association	dataset	threshold value	standardized value
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.974792
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61626
J82	DepMap CRISPR Gene Dependency	1.0	2.00019
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0141
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40616
Ascites tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.4541
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65115
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11467
GATA2	ENCODE Transcription Factor Targets	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02098
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17461
GSE72491_0_v_1_pcbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98526
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62265
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32156
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09737
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OUMS23	DepMap CRISPR Gene Dependency	1.0	3.17341
MEG01	CCLE Cell Line Gene Expression Profiles	1.0	1.54425
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5B	ChEA Transcription Factor Targets	1.0	null
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25418
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU283	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77692
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.86713
VCPKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84921
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10126
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RERF-LC-MS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60268
VAChT_KD_GDS4325_361_mouse_Heart from C57BL/6 males	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5994
KCNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07069
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10884
COMMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5866
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26154
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
layer 2 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1664
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30211
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.14074
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18944
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10257
hsa-miR-4753-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Osteogenesis imperfecta type 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Lung squamous cell carcinoma_LUSC_TCGA-85-7697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEV_60Day_None_GSE53731	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.82833
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF569	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59402
HDAC2	ENCODE Transcription Factor Targets	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23752
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14205
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.226
FOXA2	ChEA Transcription Factor Targets	1.0	null
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45477
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974305
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89334
PRDM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18467
hsa-miR-4465	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-1.57179
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MOZ/MORF histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0238
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36189
KYSE270	DepMap CRISPR Gene Dependency	1.0	2.00354
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981379
CCNT2	ENCODE Transcription Factor Targets	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59902
SLC35C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00706
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55534
SW1463	CCLE Cell Line Gene Expression Profiles	1.0	1.50868
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89839
SYNCRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65202
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2271
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039953
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.87088
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE183327,GSE183328_3_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68981
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66711
PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S2-Supplementary_Table_S2_554_differentially_expressed_genes_between_DOX_and_CTR_D0_in_A673pTERshEWS_FLI1_model_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
CTB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68199
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161170,GSE161268_0_v_3_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.168381
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9896
Ventral tegmental area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04468
CAPECITABINE	DGIdb Drug Targets 2026	1.0	1.9248
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02666
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A44A-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93331
PR, GR	MotifMap Predicted Transcription Factor Targets	1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A60K-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDHL8	DepMap CRISPR Gene Dependency	1.0	4.19606
ADAM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14073
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	6.64365
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
2313287	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81154
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNU1327	DepMap CRISPR Gene Dependency	1.0	8.1515
SFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78699
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5682
GSE176389_0_v_1_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6010-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01054
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65323
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50079
PMC10985171-Table_1.xlsx-Table_S3-Table_S3_IPF_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73123
small intestine	GTEx Tissue Gene Expression Profiles	1.0	1.63383
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9833
RNASEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95822
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3214
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225647
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-2.09918
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.013
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.20273
SYPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73464
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6744561-41467_2019_12125_MOESM8_ESM.xlsx-SEs_in_MCF10DCIS-TCF7_cells-Enhancer_to_gene_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
PRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94588
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09478
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6766
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61347
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17168
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16228
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09824
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
FTC133	DepMap CRISPR Gene Dependency	1.0	3.85838
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12143
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35348
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TM2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5064
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91323
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44293
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0873
hsa-miR-374c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PTPMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35432
Perturb_16534_KO_Cdk8/Cdk19_SRP351257	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25266
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90262
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
AHR	ChEA Transcription Factor Targets	1.0	null
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56125
TSPAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06693
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85057
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.08891
Astroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58987
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.04948
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ADRA2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34595
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
hsa-miR-567	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9768
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38289
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52W-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32564
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03439
A1207	CCLE Cell Line Gene Expression Profiles	-1.0	-2.32273
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54682
GSE98964_0_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67255
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52906
HOSE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
NCIH684	CCLE Cell Line Gene Expression Profiles	1.0	1.8406
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00524
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849133
NCIH1568	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01478
Sarcoma_SARC_TCGA-HB-A2OT-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00124
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78727
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.593212
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	3.77901
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40899
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
PSN1	DepMap CRISPR Gene Dependency	1.0	4.56836
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4874-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57322
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9373
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00235
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20565
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91648
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78411
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
CAL-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SK-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1355	CCLE Cell Line Gene Expression Profiles	1.0	2.04918
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01786
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69351
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36738
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.982985
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.372587
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21415
SNU245	CCLE Cell Line Gene Expression Profiles	1.0	1.43149
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Table_S5A_Upregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8626
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.14074
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09561
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91138
SR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior parietal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27339
K029AX	DepMap CRISPR Gene Dependency	1.0	3.25705
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09741
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.67288
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ANP32D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11712
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24559
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23301
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1178
Brain Lower Grade Glioma_LGG_TCGA-DB-A64S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
YD15	DepMap CRISPR Gene Dependency	1.0	2.36223
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S23_LF_C1_24h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35561
PC14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62694
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66522
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838718
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03294
individuals	GeneRIF Biological Term Annotations	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0715
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91784
RB1_KD_GSE50532_654_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04038
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04038
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Adolescent Idiopathic Scoliosis	DisGeNET Gene-Disease Associations	1.0	null
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00067
STAT3	ENCODE Transcription Factor Targets	1.0	null
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0711
Captopril_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0254826
NCIH2023	CCLE Cell Line Gene CNV Profiles	1.0	1.72374
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49151
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW403	DepMap CRISPR Gene Dependency	1.0	4.25967
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42833
LN464	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49342
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63249
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54876
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.27574
HUG1N	CCLE Cell Line Gene Expression Profiles	1.0	1.46957
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14997
SMAD3-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87555
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5011
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SP4_SP4	Rummagene Transcription Factor Associations 2026	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44618
Uterine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
KYSE-520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN28	DepMap CRISPR Gene Dependency	1.0	3.26256
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37549
receptor activity	GO Molecular Function Annotations 2015	1.0	null
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38683
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57568
Lung squamous cell carcinoma_LUSC_TCGA-98-A538-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09737
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04937
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03256
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9499
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51843
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.653584
MICALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59955
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MKNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
SIN3A	ENCODE Transcription Factor Targets	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE174383_2_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3705
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10783
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Brain Lower Grade Glioma_LGG_TCGA-DU-7011-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08645
A_CA_04_2009_7dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.85976
SF172	CCLE Cell Line Gene CNV Profiles	1.0	2.16121
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
G protein-coupled receptor activity	GO Molecular Function Annotations 2023	1.0	null
DKMG	CCLE Cell Line Gene Expression Profiles	1.0	2.65581
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100295_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.20969
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04066
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040433
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39807
Androgen-Insensitivity Syndrome	DisGeNET Gene-Disease Associations	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02684
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.866239
GSE132948,GSE132949_4_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE198165,GSE198166_9_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A6M7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.92725
PMC11551338-pnas.2411189121.sd01.xlsx-VDR-Unnamed_0_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95107
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39053
biological regulation	GO Biological Process Annotations 2015	1.0	null
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74017
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17168
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1467
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876979
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1001
GSE218060_5_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GAMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58247
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962118
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CYBC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95826
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4649
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46837
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96754
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
TMEM231	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42097
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74601
P2RX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83389
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-655	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20624
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C80	DepMap CRISPR Gene Dependency	1.0	2.3973
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	1.67525
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.4301
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.948349
PMC10863010-media-2.xlsx-ST18-Unnamed_4_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-548k	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07497
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9379
MKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039233
decreased heart weight	IMPC Knockout Mouse Phenotypes	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-1299	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SYO1	DepMap CRISPR Gene Dependency	1.0	2.85741
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00036
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08942
JHH2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46261
CEBPB	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.06907
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58891
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD3	ChEA Transcription Factor Targets	1.0	null
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00187
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3554
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36789
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
KP3	DepMap CRISPR Gene Dependency	1.0	4.48544
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979137
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7929
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32068
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38881
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14903
Perturb_7998_KO_Scrib/Taz/Yap1_SRP265287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.75748
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45512
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.4
BCL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92327
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10783
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.03619
hsa-miR-561	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
AHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73785
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43746
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09833
STYX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78211
TBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94226
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.781177
ZFP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48938
Adrenocortical carcinoma_ACC_TCGA-OR-A5JW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.857006
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37405
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00466
decreased total retina thickness	MGI Mouse Phenotype Associations 2023	1.0	null
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45431
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPCR, family 2, secretin-like	InterPro Predicted Protein Domain Annotations	1.0	null
HNF1A-26855178-CACO2-HUMAN-COLON-ADENOCARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.11009
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_6_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260267
CCFSTTG1	DepMap CRISPR Gene Dependency	1.0	2.25014
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35091
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46616
SLC18A3_KD_GDS4325_618_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29615
RBM15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19351
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JW-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13051
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929074
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU478	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78084
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17124
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SF295	CCLE Cell Line Gene CNV Profiles	1.0	1.41908
GSE179880_10_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31859
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71292
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08942
ATM_knockout_75_GSE23116	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.56916
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74251
CAPAN-1	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08645
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02098
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68429
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49307
Acute Myeloid Leukemia_LAML_TCGA-AB-2918-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3256
GSE218060_5_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TWF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50391
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TI-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fostamatinib (disodium hexahydrate)_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0117863
RRP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58443
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0391
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988955
BCOR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
signal transduction	GO Biological Process Annotations 2015	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF	ENCODE Transcription Factor Targets	1.0	null
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6701
SNU1033	CCLE Cell Line Gene Expression Profiles	1.0	1.41114
CADOES1	CCLE Cell Line Gene CNV Profiles	1.0	1.46084
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46493
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23861
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0471
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
interstinal hyperperistalsis	MGI Mouse Phenotype Associations 2023	1.0	null
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63136
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1092	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23227
OVCAR8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81455
Perturb_16302_KO_Esr1_SRP115139	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.6575
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95933
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51038
GAREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7601
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31537
ZNF805	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01826
NCIH1755	DepMap CRISPR Gene Dependency	1.0	3.90919
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04543
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95519
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92334
RHOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88876
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945614
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4515	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54551
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4676
RERFLCMS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96104
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17659
pancreas	HPA Tissue Protein Expression Profiles	1.0	1.14074
CAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89167
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22813
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56486
ATP1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96586
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02053
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04631
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
AR	ChEA Transcription Factor Targets	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8278
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
Perturb_1665_KO_Rigi/Mda5_SRP119759	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19977
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54472
ALDH18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70625
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50893
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838718
MERO82	DepMap CRISPR Gene Dependency	1.0	5.32978
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0504
Myeloproliferative neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
hsa-miR-371-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46622
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7997_KO_Scrib_SRP265287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.38789
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27207
PPARG	ChEA Transcription Factor Targets	1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00843
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00475
Sneddon syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01379
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.684166
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88454
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836559
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12086
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40553
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40652
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55364
GATA1	ChEA Transcription Factor Targets	1.0	null
Supramammillary nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0085
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61273
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Small_Intestine-mature enterocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.414587
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82165
ZRANB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28949
GBX2-23144817-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96756
Lung squamous cell carcinoma_LUSC_TCGA-56-8622-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.65108
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.938
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46308
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SPI1	ENCODE Transcription Factor Targets	1.0	null
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6791
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PKIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83658
exon-exon junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.134
OTX	MotifMap Predicted Transcription Factor Targets	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0684
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47517
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46491
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
perimammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13507
SETD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35411
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10092
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25624
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93898
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5937
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04899
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08538
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
G protein-coupled receptor activity	GO Molecular Function Annotations 2025	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8089-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JL1	CCLE Cell Line Gene Expression Profiles	1.0	2.13549
PNPLA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48006
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45477
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5177
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60944
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4961-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12984
Childhood Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ADCY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65374
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49183
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8111
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24479
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A9QD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71812
hsa-miR-1297	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46388
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2381
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22398
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76095
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.4382
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NB17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3425-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77852
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66522
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-01A-21R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7231-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3288
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
10min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75657
C22orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7588
GPSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47739
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981379
Lung squamous cell carcinoma_LUSC_TCGA-33-4566-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836559
hsa-miR-4324	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70456
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10988
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKMEL2	CCLE Cell Line Gene CNV Profiles	1.0	1.57024
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34714
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3985
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61571
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58553
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47546
kidney	HPA Tissue Protein Expression Profiles	-1.0	-0.857006
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20156
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7465
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29221
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8468
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.20513
HMOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glomus tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
abnormal eye anterior chamber depth	MGI Mouse Phenotype Associations 2023	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7655
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4810-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SLC39A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40268
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23122
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.1075
KIF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96801
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.09915
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66102
NCIH2052	CCLE Cell Line Gene Expression Profiles	1.0	1.45881
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69579
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67755
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
ENSG00000230707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36834
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.590722
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55735
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38994
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	1.57145
Lung squamous cell carcinoma_LUSC_TCGA-66-2792-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28773
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43658
INKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84452
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24626
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42201
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.857006
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165874
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15995
Lung squamous cell carcinoma_LUSC_TCGA-60-2703-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NO-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LNZ308	CCLE Cell Line Gene Expression Profiles	1.0	1.60843
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0YX-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09091
HOXC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81565
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0703
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30762
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07431
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32074
A_CA_04_2009_4dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.09428
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18913
increased cornea thickness	IMPC Knockout Mouse Phenotypes	1.0	null
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18063
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0485
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SF126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58502
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.281
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66574
HEC6	DepMap CRISPR Gene Dependency	1.0	4.57412
RNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95653
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6816
PMC10863010-media-2.xlsx-ST18-Unnamed_3_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7352
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66516
SFXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
UBE2Q1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55295
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49109
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47685
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
SW1783	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47742
SRF	ENCODE Transcription Factor Targets	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34494
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40548
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050504
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29124
FUCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06291
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13417
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46582
HCT116	DepMap CRISPR Gene Dependency	1.0	3.50069
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84766
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99639
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01454
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2358
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77313
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7833
NALM16	DepMap CRISPR Gene Dependency	1.0	3.02658
Lung squamous cell carcinoma_LUSC_TCGA-66-2787-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32116
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02098
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28329
ITGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62082
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3401
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARID1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92579
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08255
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91282
Dendritic lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
GSE116299_6_v_5_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01396
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2328
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15838
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09833
SENP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2447
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
SIRT3_KO_GDS4817_416_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14385
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93877
SARS-CoV NSP16_Day2_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.7051
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.032721
PMC9314667-Table_1.xlsx-Regulons-IRF7_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
HS695T	DepMap CRISPR Gene Dependency	1.0	3.53563
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93107
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07517
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29637
Osteogenesis imperfecta type 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.742
496100296_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.40557
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1442
SPI1	ChEA Transcription Factor Targets	1.0	null
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501182
Perturb_3416_KO_Cdx2/Apc_SRP093647	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-3691-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2981
membrane	GO Cellular Component Annotations 2015	1.0	null
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21769
PMC8582123-13073_2021_996_MOESM4_ESM.xlsx-SATB1-HIT_SATB1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14255
PMC7788918-13058_2020_1379_MOESM2_ESM.xlsx-S9-S9_limma_voom_differentially_expressed_genes_ESR1_depleted_recurrences_vs_matched_primaries_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Fibrogenesis imperfecta ossium	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.46
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17168
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36622
hypertension	GWASdb SNP-Disease Associations	1.0	0.755004
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.9039
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53703
CAL-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U2-type spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20983
hsa-miR-592	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43524
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956791
SARS-CoV MA15_Day1-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45053
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Agranular insular area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06333
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PECAPJ49	DepMap CRISPR Gene Dependency	1.0	2.45927
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80843
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05696
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38093
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25522
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22189
NCI-H747	COSMIC Cell Line Gene Mutation Profiles	1.0	null
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.857006
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.44491
CFPAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMRC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42335
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.59382
Cysticercus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20466
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73919
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99222
hsa-miR-26b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15767
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28096
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040269
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929917
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.069709
hsa-miR-4257	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882392
SKHEP1	DepMap CRISPR Gene Dependency	1.0	2.83297
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.61555
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55022
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18781
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8664
GSE152432_1_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79706
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03115
YY1	ChEA Transcription Factor Targets	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88534
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3443
Brain Lower Grade Glioma_LGG_TCGA-P5-A731-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.60163
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33294
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.942124
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98631
Dorsal nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45971
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9421
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2077
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35091
Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03967
uterus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
MYC	ChEA Transcription Factor Targets	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830175
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74077
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36185
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2008_KO_Arid1a_SRP182831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.62791
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.07131
cerebellum	HPA Tissue Protein Expression Profiles	1.0	1.14074
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1106
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62443
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.511
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51809
GSE65617_2_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
CDC42EP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21566
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE150	DepMap CRISPR Gene Dependency	1.0	2.61213
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47021
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HEC1A	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40883
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
hsa-miR-4669	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946777
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0245
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03115
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7464
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94065
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04021
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5848
MG63	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0789
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08597
HS281T	CCLE Cell Line Gene Expression Profiles	1.0	3.3863
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12926
PMC11551338-pnas.2411189121.sd01.xlsx-PXR-Unnamed_0_NR1I2	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A3Y1-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34596
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13507
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mantle zone of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13507
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68554
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0286
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.857006
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
decreased heart weight	MGI Mouse Phenotype Associations 2023	1.0	null
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10985
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37748
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16612_KO_Mfn2_SRP356670	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.3016
NUCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90326
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57535
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39696
GSE143790_0_v_1_bcl9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29027
EPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9123
RNF2	ENCODE Transcription Factor Targets	1.0	null
JURLMK1	DepMap CRISPR Gene Dependency	1.0	2.11445
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9935
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03431
furan	CTD Gene-Chemical Interactions	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981379
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.9778
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14711
CDK9_druginhibition_183_GSE48258	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.089856
Adult Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945614
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851547
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.4651
MUTYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57891
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNUC5	DepMap CRISPR Gene Dependency	1.0	6.71912
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84691
SF295	CCLE Cell Line Gene Expression Profiles	1.0	1.87449
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
GSE220520_5_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.14074
hsa-miR-297	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
OELE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15484
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52296
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RMG-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-4646-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Childhood T-cell acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32277
TAL1	ENCODE Transcription Factor Targets	1.0	null
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.41432
H2BC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53031
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3063
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05932
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	1.36939
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57688
DNAJC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37844
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38548
EP300	ENCODE Transcription Factor Targets	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10834
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45267
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE246983_1_v_0_cdk12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57471
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14274
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2242
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85026
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small intestine	HPA Tissue Gene Expression Profiles	1.0	1.18792
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LASV_FML29_8hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.78355
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6115
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1809
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28423
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34663
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3605
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58716
ARNT	ChEA Transcription Factor Targets	1.0	null
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11083
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EW-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14693
FYTTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66816
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-520h	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Perturb_10320_KO_HDAC1/HDAC2_SRP255858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.5107
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07299
RC-K8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36837
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21032
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81933
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95286
DDX53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27041
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.25415
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8089
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.57179
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K27me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70764
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47984
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59963
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26804
healthy	GeneRIF Biological Term Annotations	1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6542
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal eye anterior chamber depth	IMPC Knockout Mouse Phenotypes	1.0	null
Perturb_14447_KO_Jmjd3_SRP356900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.39558
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09655
GSE104022_3_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56073
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849133
LRRC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52963
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RL952	CCLE Cell Line Gene Expression Profiles	1.0	1.96336
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33622
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929917
ATF1	ENCODE Transcription Factor Targets	1.0	null
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15382
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6793
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06246
HPAFII	DepMap CRISPR Gene Dependency	1.0	2.14376
Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43939
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8791
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04551
GBX2	ChEA Transcription Factor Targets	1.0	null
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46065
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GMP reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41667
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68629
ZNF248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61044
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.857006
hsa-miR-3607-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.083169
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59356
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7607
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17076
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43746
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02078
NFYB	ENCODE Transcription Factor Targets	1.0	null
DRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72037
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27248
HCC2998	DepMap CRISPR Gene Dependency	1.0	6.45908
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9875
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17359
Small_Intestine-immature enterocyte	Tabula Sapiens Gene-Cell Associations	1.0	4.53254
hsa-miR-599	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	1.45827
SMAD4	ChEA Transcription Factor Targets	1.0	null
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4286
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828079
NCIH1693	DepMap CRISPR Gene Dependency	1.0	2.79681
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22915
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19318
PANK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99661
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JM1	CCLE Cell Line Gene Expression Profiles	1.0	1.51979
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NB(TU)1-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946777
KRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87305
ELK1	ENCODE Transcription Factor Targets	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
duodenum	HPA Tissue Gene Expression Profiles	1.0	1.21764
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7209
hsa-miR-7	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SET2	DepMap CRISPR Gene Dependency	1.0	7.36803
SMSCTR	DepMap CRISPR Gene Dependency	1.0	3.03507
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909879
0min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26898
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1200	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GPS motif	InterPro Predicted Protein Domain Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7638-01B-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	1.53676
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96123
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6169
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876979
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07121
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.55684
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9631
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04066
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35399
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22914
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8532
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11961
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18765
NCI-H720	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02806
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49918
Perturb_7999_KO_Wwtr1/Yap1_SRP265287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.23309
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC9374162-mmc4.xls-KD_gene_list_heatmap_235_genes-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MOLT13	CCLE Cell Line Gene Expression Profiles	1.0	1.76977
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39486
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4143
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76804
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840324
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4433	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981379
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890972
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81237
AMMECR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8697
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IST-SL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C3A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHOS4	CCLE Cell Line Gene Expression Profiles	-1.0	-3.36375
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89805
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70467
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46972
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02684
PEO1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00689
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.866713
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838718
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RS411	CCLE Cell Line Gene Expression Profiles	1.0	1.57898
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A545-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_3907_KO_DUSP6_SRP229874	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
hsa-miR-4428	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26287
SUDHL4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86557
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7969
ovary	HPA Tissue Protein Expression Profiles	-1.0	-2.57656
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859375
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26578
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-IRF1-HIT_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
KIFBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42997
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2137
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3402
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
nucleus of Barrington	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18712
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.857621
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71063
496100297_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.1615
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52025
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PACSIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76371
Lung adenocarcinoma_LUAD_TCGA-95-7039-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840324
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30398
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93X-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70755
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H661	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43056
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05475
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.76703
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18946
NMCG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83663
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_8-Supplementary_Table_8_ETV6-repressed_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCA4	ChEA Transcription Factor Targets	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28722
G3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.8408
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00796
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15902
GSE174383_2_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46424
Nerve sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
Perturb_17320_KO_miR106b~25_ERP121195	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.0814
Gestational choriocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
GPCR, family 2-like	InterPro Predicted Protein Domain Annotations	1.0	null
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19986
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01134
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41156
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929917
NOVA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
myeloproliferative	GeneRIF Biological Term Annotations	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76251
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93588
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65147
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28472
LHX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03187
AGMAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66048
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PA-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.14074
ZNF728	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44209
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6021-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47601
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.764
abnormal retina outer nuclear layer morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56982
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	2.54305
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8501
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7	DepMap CRISPR Gene Dependency	1.0	3.39635
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08453
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14261
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5855-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cestode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62131
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9768
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09009
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26018
HS281T	CCLE Cell Line Gene CNV Profiles	1.0	2.1389
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64187
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7863452-12920_2021_883_MOESM5_ESM.xls-SRG_13_GE2-HCC_vs_17NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV MA15_Day1_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.26597
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75215
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HEKTE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A2PC-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF	MotifMap Predicted Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4736-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34081
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
EI24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66064
v91	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14617
hsa-miR-26a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
r2c	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93107
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7919-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oculomotor nucleus, Edinger-Westphal subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46097
SW1710	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08068
SW1116	CCLE Cell Line Gene Expression Profiles	1.0	1.3914
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
SKMEL28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5936
Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.115842
RELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61542
MTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60048
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56652
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01661
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-0.974304
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840324
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44772
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
697	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PNMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69298
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08369
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866696
HNF4A	ChEA Transcription Factor Targets	1.0	null
CNTNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44786
NCIH1048	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75152
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4306	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SARS-CoV MA15_Day2-C57BL6_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.02633
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24216
DDX50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68454
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.85703
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55636
MIR34_OE_GDS2755_645_human_HCT116 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15136
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.857006
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.989554
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
neoplasms	GeneRIF Biological Term Annotations	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PRKAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94127
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83122
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4919
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20728
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890972
TEAD4	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26365
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08369
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929917
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93633
duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.367129
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	2.15265
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35582
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54847
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83727
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-597	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43729
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01453
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956791
LAMA84	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88984
DPY19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70863
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50348
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Small_Intestine-intestinal crypt stem cell of small intestine	Tabula Sapiens Gene-Cell Associations	1.0	0.607918
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548ag	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
AHR-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04468
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41018
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830175
CBX2	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.632
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52833
TEAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8169
DIFI	DepMap CRISPR Gene Dependency	1.0	2.39233
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89637
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
PPP2R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93935
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13781
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Posterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.14179
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931839
Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
slow postnatal weight gain	MGI Mouse Phenotype Associations 2023	1.0	null
MDA-MB-175-VII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28457
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16195
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DKMG	CCLE Cell Line Gene CNV Profiles	1.0	2.62712
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0711
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45037
Cytoplasmic ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050587
RIGI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11081
WERIRB1	DepMap CRISPR Gene Dependency	1.0	5.08679
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74806
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21415
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27769
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1573	CCLE Cell Line Gene Expression Profiles	1.0	1.7601
MXI1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased cornea thickness	MGI Mouse Phenotype Associations 2023	1.0	null
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53175
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1573	CCLE Cell Line Gene CNV Profiles	1.0	1.91351
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BLTP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45881
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	1.47513
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.756806
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.063
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19858
hsa-miR-186	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38727
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06729
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00793
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90719
MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215534
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04774
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89328
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03194
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HTT	ChEA Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36951
NCIH226	DepMap CRISPR Gene Dependency	1.0	3.66336
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21949
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47288
trkfused	GeneRIF Biological Term Annotations	1.0	null
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MA-10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
VCB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11481
t70-white-adipose_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	1.69639
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
USP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92254
GSE200320_1_v_0_mfge8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0039
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.6509
placenta	HPA Tissue Protein Expression Profiles	1.0	1.14074
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
PMC12178384-mmc6.xlsx-Sheet1-Supp_Table_4_Differential_expression_analysis_of_CIC-rearranged_sarcomas_vs_CIC-rearranged-like_sarcomas_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4762-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23018
OE19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inframe	GeneRIF Biological Term Annotations	1.0	null
AOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04487
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74971
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00833
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2828-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1738_KO_Arid2_SRP300754	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.3809
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945614
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82264
DSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6551
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28722
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78658
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.972993
NCIH2023	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
METTL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.162
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0717
SLR20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65568
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09144
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
EOL-1-CELL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	2.10258
HEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08017
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormal retina outer nuclear layer morphology	IMPC Knockout Mouse Phenotypes	1.0	null
RL952	CCLE Cell Line Gene CNV Profiles	1.0	2.89542
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
LMO2	ChEA Transcription Factor Targets	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35773
NCIH1618	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46235
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.0263
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2618
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	1.64123
PMC12178384-mmc5.xlsx-Sheet1-Supp_Table_3_Differential_expression_analysis_of_CIC-rearranged_sarcomas_vs_Ewing_sarcomas_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
decreased total retina thickness	IMPC Knockout Mouse Phenotypes	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ectopic Cushing syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
PMC12178384-mmc4.xlsx-Sheet1-Supp_Table_2_Differential_expression_analysis_of_CIC-rearranged_sarcomas_vs_BCOR-rearranged_sarcomas_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03008
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV434	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53536
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29388
Hydrocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860485
DANG	CCLE Cell Line Gene CNV Profiles	1.0	1.3373
Uterine luminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GJ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904436
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.05201
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56299
INKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26083
EFHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62874
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18913
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50634
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050587
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.532
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27188
liver	GTEx Tissue Gene Expression Profiles	1.0	1.12035
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.1385
liver	HPA Tissue Gene Expression Profiles	1.0	0.930099
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89849
Translation preinitiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93155
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18913
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5737-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.030403
PMC12304111-41598_2025_13196_MOESM5_ESM.xlsx-Sheet_1-Table_S4_DEGs_Log2FC_1_and_p_adj_0_05_in_pancreatic_cancer_with_high_versus_low_OVOL1_expression_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
ORMDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43218
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cerebral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54088
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23616
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR	Rummagene Transcription Factor Associations 2026	1.0	null
P2RX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
AZ521	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66175
colon	GTEx Tissue Gene Expression Profiles	1.0	0.843973
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
NCIH508	CCLE Cell Line Gene Expression Profiles	1.0	1.35762
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39658
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76647
ZNF197	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22453
hsa-miR-548ai	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
LN319	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35879
hsa-miR-412	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
POU3F2	ChEA Transcription Factor Targets	1.0	null
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.76399
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE196540,GSE196542_4_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A264-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27116
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23855
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81535
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.399
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14683
MOG-G-CCM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5748
IRF1	ENCODE Transcription Factor Targets	1.0	null
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1666_KO_Rigi_SRP119759	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.62694
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.24793
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99951
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0663
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.01918
M040416	DepMap CRISPR Gene Dependency	1.0	2.34729
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08489
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42898
ZNF76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99499
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13642
RCOR1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27116
embryo	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
DESI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95306
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74215
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94806
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82078
Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
YAP1	ChEA Transcription Factor Targets	1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH10TC	DepMap CRISPR Gene Dependency	1.0	2.33494
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16891
disease	GWASdb SNP-Disease Associations	1.0	0.027627
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17322
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6561
CUX1	ChEA Transcription Factor Targets	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23535
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78078
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15411
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19856
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57965
Lung squamous cell carcinoma_LUSC_TCGA-77-7463-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2945
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF709	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50795
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0315
ARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74575
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5642
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBX8	ENCODE Transcription Factor Targets	1.0	null
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37473
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01442
KD	DepMap CRISPR Gene Dependency	1.0	4.4697
DBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59702
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.65555
MGAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5328
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30722
DMRTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34985
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35704
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW954	DepMap CRISPR Gene Dependency	1.0	4.06846
SNAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20115
NCC021	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH82	CCLE Cell Line Gene Expression Profiles	1.0	1.76966
NCIH82	CCLE Cell Line Gene CNV Profiles	1.0	2.17033
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08891
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030446
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50893
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36211
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78154
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7796
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29119
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93004
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.918726
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09226
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.153
IKBKB_Constitutional activation_GDS4119_621_mouse_Prostate epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-520g	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6397
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
APOBEC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2701
SMARCA4-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CITED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57055
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10537
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35884
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02201
hsa-miR-3915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.504316
hsa-miR-185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22008
Small_Intestine-intestinal crypt stem cell	Tabula Sapiens Gene-Cell Associations	1.0	0.124591
SG231	DepMap CRISPR Gene Dependency	1.0	3.55451
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62732
hsa-miR-3121-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
hsa-miR-4644	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890972
Thyroid Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.3853
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.69719
GSE152032_3_v_2_s1pr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.17731
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8921
PATU8902	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58511
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47081
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47641
Acute Myeloid Leukemia_LAML_TCGA-AB-2877-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HTT-18923047-STHdh-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3 histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1845
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15236
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.5235
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98051
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25368
protein binding	GO Molecular Function Annotations 2015	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81802
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74924
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35243
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2733
Perturb_4484_OE_Msi2_SRP067535	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.80256
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.46926
UBE2O	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8098
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3648
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96876
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
Odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3743
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22864
RBM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78905
NCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70518
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929917
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18781
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4218
GSE221101_1_v_0_hopx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40582