association	dataset	threshold value	standardized value
Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44487
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.941771
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA1	DepMap CRISPR Gene Dependency	1.0	7.01145
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47838
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18105
PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21832
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15564
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.990875
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15943
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01166
wm115	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33283
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1263
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ntera2	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9415
COL16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72263
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08446
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0015
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	2.37817
metalloendopeptidase activity	GO Molecular Function Annotations 2023	1.0	null
PTEN_KD_GDS4759_337_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PECAPJ49	CCLE Cell Line Gene Mutation Profiles	1.0	null
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39982
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.37
MAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51628
GTEX-P4QR-0426-SM-2S1NV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835362
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RD-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96188
RKO	CCLE Cell Line Gene Mutation Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944267
Dapagliflozin_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0274797
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08403
Lung adenocarcinoma_LUAD_TCGA-55-6970-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07063
KLF5_KO_GDS3509_553_mouse_ES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9528
GF1B-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tofacitinib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0131435
BT-483	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-0326-SM-48U1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24479
HOXD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39613
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1444
NCIH2106	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50831
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9399
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.71411
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brimonidine_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0195665
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51384
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825062
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974688
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
ECI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69768
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37213
Dapagliflozin ((2S)-1,2-propanediol, hydrate)_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0222302
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03043
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43345
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
HT29	CCLE Cell Line Gene CNV Profiles	-1.0	-2.32353
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.858377
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62296
NKX3-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21575
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41743
Dimethyl fumarate_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0272887
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9569
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04709
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
B4GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14965
KYO1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.59788
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52993
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.723
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lactate (calcium)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0260848
NR3C1	ChEA Transcription Factor Targets	1.0	null
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843666
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04319
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48225
PFSK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66051
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057839
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16707
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38678
GSK1059615_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0233369
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13076
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91602
r7 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04834
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.67607
5-Azacytidine_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.012656
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10423
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913028
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9097
Sodium Salicylate_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0206303
sublayer 6b of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04002
Baicalin_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00795714
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14957
Adenine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0202974
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28673
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.427111
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03683
JM1	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6444
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.769
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887237
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838913
RPMI-2650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
decreased lean body mass	MGI Mouse Phenotype Associations 2023	1.0	null
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15935
Kidney Chromophobe_KICH_TCGA-KM-8440-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05529
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8814
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01225
H3K79me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.47311
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.290462
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65801
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03627
metabolic process	GO Biological Process Annotations 2015	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994447
Abiraterone acetate_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00600695
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58011
DMS-114	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924304
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17508
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29102
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9216
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44233
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SKMEL2	CCLE Cell Line Gene Expression Profiles	-1.0	-3.04623
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16656
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A430-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01315
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00259
ATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22684
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28059
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11523
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888742
SARS-CoV MA15_Day7-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.22965
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03532
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26699
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38552
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04171
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955062
Ezh2_deficiency_GDS2717_141_mouse_lymph node T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859051
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
TCF4-32651957-PLC/PRF/5-HUMAN-LIVER-HEPTOMA	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41234
Artesunate_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0178565
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961969
endocrine system disease	GWASdb SNP-Disease Associations	1.0	0.449115
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51043
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.13382
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HA-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889568
DMS53	DepMap CRISPR Gene Dependency	1.0	8.82176
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4344
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71231
Fingolimod (hydrochloride)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0240963
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.870685
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0211
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.515
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.7158
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963479
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999436
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.2189
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
olaparib_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0262308
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57871
Methionine adenosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.51
RPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38296
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WY7C-2426-SM-3NB2V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907023
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859087
TMEM139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03004
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17056
Perturb_2364_KD_PAK4_SRP137884	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.0885
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33373
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0073
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6919
KASUMI1	CCLE Cell Line Gene Expression Profiles	1.0	1.50194
NCIH660	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75651
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	1.07223
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16395
SNU407	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03061
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930382
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44839
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86589
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32493
protein metabolic process	GO Biological Process Annotations 2025	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
olaparib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0287693
FBXO38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21527
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06873
253JBV	CCLE Cell Line Gene Mutation Profiles	1.0	null
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acetohexamide_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0259018
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	10.5177
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.071
Vitamin K4_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.014254
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07797
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40263
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AE-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5901
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73899
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43117
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16021
HIPK1_knockout_170_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.30137
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01078
Oleic acid_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0138369
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836894
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88599
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74526
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.884142
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5195
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17834
Meckel syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4517
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79697
ECEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50517
TGM2_KD_GSE23702_716_human_NB4 cells, 72h ATRA-induced differentiation	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Hexylresorcinol_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0371072
Tucidinostat_A498	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00749869
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983359
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978497
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890766
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HIPK2_knockout_171_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.76368
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Riluzole hydrochloride_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0218502
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10564
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cns infection	GWASdb SNP-Phenotype Associations	1.0	2.12816
Triclosan_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0287283
GTEX-XBED-1626-SM-47JYN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22365
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88864
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34775
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4688
ZC3H12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26965
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Body Height	DisGeNET Gene-Phenotype Associations	1.0	null
GSE220520_5_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965353
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44178
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TP53BP1_KD_GSE54268_670_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tazarotene_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0233425
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08199
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.876481
AR	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5522
heart_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.871046
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0583
increased total body fat amount	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887915
Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16216
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27454
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81S-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OAW28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43969
18757432-Table1b	GeneSigDB Published Gene Signatures	1.0	null
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75555
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.2788
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24869
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
TRIB1_KO_GDS2944_555_mouse_Macrophages	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614974
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07528
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25553
superior parietal lobule, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11007
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92489
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09856
Simotinib_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0346455
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06908
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.889679
IQGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40728
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.14393
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21281
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42223
Plasma membrane respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970207
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78608
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866771
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11141
SHANK3_KD_GDS4759_338_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28763
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14789
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13141
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.978047
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89191
NCIH2009	CCLE Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36046
ZNF652	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06991
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41522
Geleophysic dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19926
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09944
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21513
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3998
SNU216	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49609
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.771763
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835861
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01662
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03457
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Methylprednisolone succinate_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0195751
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58262
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
8-Hydroxyquinoline_A549	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.010604
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.277444
Perturb_8829_KD_KCNN4_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25049
NUDUL1	CCLE Cell Line Gene Expression Profiles	1.0	3.4079
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Temuterkib_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.019358
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNU81	CCLE Cell Line Gene Mutation Profiles	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0802
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_18496_KD_LINC00881_SRP362016	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34197
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88551
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954494
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2327
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912829
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44915
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36555
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52427
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-6867-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43009
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.073323
TARDBP_02_80	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.24793
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04084
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98663
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18274
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40398
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.878933
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3706
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982361
Vandetanib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0149332
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
MCF7_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124858
Everolimus_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0310301
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27065
reticular formation of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28178
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92481
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8403-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5980_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.59037
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842475
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15366
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3586
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Furosemide_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0152257
OC316	CCLE Cell Line Gene Mutation Profiles	1.0	null
Entrectinib_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0239614
HEC108	CCLE Cell Line Gene Mutation Profiles	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.38937
Busulfan_A498	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0216265
Penfluridol_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.017878
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.62372
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01417
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73135
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
PMC12178937-mmc6.xlsx-D_MAFF_KDvsD_C_deg_all-gene_id_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5066
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Fra-1_KO_GDS5078_403_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF324	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1537
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73135
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40289
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51857
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36735
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.7651
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875511
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65007
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34011
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54711
Larotrectinib sulfate_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0228406
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.80861
H3K36me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	92.1189
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06802
kidney_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.964149
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29855
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.888161
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35519
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
Berbamine (dihydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0121572
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
Tofacitinib_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0270169
Piroxicam_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0181266
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00983
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98072
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22121
Tubulin inhibitor 6_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0289809
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12323
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24701
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10758
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.950426
Adrenocortical carcinoma_ACC_TCGA-OR-A5L8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of the solitary tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66995
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11917
Vemurafenib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0166983
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07894
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862889
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.955327
Lung squamous cell carcinoma_LUSC_TCGA-58-A46M-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oxaliplatin_PANC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00591293
Vortioxetine_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00862719
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70336
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2399
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05923
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.13793
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Folic acid_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0150112
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29575
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.829548
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Infigratinib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00430037
KAT2B_02_184	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65208
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.896776
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05061
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8406-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20869
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02231
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864927
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.51859
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11314
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GSE182680,GSE182683_5_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16506
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I2-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051865
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Tofacitinib_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0222229
LY2090314_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0151563
development of primary male sexual characteristics	GO Biological Process Annotations 2023	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02261
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08555
NO11	DepMap CRISPR Gene Dependency	1.0	7.81904
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040482
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Protein phosphatase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0184
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17257
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74323
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60214
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8321
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939556
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864048
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45598
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71591
testis	HPA Tissue Protein Expression Profiles	1.0	0.771763
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12489
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.868759
metallopeptidase activity	GO Molecular Function Annotations 2025	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.771763
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16278
lingual gyrus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850751
NCIH1573	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0718
NCO2	CCLE Cell Line Gene Expression Profiles	1.0	1.94873
NO-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.23934
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7583
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30545
GK_KO_GDS2610_162_mouse_Brown adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12178937-mmc6.xlsx-D_MAFF_KDvsD_C_deg_all-gene_name_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.62689
NCI-H1355	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89551
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.771763
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849839
LY2090314_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0157265
rt4	HPA Cell Line Gene Expression Profiles	1.0	0.884676
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peretinoin_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0235222
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16408
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.8583
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5740-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942697
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NF-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.02
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17611_OE_U2AF35_SRP116787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.97019
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937374
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9711
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00824
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31208
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055452
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10475
Oleic acid_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0106592
MKN74	CCLE Cell Line Gene Expression Profiles	1.0	1.43406
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827459
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903631
AT7519_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0330195
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998886
SUM-44PE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4369
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49276
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31852
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25311
SCAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85093
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Relugolix_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0236702
Neratinib_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0107948
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1911
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71173
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08367
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased bone mineral density	MGI Mouse Phenotype Associations 2023	1.0	null
SKMEL5	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850126
PMC8044433-mmc4.xlsx-Sheet1-Acute_LPS_Microglia_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-579	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
cell surface	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.200999
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70776
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51576
SW620	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90901
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I8-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DT-061_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0314397
Minodronic acid_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0212264
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15999
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Satellite fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.621
Anethole trithione_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0455024
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.86322
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VG-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.87123
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03356
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26248
Perturb_13659_KD_FOXO1_SRP192099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.2209
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09259
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830831
MTHFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05759
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60594
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1175
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.42383
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2019
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H146	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914098
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.69563
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30895
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977927
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31852
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL70	CCLE Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23817
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100605_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02314
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13181
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3391
PE/CA-PJ15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
CAMA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.854057
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9746818-jciinsight-7-152886-s077.pdf-41-ZNF518A_ZNF518A	Rummagene Transcription Factor Associations 2026	1.0	null
MFM-223	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26058
GNAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01362
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1404
Carbidopa (monohydrate)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0269988
Benztropine (mesylate)_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00370884
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41717
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22784
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6293
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17327
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
XRK3F2_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0123255
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13359
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14935
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.28872
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05232
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00924
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64942
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876055
Cilostazol_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.015478
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
male gonad development	GO Biological Process Annotations 2025	1.0	null
Pimozide_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0243922
Ralimetinib dimesylate_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0265699
Sodium Salicylate_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0132288
RF-48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Penfluridol_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0160387
RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59108
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT483	CCLE Cell Line Gene CNV Profiles	1.0	2.0044
Pralsetinib_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0278107
MCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46929
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866716
Fingolimod (hydrochloride)_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00842827
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34231
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18948
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.854057
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DANG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84241
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32649
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17989
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50813
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viral hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.929587
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44163
Adrenocortical carcinoma_ACC_TCGA-OR-A5JF-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1462
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66116
metalloendopeptidase activity	GO Molecular Function Annotations 2025	1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGF-like, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.60405
BEN	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.275
cognitive impairment	GWASdb SNP-Phenotype Associations	1.0	0.612709
RAF1_activemutant_219_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.61966
Sapanisertib_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.035405
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55008
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7355
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.967778
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3583
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23114
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1696
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03107
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Triamcinolone_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0152475
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X0-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35331
NHE3_Deficiency_GDS3323_599_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03567
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.39
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905819
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.99906
Disintegrin, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17935
tcf3_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.092349
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SW620	CCLE Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00592
Bergenin_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.021629
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29296
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr8_39096077_T_TA_b38	GTEx eQTL 2025	1.0	1.77436
sublayer 6b of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26615
Mebendazole_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0169891
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825641
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60844
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.33938
Sinomenine_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0232947
WM278	COSMIC Cell Line Gene Mutation Profiles	1.0	null
voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
Temsirolimus_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0278209
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852425
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55236
GSE147240_3_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0131
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09387
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169155_3_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62558
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1576
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46362
NALM19	CCLE Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10291819-13287_2023_3380_MOESM10_ESM.pdf-34-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853787
Bicalutamide_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0135691
Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63462
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78389
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior cingulate area, ventral part, 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22499
Tucidinostat_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0381637
JJN-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
APTO-253_AsPC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0272083
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3092
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07223
metallopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
rectum	HPA Tissue Protein Expression Profiles	1.0	0.771763
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01318
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00555
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34484
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.929116
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8639
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29E-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28879
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4751
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49443
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47871
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.361
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06889
Entorhinal area, medial part, dorsal zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10234
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860802
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73135
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.315003
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35393
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883232
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35576
Nafamostat (mesylate)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.018653
COLO684	CCLE Cell Line Gene Expression Profiles	1.0	1.70037
STYXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93348
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14724
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	3.54425
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943375
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bortezomib_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0139801
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25406
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
Bendamustine_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0178658
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3586
Activin AB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.981
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15145
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854278
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8831_KD_S100A16_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16216
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13185
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04891
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1644
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76329
LB771HNC	DepMap CRISPR Gene Dependency	1.0	4.73731
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Furosemide_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0114666
superior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.903354
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143692_0_v_1_trim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Posaconazole_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0258795
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.829548
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Belumosudil (mesylate)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.031348
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866716
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07957
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1948
PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19207
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	2.40872
Benztropine (mesylate)_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0270834
AKT1_OE_GDS2308[_473_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
icSARS CoV_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	4.78032
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06452
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15836
Megestrol_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0217599
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1417	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91605
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065206
BL-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.939159
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91454
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33468
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05796
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5283
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
proteolysis	GO Biological Process Annotations 2015	1.0	null
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0931
Prostate adenocarcinoma_PRAD_TCGA-HC-7233-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909395
(R)-Verapamil (hydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0233908
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27133
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
A549_Flavopiridol HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135096
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41318
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69224
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5883
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31292
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_1_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
Sulfatinib_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.012766
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918247
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.10075
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09686
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15058
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19945
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.053972
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.36809
intermediate stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06771
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53078
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38051
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14871
Acetohexamide_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0148647
Edoxaban (tosylate monohydrate)_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0179145
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68B-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
Sinomenine_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0258415
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14233
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Sperm head plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.243
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866938
Celecoxib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0115815
Tofacitinib_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0122489
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00692
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25785
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928841
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23445
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968854
UACC893	DepMap CRISPR Gene Dependency	1.0	2.01854
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931614
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13196
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45537
Baicalin_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00988984
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824738
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00694
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23572
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07636
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0475
c-MYC_KD_GDS2526_110_human_BT-474 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891627
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
Ivermectin_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0140295
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97352
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26804
TGF-beta_OE_GDS2974_137_mouse_corneas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QV44-1825-SM-447CF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825274
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
CA46	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.301722
HJURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30918
A549_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138865
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81357
Decitabine_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0200923
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53082
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.959
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.825066
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834695
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16227
Bexarotene_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0198249
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26615
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13974
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.454
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35222
HPAC	CCLE Cell Line Gene Expression Profiles	1.0	1.8409
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13391
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1575
EZH2	ENCODE Transcription Factor Targets	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14425
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73768
U2AF2_02_105	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.07493
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849419
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5981_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.23783
BB30HNC	DepMap CRISPR Gene Dependency	1.0	4.75607
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
icSARS CoV_54Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.921899
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63369
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986651
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947172
Voriconazole_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0189128
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09044
ELOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8271
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
NVP-BHG712_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0178029
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
meningitis	GWASdb SNP-Phenotype Associations	1.0	2.12816
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070553
SQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2885
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0445
ENTREP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67309
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15077
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992781
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02075
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24981
Belumosudil (mesylate)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0265394
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3722
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00615
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923554
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7838
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10313
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7216
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16258
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02741
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16039
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08334
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Apalutamide_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.018569
cuneus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11761
SKMEL1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13267
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53027
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73884
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.116322
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859142
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04885
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALDH18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18593
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.82
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09044
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829308
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97479
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22607
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6562
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.07758
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855708
NVP-BHG712_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.011955
SIN3B	ChEA Transcription Factor Targets	1.0	null
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.830762
Neratinib (maleate)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.020527
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
KYAE1	DepMap CRISPR Gene Dependency	1.0	2.17723
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
PPP1R15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51714
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VO-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99816
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35582
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62462
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08154
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25973
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Niclosamide (olamine)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00906352
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17312
BAY1125976_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0295608
Adenosine_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0193358
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35646
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06354
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.894
GP2D	CCLE Cell Line Gene Mutation Profiles	1.0	null
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.26474
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
PLS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76835
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918362
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31025
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMM1	CCLE Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93966
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SQ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10952034-mmc3.xlsx-Table_S2-Table_S2_Pooled_shRNA_screen_analysis_to_identify_genes_selectively_required_for_the_proliferation_of_the_cells_with_the_highest_MYC_signature_score_Related_to_Figure_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
IGROV1	CCLE Cell Line Gene Mutation Profiles	1.0	null
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0911
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921772
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Idoxuridine_HepG2/C3A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00653104
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0769
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32982
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rimonabant (Hydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0310535
Lung squamous cell carcinoma_LUSC_TCGA-56-8622-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81W-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.54627
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57461
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06981
CAL120	CCLE Cell Line Gene CNV Profiles	1.0	2.10709
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20879
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925157
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9889
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902343
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29829
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233162
GTEX-T6MO-0326-SM-32QOK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9087
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13154
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851766
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nevirapine_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0221801
MFE296	CCLE Cell Line Gene Mutation Profiles	1.0	null
A549_Danusertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012242
GSE128333_2_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10436
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712139
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842185
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956484
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49353
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ropivacaine (hydrochloride monohydrate)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0313003
NCIH1694	CCLE Cell Line Gene Mutation Profiles	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88662
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38431
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00561
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891627
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866937
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNUC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63939
MATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55026
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2911
HCC-827	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86165
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09505
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21535
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr8_39076814_A_G_b38	GTEx eQTL 2025	1.0	6.05677
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80505
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17717
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06452
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Drospirenone_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0199107
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59085
D423MG	DepMap CRISPR Gene Dependency	1.0	12.393
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845455
NLGN1_KD_GDS4759_335_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891314
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
impaired pupillary reflex	IMPC Knockout Mouse Phenotypes	1.0	null
Terfenadine_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0169019
Entorhinal area, medial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23796
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.6307
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866716
Larotrectinib_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.025895
MDA-MB-436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GPSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08744
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.958521
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991143
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	2.31422
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09473
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835531
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13331
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9898
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14062
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36046
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8288
r8 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48367
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052258
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33717
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68454
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.601
Futibatinib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0199492
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3088
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Prostate adenocarcinoma_PRAD_TCGA-EJ-5504-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.556012
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.35418
253J	CCLE Cell Line Gene Mutation Profiles	1.0	null
Omeprazole (sodium)_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0204566
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60765
hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.515725
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00884
GTEX-T6MN-0226-SM-32PMD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09044
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.912183
ZNF649	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17321
ERMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30326
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942535
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825258
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34189
HCC38	CCLE Cell Line Gene Mutation Profiles	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.971189
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
binding of sperm to zona pellucida	GO Biological Process Annotations 2025	1.0	null
APOBEC3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61893
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53731
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9669
MYOG	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07084
Cloxacillin (sodium)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.018447
GTEX-S4P3-1326-SM-4AD6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842606
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866716
Celecoxib_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0160969
Elagolix sodium_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0140001
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6364
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	2.18608
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66641
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0522
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270202
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11446
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.32891
NCIH1781	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56342
GTEX-TML8-1226-SM-32QON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1984
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE234043_0_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Entecavir (monohydrate)_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0121203
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	1.74351
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270037
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50525
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0583
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27795
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41052
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47598
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04084
LP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.27467
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04813
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.771763
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bentamapimod_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0275403
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.609
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14754
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.539
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1778
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76809
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.915154
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00224
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RC-K8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972861
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65039
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70341
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7631
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A684-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L-Eflornithine (monohydrochloride)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0199573
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3568
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.3556
Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224578
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11317
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04508
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41109
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92807
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881517
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22586
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25616
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RB-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.732677
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10974
Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47444
Brain Lower Grade Glioma_LGG_TCGA-TM-A84C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peretinoin_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0172084
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824517
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.935239
UBB_KO_GDS3906_496_mouse_Testis -  28 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3278
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48656
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919311
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12169
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62928
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41052
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9245
GSE189772,GSE189773_0_v_5_fbxo11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.591
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449116
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8343
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
GSE189336_1_v_0_nitric oxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53777
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gallic acid (hydrate)_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00676873
Ribociclib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0261037
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
breast	GTEx Tissue Gene Expression Profiles	1.0	1.16068
ACAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03574
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00395
HOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55299
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33477
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867902
GP2D	CCLE Cell Line Gene Expression Profiles	1.0	1.6526
Hexylresorcinol_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0225931
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2769
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1358
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Folic acid_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0124455
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65917
HCC70	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.42799
MEF2A_KD_GDS4759_340_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40922
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Hepatic stellate cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03045
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10859
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909904
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
endopeptidase activity	GO Molecular Function Annotations 2023	1.0	null
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5033
Fulvestrant_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00984278
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37752
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927679
PMC2742312-1479-7364-3-3-221-S3.PDF-171-PURG_PURG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40955
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02994
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.581
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05959
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.941265
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06606
5-Fluorouracil_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0235003
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12495
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.851423
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.27895
RCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06661
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1836	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Meloxicam_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0179262
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Lung squamous cell carcinoma_LUSC_TCGA-22-1002-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14686
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956652
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05224
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04002
PCGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40591
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01887
Triclosan_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0233594
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12775
Abemaciclib_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0132744
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51993
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.29342
A-VN-1203-2004(H5N1)_Day7-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.79398
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01679
superficial stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15944
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35791
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04298
Pexidartinib (hydrochloride)_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0108583
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14071
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80806
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999345
TALDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86495
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1653
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01359
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.951606
NCIH1836	CCLE Cell Line Gene Mutation Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82538
HMGN3	ENCODE Transcription Factor Targets	1.0	null
TET2_KO_GDS4287_429_mouse_LSK - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-POU2F1_POU2F1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Topotecan (hydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0440529
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69515
Glasdegib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0163013
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00183
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.99764
gonad development	GO Biological Process Annotations 2023	1.0	null
Abemaciclib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0276248
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23367
Perturb_6087_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.8443
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0121
KMS26	CCLE Cell Line Gene Mutation Profiles	1.0	null
Tofacitinib (citrate)_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0308795
SP2_02_42	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.44478
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.785927
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08113
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38431
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11546
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Malotilate_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0189234
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60019
Rimonabant_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0273569
superficial stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27833
Triamcinolone_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0239683
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70141
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
Lipoic acid_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0114551
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pralsetinib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0379513
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24929
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42283
Perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71697
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42544
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SW780	CCLE Cell Line Gene Mutation Profiles	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16841
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31645
LMNB1_02_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.66297
Canagliflozin_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0201741
Pimitespib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0123073
RFX5_02_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.01495
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71221
A-CA-04-2009(H1N1)_30Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.9883
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50689
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76785
PANC0813	CCLE Cell Line Gene CNV Profiles	1.0	1.37359
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2108
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931695
RNF2-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866716
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05207
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6327
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0628
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.899313
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.83435
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.2926
A549_BMS-911543_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148096
SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.08775
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4844-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
PANC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56408
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854278
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966466
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12832
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.918238
SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.15277
RABGGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65945
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2237
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
Busulfan_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0144761
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16638
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0426
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00318
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.93956
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06391
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.83884
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94277
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAPAN2	CCLE Cell Line Gene Expression Profiles	1.0	1.56907
NPEPPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5798
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KB-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.943419
TE15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5886
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03807
Secondary motor area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39982
PPARGC1A_KO_GDS2391_299_mouse_brain striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8246
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34461
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28487
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02781
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15847
HTT-18923047-STHdh-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07199
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07998
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6470-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Nucleus of the optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15673
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2614
Prostate adenocarcinoma_PRAD_TCGA-EJ-5509-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE99112_0_v_1_upf3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Isocorydine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0264391
chr8_39107805_G_A_b38	GTEx eQTL 2025	1.0	1.00588
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04565
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pimitespib_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0229242
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35284
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20587
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
SNU1040	CCLE Cell Line Gene Expression Profiles	-1.0	-2.43544
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85254
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73724
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11807
Prostate adenocarcinoma_PRAD_TCGA-CH-5788-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL1-21750041-SPERMATOCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64269
U2OS	CCLE Cell Line Gene Expression Profiles	1.0	1.92483
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97121
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16044
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09232
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880929
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25854
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40854
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836622
CAMA-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
inferior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07648
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C10orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82599
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991329
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44039
NarGHI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
PMC5848610-supp_gr.228809.117_Supplemental_Table_S3.xlsx-Table_S3F-Supplemental_Table_S3F_ZFX_binding_pattern_clustering_information_for_genes_with_promoters_bound_by_ZFX_related_to_Figure_2I_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Y-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60122
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34213
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47005
EWSR1	ChEA Transcription Factor Targets	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72212
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20163
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10078
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984237
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.741
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3684
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE258991_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0576
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94333
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.993318
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82096
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62047
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.99575
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.94255
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5369
CL11	DepMap CRISPR Gene Dependency	1.0	4.61003
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.447169
SLC9A3_KO_GDS3323_495_mouse_colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.65015
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38189
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02391
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04199
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84799
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43768
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01736
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04731
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1828
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DTP3_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0171509
GTEX-OHPK-0226-SM-3MJH6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936179
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9816
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67488
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0719
L540	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19488
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996238
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85408
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862037
NCIH2452	CCLE Cell Line Gene CNV Profiles	1.0	2.03177
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_11_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850273
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.31767
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.70456
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901882
H3K36me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955113
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45971
Pemigatinib_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0286478
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26959
NCIH1703	CCLE Cell Line Gene CNV Profiles	1.0	2.14084
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835855
Ritonavir_AsPC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0049755
Pemigatinib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0342661
ZNF442	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13405
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNJ11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15486
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.14568
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
Azithromycin (hydrate)_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0326597
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901617
SKMEL30	CCLE Cell Line Gene Mutation Profiles	1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sigmoid_Colon	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.00511
Bisoprolol (hemifumarate)_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.026314
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97664
COLO-800	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82425
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79396
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66679
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23613
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55319
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25611
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93486
Dimethyl fumarate_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0282725
SNU119	CCLE Cell Line Gene Expression Profiles	1.0	1.69411
NCI-H2452	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
Rucaparib (phosphate)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0184308
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00626
MOLT13	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5155
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HUES64_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.935239
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S-Adenosyl-L-methionine (disulfate tosylate)_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0142387
Talc_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.021516
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868969
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23323
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09983
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44546
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18447
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854278
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9423
Metallopeptidase, catalytic domain	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849664
intermediate stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23157
GTEX-P4PQ-0226-SM-2S1NK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25184
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59256
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_10_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.754732
Betamethasone dipropionate_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0110391
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03861
HTT-18923047-STHDH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1324
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76111
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67726
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06941
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00068
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916817
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834695
Pyridoxine_SW480	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00565346
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08117
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89005
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41786
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50067
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930546
r5 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27654
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07366
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02708
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956593
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936546
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9816
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840445
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11385
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56729
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06727
NLGN3_KD_GDS4759_336_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11217
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0049
USP34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06226
hela	HPA Cell Line Gene Expression Profiles	1.0	1.16277
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7100-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180234
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73511
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43423
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940555
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Olanzapine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0142767
Terfenadine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0205477
Outer acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.174
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10335
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.02041
Irinotecan (hydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0197257
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
HCC-15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.4
gallbladder	HPA Tissue Gene Expression Profiles	1.0	1.00628
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9451
Pemigatinib_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0239623
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPACA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66914
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Selinexor _LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00894121
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86531
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44488
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFEIFFER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39892
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23019
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.62299
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Relugolix_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0182526
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07646
Lung squamous cell carcinoma_LUSC_TCGA-43-8116-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93973
Minodronic acid_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.035868
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62411
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38774
Harringtonine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0176665
JMJD1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11792
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74323
substance dependence	GWASdb SNP-Disease Associations	1.0	0.199062
Acute Myeloid Leukemia_LAML_TCGA-AB-2819-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965196
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13981
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01642
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864236
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
T173	CCLE Cell Line Gene Expression Profiles	1.0	1.60615
Decitabine_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0212281
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.255
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833349
ludlu1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01878
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881545
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12311841-CTM2-15-e70424-s001.pdf-28-KMT2B_KMT2B	Rummagene Transcription Factor Associations 2026	1.0	null
Edoxaban (tosylate monohydrate)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0234502
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.38555
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9716
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.711975
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855372
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.664072
NR3C1_01_141	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.81
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829521
DMRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53788
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32034
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Amp_AA-TCGA-Unnamed_26_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38853
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02284
GTEX-X4XY-0926-SM-4E3JD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957951
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00595
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87048
Paclitaxel_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0284376
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6787
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Fumaric acid_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0204808
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03406
Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ritonavir_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00939238
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00715
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54407
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2061
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15564
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.647307
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU1	CCLE Cell Line Gene Expression Profiles	1.0	1.47807
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32009
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33318
SH10TC	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880221
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63447
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.02118
CDC42SE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20928
ML264_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0185722
hek293	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854278
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07199
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859142
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.13484
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943088
GTEX-OHPN-2826-SM-3LK67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09661
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60765
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78636
r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20541
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66045
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00162
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.6623
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2911
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38101
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.848697
GSE190947_2_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68577
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12106
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_15_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48793
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.602293
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7271
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01939
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14888
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48222
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
TMUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44211
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039624
Vinblastine (sulfate)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0255284
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853787
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.885475
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7103
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.7246
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.964432
CLTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95752
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935071
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02116
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46104
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866521
Paclitaxel_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00674461
A549_SL-327_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130572
Herpes simplex virus 2 mgG-1 antibody levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06199
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966571
ES5	DepMap CRISPR Gene Dependency	1.0	2.84308
NCI-H1703	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
MITF_02_85	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.32193
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02686
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.988536
Furosemide_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00896907
A549_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130863
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7076
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SW480	CCLE Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-01A-21R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25155
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00844
POT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10205
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26955
Futibatinib_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0159707
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54922
OTS514_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0219523
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SBI-0640756_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0460198
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66288
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.90712
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Clonidine (hydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0224359
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KAT6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54369
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973059
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6329
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3026
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC2D1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32719
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1324
GSE183271_4_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bicalutamide_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0281369
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69863
MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858996
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89401
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5751
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
disease	GWASdb SNP-Disease Associations	1.0	0.054867
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.929508
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.7805
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.40199
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11486
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13379
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875826
kidney disease	GWASdb SNP-Disease Associations	1.0	1.22504
SUM-229PE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.443
Nafamostat (mesylate)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0165324
GNAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58014
r7 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64686
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7013
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05649
MOLT13	CCLE Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mozavaptan_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0270449
Dexmedetomidine_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0320105
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974507
esrra_19901197_kidney_lof_mouse_gpl1261_gse16623	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.108377
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.86794
OAZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34909
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874124
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
S117	CCLE Cell Line Gene Expression Profiles	1.0	1.46762
ADAM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76793
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
angular gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.991404
decreased bone mineral density	IMPC Knockout Mouse Phenotypes	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.249665
Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11803
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
L-Thyroxine (sodium salt pentahydrate)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0248677
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58828
Gemcitabine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0392795
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.886336
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0678
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.84894
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.59063
NR2E3	JASPAR Predicted Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893853
peptidase activity	GO Molecular Function Annotations 2015	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.825165
SMC3	ENCODE Transcription Factor Targets	1.0	null
Posaconazole_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0182675
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866716
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Vemurafenib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00930745
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98378
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1938
PPARD_KO_GDS4320_619_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40948
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82606
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46235
Pyridoxine (hydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0255116
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27536
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.93541
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4533	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88447
RNF2	ChEA Transcription Factor Targets	1.0	null
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-9-ZNF135_ZNF135	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.840574
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05583
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ritonavir_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0273994
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.978577
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25442
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40433
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Irinotecan_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0150307
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30215
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Flumatinib (mesylate)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.023735
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09891
impaired pupillary reflex	MGI Mouse Phenotype Associations 2023	1.0	null
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97477
chr8_39058085_G_T_b38	GTEx eQTL 2025	1.0	3.59815
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.713
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_AT9283_10µM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128819
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.52743
waterhouse-friderichsen syndrome	GWASdb SNP-Disease Associations	1.0	2.17815
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30424
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4291
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_2_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.20361
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961856
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
occipito-temporal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.844246
MAPK14_KO_GDS2693_535_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Abemaciclib_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0164668
Glycyrrhizic acid_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0131135
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78202
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88695
chr8_39149364_C_A_b38	GTEx eQTL 2025	1.0	2.47318
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.82186
Perturb_2916_KD_FOXO1_SRP192099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02624
BI-3406_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.016305
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18513
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0441
Lenalidomide (hemihydrate)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0263147
Perturb_8825_KD_KCNN4_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE160373_1_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33559
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22107
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2689
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23226
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
LB-100_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0146941
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04166
GTEX-XPVG-2726-SM-4B66W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908914
VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE	ChEA Transcription Factor Targets 2022	1.0	null
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06374
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
J82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05763
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tranilast_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00806992
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Furosemide_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0105535
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB3A_Mutation - D77G point mutation_GDS2483_697_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCIH2342	CCLE Cell Line Gene Mutation Profiles	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.51205
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53128
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30859
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.69085
PMC12180985-BLOODA_ADV-2024-014495-mmc1.pdf-17-ZNF444_ZNF444	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898841
hsa-miR-640	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11908
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887046
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50243
Perturb_9052_KD_CACTIN_SRP075920	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.6249
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69455
Pimitespib_AsPC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0113225
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22046
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2861
GTEX-RWS6-1926-SM-47JXY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06577
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.960471
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0781
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53764
SCRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14214
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69167
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2423
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80814
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2327
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60609
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.88059
RCOR1	ChEA Transcription Factor Targets	1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881761
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833769
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24941
Peptidase M12B, propeptide	InterPro Predicted Protein Domain Annotations	1.0	null
A549_Luminespib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126072
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842198
RAD21	ENCODE Transcription Factor Targets	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
NOS-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03882
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86144
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02486
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876866
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.848572
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1017
MEG01	CCLE Cell Line Gene Expression Profiles	1.0	1.73358
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73135
H3K36me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6801
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bestatin (hydrochloride)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0130875
Medroxyprogesterone acetate_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0207595
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18112
GSE151967,GSE151968_0_v_1_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62677
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33019
GSE200839,GSE233826_2_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
decreased bone mineral content	IMPC Knockout Mouse Phenotypes	1.0	null
Celecoxib_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0202322
LOVO	CCLE Cell Line Gene Mutation Profiles	1.0	null
AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93473
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942196
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836449
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02906
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90314
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02351
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66277
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1805
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.00024
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.1946
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01061
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03493
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854278
SW837	DepMap CRISPR Gene Dependency	1.0	2.63444
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.1275
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
WTX_OE_GDS4802_34_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00025
superficial stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64528
Trifluridine_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0207171
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6116
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57573
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10646
CREBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30766
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.439123
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47272
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.21171
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17203
EFM-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0987
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.07758
Mitochondrial derivative	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19783
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59676
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFM19	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07531
GSE226233_0_v_1_pccb_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2108
Cysteamine (hydrochloride)_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0258275
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02073
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86625
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04455
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931669
MECP2_KD_GDS4759_334_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12463
GTEX-WOFL-0826-SM-3MJG1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984257
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19262
ADAM, cysteine-rich	InterPro Predicted Protein Domain Annotations	1.0	null
18757432-Table1a	GeneSigDB Published Gene Signatures	1.0	null
Thymol_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0277604
Capivasertib_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0250243
LB-100_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0287499
Raltitrexed_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0180175
Peptidase M12B, ADAM/reprolysin	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Hesperadin_10µM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178288
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	1.70105
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2853
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2766
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43668
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2324
HUPT4	DepMap CRISPR Gene Dependency	1.0	11.6058
TAK-733_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0283445
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74302
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73626
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.503
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L33	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12664
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Diammonium Glycyrrhizinate_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0266677
Ornidazole_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.028377
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04458
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36729
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051601
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25524
GTEX-QLQ7-1526-SM-2S1QA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06366
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11385
Isocorydine_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0244692
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55474
inner CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47138
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901341
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.58395
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825295
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100613_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52849
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23521
Folic acid_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0144367
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82987
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78831
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.48995
P12-ICHIKAWA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994969
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40578
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.716
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951894
Temsirolimus_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0177605
peptidase activity, acting on l-amino acid peptides	GO Molecular Function Annotations 2015	1.0	null
Temsirolimus_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0223681
RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95117
TEAD4_02_40	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965661
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42947
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7862-01A-21R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARFGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89531
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BI-78D3_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0218659
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31831
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85901
MDAMB436	CCLE Cell Line Gene Mutation Profiles	1.0	null
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11627
Perturb_8830_KD_MYEOV_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Fingolimod (hydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0207921
GK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41018
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839706
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.771763
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35539
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836895
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.073
UBB_KO_GDS3906_494_mouse_Testis -  21 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.08844
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87173
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29572
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1206
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40468
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.085
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866716
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1605
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_SRT2104_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200736
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25902
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
capan2	HPA Cell Line Gene Expression Profiles	1.0	1.27025
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040116
SNGM	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08736
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.939787
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33141
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GPR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02511
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11304
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2452	CCLE Cell Line Gene Expression Profiles	1.0	2.1338
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.24024
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838649
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40834
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7851
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969037
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55657
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897455
MDAMB157	DepMap CRISPR Gene Dependency	1.0	3.68509
WTX_OE_GDS4802_325_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5961
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8369
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945285
ST486	CCLE Cell Line Gene Mutation Profiles	1.0	null
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18978
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brimonidine_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0247299
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866716
U2AF2_02_113	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.44193
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18044
CAMA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7736
ATXN7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34728
496100663_TCx_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16323
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22312
proteolysis	GO Biological Process Annotations 2023	1.0	null
OAW28	CCLE Cell Line Gene Expression Profiles	-1.0	-2.48325
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80004
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HB-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62677
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02417
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16725
Prostate adenocarcinoma_PRAD_TCGA-CH-5768-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200673,GSE200691_2_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11843
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNCA_KO_GDS4153_444_mouse_Cerebellum - 21 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97217
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858876
BI-3406_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0194267
SKNMC	CCLE Cell Line Gene CNV Profiles	1.0	1.46285
IPC298	CCLE Cell Line Gene Mutation Profiles	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0186
Busulfan_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0224083
Regorafenib_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0274267
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25386
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865655
MAP3K7_knockdown_37_GDS5023	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.1867
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14839
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3664
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.27435
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39283
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48443
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849332
Mifepristone_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0195775
Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49913
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.02447
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02686
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892439
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08087
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53972
Thymol_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0191723
crizotinib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0146008
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.116
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5677
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
16715129-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
FMR1_KD_GDS4759_333_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE174383_4_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56535
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5426
HCC2157	CCLE Cell Line Gene Mutation Profiles	1.0	null
Ligustrazine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0382907
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9354
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.920115
PL4	DepMap CRISPR Gene Dependency	1.0	3.7663
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01077
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03601
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999345
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33946
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97469
A549_Divalproex Sodium_10µM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127433
HCC1954	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57211
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.4551
Vilanterol_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0288113
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70168
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10811
CAMA1	CCLE Cell Line Gene Mutation Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.21776
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01056
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AM38	DepMap CRISPR Gene Dependency	1.0	6.96583
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052511
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.84503
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8209
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0698
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08117
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843098
Female pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.643141
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1296
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.977
adrenal gland disease	GWASdb SNP-Disease Associations	1.0	1.72958
A549_Glesatinib(MGCD265)_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144891
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HTT	ChEA Transcription Factor Targets	1.0	null
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.07804
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05169
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07862
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.10174
Hexylresorcinol_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0257739
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35519
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81153
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.538
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZE-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.84077
HN	CCLE Cell Line Gene CNV Profiles	1.0	1.42288
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.27115
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34242
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858335
LJI308_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0133458
NLRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19733
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02769
Capmatinib_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0448929
ARHGEF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1848
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96642
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
ANKRD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00371
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853787
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26135
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epidermal growth factor-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55229
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2694
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908672
p3h3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.473
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31468
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0967
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81536
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11224
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HI-TOPK-032_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0135
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.825842
SLC33A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57832
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16136
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91129
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857652
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17526
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.19075
Kidney Chromophobe_KICH_TCGA-KN-8429-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10603
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.741
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.920203
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.59501
GPR120_KO_GDS4830_413_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17708
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1873
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054298
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850216
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.95907
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.752
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12004
MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
S117	CCLE Cell Line Gene Mutation Profiles	1.0	null
increased total body fat amount	MGI Mouse Phenotype Associations 2023	1.0	null
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.080309
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Busulfan_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0220788
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40989
H3K36me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06491
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08199
chr8_39036373_TC_T_b38	GTEx eQTL 2025	1.0	3.29173
ZFP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74846
epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.561644
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.916031
Clonidine (hydrochloride)_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.013536
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.11113
TRIM24_Deficiency_GDS3087_609_mouse_Hepatocellular carcinoma (HCC) tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Blood coagulation inhibitor, Disintegrin	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06208
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33318
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3Y4-01A-51R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bortezomib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.018941
Capmatinib_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0190076
Berberine (chloride hydrate)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0324108
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.771763
MYBL1-21750041-SPERMATOCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.432
Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07799
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15099
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11908
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.16328
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Lidocaine (hydrochloride)_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00844196
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856582
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49362
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904052
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35267
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67181
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872477
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39457
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.41764
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2423
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4904
STAT3	ENCODE Transcription Factor Targets	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.771763
Canagliflozin_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0253172
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51857
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8744
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.76314
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19659
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09246
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_35_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31025
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PH-797804_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00444007
A549_Trametinib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00976512
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846965
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24705
ETC-206_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0283451
TK10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7556
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86444
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40876
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36951
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.906727
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33471
reticular formation of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68652
precuneus, left, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955291
Pentamidine (isethionate)_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00572424
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO684	DepMap CRISPR Gene Dependency	1.0	14.325
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.43338
PANC-08-13	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
Integrin alpha6-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98203
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11836
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
NCIH929	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
lung_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26281
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.85898
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21103
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10075
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11551
MO-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863416
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.20108
Necrosis	CTD Gene-Disease Associations	1.0	1.07234
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316836
Idarubicin (hydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.011979
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91129
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ML264_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0152103
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.20593
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1252	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of higher mental function	GWASdb SNP-Phenotype Associations	1.0	0.262123
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.43111
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
MEF2D_KD_GDS4759_339_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Adagrasib_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0198051
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88124
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.03715
Canagliflozin_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0237125
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10712
ion binding	GO Molecular Function Annotations 2015	1.0	null
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04645
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36244
HT115	CCLE Cell Line Gene Mutation Profiles	1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88576
Macitentan_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0143677
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73694
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NVP-BHG712_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0197021
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21811
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Awn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3431
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74984
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7875
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02781
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48136
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7368
Tofacitinib (citrate)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0219498
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-01A-21R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
proteolysis	GO Biological Process Annotations 2025	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01608
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42712
GSE217363_6_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
endopeptidase activity	GO Molecular Function Annotations 2025	1.0	null
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.21695
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
stomach_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.863619
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMS454	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64099
TRAPPC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12221
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15949
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883181
kidney_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.867861
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45003
Belumosudil_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0152289
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829716
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21871
Ranolazine_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0270899
Prostate adenocarcinoma_PRAD_TCGA-XA-A8JR-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
GSE174383_4_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59058
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20008
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37039
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.56227
GSK1059615_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0276495
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09928
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01619
NCIH2347	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02483
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.29342
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930943
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-2426-SM-2TC5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914052
Elagolix sodium_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0147843
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70296
Rutin (trihydrate)_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0121731
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3805
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.061144
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05343
OCILY19	CCLE Cell Line Gene CNV Profiles	1.0	1.48228
TET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43116
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36341
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0967
D-392MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
p2 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03226
SRSF3_02_127	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.16408
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.989551
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tolcapone_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0258952
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952125
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8567
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53909
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0763
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89928
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3758
Resveratrol_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0266072
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874959
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SERBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24628
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.876947
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7435
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23933
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0479
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9-ING-41_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0227126
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35588
OCIAML5	CCLE Cell Line Gene Expression Profiles	1.0	2.0503
FGFR1_activemutant_58_GSE17916	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.072
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881898
Verapamil_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0225655
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12708
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866716
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7345
Lung squamous cell carcinoma_LUSC_TCGA-66-2742-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Phenytoin (sodium)_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0293994
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.14013
Cabozantinib (S-malate)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0130619
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.53873
Adenosine_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0222404
496100345_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28877
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6023-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38262
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07674
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Rucaparib (phosphate)_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00282884
PF-06260933_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0254976
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74664
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0226-SM-3MJG6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955458
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN	CCLE Cell Line Gene Expression Profiles	1.0	1.3801
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17257
Fenofibrate_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0265959
NCIH810	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89156
G-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSK1059615_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0182987
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846405
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883181
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46313
PMC9746818-jciinsight-7-152886-s077.pdf-41-ENSG00000177853_ZNF518A	Rummagene Transcription Factor Associations 2026	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.070373
SIN3A	ENCODE Transcription Factor Targets	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4228
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05718
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
decreased lean body mass	IMPC Knockout Mouse Phenotypes	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01624
SNU1197	CCLE Cell Line Gene Expression Profiles	1.0	1.48304
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0467
male gonad development	GO Biological Process Annotations 2023	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74011
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.46128
Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835569
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17844
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19764
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92265
decreased bone mineral content	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824131
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04165
HCC1500	CCLE Cell Line Gene Expression Profiles	1.0	1.80575
Neratinib_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0334748
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35613
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13967
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44959
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907781
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12791
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Vaginal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972752
BLCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9307
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999345
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBC1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23705
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68781
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54401
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45268
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05947
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53394
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16619
ETC-206_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.034357
IHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00228
COLO 849	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.956172
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.68137
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.719876
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04767
REST	ChEA Transcription Factor Targets	1.0	null
MFH-INO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04766
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834573
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67958
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412771
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ataluren_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0265941
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12052
STAT2_02_18	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.66297
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.25875
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45268
DCHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45654
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31915
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08938
AZD-8055_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0215327
Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1_KO_GSE43695_681_mouse_lung, bleomycin treated	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Acid phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.084
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYBL1	ChEA Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839784
CBX2_KO_GDS4445_354_mouse_E11.5 XY embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Rapamycin_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0190594
development of primary male sexual characteristics	GO Biological Process Annotations 2025	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15389
CHML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51067
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54274
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040068
ONS-76	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.42834
Secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46144
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.44736
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
chr8_39077064_C_T_b38	GTEx eQTL 2025	1.0	2.66878
Perturb_8302_KD_RBM22_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.12474
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158815_5_v_0_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08109
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03656
GSE83145_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06356
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32134
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0352
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LP1	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76586
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.771763
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03698
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08202
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22136
mantle zone of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04939
metalloendopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1769
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.9662
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0226-SM-4AT4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920828
SNUC2A	CCLE Cell Line Gene Mutation Profiles	1.0	null
SLR25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48097
Niclosamide (olamine)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0139202
Epirubicin (hydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0195374
Meckel syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.579
Chondrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10424
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6373-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196117_6_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fog2_KO_GDS3659_152_mouse_adult heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
icSARA deltaORF6_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.61531
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MU-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.34469
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22447
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.903579
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38178
RPMI 2650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59165
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2856
BI-3406_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0255411
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PEX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04284
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06222
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922583
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27355
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01105
SCML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3904
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.960471
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2098
ZC3H11A_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43422
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09382
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.01387
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836808
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66397
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.989965
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42961
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC827	CCLE Cell Line Gene Mutation Profiles	1.0	null
CDK8_knockdown_147_GSE32108	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.5839
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10319
gonad development	GO Biological Process Annotations 2025	1.0	null
SERPINB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19324
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DTP3_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0162693
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10508
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844157
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40646
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.952158
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sieve plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38895
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95651
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3361
APTO-253_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0189206
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16957
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6738
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26692
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1404
cellular_component	GO Cellular Component Annotations 2015	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17327
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_RNF2_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932805
P3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25128
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.840574
AMER1_OE_GDS4802_549_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9161
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44441
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07205
Folic acid_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0358188
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.771763
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vinblastine (sulfate)_HepG2/C3A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0105018
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881431
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17062
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39033
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03303
59M	CCLE Cell Line Gene CNV Profiles	1.0	1.75259
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61564
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2716
Aliskiren_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.020413
Fluvoxamine_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0348971
ZNF143_02_59	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.01282
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
4EGI-1_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0293861
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216419
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07201
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9455
AZD-7648_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.034273
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
Trimetrexate_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0298569
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96155
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW403	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46572
SARS-CoV MA15_Day2-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.42387
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926399
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15534
Bosentan (hydrate)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0288778
Acute Myeloid Leukemia_LAML_TCGA-AB-2859-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16903
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05512
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5157
DLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43857
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60277
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944117
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03847
SKRC31	CCLE Cell Line Gene Expression Profiles	1.0	1.35191
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931901
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09387
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858841
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67643
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14978
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25117
Kidney Chromophobe_KICH_TCGA-KN-8418-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87244
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.999705
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896531
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860683
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4R-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100643_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20006
Encorafenib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0194161
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837953
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54649
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26509
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64282
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.946019
EXOSC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78429
L-Eflornithine (monohydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0154405
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01777
ZNF366	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16865
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984037
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67958
PSME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3486
HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anethole trithione_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0344066
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01153
Hexylresorcinol_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0231802
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.19796
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02304
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276846
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51599
metallopeptidase activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89389
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48175
Megestrol_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0259475
BNIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2349
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53099
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0047
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9801
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21413
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111725
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63877
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052511
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13795
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.925208
MCF7	CCLE Cell Line Gene Expression Profiles	1.0	1.52149
BT-483	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2247
CAL-120	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
EFM19	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70085
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97477
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40657
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04611
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IL17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13817
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46532
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055814
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53438
GSE114685_1_v_0_grin2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17229
EE-04-QG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265934
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNUC5	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Crizotinib (hydrochloride)_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0158318
PATU8988T	DepMap CRISPR Gene Dependency	1.0	3.10371
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01727
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF2-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.95234
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
YPEL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95307
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57637
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.643263
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3652
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13824
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903272
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02129
alcohol dependence	GWASdb SNP-Disease Associations	1.0	0.500478
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01079
Fatty Liver	CTD Gene-Disease Associations	1.0	1.17464
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25845
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14437
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297641
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869878
SW48	CCLE Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L-Thyroxine (sodium salt pentahydrate)_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0201148
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18561
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01456
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3844
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNUC4	CCLE Cell Line Gene Mutation Profiles	1.0	null
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94487
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03451
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21079
Lung squamous cell carcinoma_LUSC_TCGA-98-8023-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sperm-egg recognition	GO Biological Process Annotations 2025	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.80777
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985207
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	1.37918
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A195-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null