association dataset threshold value standardized value demonstrates GeneRIF Biological Term Annotations 1.0 null FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.7983 Dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.099 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease progression to geographic atrophy form in age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.5 GNPDA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57553 GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 1.40726 GTEX-OIZH-0726-SM-3NB1I GTEx Tissue Sample Gene Expression Profiles 1.0 0.923674 GTEX-UPIC-1626-SM-4IHKT GTEx Tissue Sample Gene Expression Profiles 1.0 0.835769 Photoreceptor inner segment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.906 PLD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16858 PAX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54122 Hypothyroidism DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.168 attributes GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null factors GeneRIF Biological Term Annotations 1.0 null showing GeneRIF Biological Term Annotations 1.0 null outcome GeneRIF Biological Term Annotations 1.0 null DPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98231 respectively GeneRIF Biological Term Annotations 1.0 null angiography GeneRIF Biological Term Annotations 1.0 null GTEX-Q734-0726-SM-48TZP GTEx Tissue Sample Gene Expression Profiles 1.0 1.41461 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null G protein-coupled receptor heterodimeric complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.638 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.61093 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 2.04159 lymphoma GWASdb SNP-Disease Associations 1.0 0.95488 presence GeneRIF Biological Term Annotations 1.0 null Lens nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.69 independent GeneRIF Biological Term Annotations 1.0 null HSD3B7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.10007 features GeneRIF Biological Term Annotations 1.0 null diseases in twins; macular degeneration; retinal drusen GAD Gene-Disease Associations 1.0 null signal GeneRIF Biological Term Annotations 1.0 null HMGA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98031 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.177849 serum GeneRIF Biological Term Annotations 1.0 null Myopia, Degenerative HuGE Navigator Gene-Phenotype Associations 1.0 null Phacogenic glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.485 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4535 arms2loc387715 GeneRIF Biological Term Annotations 1.0 null HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38559 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15768 subjects GeneRIF Biological Term Annotations 1.0 null high-density lipoprotein particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.91 level GeneRIF Biological Term Annotations 1.0 null suffering GeneRIF Biological Term Annotations 1.0 null GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.64323 Prostate adenocarcinoma_PRAD_TCGA-G9-6329-01A-13R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100497_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.93845 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ata GeneRIF Biological Term Annotations 1.0 null predict GeneRIF Biological Term Annotations 1.0 null RAB6D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27261 typical GeneRIF Biological Term Annotations 1.0 null stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1726 Primary immunodeficiency disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.158 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.1214 FXR MotifMap Predicted Transcription Factor Targets 1.0 null SAMD4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23147 provide GeneRIF Biological Term Annotations 1.0 null Age-related macular degeneration (CNV vs. GA) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.31549 CXXC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30564 PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null total GeneRIF Biological Term Annotations 1.0 null risks GeneRIF Biological Term Annotations 1.0 null nucleotide GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8205-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retinopathy of prematurity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.335 overnutrition GWASdb SNP-Disease Associations 1.0 0.463999 medial parabrachial nucleus,right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.876493 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A633-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null individuals GeneRIF Biological Term Annotations 1.0 null Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903627 TMSB15A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01922 Toxic maculopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.597 HOXB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32092 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06564 Acute Myeloid Leukemia_LAML_TCGA-AB-2836-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr10_122388748_A_G_b38 GTEx eQTL 2025 1.0 3.22704 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.89646 lung disease GWASdb SNP-Disease Associations 1.0 0.25668 FHDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83137 Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null icSARA deltaORF6_3Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.3341 Diabetic Angiopathies HuGE Navigator Gene-Phenotype Associations 1.0 null bilateral GeneRIF Biological Term Annotations 1.0 null demonstrated GeneRIF Biological Term Annotations 1.0 null histoplasmosis GeneRIF Biological Term Annotations 1.0 null SMAD2/3-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-WYVS-1626-SM-3NM9R GTEx Tissue Sample Gene Expression Profiles 1.0 0.987405 AP-4 MotifMap Predicted Transcription Factor Targets 1.0 null Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.36 neoplasm GWASdb SNP-Phenotype Associations 1.0 0.054043 rmd GeneRIF Biological Term Annotations 1.0 null NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21362 hsa-miR-4741 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.044 Endophthalmitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.759 Heart disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.714 posterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.76631 types GeneRIF Biological Term Annotations 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 age GeneRIF Biological Term Annotations 1.0 null PLCB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45086 epidemiologic GeneRIF Biological Term Annotations 1.0 null ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4371 european GeneRIF Biological Term Annotations 1.0 null B3GALNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25098 GTEX-XUJ4-2526-SM-4BOO4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.82838 Lung squamous cell carcinoma_LUSC_TCGA-98-A53B-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UMUC1 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 Sarcoma_SARC_TCGA-WK-A8XS-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null higher GeneRIF Biological Term Annotations 1.0 null SORT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2903 nested GeneRIF Biological Term Annotations 1.0 null interactions GeneRIF Biological Term Annotations 1.0 null Reticular Pseudodrusen DisGeNET Gene-Disease Associations 1.0 null HHEX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27972 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54695 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.932093 Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y5-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KAT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1603 CLN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27907 Vitreous disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.706 Lipid metabolism disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.019 rs754203 GeneRIF Biological Term Annotations 1.0 null GSE185865_0_v_1_celf6_human RummaGEO Gene Perturbation Signatures -1.0 null Age related macular degeneration DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 GTEX-RTLS-2426-SM-46MUO GTEx Tissue Sample Gene Expression Profiles 1.0 0.995824 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.91971 cigarette GeneRIF Biological Term Annotations 1.0 null Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.877 group GeneRIF Biological Term Annotations 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null confers GeneRIF Biological Term Annotations 1.0 null vegfa GeneRIF Biological Term Annotations 1.0 null bevacizumab GeneRIF Biological Term Annotations 1.0 null type GeneRIF Biological Term Annotations 1.0 null Optic Disk Drusen HuGE Navigator Gene-Phenotype Associations 1.0 null four GeneRIF Biological Term Annotations 1.0 null GTEX-XLM4-1026-SM-4AT51 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0732 Age-related macular degeneration (extreme sampling) GWAS Catalog SNP-Phenotype Associations 1.0 1.26915 Glycogen Storage Disease DisGeNET Gene-Disease Associations 1.0 null Retinal Neovascularization HuGE Navigator Gene-Phenotype Associations 1.0 null Choroid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 3.102 TMEM143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05978 Integument TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 previous GeneRIF Biological Term Annotations 1.0 null Vascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.202 FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 88.7574 CAOV4 DepMap CRISPR Gene Dependency 1.0 5.44149 Macula lutea TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.17 peripheral vascular diseases GAD Gene-Disease Associations 1.0 null macular degeneration; neovascularization, pathologic GAD Gene-Disease Associations 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null smoke GeneRIF Biological Term Annotations 1.0 null arms2htra1 GeneRIF Biological Term Annotations 1.0 null joint GeneRIF Biological Term Annotations 1.0 null exudative GeneRIF Biological Term Annotations 1.0 null derived GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5364-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Familial (Fpah) DisGeNET Gene-Disease Associations 1.0 null TOV21G CCLE Cell Line Gene CNV Profiles 1.0 1.53356 Choroiditis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.276 VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26871 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22647 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2911 india GeneRIF Biological Term Annotations 1.0 null GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 1.1342 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.87209 GTEX-P4PQ-0426-SM-3NMCI GTEx Tissue Sample Gene Expression Profiles 1.0 0.837994 TAFAZZIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93967 three GeneRIF Biological Term Annotations 1.0 null support GeneRIF Biological Term Annotations 1.0 null GTEX-RU72-1026-SM-46MUG GTEx Tissue Sample Gene Expression Profiles 1.0 0.848305 cone-rod dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.274 Ocular hyperemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.301 Telodendria COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.605 p636x106 GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Atrophic DisGeNET Gene-Phenotype Associations 1.0 null HT144 DepMap CRISPR Gene Dependency 1.0 3.41611 PDIK1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2561 Glomerulonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.2 C2CD4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27302 superior parietal lobule, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.958584 RAPGEFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52986 provides GeneRIF Biological Term Annotations 1.0 null HOXD12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.989 GTEX-TMZS-0126-SM-3DB9Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.843444 Retinal rod TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.007 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4833-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null statistical GeneRIF Biological Term Annotations 1.0 null ENHO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81647 GTEX-SNOS-1426-SM-32PLY GTEx Tissue Sample Gene Expression Profiles 1.0 0.918989 Retinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.295 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.45136 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949558 SYN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22533 Disease Susceptibility HuGE Navigator Gene-Phenotype Associations 1.0 null Retinal stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.439 Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null y402h GeneRIF Biological Term Annotations 1.0 null size GeneRIF Biological Term Annotations 1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 2.40533 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADGRG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79734 Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61244 greater GeneRIF Biological Term Annotations 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.79631 intermediate-density lipoprotein particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.646 HCT116 CCLE Cell Line Gene CNV Profiles 1.0 1.646 NR3C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94227 acuity GeneRIF Biological Term Annotations 1.0 null especially GeneRIF Biological Term Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AX-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HINFP_02_36 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 5.04439 egyptian GeneRIF Biological Term Annotations 1.0 null GTEX-O5YT-0426-SM-3MJHD GTEx Tissue Sample Gene Expression Profiles 1.0 0.991162 SLC25A45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92729 none GeneRIF Biological Term Annotations 1.0 null Inner plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.682 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09504 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2994 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DG-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JW-1726-SM-3GADN GTEx Tissue Sample Gene Expression Profiles 1.0 1.26736 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.871653 SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2658 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.177 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.47895 Extraocular muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.58 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4728-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.932093 G0S2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30907 Disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 Neovascular glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 GTEX-XAJ8-0326-SM-47JYI GTEx Tissue Sample Gene Expression Profiles 1.0 1.15191 concur GeneRIF Biological Term Annotations 1.0 null Peripheral vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.538 HCC1395 CCLE Cell Line Gene CNV Profiles 1.0 1.3617 GTEX-T6MO-1126-SM-4DM5D GTEx Tissue Sample Gene Expression Profiles 1.0 0.990713 rs11200638 GeneRIF Biological Term Annotations 1.0 null Photoreceptor cell cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.458 496100297_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04608 ZBTB41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15703 equal GeneRIF Biological Term Annotations 1.0 null Central nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.202 Nutrition disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.641 ZNF512 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86881 MDAMB453 CCLE Cell Line Gene CNV Profiles 1.0 1.54971 KYAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30474 major GeneRIF Biological Term Annotations 1.0 null ZNF93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7929 GTEX-XBEC-1526-SM-4AT68 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03406 PMC8200556__F2 PFOCR Pathway Figure Associations 2024 1.0 null Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.85 degenerationamd GeneRIF Biological Term Annotations 1.0 null GTEX-PWOO-2426-SM-2S1OV GTEx Tissue Sample Gene Expression Profiles 1.0 1.1024 Posterior uveitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 hsa-miR-4715-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 those GeneRIF Biological Term Annotations 1.0 null GTEX-PWN1-0126-SM-2I3FK GTEx Tissue Sample Gene Expression Profiles 1.0 0.973138 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.863877 PMC11652211-Table1.docx-0-SMYD3_SMYD3 Rummagene Transcription Factor Associations 2026 1.0 null trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05155 Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caucasians GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-A46R-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.827663 variant GeneRIF Biological Term Annotations 1.0 null pai1 GeneRIF Biological Term Annotations 1.0 null PARP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61415 GTEX-UPIC-1526-SM-4IHLU GTEx Tissue Sample Gene Expression Profiles 1.0 1.20308 tissue homeostasis GO Biological Process Annotations 2015 1.0 null MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05743 E2F4 ENCODE Transcription Factor Targets 1.0 null GTEX-UPK5-1326-SM-4IHLE GTEx Tissue Sample Gene Expression Profiles 1.0 1.00531 detected GeneRIF Biological Term Annotations 1.0 null ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7337 myopia GeneRIF Biological Term Annotations 1.0 null Retinal vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.356 useful GeneRIF Biological Term Annotations 1.0 null PWWP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7444 Prostate adenocarcinoma_PRAD_TCGA-VP-A879-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4575 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.45928 knowledge GeneRIF Biological Term Annotations 1.0 null SNX33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93692 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null SLAIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69929 Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ethnic GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.543 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.94773 GTEX-O5YV-0226-SM-48TBY GTEx Tissue Sample Gene Expression Profiles 1.0 1.06378 neoplasm by anatomical site GWASdb SNP-Phenotype Associations 1.0 0.056002 fh62 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.208 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1789 Retinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40465 HCT 116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72503 ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5492 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881828 ZNF606 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19304 MED15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7141 Ciliary body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.327 GTEX-RWSA-0126-SM-2XCBB GTEx Tissue Sample Gene Expression Profiles 1.0 1.2339 oa1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.65 although GeneRIF Biological Term Annotations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null muscle GTEx Tissue Gene Expression Profiles -1.0 -1.13793 PANC1 CCLE Cell Line Gene CNV Profiles 1.0 1.33119 turkish GeneRIF Biological Term Annotations 1.0 null GTEX-W5WG-1326-SM-4LMI9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.878054 Diabetes DisGeNET Gene-Disease Associations 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5964-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRKCSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78487 SNN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34111 Lung adenocarcinoma_LUAD_TCGA-67-6215-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null NCAN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70518 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VPS26A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44943 purpose GeneRIF Biological Term Annotations 1.0 null leukemia GWASdb SNP-Disease Associations 1.0 0.95488 Autosomal dominant disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18122 CCC5 DepMap CRISPR Gene Dependency 1.0 5.49701 Melanosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.643 GTEX-OHPK-2426-SM-3MJGH GTEx Tissue Sample Gene Expression Profiles 1.0 1.08427 Iminoglycinuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.002 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.97814 PMC11073998-41375_2024_2235_MOESM9_ESM.xlsx-THP1_phosphoproteome-Unnamed_2_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null E2F4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11386 V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.50029 genetic GeneRIF Biological Term Annotations 1.0 null Anterior chamber of the eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.953 IDE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82469 GTEX-U3ZH-0326-SM-3DB7A GTEx Tissue Sample Gene Expression Profiles 1.0 0.948291 UQCR10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57224 systemic GeneRIF Biological Term Annotations 1.0 null loc387715arms2 GeneRIF Biological Term Annotations 1.0 null KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15768 rather GeneRIF Biological Term Annotations 1.0 null Photoreceptor disc membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.762 deletioninsertion GeneRIF Biological Term Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VN-01A-21R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null eye disease GWASdb SNP-Disease Associations 1.0 1.99945 hungarian GeneRIF Biological Term Annotations 1.0 null TMEM30A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57858 Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null bilaterality GeneRIF Biological Term Annotations 1.0 null significant GeneRIF Biological Term Annotations 1.0 null RBM23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23082 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WO-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPL41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65165 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PABPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21547 Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851606 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851606 abnormality of skeletal morphology GWASdb SNP-Phenotype Associations 1.0 0.784165 transcript GeneRIF Biological Term Annotations 1.0 null Elastic fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.047 field GeneRIF Biological Term Annotations 1.0 null Ocular hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.378 Inflammatory Bowel Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-5870-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40981 RBMS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59716 BAIAP2L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68041 P3H4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73438 smoked GeneRIF Biological Term Annotations 1.0 null H3K4me1_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mitochondrial GeneRIF Biological Term Annotations 1.0 null there GeneRIF Biological Term Annotations 1.0 null hsa-miR-4459 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 PMC10290283-biol-2022-0622-sm3.pdf-459-OVOL2_OVOL2 Rummagene Transcription Factor Associations 2026 1.0 null HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.82815 different GeneRIF Biological Term Annotations 1.0 null Retinal Angiomatous Proliferation DisGeNET Gene-Disease Associations 1.0 null Retinal cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.357 alzheimers GeneRIF Biological Term Annotations 1.0 null choroid GeneRIF Biological Term Annotations 1.0 null GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.40544 ELL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15238 Hypercholesterolemia HuGE Navigator Gene-Phenotype Associations 1.0 null GSE201877_1_v_0_yap1_human RummaGEO Gene Perturbation Signatures -1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.243 Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Genetic disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 reticular GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XK-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acids GeneRIF Biological Term Annotations 1.0 null crp GeneRIF Biological Term Annotations 1.0 null Hypertension DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.908 shown GeneRIF Biological Term Annotations 1.0 null Retinoblastoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.82 late GeneRIF Biological Term Annotations 1.0 null NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21804 RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5494 MICU2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81631 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.22013 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69057 SULF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89262 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.92302 Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.769 share GeneRIF Biological Term Annotations 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 2.2214 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18143 Sorsby's fundus dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.117 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.83917 GTEX-QEL4-0526-SM-3GIJ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16303 Peripheral Vascular Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null HIP1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80264 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881828 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.748 treatment GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZN-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XQ8I-0826-SM-4BOOE GTEx Tissue Sample Gene Expression Profiles 1.0 0.883773 classic GeneRIF Biological Term Annotations 1.0 null severity GeneRIF Biological Term Annotations 1.0 null Retinal Detachment HuGE Navigator Gene-Phenotype Associations 1.0 null Complement component 2 deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.131 SHSY5Y DepMap CRISPR Gene Dependency 1.0 2.95838 benefits GeneRIF Biological Term Annotations 1.0 null hsa-miR-4775 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 MON DepMap CRISPR Gene Dependency 1.0 4.82049 give GeneRIF Biological Term Annotations 1.0 null relate GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null open-angle glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.668 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 2.36183 MRPL35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88123 Macular Degeneration DisGeNET Gene-Disease Associations 1.0 null t1277c GeneRIF Biological Term Annotations 1.0 null PLEKHA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89513 Age-related macular degeneration (CNV vs. GA) GWAS Catalog SNP-Phenotype Associations 1.0 0.77375 unfavorable GeneRIF Biological Term Annotations 1.0 null notion GeneRIF Biological Term Annotations 1.0 null Endocrine system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.168 Glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.203 age-related maculopathy GAD Gene-Disease Associations 1.0 null IVD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30347 inner CP in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.940798 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null polyadenylation GeneRIF Biological Term Annotations 1.0 null HCC1359 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44088 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null choroid diseases; peripheral vascular diseases GAD Gene-Disease Associations 1.0 null ors GeneRIF Biological Term Annotations 1.0 null CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3973 C99 DepMap CRISPR Gene Dependency 1.0 6.70708 status GeneRIF Biological Term Annotations 1.0 null index GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LRRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28007 BCDIN3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19887 PTTG1IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.952 hsa-miR-296-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Vein disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.38 retina homeostasis GO Biological Process Annotations 2025 1.0 null Partial central choroid dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.305 indel GeneRIF Biological Term Annotations 1.0 null D-407 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.605 Drusen DisGeNET Gene-Disease Associations 1.0 null they GeneRIF Biological Term Annotations 1.0 null HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851606 rs1061170 GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS21BM CCLE Cell Line Gene CNV Profiles -1.0 -2.07711 age related macular degeneration GWASdb SNP-Disease Associations 1.0 4.56214 CGREF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92742 confirm GeneRIF Biological Term Annotations 1.0 null HOXC10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5919 TUBB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49798 endothelial GeneRIF Biological Term Annotations 1.0 null implicated GeneRIF Biological Term Annotations 1.0 null K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903627 SPRYD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45485 NUGC3 CCLE Cell Line Gene CNV Profiles 1.0 1.54073 hsa-miR-4728-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GTEX-WRHU-1326-SM-4E3K7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.953811 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prevalence GeneRIF Biological Term Annotations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null homeostatic process GO Biological Process Annotations 2015 1.0 null Retinitis pigmentosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.881 KPNYN CCLE Cell Line Gene CNV Profiles -1.0 -1.73828 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plekha1arms2htra1 GeneRIF Biological Term Annotations 1.0 null TSFM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29092 MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852436 SF126 DepMap CRISPR Gene Dependency 1.0 2.2975 combine GeneRIF Biological Term Annotations 1.0 null riskconferring GeneRIF Biological Term Annotations 1.0 null formulation GeneRIF Biological Term Annotations 1.0 null specific GeneRIF Biological Term Annotations 1.0 null GTEX-T5JW-0426-SM-4DM7M GTEx Tissue Sample Gene Expression Profiles 1.0 0.831521 hsa-miR-3119 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 hsa-miR-4428 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 DNAJB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99789 CENPO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45888 confer GeneRIF Biological Term Annotations 1.0 null subtype GeneRIF Biological Term Annotations 1.0 null CDC42SE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33897 Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKNMC CCLE Cell Line Gene CNV Profiles -1.0 -1.63715 CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KP1N DepMap CRISPR Gene Dependency 1.0 3.32218 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19427 GTEX-UJMC-0426-SM-4IHJF GTEx Tissue Sample Gene Expression Profiles 1.0 1.04701 atrophic GeneRIF Biological Term Annotations 1.0 null Ischemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.193 fhr1 GeneRIF Biological Term Annotations 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8416-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null modulate GeneRIF Biological Term Annotations 1.0 null TTLL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47942 NDUFB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75053 younger GeneRIF Biological Term Annotations 1.0 null GTEX-UPIC-1826-SM-4IHKC GTEx Tissue Sample Gene Expression Profiles 1.0 1.08974 Lung adenocarcinoma_LUAD_TCGA-91-8497-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macular degeneration GWASdb SNP-Phenotype Associations 1.0 4.73758 Globe disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.757 subgroups GeneRIF Biological Term Annotations 1.0 null Eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.187 protective GeneRIF Biological Term Annotations 1.0 null central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29946 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.10385 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TADA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69777 central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52872 abnormality of the macula GWASdb SNP-Phenotype Associations 1.0 4.73758 neovascularization GeneRIF Biological Term Annotations 1.0 null GTEX-WEY5-1926-SM-3GIL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02902 hsa-miR-4477b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4774-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null strongly GeneRIF Biological Term Annotations 1.0 null arms2 GeneRIF Biological Term Annotations 1.0 null RERFGC1B CCLE Cell Line Gene CNV Profiles 1.0 1.77493 incidence GeneRIF Biological Term Annotations 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.66192 Atrophy HuGE Navigator Gene-Phenotype Associations 1.0 null PIGW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83176 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 2.67577 NCIH226 CCLE Cell Line Gene CNV Profiles -1.0 -1.47642 Lung adenocarcinoma_LUAD_TCGA-91-6829-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mainstream GeneRIF Biological Term Annotations 1.0 null STRN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57663 asian GeneRIF Biological Term Annotations 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 GTEX-T5JC-2526-SM-4DM6G GTEx Tissue Sample Gene Expression Profiles 1.0 0.994994 Genetic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 Lens epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.89 Sarcoma_SARC_TCGA-K1-A3PO-11A-12R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZKSCAN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19318 Hereditary retinal dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.985 GTEX-X585-0011-R1B-SM-46MVE GTEx Tissue Sample Gene Expression Profiles 1.0 1.04767 Rectum adenocarcinoma_READ_TCGA-F5-6812-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neovascular GeneRIF Biological Term Annotations 1.0 null carotenoids GeneRIF Biological Term Annotations 1.0 null Kuhnt-Junius degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.114 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903627 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PZ-01A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sense organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Neovascular age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.61549 DNM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81683 Hip dbGAP Gene-Trait Associations 1.0 0.238996 estimates GeneRIF Biological Term Annotations 1.0 null HPAFII DepMap CRISPR Gene Dependency 1.0 2.73518 Age-related macular degeneration (CNV) GWAS Catalog SNP-Phenotype Associations 1.0 2.07262 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16861 pathogenesis GeneRIF Biological Term Annotations 1.0 null detect GeneRIF Biological Term Annotations 1.0 null italian GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5332-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2093 ZNF559 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51874 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.985171 SAP18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6787 Choroiditis HuGE Navigator Gene-Phenotype Associations 1.0 null samples GeneRIF Biological Term Annotations 1.0 null spanish GeneRIF Biological Term Annotations 1.0 null Retinal perforation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.437 SDF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81457 Wet Age-Related Macular Degeneration DisGeNET Gene-Disease Associations 1.0 null ZMPSTE24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0245 neutral GeneRIF Biological Term Annotations 1.0 null ACTR3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74825 GTEX-UPIC-0926-SM-4IHLV GTEx Tissue Sample Gene Expression Profiles 1.0 0.918541 GTEX-T2IS-2226-SM-4DM65 GTEx Tissue Sample Gene Expression Profiles 1.0 0.854936 {macular degeneration, age-related, 8} OMIM Gene-Disease Associations 1.0 null negative GeneRIF Biological Term Annotations 1.0 null PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7791 PTGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30306 diabetes, type 2 GAD Gene-Disease Associations 1.0 null thin GeneRIF Biological Term Annotations 1.0 null FASTKD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20835 singlenucleotide GeneRIF Biological Term Annotations 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.79523 cohorts GeneRIF Biological Term Annotations 1.0 null tnfalpha GeneRIF Biological Term Annotations 1.0 null H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null change GeneRIF Biological Term Annotations 1.0 null spite GeneRIF Biological Term Annotations 1.0 null GTEX-P4QS-2026-SM-3NMCG GTEx Tissue Sample Gene Expression Profiles 1.0 0.858133 hsa-miR-1827 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 individual GeneRIF Biological Term Annotations 1.0 null CWC15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61678 while GeneRIF Biological Term Annotations 1.0 null UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66053 unstable GeneRIF Biological Term Annotations 1.0 null Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.957 Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15727 hsa-miR-1226 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 hsa-miR-23c TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 suggestions GeneRIF Biological Term Annotations 1.0 null subfoveal GeneRIF Biological Term Annotations 1.0 null SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8672 japanese GeneRIF Biological Term Annotations 1.0 null posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25549 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90031 ancestry GeneRIF Biological Term Annotations 1.0 null PDXDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5207 MDAMB415 CCLE Cell Line Gene CNV Profiles 1.0 1.98497 THP1 CCLE Cell Line Gene CNV Profiles -1.0 -2.61093 H2BK12ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X2-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null polypoidal GeneRIF Biological Term Annotations 1.0 null Age related macular degeneration 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.567 Cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.021 oxidative GeneRIF Biological Term Annotations 1.0 null whereas GeneRIF Biological Term Annotations 1.0 null immune system cancer GWASdb SNP-Disease Associations 1.0 0.23219 ZNF747 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0199 NB17 DepMap CRISPR Gene Dependency 1.0 2.12322 PLEKHN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.36139 Low tension glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.081 amd GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H1-6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17819 directly GeneRIF Biological Term Annotations 1.0 null highly GeneRIF Biological Term Annotations 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.83461 H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Coronary Artery Disease HuGE Navigator Gene-Phenotype Associations 1.0 null superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16774 serve GeneRIF Biological Term Annotations 1.0 null SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 blind vision; blindness; choroidal neovascularization; macular degeneration GAD Gene-Disease Associations 1.0 null neither GeneRIF Biological Term Annotations 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22394 BMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77752 central GeneRIF Biological Term Annotations 1.0 null Early age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 2025 1.0 10.0 Artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.059 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31136 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.431 Bone inflammation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.204 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59525 PLPP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16145 Myopia HuGE Navigator Gene-Phenotype Associations 1.0 null bmes GeneRIF Biological Term Annotations 1.0 null Color blindness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.009 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7078 GTEX-PLZ4-2826-SM-3P617 GTEx Tissue Sample Gene Expression Profiles 1.0 0.976616 MCAS CCLE Cell Line Gene CNV Profiles 1.0 1.63183 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Panuveitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.099 polish GeneRIF Biological Term Annotations 1.0 null Laterality in neovascular age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 Age related macular degeneration ClinVar Gene-Phenotype Associations 2025 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8403 Lung adenocarcinoma_LUAD_TCGA-62-8397-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.299 EXOSC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90188 GTEX-XOT4-0826-SM-4B66Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.33047 RUNX2 JASPAR Predicted Transcription Factor Targets 1.0 null Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.186 Disease Progression HuGE Navigator Gene-Phenotype Associations 1.0 null Autoimmune thyroiditis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.158 GTEX-N7MS-0011-R1a-SM-2HMJG GTEx Tissue Sample Gene Expression Profiles 1.0 0.944446 haplotypes GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taste HuGE Navigator Gene-Phenotype Associations 1.0 null ERI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.61342 Choroidal Neovascularization HuGE Navigator Gene-Phenotype Associations 1.0 null MKS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51677 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46E-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Interphotoreceptor matrix TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.628 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.485988 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.39 Advanced age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 2025 1.0 10.0 rs112000638 GeneRIF Biological Term Annotations 1.0 null period GeneRIF Biological Term Annotations 1.0 null C6orf120 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39932 Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retinal degeneration DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 abca1 GeneRIF Biological Term Annotations 1.0 null Refractive error GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.22218 variation GeneRIF Biological Term Annotations 1.0 null indocyanine GeneRIF Biological Term Annotations 1.0 null MTMR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62397 Inner nuclear layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.88 Microvillus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.277 GTEX-QVJO-0011-R1A-SM-2S1QI GTEx Tissue Sample Gene Expression Profiles 1.0 0.885031 ERA-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null wildtype GeneRIF Biological Term Annotations 1.0 null related GeneRIF Biological Term Annotations 1.0 null metaanalyses GeneRIF Biological Term Annotations 1.0 null pathology GeneRIF Biological Term Annotations 1.0 null abnormality of the posterior segment of the eye GWASdb SNP-Phenotype Associations 1.0 2.37396 MITF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4591 lower GeneRIF Biological Term Annotations 1.0 null than GeneRIF Biological Term Annotations 1.0 null Horizontal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.665 Macular Degeneration CTD Gene-Disease Associations 1.0 2.88009 Choroidal Vascular Hyperpermeability DisGeNET Gene-Phenotype Associations 1.0 null CIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38548 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.974347 suggesting GeneRIF Biological Term Annotations 1.0 null ACSBG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99536 Senile cataract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.236 allele GeneRIF Biological Term Annotations 1.0 null Alzheimer Disease DisGeNET Gene-Disease Associations 1.0 null NODAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71059 hscrp GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRO-1226-SM-48TDL GTEx Tissue Sample Gene Expression Profiles 1.0 1.15397 isoforms GeneRIF Biological Term Annotations 1.0 null tamd GeneRIF Biological Term Annotations 1.0 null Myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.102 GSE114284_1_v_3_irf1_human RummaGEO Gene Perturbation Signatures 1.0 null HOXC12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2922 SAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5956 outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1965 GTEX-TML8-0926-SM-4DXSJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.949333 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.99369 loxl1 GeneRIF Biological Term Annotations 1.0 null X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.72858 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41077 locus ceruleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04656 roles GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7SF-1326-SM-4AD4P GTEx Tissue Sample Gene Expression Profiles 1.0 1.18089 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09078 Degeneration of macula and posterior pole DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.723 risk GeneRIF Biological Term Annotations 1.0 null werirb1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.983 ZBED1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6184 Venule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.277 hsa-miR-23a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Sensory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 Geographic Atrophy HuGE Navigator Gene-Phenotype Associations 1.0 null PANC0504 DepMap CRISPR Gene Dependency 1.0 2.56788 GJB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04732 Blindness DisGeNET Gene-Phenotype Associations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Histoplasmosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.403 chinese GeneRIF Biological Term Annotations 1.0 null coding GeneRIF Biological Term Annotations 1.0 null Cornea TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.777 p305x108 GeneRIF Biological Term Annotations 1.0 null Retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 3.027 proliferation GeneRIF Biological Term Annotations 1.0 null Eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.97 Choroid Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null seems GeneRIF Biological Term Annotations 1.0 null CLK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92089 ANO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98517 GTEX-RU72-2226-SM-46MUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.09816 rates GeneRIF Biological Term Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3Y4-01A-51R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACADS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72714 FBLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5269 UOK101 CCLE Cell Line Gene CNV Profiles 1.0 1.36797 evident GeneRIF Biological Term Annotations 1.0 null GTEX-UJMC-1026-SM-4IHKN GTEx Tissue Sample Gene Expression Profiles 1.0 1.0142 result GeneRIF Biological Term Annotations 1.0 null membrane GeneRIF Biological Term Annotations 1.0 null CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.15992 cumulative GeneRIF Biological Term Annotations 1.0 null H4K91ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PR cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.191 lower respiratory tract disease GWASdb SNP-Disease Associations 1.0 0.25668 GSE216043_7_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61566 choroid diseases; macular degeneration; peripheral vascular diseases GAD Gene-Disease Associations 1.0 null somewhat GeneRIF Biological Term Annotations 1.0 null choroidal neovascularization; geographic atrophy GAD Gene-Disease Associations 1.0 null persons GeneRIF Biological Term Annotations 1.0 null PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1681 disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.072007 armd GeneRIF Biological Term Annotations 1.0 null HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26842 HBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34311 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.93761 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SM-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plekha1 GeneRIF Biological Term Annotations 1.0 null GTEX-UPIC-0626-SM-4IHK2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03897 CIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30734 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retinal pigment epithelium cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.224 very GeneRIF Biological Term Annotations 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14549 Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cerebrovascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.202 studies GeneRIF Biological Term Annotations 1.0 null Autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.172 Bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.173 PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null anatomical structure homeostasis GO Biological Process Annotations 2015 1.0 null MIDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76037 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14394 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null CC2D1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61403 KLRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9212 Mitochondrion COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19971 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1681 element GeneRIF Biological Term Annotations 1.0 null KAT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90626 LRATD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82559 difference GeneRIF Biological Term Annotations 1.0 null Cone dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.175 additional GeneRIF Biological Term Annotations 1.0 null AFMID CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33076 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09302 snp GeneRIF Biological Term Annotations 1.0 null SUPT11 CCLE Cell Line Gene CNV Profiles -1.0 -1.3519 C10 DepMap CRISPR Gene Dependency 1.0 2.01321 bone disease GWASdb SNP-Disease Associations 1.0 0.148438 IFIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15877 XRCC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31217 ISX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81371 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3944 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.365 GTEX-S341-1626-SM-3K2B8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.29417 PRMT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05195 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54119 GTEX-S32W-2226-SM-2XCAY GTEx Tissue Sample Gene Expression Profiles 1.0 1.12946 Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EDARADD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95107 removing GeneRIF Biological Term Annotations 1.0 null H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Choroidal Neovascularization DisGeNET Gene-Phenotype Associations 1.0 null Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.919 enhanced GeneRIF Biological Term Annotations 1.0 null variants GeneRIF Biological Term Annotations 1.0 null GTEX-RU1J-0826-SM-46MUU GTEx Tissue Sample Gene Expression Profiles 1.0 0.833335 Cranial nerve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.28 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29708 earlier GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null del443ins54 GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-0011-R8A-SM-32QP3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.980623 ZCCHC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99069 rapid GeneRIF Biological Term Annotations 1.0 null YY1 JASPAR Predicted Transcription Factor Targets 1.0 null IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01714 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lymphoma GWASdb SNP-Phenotype Associations 1.0 0.841148 stress GeneRIF Biological Term Annotations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEMA6C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50898 supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.39882 496100372_HIP_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06963 HDAC8_02_51 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.29768 incorporate GeneRIF Biological Term Annotations 1.0 null schemes GeneRIF Biological Term Annotations 1.0 null pattern GeneRIF Biological Term Annotations 1.0 null malondialdehyde GeneRIF Biological Term Annotations 1.0 null WM3772F DepMap CRISPR Gene Dependency 1.0 2.50706 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851606 ZNF599 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81054 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AC-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Epithelium TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-Q2AG-1126-SM-48U1P GTEx Tissue Sample Gene Expression Profiles 1.0 0.832375 Diabetes Mellitus, Type 1 HuGE Navigator Gene-Phenotype Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 2.14205 phenotypes GeneRIF Biological Term Annotations 1.0 null Cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.714 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20826 Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retina homeostasis GO Biological Process Annotations 2023 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Calcinosis HuGE Navigator Gene-Phenotype Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null F11R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0751 GTEX-OHPK-0226-SM-3MJH6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.894965 ESR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65575 Primary systemic mycosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.25 EID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95716 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RI-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null susceptibility GeneRIF Biological Term Annotations 1.0 null FUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71531 pharmacogenetic GeneRIF Biological Term Annotations 1.0 null loc GeneRIF Biological Term Annotations 1.0 null IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54203 Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC Rummagene Transcription Factor Associations 2026 1.0 null investigation GeneRIF Biological Term Annotations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.87084 sensory system disease GWASdb SNP-Disease Associations 1.0 1.85216 young GeneRIF Biological Term Annotations 1.0 null E.F.G complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.719 confirming GeneRIF Biological Term Annotations 1.0 null HAPLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96248 advanced GeneRIF Biological Term Annotations 1.0 null i62v GeneRIF Biological Term Annotations 1.0 null pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22222 equally GeneRIF Biological Term Annotations 1.0 null mesopic GeneRIF Biological Term Annotations 1.0 null Vitreous chamber of the eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.785 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08309 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90031 OC314 DepMap CRISPR Gene Dependency 1.0 6.38364 Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.029 Hereditary choroidal atrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.305 fibrovascular GeneRIF Biological Term Annotations 1.0 null GCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06079 artery GeneRIF Biological Term Annotations 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Eye degenerative disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03946 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.817 DOK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96344 Heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.161 CRY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94589 GTEX-QLQW-1226-SM-2S1Q9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4326 NUPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57271 affected GeneRIF Biological Term Annotations 1.0 null who GeneRIF Biological Term Annotations 1.0 null HDAC6 ENCODE Transcription Factor Targets 1.0 null HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.33325 contributions GeneRIF Biological Term Annotations 1.0 null ranibizumab GeneRIF Biological Term Annotations 1.0 null DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.71 GTEX-PX3G-2426-SM-48TZZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.58552 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plekha1loc387715htra1 GeneRIF Biological Term Annotations 1.0 null SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1429 Cystoid macular edema DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.474 harbored GeneRIF Biological Term Annotations 1.0 null SNU-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11662 LRRC8E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01453 Photoreceptor outer segment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.574 NRIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94459 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H1-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48509 Coronary artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.462 Optic nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.923 complement GeneRIF Biological Term Annotations 1.0 null effects GeneRIF Biological Term Annotations 1.0 null rs10490923 GeneRIF Biological Term Annotations 1.0 null ZNF552 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68176 V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04108 Proliferative diabetic retinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.381 hormone GeneRIF Biological Term Annotations 1.0 null ZNF419 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47005 israeli GeneRIF Biological Term Annotations 1.0 null cnv GeneRIF Biological Term Annotations 1.0 null LDAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73481 ASPC1 DepMap CRISPR Gene Dependency 1.0 2.22336 Prostate adenocarcinoma_PRAD_TCGA-G9-6384-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UJHI-1226-SM-4IHLR GTEx Tissue Sample Gene Expression Profiles 1.0 0.97461 H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A4TI-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRK-0326-SM-3NB3R GTEx Tissue Sample Gene Expression Profiles 1.0 1.06709 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDYL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05073 Apolipoprotein A-I dbGAP Gene-Trait Associations 1.0 0.061034 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null DPYSL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33538 ELAVL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97737 K029AX CCLE Cell Line Gene CNV Profiles -1.0 -1.36352 Hfl TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.64 locus GeneRIF Biological Term Annotations 1.0 null GTEX-POMQ-1426-SM-3P61D GTEx Tissue Sample Gene Expression Profiles 1.0 1.30947 PRRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.246 hsa-miR-3138 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 female GeneRIF Biological Term Annotations 1.0 null reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1056 compared GeneRIF Biological Term Annotations 1.0 null polymorphysms GeneRIF Biological Term Annotations 1.0 null lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.834847 htra1 GeneRIF Biological Term Annotations 1.0 null GTEX-XPVG-2126-SM-4B667 GTEx Tissue Sample Gene Expression Profiles 1.0 0.978618 hematopoietic system disease GWASdb SNP-Disease Associations 1.0 0.126067 basolateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2542 GTEX-PLZ6-1626-SM-3NB23 GTEx Tissue Sample Gene Expression Profiles 1.0 0.844736 ER membrane insertion complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.39 Rectum adenocarcinoma_READ_TCGA-EI-6512-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Peripheral nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.083 GTEX-UPIC-0326-SM-4IHJ9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06192 NCIH1963 CCLE Cell Line Gene CNV Profiles -1.0 -1.61153 number GeneRIF Biological Term Annotations 1.0 null highest GeneRIF Biological Term Annotations 1.0 null agedependent GeneRIF Biological Term Annotations 1.0 null GSE193541_1_v_3_nifurtimox_human RummaGEO Drug Perturbation Signatures -1.0 null PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null a69s GeneRIF Biological Term Annotations 1.0 null Serous Retinal Detachment DisGeNET Gene-Disease Associations 1.0 null abnormal eye morphology GWASdb SNP-Phenotype Associations 1.0 1.94642 P68-20966046-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Macular holes DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.387 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.57 common GeneRIF Biological Term Annotations 1.0 null hsa-miR-3126-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 about GeneRIF Biological Term Annotations 1.0 null cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.95488 ARHGAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37029 populations GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.42231 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49151 musculoskeletal system disease GWASdb SNP-Disease Associations 1.0 0.082536 Usher syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.082 cyss GeneRIF Biological Term Annotations 1.0 null splice GeneRIF Biological Term Annotations 1.0 null evidence GeneRIF Biological Term Annotations 1.0 null CPD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6794 PHF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96607 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.38733 genetically GeneRIF Biological Term Annotations 1.0 null supplementation GeneRIF Biological Term Annotations 1.0 null GSE178267_2_v_4_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null Parkinson's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.081 GTEX-RTLS-2326-SM-46MUH GTEx Tissue Sample Gene Expression Profiles 1.0 0.876198 choroidal neovascularization GAD Gene-Disease Associations 1.0 null ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.6166 GTEX-Q2AH-1726-SM-3NB2B GTEx Tissue Sample Gene Expression Profiles 1.0 1.43777 hip GAD Gene-Disease Associations 1.0 null GTEX-QDVN-2026-SM-3GAEP GTEx Tissue Sample Gene Expression Profiles 1.0 0.919069 Lung adenocarcinoma_LUAD_TCGA-86-8278-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HAP-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.615 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2198 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.863877 Lung adenocarcinoma_LUAD_TCGA-49-6744-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal genetic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 ratios GeneRIF Biological Term Annotations 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null genotyping GeneRIF Biological Term Annotations 1.0 null Intestinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.85 Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disorders GeneRIF Biological Term Annotations 1.0 null Age-related macular degeneration (GA) GWAS Catalog SNP-Phenotype Associations 1.0 1.49998 GSE145639_7_v_4_adar_human RummaGEO Gene Perturbation Signatures 1.0 null caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.880162 DKMG CCLE Cell Line Gene CNV Profiles -1.0 -1.80057 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null combined GeneRIF Biological Term Annotations 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.304381 R3HCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27833 BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6488 HCC1937 CCLE Cell Line Gene CNV Profiles 1.0 1.6048 loci GeneRIF Biological Term Annotations 1.0 null cfhdo GeneRIF Biological Term Annotations 1.0 null GTEX-X4XX-0011-R5A-SM-46MWN GTEx Tissue Sample Gene Expression Profiles 1.0 0.909436 496100576_HIP_dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.28565 basal nucleus of meynert, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05755 affects GeneRIF Biological Term Annotations 1.0 null coronary GeneRIF Biological Term Annotations 1.0 null NKX3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58826 Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macular degeneration GAD Gene-Disease Associations 1.0 null CDS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40205 SCLC21H CCLE Cell Line Gene CNV Profiles -1.0 -1.33382 genegene GeneRIF Biological Term Annotations 1.0 null photoreceptor inner segment GO Cellular Component Annotations 2015 1.0 null PTER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77138 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H157 DepMap CRISPR Gene Dependency 1.0 3.00154 HIVEP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62972 involvements GeneRIF Biological Term Annotations 1.0 null abnormality of lymphocytes GWASdb SNP-Phenotype Associations 1.0 0.841148 most GeneRIF Biological Term Annotations 1.0 null hematologic cancer GWASdb SNP-Disease Associations 1.0 0.23219 Basal laminar drusen DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.523 Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.339 TCIRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60988 likely GeneRIF Biological Term Annotations 1.0 null Neovascular inflammatory vitreoretinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.488 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.2309 SALL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55568 along GeneRIF Biological Term Annotations 1.0 null GTEX-Q2AG-2926-SM-2HMJ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02557 MDAMB361 DepMap CRISPR Gene Dependency 1.0 2.12967 hemorrhagic GeneRIF Biological Term Annotations 1.0 null macular degeneration GWASdb SNP-Disease Associations 1.0 4.56214 ZNF488 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80461 KNS81 CCLE Cell Line Gene CNV Profiles -1.0 -1.52941 MRPL24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92579 OSC19 DepMap CRISPR Gene Dependency 1.0 2.65937 HLA-A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22705 mechanisms GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NK-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null poor GeneRIF Biological Term Annotations 1.0 null geneenvironment GeneRIF Biological Term Annotations 1.0 null retinal degeneration GWASdb SNP-Disease Associations 1.0 2.86126 frh3 GeneRIF Biological Term Annotations 1.0 null NCIH524 CCLE Cell Line Gene CNV Profiles -1.0 -1.94654 Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHK1_KD_GSE54268_665_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-XQ3S-1426-SM-4BOPR GTEx Tissue Sample Gene Expression Profiles 1.0 1.13032 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null terms GeneRIF Biological Term Annotations 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.843872 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 2.35915 Acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.62 Retinal degeneration DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 CRYGD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59063 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.65092 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1783 geographic GeneRIF Biological Term Annotations 1.0 null 496100467_FWM_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.25567 ECC2 DepMap CRISPR Gene Dependency 1.0 2.06088 GSE118077_1_v_8_sprr5_human RummaGEO Gene Perturbation Signatures -1.0 null BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.862782 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40083 il8 GeneRIF Biological Term Annotations 1.0 null does GeneRIF Biological Term Annotations 1.0 null Vitreous detachment DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.617 ovary HPA Tissue Gene Expression Profiles 1.0 0.828436 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.67455 SERTAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28462 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69203 GTEX-T5JW-1226-SM-3GACY GTEx Tissue Sample Gene Expression Profiles 1.0 0.838022 primarily GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP Rummagene Transcription Factor Associations 2026 1.0 null extent GeneRIF Biological Term Annotations 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null angiographic GeneRIF Biological Term Annotations 1.0 null modify GeneRIF Biological Term Annotations 1.0 null increase GeneRIF Biological Term Annotations 1.0 null GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.42499 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.901999 DMRT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83248 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.83959 inferior colliculus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14513 snps GeneRIF Biological Term Annotations 1.0 null BT20 CCLE Cell Line Gene CNV Profiles -1.0 -2.45303 IRX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32525 Eye disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 visual GeneRIF Biological Term Annotations 1.0 null retinopathy GeneRIF Biological Term Annotations 1.0 null CENPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87922 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6407 longterm GeneRIF Biological Term Annotations 1.0 null AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21362 Overnutrition DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.635 Retinal microvascular endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.631 JRKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.3922 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.983 replicate GeneRIF Biological Term Annotations 1.0 null partially GeneRIF Biological Term Annotations 1.0 null GTEX-S4P3-1526-SM-3K2AV GTEx Tissue Sample Gene Expression Profiles 1.0 1.22568 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21804 pigments GeneRIF Biological Term Annotations 1.0 null GTEX-R53T-1626-SM-3GAEW GTEx Tissue Sample Gene Expression Profiles 1.0 0.959875 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08227 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.74956 SREBF2 JASPAR Predicted Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Thyroid gland disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.168 biological GeneRIF Biological Term Annotations 1.0 null degeneration of macula and posterior pole GWASdb SNP-Disease Associations 1.0 4.56214 Y-79 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.684 RPS24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02775 inner CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24417 arm GeneRIF Biological Term Annotations 1.0 null periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08452 Adrenocortical carcinoma_ACC_TCGA-OR-A5LR-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903627 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWN1-0726-SM-48TDR GTEx Tissue Sample Gene Expression Profiles 1.0 0.942749 Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null Polypoidal Choroidal Vasculopathy DisGeNET Gene-Disease Associations 1.0 null GTEX-RVPV-0011-R3A-SM-2TF63 GTEx Tissue Sample Gene Expression Profiles 1.0 0.882825 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.70156 hsa-miR-569 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8904 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.89783 GSE157635_1_v_0_trem2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RWS6-1026-SM-47JXD GTEx Tissue Sample Gene Expression Profiles 1.0 1.02998 Nervous system disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 SOX15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46864 SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1862 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null late-onset retinal degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.757 RBCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01482 GTEX-XUW1-0526-SM-4BOP3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.81755 CEP290 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96754 Retinal Pigment Epithelium Atrophy DisGeNET Gene-Disease Associations 1.0 null upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.885436 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasmic part GO Cellular Component Annotations 2015 1.0 null CX-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.636 metaanalysis GeneRIF Biological Term Annotations 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null obstructive lung disease GWASdb SNP-Disease Associations 1.0 0.4097 Age-related macular degeneration (extreme sampling) GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.85229 Exudative Macular Degeneration DisGeNET Gene-Disease Associations 1.0 null poorer GeneRIF Biological Term Annotations 1.0 null cfh GeneRIF Biological Term Annotations 1.0 null onset GeneRIF Biological Term Annotations 1.0 null analyses GeneRIF Biological Term Annotations 1.0 null Degeneration of macula and posterior pole DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 Lateral geniculate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.674 Age related macular degeneration DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.852195 Bipolar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.681 background GeneRIF Biological Term Annotations 1.0 null choroid diseases; choroidal neovascularization; macular degeneration; peripheral vascular diseases GAD Gene-Disease Associations 1.0 null eyes GeneRIF Biological Term Annotations 1.0 null Retinal macular dystrophy 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.265 chromosome GeneRIF Biological Term Annotations 1.0 null KARPAS299 CCLE Cell Line Gene CNV Profiles -1.0 -1.52365 Retinal pigment epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 3.128 ACSL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56063 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.872442 Age related macular degeneration 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.052 Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.9749 combination GeneRIF Biological Term Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Monogenic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 loc387715 GeneRIF Biological Term Annotations 1.0 null 496100334_PCx_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.14772 RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.736 GTEX-TML8-1926-SM-32QOS GTEx Tissue Sample Gene Expression Profiles 1.0 0.885655 Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spine apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.872 atrisk GeneRIF Biological Term Annotations 1.0 null deficiency GeneRIF Biological Term Annotations 1.0 null GTEX-PX3G-0226-SM-3NB2C GTEx Tissue Sample Gene Expression Profiles 1.0 1.16851 FOXD4L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.30813 GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 0.927896 SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21804 OVK18 CCLE Cell Line Gene CNV Profiles 1.0 1.45578 LRPPRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98526 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.889396 Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TG-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A705-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF282 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.9084 TERB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19408 PAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35661 Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null had GeneRIF Biological Term Annotations 1.0 null phenotype GeneRIF Biological Term Annotations 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48784 NR1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78131 americans GeneRIF Biological Term Annotations 1.0 null GTEX-XMD3-2326-SM-4AT5H GTEx Tissue Sample Gene Expression Profiles 1.0 1.27624 Soft Drusen DisGeNET Gene-Disease Associations 1.0 null populationbased GeneRIF Biological Term Annotations 1.0 null black GeneRIF Biological Term Annotations 1.0 null process GeneRIF Biological Term Annotations 1.0 null RELB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61542 genotypic GeneRIF Biological Term Annotations 1.0 null L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49443 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 1.45947 ZNF708 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64904 ZBED4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86544 CD47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32753 vasculopathy GeneRIF Biological Term Annotations 1.0 null Bardet-Biedl syndrome 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.091 TACSTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77875 GTEX-XAJ8-0926-SM-47JXZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.17445 Glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.755 least GeneRIF Biological Term Annotations 1.0 null U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69203 MT-ND4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12654 contribute GeneRIF Biological Term Annotations 1.0 null PHC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94116 GTEX-X4EO-2926-SM-4E3JH GTEx Tissue Sample Gene Expression Profiles 1.0 0.888957 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.15792 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28227 contributing GeneRIF Biological Term Annotations 1.0 null Complement component C1q complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.436 Atherosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.547 NDUFB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97147 BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5525 pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54533 Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51904 hsa-miR-1587 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.173 HUG1N CCLE Cell Line Gene CNV Profiles 1.0 1.58276 APOE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82522 tests GeneRIF Biological Term Annotations 1.0 null NCIH1435 CCLE Cell Line Gene CNV Profiles 1.0 1.81258 stages GeneRIF Biological Term Annotations 1.0 null predicted GeneRIF Biological Term Annotations 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852436 PMM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31839 GTEX-U4B1-1726-SM-3DB9F GTEx Tissue Sample Gene Expression Profiles 1.0 0.931231 Pigment granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.693 second GeneRIF Biological Term Annotations 1.0 null assessed GeneRIF Biological Term Annotations 1.0 null rs10490924 GeneRIF Biological Term Annotations 1.0 null Retinal detachment DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.344 genotypes GeneRIF Biological Term Annotations 1.0 null all GeneRIF Biological Term Annotations 1.0 null homozygotes GeneRIF Biological Term Annotations 1.0 null GTEX-RU72-0326-SM-2TF5T GTEx Tissue Sample Gene Expression Profiles 1.0 0.922829 VPS4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39018 Collagen type IV trimer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.519 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9573 evaluation GeneRIF Biological Term Annotations 1.0 null intracellular organelle GO Cellular Component Annotations 2015 1.0 null Sarcoma_SARC_TCGA-PC-A5DK-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pseudoxanthoma elasticum DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.711 GTEX-S32W-1226-SM-4AD67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36643 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null ZNF843 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1833 Macular degeneration ClinVar Gene-Phenotype Associations 2025 1.0 null forms GeneRIF Biological Term Annotations 1.0 null ZNF862 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.118 Disease progression to choroidal neovascularization form in age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.5 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01689 Mueller cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.946 Sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.88 correlated GeneRIF Biological Term Annotations 1.0 null reported GeneRIF Biological Term Annotations 1.0 null dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27481 alzheimer's disease GAD Gene-Disease Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6436-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Obesity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.637 Chronic Central Serous Chorioretinopathy DisGeNET Gene-Disease Associations 1.0 null GSE216043_10_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null ocular GeneRIF Biological Term Annotations 1.0 null CSDE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95695 GTEX-Q2AG-0226-SM-2S1P4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.913955 GTEX-QDT8-0426-SM-32PKZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.970931 ZNF502 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71715 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BT474 CCLE Cell Line Gene CNV Profiles -1.0 -2.70802 SGTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65792 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35869 replication GeneRIF Biological Term Annotations 1.0 null Ciliary epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.545 H2AC19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47255 PPIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25457 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r38x GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DY-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-WK-A8XX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51J-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arl6 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.642 Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TTI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3255 Eye disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 UBE2L6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68787 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6915 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Age-related macular degeneration (geographic atrophy) GWAS Catalog SNP-Phenotype Associations 2025 1.0 4.61549 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64348 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4776-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40446 ascertainment GeneRIF Biological Term Annotations 1.0 null BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.30183 PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF Rummagene Transcription Factor Associations 2026 1.0 null GTF2A1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25113 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.6322 Basal Laminar Drusen (Disorder) DisGeNET Gene-Disease Associations 1.0 null exon GeneRIF Biological Term Annotations 1.0 null SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.30309 MAN2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45807 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3YQ-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null epithelial GeneRIF Biological Term Annotations 1.0 null GTEX-V955-1026-SM-4JBHO GTEx Tissue Sample Gene Expression Profiles 1.0 1.12607 GBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53496 times GeneRIF Biological Term Annotations 1.0 null GTEX-XUW1-0126-SM-4BOOQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.896891 Complement deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.662 involvement GeneRIF Biological Term Annotations 1.0 null GTEX-XUJ4-1326-SM-4BOQ9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09383 Leber congenital amaurosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.572 Achromatopsia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.023 replacement GeneRIF Biological Term Annotations 1.0 null arms2htra GeneRIF Biological Term Annotations 1.0 null Uveitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.65 biomarker GeneRIF Biological Term Annotations 1.0 null Vitreous humor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.801 HK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81977 Scolopidium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.68 korea GeneRIF Biological Term Annotations 1.0 null GTEX-P78B-2226-SM-3P5ZZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.925496 SLCO4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9602 Disease progression in age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 2025 1.0 4.20969 photodynamic GeneRIF Biological Term Annotations 1.0 null GTEX-P4PP-2026-SM-3P61N GTEx Tissue Sample Gene Expression Profiles 1.0 0.954137 KMCH1 DepMap CRISPR Gene Dependency 1.0 4.63291 EMC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59131 ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.7625 MARK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04578 MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5733 TFRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24084 GTEX-W5WG-2726-SM-4LMIC GTEx Tissue Sample Gene Expression Profiles 1.0 1.13252 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autoimmune disease of musculoskeletal system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.205 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47W-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.869687 their GeneRIF Biological Term Annotations 1.0 null GTEX-SNMC-0226-SM-4DM6F GTEx Tissue Sample Gene Expression Profiles 1.0 0.871885 H2AFZ ENCODE Transcription Factor Targets 1.0 null GTEX-X8HC-1526-SM-46MWD GTEx Tissue Sample Gene Expression Profiles 1.0 1.13834 abnormality of the fundus GWASdb SNP-Phenotype Associations 1.0 2.37396 Cataract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.391 blood GTEx Tissue Gene Expression Profiles -1.0 -2.09703 absence GeneRIF Biological Term Annotations 1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.69798 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20797 PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY Rummagene Transcription Factor Associations 2026 1.0 null highsensitivity GeneRIF Biological Term Annotations 1.0 null will GeneRIF Biological Term Annotations 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null northern GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5498-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Chamber of the eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.716 K029AX DepMap CRISPR Gene Dependency 1.0 2.26427 subphenotype GeneRIF Biological Term Annotations 1.0 null NEUROD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4496 supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.970949 GTEX-QEG5-0626-SM-2S1PP GTEx Tissue Sample Gene Expression Profiles 1.0 0.949743 antioxidantonly GeneRIF Biological Term Annotations 1.0 null Age-related macular degeneration (choroidal neovascularisation) GWAS Catalog SNP-Phenotype Associations 2025 1.0 10.0 CCDC61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90336 agerelated GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A4T4-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased GeneRIF Biological Term Annotations 1.0 null affect GeneRIF Biological Term Annotations 1.0 null CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null maculopathy GeneRIF Biological Term Annotations 1.0 null Retinal degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.516 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16258 GTEX-T5JC-0226-SM-32PMA GTEx Tissue Sample Gene Expression Profiles 1.0 0.895405 YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.80816 Vascular Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null Rod photoreceptor outer segment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.26 DEDD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67255 retinas GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8191-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null Diabetic macular edema DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.604 Mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.066 MAP3K9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62736 maximum GeneRIF Biological Term Annotations 1.0 null PKN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83714 RCOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78645 SPACA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.758 age-related macular degeneration GWASdb SNP-Phenotype Associations 1.0 4.73758 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09302 MAP4K5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3428 GREB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80087 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 analyzed GeneRIF Biological Term Annotations 1.0 null hTERT-RPE1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.678 geographic atrophy; macular degeneration; retinal drusen GAD Gene-Disease Associations 1.0 null HCA1 DepMap CRISPR Gene Dependency 1.0 2.90272 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE217873_1_v_0_nusap1_human RummaGEO Gene Perturbation Signatures -1.0 null early GeneRIF Biological Term Annotations 1.0 null Artery disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.908 TMEM89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94709 validation GeneRIF Biological Term Annotations 1.0 null Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.038 developing GeneRIF Biological Term Annotations 1.0 null neuron part GO Cellular Component Annotations 2015 1.0 null Bullous retinoschisis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.099 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903627 ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.895239 smoking GeneRIF Biological Term Annotations 1.0 null hsa-miR-4434 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 MINPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15663 fh57 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.993 JTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84568 Atypical hemolytic-uremic syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.67 GTEX-XPVG-0926-SM-4B651 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03162 Macular degeneration DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 Age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.9699 Lung adenocarcinoma_LUAD_TCGA-86-A4P7-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-23b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 marker GeneRIF Biological Term Annotations 1.0 null ARPE cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.927 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 2.14701 organ system cancer GWASdb SNP-Disease Associations 1.0 0.080001 Lung adenocarcinoma_LUAD_TCGA-55-6969-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null several GeneRIF Biological Term Annotations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retinal Pigment Epithelial Detachment DisGeNET Gene-Disease Associations 1.0 null RNF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15428 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Chorioretinal scar DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.36 FGD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96266 diabetes mellitus, type 2; inflammatory bowel diseases; macular degeneration; prostatic neoplasms GAD Gene-Disease Associations 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 WM115 CCLE Cell Line Gene CNV Profiles -1.0 -1.54098 ZNF410 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8303 Outer plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.975 Retinal vascular occlusion DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.859 Amacrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.375 ethnically GeneRIF Biological Term Annotations 1.0 null Membranoproliferative glomerulonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.729 Night blindness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.515 X-linked juvenile retinoschisis 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.467 Autoimmune disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.158 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26842 Mesothelioma_MESO_TCGA-MQ-A6BQ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hypertensive retinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.21 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.88043 OPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37821 associations GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KC-A4BL-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null confirmed GeneRIF Biological Term Annotations 1.0 null elderly GeneRIF Biological Term Annotations 1.0 null further GeneRIF Biological Term Annotations 1.0 null GTEX-XPVG-1426-SM-4B668 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05847 YAMATO DepMap CRISPR Gene Dependency 1.0 2.58666 NCIH1993 DepMap CRISPR Gene Dependency 1.0 2.16529 MOLP8 CCLE Cell Line Gene CNV Profiles -1.0 -1.82902 clinicbased GeneRIF Biological Term Annotations 1.0 null elevation GeneRIF Biological Term Annotations 1.0 null Keratoconus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.291 Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.158 old GeneRIF Biological Term Annotations 1.0 null bone resorption disease GWASdb SNP-Disease Associations 1.0 0.892579 MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3869 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.70852 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881828 mestizos GeneRIF Biological Term Annotations 1.0 null Corneal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.361 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null consistently GeneRIF Biological Term Annotations 1.0 null GTEX-PWN1-0226-SM-2S1OZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.48504 hsa-miR-4779 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Brahma complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.96 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.224 SNU520 CCLE Cell Line Gene CNV Profiles 1.0 1.35914 did GeneRIF Biological Term Annotations 1.0 null RAD54B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39053 choroid diseases; peripheral vascular diseases; vitreous hemorrhage GAD Gene-Disease Associations 1.0 null GTEX-RVPU-1526-SM-47JXQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.834803 Retinitis Pigmentosa HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-S4P3-0926-SM-4AD54 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14199 Eye degenerative disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.885892 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 3.05005 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CK-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.30732 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.966804 SNU398 CCLE Cell Line Gene CNV Profiles 1.0 1.40633 U178 CCLE Cell Line Gene CNV Profiles -1.0 -1.39111 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.84415 affecting GeneRIF Biological Term Annotations 1.0 null GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.995784 TRC complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.521 CARASIL syndrome ClinVar Gene-Phenotype Associations 2025 1.0 null degenerationassociated GeneRIF Biological Term Annotations 1.0 null HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6399 exerted GeneRIF Biological Term Annotations 1.0 null outer CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17779 atrophy GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100447_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02248 loc387715arms2htra1 GeneRIF Biological Term Annotations 1.0 null FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 102.042 GTEX-UPIC-0226-SM-3GADO GTEx Tissue Sample Gene Expression Profiles 1.0 1.0371 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54296 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-W5WG-2226-SM-4LMI3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05868 tentative GeneRIF Biological Term Annotations 1.0 null Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.75 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53385 NAIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3737 Rh-18 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.648 inner CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35847 hsa-miR-3925-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Migraine GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 Retinal vein occlusion DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.798 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.81021 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.94509 degeneration GeneRIF Biological Term Annotations 1.0 null H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.79154 GTEX-X8HC-2726-SM-46MUA GTEx Tissue Sample Gene Expression Profiles 1.0 1.40763 ACER2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3475 frequent GeneRIF Biological Term Annotations 1.0 null Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.364 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903627 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28869 GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2998 DepMap CRISPR Gene Dependency 1.0 5.7467 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.944388 considering GeneRIF Biological Term Annotations 1.0 null Brain disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.202 review GeneRIF Biological Term Annotations 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.856942 9+0 non-motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.292 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.10788 chr10_122380394_T_C_b38 GTEx eQTL 2025 1.0 1.61866 retina homeostasis GO Biological Process Annotations 2015 1.0 null ancestral GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTP4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26814 hypothetical GeneRIF Biological Term Annotations 1.0 null supplements GeneRIF Biological Term Annotations 1.0 null controls GeneRIF Biological Term Annotations 1.0 null GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.76021 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67075 Lung adenocarcinoma_LUAD_TCGA-55-6986-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hyalocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.66 Retinal ganglion cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.759 totally GeneRIF Biological Term Annotations 1.0 null chr10_122459759_C_G_b38 GTEx eQTL 2025 1.0 4.41198 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.19902 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1681 rs1410996 GeneRIF Biological Term Annotations 1.0 null Degenerative myopia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.824 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33546 Exudative Age-Related Macular Degeneration DisGeNET Gene-Disease Associations 1.0 null composition GeneRIF Biological Term Annotations 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3251 atrophychoroidal GeneRIF Biological Term Annotations 1.0 null Ski complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.257 regulation of biological quality GO Biological Process Annotations 2015 1.0 null nutritional GeneRIF Biological Term Annotations 1.0 null H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21362 GSE193258,GSE193259_2_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 66.783 GTEX-X3Y1-0926-SM-3P5YT GTEx Tissue Sample Gene Expression Profiles 1.0 0.890083 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.954122 favorable GeneRIF Biological Term Annotations 1.0 null Tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.538 Age related macular degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.696 true GeneRIF Biological Term Annotations 1.0 null SG231 DepMap CRISPR Gene Dependency 1.0 6.11022 Paroxysmal nocturnal hemoglobinuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.183 LY6E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92796 MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0659 carry GeneRIF Biological Term Annotations 1.0 null TMED5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26743 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.564 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.68937 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A44S-01A-12R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.58637 choroid diseases; macular degeneration; peripheral vascular diseases; retinal neovascularization GAD Gene-Disease Associations 1.0 null casecontrol GeneRIF Biological Term Annotations 1.0 null groups GeneRIF Biological Term Annotations 1.0 null lesion GeneRIF Biological Term Annotations 1.0 null COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11662 Lung adenocarcinoma_LUAD_TCGA-L4-A4E6-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCYOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.37162 REX1BD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22738 interacts GeneRIF Biological Term Annotations 1.0 null Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38483 HCC827GR5 DepMap CRISPR Gene Dependency 1.0 2.26592 incorrect GeneRIF Biological Term Annotations 1.0 null SNU1272 CCLE Cell Line Gene CNV Profiles 1.0 1.73328 GTEX-WRHU-2826-SM-3MJG8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.868913 Kidney failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.019 GOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18984 eye and adnexa disease GWASdb SNP-Disease Associations 1.0 1.99945 packyears GeneRIF Biological Term Annotations 1.0 null NADSYN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70836 putatively GeneRIF Biological Term Annotations 1.0 null Primary open angle glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.588 Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NJ-01A-22R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74771 independently GeneRIF Biological Term Annotations 1.0 null Fundus dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.115 496100571_FWM_dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.38059 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A69L-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phenotypic GeneRIF Biological Term Annotations 1.0 null RBFOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79902 Arteriosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.624 immune system disease GWASdb SNP-Disease Associations 1.0 0.062536 Nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 appear GeneRIF Biological Term Annotations 1.0 null eye GeneRIF Biological Term Annotations 1.0 null inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42849 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null presumptive GeneRIF Biological Term Annotations 1.0 null 496100465_HIP_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.249 Capillary endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.826 Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null GBF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55051 RLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55566 first GeneRIF Biological Term Annotations 1.0 null drusen GeneRIF Biological Term Annotations 1.0 null NCIH1694 CCLE Cell Line Gene CNV Profiles -1.0 -2.12313 choroiditis; macular degeneration GAD Gene-Disease Associations 1.0 null GTEX-S32W-2126-SM-2XCB1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.862104 hsa-miR-590-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GTEX-TSE9-2226-SM-4DXUR GTEx Tissue Sample Gene Expression Profiles 1.0 1.40374 Cone photoreceptor outer segment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.681 wet GeneRIF Biological Term Annotations 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32267 single GeneRIF Biological Term Annotations 1.0 null fovea GeneRIF Biological Term Annotations 1.0 null clinically GeneRIF Biological Term Annotations 1.0 null statistically GeneRIF Biological Term Annotations 1.0 null haplotype GeneRIF Biological Term Annotations 1.0 null represents GeneRIF Biological Term Annotations 1.0 null GSE118077_7_v_2_sprr5_human RummaGEO Gene Perturbation Signatures 1.0 null abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.1039 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null QSOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.39351 Eyelid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.203 GTEX-NPJ8-0011-R7a-SM-2HMJV GTEx Tissue Sample Gene Expression Profiles 1.0 1.10888 amdrisk GeneRIF Biological Term Annotations 1.0 null SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.95912 ZNF519 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75528 placenta HPA Tissue Gene Expression Profiles 1.0 1.99519 CBR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55192 TCF7L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05123 accelerated GeneRIF Biological Term Annotations 1.0 null THG1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.6565 RUSC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30426 CREB1 JASPAR Predicted Transcription Factor Targets 1.0 null brazilian GeneRIF Biological Term Annotations 1.0 null effect GeneRIF Biological Term Annotations 1.0 null Sarcoma_SARC_TCGA-IS-A3K7-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Synucleinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.077 Geographic Atrophy DisGeNET Gene-Disease Associations 1.0 null Impaired Cognition DisGeNET Gene-Disease Associations 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.534 odds GeneRIF Biological Term Annotations 1.0 null Vision Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null Retinal drusen DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.651 RUNX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7635 abnormality of the retina GWASdb SNP-Phenotype Associations 1.0 2.50139 retinal diseases GAD Gene-Disease Associations 1.0 null Sarcoma_SARC_TCGA-SI-A71O-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFKBIE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50366 SIX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48475 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GR-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.951183 Migraine DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.063 PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63 Rummagene Transcription Factor Associations 2026 1.0 null Atherosclerosis HuGE Navigator Gene-Phenotype Associations 1.0 null inserting GeneRIF Biological Term Annotations 1.0 null GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.98268 PEX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60337 molecular GeneRIF Biological Term Annotations 1.0 null minor GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A4XH-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macular GeneRIF Biological Term Annotations 1.0 null GTEX-QV31-1626-SM-2S1QC GTEx Tissue Sample Gene Expression Profiles 1.0 0.960319 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.17472 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cyp46a1 GeneRIF Biological Term Annotations 1.0 null amrs2 GeneRIF Biological Term Annotations 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.984235 Retinal edema DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.012 Hypertension HuGE Navigator Gene-Phenotype Associations 1.0 null control GeneRIF Biological Term Annotations 1.0 null concentrations GeneRIF Biological Term Annotations 1.0 null region GeneRIF Biological Term Annotations 1.0 null Hyperopia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.341 present GeneRIF Biological Term Annotations 1.0 null small GeneRIF Biological Term Annotations 1.0 null without GeneRIF Biological Term Annotations 1.0 null GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.72406 one GeneRIF Biological Term Annotations 1.0 null reports GeneRIF Biological Term Annotations 1.0 null VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.58772 il6 GeneRIF Biological Term Annotations 1.0 null Macular degeneration DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.07 THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 DHX36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56982 PTP4A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81906 lrp5 GeneRIF Biological Term Annotations 1.0 null GTEX-T6MO-1026-SM-4DM72 GTEx Tissue Sample Gene Expression Profiles 1.0 0.994679 GTEX-N7MT-0726-SM-3TW8S GTEx Tissue Sample Gene Expression Profiles 1.0 1.17567 PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR Rummagene Transcription Factor Associations 2026 1.0 null JADE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70116 investigated GeneRIF Biological Term Annotations 1.0 null abnormality of the eye GWASdb SNP-Phenotype Associations 1.0 1.65453 Retinal Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TLX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4253 POLR2A ENCODE Transcription Factor Targets 1.0 null distributed GeneRIF Biological Term Annotations 1.0 null CDK11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72158 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GCFC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86714 CNIH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9102 ZNF426 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45931 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.58489 tyr402his GeneRIF Biological Term Annotations 1.0 null RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09787 Lung adenocarcinoma_LUAD_TCGA-55-6979-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCTS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49044 Exfoliation syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.487 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.96614 allelesgenotypes GeneRIF Biological Term Annotations 1.0 null choroidal neovascularization; macular degeneration GAD Gene-Disease Associations 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.46774 Uveal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.812 Blindness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.096 relationship GeneRIF Biological Term Annotations 1.0 null PROP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44557 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881828 ZNF831 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65867 TKFC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45916 Flagellum attachment zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.571 macular degeneration; peripheral vascular diseases GAD Gene-Disease Associations 1.0 null Kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.331 similar GeneRIF Biological Term Annotations 1.0 null cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.94871 Macular retinal edema DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.913 Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ES5 DepMap CRISPR Gene Dependency 1.0 2.73382 SPIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33099 benefit GeneRIF Biological Term Annotations 1.0 null leukopenia GWASdb SNP-Disease Associations 1.0 0.4097 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1215 ZNF81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19508 understanding GeneRIF Biological Term Annotations 1.0 null myopic GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210682_2_v_3_methadone_human RummaGEO Drug Perturbation Signatures -1.0 null areds GeneRIF Biological Term Annotations 1.0 null LRRC4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19367 pcv GeneRIF Biological Term Annotations 1.0 null Kuhnt-Junius degeneration DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 2.062 Familial partial lipodystrophy type 5 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.176 even GeneRIF Biological Term Annotations 1.0 null cases GeneRIF Biological Term Annotations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Retinal disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 TRMT112 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10901 CYYR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18977 Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.837364 RAB3GAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58578 Degeneration of macula and posterior pole DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48992 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78271 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.9054 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null distributions GeneRIF Biological Term Annotations 1.0 null BACH1 ENCODE Transcription Factor Targets 1.0 null Autoimmune disease of endocrine system DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.158 H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CW9019 DepMap CRISPR Gene Dependency 1.0 3.09041 bone remodeling disease GWASdb SNP-Disease Associations 1.0 0.401319 Pore complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.901 Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVSAHO CCLE Cell Line Gene CNV Profiles 1.0 2.36918 Mesopic Vision HuGE Navigator Gene-Phenotype Associations 1.0 null hsa-miR-4516 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.92977 BTF3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20399 ratio GeneRIF Biological Term Annotations 1.0 null lesser GeneRIF Biological Term Annotations 1.0 null clinical GeneRIF Biological Term Annotations 1.0 null Hemoglobinuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.136 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09721 Acute Myeloid Leukemia_LAML_TCGA-AB-3000-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null imparts GeneRIF Biological Term Annotations 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-6655-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null positive GeneRIF Biological Term Annotations 1.0 null ZDHHC20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94004 Macular Degeneration HuGE Navigator Gene-Phenotype Associations 1.0 null Sarcoma_SARC_TCGA-SI-AA8B-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rs10490924htra1 GeneRIF Biological Term Annotations 1.0 null Tear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.776 Retinal Drusen DisGeNET Gene-Disease Associations 1.0 null lesions GeneRIF Biological Term Annotations 1.0 null abnormality of leukocytes GWASdb SNP-Phenotype Associations 1.0 0.119873 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0643 HMGA1_02_75 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.34577 OVMIU DepMap CRISPR Gene Dependency 1.0 5.22093 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6734 Photoreceptor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.858 Iris disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.451 non-motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.394 GTEX-T2IS-2026-SM-4DM6W GTEx Tissue Sample Gene Expression Profiles 1.0 1.98539 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal dominant disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 SDAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28705 atherosclerosis; myocardial infarction GAD Gene-Disease Associations 1.0 null DLST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75714 mediate GeneRIF Biological Term Annotations 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 2.32094 Diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.764 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.859686 lymphopenia GWASdb SNP-Disease Associations 1.0 0.95488 among GeneRIF Biological Term Annotations 1.0 null other GeneRIF Biological Term Annotations 1.0 null asthma GWASdb SNP-Disease Associations 1.0 0.95488 hsa-miR-940 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12076 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13631 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.53836 Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PK59 CCLE Cell Line Gene CNV Profiles -1.0 -1.4348 inflammatory GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6U6-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal genetic disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67952 Optic nerve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.315 rs800292 GeneRIF Biological Term Annotations 1.0 null Stargardt Disease 1 (Disorder) DisGeNET Gene-Disease Associations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BH-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.60861 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.58795 ZCCHC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00722 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03678 Buffy coat TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.231 abnormality of the hip bone GWASdb SNP-Phenotype Associations 1.0 0.784165 ARHGEF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19592 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4165 ENGASE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46454 therapy GeneRIF Biological Term Annotations 1.0 null GTEX-T8EM-1126-SM-3DB7D GTEx Tissue Sample Gene Expression Profiles 1.0 0.830668 Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.4908 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Macular degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.681 led GeneRIF Biological Term Annotations 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.954122 POFUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.994 turnover GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15635 CREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5358 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99578 GTEX-UPK5-0326-SM-3GAF3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17934 Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null consistent GeneRIF Biological Term Annotations 1.0 null H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZW-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ps92 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.828 carrying GeneRIF Biological Term Annotations 1.0 null Myopia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.314 C3A CCLE Cell Line Gene CNV Profiles 1.0 1.33232 connection GeneRIF Biological Term Annotations 1.0 null australia GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Diabetic Retinopathy HuGE Navigator Gene-Phenotype Associations 1.0 null caucasian GeneRIF Biological Term Annotations 1.0 null GSE114284_4_v_3_irf1_human RummaGEO Gene Perturbation Signatures 1.0 null caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12651 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null age-related macular degeneration GAD Gene-Disease Associations 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.86056 Retinal cone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.57 G3BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3421 abnormality of cellular immune system GWASdb SNP-Phenotype Associations 1.0 0.119873 TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.836 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.5613 Choroid disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.637 H3K4ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GALNT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8805 influence GeneRIF Biological Term Annotations 1.0 null Corneal Dystrophies, Hereditary HuGE Navigator Gene-Phenotype Associations 1.0 null atherosclerosis; hypertension; macular degeneration; prostatic neoplasms GAD Gene-Disease Associations 1.0 null substitution GeneRIF Biological Term Annotations 1.0 null MFSD14A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41678 CCNF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89472 GLB1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88995 SMC1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88292 balanced GeneRIF Biological Term Annotations 1.0 null only GeneRIF Biological Term Annotations 1.0 null heart disease GWASdb SNP-Disease Associations 1.0 0.892579 Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF382 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5223 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.865055 Prostatic Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XPVG-1326-SM-4B65P GTEx Tissue Sample Gene Expression Profiles 1.0 0.925594 SP in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.878382 markers GeneRIF Biological Term Annotations 1.0 null VEGF-A complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.461 Ciliary membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.83 green GeneRIF Biological Term Annotations 1.0 null estimation GeneRIF Biological Term Annotations 1.0 null 661W cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.005 SRSF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.21403 Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN45 CCLE Cell Line Gene CNV Profiles 1.0 2.39761 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.44711 mexican GeneRIF Biological Term Annotations 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53 Rummagene Transcription Factor Associations 2026 1.0 null relationships GeneRIF Biological Term Annotations 1.0 null highrisk GeneRIF Biological Term Annotations 1.0 null promoter GeneRIF Biological Term Annotations 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39406 SNU668 CCLE Cell Line Gene CNV Profiles 1.0 2.10365 health GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATRFLOX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72729 outer CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.860841 Ganglion cell layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.936 Doyne honeycomb retinal dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.067 Complement component C1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.947 Pancreatic adenocarcinoma_PAAD_TCGA-FB-A7DR-01A-21R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Optic cup TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.511 SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 alleles GeneRIF Biological Term Annotations 1.0 null abnormality of pelvic girdle bone morphology GWASdb SNP-Phenotype Associations 1.0 0.784165 Retinal macular dystrophy 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.073 Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cybrid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.646 ENTPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4305 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.37554 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03343 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.85424 investigate GeneRIF Biological Term Annotations 1.0 null GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.11572 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54869 unlikely GeneRIF Biological Term Annotations 1.0 null involving GeneRIF Biological Term Annotations 1.0 null Arteriosclerotic cardiovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.547 mitochondria GeneRIF Biological Term Annotations 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.90728 wellpowered GeneRIF Biological Term Annotations 1.0 null power GeneRIF Biological Term Annotations 1.0 null GSE181517_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.36112 confirmation GeneRIF Biological Term Annotations 1.0 null abnormal appendicular skeleton morphology GWASdb SNP-Phenotype Associations 1.0 0.214927 such GeneRIF Biological Term Annotations 1.0 null current GeneRIF Biological Term Annotations 1.0 null RPS20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51368 GTEX-OIZH-1526-SM-3NB1J GTEx Tissue Sample Gene Expression Profiles 1.0 0.909211 Choroidal sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.434 OVISE CCLE Cell Line Gene CNV Profiles 1.0 2.19519 amdassociated GeneRIF Biological Term Annotations 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null environmental GeneRIF Biological Term Annotations 1.0 null omega3 GeneRIF Biological Term Annotations 1.0 null genotype GeneRIF Biological Term Annotations 1.0 null Central Serous Chorioretinopathy DisGeNET Gene-Disease Associations 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12007 GTEX-QLQ7-1626-SM-2S1R8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08666 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.865104 Protein Deficiency DisGeNET Gene-Disease Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4680-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Bleb COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.093 determining GeneRIF Biological Term Annotations 1.0 null PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2924 CAL29 DepMap CRISPR Gene Dependency 1.0 4.64375 GTEX-P78B-1926-SM-3P616 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54823 SUPT1 DepMap CRISPR Gene Dependency 1.0 3.30288 according GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-1595-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-2626-SM-4DXV2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.851857 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949558 Unspecified Visual Loss DisGeNET Gene-Phenotype Associations 1.0 null 496100380_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.39512 Diseases in Twins HuGE Navigator Gene-Phenotype Associations 1.0 null OVCA420 DepMap CRISPR Gene Dependency 1.0 2.72898 homozygous GeneRIF Biological Term Annotations 1.0 null Cerebrovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.365 Refractive error DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.363 Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null having GeneRIF Biological Term Annotations 1.0 null icSARS CoV_3Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -0.4856 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null differences GeneRIF Biological Term Annotations 1.0 null ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2997 principal GeneRIF Biological Term Annotations 1.0 null Ribonuclease P complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.851 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cfb GeneRIF Biological Term Annotations 1.0 null Eye degenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.512 low GeneRIF Biological Term Annotations 1.0 null B4GALT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8542 VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54327 Wet Macular Degeneration HuGE Navigator Gene-Phenotype Associations 1.0 null Neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.153 retinal GeneRIF Biological Term Annotations 1.0 null TECPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20374 Retinoschisis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.526 strong GeneRIF Biological Term Annotations 1.0 null SKMEL30 DepMap CRISPR Gene Dependency 1.0 3.2574 CCNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15675 GTEX-OXRL-1826-SM-2YUMV GTEx Tissue Sample Gene Expression Profiles 1.0 0.901203 NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.932093 Neural retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.381 PYGB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84002 496100532_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.59792 nutrition disease GWASdb SNP-Disease Associations 1.0 0.401319 MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.55371 VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27794 SP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41998 ADIPOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44085 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.32481 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02874 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05875 korean GeneRIF Biological Term Annotations 1.0 null superior parietal lobule, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.868915 H3-4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73527 epithelium GeneRIF Biological Term Annotations 1.0 null Eye TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 known GeneRIF Biological Term Annotations 1.0 null GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.83078 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.872283 KMM1 CCLE Cell Line Gene CNV Profiles 1.0 1.34441 UMUC3 DepMap CRISPR Gene Dependency 1.0 3.44531 HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2443 hsa-miR-31 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null responses GeneRIF Biological Term Annotations 1.0 null Exudative age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 2025 1.0 10.0 subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.946094 Lens disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.388 Arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.206 ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.7607 HOXC13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0019 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06564 loc387715htra1 GeneRIF Biological Term Annotations 1.0 null more GeneRIF Biological Term Annotations 1.0 null zinconly GeneRIF Biological Term Annotations 1.0 null large GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLEKHH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15489 GSE214931_2_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null connective tissue disease GWASdb SNP-Disease Associations 1.0 0.115195 GJA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01297 Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neovascularization, Pathologic HuGE Navigator Gene-Phenotype Associations 1.0 null good GeneRIF Biological Term Annotations 1.0 null GTEX-X4EO-0326-SM-3P5YO GTEx Tissue Sample Gene Expression Profiles 1.0 0.891726 NCIH2882 DepMap CRISPR Gene Dependency 1.0 2.11932 Monogenic disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 vision GeneRIF Biological Term Annotations 1.0 null Ocular albinism 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.087 mainly GeneRIF Biological Term Annotations 1.0 null outer GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4436 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.110319 NCIH1436 CCLE Cell Line Gene CNV Profiles 1.0 1.33119 provided GeneRIF Biological Term Annotations 1.0 null fh14 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.569 GTEX-XQ3S-1226-SM-4BOPP GTEx Tissue Sample Gene Expression Profiles 1.0 1.00003 respiratory system disease GWASdb SNP-Disease Associations 1.0 0.23219 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01471 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null constituent GeneRIF Biological Term Annotations 1.0 null ARPE-19 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.96 after GeneRIF Biological Term Annotations 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKMM2 DepMap CRISPR Gene Dependency 1.0 9.54201 SETDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06791 GTEX-O5YW-3026-SM-3MJHI GTEx Tissue Sample Gene Expression Profiles 1.0 1.03551 CTAGE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61345 HES4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66291 NFAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82024 KHK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44642 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hemolytic-uremic syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.072 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16975 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.63192 RAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.598 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03197 Vitelliform macular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.948 Sarcoma_SARC_TCGA-HS-A5N7-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11185 isoform GeneRIF Biological Term Annotations 1.0 null abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.068263 L428 DepMap CRISPR Gene Dependency 1.0 2.79687 KLHDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66589 Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null leukocyte disease GWASdb SNP-Disease Associations 1.0 0.359119 hsa-miR-4468 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Age Related Macular Degeneration DisGeNET Gene-Disease Associations 1.0 null angle-closure glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.131 agreement GeneRIF Biological Term Annotations 1.0 null nonhispanic GeneRIF Biological Term Annotations 1.0 null NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1681 a95 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.712 KDSR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94234 TTLL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42308 regarding GeneRIF Biological Term Annotations 1.0 null Sensory system disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 ZNF430 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50475 within GeneRIF Biological Term Annotations 1.0 null VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46704 Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-491-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 nor GeneRIF Biological Term Annotations 1.0 null hsa-miR-3616-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 cohort GeneRIF Biological Term Annotations 1.0 null GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36789 DDX31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36069 examined GeneRIF Biological Term Annotations 1.0 null WM-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74259 chr10_122387175_A_T_b38 GTEx eQTL 2025 1.0 2.8042 weeks GeneRIF Biological Term Annotations 1.0 null H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null differentially GeneRIF Biological Term Annotations 1.0 null IKZF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64067 Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.39 exposure GeneRIF Biological Term Annotations 1.0 null ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.880723 conferred GeneRIF Biological Term Annotations 1.0 null Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04671 Lung adenocarcinoma_LUAD_TCGA-55-6968-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1258 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Blindness HuGE Navigator Gene-Phenotype Associations 1.0 null admixture GeneRIF Biological Term Annotations 1.0 null Retinal Hemorrhage HuGE Navigator Gene-Phenotype Associations 1.0 null implicate GeneRIF Biological Term Annotations 1.0 null GSE217541,GSE217543_3_v_2_tet1_human RummaGEO Gene Perturbation Signatures -1.0 null mitochondrion GO Cellular Component Annotations 2015 1.0 null revealed GeneRIF Biological Term Annotations 1.0 null differential GeneRIF Biological Term Annotations 1.0 null Optic Atrophy HuGE Navigator Gene-Phenotype Associations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7S9-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80961 excluded GeneRIF Biological Term Annotations 1.0 null GTEX-UPK5-2126-SM-4JBJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.01648 ADAM17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1056 MONOMAC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.68512 E2F8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97546 PATL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67096 subtypes GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GL-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 Membrane attack complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.204 GSE221327_6_v_11_clpp_human RummaGEO Gene Perturbation Signatures -1.0 null Photoreceptor inner segment COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 hematological neoplasm GWASdb SNP-Phenotype Associations 1.0 0.19282 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J6-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rad51C-XRCC3 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.607 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.47743 Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pathogenic GeneRIF Biological Term Annotations 1.0 null rose GeneRIF Biological Term Annotations 1.0 null KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04053 GATB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72717 fatty GeneRIF Biological Term Annotations 1.0 null NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01471 Angioid streaks DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.364 chr10_122384481_G_A_b38 GTEx eQTL 2025 1.0 2.15325 PMC9161725-Table_4.xlsx-EHF-CSAG1_EHF Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Outer nuclear layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.11 GNPDA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66227 tends GeneRIF Biological Term Annotations 1.0 null Alzheimer Disease HuGE Navigator Gene-Phenotype Associations 1.0 null SKMEL3 CCLE Cell Line Gene CNV Profiles -1.0 -1.39183 population GeneRIF Biological Term Annotations 1.0 null GSE119345_2_v_3_bexarotene_human RummaGEO Drug Perturbation Signatures -1.0 null Fundus albipunctatus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.112 transverse gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.933764 time GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cardiovascular Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-T6MO-1626-SM-32QOM GTEx Tissue Sample Gene Expression Profiles 1.0 0.849919 GTEX-PLZ4-2726-SM-3P61A GTEx Tissue Sample Gene Expression Profiles 1.0 0.929869 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.52611 Type 2 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.149 GTEX-PX3G-2026-SM-48U1H GTEx Tissue Sample Gene Expression Profiles 1.0 0.93029 Retinitis Pigmentosa DisGeNET Gene-Disease Associations 1.0 null DHDDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83184 fruits GeneRIF Biological Term Annotations 1.0 null antivascular GeneRIF Biological Term Annotations 1.0 null STAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55882 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.135 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05599 Basement membrane collagen trimer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.509 MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.956965 cancer GWASdb SNP-Disease Associations 1.0 0.073813 PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949558 GTEX-XUZC-1826-SM-4BRVO GTEx Tissue Sample Gene Expression Profiles 1.0 1.09655 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.67358 GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.16712 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851606 polymorphism GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STX16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0023 DIS3L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22303 CSRNP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99177 dietary GeneRIF Biological Term Annotations 1.0 null correlation GeneRIF Biological Term Annotations 1.0 null disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.397419 GTEX-X4EO-2726-SM-4E3HS GTEx Tissue Sample Gene Expression Profiles 1.0 1.15662 DHX9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89795 Microfibril COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.001 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11138 KASUMI1 CCLE Cell Line Gene CNV Profiles 1.0 1.34554 ovary GTEx Tissue Gene Expression Profiles 1.0 1.46362 PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY Rummagene Transcription Factor Associations 2026 1.0 null alter GeneRIF Biological Term Annotations 1.0 null DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1301 abnormality of the skeletal system GWASdb SNP-Phenotype Associations 1.0 0.101442 contributors GeneRIF Biological Term Annotations 1.0 null SNU478 CCLE Cell Line Gene CNV Profiles 1.0 2.01007 Diabetic retinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.344 account GeneRIF Biological Term Annotations 1.0 null MRPL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46812 Stargardt disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.067 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.85172 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.853612 geneticsdemographics GeneRIF Biological Term Annotations 1.0 null find GeneRIF Biological Term Annotations 1.0 null bronchial disease GWASdb SNP-Disease Associations 1.0 0.95488 MT-ND4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28111 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.8699 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.51403 Growth factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.42 showed GeneRIF Biological Term Annotations 1.0 null obesity GWASdb SNP-Disease Associations 1.0 0.892579 pseudodrusen GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of anatomical entity DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 GTEX-SNMC-1226-SM-2XCFP GTEx Tissue Sample Gene Expression Profiles 1.0 0.976568 H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null brain GeneRIF Biological Term Annotations 1.0 null MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.891545 VKORC1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24792 mice GeneRIF Biological Term Annotations 1.0 null Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.408 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null XPO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06451 Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vision HuGE Navigator Gene-Phenotype Associations 1.0 null IER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59951 Fever DisGeNET Gene-Phenotype Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Z-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null family GeneRIF Biological Term Annotations 1.0 null apolipoprotein a-i GAD Gene-Disease Associations 1.0 null KIFBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42997 either GeneRIF Biological Term Annotations 1.0 null letter GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QZ-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.912 WWP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89614 H2BK20ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.826231 GTEX-U3ZN-1026-SM-4DXTC GTEx Tissue Sample Gene Expression Profiles 1.0 1.00734 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-7332-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSN1 CCLE Cell Line Gene CNV Profiles 1.0 1.37771 Rheumatoid arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.02 ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 68.526 Photoreceptor outer segment membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.604 TRMT44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73387 GTEX-QCQG-1326-SM-48U24 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12896 all GWASdb SNP-Phenotype Associations 1.0 0.239387 Physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 PMC9170110-pgen.1010161.s047.xlsx-DBP_DEP-nearestGene_DBP Rummagene Transcription Factor Associations 2026 1.0 null nucleus of Darkschewitsch, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38501 FAM98C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96323 SH3BGRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54596 rs1048661 GeneRIF Biological Term Annotations 1.0 null CPSF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56669 Lung squamous cell carcinoma_LUSC_TCGA-60-2708-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TTLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23845 MTA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73974 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.79355 geographic atrophy; macular degeneration GAD Gene-Disease Associations 1.0 null NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78316 increasing GeneRIF Biological Term Annotations 1.0 null normal GeneRIF Biological Term Annotations 1.0 null Polyps HuGE Navigator Gene-Phenotype Associations 1.0 null nervous system disease GWASdb SNP-Disease Associations 1.0 1.34993 GATA6-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null retina GeneRIF Biological Term Annotations 1.0 null Other source TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.273 sample GeneRIF Biological Term Annotations 1.0 null Sclera TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.093 IZ in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21051 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 248.489 based GeneRIF Biological Term Annotations 1.0 null Retina TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Macular Degeneration dbGAP Gene-Trait Associations 1.0 3.12841 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.7855 ZNF541 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39605 plasma GeneRIF Biological Term Annotations 1.0 null seem GeneRIF Biological Term Annotations 1.0 null Vasculature TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.789 Retinal pigment epithelium cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.148 wild GeneRIF Biological Term Annotations 1.0 null ABTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98082 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null indian GeneRIF Biological Term Annotations 1.0 null previously GeneRIF Biological Term Annotations 1.0 null Age-related macular degeneration GWAS Catalog SNP-Phenotype Associations 1.0 3.37239 MKRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15339 Retinal pigment epithelium TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-TMZS-0226-SM-3DB9N GTEx Tissue Sample Gene Expression Profiles 1.0 0.911039 LDOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32933 Sensillum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.576 RITS complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.252 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64302 GMCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18852 general GeneRIF Biological Term Annotations 1.0 null Lens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.442 GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.862483 SNX21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8629 Retinal Drusen HuGE Navigator Gene-Phenotype Associations 1.0 null mtndh2 GeneRIF Biological Term Annotations 1.0 null due GeneRIF Biological Term Annotations 1.0 null medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.988344 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles 1.0 0.863662 polymorphisms GeneRIF Biological Term Annotations 1.0 null abnormality of the globe GWASdb SNP-Phenotype Associations 1.0 1.94642 impacts GeneRIF Biological Term Annotations 1.0 null Scotoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.126 Venous blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.472 Conjunctiva TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.209 etiologic GeneRIF Biological Term Annotations 1.0 null Polygenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.109 POGLUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80085 retinal disease GWASdb SNP-Disease Associations 1.0 2.41089 Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.109 outer CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08267 contribution GeneRIF Biological Term Annotations 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01689 H2BC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10194 cytosol GeneRIF Biological Term Annotations 1.0 null choroidal GeneRIF Biological Term Annotations 1.0 null Y79 DepMap CRISPR Gene Dependency 1.0 5.87672 GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 1.58229 Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.9207