association	dataset	threshold value	standardized value
Perturb_7384_KO|KD_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CD47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32753
abnormality of finger	HPO Gene-Disease Associations	1.0	null
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12045
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886862
Ichthyosis Congenita	DisGeNET Gene-Disease Associations	1.0	null
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3314
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7225
synthase	GeneRIF Biological Term Annotations	1.0	null
scaly skin	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6836
positive regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital nonbullous ichthyosiform erythroderma	ClinVar Gene-Phenotype Associations 2025	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
Perturb_8131_KD_EIF2S1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.3267
PMC2742785__F8	PFOCR Pathway Figure Associations 2023	1.0	null
Bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67023
Perturb_6233_KO_Ugt8_SRP073495	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.73386
prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065591
BRD-K65440031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34672
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21551
BRD-K74779337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22233
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7542
mutated	GeneRIF Biological Term Annotations	1.0	null
Photosensitive trichothiodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.825
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9942993-pone.0281645.s002.xlsx-non-AR_as_all_as_gained-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19217
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18603
BRD-K55965167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29085
coronary disease; coronary heart disease; myocardial infarction	GAD Gene-Disease Associations	1.0	null
Perturb_11432_OE_OC2_SRP122890	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.60443
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.36929
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
esophagus	HPA Tissue Gene Expression Profiles	1.0	0.964849
Brachial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.399
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.426693
TGM1	Pathway Commons Protein-Protein Interactions	1.0	null
c-MYC_KD_GDS2526_112_human_MCF-7 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-3921	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059379
Perturb_6724_KD_PAF1_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.85278
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29763
Perturb_13998_OE_MIR1271_SRP256886	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.0587
selfimproving	GeneRIF Biological Term Annotations	1.0	null
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0834
mantle zone of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84004
SW900	CCLE Cell Line Gene CNV Profiles	1.0	1.53151
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68303
lipid modification	GO Biological Process Annotations 2023	1.0	null
BRD-K77733130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.103
GSE160817_3_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36063519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0254
leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496483
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4219
recessive	GeneRIF Biological Term Annotations	1.0	null
SKN	DepMap CRISPR Gene Dependency	1.0	2.65744
Paralysed	DisGeNET Gene-Phenotype Associations	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ichthyosiform	GeneRIF Biological Term Annotations	1.0	null
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37258
Hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28107
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5002
Chanarin-Dorfman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.694
BRD-K64577478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0689
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056941
Subiculum, dorsal part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54761
BRD-K26074237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44676
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7685
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07485
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9328
PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824338
tests	GeneRIF Biological Term Annotations	1.0	null
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1543
BRD-K38111331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68599
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
BRD-K61973443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2186
Cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.259
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.07648
BRD-K21232462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6907
BRD-K87205390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2244
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.7778
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10267
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6929
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79587
BRD-K72842159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31014
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06976
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56881
abnormal fluid regulation	MPO Gene-Phenotype Associations	1.0	null
SKHEP1	CCLE Cell Line Gene CNV Profiles	1.0	1.41487
SALE	CCLE Cell Line Gene Expression Profiles	1.0	1.47659
BRD-K21660570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24666
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.58604
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11511846-42003_2024_7078_MOESM3_ESM.xlsx-ST18-Unnamed_19_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.181
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10304
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50836
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2113
BRD-K44401972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3233
496100567_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70368
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1871
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2699
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_11377_KD_TMEFF2_SRP153936	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.30172
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.981018
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
arachidonate 12(S)-lipoxygenase activity	GO Molecular Function Annotations 2023	1.0	null
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7994
Autosomal recessive congenital ichthyosis 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
GSE239784_1_v_0_sat1_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16266
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03625
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43949
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94884
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19684
ETF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32343
Perturb_15147_KD_EHF_SRP081174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.83333
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02856
Subiculum, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20007
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852489
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC9825391-41467_2022_35592_MOESM4_ESM.xlsx-MAF_Targeted_Seq_mutations-Muation_Annotation_File_MAF_used_in_Figures_1b-e_3a-b_Supplementary_Figures_2d_2f_2g_and_4a_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39995
long-chain fatty acid biosynthetic process	GO Biological Process Annotations 2025	1.0	null
HT-1080 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
BRD-K74056311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21393
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32862
intermediate stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07546
REEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93584
allowed	GeneRIF Biological Term Annotations	1.0	null
SOX11	ChEA Transcription Factor Targets	1.0	null
positive regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
positive regulation of MAPK cascade	GO Biological Process Annotations 2025	1.0	null
Perturb_3646_KO_HDAC1_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.54886
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862309
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13436
Perturb_15718_OE|KD_Ctcf|Smarca5_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.9638
Pachyonychia congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
Perturb_11387_OE_OC2_SRP122890	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.33769
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08145
ZNF621	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23681
BRD-K13336710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05165
BRD-K22508525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12848
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938769
GATA4_KO_GDS3486_483_mouse_jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ES3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bergapten	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53109
BRD-K79734831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05979
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01326
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CHRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47468
heterozygous	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12580_OE_STK32B_SRP261296	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.86352
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.874373
BRD-K09583061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16917
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961037
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86155
EHMT2_KD_GDS4800_315_human_MDA-MB231	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Epidermal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
BRD-K98793503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33996
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24051
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27097
Body Mass Index	dbGAP Gene-Trait Associations	1.0	0.189972
SUZ12	ChEA Transcription Factor Targets	1.0	null
Chromophobe Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.161
Cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.708
dry skin	HPO Gene-Disease Associations	1.0	null
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4806
BRD-K43136464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07812
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	145.182
CARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83777
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-79-5596-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r5 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61241
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	1.0	0.978808
Fatty Liver	CTD Gene-Disease Associations	1.0	1.23074
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epidermal cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hxali	GeneRIF Biological Term Annotations	1.0	null
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.93004
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24271
NOS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60738
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26115
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967658
protein modification process	GO Biological Process Annotations 2023	1.0	null
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12553
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845573
BRD-K89260735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4479
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35786
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06751
BRD-K61383885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28133
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03101
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
positive regulation of MAPK cascade	GO Biological Process Annotations 2023	1.0	null
hxa3	GeneRIF Biological Term Annotations	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.6955
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51209
body composition	GAD Gene-Disease Associations	1.0	null
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.969555
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6561-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16904
BRD-K74694052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1558
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
BRD-K68424387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24899
BRD-K95218317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08336
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17139
octopamine-6491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
structural	GeneRIF Biological Term Annotations	1.0	null
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15517
multicellular organismal water homeostasis	GO Biological Process Annotations 2015	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
scandinavia	GeneRIF Biological Term Annotations	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12738
8305C	DepMap CRISPR Gene Dependency	1.0	2.77381
HNRNPUL1_02_109	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.58496
icSARS CoV_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.59437
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52606
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08537
abnormality of the hand	HPO Gene-Disease Associations	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.67853
BRD-K83090041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72338
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13563
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21561
BRD-K28429328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35073
BRD-K34519170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15767
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25326
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5905-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64953645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02137
BRD-K12909905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4463
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.67958
L1236	CCLE Cell Line Gene Expression Profiles	1.0	1.64222
central subpallium (classic basal ganglia)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11689
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38761
amide biosynthetic process	GO Biological Process Annotations 2025	1.0	null
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01719
Perturb_14319_KD_YAP_SRP251526	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.6833
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
L-428	GDSC Cell Line Gene Expression Profiles	1.0	1.81441
small molecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3263
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7411-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.839
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17785
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18502
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
BRD-K86073842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46889
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32492
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57201
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45835
BRD-K97949309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49415
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02993
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.06897
hepoxilin metabolic process	GO Biological Process Annotations 2025	1.0	null
BPHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3123
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Retrosplenial area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.107
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63857
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1975
BRD-K61363662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13779
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	GO Molecular Function Annotations 2023	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14563
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05459
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	1.48659
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.96282
Epidermolysis bullosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840375
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.894075
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836259
CRCGN016_MCF10A.WT.HP_24H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14045
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72907
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10164
MYC	ENCODE Transcription Factor Targets	1.0	null
PMC4515859__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85606
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
MET_knockout_263_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.17287
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36675
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44178
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	GO Molecular Function Annotations 2025	1.0	null
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.295739
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25071
BRD-K50721666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2137
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22161
PRKACG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28974
BRD-K60030763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95784
NFYB	ENCODE Transcription Factor Targets	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.576015
Perturb_8085_KD_DAZAP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.58244
BRD-K11442063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12106
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.90326
shiny skin	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K45010872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12896
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43415
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21853
BRD-K81144230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08988
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31236
BRD-K45941986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60157
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TP53_01_31	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.21809
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51858
DSH1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59272
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863456
BRD-K51641263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06149
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4776-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart disease	GWASdb SNP-Disease Associations	1.0	0.697052
BRD-K12119989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18605
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824347
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72935
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3132
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44694
THBS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8946
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42982
BRD-K06367273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36166
BRD-K28319429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05785
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045644
BRD-K92904754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36876
BRD-K55237592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03743
all	HPO Gene-Disease Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98552
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_17301_OE_Id4_SRP097179	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.20053
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61444
BRD-K19142902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01759
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4217
Perturb_15506_KD_MED1_SRP179971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K92913380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20846
BRD-K60744874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2076
PMC12808183-41598_2025_31780_MOESM6_ESM.pdf-2-ATF3_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11349
features	GeneRIF Biological Term Annotations	1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4C5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497602
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873724
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50325
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58864
BRD-K86039224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07851
fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90325960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42718
BRD-K28034484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46029
mode of inheritance	HPO Gene-Disease Associations	1.0	null
BRD-K54100199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47058
hyperkeratosis	HPO Gene-Disease Associations	1.0	null
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05302
Fe2+	HMDB Metabolites of Enzymes	1.0	null
BRD-K73792260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44885
PMC9314343-41467_2022_31892_MOESM8_ESM.xlsx-Fig7e-CTCF_in_promoter_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23153
enzyme	GeneRIF Biological Term Annotations	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06958718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00257
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27509
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
Ectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
dioxygenase activity	GO Molecular Function Annotations 2015	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10839
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4153-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58019
abnormal lipid level	MPO Gene-Phenotype Associations	1.0	null
PMC12074931-Table_1.xlsx-Sheet1-NFE2L2_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
TGM2_KD_GSE23702_716_human_NB4 cells, 72h ATRA-induced differentiation	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54483
Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897768
15930337-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16028
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1112
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04395
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.90629
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48034
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28707
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237531
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.726891
TP63_NULL MUTATION_GDS1434_308_mouse_Skin at embryonic age E18.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
PMC10861538-41467_2024_45669_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_DEGs_upon_KD_of_EVT_TFs_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal recessive congenital ichthyosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
Perturb_15717_OE_Ctcf_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9882
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54385
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.985956
BRD-K53893978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00617
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069184
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
BRD-K75539052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38311
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.64589
BRD-K54939987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90649
Perturb_13094_KD_Gcn5_SRP057021	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.8005
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00907
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09159
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4093
cases	GeneRIF Biological Term Annotations	1.0	null
abnormality of skin morphology	HPO Gene-Disease Associations	1.0	null
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57476
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02299
PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3	Rummagene Transcription Factor Associations 2026	1.0	null
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57997
BRD-K28952606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09719
BRD-A71933035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26473
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
roles	GeneRIF Biological Term Annotations	1.0	null
Field CA1, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15594
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89408
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00804
collodion	GeneRIF Biological Term Annotations	1.0	null
PMC4773428-ncomms10751-s5.xlsx-S_Table_4-Supplementary_Data_4_RUNX1_responsive_genes_in_the_presence_and_absence_of_estradiol_E2_in_MCF7_cells_FC_1_5_p_0_05_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22928
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33783
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
sweat gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.754527
lossoffunction	GeneRIF Biological Term Annotations	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55896279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39308
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
pruritus	HPO Gene-Disease Associations	1.0	null
arachidonic acid metabolic process	GO Biological Process Annotations 2023	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54469
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
BRD-K72687327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04012
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13259
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.37701
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
aplasia/hypoplasia involving the skeleton	HPO Gene-Disease Associations	1.0	null
BRD-K85232515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22049
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40333
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8421
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26339
Metabolism of lipids	Reactome Pathways 2024	1.0	null
GTEX-TMMY-1926-SM-4DXUU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844477
BRD-K78347804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41425
CAL12T	CCLE Cell Line Gene Expression Profiles	1.0	1.76419
BRD-K64245731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05246
hippocampus (cortex Ammonis)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15774
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basis	GeneRIF Biological Term Annotations	1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223306
BRD-K62102480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59569
Perturb_8197_KD_TRIM56_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Aplasia/Hypoplasia Of The Eyebrow	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K32854540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03258
BRD-K20495487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47109
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06702
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
B-lymphocyte cell line	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4737
alopecia	HPO Gene-Disease Associations	1.0	null
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54015
16353136-Table4	GeneSigDB Published Gene Signatures	1.0	null
Perturb_2837_KD_CDK12_SRP073459	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.7615
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65908
BRD-K49903196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23189
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39465
BRD-K48266244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28664
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11818
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75419
CALU6	CCLE Cell Line Gene CNV Profiles	1.0	1.39643
biological_process	GO Biological Process Annotations 2015	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04008
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	192.429
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.324
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25902
Juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PSIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90579
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
pdx1_22135308_duodenum_lof_mouse_gpl1261_gds4348	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.043607
Recurrent Respiratory Infections	DisGeNET Gene-Phenotype Associations	1.0	null
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20924
BRD-K43896262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20837
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
SRGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21603
PMC10994228-MOL2-18-939-s001.pdf-26-TBX3_TBX3	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01425
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.980542
Perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MEL270	DepMap CRISPR Gene Dependency	1.0	6.31642
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92709
membrane lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24608
hsa-miR-3175	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6376
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4972
H1-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1365
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77833
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	1.9435
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00107
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89379
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911106
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
BRD-K18887540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09133
Seborrheic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964677
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51236
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962121
erastin-6364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ABCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2641
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.6871
KCL22	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77495
everted lower lip vermilion	HPO Gene-Disease Associations	1.0	null
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12937
Chronic Otitis Media	DisGeNET Gene-Disease Associations	1.0	null
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21727
BRD-K28029070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02263
BRD-K74039237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78929
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05402
Perturb_8160_KD_NSUN2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.2884
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11925
cation binding	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lipoprotein biosynthetic process	GO Biological Process Annotations 2023	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6188
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TSPAN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40616
BRD-K89089981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69296
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895996
SUM52PE	DepMap CRISPR Gene Dependency	1.0	3.82225
PMC10326603-cd-22-0620_supplementary_tables_s1-s24_suppst1.xlsx-Table_S18-Supplementary_Table_S18_Patterns_of_gene_alterations_in_TP53_and_or_RB1_mutant_and_wild-type_cohorts_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.986801
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.34249
complete neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.585
Eczema_Integument_GSE6012	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.43424
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K57476199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14846
HLC1	CCLE Cell Line Gene Expression Profiles	1.0	1.63783
short finger	HPO Gene-Disease Associations	1.0	null
regulation of mucus secretion	GO Biological Process Annotations 2025	1.0	null
A-CA-04-2009(H1N1)_4day-RIPK3KO_None_GSE51526	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45046
BRD-K49528360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42661
BRD-K93726930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0206
Icthyosis	DisGeNET Gene-Disease Associations	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.0783
BRD-K78007953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.89219
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3081
epidermoid	GeneRIF Biological Term Annotations	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.2527
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185404
stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.3604
BRD-K86711517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06712
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05402
abnormal epidermis stratum granulosum morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K14865132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10323
PMC11657369-12951_2024_3025_MOESM2_ESM.xlsx-PC-3-NR2F1-AS1-pulldown-Gene_names_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23800773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39113
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12454
PMC11193738-41467_2024_48647_MOESM8_ESM.xlsx-Data_S5-Data_S5_HNF4A-bound_gene_targets_identified_from_ChIP-Seq_in_hepatic_cells_D8_Hep_and_HepG2_cells_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Abnormality Of The Dentition	DisGeNET Gene-Phenotype Associations	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080611
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.987
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
differentiation	GeneRIF Biological Term Annotations	1.0	null
Presubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22578
Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	95.7941
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UB-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A25537246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62594
BRD-K09232527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61721
long-chain fatty acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
small nail	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13096
Rectum adenocarcinoma_READ_TCGA-CL-5917-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34604637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38852
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
LMNA	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6660_OE_Mir29a/Mir29b1_SRP220297	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.28938
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73643
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
sepsis	HPO Gene-Disease Associations	1.0	null
PR-DUB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41877
APLP2_KO_GDS4414_536_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K08241590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34837
positive regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
BRD-K95014616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47748
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1
Perturb_8107_KD_FIP1L1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.04073
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H292 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
aplasia/hypoplasia of toe	HPO Gene-Disease Associations	1.0	null
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26369
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89379
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MP-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lipid modification	GO Biological Process Annotations 2025	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16723
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94831
Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.056898
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.828904
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K18345677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04689
Ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.854
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08298
ELN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24352
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7535
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48709
monocarboxylic acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77398
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49592
whose	GeneRIF Biological Term Annotations	1.0	null
Cicatricial ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
mRNA_TCF3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PRKACB_knockdown_91_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7378
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28604
BRD-K55508908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39854
Perturb_8159_KD_MTPAP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.39538
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
scaly skin	MGI Mouse Phenotype Associations 2023	1.0	null
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835624
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17539
abnormal elasticity of skin	HPO Gene-Disease Associations	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90967
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63631
transient cerebral ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.485125
AF-31-RV78_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237157
Autosomal dominant mutilating palmoplantar keratoderma with periorificial keratotic plaques	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60054
nonbullous	GeneRIF Biological Term Annotations	1.0	null
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063217
BRD-K57274378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73425
BRD-K96925976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64092
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36989
PMC6042247-NIHMS966841-supplement-Sup_Table_2.xlsx-Gene_Sets-FEV_FEV	Rummagene Transcription Factor Associations 2026	1.0	null
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39906
ALOXE3	Pathway Commons Protein-Protein Interactions	1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25015
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04863
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A5XV-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aplasia/hypoplasia involving bones of the feet	HPO Gene-Disease Associations	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29702569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33174
Squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
RCM1	CCLE Cell Line Gene Expression Profiles	1.0	1.56754
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60822
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K78262424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28065
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52234
EHMT2_KD_GSE34925_693_human_MDA-MB231 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62072978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16311
PRDM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17615
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31025
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57535
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25308
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	1.33443
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5759
PROSER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02677
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75065
protein lipidation	GO Biological Process Annotations 2025	1.0	null
KYSE450	CCLE Cell Line Gene Expression Profiles	1.0	1.97147
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.36105
congenital	GeneRIF Biological Term Annotations	1.0	null
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83739
MRPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17632
loss	GeneRIF Biological Term Annotations	1.0	null
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897592
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02116
mRNA_RHOX6_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
LS411N	DepMap CRISPR Gene Dependency	1.0	2.03741
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24017
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39529
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.78578
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09118
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.759
aplasia/hypoplasia involving bones of the upper limbs	HPO Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-8065-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87866
BRD-K56488838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69467
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61438
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066046
protein modification process	GO Biological Process Annotations 2025	1.0	null
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48789
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57704
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-SOX2_partners-SOX2_known_protein_partners_according_to_BioGrid_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.848387
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47526
TRPM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04503
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826452
arachidonic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
NCIH1755	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87255
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13164
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05335
BRD-K17122222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02824
Perturb_14503_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.23682
ENSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95037
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11898
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	1.78199
BRD-K67183010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37253
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81937
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36668
KO52	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66703
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37527
BRD-K71817857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03535
BRD-K16626032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46269
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63733
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89934
BRD-K23591737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01712
BRD-K95850342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16233
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09909
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08939
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2273
PYGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25487
PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K98272474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43328
linoleate 9S-lipoxygenase activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40145
Harlequin Fetus	DisGeNET Gene-Disease Associations	1.0	null
superficial stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22207
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1028
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883367
IM9	DepMap CRISPR Gene Dependency	1.0	2.33651
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.33137
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4377
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30015
ceramide metabolic process	GO Biological Process Annotations 2015	1.0	null
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.187719
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8156_KD_FTO_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.79506
MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01766
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59347
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25046
SNU478	DepMap CRISPR Gene Dependency	1.0	3.49524
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02199
origin	GeneRIF Biological Term Annotations	1.0	null
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.2148
MCIXC	DepMap CRISPR Gene Dependency	1.0	2.08549
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K78315404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14625
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86504
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27008
iron ion binding	GO Molecular Function Annotations 2015	1.0	null
Becker	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42247
hotspots	GeneRIF Biological Term Annotations	1.0	null
NCIH522	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04294
BRD-K16695519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06665
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58456
BRD-K77601667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98018
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66783
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74593
BRD-K02783902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28543
Lung squamous cell carcinoma_LUSC_TCGA-77-8143-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57522
Sjogren-Larsson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
CRCGN014_HEPG2_3H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82353
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.333651
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3333
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861253
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31171
cellular process	GO Biological Process Annotations 2015	1.0	null
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	GO Molecular Function Annotations 2015	1.0	null
Autosomal recessive congenital ichthyosis 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
PA-TU-8988T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064456
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
efficient	GeneRIF Biological Term Annotations	1.0	null
BRD-K21864149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49458
BRD-K25982056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56083
positive regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
RAB33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11228
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.269
intermediate part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84004
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.46198
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50832
pontine reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16683
KRAS.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BRD-K53900606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03248
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05958
BRD-K20984459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47037
Perturb_7628_KD_HNRNPL/UPF1_SRP129007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.91964
Eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00675
BRD-K64767126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78082
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07927
single-organism biosynthetic process	GO Biological Process Annotations 2015	1.0	null
BRD-K44797874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22825
Psoriasis vulgaris_Skin tissue_GSE6710	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.59696
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.15334
Erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73043
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0369
regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0018
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3913
aplasia/hypoplasia of the eyebrow	HPO Gene-Disease Associations	1.0	null
BRD-K44975377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16914
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
pyramidal layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43836
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7769-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41397
pparalpha	GeneRIF Biological Term Annotations	1.0	null
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30391
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Exfoliative Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
elox3	GeneRIF Biological Term Annotations	1.0	null
water homeostasis	GO Biological Process Annotations 2015	1.0	null
BRD-K79877849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04339
Congenital Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
regulation of secretion	GO Biological Process Annotations 2015	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.80008
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67952
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04875192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69514
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048453
BRD-K14309706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84815
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K16988512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45568
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81941
molecular_function	GO Molecular Function Annotations 2015	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2345
BRD-K13782363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69198
Hyperkeratosis	DisGeNET Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35999
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial iron-sulfur cluster assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.627
abnormality of the nail	HPO Gene-Disease Associations	1.0	null
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.047
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5028
Field CA1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50366
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08573
BRD-K82362034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02769
BRD-K77663497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30259
RASL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13551
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16776
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85768
OSBPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51897
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	1.91783
binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_15392_KD_CHD6_SRP399677	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.07185
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80343
Ichthyosiform Erythroderma, Congenital	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K32444429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29202
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.493
long-chain fatty acid biosynthetic process	GO Biological Process Annotations 2023	1.0	null
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23425
BRD-K65598127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26581
Autosomal recessive congenital ichthyosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.639
BRD-K09304381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06521
A253	GDSC Cell Line Gene Expression Profiles	1.0	2.05635
HS821T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09467
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11689
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968148
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLB985	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3938
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
SW48	CCLE Cell Line Gene Expression Profiles	1.0	1.70189
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K23204014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39917
BRD-K20091931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4203
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
followed	GeneRIF Biological Term Annotations	1.0	null
been	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive congenital ichthyosis 2	ClinVar Gene-Phenotype Associations	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2152
ESCRT III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1366
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23505
BRD-K22093396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20551
Subiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32078
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66226
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827085
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.746227
HELA	BioGPS Cell Line Gene Expression Profiles	1.0	1.43532
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22627
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37379
BRD-K98496939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03069
abnormality of the sweat gland	HPO Gene-Disease Associations	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16127
DUSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44812
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3492
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
growth delay	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8196_KD_TIAL1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.134
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65764
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42996
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62714
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19467
hepoxilin biosynthetic process	GO Biological Process Annotations 2015	1.0	null
seborrheic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.830279
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27252
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16784
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842928
Perturb_439_KD_MEP50_SRP073189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.37133
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21366
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5971224__F1	PFOCR Pathway Figure Associations 2024	1.0	null
regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
Ainhum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
MMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77625
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11689
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2095
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43288
phentolamine-2323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32366
BRD-K47650707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03154
BRD-K08442552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21892
BRD-K03221986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07299
abnormality of cardiac morphology	GWASdb SNP-Phenotype Associations	1.0	0.598473
COLO205	DepMap CRISPR Gene Dependency	1.0	2.71501
signal	GeneRIF Biological Term Annotations	1.0	null
KYSE-450	GDSC Cell Line Gene Expression Profiles	1.0	1.80748
Perturb_6871_KD_HHEX_SRP323378	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.92925
Autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65918
NDUFA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72518
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56552
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	5.72512
Perturb_8154_KD_CPSF6_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.62822
Autosomal recessive congenital ichthyosis 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
BRD-K34839838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17507
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206178
abnormality of the eyelid	HPO Gene-Disease Associations	1.0	null
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04444
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43700313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5419
aplasia/hypoplasia of fingers	HPO Gene-Disease Associations	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K11113009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.295
Prostate adenocarcinoma_PRAD_TCGA-J4-A83I-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75745696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6173
Autosomal recessive congenital ichthyosis 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
risk	GeneRIF Biological Term Annotations	1.0	null
PMC12405659-CTM2-15-e70437-s001.xlsx-Supplementary_Table_5-BioGrid-interaction_protein_with_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K90702609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89463
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
Perturb_500_KD_RL6/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.45696
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9173
positive regulation of secretion	GO Biological Process Annotations 2023	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.26255
KMS11	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3969
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09023
Lung squamous cell carcinoma_LUSC_TCGA-77-8144-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33632
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26396
oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66394
BRD-K65496998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75754
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BICR16	CCLE Cell Line Gene Expression Profiles	1.0	2.13712
abnormal skin physiology	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088013
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864415
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79734
Sarcomatoid Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	3.76136
amounts	GeneRIF Biological Term Annotations	1.0	null
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.74777
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
Integrin alpha6-beta4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
liminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28604
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1876
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stroke	HuGE Navigator Gene-Phenotype Associations	1.0	null
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
linoleic acid metabolic process	GO Biological Process Annotations 2025	1.0	null
depression	GWASdb SNP-Phenotype Associations	1.0	0.345385
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84166
regulation of mapk cascade	GO Biological Process Annotations 2015	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
aplasia involving bones of the extremities	HPO Gene-Disease Associations	1.0	null
Perturb_5938_KD_NCOA7_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.95681
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27448
eclabion	HPO Gene-Disease Associations	1.0	null
BRD-K60758969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3324
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31995
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25446
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879647
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4734
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.0602
abnormality of the lung	HPO Gene-Disease Associations	1.0	null
clinical	GeneRIF Biological Term Annotations	1.0	null
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31907
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23718
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Collodion Fetus	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
active	GeneRIF Biological Term Annotations	1.0	null
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
layer 5 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81992
Skin disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K33637419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5131
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17279
FBRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86966
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23264
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1878
HIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01828
BRD-K90460185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24141
BRD-K21423050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15071
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80087
BRD-K13559806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0959
TRMT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03936
GATA1	ENCODE Transcription Factor Targets	1.0	null
cytosol	GO Cellular Component Annotations 2015	1.0	null
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03013
LTBR_INHIBITION - 27 Day_GDS2004_736_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07633
BRD-K02420839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49041
Smc5-Smc6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.861
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.848006
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237303
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38761
ARID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09374
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109257
hepoxilin biosynthetic process	GO Biological Process Annotations 2023	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Setleis syndrome_Skin fibroblast_GSE16524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.45838
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61907
external genital hypoplasia	HPO Gene-Disease Associations	1.0	null
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.924457
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05968
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.172303
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57849
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12822
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44097
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.945816
Synthesis of 12-eicosatetraenoic acid derivatives	Reactome Pathways 2014	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.19655
FUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81731
abnormality of the foot	HPO Gene-Disease Associations	1.0	null
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0132
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
PMC12147031-NIHMS2026129-supplement-Supplemental_Material__Tables__Figures__and_original_Blots.pdf-19-ENSG00000269707_POU3F3	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital ichthyosiform erythroderma	ClinVar Gene-Phenotype Associations 2025	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
BRD-K44643967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17771
NCIH1755	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63127
BRD-K80483148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18926
BRD-K31796953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05926
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74721
studies	GeneRIF Biological Term Annotations	1.0	null
PANC1005	DepMap CRISPR Gene Dependency	1.0	2.8443
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.887348
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5165
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5178
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
compound	GeneRIF Biological Term Annotations	1.0	null
aplasia/hypoplasia involving bones of the lower limbs	HPO Gene-Disease Associations	1.0	null
intermediate stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18137
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43088
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056892
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
BRD-K04680784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89763
Lung squamous cell carcinoma_LUSC_TCGA-77-8131-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-80-DR66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225343
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87336
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K57271749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33333
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57552
UMUC7	DepMap CRISPR Gene Dependency	1.0	4.05802
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.895546
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63500288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09801
Carcinoma, Granular Cell	DisGeNET Gene-Disease Associations	1.0	null
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32856
Palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.332
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.55142
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10504
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22418
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71687
BRD-K61934967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25748
BRD-K50563598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49542
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05594
subpallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27452
Ichthyosis, Lamellar	CTD Gene-Disease Associations	1.0	2.88009
mantle zone of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98904
ncie	GeneRIF Biological Term Annotations	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.36498
Nail Abnormality	DisGeNET Gene-Phenotype Associations	1.0	null
PMC9846571-Table_1.xls-1-NFE2L2_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02852
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20636
BRD-K94090114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01788
Vulva carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
Perturb_15430_KD_CDK7_SRP179971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Ichthyosis vulgaris	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.383
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	291.347
LC1SQSF	CCLE Cell Line Gene CNV Profiles	-1.0	-1.732
ME-180	GDSC Cell Line Gene Expression Profiles	1.0	2.53573
Hypertrophy	CTD Gene-Disease Associations	1.0	1.23137
TE6	CCLE Cell Line Gene Expression Profiles	1.0	1.43919
POLR2A	ENCODE Transcription Factor Targets	1.0	null
ADA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.218
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ichthyosis	GeneRIF Biological Term Annotations	1.0	null
BRD-K32983008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71285
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24271
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15228
Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.145058
NCIH1993	DepMap CRISPR Gene Dependency	1.0	3.08261
Hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
BRD-K61220066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06161
cefmetazole-6086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUJ4-1626-SM-4BONV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83694
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96581
KU-19-19	GDSC Cell Line Gene Expression Profiles	1.0	1.6337
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.12485
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064514
BRD-K46412655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07697
HS821T	CCLE Cell Line Gene CNV Profiles	1.0	1.59376
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01078
abnormal lipid homeostasis	MPO Gene-Phenotype Associations	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051078
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39449566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05415
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886195
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14084
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885914
BRD-K97624648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16884
BRD-K58232861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38691
VDR-20736230-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
BRD-K15008902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15522
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09508
SUM 159PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72146
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42515
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19221
autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
BRD-K17171256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25611
Perturb_2779_OE_ACF7_SRP109301	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.11944
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26369
Perturb_2385_KO_ASXL2_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.86429
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042586
PPARA_KO_GDS2886_484_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29703
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66952
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59347
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K53379620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55821
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
lox	GeneRIF Biological Term Annotations	1.0	null
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3327
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.500035
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A78T-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76425_1_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32925
PMC6778131-41467_2019_12494_MOESM13_ESM.xlsx-Figure_S3b-BCL2-MYC_Day_75_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76269
Prostate adenocarcinoma_PRAD_TCGA-HC-8264-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
long-chain fatty acid metabolic process	GO Biological Process Annotations 2023	1.0	null
shown	GeneRIF Biological Term Annotations	1.0	null
hydrolase	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68135
SNU503	CCLE Cell Line Gene Expression Profiles	1.0	1.36523
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06613
hek-293t cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.463787
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.27801
Perturb_499_KD_PKR/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.8738
PMC9825391-41467_2022_35592_MOESM4_ESM.xlsx-MAF_Targeted_Seq_mutations-Unnamed_47_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2171	COSMIC Cell Line Gene Mutation Profiles	1.0	null
unsaturated fatty acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69033
IGDCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41634
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00581
Integumentary system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.09928
BRD-K98224452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05443
SP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2068
BRD-K51787437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24962
Perturb_6630_KO_TEAD1_SRP315348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.4545
abnormality of immune system physiology	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
skin epidermis development	GO Biological Process Annotations 2025	1.0	null
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3413
BRD-K25236390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34789
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70121
BRD-K50685439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3688
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37175
GSE62974_1_v_0_epas1_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09159
GSE239844_4_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9432
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13235
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BI-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.870811
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15613
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.48938
Perturb_12935_KD_CDK9_SRP340404	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.41149
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918264
PMC10340243__F5	PFOCR Pathway Figure Associations 2024	1.0	null
positive regulation of signaling	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A5QV-01A-22R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain ischemia; cardiovascular diseases; coronary disease; stroke	GAD Gene-Disease Associations	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9886
BRD-K18178356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72341
Bullous congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34084
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20716
MXI1	ENCODE Transcription Factor Targets	1.0	null
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29704
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.349105
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35911
lipid oxidation	GO Biological Process Annotations 2023	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39397248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17285
Midbrain reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01516
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.91178
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10065
arthrogryposis, renal dysfunction, and cholestasis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30911
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9347
Perturb_7307_KD_IER3_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.4318
ROS50	DepMap CRISPR Gene Dependency	1.0	2.35131
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2764
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8503
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11612
sp1signalling	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57994
GSK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40894
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87398
BRD-K93927229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.217
corneal erosion	HPO Gene-Disease Associations	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.18456
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18789
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of localization	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02904
Hyperplasia	CTD Gene-Disease Associations	1.0	1.07911
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08389
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
TSPYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5839
spectrum	GeneRIF Biological Term Annotations	1.0	null
PMC7523182-Table_2.XLSX-Lipid_metabolism_pathways-AHRR_AHRR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08479
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.65091
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92709
BRD-K93611325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40234
12(R)-HPETE	HMDB Metabolites of Enzymes	1.0	null
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68416
KYSE520	CCLE Cell Line Gene Expression Profiles	1.0	1.63335
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_1290_KO_Lef1_SRP111197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.02017
17616640-Table3	GeneSigDB Published Gene Signatures	1.0	null
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10417
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
GSE168676_2_v_3_dach1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95251122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38701
POU5F1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2023	1.0	null
NB6	DepMap CRISPR Gene Dependency	1.0	2.68281
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-11A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6323
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75869095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4632
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11138
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.7038
BRD-K31616862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1129
BRD-K34297711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54427
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09457
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.426693
496100379_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63426
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053166
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.075
positive regulation of secretion	GO Biological Process Annotations 2025	1.0	null
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48469
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47581
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37517
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929166
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861683
lymphoid cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
membrane lipid metabolic process	GO Biological Process Annotations 2023	1.0	null
BRD-K62650632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49471
IRF6_KO_GDS2359_126_mouse_skin E17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6629_KO_TEAD1_SRP315348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
santonin-4353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.226
ceramide metabolic process	GO Biological Process Annotations 2023	1.0	null
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.989982
BRD-K01668149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11602
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11888
BRD-K00078503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44922
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53413
Congenital Nonbullous Ichthyosiform Erythroderma	DisGeNET Gene-Disease Associations	1.0	null
16489042-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
Leukemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
PK59	CCLE Cell Line Gene Expression Profiles	1.0	2.04783
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04444
MAPK1_knockdown_112_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73333
SNU719	CCLE Cell Line Gene Expression Profiles	1.0	1.78778
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1763
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4362
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21061
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966085
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97235
one	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.82416
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
BRD-K17040651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28952
BRD-K41707029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28772
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21048
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
vitamin c_mus musculus_gpl6246_gse19378	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.914829
abnormal lipid level	MGI Mouse Phenotype Associations 2023	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
hepoxilin metabolic process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74862
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2062
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32751688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1026
TMEM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7054
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82182
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31741
abnormality of the face	HPO Gene-Disease Associations	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.451
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1774
CRCGN015_MCF10A_48H:J12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82884
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05814
abnormality of joint mobility	HPO Gene-Disease Associations	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94152
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60705
cellular_component	GO Cellular Component Annotations 2015	1.0	null
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93849
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.09892
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851982
BRD-K54285478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10521
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.106089
BRD-K76543697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07025
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00741
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41495
RERF-LC-MS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-520	GDSC Cell Line Gene Expression Profiles	1.0	2.21652
BRD-K97373334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42915
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.22
Cornified envelope formation	KEGG Pathways 2026	1.0	null
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18328
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC1894940__F5	PFOCR Pathway Figure Associations 2023	1.0	null
individuals	GeneRIF Biological Term Annotations	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8268
BRD-K77221872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5608
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856672
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.059
furegrelate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37899
Lipoxygenase, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60898
contribution	GeneRIF Biological Term Annotations	1.0	null
BRD-K28698418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13002
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	2.43958
Perturb_16813_OE_HNF1A/FOXA3/PROX1/SIRT1/PGC1A/AMPK_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36084
abnormality of the helix	HPO Gene-Disease Associations	1.0	null
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32755
Hair root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40701
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54779
BRD-K65987370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13659
Acute Myeloid Leukemia_LAML_TCGA-AB-2911-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.85964
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960922
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of PrS (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11298
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	4.00176
dry skin	MPO Gene-Phenotype Associations	1.0	null
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1878
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26668
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5077-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46152990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29471
BRD-K21584435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94944
VBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55819
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ARHGAP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82534
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.071636
Collecting Duct Carcinoma Of The Kidney	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892533
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1292
Neoplasms, Glandular and Epithelial	HuGE Navigator Gene-Phenotype Associations	1.0	null
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80079
skin	GeneRIF Biological Term Annotations	1.0	null
icosanoid metabolic process	GO Biological Process Annotations 2015	1.0	null
xray	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84G-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
d11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
BRD-K60812542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16502
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71252
Arachidonic acid metabolism	Reactome Pathways 2014	1.0	null
BRD-K01162126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82737
MKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48364
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.74145
Perturb_16814_OE_HNF1A/FOXA3/PROX1/SIRT1/PGC1A/AMPK_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
sphingolipid biosynthetic process	GO Biological Process Annotations 2025	1.0	null
PMC4515859__F3	PFOCR Pathway Figure Associations 2023	1.0	null
CPTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43829
Lipase/lipooxygenase, PLAT/LH2	InterPro Predicted Protein Domain Annotations	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6358
BRD-K71345532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07028
Birth Weight	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHX58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02337
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.874713
positive regulation of multicellular organismal process	GO Biological Process Annotations 2023	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
ZNF426	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0592
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42304
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	4.26098
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal respiratory system morphology	HPO Gene-Disease Associations	1.0	null
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46364
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19114
Dry Skin, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176779
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33892
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925949
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7377
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.337376
BRD-K07981644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06141
dehydration	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64W-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70093308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54147
Sweat gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.805
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53631
carotid atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648938
BRD-K56563758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56283
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17943
Perturb_7497_KO_G3BP1/G3BP2_SRP192777	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.80187
TRAPPC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11331
preoptic telencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02252
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39826
BRD-K44787496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12185
purification	GeneRIF Biological Term Annotations	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
CRO-AP2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72617
Scape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
BRD-K66248685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7178
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33394
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.611
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03048
BRD-K36689392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10947
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22436
GTEX-S3XE-0926-SM-4AD4S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916073
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09919985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27498
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A31916785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08875
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2896
U343	DepMap CRISPR Gene Dependency	1.0	3.06825
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5675
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05043
BRD-K72934808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32901
Perturb_7385_KO|KD_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
JEKO-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
obesity	GWASdb SNP-Disease Associations	1.0	0.832379
BRD-K52592505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19069
BRD-K68618894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03526
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866047
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13572
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Self-Healing Collodion Baby	DisGeNET Gene-Disease Associations	1.0	null
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18742
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41272
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37367
BRD-K15387690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71254
BRD-K31608682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34515
BRD-K01067435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36359
BRD-K44339278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42281
BRD-K18488784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64984
BRD-K66434795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65809
Lymphoma, Non-Hodgkin	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K58270905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13162
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08898
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89379
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	1.00042
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18577
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.14758
ceramide biosynthetic process	GO Biological Process Annotations 2015	1.0	null
abnormal renal physiology	HPO Gene-Disease Associations	1.0	null
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34758
CENPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15437
BRD-K05699155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21504
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045155
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K38487270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38529
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44312
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44848
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24039
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Alopecia	DisGeNET Gene-Disease Associations	1.0	null
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84904
COV362	CCLE Cell Line Gene Expression Profiles	-1.0	-2.17457
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99253
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36542
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919103
hearing impairment	HPO Gene-Disease Associations	1.0	null
regulation of water loss via skin	GO Biological Process Annotations 2015	1.0	null
Perturb_15469_KD_KLF5_SRP256723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.50873
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826246
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989201
Dehydration	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K68303333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03841
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03307
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55309
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUIT2	DepMap CRISPR Gene Dependency	1.0	3.31618
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K05957858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38276
abnormal	GeneRIF Biological Term Annotations	1.0	null
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.65918
BRD-K18101782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21967
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H6-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.44102
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8162
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.843405
BRD-K74971765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08828
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103907
NCIH1836	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59275
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.174
BRD-K37634338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04125
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058697
BRD-K32235162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85512
Prostate adenocarcinoma_PRAD_TCGA-YL-A8S8-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67814
BRD-K35088248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69893
Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6673-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28604
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8304-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5729
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.738
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32357
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.890117
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31025
BRD-K46742113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13029
BRD-K47895166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26747
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16401
background	GeneRIF Biological Term Annotations	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.035904
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
BRD-K13970506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47005
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3503
icosanoid metabolic process	GO Biological Process Annotations 2023	1.0	null
Retrosplenial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48875
Tonsil	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.248643
BRD-K57228212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43709
BRD-K56950366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01751
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12121_KO_Aire_SRP250736	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.0684
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03781
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29157
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03246
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944309
BRD-K10288935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89519
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72579
Photodamaged Skin	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24445
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05512
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71271
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6750_KO|KD_IER5_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.95875
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30366
BRD-K40419401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38859
RFX5	ENCODE Transcription Factor Targets	1.0	null
ZNF48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55367
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.917637
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.936304
Rectum adenocarcinoma_READ_TCGA-G5-6233-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
long-chain fatty acid metabolic process	GO Biological Process Annotations 2025	1.0	null
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4725
BRD-K52202153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41783
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15102
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44832
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86783
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.08694
BRD-K66253165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19667
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04218
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27756
Perturb_16968_KD_NRF2_SRP218850	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.35511
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25866
hydroxyprogesterone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53739
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
KLHL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68655
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07002
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05133
Small_Intestine-intestinal tuft cell	Tabula Sapiens Gene-Cell Associations	1.0	0.135434
lack of skin elasticity	HPO Gene-Disease Associations	1.0	null
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887066
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04882
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
establishment of skin barrier	GO Biological Process Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83X-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47542
abnormal hair quantity	HPO Gene-Disease Associations	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917226
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867008
PMC1894940__F5	PFOCR Pathway Figure Associations 2024	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0402
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929062
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592043
Perturb_524_KD_RL6/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.27527
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21029
BRD-K04238122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09637
BRD-K09203354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46898
fatty acid metabolic process	GO Biological Process Annotations 2025	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4649
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16737
Eversion Of Lower Lip	DisGeNET Gene-Phenotype Associations	1.0	null
HCC827	CCLE Cell Line Gene CNV Profiles	1.0	1.63589
Keratitis	DisGeNET Gene-Disease Associations	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2502
positive regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
AE-61-UO01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28847
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gingival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43654313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04882
VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
IL17RB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08267
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09219
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060974
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66952
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21423
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912734
Lower epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14578
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N5-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03923
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09549
anhidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.01385
BRD-K15928912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0268
BRD-K25039453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26456
basomedial nucleus (accessory basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03646
loxs	GeneRIF Biological Term Annotations	1.0	null
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45345
Perturb_12149_KO|OE_TP53|CENPA_ERP125655	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.59551
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17943
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980096
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55593
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.23199
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1196	DepMap CRISPR Gene Dependency	1.0	3.45069
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45158
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C1QTNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1997
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94391
BRD-K71817712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04042
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40253
Perturb_16811_OE_HNF1A/FOXA3/PROX1_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12592
BRD-K13130949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08777
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43491
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08682
BRD-K27618188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08425
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83753
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.394
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
Perturb_6602_KD_HOTAIRN_SRP159657	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.41102
Perturb_7389_KO_UPF3A_ERP130415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.14587
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843172
review	GeneRIF Biological Term Annotations	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918264
Hypotrichosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K84601599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21448
cancer	GAD High Level Gene-Disease Associations	1.0	0.300704
chaperones	GeneRIF Biological Term Annotations	1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lipoxygenase pathway	GO Biological Process Annotations 2025	1.0	null
KCNK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43301
JMSU1	DepMap CRISPR Gene Dependency	1.0	2.07189
mantle zone of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11402
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943609
SU8686	CCLE Cell Line Gene Expression Profiles	1.0	1.90564
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967316
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE65617_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.383
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844315
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48501
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49685
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.19424
BRD-K53199675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16644
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865802
Fibrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.344
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91905
heterogeneity	GeneRIF Biological Term Annotations	1.0	null
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.3096
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	1.0	null
JNK_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41312
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44789
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03716
organonitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
growth abnormality	HPO Gene-Disease Associations	1.0	null
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSF1_KD_GDS1733_752_human_HeLa cells - 2 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
flupentixol-6708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
contribute	GeneRIF Biological Term Annotations	1.0	null
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
PMC10175786-Table4.XLSX-Sheet_1-GSE9750_AND_Ferrotosis_genes_NOT_GSE7410_NOT_GSE63514_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69447
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13956
GSE186460_3_v_6_baricitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07657
BRD-K81949875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03593
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	GO Molecular Function Annotations 2015	1.0	null
otitis media	HPO Gene-Disease Associations	1.0	null
Glutathione synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.517
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.51952
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18823
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57963
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.432
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060324
genetic	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15738
aplasia/hypoplasia of the extremities	HPO Gene-Disease Associations	1.0	null
Perturb_8136_KD_G3BP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.46589
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.489327
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43023
most	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06936
REC1	CCLE Cell Line Gene Expression Profiles	1.0	1.36375
abnormality of body height	HPO Gene-Disease Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05692
BRD-K14756138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27524
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95254
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61372
BRD-K12271646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08976
lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.12501
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.0694
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9319
BRD-K11610091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17173
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26075
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59805
BRD-K36537572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17603
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
BRD-A79097167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1994
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12553
PR, GR	MotifMap Predicted Transcription Factor Targets	1.0	null
Holocarboxylase synthetase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
NCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98424
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61221
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31813
KU812	DepMap CRISPR Gene Dependency	1.0	4.66421
BRD-K57357304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42021
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69777784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23127
obesity	GWASdb SNP-Phenotype Associations	1.0	0.598473
epidermal	GeneRIF Biological Term Annotations	1.0	null
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50345
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
developmental	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K95922469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53863
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94439
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111834
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57167256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00948
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943118
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9673_KO_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.65174
reddish skin	MGI Mouse Phenotype Associations 2023	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
BRD-K17821077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3687
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03689
respiratory tract infection	HPO Gene-Disease Associations	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
BRD-K83645749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65328
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19441
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912075
Subiculum, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72868
Perturb_8120_KD_SF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.33641
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83721
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39906
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40591
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.593649
renal insufficiency	HPO Gene-Disease Associations	1.0	null
key	GeneRIF Biological Term Annotations	1.0	null
fatty acid derivative metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
patient	GeneRIF Biological Term Annotations	1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.43125
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35319
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23965
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.231135
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.343591
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06657
serine-type endopeptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915863
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18388
Meningioma	HuGE Navigator Gene-Phenotype Associations	1.0	null
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36824
aplasia/hypoplasia of the nails	HPO Gene-Disease Associations	1.0	null
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354826
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Eczema	DisGeNET Gene-Disease Associations	1.0	null
TE15	CCLE Cell Line Gene CNV Profiles	1.0	1.56905
BRD-K23669327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46381
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AKT1_knockdown_43_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.97705
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923384
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9937
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07138
cognitive impairment	HPO Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7024
intermediate stratum of 5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29763
linked	GeneRIF Biological Term Annotations	1.0	null
recurrent respiratory infections	HPO Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03868
muc5ac	GeneRIF Biological Term Annotations	1.0	null
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03716
BRD-K03383196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25102
Perturb_15517_KD_E2F2_SRP314859	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.03989
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.874
BRD-K39794286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03209
perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17955_KO_Snca_SRP377748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.53163
regulation of mucus secretion	GO Biological Process Annotations 2015	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48721
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050761
BRD-K77718491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11472
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
enlargement	GeneRIF Biological Term Annotations	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.295739
mood disorder	GWASdb SNP-Disease Associations	1.0	0.267868
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
hepoxilin biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8580-01A-31R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25761766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19053
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23041
CTCF	MotifMap Predicted Transcription Factor Targets	1.0	null
hypohidrosis	HPO Gene-Disease Associations	1.0	null
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
Autosomal recessive congenital ichthyosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
Perturb_3589_KO_DDX6_ERP024006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.69482
Vibrissal follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
arachidonate metabolic process	GO Biological Process Annotations 2025	1.0	null
positive regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
functions	GeneRIF Biological Term Annotations	1.0	null
Autosomal recessive congenital ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.54
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24456
Vesiculobullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.961388
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.91208
BRD-K00620786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26754
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4712
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23721
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04488
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15844
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.922799
BRD-K53617314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62948
Hair follicle epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
BRD-K85917058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89781
congenital ichthyosiform erythroderma	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
abnormal joint morphology	HPO Gene-Disease Associations	1.0	null
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35938
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57739
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
BRD-K17482709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55818
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.059
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20398
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888761
termed	GeneRIF Biological Term Annotations	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8621
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16904
BRD-K06318195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15271
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96754
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94152
three	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20958
MIF_DEPLETION_GDS3626_95_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918264
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71861
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77317
BRD-K02681754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90387
BRD-K29903367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28339
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.658
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53339
Perturb_8132_KD_EIF4A3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.5278
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978058
PL45	CCLE Cell Line Gene Expression Profiles	1.0	1.42338
Lung adenocarcinoma_LUAD_TCGA-49-6742-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
BRD-K21826560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26149
BRD-K57724549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35515
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80765
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35077
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23917
BRD-K01793276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6183
Field CA1, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62086
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49592
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.027103
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204001
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2626
Synthesis of 12-eicosatetraenoic acid derivatives	Reactome Pathways 2024	1.0	null
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06619604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43199
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44778
BRD-K13781734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27466
Perturb_9537_OE_Jmjd3_SRP066186	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.51
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2732
Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66453893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68836
BRD-K69585439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17378
BRD-K04834648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24226
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YAPC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00995
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1313
lateral part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40122
mRNA_ESRRB_19136965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_16812_OE_HNF1A/FOXA3/PROX1_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.06746
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	168.175
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62911
SEMA3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90969
short stature	HPO Gene-Disease Associations	1.0	null
496100661_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.87665
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02892
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8059
BRD-K89476396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11272
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.11393
BRD-K89863047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46059
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15985
ABCB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90157
GSE182727_1_v_0_busulfan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KP-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
phenotype	GeneRIF Biological Term Annotations	1.0	null
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.960983
Posterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33394
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02926
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96635
CRCGN016_MCF10A.WT.HP_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22246
BRD-K92399035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97931
MORF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14359
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K89687419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06747
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5002
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0851
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.549359
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.55085
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.11
CCDC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37958
hepoxilin metabolic process	GO Biological Process Annotations 2023	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.76951
BRD-K84118789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25456
BRD-K65315551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5193
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999473
BRD-K62418398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09345
SPOUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0688
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23934
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5878
Lung squamous cell carcinoma_LUSC_TCGA-58-8392-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16167206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05901
lipoxygenase pathway	GO Biological Process Annotations 2015	1.0	null
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
epidermis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.031
Fibroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5475
positive regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
Skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.195
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14827
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94669
dilazep-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32739
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.77
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19126
Perturb_5394_KD_LIM1_SRP402415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.2522
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6045
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67634
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8578301__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K61978712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.015
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41185
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08294
CRCGN015_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4526
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5241
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17767
TT	CCLE Cell Line Gene Expression Profiles	1.0	2.8281
BRD-K68608492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63237
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1065
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00254
genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50502
SRSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06538
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K17840858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16532
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45171
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84904
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27876
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03313
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893785
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08599
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9132
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09502
intermediate stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67332
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46212
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11751
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
HS739T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8974
BRD-K08300592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06199
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39906
BRD-K16789950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08233
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09895564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35908
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24864
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05758
abnormality of the respiratory system	HPO Gene-Disease Associations	1.0	null
BRD-K00765599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02045
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.66
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ceramide biosynthetic process	GO Biological Process Annotations 2023	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10125
Perturb_4922_KD_WTAP_ERP019668	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.76531
BRD-K21196859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17822
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHL1	CCLE Cell Line Gene Expression Profiles	-1.0	-3.08337
BRD-K95860374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26675
Inflammation	CTD Gene-Disease Associations	1.0	1.03641
recurrent infections	HPO Gene-Disease Associations	1.0	null
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
arab	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992175
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	1.02437
ichthyin	GeneRIF Biological Term Annotations	1.0	null
BE-31-XV38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.306059
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12342
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.850384
EN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28969
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94328
colocalization	GeneRIF Biological Term Annotations	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21098
Prostate adenocarcinoma_PRAD_TCGA-XA-A8JR-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34927
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.11519
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48491
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43547
envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.10616
BRD-K95735693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28581
BRD-K45799338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03376
SNU738	CCLE Cell Line Gene CNV Profiles	1.0	2.31002
fatty acid metabolic process	GO Biological Process Annotations 2023	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062446
X-linked chondrodysplasia punctata 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.98
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	2.07078
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDE10A_KO_GDS4542_292_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944309
pc-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314046
BRD-K49384706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04834
carrier	GeneRIF Biological Term Annotations	1.0	null
BRD-K87516578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0964
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
limitation of joint mobility	HPO Gene-Disease Associations	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Hypergranulosis	DisGeNET Gene-Phenotype Associations	1.0	null
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51217
b-lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0025
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.297
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48373
ceramide biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WD-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20171
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22635
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41272
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40408
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
serine-type peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2025	1.0	null
Autosomal recessive congenital ichthyosis 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.257
DENR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43861
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977999
BF-29-LU75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347076
schizoaffective disorder	GWASdb SNP-Disease Associations	1.0	0.500035
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05684
Hypohidrosis	DisGeNET Gene-Disease Associations	1.0	null
Arachidonic acid	HMDB Metabolites of Enzymes	1.0	null
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61639
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994417
nipal4	GeneRIF Biological Term Annotations	1.0	null
Subiculum, ventral part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27373
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46901
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956567
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70735
Photosensitive trichothiodystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89409
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64033
skin epidermis development	GO Biological Process Annotations 2023	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8069_KD_SFPQ_SRP281189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.25624
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1529
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4201
BRD-K66590796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18158
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38319
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of mapk cascade	GO Biological Process Annotations 2015	1.0	null
G-401 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269308
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24701
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Glioma	HuGE Navigator Gene-Phenotype Associations	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27521
PDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32143
BRD-K56424158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10158
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intellectual disability	HPO Gene-Disease Associations	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.978915
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.0423
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23176
HCoV-EMC2012_24Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60988
oxoacid metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30902
abnormality of the teeth	HPO Gene-Disease Associations	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052397
BRD-K89767945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.59798
CRCGN010_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25278
BRD-K69580972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8898
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08752
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33571
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35911
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81G-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V955-1126-SM-4JBH3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916837
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39962
PIK3CD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24736
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22917
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17207
AQP11_Deficiency_GDS3395_578_mouse_Kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925385
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63222
congenital ichthyosiform erythroderma	HPO Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.76561
ichthyosiform erythroderma, congenital	GAD Gene-Disease Associations	1.0	null
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03953
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964759
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901406
Cicatricial lagophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.880325
BRD-K83815065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49502
Sparse Hair	DisGeNET Gene-Phenotype Associations	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.203022
Perturb_2167_KO_Sirt3_SRP403451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.54254
Nucleus of the lateral lemniscus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17192
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
icSARS CoV_36Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.87661
regulation of MAPK cascade	GO Biological Process Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34367
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
OSTC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0957
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
Fatty acid metabolism	Reactome Pathways 2024	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02685
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.27785
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24113
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55238
positive regulation of mucus secretion	GO Biological Process Annotations 2025	1.0	null
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.985305
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-11A-12R-A26B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K74987024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33121
BRD-K50291875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5409
BRD-K67141726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29688
BRD-K43901257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12318
Growth Delay	DisGeNET Gene-Phenotype Associations	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K61533770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13844
brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.293694
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
Abnormality Of The Helix	DisGeNET Gene-Phenotype Associations	1.0	null
Eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.433
Hypohidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
positive regulation of transport	GO Biological Process Annotations 2015	1.0	null
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295594
SARS-dORF6_60Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.64092
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47001
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93418
positive regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
Chorionic villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
Sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051191
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11187
BRD-K08650286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20542
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964677
AHCTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72601
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53429
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261629
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.848387
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5134
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.446569
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
fatty acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Hippocampal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843499
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78691
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.901702
UFSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27944
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41172555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39216
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48413
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
BRD-K25138450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22865
BRD-K20053005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67183
PMC7304214-40170_2020_217_MOESM6_ESM.xlsx-Lipid_signaling_13_e_UP-Li_et_al_2018_GSE88752_Linking_prostate_cancer_cell_AR_heterogeneity_to_distinct_castration_and_enzalutamide_responses_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93646
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCUBM	DepMap CRISPR Gene Dependency	1.0	2.15983
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
CBLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26653
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06208
SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
autosomal	GeneRIF Biological Term Annotations	1.0	null
adipose tissue	HPA Tissue Gene Expression Profiles	-1.0	-1.19655
BRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80796
abnormal hand morphology	HPO Gene-Disease Associations	1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00474
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36115
BRD-K71109636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71644
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28958
BRD-K27888332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69551
GSE185953_1_v_3_tlr3_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of skin physiology	HPO Gene-Disease Associations	1.0	null
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02959
BRD-K57732605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35535
BRD-K52104866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45513
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.0423
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17352
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.956015
BRD-K73479560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17761
GSE131903_0_v_2_abca12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DROSHA_02_145	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
Brain Ischemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.053826
No annotation - 4	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58844
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21306
intensity	GeneRIF Biological Term Annotations	1.0	null
Perturb_3620_KO_SMARCA4_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.12518
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07627
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Trichothiodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_440_KD_PRMT5_SRP073189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.88651
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09962
Sarcoma_SARC_TCGA-DX-A6YQ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072963
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
hsa-miR-653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.9646
External Genital Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37841
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828613
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48827
hepoxilin	GeneRIF Biological Term Annotations	1.0	null
PRDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18746
Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
b-lymphocyte cell line	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormality of the upper limb	HPO Gene-Disease Associations	1.0	null
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69109
Limitation Of Joint Mobility	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929254
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57807
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.754124
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.792545
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.08102
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39906
FYCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98689
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63868
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.98973
LB1047-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-2.00946
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47432
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982348
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
ChaGo-K-1	GDSC Cell Line Gene Expression Profiles	1.0	2.41895
BRD-K06743908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28798
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SW982	DepMap CRISPR Gene Dependency	1.0	4.60569
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90841
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_8092_KD_PUF60_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.665
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27355
BRD-K34445094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53551
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39048
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
PMC12271601-mmc2.xlsx-OUT_cells_01-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13279
ZDHHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23749
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.939895
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44699
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.6042
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76833108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69475
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46887
SERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5669
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865337
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
ESS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95192
BRD-K31575995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05934
PMC5971224__SF1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877312
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.061352
Keratoderma	DisGeNET Gene-Disease Associations	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22207
BRD-K09819684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37004
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07455
BRD-K86077185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89943
DCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.999
CRCGN013_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7823
OXSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84941
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.56217
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.324183
MSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17007
BICR22	CCLE Cell Line Gene Expression Profiles	1.0	1.56177
UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A40504327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17752
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.853116
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75900952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04901
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96361
abnormality of the hair	HPO Gene-Disease Associations	1.0	null
BRD-K24525269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5655
CPC-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
form	GeneRIF Biological Term Annotations	1.0	null
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41736
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11647
BRD-K71631414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59892
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
arachidonate 12(S)-lipoxygenase activity	GO Molecular Function Annotations 2025	1.0	null
lipoprotein biosynthetic process	GO Biological Process Annotations 2025	1.0	null
CAL851	CCLE Cell Line Gene CNV Profiles	1.0	1.44315
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50779
Lack Of Skin Elasticity	DisGeNET Gene-Phenotype Associations	1.0	null
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243699
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6971
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01504
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.64072
LEPROT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0654
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19712167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13856
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090366
BRD-K09468701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10218
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.531
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37132
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03481
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062663
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24684
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K81751970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18664
Glutaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.053
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64575
RAD21	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lamellar ichthyosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46651
BRD-K41700289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02108
hypohidrosis or hyperhidrosis	HPO Gene-Disease Associations	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.614
LMNB1_02_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.12338
BRD-K15532741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01323
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.935768
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tacrine-6698	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10154
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0811
Perturb_9645_KO_HES7_SRP153047	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49096
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13312
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18103
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35754
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59347
BRD-K48050202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27785
BRD-K31624501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71899
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98918
CRCGN012_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07475
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81932
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.053
VRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68677
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCC9	CCLE Cell Line Gene Expression Profiles	1.0	2.25278
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
regulation of body fluid levels	GO Biological Process Annotations 2015	1.0	null
BRD-K81888673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63639
thin nail	HPO Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873267
regulation of transport	GO Biological Process Annotations 2015	1.0	null
carboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
SYNCRIP_KD_GDS3578_86_human_MM1S	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K82765368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27902
SKMG1	DepMap CRISPR Gene Dependency	1.0	6.35916
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27277
positive regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
BRD-K27823380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69801
BRD-K11504463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71796
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0656
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34087
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02723
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38439
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2461
CRCGN017_MCF10A.TP53.M_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24573
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98238
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K23203419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22765
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05895
BRD-K56332068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02304
PMC2742785__F8	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K57830670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07709
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977602
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.963513
GSE146687_2_v_1_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
establishment of skin barrier	GO Biological Process Annotations 2015	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPMI-6666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
unsaturated fatty acid metabolic process	GO Biological Process Annotations 2023	1.0	null
reddish skin	MPO Gene-Phenotype Associations	1.0	null
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.305
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989201
BRD-K82827604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21404
BRD-K52989901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38471
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2315
BRD-K21955896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00985
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
methylphenidate_mus musculus_gpl11180_gse33619	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Octadecanoid formation from linoleic acid	WikiPathways Pathways 2024	1.0	null
lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980141
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
solubility	GeneRIF Biological Term Annotations	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4048
Autosomal recessive congenital ichthyosis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
Autosomal recessive congenital ichthyosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.081
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93076
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
Perturb_4141_KO_Apoe_SRP131850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.46672
Hair follicle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RMGI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34214
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16597
abnormality of the lip	HPO Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41606
AIRE_KO_GDS2274_246_mouse_Medullary thymic epithelial cells (with high CD80 expression)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934986
isoenzyme	GeneRIF Biological Term Annotations	1.0	null
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08276
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73724
presented	GeneRIF Biological Term Annotations	1.0	null
BRD-K37740343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35823
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
sphingolipid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4688
Cerebral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25347
BRD-K75135426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1834
milligram	GeneRIF Biological Term Annotations	1.0	null
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the immune system	HPO Gene-Disease Associations	1.0	null
CHILD syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
BFTC905	DepMap CRISPR Gene Dependency	1.0	2.7657
Arachidonate metabolism	Reactome Pathways 2024	1.0	null
Acanthosis	DisGeNET Gene-Phenotype Associations	1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49083
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59724
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
unsaturated fatty acid metabolic process	GO Biological Process Annotations 2025	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.046286
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
common	GeneRIF Biological Term Annotations	1.0	null
PMC7579924-12920_2020_778_MOESM3_ESM.xlsx-AA-Gene_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57673
BRD-K17850764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25877
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	1.0	1.40994
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vulva squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
BRD-K46936325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08659
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.46655
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.344935
BRD-K14241686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55555
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.059
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900786
selfhealing	GeneRIF Biological Term Annotations	1.0	null
positive regulation of multicellular organismal process	GO Biological Process Annotations 2025	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19986
sphingolipid metabolic process	GO Biological Process Annotations 2015	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.82497
aloxe3	GeneRIF Biological Term Annotations	1.0	null
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00255
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5459-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35151
lipid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75014
families	GeneRIF Biological Term Annotations	1.0	null
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lipoxygenase	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K09271653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1465
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28705
BRD-K43435656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07617
BRD-K13204142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13711
allelic	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35976
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77302
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11503
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60408
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.262
abnormal skin condition	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K47801291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20164
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0141
BRD-K03116010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04006
short digit	HPO Gene-Disease Associations	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
abnormality of corneal epithelium	HPO Gene-Disease Associations	1.0	null
Perturb_11437_KD_NFYA_SRP264974	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.41763
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20189
lipid oxidation	GO Biological Process Annotations 2025	1.0	null
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853087
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942085
BRD-K11726285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00279
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895278
discovery	GeneRIF Biological Term Annotations	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Netherton syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.984
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40603
ZNF658	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29785
RT112	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3324
Perturb_14086_KO_USP22_SRP199797	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.69748
dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.085418
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22599
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75266
regulation of mucus secretion	GO Biological Process Annotations 2023	1.0	null
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34227
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mild	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
corticosterone-4064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mantle zone of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31025
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103907
BRD-K38118226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40077
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13775
Perturb_15422_KD_PXN_SRP199368	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.1257
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4653-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
artery wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185404
Perturb_2744_KD_MUC1_SRP214243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.26461
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1272	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66622
CRCGN014_HEPG2_3H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25216
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00658
skin	HPA Tissue Protein Expression Profiles	1.0	2.04572
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55771
Metabolism of lipids and lipoproteins	Reactome Pathways 2014	1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72936
showed	GeneRIF Biological Term Annotations	1.0	null
BRD-K53146097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27841
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
Necrosis	CTD Gene-Disease Associations	1.0	1.14404
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87398
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K40361885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60955
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11689
BRD-A34842997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06005
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.724041
second	GeneRIF Biological Term Annotations	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26224
AMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87712055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98674
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41713
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30184
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.870088
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Arachidonic acid	MW Enzyme Metabolite Associations	1.0	null
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87249
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC4367834-12864_2014_6889_MOESM9_ESM.xlsx-Network_Parkinson_s_Disease-TBP_TBP	Rummagene Transcription Factor Associations 2026	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84713
BRD-K21635266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65129
CaR-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58528
Calu-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4746_KD_APOBEC3B/APOBEC3C/APOBEC3F_SRP050149	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.42611
HSF1_KD_GDS1733_757_human_HeLa cells - 4 Hour by siHSF1_2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KYM1	DepMap CRISPR Gene Dependency	1.0	16.6043
Perturb_15418_OE_KDM4B_SRP194543	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.9542
Perturb_8226_KD_EWSR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.82528
BRD-K28247259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48736
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
PPP1R15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34176
BRD-K81471597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05216
NCIH2087	CCLE Cell Line Gene CNV Profiles	1.0	1.75111
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2452
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45725
aplasia/hypoplasia involving bones of the hand	HPO Gene-Disease Associations	1.0	null
Papillary Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2373
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K39247583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61548
YD8	CCLE Cell Line Gene CNV Profiles	1.0	1.52669
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2229
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
thickened skin	HPO Gene-Disease Associations	1.0	null
PLAT/LH2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K75688032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73843
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01431
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07418
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.622
Perturb_8087_KD_EIF4G2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.70493
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08215
Ovarian Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42631
BRD-K65438558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05383
unknown	GeneRIF Biological Term Annotations	1.0	null
Forearm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.72623
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.10048
GTEX-UJMC-0926-SM-4IHLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901455
BRD-K77519898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10545
KRAS.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07546
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.78705
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32309
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.59069
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12553
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74031
GSE221077_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K74873856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41345
intermediate stratum of p2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45656
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66205
Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59456
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21937
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989201
NR6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89132
BRD-K73462370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27473
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78093
abnormality of the lower limb	HPO Gene-Disease Associations	1.0	null
erk	GeneRIF Biological Term Annotations	1.0	null
regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
abnormal skin morphology	MPO Gene-Phenotype Associations	1.0	null
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1498
regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
orphenadrine-3801	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEC59	DepMap CRISPR Gene Dependency	1.0	2.42621
Epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.971
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01397
Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arachidonic acid metabolism	KEGG Pathways 2026	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane lipid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Ichthyosiform erythroderma, Brocq congenital, nonbullous form	CTD Gene-Disease Associations	1.0	2.88009
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.246
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0229
ioversol-6726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0745
Parallel fiber to Purkinje cell synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.14183
Subiculum, dorsal part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76366
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16046
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63267
Megaconial type congenital muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
BRD-K95573463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36753
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976563
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.989546
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.828967
PMC3109859__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35489
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.88778
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	1.58682
BRD-K84062787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78356
Perturb_9371_OE_HIC2_SRP317427	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.83198
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942461
BRD-K60460300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4461
CDK9_knockdown_104_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.53699
BRD-K86349956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42579
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59654
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4257
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00387
icosanoid metabolic process	GO Biological Process Annotations 2025	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94152
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13323
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SS18L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.878
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
HCT15	BioGPS Cell Line Gene Expression Profiles	1.0	1.0326
Anhidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
oxidation-reduction process	GO Biological Process Annotations 2015	1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8429
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.321
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857708
Perturb_7309_KD_IER3AS1_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
KRT5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954483
linoleate 9S-lipoxygenase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14311
PMC7217064-IJC-146-3354-s004.xlsx-Table_S5-Supplementary_Table_S5_Genes_significantly_upregulated_in_OC2-transfected_AGS_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855637
BRD-K82609503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18461
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK3B_KD_GDS4305_183_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
possibility	GeneRIF Biological Term Annotations	1.0	null
hair follicle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09546
TE9	CCLE Cell Line Gene Expression Profiles	1.0	1.84871
alox12b	GeneRIF Biological Term Annotations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Scalp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.612152
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.059
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56412
amide biosynthetic process	GO Biological Process Annotations 2023	1.0	null
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90202
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81302
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857501
BRD-K73899643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26386
Perturb_9666_Mut_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.42672
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08573
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60798
arachidonic acid metabolism	KEGG Pathways	1.0	null
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K56820801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41686
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90535
KASUMI1	DepMap CRISPR Gene Dependency	1.0	4.80304
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDNRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1381
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
linoleate 9s-lipoxygenase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K93993903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2541
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96467
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84998
normal	GeneRIF Biological Term Annotations	1.0	null
BRD-K19237647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29745
BRD-K64073423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32309
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6497
Perturb_77_KD_MAP3K7/CHD1_SRP310152	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48502
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293694
membrane lipid metabolic process	GO Biological Process Annotations 2025	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.382
process	GeneRIF Biological Term Annotations	1.0	null
BRD-K32403186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45822
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
Prostate adenocarcinoma_PRAD_TCGA-CH-5788-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
ichthyosis	HPO Gene-Disease Associations	1.0	null
cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.462398
EHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23702
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09641
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06532
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07884
Peeling skin syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5395
Lagophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
Chondrodysplasia punctata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
BRD-K42964952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30522
TYKNU	DepMap CRISPR Gene Dependency	1.0	2.00722
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24981
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41054
AML193	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36177
BRD-K63030320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07483
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
Field CA1, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37847
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6229-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59415
BRD-K38046923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18301
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33626
periventricular stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27634
A549	CCLE Cell Line Gene CNV Profiles	1.0	1.36482
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
Epidermis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LTBR_INHIBITION - 1 Day_GDS2004_733_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857724
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833579
lipoxygenase pathway	GO Biological Process Annotations 2023	1.0	null
glutamate-cysteine ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.854
protein modification process	GO Biological Process Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849311
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1985
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02972
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2367
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UE-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	2.91846
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
BRD-K44265418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22222
BRD-K12312755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45741
Magnetosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
medial pallium (hippocampal allocortex)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03759
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75539
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77618
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07901
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06257
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10267
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40752
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.99952
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1158
LB771-HNC	GDSC Cell Line Gene Expression Profiles	1.0	1.58215
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-17p13_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989201
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.007
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23718
MSRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60459
Perturb_12909_KD_ESR1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58734
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46619
Perturb_8164_KD_TARDBP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.71379
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K63626200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23937
BRD-K28790383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17386
BRD-K18084996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40485
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68545
corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.40524
PMC9117466-NIHMS1784916-supplement-Supplementary_Tables_1_to_7.xlsx-Table_3-Supplementary_Table_3_HOXB13-repressed_genes_that_were_or_were_not_rescued_by_G84E_in_Fig_1a_HOXB13	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02519
long-chain fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
lipoxygenase3	GeneRIF Biological Term Annotations	1.0	null
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.146382
BRD-K72146456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05299
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22899
positive regulation of mucus secretion	GO Biological Process Annotations 2023	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04886
GSE85874_3_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_3619_KO_SMARCA4_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.74555
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.19655
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A901-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA	ChEA Transcription Factor Targets	1.0	null
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
monocarboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844315
ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K54510565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08702
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.02186
MSK-Leuk1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
BRD-K86964464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01328
BRD-K62547690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0794
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00815
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	3.23749
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.458231
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5583
CRCGN015_MCF10A_48H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.303
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04308
BRD-K43918582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2094
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15036
Glioblastoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.483206
abnormal epidermis stratum granulosum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K91615044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53888
palmoplantar keratoderma	HPO Gene-Disease Associations	1.0	null
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839347
abnormal epidermis stratum corneum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
critical	GeneRIF Biological Term Annotations	1.0	null
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
BRD-K03057797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09539
BRD-K53026281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20157
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00254
positive regulation of mucus secretion	GO Biological Process Annotations 2015	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU626	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81123
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2438
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81553
characterized	GeneRIF Biological Term Annotations	1.0	null
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621024
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07657
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37087
BRD-K75961186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10892
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61349
skin	GTEx Tissue Gene Expression Profiles	1.0	1.70713
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87133
abnormality of lower limb bone	HPO Gene-Disease Associations	1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44929
abnormality of skin adnexa	HPO Gene-Disease Associations	1.0	null
BRD-K41207293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06148
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.75
dorsal nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06751
Prostate adenocarcinoma_PRAD_TCGA-M7-A720-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
BRD-K16403365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09445
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09993
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37175
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79369
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63289
BRD-K45136330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07504
sphingolipid metabolic process	GO Biological Process Annotations 2025	1.0	null
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834757
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24657
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4635
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.939371
disease	GWASdb SNP-Disease Associations	1.0	0.033459
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34184
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.73
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84443
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02477
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20453
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.3555
RXF393	GDSC Cell Line Gene Expression Profiles	-1.0	-2.1492
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62574
Parasubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09892
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47963
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06942
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.66213
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968148
Esophageal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5701
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22541
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01628
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33942
BRD-K47098496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45066
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22394
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2023	1.0	null
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908508
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.8575
deficient	GeneRIF Biological Term Annotations	1.0	null
staining	GeneRIF Biological Term Annotations	1.0	null
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	5.42176
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46269
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
ILF2_02_88	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.70044
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Leukemia, Myeloid, Acute	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55321
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	1.20418
H2AL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51244
Bmi-1_KD_GDS2724_102_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K59130962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75636
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11083
NCIH524	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53204
BRD-K55800245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75212
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892142
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058804
BRD-K46195730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.567
Perturb_15505_KD_CDK7_SRP179971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1533
neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965933
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5832
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900104
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.64305
mantle zone of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34401
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07086
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4634
BRD-K32718856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00385
CTDSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21063
status	GeneRIF Biological Term Annotations	1.0	null
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85796
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17215
troxerutin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49659
Testicular Germ Cell Tumor	DisGeNET Gene-Disease Associations	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.08064
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.499
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971138
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.98514
dehydration	MGI Mouse Phenotype Associations 2023	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63012
CAKI1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54913
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62738
GSE198165,GSE198166_6_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
congenital nonbullous ichthyosiform erythroderma	HPO Gene-Disease Associations	1.0	null
REST_01_337	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60491
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6377
Secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.842
BRD-K75413392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21692
positive regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	1.0	1.14787
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866103
Lipoxygenase, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
muslim	GeneRIF Biological Term Annotations	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2869
pepstatin-4790	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EBF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53906
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15881
diffraction	GeneRIF Biological Term Annotations	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89379
ligand	GeneRIF Biological Term Annotations	1.0	null
strychnine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46074
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.059
BRD-K05886700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37605
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
BRD-K95359959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60228
BRD-K82868643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24645
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71452779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02099
preoptic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00815
pathways	GeneRIF Biological Term Annotations	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897592
BRD-K02329600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87941
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0441
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23734
FOXRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10385
Serotonergic synapse	KEGG Pathways 2026	1.0	null
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
BRD-K64970964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4707
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16438
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24901
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36418
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
regulation of MAPK cascade	GO Biological Process Annotations 2025	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18252
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75468
Perturb_7714_OE_IL25_SRP405857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.00762
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22876
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9895
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34925
J82	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69472
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.04194
CRCGN015_MCF10A_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15341
hair	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.985737
BRD-K77817104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22016
BRD-K92432769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1775
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8074
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K82909038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64632
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256702
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58153
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
BRD-K99833695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68474
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17475
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3716
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.056394
arachidonate 12-lipoxygenase activity	GO Molecular Function Annotations 2015	1.0	null
Pons, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29763
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07104
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16071
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55238630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82655
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932375
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69038251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01269
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
496100667_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18207
Gastrointestinal stromal tumor_Gastric Tissue_GSE15966	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.31264
mania	GWASdb SNP-Phenotype Associations	1.0	0.426693
pralidoxim	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23045
DMD_Deficiency_GDS2996_613_mouse_Cardiac muscles from 8-week (mdx animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC9314343-41467_2022_31892_MOESM8_ESM.xlsx-FigS7d-CTCF_in_promoter_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
protein lipidation	GO Biological Process Annotations 2015	1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
Perturb_7879_KD_EXOSC3_SRP266190	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.13997
Ichthyosiform Erythroderma, Congenital	DisGeNET Gene-Disease Associations	1.0	null
Oral squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
r4 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18137
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55628
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96361
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29851
linoleic acid metabolic process	GO Biological Process Annotations 2023	1.0	null
cox2	GeneRIF Biological Term Annotations	1.0	null
scales	GeneRIF Biological Term Annotations	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21561
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
BRD-K30236306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49798
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	0.856185
PMC9942993-pone.0281645.s002.xlsx-non-AR_as_all_as_gained-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00125
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840046
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09159
LS411N	CCLE Cell Line Gene Expression Profiles	1.0	1.48496
organic acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37527074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19063
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
Perturb_8276_KD_UPF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.4438
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09644
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.743993
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93948
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.036008
Meningeal Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40928
positive regulation of secretion	GO Biological Process Annotations 2015	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10347
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.848444
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.172041
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6032
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13211
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
Perturb_3976_KD_HIF1A_SRP057708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.30375
BRD-K81669067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36546
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4281
BRD-K61486072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07328
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993642
icSARA deltaORF6_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75879
preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02252
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07546
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17698
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K26704304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84248
BRD-K87461415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28931
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K29077209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25312
BRD-K20361257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33311
CLCN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44025
PMC9825391-41467_2022_35592_MOESM4_ESM.xlsx-MAF_Targeted_Seq_mutations-Unnamed_60_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_3530_KD_circCDKN2BAS1_SRP252917	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.12422
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.66102
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
X-linked ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.373
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.77528
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K99416393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23977
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44502
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16723
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
BRD-K85720719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73416
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18795
mantle zone of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48751
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22207
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92749
EVSAT	DepMap CRISPR Gene Dependency	1.0	8.03991
BRD-K25811799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08636
SNU1214	CCLE Cell Line Gene Expression Profiles	1.0	2.41089
Pruritus	DisGeNET Gene-Phenotype Associations	1.0	null
PMC3109859__F6	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K11823863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30868
Acrokeratosis verruciformis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16046
BRD-K82105033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42916
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.104
LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71376
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K41814083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02259
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45V-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14926
BRD-K91297952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86487
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71654
prerubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13468
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77024507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33869
epithelial ovarian cancer	GAD Gene-Disease Associations	1.0	null
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907371
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
establishment of skin barrier	GO Biological Process Annotations 2023	1.0	null
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03976
BRD-K50713036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27888
Mitochondrial crista	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168676_0_v_3_dach1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83534
t70-white-adipose_male_4w	MoTrPAC Rat Endurance Exercise Training	1.0	2.43533
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042379
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5072
Corneal Erosion	DisGeNET Gene-Disease Associations	1.0	null
Fibrosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.395
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	2.25771
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051835
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03126
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65071
BRD-K15930345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41044
Perturb_15431_KD_MED1_SRP179971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
Sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K56034970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25274
496100630_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10241
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54866
BRD-K00562490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16478
Larynx squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
Ichthyosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
epidermal thickening	HPO Gene-Disease Associations	1.0	null
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.346829
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09283
Conventional (Clear Cell) Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.26255
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980169
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of digit	HPO Gene-Disease Associations	1.0	null
abnormal skin appearance	MPO Gene-Phenotype Associations	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5737
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895027
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Rotavirus infection of children_Peripheral blood mononuclear cell_GSE2729	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.42458
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47901
linoleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38007
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.38029
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05402
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.8818
IM95	CCLE Cell Line Gene Expression Profiles	1.0	1.38686
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7452
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26704
BRD-K54478142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01553
BRD-K26852477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05099
Ammon's horn	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22651
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.601
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29762
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16334
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08455
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0626
abnormal epidermal layer morphology	MPO Gene-Phenotype Associations	1.0	null
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the eyebrow	HPO Gene-Disease Associations	1.0	null
presubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11438
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191648
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02589
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999534
BRD-K47326075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78332
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32401
Autosomal recessive congenital ichthyosis 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
body mass index	GAD Gene-Disease Associations	1.0	null
Keratosis follicularis spinulosa decalvans	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
NMRAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43471
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927761
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68530167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28958
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59347
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00923
carboxylic acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
CRCGN017_MCF10A.TP53.M_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21815
intermediate part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95626
Hailey-Hailey disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
BRD-K90103010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62281
dehydration	HPO Gene-Disease Associations	1.0	null
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45851
Perturb_2120_KD_DDX5_SRP276651	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.83462
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74031
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84558
inflammatory abnormality of the eye	HPO Gene-Disease Associations	1.0	null
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7462
abnormality of toe	HPO Gene-Disease Associations	1.0	null
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
BRD-K61354849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37171
MXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40061
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87188
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910118
BRD-K18149487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51516
LMAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57896
layer 3 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55242
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886694
Metabolism	Reactome Pathways 2014	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
GSE85874_4_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78677
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04684
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04355
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.62675
PMC10920960-mmc3.pdf-0-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92403
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K14124956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4622
sphingolipid biosynthetic process	GO Biological Process Annotations 2023	1.0	null
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3687
15067324-Table3S	GeneSigDB Published Gene Signatures	1.0	null
ceramide metabolic process	GO Biological Process Annotations 2025	1.0	null
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23365
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76875
BRD-K32475622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29383
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051927
Carcinoma, Cribriform	DisGeNET Gene-Disease Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24502
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.912705
hsa-miR-129-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
hearing abnormality	HPO Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9758
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46152
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.12287
PPARA_Deficiency_GDS2934_632_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
IL23-mediated signaling events	PID Pathways	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.96857
PMC9195629-Table1.xlsx-Supplementary_Table_1-C-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2722-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47410882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74394
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
impaired skin barrier function	MGI Mouse Phenotype Associations 2023	1.0	null
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844315
epidermal cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21935
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2143
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944309
KE39	DepMap CRISPR Gene Dependency	1.0	3.24127
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56412
Perturb_8157_KD_GPKOW_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.04
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61322
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
ESS1	DepMap CRISPR Gene Dependency	1.0	3.61574
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34991
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883245
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83623
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8696
BRD-K75074041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04905
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20088
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.89528
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27656
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.007
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900733
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98904
CORL311	CCLE Cell Line Gene Expression Profiles	1.0	1.53065
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43279
organonitrogen compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
QRICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06637
platelet-type bleeding disorder 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
SAGA-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.723
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2012
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60613
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34311
BRD-K74641261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27072
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107635
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hyperkeratosis	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K24565713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05464
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6282
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.631
r9 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27782
deafness-intellectual disability, Martin-Probst type syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.569
r4 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2896
BRD-K26720280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00844
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.686
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857708
abnormal skin condition	MPO Gene-Phenotype Associations	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054786
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.217
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.364603
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01206
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26184956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02525
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.20481
Refsum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43241
ichthyosis, congenital, autosomal recessive 2	OMIM Gene-Disease Associations	1.0	null
BRD-K94580242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39914
abnormality of the head	HPO Gene-Disease Associations	1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31647
abnormality of the pinna	HPO Gene-Disease Associations	1.0	null
BRD-K18629365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35642
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.236683
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48789
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
UACC-893	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17094
Regular astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13055
BRD-K11741103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22416
BRD-K53088255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13192
striatum (corpus striatum)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31025
BRD-K78477132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40395
BRD-K80921954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23846
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.08231
Perturb_8444_KD_IGF2BP1_SRP151057	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.58682
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89235
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23062
covers	GeneRIF Biological Term Annotations	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10846
KMS11	DepMap CRISPR Gene Dependency	1.0	2.88678
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	1.60765
CALU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968148
Perturb_9080_KD_FGFRL1_SRP319532	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.3204
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30909
PMC10328386-DataSheet_1.pdf-0-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1774
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3413
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87042
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
resulted	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17886
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.393061
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22839
PMC12867126-NIHMS2139346-supplement-Supplementary_Table_S1.pdf-46-ZNF410_ZNF410	Rummagene Transcription Factor Associations 2026	1.0	null
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.63119
BRD-K44861255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38663
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45139
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.600747
Skin stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63415
GATA3	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16071
prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07256
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51307
PMC12592558-41419_2025_8097_MOESM4_ESM.xlsx-downregulated_3_-_DATASET_1-RNA_Seq_analysis_upon_lncMB3_KD_in_D283_Med_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12575
Perturb_9667_KO_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.63344
synthaselinked	GeneRIF Biological Term Annotations	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29157
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08069
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854115
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23975
FLI1	ChEA Transcription Factor Targets	1.0	null
EEIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86131
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76482408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50212
BRD-K71005143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45344
BRD-A43330902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58392
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23911
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.827097
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7906601-elife-62470-supp4.xlsx-Table_S7_MS_and_siRNA_KD-Supplementary_File_4_Summary_of_HIV-1_splice_variant_interactome_MS_data_and_siRNA_KD_expression_changes_data_Related_to_Figures_2_and_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.978197
developed	GeneRIF Biological Term Annotations	1.0	null
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23958
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48619
COPG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61573
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A14183911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49295
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.877049
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.382
CFTR_Deficiency_GDS1843_191_mouse_Lungs - Animals examined at 3 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58569
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cause	GeneRIF Biological Term Annotations	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.227214
gangrene	HPO Gene-Disease Associations	1.0	null
BRD-K85912419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11734
Myocardial Infarction	HuGE Navigator Gene-Phenotype Associations	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1942
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.049
Field CA1, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6272
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.09561
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
BRD-K52354895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20553
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15924535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02679
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-338-SOX15_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
short toe	HPO Gene-Disease Associations	1.0	null
Epidermolytic hyperkeratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.984
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54608
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	1.46657
atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.237216
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
loxdependent	GeneRIF Biological Term Annotations	1.0	null
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GNG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03775
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.960482
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
15640797-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CRCGN008_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10345
single-organism process	GO Biological Process Annotations 2015	1.0	null
WA-15-KX40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249643
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56473
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.173
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65391
BRD-K76350099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05349
SP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93315
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4158
BRD-K55835264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.652
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.024
abnormality of fluid regulation	HPO Gene-Disease Associations	1.0	null
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
increased body weight	GWASdb SNP-Phenotype Associations	1.0	0.598473
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62276
AIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14429
Subiculum, dorsal part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78894
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3447
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
leading	GeneRIF Biological Term Annotations	1.0	null
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08703
BRD-K97263385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43838
GSE101112_0_v_2_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ectropion	DisGeNET Gene-Disease Associations	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242174
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904433
Prostate adenocarcinoma_PRAD_TCGA-KK-A8II-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27709
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01397
BRD-K69171646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21502
barrier	GeneRIF Biological Term Annotations	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1545
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tgm1	GeneRIF Biological Term Annotations	1.0	null
NAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5844
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.9541
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855637
NB13	GDSC Cell Line Gene Expression Profiles	-1.0	-2.12145
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal epidermis stratum corneum morphology	MPO Gene-Phenotype Associations	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
breast cancer	GAD Gene-Disease Associations	1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96335
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.63152
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65549
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
PMC8566473-41467_2021_26653_MOESM3_ESM.xlsx-SOX2_interacting_proteins-Gene_symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8339_OE_MSI1_SRP219036	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.958
abnormality of the periorbital region	HPO Gene-Disease Associations	1.0	null
BRD-K87617154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00813
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.154036
SMC3	ENCODE Transcription Factor Targets	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34059
Brain Lower Grade Glioma_LGG_TCGA-HT-8105-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37803976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86693
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dry skin	MGI Mouse Phenotype Associations 2023	1.0	null
aminoacyl-tRNA synthetase multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1626
Body Composition	dbGAP Gene-Trait Associations	1.0	0.076603
times	GeneRIF Biological Term Annotations	1.0	null
abnormality of lower lip	HPO Gene-Disease Associations	1.0	null
Metabolism	Reactome Pathways 2024	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.11794
BRD-K07035171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22426
BRD-K64299311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60684
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21729626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51038
BRD-K92579151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31553
FOXP1	ChEA Transcription Factor Targets	1.0	null
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
BRD-K90527476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4131
Dry Skin	DisGeNET Gene-Phenotype Associations	1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9141
EGR-1_KO_GDS3607_525_mouse_Retina - 30 Days (POST-NATAL)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07344
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15514
H2795	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
Striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32218
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38972
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90153
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20453
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.27936
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855637
erythroderma	GeneRIF Biological Term Annotations	1.0	null
BRD-K46620987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21686
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.858416
chromosome	GeneRIF Biological Term Annotations	1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
represent	GeneRIF Biological Term Annotations	1.0	null
abnormality of the cornea	HPO Gene-Disease Associations	1.0	null
Perturb_7390_KO|KD_UPF3A_ERP130415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.1579
ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.138716
PSMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61534
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911146
TRPV4_DEPLETION_GDS4851_89_mouse_3T3-F442A adipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
protein lipidation	GO Biological Process Annotations 2023	1.0	null
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8124_KD_CCAR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.39379
B-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_3910_KO_ARID1A_ERP114370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.42771
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
Ichthyosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17717
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05402
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19389825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87521
Perturb_522_KD_MAVS/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34173
Gangrene	DisGeNET Gene-Disease Associations	1.0	null
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38119
BRD-K67896259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2834
ectropion	HPO Gene-Disease Associations	1.0	null
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22831
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9240646__F7	PFOCR Pathway Figure Associations 2024	1.0	null
Lipoxygenase, mammalian	InterPro Predicted Protein Domain Annotations	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50551
5-lipoxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.281
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09277
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85007
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.25409
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7701
neurodevelopmental abnormality	HPO Gene-Disease Associations	1.0	null
formation	GeneRIF Biological Term Annotations	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.853116
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83589
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
sphingolipid metabolic process	GO Biological Process Annotations 2023	1.0	null
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
LCLC-97TM1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.40881
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
paralysis	HPO Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
shiny skin	MPO Gene-Phenotype Associations	1.0	null
BRD-K44834268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52835
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03188
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.059
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.529
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6893
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70895
BRD-K79735667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02523
homeostatic process	GO Biological Process Annotations 2015	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62574
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69938
Lipoxygenase, iron binding site	InterPro Predicted Protein Domain Annotations	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05402
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21402
BRD-K08043579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29972
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60238606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.334
CA-46 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
PPARA_agonist activation_GSE17250_475_mouse_Isolated hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23718
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40876
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7644-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55094
Subiculum, ventral part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09225
FABP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2741
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.25464
Keratohyalin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.106
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.56923
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38615
MSTO211H	DepMap CRISPR Gene Dependency	1.0	2.34354
molecular layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62313
DAZAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36448
generalized abnormality of skin	HPO Gene-Disease Associations	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lipoxygenases	GeneRIF Biological Term Annotations	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061534
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22904
MIST1_KO_GDS1731_758_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
oa1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
KASUMI6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34626
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48893
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40477
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35428
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17575
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19673
r5 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28604
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14326
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989039
BRD-K85395981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41964
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.653
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041534
Perturb_8158_KD_HNRNPLL_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Coronary Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.059
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16904
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954237
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05207
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
Perturb_8162_KD_SNRNP70_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98298
BRD-K04695511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33167
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25527
BRD-K76420749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96463
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17009876-tableS1a	GeneSigDB Published Gene Signatures	1.0	null
Reticulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.44
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16872
BRD-K25907192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37649
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59825
A-431 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
Perturb_10121_KO_NGLY1_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.84016
LTBR_INHIBITION - 3 Day_GDS2004_735_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
nuclear	GeneRIF Biological Term Annotations	1.0	null
unsaturated fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29962
Epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.274
KCTD20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57059
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37175
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912075
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31779
PL4	DepMap CRISPR Gene Dependency	1.0	2.60386
BRD-K05246869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47587
BRD-K22420708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01473
BRD-K34169251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12262
Perturb_15515_KD_E2F2_SRP314859	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.52024
BRD-K53639581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10604
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057328
CRCGN017_MCF10A.WT.HP_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2209
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55069
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05694
Perturb_478_KD_PPARGC1A_SRP278736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.15064
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26012
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ferroxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
impaired skin barrier function	MPO Gene-Phenotype Associations	1.0	null
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null