association	dataset	threshold value	standardized value
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4531
core-binding factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.25
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7384
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83198
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147601
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S12-ZNF384_DiffExprGene-Unnamed_1_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
496100561_PCx_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02071
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31662
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6241
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1718
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SERBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39922
UFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4363
MCF7_Abexinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110265
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
Honey	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.496
MEF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17078
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92923
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8758
A549_MK-5108_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110107
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24099
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_CUDC-907_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015463
GSE216757_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Trichostatin A_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147093
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7585
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6075
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121741
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01351
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1067
PMC7618435-EMS211310-supplement-Table_S1.xlsx-C2-HSC_ELP_NR5A1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10863010-media-2.xlsx-ST18-Unnamed_4_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27219
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-f_CEBPA_DEGs-Gene_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0213
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4165364-13059_2014_406_MOESM5_ESM.xls-Supp_Dataset_3-SUPPLEMENTARY_DATASET_3_AML3_AzaC_WIMSi_246_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11174
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
MCM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08897
PMC11461876-42003_2024_6975_MOESM5_ESM.xlsx-Supplementary_Data_3-Supplementary_Data_3_Differentially_Expressed_Genes_HSE_THP1_UV_Vs_HSE_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50145
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3363
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37791
BSG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06115
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37741
HAUS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30281
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Quisinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146299
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8181
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Abexinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171446
A549_Abexinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165453
MCF7_CUDC-907_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0075676
PMC12532594-41380_2025_3119_MOESM1_ESM.pdf-154-VAX2_VAX2	Rummagene Transcription Factor Associations 2026	1.0	null
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18362
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE86507,GSE86509_3_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_10_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Belinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00890248
A549_SRT3025 HCl_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.012151
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04244
GSE234155_7_v_1_nfix_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16164
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4068
RSF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
PMC10863010-media-2.xlsx-ST18-Unnamed_3_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23412
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ENSG_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PSENEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25461
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1433
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hermaphroditism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00673
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Diamine N-acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.807
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53684
interleukin-7 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Givinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00758903
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.942
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2363
K562_Quisinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168469
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12284
DCAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72686
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11094182-41408_2024_1061_MOESM18_ESM.xlsx-S17_TP53_genes_signatures-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229671,GSE229673_0_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Oral squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
MCF7_AR-42_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00714603
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69115
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06447
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Panobinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00846801
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40564
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28993
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72662
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.9817
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39389
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5408
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016576
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Nintedanib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165708
GSE134693_0_v_1_msr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20396
GSE160817_3_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21188
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43918
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Abexinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00721704
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26224
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Patupilone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148797
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65082
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114992,GSE114993_1_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.865
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2672
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21943
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6C-Table_S6C_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_PRAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50355
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_MLN8054_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184381
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53285
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133516_5_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44501
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6515
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38497
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Crizotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153109
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11294
GSE182680,GSE182683_5_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Panobinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143969
MCF7_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00812155
MCF7_M344_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00967017
PEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40591
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148657_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE84462,GSE84762_2_v_7_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.143
SRD5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02544
HMGCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17145
C18orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23299
Naive CD8+ T cell_Peripheral blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26869
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.132
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-THP-1_MLL-AF9_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09133
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6145
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.324
Mixed phenotype acute leukemia, T/myeloid	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1254
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF521	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81436
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S11-DUX4_DiffExprGene-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
MCF7_Belinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0100449
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3135
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6
SUPT5H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.1279
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56319
A549_CUDC-907_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176836
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9061
P2RX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14727
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_AR-42_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00779795
CDK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60087
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216757_0_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00038
GSE142994_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4292
PMC11542230-12985_2024_2548_MOESM4_ESM.xlsx-MR_results-exposure_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
A549_Pirarubicin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012194
GSE200897_1_v_0_pold1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8109
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
IFFO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65541
RAB11FIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37018
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2478
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
USP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16157
RBMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71657
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8292
GSE120612_4_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Quisinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129018
A549_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212316
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.8681
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Ruxolitinib_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122363
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39447
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.309
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89991
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100442_PCx_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01564
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_GSK1070916_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00913254
GSE142684_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.42989
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5349
PMC12646413-ppat.1013702.s009.pdf-3-KDM2A_KDM2A	Rummagene Transcription Factor Associations 2026	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4641
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15138
MCF7_Pracinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00866995
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Givinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153238
PMC3728595-srep02327-s1.pdf-1629-ZNF181_ZNF181	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-334-TET1_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48983
B-lymphoblastic leukemia/lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
A549_Glesatinib(MGCD265)_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130287
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Resminostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00780092
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Monocyte_Fetal kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EIF3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55363
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68759
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.079
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FZD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23404
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2981
A549_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165075
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-Unnamed_0_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24113
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Unnamed_3_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39625
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4942
GSE160817_3_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173307,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2628
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3525
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6982
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92253
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Panobinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00554111
A549_BMS-536924_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121574
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3707
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.195
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Givinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00736928
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20891
FNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24404
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0988
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103124_2_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180304_3_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Dacinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113288
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54872
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Fasudil_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134272
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25459
A549_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015565
A549_M344_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00894258
TSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2025
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.101
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62791
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tucidinostat_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156695
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2382
A549_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139813
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59378
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54774
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9853
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04662
A549_Tacedinaline_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125362
Childhood leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
PMC11991920-41556_2025_1639_MOESM3_ESM.xlsx-DEGs_MI_vs_Ctrl_HSCs_padj0_1-gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6477
PMC12678582-41698_2025_1153_MOESM5_ESM.xlsx-Sheet1-Common_genes_between_OVCA420-ZNF217_and_MCF7_157_965_1122_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41831
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5771
A549_M344_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147625
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4923
PMC11588066-pnas.2410331121.sapp.pdf-137-SMAD1_SMAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246335_4_v_5_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34266
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44205
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.2258
HSD17B12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21308
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4879
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148658_1_v_0_six6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20131
A549_Hesperadin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112208
A549_SGI-1776 free base_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0104998
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11815
GSE160817_2_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
GSE160817_0_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.316
PMC9038526-mmc1.xlsx-postCOVID_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2543
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3456
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39506
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05357
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1657
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31055
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56961
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_13_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5821
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8127
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24482
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T4B_BATF3_upreg_padj_0_01-Gene_Name_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00709
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-gene_name_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8346
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_BMS-911543_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124471
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55004
Thoracic thymus_CT1_CD4+ T single positive thymocyte	HuBMAP ASCT+B Annotations	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34493
A549_CUDC-907_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167263
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Zileuton_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155598
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Nintedanib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00990014
MCF7_Panobinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00566825
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0863
RPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69344
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1271
PMC12612227-41523_2025_836_MOESM1_ESM.pdf-43-ZNF699_ZNF699	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6219
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229580_0_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44935
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tucidinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129434
A549_Pracinostat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144214
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27281
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.195
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0361
GSE158431_5_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.661
A549_Entinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192827
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50018
ACTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03022
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10248509-Data_Sheet_5.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7391
POLR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2642
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
A549_MK-5108_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013285
PKNOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34505
GSE160817_2_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3152
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM41A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37989
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6729
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00604
MCF7_Belinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137424
A549_PHA-680632_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110172
Childhood acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Thoracic thymus_CT1_CD4+ T single positive thymocyte	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85145
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7616
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8007
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27648
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2753
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9399107-41467_2022_32627_MOESM6_ESM.xlsx-20_T-cell_subsets-gene_name_CD8_C1_LEF1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34606
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9692
ZNF157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68573
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
GSE111247_0_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
GSE173810_4_v_6_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PACS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20942
A549_Tacedinaline_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158336
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0293
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5571
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02657
A549_AR-42_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00977311
A549_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137932
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65296
GSE156708_1_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Abexinostat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0109352
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99675
CMTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13749
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10787250-BLOODA_ADV-2022-008899-mmc1.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_commonly_up-_or_downregulated_in_CBFA2T3_GLIS2_leukemia_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07467
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47344
MCF7_Abexinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00868195
GSE81193_0_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46374
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12354852-41467_2025_62818_MOESM3_ESM.xlsx-Sup_Data_10-Differentially_expressed_genes_in_TAF6L_KD_vs_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Pracinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00570784
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06348
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5727
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98385
GSE114992,GSE114993_0_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
PMC5794192-ppat.1006868.s001.xlsx-S1B_Table-S1B_Table_Differentially_expressed_genes_between_IRF8-sg2_and_NC_cell_lines_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP6R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29496
Scape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231829_0_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115645
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9904760-elife-79363-supp2.xlsx-MDS1-Gene_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13611
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9104
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04357
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
C10orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11061
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5252
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100553_TCx_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04131
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29107
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1703
PMC4165364-13059_2014_406_MOESM5_ESM.xls-Supp_Dataset_1-SUPPLEMENTARY_DATASET_1_AML3_AzaC_SigDiff_1147_Note_to_reviewers_-_view_these_files_as_xls_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.197
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_12_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
A549_TAK-901_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174137
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43852
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.195
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE217201_1_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Pracinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171579
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82146
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Dacinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00556072
PMC10657376-41467_2023_43213_MOESM7_ESM.xlsx-DaNs_EBF1-Unnamed_6_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15384
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Alisertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112449
CIRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27192
ARL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30756
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24576
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34856
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20529
TMEM129	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82161
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39934
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9394
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.413
A549_AMG-900_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0104018
PMC12659123-12864_2025_12285_MOESM12_ESM.xlsx-Table_S12-Table_S12_Differentially_expressed_genes_after_SPI1_knockdown_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
MCF7_Panobinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0063967
PGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12741
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10725
A549_AR-42_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204642
A549_SNS-314 Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0216532
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27397
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38307
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Dacinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130476
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12027
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Tucidinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177492
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5688
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02571
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_AR-42_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00924297
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73105
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19194
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11143203-41422_2024_945_MOESM14_ESM.pdf-3-STAT3_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null