association dataset threshold value standardized value layer 6b of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.035 molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86458 TCFCP2L1-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37766 burkitt lymphoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.62385 Cortical microtubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.625 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903697 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.981165 Posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24767 Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80056 lymphoid tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.073897 superficial stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89365 GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.83297 MPI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32755 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15938 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dermal papilla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.935 mantle zone of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08038 PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WVLH-0011-R5A-SM-3MJFW GTEx Tissue Sample Gene Expression Profiles 1.0 0.886602 hsa-miR-24 TargetScan Predicted Conserved microRNA Targets 1.0 0.265648 EBF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2559 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02258 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ChIP_SUZ12_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Condensin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.839 BRCA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02297 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.82549 NZOV9 DepMap CRISPR Gene Dependency 1.0 5.19112 H3K27me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 0.872492 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.21709 CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53858 GTEX-N7MT-0011-R10A-SM-2I3E1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13823 Caveolar macromolecular signaling complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.703 ALL-PO COSMIC Cell Line Gene Mutation Profiles 1.0 null Purkinje cell layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01156 UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34514 CYB561 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84918 RELA JASPAR Predicted Transcription Factor Targets 1.0 null KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61778 respiratory mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.533065 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amer GeneRIF Biological Term Annotations 1.0 null HOXD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61483 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4327 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AMOTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01355 GTEX-T6MN-0011-R6A-SM-32QP8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.919291 LRRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04695 head of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.31557 specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.463905 PCSK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31487 primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02917 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87013 MPLKIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94046 hsa-miR-202 TargetScan Predicted Conserved microRNA Targets 1.0 0.062888 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.93814 METTL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3098 amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868706 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15268 GSE214382,GSE214383_6_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null PCI38 DepMap CRISPR Gene Dependency 1.0 6.14574 dorsolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.971073 AMER1 Pathway Commons Protein-Protein Interactions 1.0 null MED13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47851 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904657 PCNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43415 Medial habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14201 VZ in caudal cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.844649 SMAD4-21741376-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.987088 BRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37721 respiratory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.243605 SESTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80054 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.41926 hsa-miR-4322 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28485 cerebralcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07384 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0323 APC Pathway Commons Protein-Protein Interactions 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 SIRT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1998 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.888949 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null anterior digastric muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.01887 IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30704 MOCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66678 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null jf1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.721 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MutLbeta complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.82 Simple lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5051 NCI-H1435 COSMIC Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.70022 AKAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82477 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44964 GSE195559_2_v_7_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null METTL18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23139 dorsolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04642 GSE112962,GSE112963_2_v_1_ddx5_human RummaGEO Gene Perturbation Signatures 1.0 null AMIGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08253 C8orf33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53003 wnt signaling pathway GO Biological Process Annotations 2015 1.0 null GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 1.07543 GSE157555,GSE157556_0_v_1_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH2106 CCLE Cell Line Gene CNV Profiles -1.0 -1.4598 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26712 MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL4W-0011-R6a-SM-2I3GA GTEx Tissue Sample Gene Expression Profiles 1.0 0.900019 Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29326 TP63 ChEA Transcription Factor Targets 1.0 null PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-2926-SM-32PKC GTEx Tissue Sample Gene Expression Profiles 1.0 1.03949 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null GTEX-TSE9-0011-R10A-SM-3DB7O GTEx Tissue Sample Gene Expression Profiles 1.0 1.05327 CAMKK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2776 habenula (old epithalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22425 GTEX-RVPV-0011-R5A-SM-2TF69 GTEx Tissue Sample Gene Expression Profiles 1.0 0.851849 Sex chromatin COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.925 wnt GeneRIF Biological Term Annotations 1.0 null GSE195743_3_v_2_lhx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null CAPAN-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_iPS-15b Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC6855629-pone.0225186.s003.xlsx-Sheet1-DEGs_repressed_by_MEIS1_in_human_cell_lines_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4500 TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 NRIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94459 GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28715 B4GALNT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94054 GTEX-WHSE-0011-R1A-SM-3P5ZK GTEx Tissue Sample Gene Expression Profiles 1.0 1.02834 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24166 JHOC5 CCLE Cell Line Gene CNV Profiles 1.0 1.94123 EFM-19 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIMA CCLE Cell Line Gene Expression Profiles 1.0 1.91221 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.950718 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.03665 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HMOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95412 POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A ENCODE Transcription Factor Targets 1.0 null SLC11A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49003 primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.84045 REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVUS-0011-R10A-SM-3GIK3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.908211 JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.09177 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARHGEF10L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9888 JHOC5 CCLE Cell Line Gene Expression Profiles -1.0 -1.746 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMSB4X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83614 H2BK15ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19184 LN-229 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.581 regulation of Wnt signaling pathway GO Biological Process Annotations 2023 1.0 null MutSgamma complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.83 tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Unnamed_4_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null TP53I3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10307 GTEX-X261-0011-R10B-SM-4E3JT GTEx Tissue Sample Gene Expression Profiles 1.0 0.972874 HDAC1 ENCODE Transcription Factor Targets 1.0 null MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-3944-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02747 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-T5JC-0011-R7A-SM-32PME GTEx Tissue Sample Gene Expression Profiles 1.0 0.848853 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13154 central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.876225 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0844 mantle zone of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.8834 OAW42 DepMap CRISPR Gene Dependency 1.0 3.73085 MET CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98701 GTEX-XLM4-0011-R7A-SM-4AT5L GTEx Tissue Sample Gene Expression Profiles 1.0 0.958506 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.84168 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.63983 GSE148096_1_v_0_erlotinib_human RummaGEO Drug Perturbation Signatures -1.0 null NCIH209 CCLE Cell Line Gene CNV Profiles -1.0 -1.38142 knockdown GeneRIF Biological Term Annotations 1.0 null H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.32422 Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF816 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.2165 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05871 GSE214382,GSE214383_5_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-N7MT-0011-R6a-SM-2I3G3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.986523 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.860406 Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03448 cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.958111 GTEX-UTHO-0011-R6A-SM-3GIJW GTEx Tissue Sample Gene Expression Profiles 1.0 0.857018 LMSU CCLE Cell Line Gene Expression Profiles -1.0 -2.76794 TRIM54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7385 Ventral posteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.63614 EP300 ENCODE Transcription Factor Targets 1.0 null GTEX-RNOR-0011-R7A-SM-2TF4V GTEx Tissue Sample Gene Expression Profiles 1.0 1.04191 H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intermediate stratum of JcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05492 HDAC2 ENCODE Transcription Factor Targets 1.0 null ZNF256 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54893 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.50837 G402 CCLE Cell Line Gene CNV Profiles 1.0 1.61929 GSE239688_2_v_3_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH1436 CCLE Cell Line Gene Expression Profiles 1.0 1.60634 KOSC-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE151829,GSE151831_5_v_8_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null MXI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.24138 CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DSCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76809 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.0114 TSR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8845 anchoring junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.111848 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.963702 posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.99302 KATOIII CCLE Cell Line Gene CNV Profiles -1.0 -1.49028 GSE135350_3_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null Rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23954 reduces GeneRIF Biological Term Annotations 1.0 null hsa-miR-4458 TargetScan Predicted Conserved microRNA Targets 1.0 0.389112 GSE119498_2_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062492 hsa-miR-3675-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 JHOM2B CCLE Cell Line Gene Expression Profiles -1.0 -3.07772 focal adhesion COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.173003 r3 part of magnocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1053 VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44551 REST_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null reticular nucleus of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27649 rostral division of VL Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03175 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09586 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-N7MS-0011-R1a-SM-2HMJG GTEx Tissue Sample Gene Expression Profiles 1.0 1.02368 brain GTEx Tissue Gene Expression Profiles 1.0 1.45239 GTEX-NL4W-0011-R10A-SM-2I3DY GTEx Tissue Sample Gene Expression Profiles 1.0 0.927132 cerebellar cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.22592 FHIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29821 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.91806 A427 COSMIC Cell Line Gene Mutation Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.951774 hsa-let-7g TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 GTEX-R55F-0011-R6A-SM-2TF4L GTEx Tissue Sample Gene Expression Profiles 1.0 0.971219 HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null temporotympanic muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68557 REST_Panc1_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null REST_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dentate gyrus, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85618 HELA COSMIC Cell Line Gene Mutation Profiles 1.0 null TDRD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96176 ONECUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76787 PSMB5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64333 red nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23722 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TCCSUP CCLE Cell Line Gene Expression Profiles -1.0 -1.74742 BEN CCLE Cell Line Gene Expression Profiles 1.0 1.82779 Medial geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06369 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.78331 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05203 Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21997 GTEX-R55E-0011-R11A-SM-2TC6I GTEx Tissue Sample Gene Expression Profiles 1.0 2.09823 UBQLN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80959 SP in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.944118 RC3H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55941 DQX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37902 Colon muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.706 intermediate stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22791 Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nose TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.561245 H3K27me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null superficial stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55737 regulation of canonical Wnt signaling pathway GO Biological Process Annotations 2025 1.0 null m2 part of pararubral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13754 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830333 GSE130081,GSE130082_0_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE234289_5_v_0_rfx6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null substantia nigra, pars reticulata, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.57951 PMC7782476-41467_2020_20434_MOESM7_ESM.xlsx-KLF14_string_interactions-node1_KLF14 Rummagene Transcription Factor Associations 2026 1.0 null PTEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77463 hsa-miR-4722-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null Perisynaptic extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.999 CTBP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.91974 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040755 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.21654 TAF1_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LYSP100-associated nuclear domain COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.071 VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.0803 posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3825 GTEX-T2IS-0011-R6A-SM-32QP2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.853086 Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phosphatidylinositol bisphosphate binding GO Molecular Function Annotations 2023 1.0 null GSE98898_7_v_1_hoxa1_human RummaGEO Gene Perturbation Signatures 1.0 null M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.25283 MYC ENCODE Transcription Factor Targets 1.0 null GTEX-T6MN-0011-R11A-SM-32QOX GTEx Tissue Sample Gene Expression Profiles 1.0 1.68683 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.19337 inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.840637 AMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85796 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20657 GTEX-XOTO-3026-SM-4B65M GTEx Tissue Sample Gene Expression Profiles 1.0 1.19679 CTTNBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76967 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28495 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.878305 C15orf61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95299 ZFP30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.12362 RFX5 ENCODE Transcription Factor Targets 1.0 null WRNIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02755 PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null IPC-298 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205163,GSE205164_5_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null Lobule II, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14233 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.60595 olfactory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.671692 SUZ12-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null FBXO17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28256 ELF1 ENCODE Transcription Factor Targets 1.0 null CCK-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null ADAMTS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25943 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.72778 GCIY COSMIC Cell Line Gene Mutation Profiles 1.0 null NME4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75133 GSE157555,GSE157556_4_v_2_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null RP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53666 E2F6 ENCODE Transcription Factor Targets 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32829 FAM124A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67868 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null RCCFG2 DepMap CRISPR Gene Dependency 1.0 5.02487 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12677 Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48274 GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 0.984587 496100346_FWM_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.28936 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46597 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ESRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62265 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TOMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55319 BB30HNC DepMap CRISPR Gene Dependency 1.0 3.04204 KLF4 ChEA Transcription Factor Targets 1.0 null hsa-miR-4487 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3B-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MAZ_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE132694,GSE132717_0_v_2_meis1_human RummaGEO Gene Perturbation Signatures -1.0 null TFCP2L1 ChEA Transcription Factor Targets 1.0 null Pedunculopontine nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00476 GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles 1.0 1.12153 hsa-miR-4667-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.212286 496100278_FWM_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.19548 periventricular stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01369 CHST10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60999 stomach HPA Tissue Gene Expression Profiles 1.0 0.948627 BmN cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.584 superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44792 REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nephroblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.16 FFAR4_KO_GDS4811_507_mouse_adipose GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-T2IS-0011-R3A-SM-32QPB GTEx Tissue Sample Gene Expression Profiles 1.0 1.06844 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.38993 GSE153836_11_v_2_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11423 GTEX-T5JC-0011-R8A-SM-32PLM GTEx Tissue Sample Gene Expression Profiles 1.0 1.06959 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null Copula pyramidis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04218 RBBP5 ENCODE Transcription Factor Targets 1.0 null outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20288 NSMAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70665 Acute Myeloid Leukemia_LAML_TCGA-AB-2844-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRERF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.673 GTEX-Q2AG-0011-R1A-SM-2HMJI GTEx Tissue Sample Gene Expression Profiles 1.0 0.868581 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.27821 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.119 IRF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2478 hsa-miR-3913-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.81367 VAL COSMIC Cell Line Gene Mutation Profiles 1.0 null SELENOF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24268 USP16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21003 ZNF570 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58983 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CAL-12T COSMIC Cell Line Gene Mutation Profiles 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.64906 GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 1.53108 cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null m1Lim part of the midbrain reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04701 COR-L321 COSMIC Cell Line Gene Mutation Profiles 1.0 null r7 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40503 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.0701 hippocampus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lymphoid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.108821 ZNF292 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28047 REST_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33699 TCF4 ChEA Transcription Factor Targets 1.0 null HMGCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81585 RAPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89707 periventricular stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24694 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ7-2726-SM-2I3FT GTEx Tissue Sample Gene Expression Profiles 1.0 1.07574 ZNF514 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.969 hsa-let-7d TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 SH2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55 hsa-miR-4282 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SETDB1 ChEA Transcription Factor Targets 1.0 null Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.9373 EDNRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1381 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47528 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE111660_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040587 GTEX-N7MS-0011-R6a-SM-2HMJ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18245 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22911 CCNK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74991 CALM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98828 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3365 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_6_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.219 REST-18959480-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.986759 NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-7637-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27041 AKT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86097 Acute Myeloid Leukemia_LAML_TCGA-AB-2851-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7782476-41467_2020_20434_MOESM7_ESM.xlsx-KLF14_string_interactions-node2_KLF14 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-1301 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 QIMR-WIL COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-3927 TargetScan Predicted Conserved microRNA Targets 1.0 0.078844 H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZEB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05939 Large_Intestine-intestinal enteroendocrine cell Tabula Sapiens Gene-Cell Associations 1.0 0.0 Vermal regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12055 PPARA_agonist activation_GSE17251_474_human_Isolated hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE166944_3_v_2_eif4b_mouse RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32367 ZBED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40533 IRAK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12919 TAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59862 NAP1L5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5976 GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.7775 KASUMI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37935 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE116930,GSE116935_3_v_0_hes7_human RummaGEO Gene Perturbation Signatures 1.0 null MGAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80514 PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Gene_Name_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-UTHO-0011-R5A-SM-3GIJD GTEx Tissue Sample Gene Expression Profiles 1.0 0.934306 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10075 NOVA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99918 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PKM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85478 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17854 PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Nearest_Ensembl_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07766 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null NCIH1385 CCLE Cell Line Gene Expression Profiles 1.0 1.71654 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-NL3H-0011-R6a-SM-2I3G8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08279 TAGLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74889 FOXO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09267 GTEX-X261-0011-R8A-SM-4E3I5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.893935 BMPR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71505 GTEX-Q2AG-0011-R11A-SM-2HMKZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.06627 SIN3A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ADRA2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34595 H3K36me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null WDR18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90108 Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26619 CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95296 SUZ12 ChEA Transcription Factor Targets 1.0 null H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZFP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91196 SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPRYD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45485 GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.60513 GOLGA6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38285 TEX45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14495 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.881753 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.92822 GSE164505,GSE164506_3_v_2_indisulam_human RummaGEO Drug Perturbation Signatures -1.0 null PAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9873 ARMCX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7084 MAPK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4306 NEUROG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44755 TATDN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30294 FOXP1-21924763-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XX-0011-R10B-SM-46MWO GTEx Tissue Sample Gene Expression Profiles 1.0 1.33449 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0891 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06861 SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.56496 Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary motor area, Layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19924 hippocampus (hippocampal formation)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.857365 P3H4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73438 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ACSM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81546 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NBDY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31018 COLO680N CCLE Cell Line Gene CNV Profiles 1.0 1.65117 FIBIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2134 superficial stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19434 GTEX-NPJ7-0011-R8a-SM-2I3G2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14148 PDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00675 EW1 DepMap CRISPR Gene Dependency 1.0 2.78512 CEBPD ENCODE Transcription Factor Targets 1.0 null inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06207 GCLM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49046 RREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 121.273 posterior triangular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2351 GSE124932_2_v_1_sarm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE261563_9_v_1_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03962 ZMYM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33856 intermediate stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72546 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10131 SDHAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79703 mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.55713 Perturb_5678_KO_Pgr_ERP140354 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 VSX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25278 ZBTB38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83218 GTEX-WWYW-0011-R11A-SM-3NB38 GTEx Tissue Sample Gene Expression Profiles 1.0 1.64805 RADX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30539 AHRR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96819 NUS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56068 mediodorsal nucleus of thalamus_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.56109 FAM169A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18502 THAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6352 lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25504 REST_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-0011-R8A-SM-4E3II GTEx Tissue Sample Gene Expression Profiles 1.0 1.13761 TMEM138 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18894 GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles 1.0 1.93897 496100596_FWM_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.55771 NAP1L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13119 SPIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91915 SMIM12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11463 GSR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09111 PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-177-SP2_SP2 Rummagene Transcription Factor Associations 2026 1.0 null cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.885303 amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.914343 REST_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MS751 DepMap CRISPR Gene Dependency 1.0 2.82954 GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 1.04809 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null GSE133764_2_v_0_chd2_human RummaGEO Gene Perturbation Signatures -1.0 null pterigoid muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17354 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-2426-SM-3NMDB GTEx Tissue Sample Gene Expression Profiles 1.0 1.28852 GTEX-S7SE-0011-R8A-SM-2XCDG GTEx Tissue Sample Gene Expression Profiles 1.0 1.19049 GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.910717 inner SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911852 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059099 H1-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72244 H3K27me3_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEC6 DepMap CRISPR Gene Dependency 1.0 4.14353 SUPM2 DepMap CRISPR Gene Dependency 1.0 2.127 GSE179002_3_v_1_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-4796-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.913195 cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044619 Cerebellum TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.30479 NCIH2452 DepMap CRISPR Gene Dependency 1.0 2.37335 GTEX-N7MT-0011-R5a-SM-2I3G6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.956115 GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 1.92795 IL17RD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15266 GSE155031_5_v_1_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.66354 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.963702 WWC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67985 GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.10024 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR3-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE130715_2_v_3_budesonide_human RummaGEO Drug Perturbation Signatures -1.0 null TCEA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70216 SKMG1 DepMap CRISPR Gene Dependency 1.0 2.00796 hsa-let-7b TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.869714 Uterine Carcinosarcoma_UCS_TCGA-NF-A4WX-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.082 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057536 NME6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90787 Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34665 superficial stratum of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89824 ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7457 RPRD1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72365 GTEX-WHSE-0011-R6A-SM-3P5ZP GTEx Tissue Sample Gene Expression Profiles 1.0 0.874321 GSE122990,GSE123061_0_v_1_urod_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTSL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23393 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBL1XR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46647 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.44006 FGFR3_KD_GDS4454_79_human_RT112 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE119498_0_v_7_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null Uvula (IX), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06046 SNU475 CCLE Cell Line Gene Expression Profiles -1.0 -1.61099 MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1059 MEGF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74536 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07969 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.989524 GTEX-QVJO-0011-R4A-SM-2S1QL GTEx Tissue Sample Gene Expression Profiles 1.0 0.889785 ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5717 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06306 AXIN2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IFFO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65541 EFO-27 COSMIC Cell Line Gene Mutation Profiles 1.0 null UPCISCC131 DepMap CRISPR Gene Dependency 1.0 2.8541 cortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.958969 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles 1.0 1.18066 lymphoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.265725 PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3 Rummagene Transcription Factor Associations 2026 1.0 null SRF JASPAR Predicted Transcription Factor Targets 1.0 null intermediate stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19854 Meiotic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.979 JEG3 DepMap CRISPR Gene Dependency 1.0 3.0216 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85469 SNU398 DepMap CRISPR Gene Dependency 1.0 2.06888 Neurodegeneration with brain iron accumulation 5 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.438 dorsolateral prefrontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.848119 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.828644 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles 1.0 1.81921 synapse-associated extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.998 SEMA4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23244 Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100608_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.22403 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NECTIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50243 Brain Lower Grade Glioma_LGG_TCGA-S9-A6UB-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.913498 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.17368 III, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.95235 FOXP2_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE92457_9_v_10_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-Q2AG-0011-R6A-SM-2HML7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02818 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.922731 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 hsa-miR-3545-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PPP1R16B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00698 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13929 G0S2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30907 globus pallidus, external segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32611 dorsolateral prefrontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11178 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.19517 hsa-miR-4650-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.039622 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.47895 ILVBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04153 GSE142684_3_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216274,GSE216292_4_v_2_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.57636 periventricular stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67639 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.959089 ALX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60578 ALDH3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73839 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.854946 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22321 DMS53 CCLE Cell Line Gene CNV Profiles -1.0 -2.59482 COX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29694 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AG-0011-R5A-SM-2HMJH GTEx Tissue Sample Gene Expression Profiles 1.0 0.991753 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QMR6-0011-R6A-SM-32PKP GTEx Tissue Sample Gene Expression Profiles 1.0 1.07792 mRNA_EOMES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE113734_3_v_0_qprt_human RummaGEO Gene Perturbation Signatures -1.0 null Lobule III, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16009 regulation of biological process GO Biological Process Annotations 2015 1.0 null UCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92284 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10971 SKMEL28 CCLE Cell Line Gene Expression Profiles -1.0 -1.53156 GSE239844_6_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null HDX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58127 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09973 GLI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42927 nonredundant GeneRIF Biological Term Annotations 1.0 null ventral juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05433 BOK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95923 SHARPIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50295 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4763 GSE133087_5_v_0_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null Nrf2_deficiency_GDS3406_156_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney - Medulla GTEx Tissue Gene Expression Profiles 2023 1.0 4.87758 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070982 Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69133 Sarcoma_SARC_TCGA-PC-A5DK-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21345 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.421765 VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.974082 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null UBE2G1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.04511 HLFA CCLE Cell Line Gene Expression Profiles -1.0 -2.0607 GTEX-WWYW-3126-SM-3NB39 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20736 TAF1 ENCODE Transcription Factor Targets 1.0 null CREB1 JASPAR Predicted Transcription Factor Targets 1.0 null mantle zone of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02006 inhibit GeneRIF Biological Term Annotations 1.0 null TGIF2LY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75684 r2 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95559 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-WL46-0011-R6A-SM-3LK6X GTEx Tissue Sample Gene Expression Profiles 1.0 0.828094 GSE142684_2_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null GRB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63242 Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19564 amygdaloid complex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.844219 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28495 GTEX-OHPN-0011-R5A-SM-2I5FF GTEx Tissue Sample Gene Expression Profiles 1.0 0.91458 EEF1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2911 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.26019 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.990985 GTEX-WVLH-0011-R2A-SM-3MJFJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.14462 JHUEM3 CCLE Cell Line Gene Expression Profiles -1.0 -2.25042 VZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.43435 GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.73952 Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82946 GTEX-T5JC-2326-SM-32PMR GTEx Tissue Sample Gene Expression Profiles 1.0 1.63971 ASCL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82826 GTEX-NL4W-0011-R11A-SM-2I3DW GTEx Tissue Sample Gene Expression Profiles 1.0 2.18381 SLC37A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37905 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Pachytene cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.641 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.12039 REC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.48984 GTEX-QDT8-0011-R3A-SM-32PKR GTEx Tissue Sample Gene Expression Profiles 1.0 0.892072 BL70 CCLE Cell Line Gene CNV Profiles -1.0 -1.66195 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36147 Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29315 INTS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6004 Brain stem TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TBX15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91655 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74546 GTEX-WHSE-0011-R7A-SM-3P5YZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.936354 WNK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26365 GSE205163,GSE205164_3_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null TIMM21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44181 GSE119498_0_v_10_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3670 TargetScan Predicted Conserved microRNA Targets 1.0 0.181316 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66322 primary auditory cortex (core)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.76242 H3K27me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DOT1L_DELETION_GDS4295_428_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 7 days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null WASL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22997 GYG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83873 plasma membrane GO Cellular Component Annotations 2015 1.0 null TUR COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GNRH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66869 NLGN4Y CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78852 CLPSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61877 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPM1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89321 MutLgamma complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.749 GTEX-UTHO-0011-R3A-SM-3GIK8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.853182 TBX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29233 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31056 amygdaloid complex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.964696 RECQL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52703 GSE149096_4_v_3_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-3120-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.65105 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.969047 Arsenic CTD Gene-Chemical Interactions 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.856583 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32774 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02931 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null lymphoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.303198 KELLY CCLE Cell Line Gene CNV Profiles -1.0 -1.73829 REST_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null GTEX-Q2AG-0011-R4A-SM-2HMKA GTEx Tissue Sample Gene Expression Profiles 1.0 0.98003 FOXP2 ENCODE Transcription Factor Targets 1.0 null GUCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4847 HCC70 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.01634 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null HCC1937 CCLE Cell Line Gene CNV Profiles 1.0 1.40333 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF816 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22715 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25969 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65903 H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cortex of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89915 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.921363 GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 0.924192 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924472 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828837 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null SHISA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53993 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM245 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85766 RHBDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50831 GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.824128 dentate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.886485 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.89924 intermediate part of the arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15627 451LU COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH441 DepMap CRISPR Gene Dependency 1.0 3.4267 GTEX-T2IS-2926-SM-32QPO GTEx Tissue Sample Gene Expression Profiles 1.0 1.71834 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r2 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13957 superficial stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13932 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H23 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE174418,GSE174421_2_v_3_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10829 PAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60924 MEST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44312 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE133763_0_v_2_chd1_human RummaGEO Gene Perturbation Signatures -1.0 null Primary somatosensory area, lower limb, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10659 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null orbital frontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.25157 TRIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48413 H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null salivary gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.406694 MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.44684 GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles 1.0 1.77832 dorsolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.986785 striatum_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15356 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.29483 m1 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38426 spleen GTEx Tissue Gene Expression Profiles -1.0 -1.31264 PPARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.8214 NCIH2066 CCLE Cell Line Gene Expression Profiles 1.0 1.98889 GTEX-QDT8-0011-R10A-SM-32PKG GTEx Tissue Sample Gene Expression Profiles 1.0 1.20506 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24979 Simple lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42338 ZNF467 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65467 WT1-25993318-PODOCYTE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null liver GTEx Tissue Gene Expression Profiles -1.0 -1.31937 Perturb_4944_KO_Rybp/Yaf2/Prc1_SRP247114 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 PLTP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94477 GTEX-TSE9-0011-R1A-SM-3DB7E GTEx Tissue Sample Gene Expression Profiles 1.0 0.836641 DYNLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31525 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null HSD3B7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27286 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LFNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19775 anterior pretectal nucleus, dorsal superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0351 GTEX-RNOR-2326-SM-2TF4I GTEx Tissue Sample Gene Expression Profiles 1.0 1.366 ARFIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94123 temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03076 TP53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37498 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.07656 SW948 CCLE Cell Line Gene CNV Profiles 1.0 1.46802 cell-substrate adherens junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.170888 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01934 DMS454 CCLE Cell Line Gene CNV Profiles -1.0 -1.37518 17910759-TableS5 GeneSigDB Published Gene Signatures 1.0 null NCIH2023 CCLE Cell Line Gene CNV Profiles 1.0 1.62374 LU-134-A COSMIC Cell Line Gene Mutation Profiles 1.0 null PALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92898 SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.908324 RCOR1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adenomatous Polyposis Coli DisGeNET Gene-Disease Associations 1.0 null amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17633 MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H661 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NT5C3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95497 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18583 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64437 SLC19A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62875 SHPK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59092 GTEX-WZTO-2826-SM-3NM8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.92963 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CXCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52706 NAXE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85341 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050605 SLC25A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56868 UBA52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03659 TAF1_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FIGNL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36137 Integrin alphav-beta1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.61 JL1 CCLE Cell Line Gene CNV Profiles 1.0 1.49179 REST_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE169356_0_v_3_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null MAN1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7068 PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAFF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60559 GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.77491 pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.901805 FOXP1 ChEA Transcription Factor Targets 1.0 null PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN Rummagene Transcription Factor Associations 2026 1.0 null PLCPRF5 DepMap CRISPR Gene Dependency 1.0 2.89572 496100455_FWM_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.3816 HMGN3 ENCODE Transcription Factor Targets 1.0 null H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERG28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66298 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF493 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25557 lateral terminal nucleus of the accessory optic tract, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19782 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06519 GTEX-NPJ7-0011-R10A-SM-2I3E5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28942 KCNIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00526 MPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72316 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.88878 H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3425 ADGRA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98945 LCLC103H CCLE Cell Line Gene Expression Profiles -1.0 -1.88798 GSE226439,GSE226441_6_v_2_hnf4g_human RummaGEO Gene Perturbation Signatures -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3939 GTEX-WVLH-0011-R11A-SM-3MJFO GTEx Tissue Sample Gene Expression Profiles 1.0 1.79867 SLC39A13_Deficiency_GDS3485_570_mouse_Chondrocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.42033 Lobule III Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0872 GPR173 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59446 VZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.980571 YY1 ENCODE Transcription Factor Targets 1.0 null polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30603 FH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20531 GTEX-XOTO-0011-R8A-SM-4B65J GTEx Tissue Sample Gene Expression Profiles 1.0 0.902179 PE/CA-PJ15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828837 LRCH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55599 GSE171401_1_v_0_adnp_mouse RummaGEO Gene Perturbation Signatures -1.0 null pancreas HPA Tissue Gene Expression Profiles 1.0 0.948627 globus pallidus, internal segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29944 Perturb_79_KD_BAP18_SRP074464 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.89356 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29233 GSE93674_1_v_0_ezh2_mouse RummaGEO Gene Perturbation Signatures -1.0 null fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08351 COLO-679 COSMIC Cell Line Gene Mutation Profiles 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null THTPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6788 subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.45655 primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05154 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE180525,GSE180528_2_v_0_tbx3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE180185_4_v_10_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE232624_4_v_3_ethanol_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-X585-0011-R10A-SM-46MUY GTEx Tissue Sample Gene Expression Profiles 1.0 1.18487 Anxiety Disorders CTD Gene-Disease Associations 1.0 1.18193 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53414 NR1I3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75007 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50846 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Ventral posterolateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.0632 NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null Lobule III, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0281 REST ENCODE Transcription Factor Targets 1.0 null superficial stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56293 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053992 Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2366 REST_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10971 OVMANA DepMap CRISPR Gene Dependency 1.0 3.88873 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Gene_name_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null EBC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-500a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 phosphatidylinositol-4,5-bisphosphate binding GO Molecular Function Annotations 2023 1.0 null WAC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10158 CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC4777381-pone.0150624.s007.xlsx-dif_exp_AD-ZBTB38_ZBTB38 Rummagene Transcription Factor Associations 2026 1.0 null TYK2_KD_GDS4754_158_human_JURKAT GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-514 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 ZNF331 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.5291 SBC5 CCLE Cell Line Gene Expression Profiles -1.0 -1.48485 lymph node HPA Tissue Protein Expression Profiles 1.0 1.97335 mesoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065686 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ESR1 JASPAR Predicted Transcription Factor Targets 1.0 null REST_Panc1_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null SETD1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10483 PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.58356 VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.80499 GTEX-T6MN-2526-SM-32PMN GTEx Tissue Sample Gene Expression Profiles 1.0 1.69593 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.01151 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21306 DCAF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72686 Nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16177 intermediate stratum of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69946 ZNF582 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16346 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZSWIM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32433 Lobule II Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25541 GSE239688_2_v_5_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE157555,GSE157556_4_v_7_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.51947 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.95033 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.990985 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11107 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54547 FUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90987 superior olivary complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.916316 SNU1327 DepMap CRISPR Gene Dependency 1.0 2.82225 SLC18B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78651 Osteopathia striata with cranial sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.943 EZH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82215 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07969 CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.990985 HNRNPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88249 TE4 CCLE Cell Line Gene CNV Profiles 1.0 1.9163 TCF12 ENCODE Transcription Factor Targets 1.0 null Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46552 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23987 MAZ ENCODE Transcription Factor Targets 1.0 null PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles 1.0 0.946365 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26572 MXI1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF837 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56669 GSE232564,GSE232566_0_v_2_nsd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.63032 RHOXF2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10149 PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D4_vs_D9-Unnamed_4_CENPX Rummagene Transcription Factor Associations 2026 1.0 null TAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5902 PLOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68781 PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null PLOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53387 H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE174701_1_v_7_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null bronchoalveolar system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.112037 H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XLM4-0011-R6A-SM-4AT4B GTEx Tissue Sample Gene Expression Profiles 1.0 1.06793 KPNRTBM1 CCLE Cell Line Gene Expression Profiles 1.0 1.50757 germ layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058351 FAM120A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0513 GSE81796_0_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF431 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41224 SNU869 DepMap CRISPR Gene Dependency 1.0 8.20603 FHL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26441 H3K27me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-N7MS-0011-R3a-SM-33HC6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2041 pituitary GTEx Tissue Gene Expression Profiles 1.0 1.3851 intermediate stratum of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02298 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.892676 GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.983451 Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.32962 GTEX-OXRN-2426-SM-2I5EQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.18714 GTEX-XOTO-0011-R7B-SM-4B64R GTEx Tissue Sample Gene Expression Profiles 1.0 0.847592 GSE101239_3_v_2_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05785 ZFTRAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89925 ZNF423 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02657 AP5B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32535 ZMIZ1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96502 M14 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.5337 primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12726 KCNG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58748 PHAX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26234 Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AJUBA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21144 FLNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40881 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26444 MIS18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22488 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.958655 Field CA3, stratum pyramidale Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10225 GTEX-WL46-0011-R5A-SM-3LK6V GTEx Tissue Sample Gene Expression Profiles 1.0 0.835791 BCORL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65478 RNF146 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71855 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.824765 GLRX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87308 EXD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08678 TUHR10TKB CCLE Cell Line Gene Expression Profiles -1.0 -1.93907 orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0405 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.12012 CCSW1 DepMap CRISPR Gene Dependency 1.0 2.49309 POU5F1 ChEA Transcription Factor Targets 1.0 null GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 0.944813 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.871117 VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1617 YEATS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36007 RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.5526 ZBTB7A ENCODE Transcription Factor Targets 1.0 null GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles 1.0 1.59639 Uncharacterised protein family FAM123 InterPro Predicted Protein Domain Annotations 1.0 null NCI-H82 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null NCIH660 CCLE Cell Line Gene Expression Profiles 1.0 1.46747 GSE232624_4_v_5_ethanol_human RummaGEO Drug Perturbation Signatures -1.0 null SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.937236 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02258 Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HACL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30561 H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RORC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9935 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.36469 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11996 CAAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32176 Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.30632 striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.879682 GDPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.66328 HELZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55233 TBP ENCODE Transcription Factor Targets 1.0 null GTEX-WL46-0011-R1A-SM-3LK6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.9605 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM12875_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81481 FUT10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74353 NRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03155 PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null r3 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88221 RNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68672 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16697 CLASP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62068 CAPZB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50344 intermediate stratum of r1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36117 Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3405 hsa-miR-3918 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 HELB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56073 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE210885_0_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34008 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.70418 MXI1 ENCODE Transcription Factor Targets 1.0 null hsa-let-7e TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 SNU5 DepMap CRISPR Gene Dependency 1.0 3.74961 BL5772 (YAP1) NURSA Protein Complexes 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 2.15649 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.836376 liminal part of r2 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31328 PMC9630632-Table1.XLSX-diff_exp_genes-Group_2_vs_3_AND_Group_1_vs_3_NOT_Group_1_vs_2_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.963702 PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Unnamed_2_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null MKN74 CCLE Cell Line Gene CNV Profiles 1.0 1.43361 GTEX-T5JC-0011-R10A-SM-32PM2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08267 biological regulation GO Biological Process Annotations 2015 1.0 null VZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06867 Mouselcells TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.619 ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2145 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924472 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XOTO-0011-R1B-SM-4B65C GTEx Tissue Sample Gene Expression Profiles 1.0 0.851472 GFOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34079 TAS2R5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88722 E2F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9941 GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 0.940373 LB771HNC DepMap CRISPR Gene Dependency 1.0 9.30208 r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37186 amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.87666 HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.990985 hsa-miR-4774-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 SKMEL2 CCLE Cell Line Gene CNV Profiles -1.0 -1.94113 GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.67686 UGT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07234 VMRC-LCD COSMIC Cell Line Gene Mutation Profiles 1.0 null NUCKS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.316 ventral part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22354 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null IFI16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87871 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.14354 Hypertrophy CTD Gene-Disease Associations 1.0 1.10246 GTEX-PVOW-0011-R3A-SM-32PKX GTEx Tissue Sample Gene Expression Profiles 1.0 1.06918 ventral pallidum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04523 NCIH1648 CCLE Cell Line Gene Expression Profiles -1.0 -1.81772 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040151 membrane GO Cellular Component Annotations 2015 1.0 null substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27761 APC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26958 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.979253 PRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45699 superficial stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06105 GTEX-Q2AG-0011-R8A-SM-2HMK5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.893679 REST_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-0011-R3B-SM-3NMC6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13307 Esophageal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.736 hsa-miR-498 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GDM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null VZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35214 CHD1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Nervous system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 Mandibulofacial dysostosis, Guion-Almeida type DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.09 H3K27me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.905669 RCOR3 ChEA Transcription Factor Targets 1.0 null FKBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55283 GTEX-R55E-2526-SM-2TC6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.8858 ventral linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14886 activates GeneRIF Biological Term Annotations 1.0 null SUMO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89857 DNAJC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20519 ChIP_POU5F1_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null L540 CCLE Cell Line Gene CNV Profiles 1.0 1.33642 pancreas GTEx Tissue Gene Expression Profiles 1.0 0.916711 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07928 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.76692 amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.62604 RFLNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8933 GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44675 ChIP_REST_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null REH COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE190316,GSE190324_1_v_9_rbm4_human RummaGEO Gene Perturbation Signatures -1.0 null GADD45G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57051 Metencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844539 GTEX-Q2AG-2926-SM-2HMJ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28204 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.13484 GTEX-S7SE-0011-R6A-SM-2XCD9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.915296 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.69012 ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.9625 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GABPA_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58739 UBTF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.903822 CTBP2 ENCODE Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-DX-A1KW-01A-22R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.63271 MHHES1 CCLE Cell Line Gene CNV Profiles 1.0 1.32826 H1-5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68552 C1GALT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36855 RANGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.36075 LYRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59958 HEC1A CCLE Cell Line Gene CNV Profiles 1.0 1.33298 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K27me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null colorectal GeneRIF Biological Term Annotations 1.0 null Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01409 H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null contrast GeneRIF Biological Term Annotations 1.0 null U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8694 sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.093208 Central nervous system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 PPIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05138 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07668 GTEX-RVPV-0011-R11A-SM-2TF6F GTEx Tissue Sample Gene Expression Profiles 1.0 1.9139 IBA57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38436 Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.372 GTEX-NPJ7-0011-R1a-SM-3GACT GTEx Tissue Sample Gene Expression Profiles 1.0 0.849862 H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE188721_2_v_4_mesp1_human RummaGEO Gene Perturbation Signatures -1.0 null MCAD_KO_GDS4546_423_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NHLRC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50583 internal granular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21282 GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09973 GSE190316,GSE190324_10_v_9_rbm4_human RummaGEO Gene Perturbation Signatures -1.0 null DENND4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95117 GSE126127_5_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNU119 CCLE Cell Line Gene CNV Profiles 1.0 1.81552 GTEX-WHSE-3026-SM-3P5ZH GTEx Tissue Sample Gene Expression Profiles 1.0 1.16845 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.3298 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.2306 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE188721_3_v_1_mesp1_human RummaGEO Gene Perturbation Signatures -1.0 null METTL27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07377 mesenchyme TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.239913 Central lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14966 hsa-miR-4660 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 IZUMO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20174 GRIPAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53713 Perturb_4318_KD_Fos_SRP075838 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -16.5027 RLIM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98686 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55819 COLO-680N COSMIC Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NAT14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91323 ZBTB41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15703 layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20469 pararubral nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02596 647V CCLE Cell Line Gene CNV Profiles -1.0 -3.20165 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01409 GSE205163,GSE205164_1_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null NOS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WVLH-0011-R6A-SM-3MJFZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.851692 REST_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4296 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 ZNF586 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13583 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5228 NCI-H1568 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCKIPSD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64626 m2 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08988 Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null EGR1 ENCODE Transcription Factor Targets 1.0 null UQCRFS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92574 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-2115 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 TFAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32401 Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33041 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 1.09022 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19849 GTEX-N7MT-0011-R7a-SM-2I3FZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.02427 NCIH2227 CCLE Cell Line Gene CNV Profiles 1.0 1.88908 BEN COSMIC Cell Line Gene Mutation Profiles 1.0 null IFI6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23465 LP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.47596 H3K27me3_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-0011-R4B-SM-4AT5C GTEx Tissue Sample Gene Expression Profiles 1.0 0.963464 Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.20782 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H727 COSMIC Cell Line Gene Mutation Profiles 1.0 null B4GALT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12086 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.88811 r6 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24694 HMCB CCLE Cell Line Gene Expression Profiles -1.0 -1.78283 Tadpole TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.828 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059287 WARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7417 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65079 LEPROTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04286 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE205163,GSE205164_5_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF215 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18187 TIGD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01599 HCFC1 ENCODE Transcription Factor Targets 1.0 null YIF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98854 signal transduction GO Biological Process Annotations 2015 1.0 null VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0199 GTEX-QVJO-0011-R6A-SM-2S1QN GTEx Tissue Sample Gene Expression Profiles 1.0 1.065 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13507 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NYAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.54851 Field CA3, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13337 GTEX-X261-3226-SM-3NMC3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.97198 STUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44342 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18038 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAB33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11228 ECC12 CCLE Cell Line Gene Expression Profiles 1.0 1.54941 TIMM29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48042 GTEX-P44H-0011-R4A-SM-2XCEW GTEx Tissue Sample Gene Expression Profiles 1.0 0.832198 MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830333 GSE93674_2_v_3_ezh2_mouse RummaGEO Gene Perturbation Signatures 1.0 null MAPKAPK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26128 MAP2K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16679 superficial stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00126 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEUROD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32131 H3K27me3_Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Habenula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.862 MYF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94761 CRTAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10523 SK-MEL-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null FNDC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22615 GTEX-X4XX-0011-R6B-SM-46MWP GTEx Tissue Sample Gene Expression Profiles 1.0 0.931065 GSE205976,GSE205978_1_v_4_cep83_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA3, stratum lucidum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17368 GTEX-NL3H-0011-R3a-SM-2I3GL GTEx Tissue Sample Gene Expression Profiles 1.0 1.04677 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MT-CYB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9444 retroreuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19854 inner SZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.912671 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null REST_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61736 HSPG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3176 COLO-205 COSMIC Cell Line Gene Mutation Profiles 1.0 null SMIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05241 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.37414 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.898546 REST_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6725 GTEX-T6MN-0011-R7A-SM-32QP5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.908565 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-516b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.98868 Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2351 DSP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6551 beta-catenin-TCF complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.867 CTCF_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.7157 COLO704 CCLE Cell Line Gene Expression Profiles 1.0 1.46733 KDM5B ENCODE Transcription Factor Targets 1.0 null PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null intermedioposterior nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12679 REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P44H-0011-R5A-SM-2XCEX GTEx Tissue Sample Gene Expression Profiles 1.0 0.98278 MT-ND2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20324 MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844539 dorsal part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32267 bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.283899 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BACH1 ENCODE Transcription Factor Targets 1.0 null Bladder GTEx Tissue Gene Expression Profiles 2023 1.0 4.01321 OCI-LY-19 COSMIC Cell Line Gene Mutation Profiles 1.0 null PANC1005 DepMap CRISPR Gene Dependency 1.0 2.16931 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX Rummagene Transcription Factor Associations 2026 1.0 null ABHD17C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37783 HIRIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19264 GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles 1.0 1.08769 Copula pyramidis, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03959 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27919 RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8109 H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-4320 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10289 SUPT7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65541 KMS26 CCLE Cell Line Gene CNV Profiles -1.0 -1.56417 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55E-0011-R1A-SM-2TC6N GTEx Tissue Sample Gene Expression Profiles 1.0 0.91406 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04055 CCDC153 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52988 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.974986 MDA-MB-436 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAX_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR Rummagene Transcription Factor Associations 2026 1.0 null EAF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14492 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07378 gracile nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.924736 REST_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61513 outer CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.866735 Paraspeckles COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.88 PPP2R5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08814 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.963702 MAVER1 DepMap CRISPR Gene Dependency 1.0 2.20897 QPRT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24094 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.903351 primary motor cortex (area M1, area 4)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.931023 brain stem TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null KURAMOCHI CCLE Cell Line Gene Expression Profiles -1.0 -1.52179 trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.041519 GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles 1.0 1.5708 DIABLO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2478 GSE142684_0_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF496 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77624 DYNLT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45842 Lobule II, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39904 ACKR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31968 internal granular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9066 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POFUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62525 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Secretory progenitor cell_Small intestine_Human CellMarker Gene-Cell Type Associations 1.0 null RAB11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40808 cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.57735 GTEX-WVLH-3026-SM-3MJG9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37811 GSE152050,GSE152052_1_v_0_arid1a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28371 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19584 COLO-829 COSMIC Cell Line Gene Mutation Profiles 1.0 null RBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99555 molecular layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50977 H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.17277 GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 0.901419 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF443 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67201 Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27235 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.937085 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.4348 Anteroventral nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55259 GTEX-WVLH-0011-R10A-SM-3MJFM GTEx Tissue Sample Gene Expression Profiles 1.0 1.24514 CTCF_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null r7 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68138 mouth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055711 hsa-miR-3122 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 GSE181959_3_v_2_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38818 H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null medial geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19218 GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles 1.0 0.843669 Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FIZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87066 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NUP43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5868 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-331-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null NR1I2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0176 ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3066 USP28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07256 mantle zone of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81406 RH30 DepMap CRISPR Gene Dependency 1.0 3.67043 mantle zone of m2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17286 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.65833 Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89671 attention deficit hyperactivity disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.04167 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSKIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36269 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2418 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38512 r3 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62515 SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreas-pancreatic alpha cell Tabula Sapiens Gene-Cell Associations 1.0 0.397628 TGFBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75271 GTEX-WL46-2926-SM-3LK82 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23013 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null 22RV1 CCLE Cell Line Gene CNV Profiles -1.0 -2.11296 SARM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88645 KRT19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41478 8505C COSMIC Cell Line Gene Mutation Profiles 1.0 null REST_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.882809 Primary motor area, Layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07165 substantia innominata/basal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.27403 TCAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45263 SK-UT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GPATCH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23139 nasal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.566828 hsa-miR-3135b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GTEX-XLM4-0011-R3B-SM-4AT6E GTEx Tissue Sample Gene Expression Profiles 1.0 1.1001 IFNAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30471 hsa-miR-766 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.432 REST_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5311 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3378 TMEM47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14844 GPBP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74624 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null KDM5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33294 Microtubule plus-end COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.946 superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.18746 burkitt lymphoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.620621 lipid binding GO Molecular Function Annotations 2015 1.0 null VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42694 KBTBD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23411 PGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13476 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.84642 GSE133087_1_v_2_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null Dentate gyrus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62767 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 2.1236 cell part GO Cellular Component Annotations 2015 1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.852408 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02258 PRR14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67217 subcuneiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78723 MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-let-7c TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 GSE111660_1_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null JHOM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.37558 lateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08038 GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles 1.0 1.69306 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE124048,GSE124067_1_v_0_irf6_mouse RummaGEO Gene Perturbation Signatures -1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051426 GTEX-WVLH-2926-SM-3MJG5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.80957 Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H660 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE144231_4_v_1_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null SCCPDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62509 GTEX-WL46-0011-R10A-SM-3MJFQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.24644 MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924472 RAB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90802 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33379 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE180525,GSE180528_1_v_0_tbx3_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_16087_KD_Pml_SRP306364 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.3286 PLPBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89867 STARD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59099 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.075107 GSE169356_0_v_4_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.63435 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10566 PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11243 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1066 hsa-miR-3689a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.16981 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.47526 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06904 hsa-miR-549 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of Wnt signaling pathway GO Biological Process Annotations 2025 1.0 null RAI14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88474 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar white matter Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67697 Perineuronal net COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.002 GSE129241_4_v_6_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null BAX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16783 IGFBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82788 NCI-H835 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE157555,GSE157556_3_v_7_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PRRX2_PRRX2 Rummagene Transcription Factor Associations 2026 1.0 null GSE115542_2_v_4_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null iPS-18 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.81836 SCAF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29522 TMEM140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27842 RELL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32824 WM2664 CCLE Cell Line Gene Expression Profiles -1.0 -1.4802 hsa-let-7a TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.902986 EMTOKA DepMap CRISPR Gene Dependency 1.0 3.26305 FAAP20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4165 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0565 Fatty acid elongase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.563 PLBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6722 HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.85324 GTEX-NPJ7-0011-R4a-SM-2I3GJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.859302 Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF322 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42377 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.45083 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 1.02137 GTEX-NPJ8-1526-SM-2D7VU GTEx Tissue Sample Gene Expression Profiles 1.0 1.14321 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8 Rummagene Transcription Factor Associations 2026 1.0 null raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03086 8MGBA CCLE Cell Line Gene Expression Profiles -1.0 -1.91908 GTEX-WZTO-0011-R10B-SM-4E3KB GTEx Tissue Sample Gene Expression Profiles 1.0 1.18531 GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03535 Meiotic cohesin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.672 ZNF24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19706 CEP20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04624 FGF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09394 CHP126 CCLE Cell Line Gene Expression Profiles 1.0 2.27161 ZNF250 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.75837 TEAD4_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64214 GTEX-QVJO-1426-SM-2S1QY GTEx Tissue Sample Gene Expression Profiles 1.0 1.27069 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054879 protein binding GO Molecular Function Annotations 2015 1.0 null EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null granule cell layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71085 GTEX-T5JC-0011-R5A-SM-32PLK GTEx Tissue Sample Gene Expression Profiles 1.0 0.866548 NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null C1orf115 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76829 MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCEA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4031 primary motor cortex (area M1, area 4)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09248 Perturb_69_KD_SMARCB1_SRP280151 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37542 TT CCLE Cell Line Gene CNV Profiles 1.0 2.68516 NID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80597 Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00332 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.89924 H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBX21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55736 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11065 POLRMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84835 Brain Lower Grade Glioma_LGG_TCGA-HT-A5R9-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06907 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20682 cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.933286 GTEX-T2IS-3026-SM-32QPM GTEx Tissue Sample Gene Expression Profiles 1.0 1.26018 UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904657 GSE169356_0_v_1_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR Rummagene Transcription Factor Associations 2026 1.0 null cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SW900 CCLE Cell Line Gene CNV Profiles 1.0 1.44041 APPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87836 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4XX-3026-SM-3NMB2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27769 GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 1.88875 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC Rummagene Transcription Factor Associations 2026 1.0 null Perturb_4868_KO_NEUROG3_ERP110708 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.67822 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8368 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RARB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.073 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.93131 hsa-miR-4474-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 MRPL43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06962 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01934 GTEX-NPJ8-0011-R10A-SM-2YUMO GTEx Tissue Sample Gene Expression Profiles 1.0 1.2492 dorsolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09461 hsa-miR-215 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25854 ZNF800 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92847 r2 part of superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0224 CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NACA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78296 GSE214382,GSE214383_4_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1815 Medial geniculate complex, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11599 r3 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14024 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.0276 Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27329 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.69312 cellular_component GO Cellular Component Annotations 2015 1.0 null central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36831 NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.16807 NKX2-8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79801 KLF4-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.850051 cell-substrate junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.164315 intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.59874 C5orf34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39426 JUND_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM234B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13901 primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.93131 ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19256 MAP3K14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45406 Culmen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07092 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.845708 GTEX-OXRN-0011-R10A-SM-2I5GC GTEx Tissue Sample Gene Expression Profiles 1.0 1.08429 EGFL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09144 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01409 Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X585-0011-R3B-SM-46MVG GTEx Tissue Sample Gene Expression Profiles 1.0 1.19494 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NPM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48386 GTEX-WL46-0011-R3A-SM-3TW8E GTEx Tissue Sample Gene Expression Profiles 1.0 1.24897 GSE195743_1_v_4_lhx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null EFNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24505 hsa-miR-4299 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GARIN5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33132 FBXW8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69278 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null MTFMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06997 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NAGPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1724 white matter of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10354 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.17813 MKN7 CCLE Cell Line Gene CNV Profiles -1.0 -1.38847 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.943192 GTEX-N7MS-0011-R2a-SM-2HML6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.926644 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58013 GSE111660_2_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null C10orf82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82599 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.937493 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IMR32 CCLE Cell Line Gene Expression Profiles 1.0 2.29034 hsa-let-7i TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 TMEM8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.42162 PHYKPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79277 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29813 Principal sensory nucleus of the trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43928 REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.815104 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE188721_3_v_4_mesp1_human RummaGEO Gene Perturbation Signatures -1.0 null RERFLCSQ1 DepMap CRISPR Gene Dependency 1.0 3.7718 SLC25A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03983 FBXO28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2558 adherens junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.119 primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05923 GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06705 PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.71835 Lateral habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38208 Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11304 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54424 AEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49807 GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 1.14224 POLR2E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32761 exocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.271604 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2144 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CNOT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82637 CERS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2097 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.166319 QGP1 CCLE Cell Line Gene Expression Profiles 1.0 1.77647 BABAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23655 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE115542_5_v_1_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null PMC10248509-Data_Sheet_6.CSV--GSE66724_DE-Genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.916799 GTEX-XOTO-0011-R11B-SM-4B64O GTEx Tissue Sample Gene Expression Profiles 1.0 1.68585 Dentate gyrus, granule cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73211 AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 2q21 1 copy number variation syndrome WikiPathways Pathways 2024 1.0 null H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05471 MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.957341 SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5406 DUSP22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79056 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76732 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-514b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 INO80D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8635 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null phosphatidylinositol-4,5-bisphosphate binding GO Molecular Function Annotations 2025 1.0 null MERO83 DepMap CRISPR Gene Dependency 1.0 2.0071 PTOV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82067 REST_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PNPLA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38109 496100507_FWM_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.10939 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.49572 Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33108 LU-135 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null JMSU1 CCLE Cell Line Gene CNV Profiles 1.0 1.57806 GSE163240_3_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.37156 inner CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.876493 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.87473 CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0342 FOXN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16462 GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 1.59449 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neurodegeneration with brain iron accumulation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.081 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050599 hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25265 REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Orbital area, lateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80066 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 1.25142 GSE212312_1_v_3_fbxw7_human RummaGEO Gene Perturbation Signatures 1.0 null POU5F1-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054881 pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.729357 GTEX-R55E-0011-R4A-SM-2TC5H GTEx Tissue Sample Gene Expression Profiles 1.0 0.945952 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21603 Preribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.998 MAP2K1_knockdown_134_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.59296 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29038 ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.980065 GSE174701_1_v_0_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SUZ12 ENCODE Transcription Factor Targets 1.0 null mantle zone of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31561 GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.924203 SETDB1-19884257-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null ACTMAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15255 inner ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.487886 GNB5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11103 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24993 ERCC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02729 Epithalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26239 Entorhinal area, medial part, dorsal zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41757 GTEX-T2IS-0011-R5A-SM-32QP4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.847454 ZNF503 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98105 NISCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53228 hsa-miR-4288 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 POU3F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02798 SIK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67083 GSE88819_3_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7454 hsa-miR-4775 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GDF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33704 NABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51428 UFC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32422 Esophageal atresia/tracheoesophageal fistula DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.229 NR2C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7399 CDK5R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48425 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040255 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.17071 superficial stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14732 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PAX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9836 PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Ensembl_ID_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD4 ChEA Transcription Factor Targets 1.0 null prepontine hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20797 F36P CCLE Cell Line Gene CNV Profiles -1.0 -1.95605 REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85476 GSE239688_4_v_0_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36855 LUC7L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39472 GTEX-WWYW-0011-R10A-SM-3NB35 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08827 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null AREB6 MotifMap Predicted Transcription Factor Targets 1.0 null GSE153836_14_v_5_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null ACTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59989 superficial stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03483 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55508 SUPT3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92286 hsa-miR-4265 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 DGAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49233 subbrachial nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92938 GTEX-WL46-0011-R2A-SM-3LK6O GTEx Tissue Sample Gene Expression Profiles 1.0 0.892236 HOXA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21519 SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-0011-R5B-SM-3NMC5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.904047 Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99891 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054057 inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.924907 GABPA ENCODE Transcription Factor Targets 1.0 null TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0344 UBTF ENCODE Transcription Factor Targets 1.0 null CTCF_DEPLETION_GDS3294_97_mouse_germinal vesicle (GV) oocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924472 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10971 Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.5832 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16697 ATOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48649 intermediate stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2968 hsa-miR-5047 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GABPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17793 EMC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63943 GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.70076 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50576 CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null suggesting GeneRIF Biological Term Annotations 1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.84737 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.97337 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054415 red nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08972 STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLA2G12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.20742 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.975872 NTMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97162 GTEX-PWO3-0011-R3A-SM-2I5EX GTEx Tissue Sample Gene Expression Profiles 1.0 0.851577 periventricular stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10448 REST_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IP6K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61641 intermediate stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10398 CAL27 DepMap CRISPR Gene Dependency 1.0 2.80821 GLRX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98101 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_SETDB1_19884257 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null HT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77101 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.89995 GTEX-XLM4-3026-SM-4AT6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.20704 hsa-miR-501-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20036 cerebellum TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8012-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15494 NCIH1105 CCLE Cell Line Gene Expression Profiles 1.0 1.67536 TEAD4 ENCODE Transcription Factor Targets 1.0 null Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.21762 PMC4777381-pone.0150624.s006.xlsx-dif_exp_AD-ZBTB38_ZBTB38 Rummagene Transcription Factor Associations 2026 1.0 null PIGV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51906 ventrolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.13018 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57695 DUS4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59294 periventricular stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1079 etoposide_mus musculus_gpl6887_gse33626 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Reflex, Abnormal CTD Gene-Disease Associations 1.0 1.30421 SHQ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62367 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.297 CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19849 ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WWYW-0011-R1A-SM-3TW8G GTEx Tissue Sample Gene Expression Profiles 1.0 0.967604 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_KLF4_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.868513 ChIP_TCFCP2L1_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null isthmic alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0256 REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13951_KD_ASCL1_SRP201348 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 intermediate stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04462 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXC2_FOXC2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 1.15474 GTEX-X4XX-0011-R3B-SM-46MWK GTEx Tissue Sample Gene Expression Profiles 1.0 1.10459 REST_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles 1.0 0.888721 NCIH526 CCLE Cell Line Gene Expression Profiles 1.0 1.40973 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.867658 GTEX-WHSE-0011-R3A-SM-3P5ZM GTEx Tissue Sample Gene Expression Profiles 1.0 0.854791 PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4 Rummagene Transcription Factor Associations 2026 1.0 null TRIM32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13128 SP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.880247 HT CCLE Cell Line Gene CNV Profiles -1.0 -2.30558 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null HARBI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55987 MOLT-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.843171 cetuximab_homo sapiens_gpl570_gse21483 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ventral subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30028 RAB3IL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08385 H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null COR-L303 COSMIC Cell Line Gene Mutation Profiles 1.0 null SLC37A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34555 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05022 mantle zone of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22427 GTEX-QVJO-0011-R5A-SM-2S1QM GTEx Tissue Sample Gene Expression Profiles 1.0 1.03748 LRRC41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47236 ZC3H7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72091 hsa-miR-632 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09987 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RTCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01286 OVMANA CCLE Cell Line Gene CNV Profiles 1.0 1.78995 TBX2-33478486-IMR90-HUMAN-LUNG ChEA Transcription Factor Targets 2022 1.0 null KXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37482 GTEX-N7MS-0011-R5a-SM-2HMK8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.906437 MYO1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57953 GSE210682_0_v_3_methadone_human RummaGEO Drug Perturbation Signatures 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02053 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7941 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13631 primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.86064 TMED3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27661 REST_PFSK-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.66972 lymphoid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071674 GSE225901_2_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null SRSF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06456 layer 1 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15267 layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46301 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PKNOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56328 EZH2 ENCODE Transcription Factor Targets 1.0 null CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7SE-0011-R7A-SM-2XCDI GTEx Tissue Sample Gene Expression Profiles 1.0 0.978953 Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-0011-R11A-SM-2HMJS GTEx Tissue Sample Gene Expression Profiles 1.0 2.09611 regulation of canonical Wnt signaling pathway GO Biological Process Annotations 2023 1.0 null ZNF781 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87941 olivary pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13038 intermediate stratum of m2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09764 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.49133 GSE239688_4_v_1_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null RRP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21255 mantle zone of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39011 KMT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38019 GSE195559_6_v_1_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56113 Hindbrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 RBM15B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19351 GSE238005_0_v_3_c9orf72_human RummaGEO Gene Perturbation Signatures -1.0 null CCNG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84334 Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.786 BICR56 DepMap CRISPR Gene Dependency 1.0 2.80359 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.269 GTEX-X585-0011-R1B-SM-46MVE GTEx Tissue Sample Gene Expression Profiles 1.0 0.909369 PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.01839 GTEX-QVUS-2826-SM-3GADB GTEx Tissue Sample Gene Expression Profiles 1.0 1.02828 CHST13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6506 Perturb_78_KD_BAP18_SRP074464 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.52375 FXYD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27057 DMRTA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34985 hindbrain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TMC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2984 GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.80264 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844539 PLEKHG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45158 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17757 RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4291 hsa-let-7f TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 r1 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7216 GSE149035_3_v_5_hepacam_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.21249 ZBTB7A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-0011-R9A-SM-2S1QH GTEx Tissue Sample Gene Expression Profiles 1.0 0.894748 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_HAND1 Rummagene Transcription Factor Associations 2026 1.0 null HOXB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5376 interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.888831 Tail fin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.893 ZNF232 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16691 CAL148 CCLE Cell Line Gene CNV Profiles -1.0 -2.1513 BPNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27341 CD320 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99887 VOPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23298 hsa-miR-4795-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 hsa-miR-764 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GSE153836_14_v_1_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null MFAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9641 VMRCLCD CCLE Cell Line Gene Expression Profiles 1.0 1.7895 subpretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47696 ZNF75A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.1027 KIFC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91484 Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE214382,GSE214383_1_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null Fasting insulin GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.7 PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Supplemental_Table_8_NEUROG3_bound_genes_and_expression_in_islet_lineage_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles 1.0 1.28915 METRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8713 globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.901171 Field CA3, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1686 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903697 ZNF426 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45931 HDAC2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4723 JTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84568 GORASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58064 ARID4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75743 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA3, stratum lacunosum-moleculare Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20867 REST_PFSK-1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-0011-R6A-SM-2TF71 GTEx Tissue Sample Gene Expression Profiles 1.0 0.857773 WM88 DepMap CRISPR Gene Dependency 1.0 2.28492 DTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67075 FOXN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88783 VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30559 regulation of cellular process GO Biological Process Annotations 2015 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3985 VZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.880688 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02123 PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Field CA3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06459 GTEX-RVPV-0011-R3A-SM-2TF63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02293 PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null TRIM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45218 LIPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0767 STAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16191 SMC3 ENCODE Transcription Factor Targets 1.0 null hsa-miR-4722-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Lobules IV-V, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0076 Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55406 GSE226408_1_v_0_inpp4b_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70699 YPEL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89388 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles 1.0 2.16888 medial pallium (hippocampal allocortex) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00891 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.43973 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SRRD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22713 ARFGAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46613 caudal interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10594 GSE90019,GSE90020_5_v_2_phf8_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09818 Gli2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.1705 BTRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44794 PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.849406 ASCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05557 D-502MG COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16697 PRMT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62194 CBX3 ENCODE Transcription Factor Targets 1.0 null ZNF540 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12236 RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Colon adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.841227 GTEX-N7MS-2526-SM-2D7W3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.21498 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03607 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040497 GTEX-WZTO-0011-R4A-SM-3NMC7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07656 WDR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11012 WNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53765 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ABL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20406 CTDSPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93333 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX Rummagene Transcription Factor Associations 2026 1.0 null GSE88819_3_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SIN3A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3689c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903697 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27101 ONS-76 COSMIC Cell Line Gene Mutation Profiles 1.0 null parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25992 CNOT10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.585 medial basal reticular formation of m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03381 FURIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76925 GTEX-QVUS-0011-R3A-SM-3GAFD GTEx Tissue Sample Gene Expression Profiles 1.0 1.05865 Ventral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40004 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2793 actomyosin COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.252202 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 1.04621 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065477 temporal muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50868 SP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.836522 NCIH1793 CCLE Cell Line Gene CNV Profiles -1.0 -1.55333 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE154197_1_v_2_ints13_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064301 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02245 GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.31127 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27508 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01409 mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -3.09767 JHOC5 DepMap CRISPR Gene Dependency 1.0 2.18041 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BICR18 CCLE Cell Line Gene CNV Profiles 1.0 2.48467 Motor nucleus of trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90269 cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14121 Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056541 CHGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1894 PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null NCIH716 CCLE Cell Line Gene Expression Profiles 1.0 1.57688 hsa-miR-4662a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 LDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27646 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.990985 PCDHAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06615 GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.85531 Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.41203 TMEM128 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79454 H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6801 hsa-miR-192 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 RHOD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78096 BCP1 CCLE Cell Line Gene Expression Profiles 1.0 3.32748 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05732 H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE115542_5_v_3_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null cortex of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13965 GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 1.91875 GSE190316,GSE190324_6_v_9_rbm4_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.2584 GTEX-TSE9-0011-R8A-SM-3DB7R GTEx Tissue Sample Gene Expression Profiles 1.0 0.891286 molecular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08256 PIP4P2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55512 Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01649 r8 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10853 ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.389289 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE180185_4_v_1_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.97915 hsa-miR-541 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.68423 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08078 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3C15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49622 superficial stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.2056 SP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1808 USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9171 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null peripheral nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213112 NCIH1650 DepMap CRISPR Gene Dependency 1.0 2.87687 GTEX-X585-0011-R6A-SM-46MVJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.994827 KIF5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.046 NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.990985 GTEX-N7MS-0011-R10A-SM-2HMJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.26702 KIFBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42997 HT55 COSMIC Cell Line Gene Mutation Profiles 1.0 null USF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74356 OXER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71094 CELF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29496 Perihypoglossal nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18459 DEF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09837 NKAIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47414 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XOTO-0011-R3A-SM-4B64W GTEx Tissue Sample Gene Expression Profiles 1.0 1.15666 KYSE270 DepMap CRISPR Gene Dependency 1.0 2.54471 orbital frontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.870811 HOXA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83823 GTEX-NL4W-0011-R8a-SM-2I3G4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.96669 CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03232 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-0011-R11A-SM-32PMB GTEx Tissue Sample Gene Expression Profiles 1.0 1.48146 MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33213 NCI-H1437 COSMIC Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.84649 PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null NCIH2227 CCLE Cell Line Gene Expression Profiles 1.0 1.42402 Adamantinous craniopharyngioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.379 GTEX-X585-3026-SM-46MWF GTEx Tissue Sample Gene Expression Profiles 1.0 0.983132 GTEX-WZTO-0011-R11A-SM-4E3K9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.93382 ZNF154 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65156 GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 1.11437 GTEX-WHSE-0011-R8A-SM-3P5Z1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.850933 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57226 YY1-33199912-293T-HUMAN-KIDNEYEMBRYO ChEA Transcription Factor Targets 2022 1.0 null NCIH1299 CCLE Cell Line Gene CNV Profiles 1.0 1.57607 TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF555 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56455 H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null INHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63332 nucleus of Darkschewitsch, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.88467 BTG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80699 MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERGIC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77213 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6843 Orbital area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84897 SDHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12569 GSE119498_6_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.84774 GSE144231_2_v_1_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HIPK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31477 HYOU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76707 GTEX-PVOW-2526-SM-2XCF7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23495 GSE212299_2_v_1_abi3_mouse RummaGEO Gene Perturbation Signatures -1.0 null HOUAI DepMap CRISPR Gene Dependency 1.0 6.8415 ENTPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26604 TES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16584 DYRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15694 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TE8 CCLE Cell Line Gene Expression Profiles -1.0 -2.48201 SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null SW962 COSMIC Cell Line Gene Mutation Profiles 1.0 null autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.786394 VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.881843 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87843 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.80613 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null QRICH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27235 GTEX-RU72-0011-R2A-SM-2TF6O GTEx Tissue Sample Gene Expression Profiles 1.0 0.881861 SLFN11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98406 GTEX-WZTO-0011-R6B-SM-4E3J6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00779 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-0011-R7A-SM-32PKF GTEx Tissue Sample Gene Expression Profiles 1.0 1.0369 HINT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80528 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.65927 GTEX-T6MN-0011-R1A-SM-32QOY GTEx Tissue Sample Gene Expression Profiles 1.0 0.882317 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03791 PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1 Rummagene Transcription Factor Associations 2026 1.0 null REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Lung bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.059 MFNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64608 orbital frontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04258 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.02153 GSE126127_0_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AGAP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57787 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null r2 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55545 GTEX-XLM4-2926-SM-4AT59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.99645 Lobules IV-V, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15841 dorsal subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1628 SUZ12_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.949329 CCDC61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90336 GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.0163 REST_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_K27me3_17603471_mouseNPC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE159446,GSE159449_1_v_0_tunicamycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null CNNM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19852 H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01409 ZNF79 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96694 GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1963 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20577 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46597 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33961 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.963702 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.14 FAIM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12272 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BBLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85485 PPP1R3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62631 intermediate stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60924 GPBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7969 KCTD19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10601 Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNASE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33372 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nucleus sagulum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42461 GTEX-WZTO-2926-SM-3NM9I GTEx Tissue Sample Gene Expression Profiles 1.0 1.17286 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.17595 H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVOL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42741 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.82925 GSE95771_0_v_2_ruxolitinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.61578 CCDC177 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11927 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2A MotifMap Predicted Transcription Factor Targets 1.0 null r2 part of vestibular sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01948 HMBOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25883 FTL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53822 G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.92518 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.963702 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1979 inner CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.93472 dorsolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.09288 SMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66886 primary auditory cortex (core)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06857 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REST_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null TMEM219 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64757 PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX2_Deficiency_GDS4853_319_human_AZ-521 gastric cancer (GC) cell line - 8 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCIH727 CCLE Cell Line Gene Expression Profiles 1.0 1.64196 GSE190316,GSE190324_1_v_11_rbm4_human RummaGEO Gene Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2835-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ7-0011-R6a-SM-2I3G7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0728 PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF Rummagene Transcription Factor Associations 2026 1.0 null GSE111660_1_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.67336 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AMER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18516 FAM8A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87953 UBIAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95626 GSE154577_2_v_12_plagl1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S7SE-0011-R1A-SM-2XCDE GTEx Tissue Sample Gene Expression Profiles 1.0 0.828036 H2AFZ ENCODE Transcription Factor Targets 1.0 null HEC1B DepMap CRISPR Gene Dependency 1.0 5.06324 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2082 REST_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAB3GAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88741 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSMD13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59942 TCF12_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF713 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39699 Medial geniculate complex, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19801 hsa-miR-4742-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 STX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52375 CEBPB ENCODE Transcription Factor Targets 1.0 null STAT3_deficiency_GDS3106_58_mouse_type II alveolar cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE142684_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11274 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.14781 GTEX-T6MN-2626-SM-32PMQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.24162 GTF2F1 ENCODE Transcription Factor Targets 1.0 null GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 1.18892 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.06409 CCNT2 ENCODE Transcription Factor Targets 1.0 null cuneiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70263 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.39148 SLC9A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94512 GTEX-XLM4-0011-R10A-SM-4AT5P GTEx Tissue Sample Gene Expression Profiles 1.0 1.11937 GTEX-T2IS-0011-R11A-SM-32QPC GTEx Tissue Sample Gene Expression Profiles 1.0 1.63604 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.871467 GGT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20646 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.873422 SIN3B ChEA Transcription Factor Targets 1.0 null Perturb_8833_KO_RING1A_SRP345831 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GALR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85553 MHH-PREB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.2781 primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.889285 HECTD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84278 Copula pyramidis, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04161 Dentate gyrus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52776 BRCA1 ENCODE Transcription Factor Targets 1.0 null GTEX-X4XX-0011-R8B-SM-46MWM GTEx Tissue Sample Gene Expression Profiles 1.0 1.0748 hsa-miR-4721 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GTEX-NL3H-0011-R10A-SM-2I3E9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33746 lung bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.36906 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNF112 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23301 NCIH209 CCLE Cell Line Gene Expression Profiles 1.0 1.3743 GTEX-TSE9-0011-R6A-SM-3DB7L GTEx Tissue Sample Gene Expression Profiles 1.0 0.907004 Ventral anterior-lateral complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06418 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0084 ZNF835 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37121 EIF3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00877 TMOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11651 NCIH2291 CCLE Cell Line Gene CNV Profiles 1.0 1.45061 ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3748 PEX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04284 GSE218580_1_v_5_fentanyl_mouse RummaGEO Drug Perturbation Signatures 1.0 null LRP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90208 HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBXIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02043 cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.953374 NCIH810 CCLE Cell Line Gene Expression Profiles 1.0 2.65864 496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.06546 ARC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74575 hilus of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72418 GTEX-T6MN-0011-R5A-SM-32QPD GTEx Tissue Sample Gene Expression Profiles 1.0 0.872986 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25883 brain HPA Tissue Gene Expression Profiles 1.0 2.24176 Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null METTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75791 Hippocampal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18979 OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37355 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18294 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2154 GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 2.01748 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02258 GTEX-RU72-0011-R5A-SM-2TF6U GTEx Tissue Sample Gene Expression Profiles 1.0 0.893084 inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20142 LRRC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47499 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0011-R3A-SM-2HMJ9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3265 VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1313 POLR2A ENCODE Transcription Factor Targets 1.0 null PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WWYW-0011-R6A-SM-3NB3G GTEx Tissue Sample Gene Expression Profiles 1.0 0.913796 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF160 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13897 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 1.0723 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anion binding GO Molecular Function Annotations 2025 1.0 null GSE132759_4_v_5_fgfr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null FADS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17728 REST_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM4A ENCODE Transcription Factor Targets 1.0 null CCDC107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11529 GTEX-QVJO-0011-R8A-SM-447C7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.893124 GSE142684_0_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null lateral part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89275 NCIH146 CCLE Cell Line Gene Expression Profiles 1.0 2.01859 REST_Panc1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1914 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC1A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02413 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NB69 DepMap CRISPR Gene Dependency 1.0 2.22874 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00474 CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Craniopharyngioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.062 GTEX-WL46-0011-R11A-SM-3MJFT GTEx Tissue Sample Gene Expression Profiles 1.0 1.67524 metencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.89924 CACTIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15517 H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KG1C CCLE Cell Line Gene Expression Profiles -1.0 -1.48802 HMV-II COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-Q2AG-0011-R7A-SM-2HMJP GTEx Tissue Sample Gene Expression Profiles 1.0 0.837543 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GSE144231_6_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE115542_2_v_3_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null biological_process GO Biological Process Annotations 2015 1.0 null OIP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17955 r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00447 SCC4 DepMap CRISPR Gene Dependency 1.0 2.93396 DNAJA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1059 C19orf73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67323 GSE138939_2_v_3_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16007 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RQ-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6567 IRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32762 rhombomere 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55101 SNU738 CCLE Cell Line Gene CNV Profiles 1.0 2.13728 H3K27me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.093326 r2 part of the ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2968 H4K20me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE219195_4_v_2_rbm12_human RummaGEO Gene Perturbation Signatures -1.0 null GSE210101,GSE210114_1_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null PAWR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13426 TE-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles 1.0 0.931136 SGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80324 MHH-PREB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null r1 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36117 REST ChEA Transcription Factor Targets 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.18061 COLO-792 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE144231_2_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.225144 NCI-H358 COSMIC Cell Line Gene Mutation Profiles 1.0 null ESS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S7SE-0011-R11A-SM-2XCDD GTEx Tissue Sample Gene Expression Profiles 1.0 2.01892 APOBEC3F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12656 KIAA0319L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87175 EGR-1_KO_GDS3607_525_mouse_Retina - 30 Days (POST-NATAL) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SCARA5_Down Expression_GSE32323_611_human_Colorectal Cancer Cell lines GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58674 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null DMS79 CCLE Cell Line Gene Expression Profiles 1.0 2.20365 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null REST_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-98 TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 EPS15L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85218 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GOLM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63961 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.73639 GPATCH11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86556 SCN1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1155 GSE210682_0_v_1_methadone_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-Q2AG-0011-R10A-SM-2HMLA GTEx Tissue Sample Gene Expression Profiles 1.0 1.32582 D502MG DepMap CRISPR Gene Dependency 1.0 2.05555 GTEX-X585-0011-R5A-SM-46MVI GTEx Tissue Sample Gene Expression Profiles 1.0 0.902271 hsa-miR-4778-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.026857 GSE92457_9_v_12_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null ANKRD13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59421 SERINC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59355 PPP6R3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28427 HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RBM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84485 anteroventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18602 CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K18ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FBXO38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57922 GTEX-RVPU-0011-R10A-SM-2XCAH GTEx Tissue Sample Gene Expression Profiles 1.0 1.09596 HDMYZ DepMap CRISPR Gene Dependency 1.0 2.23254 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11101 Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.095 FOXA1 ENCODE Transcription Factor Targets 1.0 null membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 RAGE_knockout_267_GDS3755 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.48009 GTEX-R55E-0011-R8A-SM-2TC66 GTEx Tissue Sample Gene Expression Profiles 1.0 0.831072 NY COSMIC Cell Line Gene Mutation Profiles 1.0 null MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4276 eb-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.12571 MYC ChEA Transcription Factor Targets 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null REST_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37717 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.75462 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GMEB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12045 CAOV4 DepMap CRISPR Gene Dependency 1.0 6.90431 DBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59702 H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CALM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19596 superficial stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14818 ENGASE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46454 GSE171352_2_v_3_glucagon_human RummaGEO Drug Perturbation Signatures -1.0 null r2 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3884 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null binding GO Molecular Function Annotations 2015 1.0 null GSE151829,GSE151831_7_v_8_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null rostromedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14618 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.57306 GSE157555,GSE157556_3_v_2_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-P44H-0011-R8A-SM-2XCEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.01042 RARA::RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.0399 DLX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73129 GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.14991 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19849 hsa-miR-1305 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GSE153836_11_v_9_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null OVMIU DepMap CRISPR Gene Dependency 1.0 2.91407 GSE200430_1_v_0_sema3d_human RummaGEO Gene Perturbation Signatures -1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100651_FWM_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.21436 TOMM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46643 BEN CCLE Cell Line Gene CNV Profiles 1.0 1.72663 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01301 NCI-N87 COSMIC Cell Line Gene Mutation Profiles 1.0 null TMEM175 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92331 TLX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76489 SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05034 dorsal part of alar p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22355 ZNF329 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25489 RIGI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11081 SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Orbital area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.97873 RNF38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90731 globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35983 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19269 GTEX-RU72-2926-SM-2TF66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.94746 ANAPC15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96688 GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles 1.0 1.92854 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null HCA-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87021 Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NAB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15982 NCI-H838 COSMIC Cell Line Gene Mutation Profiles 1.0 null DU145 DepMap CRISPR Gene Dependency 1.0 2.39225 phosphatidylinositol bisphosphate binding GO Molecular Function Annotations 2025 1.0 null LHX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60777 TK COSMIC Cell Line Gene Mutation Profiles 1.0 null 22RV1 CCLE Cell Line Gene Expression Profiles 1.0 1.51239 Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40802 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.03515 ZBTB7A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AP-4 MotifMap Predicted Transcription Factor Targets 1.0 null Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.34837 superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55982 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1043 AR-35650195-DSRCT-HUMAN-MESENCHYMAL-SARCOMA ChEA Transcription Factor Targets 2022 1.0 null 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.52531 Globus pallidus, internal segment Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25136 KYSE-510 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04581 NB1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DOT1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55636 YD38 DepMap CRISPR Gene Dependency 1.0 2.99005 KNTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27656 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05808 GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.854884 ChIP_REST_18959480 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null lung TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066673 PMC11252405-41467_2024_50426_MOESM4_ESM.xlsx-Fig_S4c-CTCF_CTCF Rummagene Transcription Factor Associations 2026 1.0 null MRI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57565 STK26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17161 cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.085938 Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100532_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.03036 Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.17957 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Zic3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.0384 Simple lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55584 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null isthmic portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28682 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.91376 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null SBDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86424 globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40276 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SE-0011-R10A-SM-2XCDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.23627 hsa-miR-3907 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 PPIF_KO_GSE23028_45_mouse_heart (8 wk) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null mRNA_MYOD1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE115542_5_v_4_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.00876 VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44051 PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.993828 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828837 GSE171401_1_v_2_adnp_mouse RummaGEO Gene Perturbation Signatures -1.0 null OGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61438 Lobules IV-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07031 Spherical high-density lipoprotein particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.5 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.65045 GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27023 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.30123 Perturb_12544_KO_Ctnnb1_SRP194249 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.2183 SUCLA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02603