 5637 CCLE Cell Line Gene Expression Profiles -1.0 -2.16483 juvenile rheumatoid arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.261599 NUMBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33373 CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA ChEA Transcription Factor Targets 2022 1.0 null MITF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9707 rheumatoid arthritis GWASdb SNP-Disease Associations 1.0 0.445414 DPY30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28789 Nose disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.0 ATP6V0A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52663 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05304 patchy sclerosis of radial diaphysis GWASdb SNP-Phenotype Associations 1.0 1.2216 GSE188721_3_v_4_mesp1_human RummaGEO Gene Perturbation Signatures 1.0 null HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921022 Autoimmune disease of musculoskeletal system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.797 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2915 NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921022 colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.340173 gene expression GO Biological Process Annotations 2023 1.0 null FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4479 Perineuronal net COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.836 S1PR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83103 clavicular sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 terete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3393 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO Molecular Function Annotations 2015 1.0 null Primary somatosensory area, unassigned Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27479 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4345-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the posterior segment of the eye GWASdb SNP-Phenotype Associations 1.0 0.286711 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64439 Intestinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.708 Pancreas TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 periventricular stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04307 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3882 medial amygdala, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08478 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6248 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WT-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112860_5_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null PARP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56103 internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.470763 Autoimmune disease of endocrine system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.597 ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 235.548 interleukin-12 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.203022 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 i-AAA complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.004 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.880093 Subcortical maternal complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.02 UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868572 NCIH23 CCLE Cell Line Gene CNV Profiles 1.0 1.58469 Eczema DisGeNET Gene-Disease Associations 1.0 null gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.871273 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4997 increased bone mineral density GWASdb SNP-Phenotype Associations 1.0 1.2216 RRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.64818 ChIP_SUZ12_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null ZNF814 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30862 KLHL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87587 interstitial nucleus of the posterior limb of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17837 Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.15245 anomaly of the upper limb diaphyses GWASdb SNP-Phenotype Associations 1.0 1.2216 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41608 EOL1 CCLE Cell Line Gene CNV Profiles 1.0 1.53523 PANC0213 CCLE Cell Line Gene Expression Profiles -1.0 -2.13875 Lacrimal gland acinar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.614 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 90.0202 SALE CCLE Cell Line Gene Expression Profiles -1.0 -2.1292 layer 2 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48377 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7463 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1447 Agranular insular area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67206 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the glomerulus GWASdb SNP-Phenotype Associations 1.0 0.882261 caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01939 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829071 external cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21978 double-stranded RNA adenosine deaminase activity GO Molecular Function Annotations 2025 1.0 null outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.38717 abnormal diaphysis morphology GWASdb SNP-Phenotype Associations 1.0 1.2216 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1371 Aicardi-Goutieres syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.369 hippocampus (hippocampal formation)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50798 TMEM230 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.39134 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.967013 NCIH2106 CCLE Cell Line Gene Expression Profiles 1.0 3.40783 Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15656 single-organism cellular process GO Biological Process Annotations 2015 1.0 null SKRC31 CCLE Cell Line Gene Expression Profiles -1.0 -2.04324 KLF15_Deficiency_GDS2687_648_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68016 YY2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6923 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4697 Sperm annulus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.869 autoimmune disease of gastrointestinal tract DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.912257 primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.66399 GSE205163,GSE205164_9_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null Spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.554 abnormality of limb bone GWASdb SNP-Phenotype Associations 1.0 1.04526 ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7401 KPNSI9S CCLE Cell Line Gene CNV Profiles -1.0 -2.09283 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.26749 r10 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02151 NUDUL1 CCLE Cell Line Gene Expression Profiles 1.0 1.46951 SP in perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30833 microsporangium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.204878 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 340.994 KIAA0319L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87175 transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23143 mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.26749 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.05597 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.023 periventricular stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21589 DUSP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49197 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.858077 Spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.995 functional abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.268922 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975797 PMC4392212-gutjnl-2013-306620-s9.pdf-12-SETDB1_SETDB1 Rummagene Transcription Factor Associations 2026 1.0 null PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null Nucleus of the lateral lemniscus, horizontal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26442 Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31219 juvenile rheumatoid arthritis GWASdb SNP-Phenotype Associations 1.0 0.621094 CPEB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67631 ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7794 rostromedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66317 Bronchoalveolar system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.981966 abnormal spermiogenesis MGI Mouse Phenotype Associations 2023 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null single-organism developmental process GO Biological Process Annotations 2015 1.0 null Autoimmune disease of musculoskeletal system DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.654 decreased germ cell number MPO Gene-Phenotype Associations 1.0 null U2-type catalytic step 2 spliceosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.081 Primary somatosensory area, unassigned, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29475 NCI-H2803 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928721 Primary motor area, Layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41783 PATU8902 CCLE Cell Line Gene CNV Profiles -1.0 -1.33237 ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975066 AKT1_knockdown_141_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.32762 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1011 nucleus GO Cellular Component Annotations 2015 1.0 null preweaning lethality, incomplete penetrance MGI Mouse Phenotype Associations 2023 1.0 null sclerosing cholangitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.337242 BICR22 CCLE Cell Line Gene CNV Profiles -1.0 -1.47965 NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.7724 intermediate stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.9843 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75089 mesangial abnormality GWASdb SNP-Phenotype Associations 1.0 1.2216 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.093 anther TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.18858 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18419 GSE215461_0_v_1_topotecan_human RummaGEO Drug Perturbation Signatures -1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041881 GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3789 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.9657 SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.927484 liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36251 Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52856 LHX1_NULL MUTATION - Ablation_GDS1748_748_mouse_Embryonic kidneys (from day E14.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054513 Lung TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PHF21B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20959 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.3373 SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928721 Birth Weight HuGE Navigator Gene-Phenotype Associations 1.0 null block GeneRIF Biological Term Annotations 1.0 null abnormal sperm number MPO Gene-Phenotype Associations 1.0 null male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.053411 OVCAR8 CCLE Cell Line Gene CNV Profiles 1.0 1.36669 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 biology GeneRIF Biological Term Annotations 1.0 null Meiotic prophase fetal germ cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null GSE146074_1_v_3_ly6e_mouse RummaGEO Gene Perturbation Signatures 1.0 null CHRNA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.705 Celiac disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.023 COLO684 DepMap CRISPR Gene Dependency 1.0 3.24565 orbital frontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.75688 abnormal reproductive system physiology MPO Gene-Phenotype Associations 1.0 null PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8987 GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CAMKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75574 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43539 oligozoospermia MGI Mouse Phenotype Associations 2023 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37754 skin HPA Tissue Protein Expression Profiles -1.0 -1.65966 Agranular insular area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23915 Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NCI-H1792 COSMIC Cell Line Gene Mutation Profiles 1.0 null Autoimmune disease of gastrointestinal tract DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.023 skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043529 POLR2A ENCODE Transcription Factor Targets 1.0 null COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975797 SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75136 RERFLCAD2 CCLE Cell Line Gene Expression Profiles 1.0 1.62792 Multiple sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.185 GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0381 gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.647721 Autoimmune disease of the nervous system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.2 Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CADM1_KO_GDS2026_301_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null central part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1826 Inferior mesenteric vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.585 HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.83627 HDAC1_KO_GDS2294_67_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null Graves' disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.602 MTF2-20144788-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Bronchial disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.226 CAMA1 CCLE Cell Line Gene Expression Profiles 1.0 1.5314 Adenosine deaminase/editase InterPro Predicted Protein Domain Annotations 1.0 null PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null Leading edge membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.793 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.305722 SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.065 Common variable immunodeficiency 8 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.223 POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6096 scale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.262645 layer 3 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18578 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Hypertension HuGE Navigator Gene-Phenotype Associations 1.0 null Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42042 Allergic Reaction DisGeNET Gene-Phenotype Associations 1.0 null ulcerative colitis GWASdb SNP-Disease Associations 1.0 1.20161 TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CORL24 CCLE Cell Line Gene Expression Profiles 1.0 2.25277 muscle GTEx Tissue Gene Expression Profiles -1.0 -0.911342 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13167 Colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.474 HCC70 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.588587 Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMBIM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19775 USF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Allergic disease (asthma, hay fever or eczema) GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.60458 Upper respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.0 anterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27464 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50695 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null Throat TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67931 USF1 ENCODE Transcription Factor Targets 1.0 null r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19553 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041463 em3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.092 SUZ12-18974828-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4733 abnormality of forearm bone GWASdb SNP-Phenotype Associations 1.0 1.2216 Rif1_KD_GDS4943_243_mouse_F1 embryonic stem cell (ESCs) line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null nucleic acid binding GO Molecular Function Annotations 2015 1.0 null Primary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.221 abnormality of male external genitalia GWASdb SNP-Phenotype Associations 1.0 0.326916 primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24771 abnormality of head or neck GWASdb SNP-Phenotype Associations 1.0 0.244415 abnormality of the ribs GWASdb SNP-Phenotype Associations 1.0 1.2216 connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.063576 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04143 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4555 Crohn Disease HuGE Navigator Gene-Phenotype Associations 1.0 null NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7235 arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.52729 CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_767_mouse_Skin - 1 Day GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null abnormal appendicular skeleton morphology GWASdb SNP-Phenotype Associations 1.0 1.13397 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.912302 Liver Cirrhosis, Biliary HuGE Navigator Gene-Phenotype Associations 1.0 null PET complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.605 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.070792 Tbx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.1803 Excretory gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 42.5078 Agranular insular area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07095 REST-19997604-NEURONS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.075 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39007 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16282 base conversion or substitution editing GO Biological Process Annotations 2023 1.0 null TOV112D CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Urinary system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleic acid metabolic process GO Biological Process Annotations 2015 1.0 null abnormality of the skull base GWASdb SNP-Phenotype Associations 1.0 1.2216 celiac disease GAD Gene-Disease Associations 1.0 null NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3198 predisposes GeneRIF Biological Term Annotations 1.0 null NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35662 GSE210655_3_v_5_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE180525,GSE180528_1_v_0_tbx3_human RummaGEO Gene Perturbation Signatures 1.0 null Integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.491 abnormal eye morphology GWASdb SNP-Phenotype Associations 1.0 0.188989 Primary somatosensory area, unassigned, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19405 Cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.973 layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05356 paraterete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11282 Condensed nuclear chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.184 hESC Derived CD184+ Endoderm Cultured Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.830539 ChIP_EZH2_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.458 EWS502 CCLE Cell Line Gene Expression Profiles -1.0 -1.93998 teratozoospermia MPO Gene-Phenotype Associations 1.0 null NFYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7173 NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2015 Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymph node TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Nose disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.024 midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55382 Gall bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 AGL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95729 mantle zone of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75399 dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.95509 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 immune system disease GWASdb SNP-Disease Associations 1.0 0.119151 B3GALT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87603 Turion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.151 Rhinitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 NCIH28 CCLE Cell Line Gene CNV Profiles -1.0 -1.43895 PHF8-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null rheumatoid arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.637102 ETS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2882 anatomical structure development GO Biological Process Annotations 2015 1.0 null cellular developmental process GO Biological Process Annotations 2015 1.0 null abnormality of radial diaphysis GWASdb SNP-Phenotype Associations 1.0 1.2216 Asthma onset (childhood vs adult) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.730103 DAOY CCLE Cell Line Gene CNV Profiles -1.0 -1.45272 Primary somatosensory area, unassigned, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47941 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056099 layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.847307 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2565 Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.287 Psoriatic arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.552 TAL1-26923725-CHIP-SEQ-HPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.382884 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75089 intermediate stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06715 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.993 PRECLH CCLE Cell Line Gene Expression Profiles -1.0 -1.78836 KRAP_Deficiency_GDS3527_566_mouse_Brown adipose tissues GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null LN215 CCLE Cell Line Gene Expression Profiles -1.0 -1.52655 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mbn-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.236 Leydig cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.041 double-stranded RNA adenosine deaminase activity GO Molecular Function Annotations 2023 1.0 null GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCOA2_KO_GDS5087_24_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3157 OPM2 CCLE Cell Line Gene CNV Profiles 1.0 1.33838 adenosine deaminase activity GO Molecular Function Annotations 2025 1.0 null magnocellular (medial) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13202 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868572 TENT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32226 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02388 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Mood disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.973 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.4028 ETV4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4926 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -1.96641 451LU COSMIC Cell Line Gene Mutation Profiles 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9961 Agranular insular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23608 ZFP41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7474 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.887501 GSE149943_1_v_0_cd8a_mouse RummaGEO Gene Perturbation Signatures 1.0 null olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.97878 Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Enterocele DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.071 abnormal sperm motility MPO Gene-Phenotype Associations 1.0 null PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE172490_5_v_3_junb_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 1 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0509 RIF1_KD_GDS4943_13_mouse_J1 ESC GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.264872 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7283 LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8214 superficial stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44697 primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.950411 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null abnormality of the kidney GWASdb SNP-Phenotype Associations 1.0 0.355449 YAP1-20516196-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Growth cone filopodium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.136 Crohn's disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.604576 male infertility MGI Mouse Phenotype Associations 2023 1.0 null Nasal cavity disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 icSARS CoV_60Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.54803 larva TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33413 superficial stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66488 urethral sphincter sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 sporangiophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.151936 PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5581 hsa-miR-329 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01828 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16481 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.889893 gastrointestinal inflammation GWASdb SNP-Phenotype Associations 1.0 0.345206 SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.880093 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21239 Primary somatosensory area, trunk, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32587 HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45838 intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.444676 acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.26266 TP53 JASPAR Predicted Transcription Factor Targets 1.0 null reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.951487 nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068628 FZR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22105 K029AX CCLE Cell Line Gene CNV Profiles -1.0 -1.36716 Multiple Sclerosis DisGeNET Gene-Disease Associations 1.0 null hypotrichosis DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.403461 USF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 CYBRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58902 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rheumatoid arthritis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.654 DUS3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20478 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.915356 KMS21BM CCLE Cell Line Gene CNV Profiles 1.0 2.41182 Interposed nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19405 Inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19782 JHH7 CCLE Cell Line Gene Expression Profiles 1.0 1.53886 H3K27me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lower respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.226 glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.338117 MPP89 CCLE Cell Line Gene Expression Profiles -1.0 -1.62506 Autoimmune disease of skin and connective tissue DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.578 urethral stenosis GWASdb SNP-Phenotype Associations 1.0 1.2216 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75089 navicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06986 P12ICHIKAWA CCLE Cell Line Gene Expression Profiles 1.0 1.59637 NO10 DepMap CRISPR Gene Dependency 1.0 2.35672 REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4706 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3627 SKNFI CCLE Cell Line Gene Expression Profiles 1.0 2.41029 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6467 XY body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.725 intermediate stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13103 vertebral body sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 Bipolar disorder GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 CAPAN1 DepMap CRISPR Gene Dependency 1.0 3.60204 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4202 MHHCALL3 CCLE Cell Line Gene Expression Profiles 1.0 1.54878 primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0825 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 IFT57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11949 diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.33503 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.67831 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.527 cell part LOCATE Predicted Protein Localization Annotations 1.0 null Celiac Disease HuGE Navigator Gene-Phenotype Associations 1.0 null diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.323365 HCC1937 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.565757 Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3467 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.41779 Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX3-1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE101239_3_v_2_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null Rhinitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.0 Agranular insular area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3267 skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053927 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 metabolic process GO Biological Process Annotations 2015 1.0 null EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4074 EP300 ENCODE Transcription Factor Targets 1.0 null adenosine deaminase activity GO Molecular Function Annotations 2023 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.326453 DICER1_KO_GDS4504_584_mouse_bone marrow granulocyte-macrophage progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Psoriasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.469 caudal interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25141 Spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.911 BXPC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.83781 Musculoskeletal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.654 layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3558 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.70639 Primary somatosensory area, nose, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12332 Digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 JVM-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null Rheumatoid Arthritis DisGeNET Gene-Disease Associations 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.04775 region GeneRIF Biological Term Annotations 1.0 null CAL27 CCLE Cell Line Gene CNV Profiles -1.0 -1.55281 there GeneRIF Biological Term Annotations 1.0 null Anxiety disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.059 hypersensitivity reaction type ii disease GWASdb SNP-Disease Associations 1.0 0.115359 secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.199032 celiac disease; colitis, ulcerative; GAD Gene-Disease Associations 1.0 null Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15513 substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.20411 MKN74 CCLE Cell Line Gene Expression Profiles 1.0 1.97037 liver cirrhosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.136327 LOU-NH91 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42601 DFCI024 CCLE Cell Line Gene Expression Profiles 1.0 1.5094 Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.175076 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 1.18704 abnormal joint morphology GWASdb SNP-Phenotype Associations 1.0 0.184204 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.919553 Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 A172 DepMap CRISPR Gene Dependency 1.0 4.76149 Double-stranded RNA-binding domain InterPro Predicted Protein Domain Annotations 1.0 null biliary tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.089882 PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17 Rummagene Transcription Factor Associations 2026 1.0 null genetic GeneRIF Biological Term Annotations 1.0 null LS1034 CCLE Cell Line Gene CNV Profiles -1.0 -2.20539 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.39975 CUL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4263 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.14 Azoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.688 RCH-ACV COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of limb bone morphology GWASdb SNP-Phenotype Associations 1.0 1.2216 Perturb_13628_OE_Fosl2_SRP200662 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.72919 spermatid development GO Biological Process Annotations 2015 1.0 null ATP5MC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88087 Sleep disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.097 Celiac disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.8 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 sclerosis of metaphyses of the upper limbs GWASdb SNP-Phenotype Associations 1.0 1.2216 decreased male germ cell number MPO Gene-Phenotype Associations 1.0 null MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0272 GSE201042_2_v_1_ptpmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.18645 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO Molecular Function Annotations 2015 1.0 null GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null populations GeneRIF Biological Term Annotations 1.0 null T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.919553 dorsolateral part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97447 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Stomach TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 LB647-SCLC COSMIC Cell Line Gene Mutation Profiles 1.0 null SYDE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18305 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null SUZ12-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ChIP_H3K27me3_17603471_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.816 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1468 diaphyseal sclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21371 JEKO1 CCLE Cell Line Gene CNV Profiles 1.0 2.42186 Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormal germ cell morphology MPO Gene-Phenotype Associations 1.0 null FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9389 rostral interstitial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03869 hsa-miR-362-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.919553 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34708 Posterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30462 Primary somatosensory area, upper limb, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68378 Nucleus of reunions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23252 GSE112860_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Autoimmune disease of gastrointestinal tract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.948 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5731 thyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.191408 USF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Spermatogenic failure 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.375 Superior central nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.278 reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042909 Connective tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.654 USF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7697 PcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0441 abnormal reproductive system morphology MPO Gene-Phenotype Associations 1.0 null ABHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90799 Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34475 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null YY1 JASPAR Predicted Transcription Factor Targets 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26937 USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null encompassing GeneRIF Biological Term Annotations 1.0 null periventricular stratum of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74993 decreased circulating chloride level MGI Mouse Phenotype Associations 2023 1.0 null RT11284 CCLE Cell Line Gene CNV Profiles -1.0 -1.35232 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U178 CCLE Cell Line Gene Expression Profiles -1.0 -1.73775 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PK59 CCLE Cell Line Gene CNV Profiles -1.0 -1.38252 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -1.32706 floret TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.129318 Gustatory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02857 SNU685 CCLE Cell Line Gene Expression Profiles -1.0 -1.51424 diabetes mellitus, type 1 GAD Gene-Disease Associations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.4337 female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01553 mantle zone of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12893 DG-75 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular organelle GO Cellular Component Annotations 2015 1.0 null SMYD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32446 plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053558 GSE205163,GSE205164_3_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.967643 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.59241 DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2611 RAB3A_KO_GDS2482_706_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null increased density of long bones GWASdb SNP-Phenotype Associations 1.0 1.2216 cellular process GO Biological Process Annotations 2015 1.0 null SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8479 Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.442 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.125697 Ileocecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.0 craniofacial osteosclerosis GWASdb SNP-Phenotype Associations 1.0 1.2216 UACC893 CCLE Cell Line Gene CNV Profiles 1.0 1.36042 Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null deaminase activity GO Molecular Function Annotations 2015 1.0 null Childhood astrocytic tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.127 PCI-30 COSMIC Cell Line Gene Mutation Profiles 1.0 null th17 GeneRIF Biological Term Annotations 1.0 null Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.454 HMC18 CCLE Cell Line Gene CNV Profiles -1.0 -1.32443 GSE240386,GSE242143_8_v_4_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2791 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32392 Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.23751 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.858254 layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.995432 spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.539 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069715 intermediate stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67497 GSKIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36269 multicellular organismal process GO Biological Process Annotations 2015 1.0 null Testis BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.09004 core of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42334 abnormality of the humeral diaphysis GWASdb SNP-Phenotype Associations 1.0 1.2216 acquired metabolic disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.080593 superficial stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69538 autoimmune disease of endocrine system DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.369628 GSE210655_3_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28275 Perireunensis nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02797 ZNF431_01_128 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59077 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42185 Vas deferens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.024 Ulcerative colitis GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.604576 20208059-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null Self-reported allergy GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.739794 ATXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30338 RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.9781 Perturb_5093_KO_Mga_SRP078684 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.94373 posterior part of anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07359 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.03035 LMO2-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mantle zone of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52065 r10 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2212 Mesothelioma_MESO_TCGA-SH-A7BC-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210662_2_v_1_znf165_human RummaGEO Gene Perturbation Signatures 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28275 decreased circulating iron level IMPC Knockout Mouse Phenotypes 1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.624 PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54633 STAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16331 superficial stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8043 MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.41858 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2329 mammalian phenotype MPO Gene-Phenotype Associations 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.884263 H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null reproductive system phenotype MPO Gene-Phenotype Associations 1.0 null DNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85424 mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10792 OLIG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23616 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3919 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.897362 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.68139 medial part of r4B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52142 MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08956 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1838 NCIH526 DepMap CRISPR Gene Dependency 1.0 2.9459 TRIM28 ChEA Transcription Factor Targets 1.0 null