association dataset threshold value standardized value small intestine epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.187095 SPI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62119 PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null mouth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.457864 GSE94849_7_v_2_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null edman Phosphosite Textmining Biological Term Annotations 1.0 null calcium-calmodulin-dependent-protein-kinases Phosphosite Textmining Biological Term Annotations 1.0 null HINFP JASPAR Predicted Transcription Factor Targets 1.0 null Basal ganglion TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.016 OVCAR3 BioGPS Cell Line Gene Expression Profiles 1.0 1.11261 Caudate nucleus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.016 NCIH292 CCLE Cell Line Gene Expression Profiles -1.0 -1.52423 BRD-K71631414 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30548 motor cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.684327 OE33 DepMap CRISPR Gene Dependency 1.0 4.74648 Ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.99 GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.863291 vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.618406 arpp21 GeneRIF Biological Term Annotations 1.0 null GTEX-WFJO-0926-SM-4LVM2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-124-3p MiRTarBase microRNA Targets 1.0 null BRD-K89550909 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06277 20502458-TableS6b GeneSigDB Published Gene Signatures 1.0 null Basal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.05 pharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067487 CRCGN015_MCF10A.TP53.M_24H:L19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.13445 KNS-62 GDSC Cell Line Gene Expression Profiles -1.0 -1.66782 GTEX-QMR6-0011-R6A-SM-32PKP GTEx Tissue Sample Gene Expression Profiles 1.0 2.37068 Depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 root tip TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.177334 NR4A2-19515692-MN9D-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Anteromedial visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20138 spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.246046 BRD-K44787496 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05348 GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles 1.0 0.8369 mesenchymal cell neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.171535 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Posterior cardinal vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788 olanzapine_rattus norvegicus_gds2608 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null REST ChEA Transcription Factor Targets 1.0 null GTEX-POMQ-0526-SM-3GADD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K48739735 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14116 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AF-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K96567801 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1952 CASTOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01382 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.28144 GSE120336_0_v_2_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Hemorrhage CTD Gene-Disease Associations 1.0 1.45141 BRD-K66526269 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43705 Pons TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.166 DES_KO_GDS4804_171_mouse_young skeletal muscles GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23362 ECC12 CCLE Cell Line Gene CNV Profiles 1.0 1.43463 periventricular stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7456 Basolateral amygdalar nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05471 axon part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.104417 GTEX-QDVN-1026-SM-48TZA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.139266 hsa-miR-3143 TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 lymphoblastic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067678 MSI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45606 Perturb_15116_KD_Rtn4_SRP278924 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5932 telangiectasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.227642 CAL33 CCLE Cell Line Gene CNV Profiles -1.0 -1.72534 SNU1327 DepMap CRISPR Gene Dependency 1.0 2.27649 GSE124932_2_v_1_sarm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ATF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43921 Hypertrophy CTD Gene-Disease Associations 1.0 1.63138 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.257907 SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TCF12/HEB-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-548o TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null OVCA420 DepMap CRISPR Gene Dependency 1.0 3.68085 PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null PMC7825356-8844261.f3.docx-247-NR1D2_NR1D2 Rummagene Transcription Factor Associations 2026 1.0 null r3 part of vestibular sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10474 Perturb_5476_OE_Sox9_SRP375106 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.55708 Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUZ domain InterPro Predicted Protein Domain Annotations 1.0 null GSE120200,GSE127269_1_v_2_asxl1_human RummaGEO Gene Perturbation Signatures -1.0 null Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.48672 BRD-K90205159 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1574 PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-RNA-Seq_analysis_of_genes_associated_with_a_DHS_that_has_a_CEBPAx2_specific_Hi-C_interaction_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null Brain Diseases CTD Gene-Disease Associations 1.0 1.17827 periventricular stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18156 Impaired Cognition DisGeNET Gene-Disease Associations 1.0 null acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.250839 Nuclear exosome (RNase complex) COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.129 PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_13412_KD_Ppp3cc_SRP193770 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 striatal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.407832 ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0541 NCI-H2135 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-133b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 hsa-miR-4658 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE138841_0_v_1_trim6_human RummaGEO Gene Perturbation Signatures -1.0 null AGO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77238 cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.603596 Prelimbic cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.575 ventrolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.912441 reticulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.396465 BRD-K46311453 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05985 skeletalmuscle_a HPA Tissue Sample Gene Expression Profiles 1.0 1.12853 TLX1_01_246 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.94742 BRD-K16406336_METHYLENE BLUE_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null malaria DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.228679 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K76694128_DCC-2036_MCF7_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE79663_2_v_0_tcf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null calcineurin Phosphosite Textmining Biological Term Annotations 1.0 null BRD-K92632379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26628 layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10797 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.957856 GSE234043_3_v_1_abcb1_human RummaGEO Gene Perturbation Signatures -1.0 null BRD-K96776591 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59819 Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.578 urinary bladder HPA Tissue Gene Expression Profiles -1.0 -1.29832 GTEX-QV31-0226-SM-447BO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-N7MS-0011-R8a-SM-2YUMK GTEx Tissue Sample Gene Expression Profiles 1.0 0.928907 GSE149880_0_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null cellular process GO Biological Process Annotations 2015 1.0 null GTEX-WZTO-0011-R5B-SM-3NMC5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.69191 GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 0.980123 GSE129241_4_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-S3XE-0126-SM-4AD4R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 lymphocytic leukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.52401 SNB75 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_15619_Mut_Dmd_SRP329695 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.30618 primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.85971 Perturb_4200_KD_Mecp2_SRP072951 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 SNU601 CCLE Cell Line Gene CNV Profiles -1.0 -1.69965 GSE129241_4_v_6_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null Mild cognitive impairment DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.059 VZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.971575 GSE126127_0_v_1_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K38035271 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20483 Piriform area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.872 GTEX-WVLH-0011-R10A-SM-3MJFM GTEx Tissue Sample Gene Expression Profiles 1.0 0.939962 CRCGN016_MCF10A.TP53.M_24H:O21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.7701 GTEX-SNMC-0826-SM-4DM66 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4271 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GTEX-R55E-0008-SM-48FCG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GTEX-PWN1-0008-SM-48TEA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.54321 GSE132948,GSE132949_0_v_5_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null SON_KD_GDS4448_35_human_HeLa GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y5-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.88537 GSE135350_3_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5713-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.099427 Perturb_4323_OE_Fos_SRP075838 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 17.4868 BRD-K64345025 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07696 GSU CCLE Cell Line Gene CNV Profiles 1.0 2.15738 IL17RA LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00448976 Bunina body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.126 Acute leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 UBE2F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62849 BRD-K51919278 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79695 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5419 PRDM14-20953172-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5882 primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.26798 GSE111660_2_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.403438 IPF1 MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K56870337 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23757 GSE123943_1_v_0_sox1_human RummaGEO Gene Perturbation Signatures 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.0845 practolol-5664 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE122509,GSE122513_2_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE209598_1_v_2_tgfbr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null cerebralcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.0427 Piriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22139 iPS-18 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.35436 carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057066 GSE119498_6_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null MRFAP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18813 MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 ZNF573 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00468773 BRD-K36493118 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05994 GTEX-WFG8-0001-SM-4LVN8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null GSE142684_3_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Caudatenucleus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 BRD-K03421365 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2369 mantle zone of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02289 camp Phosphosite Textmining Biological Term Annotations 1.0 null Basal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.619 GTEX-R55E-0011-R6A-SM-2TC5T GTEx Tissue Sample Gene Expression Profiles 1.0 2.01761 GSE126345_2_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46532 BRD-K86268010 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2952 OCILY10 CCLE Cell Line Gene CNV Profiles 1.0 1.52485 GTEX-T6MN-0011-R7A-SM-32QP5 GTEx Tissue Sample Gene Expression Profiles 1.0 2.29756 periodontitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.516494 GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.06592 GSE132948,GSE132949_0_v_3_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null LTB4R2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00591258 BRD-K14246348 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12521 PMC8554124-DataSheet2.XLSX-34-RFX3_RFX3 Rummagene Transcription Factor Associations 2026 1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.996176 AP-1 MotifMap Predicted Transcription Factor Targets 1.0 null superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08089 BRD-K97081185 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.3686 GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.966196 liposarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.123981 GTEX-WVLH-0011-R6A-SM-3MJFZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.64449 GTEX-TKQ2-0426-SM-4DXUO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 SPI1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-2526-SM-2TC6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.05763 tetanus DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.202618 Amyotrophic Lateral Sclerosis DisGeNET Gene-Disease Associations 1.0 null photosystem i COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.26656 GTEX-T5JC-0011-R7A-SM-32PME GTEx Tissue Sample Gene Expression Profiles 1.0 1.78198 Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.027 body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57546 BRD-K43287163 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58127 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.806 BRD-K40282027 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52106 GSE213588_9_v_7_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null E2F4-17652178-JURKAT-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE106661,GSE106665_0_v_3_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null BCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47916 lymphadenitis GWASdb SNP-Disease Associations 1.0 0.775452 peripheral blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.364513 NCIH226 DepMap CRISPR Gene Dependency 1.0 5.19742 Weight Loss CTD Gene-Disease Associations 1.0 1.94343 hsa-miR-548an TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 Nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.106 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-Q2AI-0426-SM-48U13 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.869418 tail of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42935 GSE89057_0_v_1_sox5_human RummaGEO Gene Perturbation Signatures -1.0 null Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.025 hsa-miR-15b TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR Rummagene Transcription Factor Associations 2026 1.0 null caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.31589 SET-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.53 IRF8 ChEA Transcription Factor Targets 1.0 null HS766T COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE107854_2_v_0_prmt5_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-144 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.051644 developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.197099 GTEX-U4B1-1026-SM-4DXT1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 response to abiotic stimulus GO Biological Process Annotations 2015 1.0 null sensillum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.459532 GSE94814_2_v_3_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE240896,GSE240899_2_v_0_ccnt1_human RummaGEO Gene Perturbation Signatures -1.0 null CRCGN016_MCF10A.TP53.M_24H:A19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.67164 RS411 CCLE Cell Line Gene Expression Profiles 1.0 2.65489 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in rostral cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.186 GSE175787_8_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE150665,GSE150667_4_v_0_mysm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null spleen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.24486 Nodulus (X) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.08708 POLR2A_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K17743125_belinostat_PC3_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hsa-miR-4330 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null dose-response-relationship-drug Phosphosite Textmining Biological Term Annotations 1.0 null NCI-H727 COSMIC Cell Line Gene Mutation Profiles 1.0 null cystic kidney DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.185313 orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.42339 VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28778 intestinal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.398735 PPARD ChEA Transcription Factor Targets 1.0 null GTEX-OHPL-2426-SM-48TDN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Corpus striatum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.016 HEB MotifMap Predicted Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55G-0126-SM-48FDS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE229468,GSE229471_2_v_1_znf587_human RummaGEO Gene Perturbation Signatures 1.0 null fluoxetine_mus musculus_gpl1261_gds2803 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-NPJ8-0126-SM-2YUNR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.630314 Perturb_565_KO_NRAS_SRP158623 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 HS172T CCLE Cell Line Gene Expression Profiles -1.0 -1.50571 A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.52541 toxic shock syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.18151 ahr_19454665_epidermal_langerhans_cell_lof_mouse_gpl339_gds3575 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.13686 Perturb_9831_KO_SIX6_SRP256351 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 striatum_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.29783 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07236 GSE180185_4_v_1_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null General risk tolerance (MTAG) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.969897 BRD-K95350313 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00557 GSE94849_7_v_5_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20621 respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.351923 GYPB LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0075858 CRCGN016_MCF10A.TP53.M_24H:G10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.8127 interneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.77857 GSE111660_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Learning Disorders CTD Gene-Disease Associations 1.0 1.68084 MGME1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43009 LS123 DepMap CRISPR Gene Dependency 1.0 2.75719 PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-Symbol_FOXO3 Rummagene Transcription Factor Associations 2026 1.0 null heart TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.246124 BRD-K72681425 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14766 GSE115542_2_v_3_digoxin_human RummaGEO Drug Perturbation Signatures 1.0 null Lobule II, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1932 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.49674 BRD-K22725588 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16328 19185848-TableS1 GeneSigDB Published Gene Signatures 1.0 null GSE182680,GSE182683_5_v_8_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PWCY-0008-SM-48TE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Perturb_14003_OE_Kcna2_SRP309478 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.4892 BRD-K50876388 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60474 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.09191 GSE210101,GSE210114_5_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null head of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86709 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_1169_KD_CBFB_ERP128097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46363 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50334 GTEX-XUJ4-0226-SM-4BOP8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 1.58232 Medium spiny neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.773 lacrimal apparatus disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.070415 BUD23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07449 BRD-K41878930 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53246 kidney TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K17238328 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19713 GTEX-R3RS-0626-SM-48FE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K44722328 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37983 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36224 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null BRD-K56179613 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48081 GSE145915_0_v_2_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.775928 Perturb_4474_OE_Smn_SRP258674 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.7568 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.43274 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.938706 BRD-K55187425_ON-01910_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K45282594 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28324 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null extensor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.43989 GSE208254_4_v_5_irf8_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K79937035 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16417 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0576 SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ACYP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09156 Primary Malignant Neoplasm Of Lung DisGeNET Gene-Disease Associations 1.0 null GSE126345_7_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36871 BRD-K25226763 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.25704 GTEX-T5JW-0008-SM-4DM5X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.033 TRRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24293 parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.991469 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K99749624_S1003_HCC515_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Diencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03877 hsa-miR-4530 TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.19813 BRD-K09991945_GSK-3 Inhibitor II_A375_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null VRK1 Kinase Library Serine Threonine Kinome Atlas 1.0 null BL1804 (MTA1) NURSA Protein Complexes 1.0 null Coronary Heart Disease DisGeNET Gene-Disease Associations 1.0 null GTEX-RNOR-0008-SM-48FEY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.68269 Perturb_11890_OE_Ddah1_SRP027595 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.05196 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE126345_11_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4892 GTEX-WFJO-0008-SM-4LVN7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K87537204 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31668 retinal degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.258064 reticular nucleus of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.906605 SALL4 ChEA Transcription Factor Targets 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.733 Kidney Diseases CTD Gene-Disease Associations 1.0 1.46515 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PLZ6-1426-SM-2S1OQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 mRNA_SMAD4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null aorta thoracica TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.275794 SUP-T1 GDSC Cell Line Gene Expression Profiles 1.0 1.48969 Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1224-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE123002_0_v_1_srsf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Injuries CTD Gene-Disease Associations 1.0 1.07234 phycobiont TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.326798 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.56299 Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Up_HES4 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K39397248 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00304 granulocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.322414 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.956768 Chronic lymphocytic leukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42514 BRD-A38066207 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15793 Gender incongruence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.153 pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.13335 hsa-miR-195 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 GTEX-XV7Q-2526-SM-4BRV9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 x63ag8.653 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.659 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02289 Glucose Intolerance CTD Gene-Disease Associations 1.0 1.09786 IFNA8 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00568307 nh2-terminal Phosphosite Textmining Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IL2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00669712 YANK2 Kinase Library Serine Threonine Kinome Atlas 1.0 null Apical dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.93 GTEX-WFJO-0326-SM-3GIL3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 CALU1 CCLE Cell Line Gene CNV Profiles 1.0 1.5641 Coronary Artery Disease DisGeNET Gene-Disease Associations 1.0 null GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles 1.0 0.851105 substance-related disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.065391 GTEX-QMR6-0008-SM-447AV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.843306 GSE109530,GSE109531_1_v_3_hdac3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061061 GSE182680,GSE182683_10_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K97452545 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.93755 GSE120612_7_v_0_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_15862_KD_KDM3A_SRP270313 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.500398 GTEX-V955-1826-SM-4JBIL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.394661 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.19283 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.01982 RD CCLE Cell Line Gene Expression Profiles 1.0 2.13764 Perturb_328_KD_GDF15_SRP201220 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.72442 effector Phosphosite Textmining Biological Term Annotations 1.0 null Autolysosome membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.679 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_9026_KD_lncFAM_SRP377217 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.32115 flower TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.541377 tibialis anterior TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.468824 BRD-K22145792 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14479 r4 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74736 GTEX-P44H-0426-SM-2XCEZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.22287 albendazole-oxide LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.90608 autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.175947 BRD-A45498368_WYE-125132_MCF7_3_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-0011-R1A-SM-2TC6N GTEx Tissue Sample Gene Expression Profiles 1.0 0.833547 biofilm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.31018 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-1926-SM-4BOOV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9942321-12916_2023_2766_MOESM1_ESM.xlsx-S9-Supplementary_Table_9_DEGs_distributed_per_SOM_profile_in_all_IS_etiologies_based_on_Euclidean_distance_GRHL3 Rummagene Transcription Factor Associations 2026 1.0 null SETBP1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00622146 ARMCX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06714 cell type benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.585108 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.41082 769-P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28564 GTEX-PWN1-0626-SM-48TDT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE160817_5_v_1_slamf6_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-POMQ-0008-SM-48TE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2405 PMC8803621-mmc6.xlsx-Sup_Fig5A_genes_list-Genes_with_following_MEF2_motifs_around_their_TSS_CTAWWWATA_RSRFC4_Q2_MEF2_Q6_01_MEF2_03_MEF2_02_RSRFC4_Q2_from_GSEA_MEF2A Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.937147 prostate_a HPA Tissue Sample Gene Expression Profiles 1.0 0.915372 hsa-miR-4659b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Mouse - Motor Cortex - Class - Glutamatergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null BRD-K57468571 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08358 mRNA_WHSC2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_38_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null open-angle glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.138269 GSE210101,GSE210114_2_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null TERF1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S7SF-2026-SM-3K2AS GTEx Tissue Sample Gene Expression Profiles 1.0 1.21351 Sepsis_Splenocyte_GSE4479 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.37151 GTEX-UJMC-1826-SM-3GADT GTEx Tissue Sample Gene Expression Profiles 1.0 0.881106 basointermediate isthmic reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03161 RL CCLE Cell Line Gene Expression Profiles 1.0 1.68586 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05238 seed TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.700262 GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.987076 cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.43725 GSE128076_2_v_3_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.844652 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null renal carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.967921 RS4-11 GDSC Cell Line Gene Expression Profiles 1.0 3.59522 replication compartment COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.06549 G120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.933836 AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1297 T84 CCLE Cell Line Gene CNV Profiles 1.0 1.87204 smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.142031 GSE120612_4_v_5_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70222 CUX1 ChEA Transcription Factor Targets 1.0 null hsa-miR-3660 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 NZM3 DepMap CRISPR Gene Dependency 1.0 3.61528 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.07176 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1943 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.301054 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3571 GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.83501 Primary T cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.891398 reh cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.251934 GSE150055_0_v_2_melphalan_human RummaGEO Drug Perturbation Signatures -1.0 null occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17797 axon collateral COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.470005 H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_16888_OE_Sca17_SRP248035 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.87005 PLD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04502 CDC14C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63896 Human - Bone Marrow - L2 - Precursor B HuBMAP Azimuth Cell Type Annotations 1.0 null DBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59702 blood vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.711729 GSE210101,GSE210114_8_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.09074 clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.349 GTEX-TSE9-0011-R7A-SM-3DB7P GTEx Tissue Sample Gene Expression Profiles 1.0 1.44253 GTEX-TKQ2-0226-SM-4DM6V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-QMRM-0008-SM-447B1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-T5JC-1726-SM-4DM6U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null Uterine Cervical Neoplasms CTD Gene-Disease Associations 1.0 1.15256 GSE231720,GSE231724_3_v_0_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null CH157MN CCLE Cell Line Gene CNV Profiles 1.0 3.2803 Perturb_1171_KD_RUNX1_ERP128097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 BLZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5888 blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052363 vena cava TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.181421 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.14685 GSE128634,GSE128636_1_v_0_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null BRD-K78218619 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45069 HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null EIF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45553 BRD-K82521348 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05253 BRD-K67725403 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02262 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.734323 Proteasome activator complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.733 BRD-K45974539 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03775 replisome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.476831 ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03743 NFI-21473784-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-QEG5-1426-SM-447AS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 zona reticulata TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.21883 PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-Unnamed_0_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null CAL120 CCLE Cell Line Gene CNV Profiles -1.0 -1.49223 hsa-miR-539 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Right middle cerebral artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.658 Fastigial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75754 BRD-K01834163_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null immunodeficiency-centromeric instability-facial anomalies syndrome 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.066 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.342233 GTEX-WZTO-0011-R4A-SM-3NMC7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.945324 BRD-K54694941 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58491 BRD-K73296174 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22622 abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.097715 HT29 CCLE Cell Line Gene Expression Profiles -1.0 -1.83509 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.09539 CIAO2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04757 COGE352 DepMap CRISPR Gene Dependency 1.0 2.76461 GSE150665,GSE150667_1_v_5_mysm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null glomerulonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.079975 GTEX-TSE9-0011-R6A-SM-3DB7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.9199 BRD-K69840642_HDAC6 inhibitor ISOX_JHUEM2_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null neonate TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.215147 GSE182680,GSE182683_7_v_11_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WFJO-0226-SM-3GIKW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-3166 TargetScan Predicted Conserved microRNA Targets 1.0 0.389112 Cardiovascular Abnormalities CTD Gene-Disease Associations 1.0 1.04465 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-A99750020 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18362 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4927 envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.269701 GTEX-QVJO-1826-SM-447C9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.198658 PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL1-OVERLAP_GENES_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1 Rummagene Transcription Factor Associations 2026 1.0 null ZNF737 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84174 cytoplasmic vesicle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.583431 LNCAPCLONEFGC CCLE Cell Line Gene Expression Profiles -1.0 -1.59693 GAMG COSMIC Cell Line Gene Mutation Profiles 1.0 null Locus ceruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21803 neuron part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.059828 GSE222445_2_v_1_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null CRCGN016_MCF10A.TP53.M_24H:O11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.86735 GSE116810_2_v_3_selinexor_human RummaGEO Drug Perturbation Signatures 1.0 null GSE133087_1_v_0_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K85493820_KM 00927_HCC515_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K75806288 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05961 GTEX-XV7Q-1626-SM-4BRWC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 all GWASdb SNP-Phenotype Associations 1.0 0.037243 primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.865703 BRD-K85357344 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42242 thylakoid membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.680284 STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null Posterolateral visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31829 GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.07227 CCL1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00457981 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.752 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929629 GR MotifMap Predicted Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2466 GSE169152_3_v_1_ibrutinib_human RummaGEO Drug Perturbation Signatures -1.0 null COLO680N CCLE Cell Line Gene Expression Profiles -1.0 -1.54484 C2CD2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51731 GTEX-PLZ5-0926-SM-3TW8L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE164874_5_v_2_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null filament TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.326798 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.43042 mucous gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.475423 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4823-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.222224 Neuron_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45418 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.55746 SNU1214 CCLE Cell Line Gene CNV Profiles -1.0 -1.41769 frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.35557 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.08187 TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.56 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00045 NCIH1436 CCLE Cell Line Gene CNV Profiles -1.0 -1.45586 Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Whipple's Disease_macrophage_GSE16180 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.4976 GSE171177,GSE171181_1_v_2_e7107_human RummaGEO Drug Perturbation Signatures -1.0 null Entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.206 GTEX-T2IS-0826-SM-4DM6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16472 GSE231524,GSE231526_0_v_1_dusp6_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18986 Neurotoxicity Syndromes CTD Gene-Disease Associations 1.0 1.03345 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles 1.0 1.16248 basomedial amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00955 CDIPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71672 primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16734 gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GSE160817_3_v_6_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null ARL5C LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00565989 hsa-miR-16 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OV-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1260 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 BRD-K49371609_528116.cdx_EFO27_6.0_h_0.09_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Human - Tonsil - L1 - preB/T HuBMAP Azimuth Cell Type Annotations 1.0 null Pyramidal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.504 BRD-K43000271 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4977 GSE137914_0_v_1_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.333763 H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.08811 BB30-HNC GDSC Cell Line Gene Expression Profiles -1.0 -1.5852 GSE147662_3_v_5_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5018 GTEX-XOTO-0011-R6B-SM-4B65X GTEx Tissue Sample Gene Expression Profiles 1.0 1.50758 layer 1 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48536 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null macrophage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.35743 Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-XQ8I-2026-SM-4BOOL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Oligodendroglioma DisGeNET Gene-Disease Associations 1.0 null GTEX-UTHO-0011-R5A-SM-3GIJD GTEx Tissue Sample Gene Expression Profiles 1.0 2.30762 BRD-K84233319 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59766 GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-WFG7-0426-SM-4LMK5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K05286676 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03309 GSE94849_7_v_4_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null GSE155305_2_v_1_ifitm3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OHPM-0526-SM-2YUMJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11134 GTEX-T5JC-0011-R8A-SM-32PLM GTEx Tissue Sample Gene Expression Profiles 1.0 1.01418 BRD-K44861255 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02795 BRD-K44759088 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40398 Muscle-fast muscle cell Tabula Sapiens Gene-Cell Associations 1.0 0.227822 GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles 1.0 1.01972 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.883357 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE120612_7_v_5_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066348 urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050729 BRD-K88099511 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.46649 bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.74174 SCCPDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62509 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.72507 posteromedial visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41599 GTEX-T6MO-0008-SM-4DM6T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE71100_0_v_1_lin28b_human RummaGEO Gene Perturbation Signatures 1.0 null stomach TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.322779 HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26459 Cognitive performance GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.669897 chr3_35594324_C_CTT_b38 GTEx eQTL 2025 1.0 2.79644 KOPN8 CCLE Cell Line Gene Expression Profiles 1.0 1.55035 GTEX-RU72-0011-R7A-SM-2TF5U GTEx Tissue Sample Gene Expression Profiles 1.0 1.35587 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GSE196962_4_v_3_parg_human RummaGEO Gene Perturbation Signatures -1.0 null temporal lobe TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ventropallial prepiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16543 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.824216 Fever CTD Gene-Disease Associations 1.0 1.05793 BRD-A60245366_-666_VCAP_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K21897482 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73768 TEAD1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00436642 commensal bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.085087 rectus femoris TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.382884 posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.837641 HEKTE CCLE Cell Line Gene Expression Profiles -1.0 -1.89032 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26776 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null HCE4 DepMap CRISPR Gene Dependency 1.0 8.25004 GBF1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00534792 orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20113 plague DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.236312 PTPRH LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00532482 Diencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.693 TAL1 MotifMap Predicted Transcription Factor Targets 1.0 null RPL26L1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00721147 Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null renal glomerular capsule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.197695 PANC-03-27 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QEL4-2126-SM-447AE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.976341 PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null cellular response to stimulus GO Biological Process Annotations 2015 1.0 null GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 1.04263 hsa-miR-9 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 MMAC-SF COSMIC Cell Line Gene CNV Profiles 1.0 2.14116 16151515-TableS3 GeneSigDB Published Gene Signatures 1.0 null mRNA_ASCL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XC-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.634 VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54968 BRD-K90808566 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3859 GSE182680,GSE182683_0_v_9_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB5_CREB5 Rummagene Transcription Factor Associations 2026 1.0 null Gfi1b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.6269 myeloid progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069216 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-T6MN-0011-R11A-SM-32QOX GTEx Tissue Sample Gene Expression Profiles 1.0 1.1296 psii associated light-harvesting complex ii COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.584686 GTEX-XUJ4-1226-SM-4BOPD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE210101,GSE210114_6_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null CDH6 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00557323 plant form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.791877 GTEX-OXRN-0011-R5A-SM-2I5EF GTEx Tissue Sample Gene Expression Profiles 1.0 1.39207 Diabetes DisGeNET Gene-Disease Associations 1.0 null TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16049 PMC4823079-oncotarget-07-2889-s002.xls-Feuil3-Supplementary_table_1_DEK_and_WT1-dependent_AEUs_WT1 Rummagene Transcription Factor Associations 2026 1.0 null tooth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.495411 GSE168401_1_v_0_harmine_human RummaGEO Drug Perturbation Signatures -1.0 null Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04078 GSE210101,GSE210114_2_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF354C JASPAR Predicted Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K83815133 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27067 hsa-miR-4326 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null Immune System Diseases CTD Gene-Disease Associations 1.0 1.02262 SEM CCLE Cell Line Gene Expression Profiles 1.0 3.40641 BRD-K29543978 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31427 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null A4 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.99588 Feeling worry GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.81549 superficial stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1683 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4102-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE182680,GSE182683_5_v_12_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05869 CESS COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-NPJ8-1726-SM-2YUNB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7173 GTEX-N7MT-0011-R7a-SM-2I3FZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.54676 GSE169152_3_v_2_ibrutinib_human RummaGEO Drug Perturbation Signatures -1.0 null HSP90AB1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00382626 SNB19 BioGPS Cell Line Gene Expression Profiles -1.0 -0.942855 GTEX-QVUS-0011-R10A-SM-3GIK3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.850672 hippocampus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-Q2AG-0011-R5A-SM-2HMJH GTEx Tissue Sample Gene Expression Profiles 1.0 1.84599 PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.68188 GTEX-T5JC-2326-SM-32PMR GTEx Tissue Sample Gene Expression Profiles 1.0 1.14053 fluoxetine_mus musculus_gpl1261_gse35761 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ATF7 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00661806 GSE116810_5_v_3_selinexor_human RummaGEO Drug Perturbation Signatures -1.0 null Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CRCGN014_HEPG2_3H:K02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.02179 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.19593 SW13 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.86734 mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.80487 peripheral vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.077347 Perturb_1434_KO_Kmt2c_SRP283007 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.01936 CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Peripheral Nervous System Diseases CTD Gene-Disease Associations 1.0 1.09226 capillary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.223906 Perturb_1176_KD_RUNX1_ERP128097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 blood cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ELF4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00572002 Perturb_1175_KD_CBFB_ERP128097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20373 Myelencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.299 BRD-K33906096 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08788 Perturb_6340_KO_Nrtn_SRP273435 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.46893 KCND1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00483311 fruit TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.346668 Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC9883165-41375_2022_1744_MOESM4_ESM.xlsx-CEBP_gene_module-Unnamed_1_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null tuberous sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.21565 PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10809 Avian pallium TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Postpiriform transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25468 FADU COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K36170990 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1277 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.269753 H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-REY6-1326-SM-48FDO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles 1.0 1.03118 GSE219195_4_v_5_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-T6MO-1226-SM-4DM5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE145215_0_v_1_krt13_mouse RummaGEO Gene Perturbation Signatures -1.0 null CRCGN015_MCF10A.TP53.M_24H:P13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.36395 CRCGN008_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.576 Hippocampal pyramidal layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.504 Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16276 GSE175571_3_v_2_acsl6_mouse RummaGEO Gene Perturbation Signatures 1.0 null OCI-AML5 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RTLS-0008-SM-48FET GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 photosystem ii oxygen evolving complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.606973 SOX2 ChEA Transcription Factor Targets 1.0 null Age at first sexual intercourse GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1 plasmacytoid t-lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.43146 GTEX-U412-2026-SM-4DXSI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.09796 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7502-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20138 ZNF384_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null honey TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.540585 intracellular part GO Cellular Component Annotations 2015 1.0 null GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01733 GSE233647_4_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-K76415725 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45124 PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Embryo Loss CTD Gene-Disease Associations 1.0 1.02225 hsa-miR-3667-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 plasma membrane-derived chromatophore COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.39851 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1 Rummagene Transcription Factor Associations 2026 1.0 null trypsin Phosphosite Textmining Biological Term Annotations 1.0 null intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.575216 A4-FUK COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN015_MCF10A.WT.HP_24H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.13775 myositis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.099916 al Phosphosite Textmining Biological Term Annotations 1.0 null avian pallium TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2816 GSE118939_1_v_0_nras_human RummaGEO Gene Perturbation Signatures 1.0 null DBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99375 PLPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12236 GSE188870,GSE188871_1_v_5_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Tea consumption GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 GTEX-U3ZH-0926-SM-4DXU4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09865 GSE111061_1_v_3_tofacitinib_human RummaGEO Drug Perturbation Signatures -1.0 null Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.8174 GSE126127_0_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CDK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07411 GATA2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00361962 recurrent axon collateral COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.525931 Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.0801 GTEX-RWSA-0008-SM-47JYX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K99125195 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0596 GSE120612_6_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K91654198 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.29749 GSE128634,GSE128636_4_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null BRD-K22875057 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17689 CCK81 DepMap CRISPR Gene Dependency 1.0 4.93147 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8314 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5099-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PSDG-1626-SM-48TCQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 immune system disease GWASdb SNP-Disease Associations 1.0 0.056104 inner CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.895102 basal ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-OOBK-1026-SM-48TC2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 mononuclear cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.299242 GSE144120_3_v_1_plcg2_human RummaGEO Gene Perturbation Signatures 1.0 null BRD-K79090631_CGP-60474_MCF7_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Liver GTEx Tissue Gene Expression Profiles 2023 1.0 3.20473 locus ceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.55045 VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10993 GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02213 GTEX-WFG7-1626-SM-4LVMF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Major depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.249 Nucleus lentiformis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.632 GTEX-XBED-0826-SM-47JYC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 ACKR2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0048403 CA7 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0059881 VRK1_knockout_64_GSE19329 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.76134 SLC7A9 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00521485 SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3428 GTEX-S32W-2326-SM-2XCAW GTEx Tissue Sample Gene Expression Profiles 1.0 0.861762 Perturb_9047_OE_PRRX1A_SRP168742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.09692 Cerebellum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.884 autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049961 Fatty acid elongase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.792 CRCGN017_MCF10A.TP53.M_24H:A17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.43571 cell projection part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.062534 GTEX-U3ZN-2026-SM-4DXUC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4036 GSE226452_1_v_2_imiquimod_mouse RummaGEO Drug Perturbation Signatures -1.0 null posteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61677 ca2+ Phosphosite Textmining Biological Term Annotations 1.0 null GSE128076_2_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-R55F-0011-R6A-SM-2TF4L GTEx Tissue Sample Gene Expression Profiles 1.0 1.79102 BRD-K51760683 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.72026 GTEX-SN8G-0926-SM-4DM5I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02351 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BLM LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00575912 TBC1D16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32665 cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072639 integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.1396 influenza DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.183248 cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.21627 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.8965 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.754537 Perturb_17635_KD_YTHDF2_SRP126652 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me2_RS411_n_603_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15587 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14991 Vascular Diseases CTD Gene-Disease Associations 1.0 1.17728 BRD-K73177528 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35186 hippocampus (hippocampal formation)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.827049 low tension glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.370737 arsenic trioxide_homo sapiens_gpl201_gse48441 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Postsynaptic density membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.663 GSE234289_4_v_2_rfx6_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X4XX-0011-R10B-SM-46MWO GTEx Tissue Sample Gene Expression Profiles 1.0 0.862667 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06649 CTBP2-25329375-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE164874_5_v_7_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-A21858158_-666_ASC_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hsa-miR-205 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.882404 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatonigral neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.394953 NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.1931 Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01411 Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1732_OE_Gata1_SRP082369 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.30861 abnormality of prenatal development or birth GWASdb SNP-Phenotype Associations 1.0 0.336877 GSE210101,GSE210114_6_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Neostriatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.711 microtubule organizing center attachment site COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.392001 BRD-K20987582 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31345 icSARA deltaORF6_54Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.80007 H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CRCGN015_MCF10A_48H:F02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5714 skeletalmuscle_d HPA Tissue Sample Gene Expression Profiles 1.0 1.26789 GRIA1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00614595 BRD-K79604175 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11579 ROCK_INHIBITION_GDS3944_464_mouse_Forebrain astrocytes - 24 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Hand grip strength GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5004-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 3.934 GSE228894_0_v_1_rnmt_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE147662_3_v_1_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null U2904 DepMap CRISPR Gene Dependency 1.0 3.50733 PMC11030494-media-2.xlsx-ST12-Supplementary_Table_12_Genes_identified_by_MAGMA_as_being_significantly_associated_with_the_internalizing_spectrum_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Mccoy TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.772 CRCGN016_MCF10A.TP53.M_24H:P16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.25319 Parietal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.524 BRD-K77272277 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33781 female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048673 PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null hypothalamus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null chr3_35524045_T_C_b38 GTEx eQTL 2025 1.0 3.86306 VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.89559 amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.837 BRD-A60245366_AS-601245_HS578T_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null IRF4-20064451-CD4+T-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NNMT LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00629089 BRD-K85615919 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01254 GSE102132_0_v_1_irf3_human RummaGEO Gene Perturbation Signatures -1.0 null PMC11801220-NIHMS2038999-supplement-15.xlsx-Exc-MAF-gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1581 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35065 GTEX-SSA3-0008-SM-47JWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC11030494-media-2.xlsx-ST12-Unnamed_9_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null E2A MotifMap Predicted Transcription Factor Targets 1.0 null hsa-miR-1915 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GSE189609_1_v_0_hax1_human RummaGEO Gene Perturbation Signatures -1.0 null B cell_Bone marrow_Human CellMarker Gene-Cell Type Associations 1.0 null cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044136 GTEX-X4XX-0011-R6B-SM-46MWP GTEx Tissue Sample Gene Expression Profiles 1.0 1.71102 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44O-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QEL4-1426-SM-447AC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K67578145_GDC-0879_MCF7_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE135439_0_v_1_pax5_human RummaGEO Gene Perturbation Signatures -1.0 null replication fork COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.367388 orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22964 PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null plasma membrane light-harvesting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.41923 alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.697808 uterine cervix TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06912 SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26776 GSE145476_2_v_0_hopx_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QDVJ-0008-SM-48U2E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GO-06A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCNK15 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00336619 Perturb_15293_OE_Fos_SRP304877 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.49556 16527891-Table1 GeneSigDB Published Gene Signatures 1.0 null BRD-K56055036 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14622 BRD-K60337516 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04428 GTEX-Q2AG-0011-R11A-SM-2HMKZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.07941 GTEX-SIU8-0008-SM-4BRUC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-XXEK-0008-SM-4BRW7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CACNG6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60152 GTEX-Q2AG-0011-R3A-SM-2HMJ9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.896805 clonorchiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.637495 Adrenocortical carcinoma_ACC_TCGA-OR-A5JZ-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-ensembl_gene_id_BCL6 Rummagene Transcription Factor Associations 2026 1.0 null STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null brain_a HPA Tissue Sample Gene Expression Profiles 1.0 2.00842 Perturb_2893_KO_Nfia_SRP077282 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.0714 Specific developmental disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.908 NME3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00498081 muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.670064 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0714 RUNX1-17652178-JURKAT-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null pralidoxim LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5107 GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 1.05568 PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8 Rummagene Transcription Factor Associations 2026 1.0 null SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE100464,GSE100465_1_v_3_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02479 Perturb_9467_KO_Dbx1_SRP353027 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.70794 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-T2IS-1926-SM-4DM74 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC8803621-mmc5.xlsx-54JIB-04genes_w_GATA4_motif-GATA4_Q3_GATA4 Rummagene Transcription Factor Associations 2026 1.0 null PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null GSE210101,GSE210114_5_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.463149 PMC4154952__F5 PFOCR Pathway Figure Associations 2024 1.0 null Forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-WL46-0011-R7A-SM-3LK7X GTEx Tissue Sample Gene Expression Profiles 1.0 1.73927 GTEX-XUYS-0226-SM-47JX1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07571 BRD-K25768791 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43641 GSE202434,GSE202438_7_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null DMS-114 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XBED-0226-SM-47JY8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Perturb_15360_KO_Tfap4_SRP212619 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.24933 HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.82634 BRD-K85909950 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34155 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17776 brain Phosphosite Textmining Biological Term Annotations 1.0 null BRD-K95709431 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13208 CRCGN017_MCF10A.WT.HP_24H:N23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.31395 striatum (corpus striatum) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18986 MedullaOblongata BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.49496 NMCG1 CCLE Cell Line Gene Expression Profiles -1.0 -1.47252 Cerebral peduncle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.672 CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CRCGN011_HEPG2_24H:K09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.3581 BRD-K57226763 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1196 SIRT1_KO_GDS4895_410_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE168807_0_v_7_dnmt3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCT15 BioGPS Cell Line Gene Expression Profiles -1.0 -0.901906 EDN1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00349825 r7 part of the nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22748 ITGA1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00659821 thymus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 RUNX1-22343733-PBMC-HUMAN-BONEMARROW ChEA Transcription Factor Targets 2022 1.0 null PBX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66666 BRD-K41141507 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.61323 Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JC-2426-SM-3NMDB GTEx Tissue Sample Gene Expression Profiles 1.0 0.899976 hsa-miR-4499 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Prestwick-860-4618 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HNF3A MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K45421483 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23776 GSE174498,GSE174500_2_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null Hyperplasia CTD Gene-Disease Associations 1.0 1.56459 SCH DepMap CRISPR Gene Dependency 1.0 9.65277 Excretory gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 accumbens nucleus, core domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18434 FOXO1-25302145-T-LYMPHOCYTE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null head of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.81828 layer 2 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16543 DMS454 CCLE Cell Line Gene CNV Profiles -1.0 -2.3468 BRD-K23280067 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83681 Thymus-fast muscle cell Tabula Sapiens Gene-Cell Associations 1.0 4.176 capsular epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.230382 DAUDI COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null hindlimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.610943 GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.994975 BRD-K26314798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42341 A_CA_04_2009_7dayMOI-10^6_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.73175 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE195559_8_v_5_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_4195_KD_Pqbp1_SRP018775 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.2762 GSE138001_2_v_3_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26562 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2477 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5987 GTEX-WL46-0011-R5A-SM-3LK6V GTEx Tissue Sample Gene Expression Profiles 1.0 1.7127 BRD-K47962810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.85903 GSE139911_0_v_4_dnmt3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 PMC5771393-ACEL-17-na-s003.xlsx-FOXO1_Correlation_Neg-HUGO_FOXO1 Rummagene Transcription Factor Associations 2026 1.0 null CRCGN015_MCF10A.TP53.M_24H:B21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.4249 GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles 1.0 0.830692 GSE222758_0_v_2_clofazimine_human RummaGEO Drug Perturbation Signatures -1.0 null ZKSCAN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2518 hsa-miR-3150a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE135350_2_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.412011 GSE231720,GSE231724_2_v_1_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE147662_0_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null BRD-K69453266 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.82295 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9944 Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8498_OE_Sox9_SRP375106 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.34823 keratoconjunctivitis sicca DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.161716 GSE135350_3_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE126127_5_v_3_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE210580_0_v_12_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X585-3026-SM-46MWF GTEx Tissue Sample Gene Expression Profiles 1.0 0.941129 MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null GSE236486_1_v_0_arnt_human RummaGEO Gene Perturbation Signatures -1.0 null type iii protein secretion system complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.590973 GTEX-XOTO-0011-R11B-SM-4B64O GTEx Tissue Sample Gene Expression Profiles 1.0 1.09655 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-WVLH-0011-R7A-SM-3MJFB GTEx Tissue Sample Gene Expression Profiles 1.0 0.991311 CALM3 Hub Proteins Protein-Protein Interactions 1.0 null hsa-miR-3146 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 caudate nucleus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.842397 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null Human - Fetal Development - L2 - Heart-SATB2_LRRC7 positive cells HuBMAP Azimuth Cell Type Annotations 1.0 null Hindbrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.299 Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus LOCATE Predicted Protein Localization Annotations 1.0 null POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4584 MZ1-PC COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QVJO-0011-R6A-SM-2S1QN GTEx Tissue Sample Gene Expression Profiles 1.0 2.13026 GTEX-UTHO-0008-SM-4JBID GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 quadriceps TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.183177 JM1 CCLE Cell Line Gene Expression Profiles 1.0 1.60825 GSE182680,GSE182683_7_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-P4QS-0926-SM-48TBS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-767-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.299601 cell wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.191135 GSE116810_5_v_4_selinexor_human RummaGEO Drug Perturbation Signatures -1.0 null cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.75495 BRD-K69423881 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13674 MOLT13 CCLE Cell Line Gene Expression Profiles 1.0 1.45597 plasma membrane-derived chromatophore membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.10817 hsa-miR-3617 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Acute biphenotypic leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.11 periventricular stratum of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04398 GTEX-XV7Q-0326-SM-4BRVM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-Q2AI-0826-SM-48TZO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34484 forestomach TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.42191 periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05507 HuCCT1 GDSC Cell Line Gene Expression Profiles -1.0 -1.56176 lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.482428 BRD-K49552510 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16603 GTEX-Q2AG-0011-R4A-SM-2HMKA GTEx Tissue Sample Gene Expression Profiles 1.0 0.853388 other organism part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.13837 Thyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.875183 enterocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.31332 GSE94849_7_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 GTEX-T2IS-0011-R3A-SM-32QPB GTEx Tissue Sample Gene Expression Profiles 1.0 0.993375 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57628 KPNYN DepMap CRISPR Gene Dependency 1.0 2.27269 PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A Rummagene Transcription Factor Associations 2026 1.0 null myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.051999 hematopoietic cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE132948,GSE132949_0_v_1_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Intracellular organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.502 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Perturb_13059_Mut|OE_Sik3E13_SRP334442 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.65841 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.50311 GSE219195_0_v_5_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_15897_KD_GLI1_SRP241956 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.203 GSE145311_0_v_2_glutathione_mouse RummaGEO Drug Perturbation Signatures -1.0 null fluoxetine_mus musculus_gpl1261 _gds2803 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.454 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08356 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.39851 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5113-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Abdominal Pain CTD Gene-Disease Associations 1.0 1.23106 GTEX-S4Q7-0003-SM-3NM8M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-QV31-0008-SM-447AT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE128634,GSE128636_1_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null endometrium HPA Tissue Gene Expression Profiles -1.0 -0.931182 NKX3-2 JASPAR Predicted Transcription Factor Targets 1.0 null medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09824 seedling TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.720755 GSE174498,GSE174500_0_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null bronchoalveolar system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072642 CRCGN016_MCF10A.TP53.M_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.9728 medial parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17068 Hepatitis CTD Gene-Disease Associations 1.0 1.04831 kidney cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.983057 GTEX-XXEK-1426-SM-4BRW1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.67984 BRD-K50413145 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26066 Perturb_16840_KO_Bcl11b_SRP340294 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 hsa-miR-3973 TargetScan Predicted Conserved microRNA Targets 1.0 0.404082 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.835 GTEX-U3ZN-2226-SM-3DB88 GTEx Tissue Sample Gene Expression Profiles 1.0 0.910224 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4970-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6258 GTEX-XUJ4-1026-SM-4BOPB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Acute Kidney Injury CTD Gene-Disease Associations 1.0 1.9742 GSE198794_2_v_1_usp18_human RummaGEO Gene Perturbation Signatures 1.0 null alpha-beta T cell receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.536 BRD-K27610371 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53814 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null host intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.330966 MDA MB435 BioGPS Cell Line Gene Expression Profiles 1.0 1.38628 ABLIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01197 REST-18959480-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE122509,GSE122513_3_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-3646 TargetScan Predicted Conserved microRNA Targets 1.0 0.111118 typhoid fever DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.206248 BRD-K16717067 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20641 PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_I-Unnamed_1_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55C-0726-SM-48FCN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE142019,GSE142021_10_v_3_ythdf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K14399036 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23777 Autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.467 GTEX-TSE9-1226-SM-4DXTM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Human - Bone Marrow - L1 - Hematopoeitic stem and progenitor cell HuBMAP Azimuth Cell Type Annotations 1.0 null 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.39372 UBE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39395 spinal column TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.377245 BRD-K55584718 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42372 ZNF37A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23222 GSE182680,GSE182683_5_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042871 TP53INP2_OE_GDS5054_387_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-U3ZM-1226-SM-3DB9G GTEx Tissue Sample Gene Expression Profiles 1.0 0.8741 496100608_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.32987 Copula pyramidis, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87781 SPI1 ChEA Transcription Factor Targets 1.0 null GSE182680,GSE182683_10_v_8_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-SUCS-0526-SM-4DM56 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null MOLT4 CCLE Cell Line Gene Expression Profiles 1.0 1.47252 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.854349 Perturb_13570_KD_Islr_SRP160431 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 muscle GTEx Tissue Gene Expression Profiles 1.0 1.23127 superior vena cava TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.227186 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57628 HLA-DQA2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00556176 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PWCY-1726-SM-48TD3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PF382 CCLE Cell Line Gene Expression Profiles 1.0 2.04658 Abnormalities, Drug-Induced CTD Gene-Disease Associations 1.0 1.62106 TE-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T5JW-1526-SM-4DM5E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE94011_2_v_1_pias3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WEY5-1926-SM-3GIL8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-4672 TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 GTEX-T5JC-0011-R5A-SM-32PLK GTEx Tissue Sample Gene Expression Profiles 1.0 1.76892 Perturb_17326_KO_Dis3_SRP328540 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.08479 GTEX-R55D-0008-SM-48FEV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 nucleus subceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.836473 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6513 GSE116810_2_v_0_selinexor_human RummaGEO Drug Perturbation Signatures 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.93206 leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.72322 BRD-K17060750 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61999 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.19273 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.059 Blood cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Nucleus preopticus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.609 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.89672 17177833-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null lymphoid tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.595255 hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20916 BRD-K89108431 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26996 GTEX-TMMY-1926-SM-4DXUU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28564 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.04828 GTEX-T2IS-3026-SM-32QPM GTEx Tissue Sample Gene Expression Profiles 1.0 1.00933 GTEX-WEY5-0726-SM-4LMID GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles 1.0 1.07261 GSE218060_1_v_3_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null transporter complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.074585 GTEX-R55E-0011-R5A-SM-2TC5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.65375 GTEX-WL46-0011-R2A-SM-3LK6O GTEx Tissue Sample Gene Expression Profiles 1.0 1.59836 GTEX-Q2AH-0826-SM-48TZN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81S-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFG7-1126-SM-4LMK3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-U3ZN-1626-SM-4DXTZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 1.03937 ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70571 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.430505 HSC3 DepMap CRISPR Gene Dependency 1.0 2.19992 host cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.672243 gastric cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.122689 JHOM1 DepMap CRISPR Gene Dependency 1.0 2.63598 Human - Motor Cortex - Cluster - SST+ DEFB108B+ Layer 1 GABAergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null GTEX-S341-0826-SM-4AD73 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Periodontal Inflammation DisGeNET Gene-Disease Associations 1.0 null Perturb_14006_KO_Perk_SRP370072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.7868 GSE229468,GSE229471_0_v_3_znf587_human RummaGEO Gene Perturbation Signatures -1.0 null GSE151612_0_v_8_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00523 mantle zone of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10655 CRYBB1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00495684 BRD-K81473043_-666_PL21_6.0_h_0.35_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_2270_KO_lincBrn1b_SRP028547 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null GTEX-X585-0011-R10A-SM-46MUY GTEx Tissue Sample Gene Expression Profiles 1.0 0.978349 GSE145915_0_v_1_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE160083,GSE160084_1_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null organelle subcompartment COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.347967 Perturb_11952_OE_MYC_SRP355809 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR Rummagene Transcription Factor Associations 2026 1.0 null SUN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92503 SUZ12 ChEA Transcription Factor Targets 1.0 null ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.2185 BRD-K40145790 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31419 BRD-A19037878_trichostatin A_HCC15_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K14476597 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20846 glutamyl-tRNA(Gln) amidotransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.797 PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1 Rummagene Transcription Factor Associations 2026 1.0 null layer 2 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19274 gastric cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.117104 GSE115363_1_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null TSSK1B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00547631 GSE169152_3_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 GSE101239_5_v_0_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.55756 HUASMC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.922 POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K49669041_HY-11005_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.789 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null urinary system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.888221 hsa-miR-497 TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.07 substance abuse DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.215314 GTEX-R55C-0826-SM-48FCL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-4775 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 CRCGN016_MCF10A.WT.HP_24H:P22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.81185 GSE222758_0_v_1_clofazimine_human RummaGEO Drug Perturbation Signatures -1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6269 BRD-K99749624_S1003_VCAP_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Primary visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91645 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XYKS-1526-SM-4BRUP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055763 GTEX-XOTO-0011-R5A-SM-4B657 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38585 hsa-miR-4291 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 layer 4 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12574 vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.31464 BRD-K48325920 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22399 PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC Rummagene Transcription Factor Associations 2026 1.0 null Bipolar disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.198 r7 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31406 MUTZ5 CCLE Cell Line Gene CNV Profiles -1.0 -1.7639 Microglial cell_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.80937 GSE69869_0_v_1_panobinostat_mouse RummaGEO Drug Perturbation Signatures -1.0 null BRD-K34747076 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40983 DND41 CCLE Cell Line Gene Expression Profiles 1.0 1.52065 Anemia CTD Gene-Disease Associations 1.0 1.10769 BRD-K07384081 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23732 Perturb_16403_KO_Grpel1_SRP363877 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.98255 GTEX-PX3G-1026-SM-48TZW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Posterior amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.618 lymphoblastoid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062534 Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null APEX1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00566218 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null BRD-K50472386 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34236 Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K37931645 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35657 GSE169152_3_v_4_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH1155 CCLE Cell Line Gene Expression Profiles 1.0 1.43123 GSE141328_3_v_2_rock2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ganglion TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-T5JW-0926-SM-4DM5K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 medial temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.240216 EB-3 GDSC Cell Line Gene Expression Profiles 1.0 1.85928 Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.80632 BRD-K16919185 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09964 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12305 GTEX-N7MT-0011-R5a-SM-2I3G6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.58074 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NN-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11625982-AJH-100-10-s001.pdf-60-POU2F2_POU2F2 Rummagene Transcription Factor Associations 2026 1.0 null GSE111061_1_v_0_tofacitinib_human RummaGEO Drug Perturbation Signatures -1.0 null substance dependence GWASdb SNP-Disease Associations 1.0 0.312437 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.778155 BRD-K66551929 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39529 hsa-miR-4659a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GTEX-V955-0126-SM-4JBH5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CRCGN016_MCF10A.TP53.M_24H:O07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.25962 BRD-K31526203 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29148 RAGE_knockout_269_GSE22873 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.62118 Basal ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2359 GTEX-WHSE-0011-R7A-SM-3P5YZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.81236 Lymphoid tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 3.934 dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1066 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70144 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.09695 GTEX-XUW1-0008-SM-4BOQH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Nervous System Diseases CTD Gene-Disease Associations 1.0 1.20913 hsa-miR-451b TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.688576 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null RSC1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86179 GSE206516,GSE206518_0_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate (interpositus) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0776 6-benzylaminopurine-2351 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GSE210580_4_v_12_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles 1.0 0.924813 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.161989 EZR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76977 PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S12-ZNF384_DiffExprGene-Unnamed_1_ZNF384 Rummagene Transcription Factor Associations 2026 1.0 null KLF2_01_226 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59598 GSE156115_2_v_1_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Copula pyramidis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80382 GTEX-QLQ7-0926-SM-447BC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 VZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.945007 Borjeson-Forssman-Lehmann syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.133 CRCGN016_MCF10A.TP53.M_24H:O19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.80447 GTEX-WWYW-0011-R6A-SM-3NB3G GTEx Tissue Sample Gene Expression Profiles 1.0 2.14688 GTEX-S7SE-0011-R10A-SM-2XCDF GTEx Tissue Sample Gene Expression Profiles 1.0 0.928854 TP53INP2_OE_GDS5054_385_mouse_Muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null tooth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.22336 BRD-K88195243 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36216 KRAS.KIDNEY_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null GTEX-WZTO-2826-SM-3NM8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.0886 BRD-K52796804 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0741 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T2IS-2926-SM-32QPO GTEx Tissue Sample Gene Expression Profiles 1.0 1.09965 BRD-K54506283 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07847 GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.98338 chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.177724 receptors Phosphosite Textmining Biological Term Annotations 1.0 null Nucleus accumbens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.369 CRCGN016_MCF10A.TP53.M_24H:D19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.35178 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 1.0327 nucleus accumbens TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.478534 alpha dna polymerase:primase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.232386 Fetal Heart Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.81735 HHV8_72Hour-BEC_20080955_GSE16354 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -3.04303 GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles 1.0 0.944245 GSE128634,GSE128636_4_v_5_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4461 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GSE201239_3_v_4_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null immature cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.287447 Oligospermia CTD Gene-Disease Associations 1.0 1.29225 GSE48812_9_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WFG8-0126-SM-4LVMH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05904 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NL3H-0011-R10A-SM-2I3E9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.890591 PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null BRD-K82968105 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.88734 SKNAS CCLE Cell Line Gene CNV Profiles -1.0 -1.49439 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78632 olanzapine_rattus norvegicus_gpl1355_gse2547 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null primary motor cortex (area M1, area 4)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.919184 bubonic plague DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.610838 parasitic infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.201962 LMO2 ChEA Transcription Factor Targets 1.0 null peripheral blood lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.230656 GSE214382,GSE214383_6_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null SPECC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5405 H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FCER1G LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00485587 H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphatic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.073 root TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078303 pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.85351 BRD-K44777226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00924 CRCGN017_MCF10A.WT.HP_24H:O04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.01469 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.877553 gigantocellular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00994 dopamine Phosphosite Textmining Biological Term Annotations 1.0 null CRCGN008_HEPG2_24H:K09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2075 DHRS4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0054342 GTEX-X5EB-0008-SM-46MU3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 striatum_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19176 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_0Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.59198 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.58285 BRD-K76067434 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25685 BRD-K44648112 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77562 Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE182680,GSE182683_0_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38104 CD56+_NKCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.24952 GSE120612_7_v_3_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null Avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.475 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WZTO-0011-R7B-SM-4E3IS GTEx Tissue Sample Gene Expression Profiles 1.0 1.50984 MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7482 BHLHE40 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00384391 GTEX-WYBS-0926-SM-3NM94 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE115363_2_v_4_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null cattle Phosphosite Textmining Biological Term Annotations 1.0 null GTEX-QVJO-0008-SM-447AU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3924-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.898972 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02439 NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null ALDH7A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01591 disease GWASdb SNP-Disease Associations 1.0 0.036055 NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.971505 BRD-K56107062 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00134 GTEX-RU72-0011-R5A-SM-2TF6U GTEx Tissue Sample Gene Expression Profiles 1.0 1.66739 GTEX-XUZC-0926-SM-4BOQF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K58498516 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03524 Perturb_10626_KO_Poldip2_SRP302743 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 JMSU1 CCLE Cell Line Gene Expression Profiles -1.0 -1.59954 hsa-miR-449c TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 human granulocytic anaplasmosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.460883 GTEX-NL3H-0011-R6a-SM-2I3G8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.01164 mRNA_T_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null SP100_01_82 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.92235 GTEX-OXRP-2426-SM-2S1NR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K91645615 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42162 BRD-K35964249 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34127 GTEX-R45C-0008-SM-48FF2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K00551139 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48507 ALDH3B1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00629396 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8125 Perturb_5830_KO_Ddx41_SRP325771 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE120336_1_v_2_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null DBIRD complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.623 hsa-miR-2682 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GSE195786_0_v_2_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881054 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.93229 systemic mycosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.060738 PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null SMARCA4 ChEA Transcription Factor Targets 1.0 null GTEX-N7MS-0011-R10A-SM-2HMJK GTEx Tissue Sample Gene Expression Profiles 1.0 0.880003 plastid part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.252927 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.832302 GTEX-WFON-0326-SM-3GIKX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CRCGN017_MCF10A.WT.HP_24H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.8809 SLC7A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30346 posteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3282 GTEX-U3ZN-0726-SM-4DXT5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K05786443 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87092 ZNF233 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91112 Gli2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.7681 CRCGN016_MCF10A.WT.HP_24H:O24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.03114 C13orf42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42391 Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 1.13552 MEAF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.299 hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03363 intermediate stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00882 NALM19 CCLE Cell Line Gene Expression Profiles 1.0 2.40869 BRD-K08811598 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0748 r10 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00176 Human - Tonsil - L2 - preB HuBMAP Azimuth Cell Type Annotations 1.0 null GSE160077,GSE160084_3_v_0_bin1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TUBD1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00665696 HPSE LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00709511 GTEX-TMMY-0126-SM-4DXTP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE213588_8_v_5_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null Lymphatic system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 PPFIA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42905 GSE128634,GSE128636_2_v_0_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5968 VZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09551 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33091 GSE96777,GSE96778_3_v_2_zbtb4_human RummaGEO Gene Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mouth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.11154 layer 3 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26074 human monocytic ehrlichiosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.673917 gill TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.323874 GTEX-NL4W-0011-R6a-SM-2I3GA GTEx Tissue Sample Gene Expression Profiles 1.0 1.61466 cerebral lobe TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null JURKAT CCLE Cell Line Gene Expression Profiles 1.0 1.79783 Perturb_3555_KD_AURKB_SRP230801 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PEO4 DepMap CRISPR Gene Dependency 1.0 6.34452 GSE218060_2_v_6_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.901217 HNF4 MotifMap Predicted Transcription Factor Targets 1.0 null GSE132948,GSE132949_2_v_3_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BE-13 GDSC Cell Line Gene Expression Profiles 1.0 1.5546 GSE218060_5_v_0_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K42385001 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21422 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41686 LGALS9 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00493664 KYAE1 DepMap CRISPR Gene Dependency 1.0 4.68607 carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.392257 GSE234637_1_v_0_ikzf1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PWN1-2026-SM-48TD9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CRCGN015_HEPG2_48H:H04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.04809 GSE142684_4_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null renal corpuscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.166825 COLO684 DepMap CRISPR Gene Dependency 1.0 3.12633 GTEX-V955-2026-SM-3GAFA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 TMEM119 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00596943 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null MBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96336 GTEX-XLM4-0011-R6A-SM-4AT4B GTEx Tissue Sample Gene Expression Profiles 1.0 2.01839 KLF15_KO_GDS4780_419_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE94849_1_v_4_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null interstitial GeneRIF Biological Term Annotations 1.0 null striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.952711 CRCGN008_HEPG2_24H:M17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.13795 GTEX-VUSG-2426-SM-4KKZG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11947 TINAGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92033 testosterone_rattus norvegicus_gpl1355_gse15243 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE119498_2_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null CCAAT-binding factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.157 mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.841874 BRD-K30022119 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0147 GSE66014_0_v_1_perhexiline_human RummaGEO Drug Perturbation Signatures 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.46898 GSE81803,GSE81912_3_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K01853388 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30271 GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 0.885367 GTEX-QEG4-0226-SM-2S1PY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 b875 antenna complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.41867 Myeloid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.442418 GTEX-WL46-0011-R11A-SM-3MJFT GTEx Tissue Sample Gene Expression Profiles 1.0 1.11944 GTEX-WL46-0011-R3A-SM-3TW8E GTEx Tissue Sample Gene Expression Profiles 1.0 0.854629 Caudate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.689 PMC3432194__F2 PFOCR Pathway Figure Associations 2024 1.0 null GSE160083,GSE160084_2_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Temporal lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Translation initiation complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.917 IFNA7 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00484569 Entorhinal cortical thickness GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.722185 GTEX-T6MN-0011-R5A-SM-32QPD GTEx Tissue Sample Gene Expression Profiles 1.0 2.24593 GTEX-POMQ-0126-SM-48TD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29125 Retrosplenial area, lateral agranular part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02289 GSE182680,GSE182683_0_v_8_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null medial (fastigial) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80743 JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.48147 cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.677395 forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null polymorph layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11537 SLC19A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08714 GSE169152_5_v_7_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.6889 GSE129370_2_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XMK1-0226-SM-4B65D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 ribavirin_homo sapiens_gpl570_gds4391 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-A47166394 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.0988 GTEX-SUCS-1426-SM-4DM5W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.79413 GSE150055_0_v_1_melphalan_human RummaGEO Drug Perturbation Signatures -1.0 null GSE116810_2_v_1_selinexor_human RummaGEO Drug Perturbation Signatures 1.0 null PIEZO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40453 Adult Acute Lymphocytic Leukemia DisGeNET Gene-Disease Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4765-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-2926-SM-3LK82 GTEx Tissue Sample Gene Expression Profiles 1.0 0.86355 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.057255 mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null LGALS1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00366844 GTEX-N7MS-0011-R3a-SM-33HC6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.953928 Opioid-Related Disorders CTD Gene-Disease Associations 1.0 1.07482 CRCGN015_MCF10A.WT.HP_24H:H09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.09988 PMC9895410-Table_1.xlsx-Neuroendocrine_regulation_genes-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null 15374961-TableS2 GeneSigDB Published Gene Signatures 1.0 null brain ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.267446 mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-WOFL-0626-SM-3MJG3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.874876 GTEX-P44H-0011-R4A-SM-2XCEW GTEx Tissue Sample Gene Expression Profiles 1.0 0.856466 BRD-K11419664 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42479 hsa-miR-888 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4317_KO_Fmn2_SRP109283 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.71597 GTEX-QDVN-1226-SM-48TZ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Perturb_600_KO_Runx1_SRP267560 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.5499 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 supraoptic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.97213 GTEX-R55G-0008-SM-48FEX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-QDT8-0011-R6A-SM-32PKI GTEx Tissue Sample Gene Expression Profiles 1.0 1.13454 ESS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.732191 mice-transgenic Phosphosite Textmining Biological Term Annotations 1.0 null hsa-miR-4456 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 ciliary part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.058379 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.202946 adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.388909 Nausea CTD Gene-Disease Associations 1.0 1.23488 VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4091 BRD-K72424071 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44087 Bradycardia CTD Gene-Disease Associations 1.0 1.10907 NCI-H2030 COSMIC Cell Line Gene Mutation Profiles 1.0 null gestational diabetes GWASdb SNP-Disease Associations 1.0 0.735751 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE169152_5_v_2_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null TE-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QVUS-0011-R6A-SM-3GACX GTEx Tissue Sample Gene Expression Profiles 1.0 1.41045 Perturb_13531_KO_Lmna_SRP012097 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.7492 GTEX-QCQG-0526-SM-48U2A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-OXRN-0126-SM-48TDM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GATA3-21867929-CD8-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GATA1-19941827-MEL-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKNFI DepMap CRISPR Gene Dependency 1.0 2.87782 BRD-K39131701 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.121 abnormal channel response MPO Gene-Phenotype Associations 1.0 null GTEX-XLM4-2926-SM-4AT59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01528 GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.91439 BRD-K31372389 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13652 septostriatal transition area (accumbens) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02512 hsa-miR-1323 TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 MAPK12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61914 pleomorphic liposarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.635528 GSE111660_1_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary motor-sensory cortex (samples)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.894815 PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5 Rummagene Transcription Factor Associations 2026 1.0 null KASUMI2 CCLE Cell Line Gene Expression Profiles 1.0 1.39636 BRD-K64553072 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3333 lymphoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061339 Syndromic intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.075 CAMA-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.644 GSE207611,GSE207612_3_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Immune system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 TMEM41B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77594 CCND1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0101143 GSE206516,GSE206518_6_v_4_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08611 BRD-K99517495 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03482 BRD-K41690760 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49225 GTEX-WVLH-0011-R11A-SM-3MJFO GTEx Tissue Sample Gene Expression Profiles 1.0 1.11198 Specific granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.634 GSE119498_0_v_5_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null CKM complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.723 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18647 HCN2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00824609 GTEX-WI4N-0626-SM-3TW8Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 HUPT4 CCLE Cell Line Gene CNV Profiles 1.0 1.89341 Edema CTD Gene-Disease Associations 1.0 1.67611 TEAD4-22529382-TROPHECTODERM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PIK3CA_mutant_27_GDS4053 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.15311 GSE125025_2_v_3_lyl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.514924 Hypertension CTD Gene-Disease Associations 1.0 1.36533 GTEX-QLQW-0226-SM-447BJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 protein binding GO Molecular Function Annotations 2015 1.0 null GTEX-S7SE-0011-R11A-SM-2XCDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.08839 cell culture TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.627081 POU3F2 ChEA Transcription Factor Targets 1.0 null SKOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93502 SLVL DepMap CRISPR Gene Dependency 1.0 2.70139 ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6783 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 superficial stratum of OCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02289 BRD-K49529874 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4516 GSE116810_5_v_1_selinexor_human RummaGEO Drug Perturbation Signatures -1.0 null GSE210101,GSE210114_1_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0981 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069662 primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.867119 PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K59484021 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17206 GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.21388 molt4 HPA Cell Line Gene Expression Profiles 1.0 0.909401 PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null GSE164874_5_v_4_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null putamen, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.83379 A375 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2722 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.827473 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.06735 cytosolic proteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.1426 CHMP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5238 Well Differentiated Oligodendroglioma DisGeNET Gene-Disease Associations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE120336_0_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0386 hsa-miR-1263 TargetScan Predicted Conserved microRNA Targets 1.0 0.257113 GSE182680,GSE182683_5_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-4765 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 musculoskeletal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047026 17429429-Table1 GeneSigDB Published Gene Signatures 1.0 null bronchoalveolar lavage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.586828 Perturb_17767_KO_Prdm16_SRP238935 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.72584 GSE218580_1_v_5_fentanyl_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-PX3G-2426-SM-48TZZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 NO10 DepMap CRISPR Gene Dependency 1.0 2.4575 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PFKFB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43935 GTEX-QCQG-1426-SM-48U22 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 VM-CUB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Visual cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.049 ERCC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96601 Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.12797 histoplasmosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.277584 Waist-hip index GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.00969 cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null T-REx 293 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.937 GSE160817_2_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null pka-mediated Phosphosite Textmining Biological Term Annotations 1.0 null MM127 DepMap CRISPR Gene Dependency 1.0 4.4934 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0455 parasitic helminthiasis infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.099293 SYCE1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16282 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NEK5 Kinase Library Serine Threonine Kinome Atlas 1.0 null olanzapine_rattus norvegicus_gpl1355_gds2608 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE94849_6_v_4_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7272 Perturb_1745_KO_Tet2/Tet3_SRP063091 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.196779 LAMTOR3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00625105 BRD-K04791118 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07095 GTEX-Q2AI-0008-SM-48U2H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 1.00733 Whole Blood GTEx Tissue Gene Expression Profiles 2023 1.0 5.42159 hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.125975 ASCL2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00452271 GSE126345_2_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE69244_1_v_0_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29E-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH28 CCLE Cell Line Gene CNV Profiles 1.0 1.51661 GTEX-T2IS-2026-SM-4DM6W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 keratocyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.8026 GSE234289_5_v_2_rfx6_human RummaGEO Gene Perturbation Signatures -1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null mononuclear phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.08161 LC4-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17875 BRD-K78288885 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.0234 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.84102 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.96285 GTEX-NL3H-0011-R5a-SM-2I3GB GTEx Tissue Sample Gene Expression Profiles 1.0 1.13783 corpus striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.768197 BRD-K98062520 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07739 biological_process GO Biological Process Annotations 2015 1.0 null primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.07498 vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078468 GSE124375_10_v_9_chd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE101239_5_v_6_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null MAP3K2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00642979 adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063009 GTEX-N7MS-2526-SM-2D7W3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.998829 GSE231891_3_v_4_cdk8_human RummaGEO Gene Perturbation Signatures 1.0 null PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null PRKACA KEA Substrates of Kinases 1.0 null H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RNOR-0011-R7A-SM-2TF4V GTEx Tissue Sample Gene Expression Profiles 1.0 1.98073 SMPDL3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8931 GSE205163,GSE205164_2_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R4-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ethanol_mus musculus_gpl6105 _gds3703 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K80225716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06862 BRD-K31393518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23037 Parabrachial nucleus, medial division, medial medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00764 ethanol_mus musculus_gpl6105_gds3703 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-NPJ8-0011-R10A-SM-2YUMO GTEx Tissue Sample Gene Expression Profiles 1.0 0.866082 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE218060_7_v_3_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null chloroplast thylakoid membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.612048 Bgm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.885 Neostriatum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.016 CRCGN011_HEPG2_24H:N02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.94065 DOK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928873 Tal-1beta:ITF-2 MotifMap Predicted Transcription Factor Targets 1.0 null hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07405 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 esophagus_5a HPA Tissue Sample Gene Expression Profiles 1.0 0.955727 Posterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66924 cartilage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.415434 ISHIKAWAHERAKLIO02ER DepMap CRISPR Gene Dependency 1.0 2.90657 small intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.082674 Craniofacial Abnormalities CTD Gene-Disease Associations 1.0 1.05015 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05979 motoneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.836575 GTEX-XUZC-1726-SM-4BRWS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Blood Coagulation Disorders CTD Gene-Disease Associations 1.0 1.01025 cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.368888 bladder GTEx Tissue Gene Expression Profiles -1.0 -1.07357 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02332 GSE128634,GSE128636_2_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.60454 Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13896 Anterior commissure TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.907 T-cell chronic lymphocytic leukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE94849_1_v_2_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0965 carcass TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.488276 GSE174498,GSE174500_2_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-P4PQ-0126-SM-2S1NM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-QMR6-0011-R5A-SM-32PKT GTEx Tissue Sample Gene Expression Profiles 1.0 1.36013 NHLRC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20928 hsa-miR-1280 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 photosystem ii COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.97345 hsa-miR-502-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 striatum_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.48052 MDAPCA2B CCLE Cell Line Gene Expression Profiles -1.0 -2.35922 DIS3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50492 GTEX-PWCY-0226-SM-48TD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null PLA2G15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14335 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phosphatase Phosphosite Textmining Biological Term Annotations 1.0 null Central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2 Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.50652 PTPN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64978 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5659 chemdependency GAD High Level Gene-Disease Associations 1.0 0.293278 mammalian phenotype MPO Gene-Phenotype Associations 1.0 null PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAF-gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null lateral ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33744 GSE160817_5_v_6_slamf6_human RummaGEO Gene Perturbation Signatures 1.0 null Urinary tract TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.7756 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null amygdala TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE151782_2_v_7_aim2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE208254_3_v_1_irf8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE152699,GSE152723_3_v_2_vemurafenib_human RummaGEO Drug Perturbation Signatures -1.0 null thorax TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Caudoputamen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19572 dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.157089 SV2A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0064372 GTEX-U3ZM-0826-SM-4DXU6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.999679 GSE133516_0_v_3_kat7_human RummaGEO Gene Perturbation Signatures 1.0 null SOX4 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-Q734-1626-SM-48U1B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 corticoid layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13624 lipomatous cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.120265 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_DN4_ChIP-seq_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.888398 host cell nuclear part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.330966 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null 624 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.814 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28088 caudate putamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.407832 GSE111660_1_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0267 NCIH2029 CCLE Cell Line Gene CNV Profiles 1.0 1.38441 Urinary system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CAPAN1 CCLE Cell Line Gene CNV Profiles 1.0 2.15263 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8196-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null putamen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24837 DGKI LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00443883 d2 Phosphosite Textmining Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-99-7458-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU1197 CCLE Cell Line Gene Expression Profiles -1.0 -2.01049 respiratory chain complex iii COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.470406 LN464 CCLE Cell Line Gene Expression Profiles -1.0 -2.61636 IRF8-22096565-A-GC-B-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-0326-SM-3K2B1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CRCGN008_HEPG2_24H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.4653 ARIH2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0038365 avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.22415 pre-T cell receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.67 Piriform area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21552 cell envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.587618 skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles 1.0 1.10838 PMC9075502-crc-21-0022-s07.xlsx-WT_IgM_vs_KD_IgM-Unnamed_0_AR Rummagene Transcription Factor Associations 2026 1.0 null cyclic-amp-dependent-protein-kinases Phosphosite Textmining Biological Term Annotations 1.0 null PEER CCLE Cell Line Gene Expression Profiles 1.0 1.76889 GTEX-PVOW-0011-R3A-SM-32PKX GTEx Tissue Sample Gene Expression Profiles 1.0 0.971603 globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.156837 nadolol-3020 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-NL3H-0011-R7a-SM-2I3G5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.859021 striatum Phosphosite Textmining Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 0.922166 Pancreatitis CTD Gene-Disease Associations 1.0 1.02933 Perturb_15613_Mut_Dmd_SRP329695 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.47339 GTEX-PW2O-1226-SM-48TCH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 l-type Phosphosite Textmining Biological Term Annotations 1.0 null inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.934918 striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.944507 photosynthetic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 3.27228 marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069707 Corpus striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.093 central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050923 GTEX-WFG8-2126-SM-3GIKQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 AXIN2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00437227 Dorsal striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.829 posteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47755 GSE207611,GSE207612_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XQ3S-0626-SM-4BOOB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.952547 BRD-K06398048 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25771 ventral endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13896 stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.345558 hsa-miR-3130-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null DMS53 CCLE Cell Line Gene CNV Profiles -1.0 -1.95735 GSE150665,GSE150667_4_v_8_mysm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.4162 PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL3-OVERLAP_GENES_PAX5 Rummagene Transcription Factor Associations 2026 1.0 null occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1124 PMC4154952__F5 PFOCR Pathway Figure Associations 2023 1.0 null hsluv protease complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.712795 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.841472 BRD-K30973947 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11881 CRCGN008_HEPG2_24H:C24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.6925 muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050988 GSE213588_8_v_2_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-K82324807 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15457 Limbic system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 form GeneRIF Biological Term Annotations 1.0 null GSE160083,GSE160084_2_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null SARS-BatSRBD_Day1_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.54008 Intelligence DisGeNET Gene-Phenotype Associations 1.0 null PMC11092745-media-2.xlsx-cGEP_Associated_Genes_Ranked-SOX4_TOX2_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20956 BRD-K17743125_belinostat_A375_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null calcium Phosphosite Textmining Biological Term Annotations 1.0 null inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.988067 BRD-U68942961_-666_SKB_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null corpus striatum TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE171175,GSE171181_1_v_2_e7107_human RummaGEO Drug Perturbation Signatures -1.0 null RNF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28894 lateral part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71098 GTEX-VJYA-0726-SM-4KL1T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929629 H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26544 GSE133087_1_v_2_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null dry eye syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.134792 CTV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null 2-aminobenzenesulfonamide-3063 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KOSC-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K21472066 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17136 PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null Carcinoma Of Lung DisGeNET Gene-Disease Associations 1.0 null GSE138001_0_v_4_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null Stria terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.212 Paragigantocellular reticular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09532 Cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.20936 abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.284065 Atrophy HuGE Navigator Gene-Phenotype Associations 1.0 null GSE210101,GSE210114_4_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null GSE121809_1_v_0_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null LAMTOR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51372 Acute lymphoblastic leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.257 bovine Phosphosite Textmining Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plastid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.472813 SPG11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73123 GTEX-QEG4-0008-SM-48TYZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-T6MO-1426-SM-4DM73 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Z8-1826-SM-3K2BH GTEx Tissue Sample Gene Expression Profiles 1.0 0.836923 skeletal muscle HPA Tissue Protein Expression Profiles 1.0 1.25705 BICR31 CCLE Cell Line Gene CNV Profiles -1.0 -1.32952 response to heat GO Biological Process Annotations 2015 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.55067 endocervix TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.247719 ES-WA7 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.14964 mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleolus COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.502 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A685-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02289 abductor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.326432 BRD-K85908443 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75378 LP1 DepMap CRISPR Gene Dependency 1.0 2.26994 Cocaine CTD Gene-Chemical Interactions 1.0 null NCIH1755 DepMap CRISPR Gene Dependency 1.0 2.36264 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5791 PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null GSE198794_2_v_3_usp18_human RummaGEO Gene Perturbation Signatures 1.0 null CRCGN017_MCF10A.WT.HP_24H:A13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.60535 telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.743801 primary bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.384079 BRD-K70183558 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11308 Perturb_15079_KD_Ash1l_SRP354984 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.76975 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 stamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.317679 Rhabdomyolysis CTD Gene-Disease Associations 1.0 1.17235 larva TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.113014 GTEX-S7PM-0011-R6A-SM-3NM8F GTEx Tissue Sample Gene Expression Profiles 1.0 0.871532 WARS2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00564752 ags cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.340757 pathogenic GeneRIF Biological Term Annotations 1.0 null cytosolic Phosphosite Textmining Biological Term Annotations 1.0 null PMC12311176-41408_2025_1333_MOESM2_ESM.xlsx-Table_S10-Table_S10_SOX11_SMARCA4-direct_target_genes_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null Medial temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.873 GTEX-PVOW-2526-SM-2XCF7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05589 light-harvesting complex, core complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.41867 MFE280 DepMap CRISPR Gene Dependency 1.0 2.09664 CRCGN016_MCF10A.TP53.M_24H:O10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.54128 posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.895304 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 paragonimiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.822897 GTEX-S32W-1426-SM-4AD66 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4824-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OPM-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.525 GTEX-PW2O-0226-SM-48TC7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 brain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 Substance Withdrawal Syndrome CTD Gene-Disease Associations 1.0 1.15661 PRKACA Hub Proteins Protein-Protein Interactions 1.0 null PRKACA PhosphoSitePlus Substrates of Kinases 1.0 null TSSK2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00492156 Mood disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 Lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 BRD-K62263376 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17465 musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04259 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K67011787 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54104 CARD9 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00535179 CIC LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00572045 BRD-K86293440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71328 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1165 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.517348 GSE189859,GSE189861_4_v_2_idh1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S4UY-0226-SM-3K2AP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7143 hsa-miR-575 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 CENPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20034 RUNX1 ChEA Transcription Factor Targets 1.0 null Erythema CTD Gene-Disease Associations 1.0 1.01587 Perturb_13532_KO_Mbnl3_SRP103934 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.06913 ARG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7088 photosystem i reaction center COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.689451 TCF3/E2A-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-FB-A7DR-01A-21R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasm LOCATE Curated Protein Localization Annotations 1.0 null SUDHL5 CCLE Cell Line Gene Expression Profiles 1.0 1.40494 PMC9314667-Table_1.xlsx-Regulons-SOX10_SOX10 Rummagene Transcription Factor Associations 2026 1.0 null SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null Alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.546 HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.41604 GTEX-XUW1-0226-SM-4BOOS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CDCP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31721 EKVX BioGPS Cell Line Gene Expression Profiles -1.0 -0.964122 SUZ12-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null VZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.842142 OUMS-23 COSMIC Cell Line Gene Mutation Profiles 1.0 null phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.09449 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14303 C2CD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10494 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QEL4-1326-SM-447AD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Gonorrhea DisGeNET Gene-Disease Associations 1.0 null BRD-K33462580 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02674 PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-U3ZH-0008-SM-4DXT2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-Q2AH-1626-SM-3GAF8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6232 Visual areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1003 Perturb_1758_KO_p300/Tet2_SRP250516 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.29473 caudate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.815233 GTEX-XQ8I-1926-SM-4BOOK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-V1D1-1026-SM-4JBHE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Single-stranded nucleic acid binding R3H InterPro Predicted Protein Domain Annotations 1.0 null BRD-K50004365 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21169 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24729 mice-inbred-c57bl Phosphosite Textmining Biological Term Annotations 1.0 null hsa-miR-4452 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 Weight Gain CTD Gene-Disease Associations 1.0 1.3314 striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.849959 BRD-K56536691 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08252 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1252 BRD-K46413323 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67693 496100318_PCx_probable Alzheimer's disease_TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.71165 Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleosomal methylation activator complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.661 TRPV2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00498025 CRCGN015_MCF10A.TP53.M_24H:N05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.31961 r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14538 SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.88455 Perturb_1170_KD_RUNX1_ERP128097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GTEX-U3ZM-0526-SM-4DXTB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 HOXB6 MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K11625057 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52274 FOS ENCODE Transcription Factor Targets 1.0 null PMC5550424-41467_2017_212_MOESM4_ESM.xlsx-Hematlas-Genesets-GSX1_GSX1 Rummagene Transcription Factor Associations 2026 1.0 null SP in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.831459 GSE141143_1_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K85235446 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20771 PMC11913834-Table2.xlsx-CEBPB_bound_geneset-Gene_CEBPB Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-330-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 FHL2_Deficiency_GDS3344_596_mouse_Spontaneously immortalized embryonic fibroblasts (EFs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CRCGN015_MCF10A.TP53.M_24H:H14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.22525 BRD-K38227596 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43828 occipital cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02289 BRD-K87343552 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40222 GSE157555,GSE157556_0_v_6_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE101112_0_v_4_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null nuclear viral factory COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.06549 oxidoreductase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.106505 PPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99371 Leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.333 GTEX-QEL4-0008-SM-447AZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-QDT8-0011-R10A-SM-32PKG GTEx Tissue Sample Gene Expression Profiles 1.0 0.905177 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.629242 GTEX-S4Z8-0008-SM-33HAZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 urinary bladder cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.412779 19377508-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.246046 BRD-K74305673_IMD 0354_SKLU1_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Proximal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.954 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null BMI-1_DEPLETION_GDS2445_115_human_embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null neostriatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.778155 BRD-K46961295 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08613 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2347 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC5263239-mmc2.xls-Overlaps-Genes_common_to_spreading_MLL-AF4_in_SEM_and_patient_cells_43_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4 Rummagene Transcription Factor Associations 2026 1.0 null protein-dna complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.286614 GTEX-WFJO-1926-SM-3GILA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 membrane-enclosed lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.502 germinal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.215534 ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.831547 H3K27ac_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mammary duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.254239 OMC-1 COSMIC Cell Line Gene CNV Profiles -1.0 -3.2703 GTEX-RU72-2926-SM-2TF66 GTEx Tissue Sample Gene Expression Profiles 1.0 0.874442 SARS-BatSRBD_Day7_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.75491 TAL1-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.99305 GTEX-XXEK-0004-SM-4BRWO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Cavitation DisGeNET Gene-Disease Associations 1.0 null periodontal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.54393 GTEX-PWOO-1526-SM-48TCK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6621 Type IC spiral ganglion neuron_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null TTK Kinase Library Serine Threonine Kinome Atlas 1.0 null GTEX-TMMY-1726-SM-4DXTD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE140607_0_v_6_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PWOO-0626-SM-48TZH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 SK&F 81297 CTD Gene-Chemical Interactions 1.0 null PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.970356 BRD-K57969466 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12853 Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.245 KCNIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00526 KYSE-510 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-1256 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Bipolar Disorder CTD Gene-Disease Associations 1.0 1.04611 H3K27me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8515_KO_Satb2_SRP068801 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.80572 GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles 1.0 1.87522 Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.584 GTEX-T8EM-0826-SM-4DM76 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45674 Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Piriform area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33166 Postsynaptic specialization membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.019 PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null P12ICHIKAWA CCLE Cell Line Gene Expression Profiles 1.0 1.6298 PMC3607232-mmc1.xls-MLLN_AF4_H3K79me2_RS411-MLL_AF4_H3K79me2_RS411_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null BRD-K66581298 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.23097 CRCGN008_HEPG2_24H:O02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.82525 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05827 Globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.169 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles 1.0 0.885462 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG Rummagene Transcription Factor Associations 2026 1.0 null GSE86507,GSE86509_3_v_9_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null CHRM1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00480492 Nmyc_OE_GDS2406_14_mouse_LUNG GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE142684_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null leaf epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.663149 TEAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7306 Fatigue CTD Gene-Disease Associations 1.0 1.20361 nucleic acid binding GO Molecular Function Annotations 2015 1.0 null GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE160817_7_v_9_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null Piriform area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03398 BRD-K94697940 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17047 GTEX-Q2AI-0626-SM-48TZU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02358 cytoplasm GO Cellular Component Annotations 2015 1.0 null GSE168807_0_v_8_dnmt3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE133213_6_v_13_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PWO3-0011-R5A-SM-2I5EZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.31352 GSE160304,GSE163392_4_v_3_zswim8_human RummaGEO Gene Perturbation Signatures -1.0 null BRD-K64822626_KUC104135 KUC104135N_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null substantia nigra, pars compacta, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03927 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -3.46119 TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5149 r3 part of parvicellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.50928 GSE142684_0_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.879089 skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles 1.0 1.19616 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26776 CRCGN016_MCF10A.TP53.M_24H:H19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.49598 HELA BioGPS Cell Line Gene Expression Profiles -1.0 -0.994955 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.31667 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15202 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29M-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^4_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.73954 GSE164874_5_v_1_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K40102258 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14049 Parabrachial nucleus, lateral division, central lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19619 GSE224096_2_v_0_cocaine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE92457_9_v_12_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null PSN1 CCLE Cell Line Gene CNV Profiles 1.0 1.38915 Proteinuria CTD Gene-Disease Associations 1.0 1.37132 ISG20 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00520151 GSE135350_3_v_5_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-3659 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 SCMCRM2 DepMap CRISPR Gene Dependency 1.0 3.01457 GSE162892_4_v_5_isox_human RummaGEO Drug Perturbation Signatures -1.0 null striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.47454 hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17284 cytochrome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.126647 Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-S3XE-0926-SM-4AD4S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE48812_3_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST-18959480-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null SKES1 CCLE Cell Line Gene Expression Profiles 1.0 1.95787 inner CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.868127 GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.04901 GAS2L3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00615143 GSE125219,GSE125221_4_v_0_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null Cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles 1.0 0.884339 FNBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55131 BRD-K50423606 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.62405 hsa-miR-4691-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 diencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.12117 striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.58192 Cerebellar nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11957 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.825115 Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_ZIC3_20872845 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.58412 PMC9894241-pnas.2211429119.sd05.xlsx-G8_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4255 signal Phosphosite Textmining Biological Term Annotations 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Neuronal dense core vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.868 GTEX-X585-0011-R3B-SM-46MVG GTEx Tissue Sample Gene Expression Profiles 1.0 0.877438 lateral ventricle HPA Tissue Protein Expression Profiles 1.0 1.25705 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77256 striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.46063 isthmic part of mesencephalic trigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06756 CD81 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00453675 BRD-K31606237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03399 Autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.324 PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U8XE-1126-SM-3DB8W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 External carotid artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.583 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCNK2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00572846 PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null PMC5770158-elife-31706-supp3.xls-ISL1_target_regions-Nearest_gene_2_ISL1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-TSE9-2626-SM-4DXV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Neurobehavioral Manifestations CTD Gene-Disease Associations 1.0 1.507 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 r3 part of magnocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49957 ChIP_RNF2_22325148 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CRCGN017_MCF10A.WT.HP_24H:O19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.899 gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-A68930007_-666_A375_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_6193_KO_Eed_SRP133646 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.927776 inflorescence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.537021 CRCGN015_MCF10A_48H:C24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.20772 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02332 hsa-miR-4753-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.84356 Retinitis Pigmentosa DisGeNET Gene-Disease Associations 1.0 null keratoconjunctivitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.110403 BRD-K74206117 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67495 Exanthema CTD Gene-Disease Associations 1.0 1.06008 MHHCALL2 CCLE Cell Line Gene Expression Profiles 1.0 1.86452 LB771-HNC GDSC Cell Line Gene Expression Profiles -1.0 -1.45618 CRCGN015_HEPG2_48H:L24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.42433 GSE112761,GSE112767_1_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE235701,GSE261434_2_v_3_enasidenib_human RummaGEO Drug Perturbation Signatures -1.0 null periplasmic space COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.807065 Perturb_4375_KD_CREBBP_SRP072506 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.61284 PMC5263239-mmc2.xls-MLL-AF4_Patient_Cells-Non-spreading_targets_gene_names_302_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null GSE214514_1_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GRIN2A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00449537 GSE93674_2_v_3_ezh2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles 1.0 1.55189 Rif1_KD_GDS4943_243_mouse_F1 embryonic stem cell (ESCs) line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.985297 IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ATF3_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles 1.0 0.86962 BHT-101 GDSC Cell Line Gene Expression Profiles -1.0 -3.51637 hsa-miR-501-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Irritable mood GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.769897 BRD-K41774018 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20341 chondrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.405176 Hypothalamus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.693 GSE81803,GSE81912_3_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null cefalotin-2517 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null thigh muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.306083 GTEX-T5JW-0326-SM-4DM6J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE169152_5_v_6_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.970356 Epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 PMC3607232-mmc3.xlsx-b_RUNX1_SEM_MLLC_H3K4Me3-x_2_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null Eye Abnormalities CTD Gene-Disease Associations 1.0 1.08231 Mixed phenotype acute leukemia, B/myeloid DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.199 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1269 HUG1N CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.72453 rapidly progressive glomerulonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.354131 cytoplasmic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.360515 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8516-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1492 Perturb_15080_KD_Chd8_SRP354984 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.34948 SUFU LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00685306 GTEX-U4B1-1226-SM-4DXT7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE147056_0_v_1_actl6b_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K73582217 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20532 BRD-K25097691 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1725 Pulmonary Edema CTD Gene-Disease Associations 1.0 1.54281 Perturb_2916_KD_FOXO1_SRP192099 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CRCGN015_MCF10A.WT.HP_24H:C07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.9637 KIF13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.91178 GSE248045,GSE248046_6_v_5_runx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null RARB-27405468-CHIP-SEQ-BRAIN-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SNAPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55154 intracellular part LOCATE Curated Protein Localization Annotations 1.0 null TEAD4-22529382-TROPHECTODERM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Atrophy CTD Gene-Disease Associations 1.0 1.36047 mRNA_NR2F2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CTCF_CTCF Rummagene Transcription Factor Associations 2026 1.0 null IA-LM GDSC Cell Line Gene Expression Profiles -1.0 -1.71848 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.047766 PMC4823079-oncotarget-07-2889-s002.xls-Feuil1-Supplementary_table_1_AEU_events_shared_by_DEK_and_WT1-expressing_cells_WT1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XYKS-0002-SM-4BRWN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.166485 cleavage Phosphosite Textmining Biological Term Annotations 1.0 null GSE165579_3_v_2_opa1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K88449712 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10553 BRD-K14702616 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29848 SH10TC DepMap CRISPR Gene Dependency 1.0 3.99086 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NG-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.60249 cellular response to heat GO Biological Process Annotations 2015 1.0 null GTEX-P44H-1126-SM-48TBU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.284 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.40808 Vomiting CTD Gene-Disease Associations 1.0 1.13484 BRD-K44403120 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30841 ZIC3-20872845-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CRAT LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00579245 hematopoietic system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Striatonigral neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.025 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15977 Perturb_6620_KO_NEUROD1_SRP388830 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.97104 BRD-K87275815 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.62835 GTEX-SNOS-0526-SM-4DM54 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K68890376 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2072 ALKBH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00435 UBE2L6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68787 CRCGN016_MCF10A.TP53.M_24H:P21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.50943 GTEX-Q2AG-0011-R6A-SM-2HML7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.82868 E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null biofilm matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.26166 Drug-Related Side Effects and Adverse Reactions CTD Gene-Disease Associations 1.0 1.82499 mucous cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.519647 lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.994422 IZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28529 Perturb_6176_KO_Opn1lw/Ep300_SRP201904 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.77488 Perturb_7075_KO_OGT_SRP252759 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.17467 Hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.09 hsa-miR-15a TargetScan Predicted Conserved microRNA Targets 1.0 0.598666 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null echocardiography GAD Gene-Disease Associations 1.0 null ABI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82867 GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 superficial stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02164 m2 part of substantia nigra compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05567 HMGA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22656 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14417 GTEX-QDVJ-1426-SM-48U1Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC3432194__F2 PFOCR Pathway Figure Associations 2023 1.0 null microtubule organizing center COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.090454 Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6857 temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.133557 endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2775 CRCGN011_HEPG2_24H:I24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.05255 BRD-K73427605 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6558 PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-gene_id_BCL6 Rummagene Transcription Factor Associations 2026 1.0 null occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0004 t-cell chronic lymphocytic leukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Infralimbic cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.642 GSE176555,GSE176556_1_v_0_acriflavine_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K11715561 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06406 ABCF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02961 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QEG4-0526-SM-48TZD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Anxiety Disorders CTD Gene-Disease Associations 1.0 1.03345 PRDM1 JASPAR Predicted Transcription Factor Targets 1.0 null Severe influenza A (H1N1) infection GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.769897 GSE89767_1_v_5_cebpa_mouse RummaGEO Gene Perturbation Signatures 1.0 null caudate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20138 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.876129 ZFP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14807 transmembrane transporter complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.077632 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.994924 GTEX-SSA3-0326-SM-32QPS GTEx Tissue Sample Gene Expression Profiles 1.0 0.918125 J-RT3-T3-5 GDSC Cell Line Gene Expression Profiles 1.0 1.69204 GTEX-QV31-0726-SM-3GAEG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE219195_0_v_2_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null Striatum dorsal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19572 hsa-miR-3611 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GSE205163,GSE205164_9_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null SPI1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE210101,GSE210114_1_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null BRD-K55679243 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21744 H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K57489406 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30818 RD GDSC Cell Line Gene Expression Profiles 1.0 2.47307 hsa-miR-2053 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null A4/FUK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7054 BRD-K01691949 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38796 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.52936 GSE126345_9_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE133213_6_v_5_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE240896,GSE240899_2_v_4_ccnt1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE210580_4_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_2_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XUJ4-1526-SM-4BONU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Hydronephrosis CTD Gene-Disease Associations 1.0 1.11911 BRD-K75999307_NCGC00182357-01_A549_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null EGFR_druginhibition_82_GSE27638 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.4255 UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE164874_5_v_11_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR Rummagene Transcription Factor Associations 2026 1.0 null Major depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 BRD-K60052521 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20929 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.87849 periodontium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.452969 PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS Rummagene Transcription Factor Associations 2026 1.0 null fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.29851 GTEX-RN64-0008-SM-48FEZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 strychnine-hcl LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.63029 cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null FRMD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37724 Breast Neoplasms CTD Gene-Disease Associations 1.0 1.1908 GTEX-PWOO-0326-SM-48TDB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 22RV1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Medulla oblongata TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.299 GTEX-TSE9-0526-SM-3DB7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.03791 ONDA9 DepMap CRISPR Gene Dependency 1.0 6.61697 EW-3 GDSC Cell Line Gene Expression Profiles 1.0 1.50013 BRD-K63856509 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09128 GSE234637_1_v_0_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-PX3G-0008-SM-48U2L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WWYW-0011-R1A-SM-3TW8G GTEx Tissue Sample Gene Expression Profiles 1.0 0.895419 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07593 Lymphoid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.302 excretory gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null biceps TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.371619 BRD-K81418486_vorinostat_HCC15_6.0_h_11.1_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null amygdaloid complex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02944 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cardiomyopathies CTD Gene-Disease Associations 1.0 1.11325 Echocardiography dbGAP Gene-Trait Associations 1.0 0.117437 GSE129370_2_v_1_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null WDR86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87302 GSE165579_0_v_1_opa1_mouse RummaGEO Gene Perturbation Signatures 1.0 null laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45418 Human - Bone Marrow - L2 - Transitional B HuBMAP Azimuth Cell Type Annotations 1.0 null lung TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.853788 GLIS3_KO_GDS3812_500_mouse_Embryonic pancreas at E15.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.304533 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25648 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57446 PMC6319725-pone.0204197.s006.xlsx-Table_S2-S2_TABLE_-_Operon_Expression_and_SOM_clustering_data_for_Gene_Set_identified_by_ANOVA_p_0_005_1005_genes_FDR_8_8_GRHL3 Rummagene Transcription Factor Associations 2026 1.0 null hematopoietic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05427 hemangioblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.716021 BRD-K41355409 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38737 Telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Anteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22729 outer CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.829684 GTEX-XQ8I-0926-SM-4BOOF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 viscus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-X638-0326-SM-47JY1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18696 GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles 1.0 0.860718 GSE138001_5_v_4_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.027465 NCI-H661 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H446 GDSC Cell Line Gene Expression Profiles 1.0 1.53461 GSE115542_5_v_3_digoxin_human RummaGEO Drug Perturbation Signatures 1.0 null SW780 COSMIC Cell Line Gene Mutation Profiles 1.0 null Coronary Artery Disease CTD Gene-Disease Associations 1.0 1.14713 GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles 1.0 0.911829 hsa-miR-424 TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 Psoriasis vulgaris_Skin tissue_GSE13355 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.75806 epithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053609 GSE239578_0_v_3_cxadr_mouse RummaGEO Gene Perturbation Signatures -1.0 null Movement Disorders CTD Gene-Disease Associations 1.0 1.15022 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.969451 GATA2 ChEA Transcription Factor Targets 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_0Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.839753 GTEX-PX3G-2026-SM-48U1H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5164 VZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33278 Lung TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-W5X1-2326-SM-3GIL6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.083184 GTEX-S7SE-0011-R7A-SM-2XCDI GTEx Tissue Sample Gene Expression Profiles 1.0 1.90016 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.07147 GTEX-S4Q7-0926-SM-4AD5D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Myocardial Infarction CTD Gene-Disease Associations 1.0 1.14336 GTEX-NL4W-0011-R5a-SM-2I3GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.4139 pre-B cell receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.925 GTEX-RVPV-0011-R11A-SM-2TF6F GTEx Tissue Sample Gene Expression Profiles 1.0 1.07761 Trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 3.934 Fatty Liver CTD Gene-Disease Associations 1.0 1.74681 GTEX-SE5C-1226-SM-4BRWV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K08006576 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45115 GSE169152_3_v_7_ibrutinib_human RummaGEO Drug Perturbation Signatures -1.0 null EMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05884 496100470_HIP_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.1364 GSE147366_1_v_2_med13_human RummaGEO Gene Perturbation Signatures -1.0 null CRCGN011_HEPG2_24H:K13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.0925 BRD-K30310320 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09755 disease of mental health GWASdb SNP-Disease Associations 1.0 0.058874 Perturb_4591_KO_Ezh2/Runx1/Flt3_SRP066416 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.93523 BRD-K73637411 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07071 Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31293 VZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10113 mRNA_SMAD1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SKNDZ DepMap CRISPR Gene Dependency 1.0 2.56615 respiratory chain COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.268237 SLVL COSMIC Cell Line Gene Mutation Profiles 1.0 null Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null SLC6A8 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00609852 GSE126219_0_v_1_haloperidol_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.988258 gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.720373 COLO-741 GDSC Cell Line Gene Expression Profiles -1.0 -1.49187 Perturb_4418_KO_Eed_SRP172483 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.1103 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.606112 REH CCLE Cell Line Gene Expression Profiles 1.0 2.25278 H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pars reticulata TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.949 Hyperkinesis CTD Gene-Disease Associations 1.0 1.2861 GSE164874_5_v_12_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null Liver Neoplasms CTD Gene-Disease Associations 1.0 1.29256 lymphatic system disease GWASdb SNP-Disease Associations 1.0 0.452001 GSE253795_1_v_0_alkbh5_human RummaGEO Gene Perturbation Signatures 1.0 null Neural Tube Defects CTD Gene-Disease Associations 1.0 1.19412 BRD-K73581966 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6096 Waist-to-hip ratio adjusted for BMI GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0301 striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21311 BRD-K41026056 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17341 rhabdoid cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.32009 cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.31818 MDAMB436 CCLE Cell Line Gene Expression Profiles -1.0 -1.6707 GTEX-R45C-1226-SM-48FEE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.111091 SLU7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10788 GTEX-N7MT-0011-R6a-SM-2I3G3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.60836 periventricular stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12309 WDR89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19429 ADCY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81167 Lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05771 ZNF384 ENCODE Transcription Factor Targets 1.0 null GTEX-QMR6-0011-R7A-SM-32PKL GTEx Tissue Sample Gene Expression Profiles 1.0 1.28737 GSE221633_0_v_1_trim24_human RummaGEO Gene Perturbation Signatures 1.0 null PSG2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0051187 Necrosis CTD Gene-Disease Associations 1.0 2.08894 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.9481 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null Asthma GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.504576 SUPT20H LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00490563 GSE216273,GSE216292_0_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null A2058 COSMIC Cell Line Gene Mutation Profiles 1.0 null Endopeduncular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.863 Perturb_13056_Mut|OE_Sik3E13_SRP334442 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.2847 rat Phosphosite Textmining Biological Term Annotations 1.0 null hsa-miR-4676-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Postpiriform transition area, layers 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47369 Attention deficit hyperactivity disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.908 B-lymphoblastic leukemia/lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.15 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.073 hsa-miR-4661-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 BRD-K85802892 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.04018 Perturb_1183_KD_RUNX1_ERP128097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 RUNX2 JASPAR Predicted Transcription Factor Targets 1.0 null endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.310421 light-harvesting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.33087 GSE206516,GSE206518_5_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures 1.0 null calmodulin binding GO Molecular Function Annotations 2015 1.0 null GTEX-R55C-1626-SM-48FEG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Amygdala TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 gastric cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.114564 GTEX-XYKS-1326-SM-4BRUN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-S7SE-0011-R6A-SM-2XCD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.90472 GSE218060_7_v_4_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null squamous epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.514924 skeletal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.451042 NCI-SNU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null AMT LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00545915 H3K27me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.998142 PDE6B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00524965 BMI1-23680149-NPCS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K16421840 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.23259 PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF Rummagene Transcription Factor Associations 2026 1.0 null SF268 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE215314_0_v_1_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4465 TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 USF MotifMap Predicted Transcription Factor Targets 1.0 null WT1-25993318-PODOCYTE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-PWOO-1226-SM-48TCO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055542 GTEX-PX3G-1526-SM-48U11 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-WZTO-0011-R6B-SM-4E3J6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.59416 GTEX-T6MO-1026-SM-4DM72 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-3714 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GSE142019,GSE142021_1_v_3_ythdf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC5398616__F3 PFOCR Pathway Figure Associations 2024 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.475 GTEX-OXRO-1226-SM-48TDL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-128 TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 GJB4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00582424 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null t60-adrenal_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.67803 SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-SE5C-0326-SM-4BRWX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-T6MN-0008-SM-4DM7H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K29655991 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08321 abnormality of the coronary arteries GWASdb SNP-Phenotype Associations 1.0 0.304211 PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SNB19 CCLE Cell Line Gene CNV Profiles 1.0 1.33266 GSE154961,GSE154963_4_v_0_chd4_human RummaGEO Gene Perturbation Signatures -1.0 null cam Phosphosite Textmining Biological Term Annotations 1.0 null JHOS2 CCLE Cell Line Gene CNV Profiles 1.0 1.76159 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.484 cortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.986085 RGMB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27614 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE224294_4_v_2_ngly1_human RummaGEO Gene Perturbation Signatures -1.0 null glomerular epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.216325 P12-ICHIKAWA GDSC Cell Line Gene Expression Profiles 1.0 1.4492 prenatal maternal abnormality GWASdb SNP-Phenotype Associations 1.0 0.383023 GTEX-QESD-0008-SM-447B2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE160083,GSE160084_1_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.926692 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.545 GSE115363_2_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null AIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9415 PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K47694606 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39667 olfactory tubercle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.673321 BRD-K64137284 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49565 GATA1 ChEA Transcription Factor Targets 1.0 null POLE2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00316279 RAI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64977 GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles 1.0 0.966715 Paraventricular nucleus of hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.661 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.50773 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1529 GTEX-N7MT-0326-SM-48TDP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 dorsal motor nucleus of the vagus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.898417 GTEX-U3ZN-0926-SM-4DXTU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K88936403 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00226 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.80325 organelle LOCATE Predicted Protein Localization Annotations 1.0 null GSE248045,GSE248046_0_v_5_runx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-A96536816 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17493 HUO-3N1 COSMIC Cell Line Gene Mutation Profiles 1.0 null arterial stenosis GWASdb SNP-Phenotype Associations 1.0 0.241782 SJRH30 COSMIC Cell Line Gene Mutation Profiles 1.0 null periapical periodontitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.949102 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1811 GTEX-XXEK-2426-SM-4BRUS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL1-CLOSEST_GENE_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null PMC9882185-media-4.xlsx-Neuron_KD-ID_AR Rummagene Transcription Factor Associations 2026 1.0 null TEAD4 ChEA Transcription Factor Targets 1.0 null GTEX-Q2AG-0008-SM-48U2K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.913601 intellectual GeneRIF Biological Term Annotations 1.0 null NCI-H2126 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC12549544-mmc2.xlsx-AA_D7_VS_D14-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null KE37 CCLE Cell Line Gene Expression Profiles 1.0 1.50238 NCIH446 CCLE Cell Line Gene Expression Profiles 1.0 1.58913 Infantile neuronal ceroid lipofuscinosis_Brain_GSE6678 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.48652 thorax TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055623 Perturb_8504_KO_Hr_SRP200420 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.78903 GSE135350_3_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.101622 carotid artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.234302 GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03519 C32 DepMap CRISPR Gene Dependency 1.0 2.15905 Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.20992 CRCGN017_MCF10A.WT.HP_24H:O15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.37315 HCFC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81204 MDAMB134VI CCLE Cell Line Gene CNV Profiles -1.0 -1.52217 GTEX-P4QR-0726-SM-2I5GO GTEx Tissue Sample Gene Expression Profiles 1.0 1.10849 GTEX-S341-1526-SM-4AD6K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE261563_6_v_1_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-4494 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 PMC3729040-NIHMS474885-supplement-1.pdf-19-SMAD1_SMAD1 Rummagene Transcription Factor Associations 2026 1.0 null GSE229468,GSE229471_0_v_1_znf587_human RummaGEO Gene Perturbation Signatures 1.0 null olfactorybulb BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868545 PMC9883165-41375_2022_1744_MOESM4_ESM.xlsx-CEBP_gene_module-CEBP_gene_module_with_gene_expression_data_and_ChIP_target_status_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null GSE92457_9_v_10_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57036 SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null extracellular region part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.058951 SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Vascular Malformations CTD Gene-Disease Associations 1.0 1.09998 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35198 r6 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04339 mouse Phosphosite Textmining Biological Term Annotations 1.0 null BRD-K67319345 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5453 GTEX-Q2AH-0926-SM-48TZK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CRCGN015_MCF10A.WT.HP_24H:P17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.15175 hsa-miR-26a TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 Hypertriglyceridemia CTD Gene-Disease Associations 1.0 1.36876 Nuclear lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.502 connective tissue cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048434 GTEX-UPIC-1026-SM-4IHLT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-XQ3S-1726-SM-4BOOD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-618 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 hsa-miR-4693-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Eukaryotic translation initiation factor 4F complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.05 plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.24253 GTEX-WL46-0011-R10A-SM-3MJFQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.03658 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2773 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-R55E-0011-R7A-SM-2TC5Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.59018 nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.908387 GSE126402_2_v_0_tal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null fluoxetine_mus musculus_gpl1261_gse35765 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GRK4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00418299 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.973706 bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.743165 respiratory system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K03467766 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1364 GSE149442_1_v_0_gdpd3_mouse RummaGEO Gene Perturbation Signatures 1.0 null SK-MEL-24 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05904 parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.998425 GTEX-WFG7-0526-SM-3GIKI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.437989 monocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.082904 MKNK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89495 acute lymphoblastic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068204 gastric adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.298883 hsa-miR-515-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE128634,GSE128636_4_v_0_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE48812_7_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null deletion GeneRIF Biological Term Annotations 1.0 null MHH-CALL-2 GDSC Cell Line Gene Expression Profiles 1.0 1.94738 GTEX-V1D1-0926-SM-4JBHQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CRCGN016_MCF10A.TP53.M_24H:P24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.32735 GTEX-QVUS-0626-SM-447CC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-PLZ4-0008-SM-48TE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE205687_1_v_0_mta1_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-1236 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 Primary B cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.923352 Atherosclerosis CTD Gene-Disease Associations 1.0 1.81036 NCI-H1355 GDSC Cell Line Gene Expression Profiles -1.0 -1.49557 GTEX-N7MS-0011-R5a-SM-2HMK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68224 psi associated light-harvesting complex i COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.403637 dorsolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.929029 GSE198826,GSE198911_1_v_2_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null bonemarrow_6b HPA Tissue Sample Gene Expression Profiles 1.0 0.889538 ZNF157 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98424 GSE151612_4_v_8_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null tcf3_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.14524 lymphocytic leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064682 white matter of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37623 artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.540981 germ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.168663 SMAD4 ChEA Transcription Factor Targets 1.0 null gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.082148 KLF5-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE182179_5_v_4_kdsr_human RummaGEO Gene Perturbation Signatures -1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50505 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sporozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.397222 GSE229580_2_v_3_creb1_human RummaGEO Gene Perturbation Signatures 1.0 null Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.102 thylakoid light-harvesting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.719015 periventricular stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37393 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RNOR-1226-SM-48FDQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF Rummagene Transcription Factor Associations 2026 1.0 null FAM110C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00903 limbic system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE182680,GSE182683_5_v_9_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null Renal Insufficiency CTD Gene-Disease Associations 1.0 1.08407 GTEX-WFON-0426-SM-3GIL4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 TIA1_KO_GSE54418_267_mouse_spinal cord GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SK-MES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null TP53INP2_OE_GDS5053_312_mouse_Skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Caudate putamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.494 Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14334 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4713_KO_Hnrnpu_SRP331236 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.92102 NCI-H2171 COSMIC Cell Line Gene Mutation Profiles 1.0 null cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.58588 Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ALAS2_OE_GDS2118_74_human_Blood GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K16937802 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06318 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 2.1002 benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.525746 Huntington's Disease_Lymphocyte_GSE8762 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.67115 PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null hemangioma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.673917 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9978 GTEX-S33H-1226-SM-4AD69 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 mantle zone of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18986 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7842-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202434,GSE202438_12_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null Skin Neoplasms CTD Gene-Disease Associations 1.0 1.06952 H3K27me3_Fetal Heart Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-SUCS-0008-SM-4DM53 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-6546-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUW1-1726-SM-4BOOZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Human - Tonsil - L2 - preT HuBMAP Azimuth Cell Type Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-7656-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Olfactory tubercle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.515 ChIP_REST_18959480 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.306 neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.836156 Age-related cognitive decline (global cognition) (slope of z-scores) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.6 BRD-K96218803 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1993 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.81193 cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.458241 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56818 Peritonitis CTD Gene-Disease Associations 1.0 1.01212 GTEX-SJXC-0008-SM-4DM7G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Human - Fetal Development - L1 - SATB2_LRRC7 positive cells HuBMAP Azimuth Cell Type Annotations 1.0 null SCA1_Knock-in_GDS3544_562_mouse_Cerebellum - 12 Weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K59064238 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30269 okadaic Phosphosite Textmining Biological Term Annotations 1.0 null GSE202434,GSE202438_7_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-K46298074 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18499 GSE174498,GSE174500_5_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19C-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GSE196962_2_v_6_parg_human RummaGEO Gene Perturbation Signatures 1.0 null Ltk TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.637 PMC9075502-crc-21-0022-s07.xlsx-WT_vs_KD-Unnamed_0_AR Rummagene Transcription Factor Associations 2026 1.0 null exocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.415434 GTEX-P44H-0726-SM-48TBT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE107956,GSE107957_0_v_1_ythdf2_human RummaGEO Gene Perturbation Signatures -1.0 null PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF638 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55007 GTEX-X4LF-0006-SM-3NMCO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 posteroventral (inferior) parietal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02808 GTEX-R55C-0008-SM-48FCF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 MYC ENCODE Transcription Factor Targets 1.0 null GSE160817_3_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-502-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 periodontal ligament TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.457214 posteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30523 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.61793 Prenatal Injuries CTD Gene-Disease Associations 1.0 1.34285 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21784 PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-TMZS-0008-SM-47JWM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-3129-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.265648 levetiracetam_rattus norvegicus_gpl1355_hippocampus_gds1864 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-W5WG-0008-SM-4KL25 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE94849_6_v_2_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A184-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WZTO-0011-R10B-SM-4E3KB GTEx Tissue Sample Gene Expression Profiles 1.0 0.936361 CEBPZ_01_75 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.67014 BRD-K42697646 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.96567 GTEX-PWCY-0926-SM-48TD7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K38493972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03536 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03398 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.688576 sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.181222 Lung squamous cell carcinoma_LUSC_TCGA-18-4721-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Striatal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.721 GTEX-V1D1-2426-SM-3GAER GTEx Tissue Sample Gene Expression Profiles 1.0 1.18544 CRCGN017_MCF10A.WT.HP_24H:A21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.1319 KDM2B-26808549-CHIP-SEQ-DND41-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K27172015 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19957 leg muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.499223 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.889124 tet1_21295276_mesc_v6.5_lof_mouse_gpl6887_gse26900 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.110445 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.976341 NEC8 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RM2N-0726-SM-48FD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.71925 GTEX-PLZ4-0226-SM-2S1NW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13286 GSE166315_1_v_0_docetaxel_mouse RummaGEO Drug Perturbation Signatures -1.0 null BRD-K78003637 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46078 intermediate stratum of r1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03161 Adult body size GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.9 A253 GDSC Cell Line Gene Expression Profiles -1.0 -1.59944 shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.680656 GSE129244_3_v_1_lmo2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE188884,GSE189078_2_v_3_ebf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE169152_5_v_4_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null KLF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62201 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE208254_3_v_2_irf8_mouse RummaGEO Gene Perturbation Signatures 1.0 null SIRT6 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00582165 Acute Myeloid Leukemia_LAML_TCGA-AB-2946-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1 Rummagene Transcription Factor Associations 2026 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP1_FOXP1 Rummagene Transcription Factor Associations 2026 1.0 null dorsal motor nucleus of the vagus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.876324 dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.10837 HCC364 CCLE Cell Line Gene Expression Profiles -1.0 -1.92635 NCIH1385 CCLE Cell Line Gene CNV Profiles -1.0 -1.43784 Adult Oligodendroglioma DisGeNET Gene-Disease Associations 1.0 null Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE5786 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.06288 Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20138 wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.048951 Dyslipidemias CTD Gene-Disease Associations 1.0 1.05052 integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.194045 BRD-K84015265 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15831 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.48645 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.88455 GSE142684_0_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL3-CLOSEST_GENE_PAX5 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-501-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.77847 NCIH209 CCLE Cell Line Gene CNV Profiles -1.0 -1.60319 GTEX-QVJO-0011-R5A-SM-2S1QM GTEx Tissue Sample Gene Expression Profiles 1.0 1.78425 medial (main) part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81539 GTEX-RWSA-0626-SM-2XCBD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.081 urinary tract TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adrenal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077472 HL60 BioGPS Cell Line Gene Expression Profiles 1.0 1.89634 H3K9me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CRCGN015_MCF10A.TP53.M_24H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.26035 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.76653 arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.269585 GSE169691_1_v_2_saha_mouse RummaGEO Drug Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11588 childhood kidney neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.126497 GTEX-Q734-0726-SM-48TZP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 substantia nigra TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.281423 syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.060728 Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31117 external encapsulating structure COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.22173 PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null BRD-K59683187 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42211 GSE210911_1_v_0_crem_human RummaGEO Gene Perturbation Signatures -1.0 null CRCGN016_MCF10A.TP53.M_24H:P10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.84234 GSE149880_2_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4 Rummagene Transcription Factor Associations 2026 1.0 null GSE84678,GSE93902_3_v_0_bcl11b_human RummaGEO Gene Perturbation Signatures -1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11045 retrocerebral complex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.246442 CRCGN011_HEPG2_24H:A09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.0307 H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XV7Q-0008-SM-4BRWL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE210101,GSE210114_6_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null striatal part of olfactory tuberculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02289 Immunosuppression DisGeNET Gene-Disease Associations 1.0 null lymphoblastic leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067678 OccipitalLobe BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.879979 BRD-U51024685_HG-6-64-01_HS578T_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null HNF1A_OE_GDS1499_252_human_HEK293 embryonic kidney cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.77 Sodium Measurement DisGeNET Gene-Phenotype Associations 1.0 null SBK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79252 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.43274 amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08042 hsa-miR-4470 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 TK COSMIC Cell Line Gene Mutation Profiles 1.0 null Human Immunodeficiency Virus DisGeNET Gene-Disease Associations 1.0 null lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.372587 nucleus Phosphosite Textmining Biological Term Annotations 1.0 null 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.66472 plastid thylakoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.583012 lymph node TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07831 DU145 CCLE Cell Line Gene Expression Profiles -1.0 -1.45641 Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neutrophil TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.250627 clathrin-sculpted vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.959 r4 part of magnocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1012 nephronophthisis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.272241 r9 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15412 Subceruleus nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3904 tail of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.98271 GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles 1.0 0.825143 PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC Rummagene Transcription Factor Associations 2026 1.0 null MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41015 hsa-miR-4638-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Disease Progression HuGE Navigator Gene-Phenotype Associations 1.0 null YTHDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77265 lung TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null VZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55366 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.98212 Perturb_8513_KO_Setd1b_SRP328849 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.77772 GTEX-SN8G-0008-SM-4DM4X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 STAT3 ENCODE Transcription Factor Targets 1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.301054 cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.62089 GTEX-PWN1-1526-SM-48TDA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.243918 GSE174498,GSE174500_2_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null encompassing GeneRIF Biological Term Annotations 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05417 GSE132948,GSE132949_2_v_5_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_2273_KO_Mettl3_SRP110576 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Hippocampus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.59405 GSE218060_2_v_4_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.439 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NB-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE135350_3_v_7_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K43969492 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.8123 mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.889554 tibialis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.446422 BRD-K55877261 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02093 GSE210580_4_v_6_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PL4 DepMap CRISPR Gene Dependency 1.0 3.31683 BRD-K77101974 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4891 Inflammation CTD Gene-Disease Associations 1.0 1.9492 GSE126402_1_v_6_tal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE180277_0_v_1_bach2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QVUS-0226-SM-3GIJY GTEx Tissue Sample Gene Expression Profiles 1.0 0.862816 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.899056 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null TE8 CCLE Cell Line Gene Expression Profiles -1.0 -2.36651 hypopharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.221989 GTEX-PVOW-1626-SM-48TC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-WZTO-0011-R3B-SM-3NMC6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.855375 BRD-K67868012_PI-103_HS578T_3_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-TMMY-2226-SM-4DXTN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Perturb_15618_KO_Mss51_SRP215371 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.96974 TEC LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00587 ventral globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.216528 BRD-K99172965 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02853 Small Intestine - Terminal Ileum GTEx Tissue Gene Expression Profiles 2023 1.0 2.76028 telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-326 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles 1.0 1.08984 GTEX-U3ZH-1926-SM-4DXTR GTEx Tissue Sample Gene Expression Profiles 1.0 1.15191 HUH7 DepMap CRISPR Gene Dependency 1.0 3.01846 Synucleinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.384 Developmental disorder of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.908 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.544549 Epitrochlearis muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.033 viral factory COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.06549 nevoid basal cell carcinoma syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.37555 Lyf-1 MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K41939184 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45023 ChIP_SALL4_18804426 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142684_3_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.258243 intermediate stratum of the PBC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17188 BCKDK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82006 JHH-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null srf_20709909_hematopoietic_stem_cell_lof_mouse_gpl1261_gds3732 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.00438 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.994154 GTEX-QV31-0626-SM-447C5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 skeletal muscle HPA Tissue Gene Expression Profiles 1.0 1.29867 GSE182680,GSE182683_7_v_8_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE213588_8_v_4_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null Amygdala BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.0516 blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.89647 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100278_FWM_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.94278 plasmacytoid dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.198272 PMC5398616__F3 PFOCR Pathway Figure Associations 2023 1.0 null SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36496 GTEX-Q2AI-0226-SM-48U1D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles 1.0 0.977425 BRD-K52245873 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22263 Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8654_KO_ESRRA/ESRRG_SRP304242 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CRCGN009_HEPG2_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.86476 PMC8197658-NIHMS1703954-supplement-Table_S4.xls-Sheet1-Table_S4_List_of_differentially_expressed_genes_near_which_SALL4_CUT_RUN_peaks_were_annotated_related_to_Figure_3_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null PMC9314667-Table_1.xlsx-Regulons-SOX11_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-TSE9-0008-SM-4DXT8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE210101,GSE210114_4_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null Respiratory system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cytosolic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.073899 endopeduncular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.308612 neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.141304 GSE210101,GSE210114_8_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null hereditary renal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.05807 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.863307 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NH-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15861_KD_ETS1_SRP270313 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 IDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01472 EW16 DepMap CRISPR Gene Dependency 1.0 3.82993 cell part GO Cellular Component Annotations 2015 1.0 null PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_significantly_downregulated_739_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null globe disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.199681 nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.182695 GSE169155_6_v_4_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null ALL-PO GDSC Cell Line Gene Expression Profiles 1.0 2.35675 PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XAJ8-1426-SM-47JYM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 ACHN BioGPS Cell Line Gene Expression Profiles -1.0 -1.64196 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052404 hypocotyl TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.716651 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1711_KO_Chd4_SRP193857 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.74262 chloroplast part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.371216 GSE202434,GSE202438_2_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.29434 BRD-K14732209 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03079 PMC3348545-NIHMS263168-supplement-3.pdf-73-SATB1_SATB1 Rummagene Transcription Factor Associations 2026 1.0 null CRCGN015_MCF10A.TP53.M_24H:M07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.2458 GSE218060_1_v_4_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null brain_3c HPA Tissue Sample Gene Expression Profiles 1.0 1.86266 GSE182179_0_v_1_kdsr_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WFG8-0926-SM-3GIKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-X4XX-0011-R5A-SM-46MWN GTEx Tissue Sample Gene Expression Profiles 1.0 1.04047 GTEX-UPK5-1826-SM-3GAEB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.93662 GTEX-OHPN-2726-SM-2I5H4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01985 BRD-K42526449 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12072 GSE176008_8_v_5_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WWYW-3126-SM-3NB39 GTEx Tissue Sample Gene Expression Profiles 1.0 0.846174 GSE125219,GSE125221_4_v_2_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null GSE182680,GSE182683_0_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null uroepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.34371 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.756 Alzheimer Disease HuGE Navigator Gene-Phenotype Associations 1.0 null GSE211983_0_v_3_nicotine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Viscus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-S341-1026-SM-4AD71 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CPCN CCLE Cell Line Gene CNV Profiles -1.0 -1.49385 hsa-miR-188-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XQ3S-0926-SM-4BOPI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE239578_5_v_7_cxadr_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K12743035 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5215 Perturb_6328_KO_Hdac4_SRP166864 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.6469 SALL4-18804426_ESC-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null response to stimulus GO Biological Process Annotations 2015 1.0 null GTEX-T6MO-1526-SM-4DM57 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 breast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057289 GSE84678,GSE93902_3_v_2_bcl11b_human RummaGEO Gene Perturbation Signatures -1.0 null response to temperature stimulus GO Biological Process Annotations 2015 1.0 null GSE129244_3_v_5_lmo2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE218060_1_v_0_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null immunology Phosphosite Textmining Biological Term Annotations 1.0 null GSE133070_3_v_1_prss1_mouse RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1018 BRD-K63209730 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32554 GTEX-XQ3S-1126-SM-4BOPK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE142684_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-Q2AG-0011-R7A-SM-2HMJP GTEx Tissue Sample Gene Expression Profiles 1.0 1.46393 CRCGN016_MCF10A.WT.HP_24H:B19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.18201 GSE133505_5_v_4_myf6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2712-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K78438852 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00275 HEC1B CCLE Cell Line Gene CNV Profiles 1.0 1.89656 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.5891 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44979 nervous system phenotype MPO Gene-Phenotype Associations 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.908863 KARPAS422 CCLE Cell Line Gene CNV Profiles 1.0 1.64802 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Perturb_15082_KD_Ehmt1_SRP354984 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -13.3074 plastid thylakoid membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.610778 abnormal synaptic transmission MPO Gene-Phenotype Associations 1.0 null proteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.132281 GSE119345_0_v_3_bexarotene_human RummaGEO Drug Perturbation Signatures 1.0 null Amyotrophic lateral sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.38 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3411 GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles 1.0 0.887132 Disease Models, Animal CTD Gene-Disease Associations 1.0 1.13552 GTEX-T2IS-0011-R5A-SM-32QP4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.96158 GFER LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00460145 SKRC20 CCLE Cell Line Gene Expression Profiles -1.0 -1.77304 GSE133087_5_v_0_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 Heart Defects, Congenital CTD Gene-Disease Associations 1.0 1.04389 tobacco use disorder GAD Gene-Disease Associations 1.0 null 18223198-TableS3 GeneSigDB Published Gene Signatures 1.0 null adult TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.579216 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r5 part of magnocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41622 hsa-miR-4704-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X261-0011-R5A-SM-3NMB4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.967163 Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE120612_7_v_1_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null RERFLCAI CCLE Cell Line Gene CNV Profiles 1.0 1.69345 T47D CCLE Cell Line Gene CNV Profiles 1.0 1.66466 Acute Lymphocytic Leukemia DisGeNET Gene-Disease Associations 1.0 null GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE202434,GSE202438_7_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null TE14 CCLE Cell Line Gene Expression Profiles -1.0 -1.79656 GTEX-R55G-0226-SM-48FEI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC12789432-41467_2025_66251_MOESM4_ESM.csv--SOX2_tumorigenesis_signature_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null PMC8987207-DataSheet_1.xls-HEB_targets_Fig_2B-HEB_Activation_FC_1_5_ttest_0_05_shRNA_HEB_in_Jurkat_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null r6 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10592 icSARS-Cov_Day7_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.85519 GSE145915_5_v_1_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary systemic mycosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.105527 GSE234637_2_v_0_ikzf1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QDT8-0011-R7A-SM-32PKF GTEx Tissue Sample Gene Expression Profiles 1.0 2.21603 BRD-K58407898 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13296 BRD-A94756469_DIGOXIN_A375_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles 1.0 1.11328 plant embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.714189 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.3896 BRD-K67727634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32251 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.207245 18801183-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null Insulin Resistance CTD Gene-Disease Associations 1.0 1.08868 GSE109530,GSE109531_2_v_3_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE129370_0_v_1_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066706 PMC10204296-13578_2023_1034_MOESM16_ESM.xlsx-Black-ZNF671_ZNF671 Rummagene Transcription Factor Associations 2026 1.0 null GSE240896,GSE240899_10_v_0_ccnt1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE159678_4_v_2_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-RM2N-0126-SM-48FDD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC5263239-mmc2.xls-KOPN-8_-_MLL-ENL-Non-spreading_targets_gene_names_1358_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null layer 2 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28276 chloroplast thylakoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.588037 BRD-K26079895 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49953 MET_knockout_249_GDS3148 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.87992 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14072 atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.304211 cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902071 POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4788 GTEX-Q734-0126-SM-48U1E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.964323 GSE135350_2_v_7_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-T2IS-0011-R6A-SM-32QP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.0085 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5341 Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 GSE120612_4_v_2_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null photosystem COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 3.34226 STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null PMC7146499__F2 PFOCR Pathway Figure Associations 2023 1.0 null Spondylometaphyseal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.078 t70-white-adipose_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.61279 KYSE-150 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WFG7-2426-SM-3GIL2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-XMD1-0011-R6A-SM-4AT5K GTEx Tissue Sample Gene Expression Profiles 1.0 1.63699 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-QDVJ-0726-SM-48U1W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE119498_0_v_10_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null CRCGN008_HEPG2_24H:D11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.4186 LS-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.588612 Perturb_6618_KO_NEUROD1_SRP388830 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.2967 H2722 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K10776934 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51586 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null Childhood Acute Lymphoblastic Leukemia DisGeNET Gene-Disease Associations 1.0 null PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE Rummagene Transcription Factor Associations 2026 1.0 null GTEX-TML8-1526-SM-4DXUX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-1297 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 degradation Phosphosite Textmining Biological Term Annotations 1.0 null GTEX-NPJ7-0011-R5a-SM-33HBK GTEx Tissue Sample Gene Expression Profiles 1.0 0.965674 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles 1.0 0.833326 GTEX-WVLH-0011-R5A-SM-3MJFW GTEx Tissue Sample Gene Expression Profiles 1.0 1.73908 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03459 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.986897 acute lymphoblastic leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070653 HOXA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1884 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.923339 BRD-K47983010_BX-795_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_II-Unnamed_1_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-885-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 hsa-miR-4639-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 GSE125219,GSE125221_5_v_2_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.77037 NCI-H1573 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03851 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.18 Lung adenocarcinoma_LUAD_TCGA-64-5775-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1182_KD_RUNX1_ERP128097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GSE116810_5_v_0_selinexor_human RummaGEO Drug Perturbation Signatures -1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null Parahippocampal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.786 PMC4070589-NIHMS573166-supplement-1.pdf-106-SPEN_SPEN Rummagene Transcription Factor Associations 2026 1.0 null Spondylometaphyseal dysplasia Sedaghatian type DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.452 SRF JASPAR Predicted Transcription Factor Targets 1.0 null GSE180800,GSE180801_0_v_5_tex10_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 placenta HPA Tissue Gene Expression Profiles -1.0 -0.931182 meningioma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.092862 Childhood Oligodendroglioma DisGeNET Gene-Disease Associations 1.0 null amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29798 GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_6339_KO_Des_SRP272249 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.14454 GSE94849_1_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null GSE214382,GSE214383_4_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null SNU201 DepMap CRISPR Gene Dependency 1.0 2.93482 GTEX-XYKS-0926-SM-4BRVG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 B-cell acute lymphoblastic leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.336 NCIH2172 CCLE Cell Line Gene CNV Profiles 1.0 1.95395 PMC5527282-ncomms16041-s3.xlsx-M_LPS_-_gene_signature-Supplementary_Data_2_Full_gene_list_of_M_LPS_-_signatures_as_defined_in_figure_3_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.449947 Perturb_14960_KO_Tfap4_SRP212619 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 14.2604 GRIK2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0072345 t-lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.222699 BRD-K43237307 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.69544 GSE199204,GSE211619_4_v_6_glutamine_human RummaGEO Drug Perturbation Signatures 1.0 null posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21468 PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_1_vs_3_NOT_Group_2_vs_3_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null NFATC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42591 mRNA_OTX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SERINC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01383 PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55D-0926-SM-3GAEU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Perturb_9829_KD_USP7_SRP256243 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.91225 GSE146612_1_v_0_amiodarone_human RummaGEO Drug Perturbation Signatures -1.0 null Memory Disorders CTD Gene-Disease Associations 1.0 1.49045 NCI-H1092 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K54233340_Dorsomorphin dihydrochloride_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7377 posterior part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22688 GSE126345_4_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null LOVO COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-548k TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 BRD-K81644801 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57761 GSE182680,GSE182683_0_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null basal ganglion TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE145915_5_v_4_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-TMMY-1526-SM-4DXST GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 leukocyte TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-S341-0726-SM-4AD5R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-S4UY-1226-SM-4AD51 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 striatum_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.4414 GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles 1.0 1.20465 BC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null Melancholic depression DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 GSE123943_4_v_0_sox1_human RummaGEO Gene Perturbation Signatures 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.59097 OVCAR8 BioGPS Cell Line Gene Expression Profiles -1.0 -1.24952 head TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 BRD-K43905345 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.10613 GSE94849_1_v_5_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null Dyspnea CTD Gene-Disease Associations 1.0 1.13586 pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.10387 Perturb_1177_KD_RUNX1_ERP128097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GSE254649_3_v_1_cstf2_human RummaGEO Gene Perturbation Signatures 1.0 null ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3727 SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4412 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE120595_5_v_4_arid2_mouse RummaGEO Gene Perturbation Signatures -1.0 null SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0407 HT-1376 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K79159743 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83381 GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CRCGN016_MCF10A.WT.HP_24H:P24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.5821 GTEX-WVLH-3026-SM-3MJG9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.873191 GTEX-T2IS-2226-SM-4DM65 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE164874_5_v_6_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41801 glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.07514 KARPAS-45 GDSC Cell Line Gene Expression Profiles 1.0 1.52615 HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09052 MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2306 GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.885579 BRD-K83475223 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.11623 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K11874023 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.69875 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14127 urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.0244 KARPAS-620 COSMIC Cell Line Gene Mutation Profiles 1.0 null Facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04574 leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055168 CL-40 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-4303 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Perturb_7991_KO_Dnmt3a_ERP107945 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.84071 Wt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 75.4901 cell part LOCATE Curated Protein Localization Annotations 1.0 null schistosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.134103 GSE182680,GSE182683_5_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null brain GTEx Tissue Gene Expression Profiles 1.0 1.69555 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 Hyperglycemia CTD Gene-Disease Associations 1.0 1.34314 Pons BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.3389 BRD-K71496240 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26297 PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_13480_KO_Bmal1_SRP260650 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.76565 BRD-K65320638 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63577 HPBALL CCLE Cell Line Gene CNV Profiles -1.0 -1.35515 GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles 1.0 0.882844 BRD-K03608799 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12892 BRD-K47555438 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1329 PPP2R5C LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00453259 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.40269 CRCGN008_HEPG2_24H:K02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -3.8713 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49827 Frontotemporal dementia and/or amyotrophic lateral sclerosis 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.078 GSE160817_5_v_8_slamf6_human RummaGEO Gene Perturbation Signatures 1.0 null CKS2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.003729 CCDC61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95608 RH-18 GDSC Cell Line Gene Expression Profiles 1.0 1.48798 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.55653 hsa-miR-4709-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GTEX-QCQG-1326-SM-48U24 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Wholebrain BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.16315 SARS-CoV MA15_Day1-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.70903 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.831955 GTEX-Q734-0008-SM-48U2I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K99749624_linifanib_BT20_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K49875070 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39852 myb_20142358_double_pos_tcrahomoneg_thymocytes_lof_mouse_gpl1261_gse19528 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.380296 GTEX-XV7Q-1426-SM-4BRWA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.961607 BRD-K85275903 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.61286 GTEX-P4PP-0008-SM-48TDV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 ethanol_mus musculus_gds3703 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hsa-miR-634 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 external carotid artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.43146 hsa-miR-3662 TargetScan Predicted Conserved microRNA Targets 1.0 0.248923 Perturb_4583_KO_Socs3_SRP074146 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.84543 PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K65752097 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.90369 gill filament TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.440274 BRD-K83049611 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08512 CRCGN008_HEPG2_24H:O03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.80445 GTEX-RWS6-0008-SM-47JYV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE151612_4_v_11_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null SLC25A37 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00633162 GSE129725_4_v_0_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_17437_KO_Usp7_SRP256242 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.941 Cognition Disorders CTD Gene-Disease Associations 1.0 1.5118 HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.883357 alveolar bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23604 debrisoquin LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.2271 BRD-K19724398_-666_VCAP_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null merozoite TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.331377 CRCGN015_MCF10A.TP53.M_24H:C08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.08785 GTEX-OHPN-0011-R5A-SM-2I5FF GTEx Tissue Sample Gene Expression Profiles 1.0 1.35366 superficial stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08317 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null endometrial stromal sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.246448 Thymic cortical epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.525 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-WFG8-0626-SM-3GILJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CUL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23198 GSE48812_8_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null GSE210580_0_v_1_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-N7MS-0011-R7a-SM-2HMKN GTEx Tissue Sample Gene Expression Profiles 1.0 1.42329 Lymphocytic leukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6121 PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-GeneID_FOXO3 Rummagene Transcription Factor Associations 2026 1.0 null Primary visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18434 layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06649 GTEX-S7SF-0926-SM-4AD4M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 adrenal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.10189 GTEX-S341-1226-SM-4AD5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 SARS-CoV MA15_Day1_None_GSE49262 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.943096 hsa-miR-4476 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GTEX-WEY5-0008-SM-4LMKC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-XV7Q-0826-SM-4BRV7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.934505 GSE179031_3_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSK3B_KD_GDS4305_181_human_MOLM-14 myeloid leukemia cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TC32 DepMap CRISPR Gene Dependency 1.0 3.11979 CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9469 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.22067 Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null General cognitive ability GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 Ventral globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.739 GSE174498,GSE174500_3_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null HCC2998 BioGPS Cell Line Gene Expression Profiles -1.0 -0.890814 BRD-K41185648 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16039 GTEX-XQ8I-1726-SM-4BOQB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 NALM6 CCLE Cell Line Gene Expression Profiles 1.0 1.70608 Tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.556 GTEX-R3RS-1326-SM-48FE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 abnormalities of the peripheral arteries GWASdb SNP-Phenotype Associations 1.0 0.241782 GSE135350_2_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-X261-0011-R6B-SM-4E3J8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05683 Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11779 SLR25 CCLE Cell Line Gene Expression Profiles -1.0 -1.57284 NR3C2-34362910-WISTARRAT-HIPPOCAMPUS ChEA Transcription Factor Targets 2022 1.0 null carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053765 VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36128 b800-850 antenna complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.14392 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OU-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QDVN-0426-SM-48TZ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 MEF2A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0053072 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7054 GTEX-RTLS-0526-SM-2TF64 GTEx Tissue Sample Gene Expression Profiles 1.0 0.864535 amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.232039 GSE147662_2_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null VZ in caudal cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2188 heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null GTEX-WZTO-2926-SM-3NM9I GTEx Tissue Sample Gene Expression Profiles 1.0 0.913039 GTEX-TKQ1-0008-SM-4DXSO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K97176469 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14507 lymph node disease GWASdb SNP-Disease Associations 1.0 0.775452 Ebolavirus(EBOV)_3day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.34047 Thymus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 3.934 CORO1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75024 CCDC80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06251 GSE123943_1_v_3_sox1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC12454715-13555_2025_1471_MOESM1_ESM.pdf-89-LEF1_LEF1 Rummagene Transcription Factor Associations 2026 1.0 null Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47938 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5625 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.0961 EVI2A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00620172 chronic fatigue syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.435651 CRCGN016_MCF10A.TP53.M_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.29169 BRD-K59002219 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30599 abnormality of the systemic arterial tree GWASdb SNP-Phenotype Associations 1.0 0.136651 Fibrosis CTD Gene-Disease Associations 1.0 1.48376 GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7584-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fungal infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050759 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.071 GTEX-QXCU-0008-SM-48FCH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null AZI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3671 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PGAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25147 NCIH810 CCLE Cell Line Gene CNV Profiles -1.0 -2.08944 peripheral blood mononuclear cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.24676 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null PF-382 GDSC Cell Line Gene Expression Profiles 1.0 1.64609 GTEX-RVPV-0011-R5A-SM-2TF69 GTEx Tissue Sample Gene Expression Profiles 1.0 1.39283 VZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39016 head kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.329727 chromosomal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.207451 posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02373 PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null Brain stem TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.299 cell periphery COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.311851 neurological GAD High Level Gene-Disease Associations 1.0 0.293278 BRD-K76960042 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00389 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.74021 CRCGN015_MCF10A.TP53.M_24H:L09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.7772 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6355 GSE206516,GSE206518_1_v_4_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9989 NEO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07556 GTEX-O5YT-0126-SM-48TBW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 NALM1 CCLE Cell Line Gene Expression Profiles 1.0 1.36885 rhabdoid meningioma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.894179 intermediate stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03042 CD33 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00598304 SPI1 ENCODE Transcription Factor Targets 1.0 null GSE89767_6_v_5_cebpa_mouse RummaGEO Gene Perturbation Signatures 1.0 null Hemoptysis DisGeNET Gene-Phenotype Associations 1.0 null nucleus lentiformis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.393442 hsa-miR-659 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 kawasaki disease GWASdb SNP-Disease Associations 1.0 0.775452 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.97051 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Coronary Arteriosclerosis DisGeNET Gene-Disease Associations 1.0 null nectary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.194369 reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045834 GSE101112_0_v_2_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-VUSH-0008-SM-47JWK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 photoreceptor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.181338 GTEX-QCQG-0626-SM-48U21 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE126127_5_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-133a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GTEX-WWYW-0011-R11A-SM-3NB38 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03171 substantia nigra, pars compacta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10475 GTEX-WHSE-0011-R6A-SM-3P5ZP GTEx Tissue Sample Gene Expression Profiles 1.0 1.88478 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5273 basal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.745864 GTEX-V1D1-0226-SM-4JBHG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CHST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65147 layer 3 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48536 nectar TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.206715 EFM19 DepMap CRISPR Gene Dependency 1.0 2.35685 SUPT7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65541 GSE146612_1_v_3_amiodarone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Spreading_targets_gene_names_117_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09423 Vestibular nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40386 intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.127355 stoma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.72733 GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 0.992526 GTEX-XQ8I-0326-SM-4BOPN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-381 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GTEX-WWYW-0011-R7A-SM-3NB3H GTEx Tissue Sample Gene Expression Profiles 1.0 1.42315 GATA1 JASPAR Predicted Transcription Factor Targets 1.0 null Perturb_2949_KD_Msi2_DRP004738 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -13.1581 GTEX-XV7Q-0226-SM-4BRVL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-QLQ7-1726-SM-2S1QQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.824074 imatinib_homo sapiens_gpl96_gds3044 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null root cap TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.525166 BRD-K53936012 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40271 GTEX-T5JC-0001-SM-3NMAK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 DEPDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59472 CP66-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null dorsolateral part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74027 SP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78782 caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.58741 ZIC3-20872845-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.97829 GTEX-XBED-0526-SM-47JY3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC3214047-pone.0027384.s003.xlsx-nr_listofpeakinhuman-TableS2_List_of_direct_IRF8_targets_in_human_GC_B_cell_lines_IRF8 Rummagene Transcription Factor Associations 2026 1.0 null striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.19796 GSE240896,GSE240899_10_v_4_ccnt1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE153836_11_v_2_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.12768 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.32418 Perturb_1020_KO_Apoe/Apoa1_SRP318735 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.12275 Perturb_2950_KD_Myog_DRP004738 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.3869 GSE120612_7_v_2_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-K63984483 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02471 GSE48812_4_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.51186 METTL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84647 mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-WWYW-0011-R5A-SM-3NB3E GTEx Tissue Sample Gene Expression Profiles 1.0 1.71406 Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A894-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5263239-mmc2.xls-KOPN-8_-_MLL-ENL-Spreading_targets_gene_names_108_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.47394 mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10003 Perturb_16878_KO_Trrap_SRP198540 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.58253 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LE-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4431731-pgen.1005211.s002.xlsx-ERG_TRISOMY-Unnamed_2_ERG Rummagene Transcription Factor Associations 2026 1.0 null BRD-K63068307_ZSTK-474_SKBR3_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null flexor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.949531 GSE233647_4_v_6_docetaxel_human RummaGEO Drug Perturbation Signatures -1.0 null inflammatory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214202 GTEX-QLQ7-0008-SM-447AW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-4719 TargetScan Predicted Conserved microRNA Targets 1.0 0.265648 NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.843306 Combined Immunodeficiency DisGeNET Gene-Disease Associations 1.0 null other source TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.625869 BRD-K18176829 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24495 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.63394 rostral putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.981983 Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.16967 GSE92457_7_v_8_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-S4P3-0426-SM-4AD56 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.956399 BRD-K61520618 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19578 COLO849 CCLE Cell Line Gene CNV Profiles 1.0 1.5979 Reperfusion Injury CTD Gene-Disease Associations 1.0 1.07589 calcific tendinitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.582773 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50505 GSE182680,GSE182683_10_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null brain HPA Tissue Gene Expression Profiles 1.0 1.69733 UBC Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-3915 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 type ii diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.480806 CRCGN017_MCF10A.WT.HP_24H:A16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.6476 Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE153757,GSE153758_1_v_3_ftsj1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-SNMC-0626-SM-4DM6H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE137914_4_v_1_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K94582731 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27692 substance-related disorder GWASdb SNP-Disease Associations 1.0 0.191344 BRD-K78939372 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17125 GTEX-T5JW-0726-SM-4DM6D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.35252 GTEX-XBED-0008-SM-47JWO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-4725-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GSE73561,GSE73563_0_v_1_mef2c_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_2947_KD_Ddx17_DRP004738 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.6213 PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-SKOR2-gene_SKOR2 Rummagene Transcription Factor Associations 2026 1.0 null lymphoid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.48087 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.883513 GTEX-P44H-0008-SM-48TDW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1757_KO_p300_SRP250516 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.42267 hsa-miR-579 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GSE159678_4_v_7_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PW2O-0826-SM-48TC5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.79091 enzyme-inhibitors Phosphosite Textmining Biological Term Annotations 1.0 null GTEX-XUJ4-0526-SM-4BOON GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 AKR1C4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00627831 BRD-K39438085 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16708 H2AFZ ENCODE Transcription Factor Targets 1.0 null midbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.217139 GSE145915_3_v_4_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PSDG-1326-SM-48TD2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE197117_0_v_1_kdm6b_mouse RummaGEO Gene Perturbation Signatures -1.0 null brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.264011 GTEX-R53T-0008-SM-48FEW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 scale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.664368 CRCGN015_MCF10A.TP53.M_24H:K20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0298 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF605 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18337 Perturb_6136_KO_Nox2_SRP155219 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.6705 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null coronary artery disease GWASdb SNP-Phenotype Associations 1.0 0.672779 hsa-miR-1260b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE145915_3_v_2_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X4XX-3026-SM-3NMB2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.839855 19549311-SuppTable2-MMLandPhenotype GeneSigDB Published Gene Signatures 1.0 null ZMAT3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00506278 inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02478 Ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.593912 brain_3b HPA Tissue Sample Gene Expression Profiles 1.0 1.44365 GTEX-S7SF-0826-SM-4AD4W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-QDVJ-1126-SM-48U1U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 leg TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.456828 fluoxetine_mus musculus_gds2803 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K50677542 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72737 GSE210101,GSE210114_1_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_15717_OE_Ctcf_SRP173291 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.20425 H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.65307 GTEX-OHPL-1626-SM-2HMIR GTEx Tissue Sample Gene Expression Profiles 1.0 0.96125 BRD-K63998843 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09923 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.972358 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-2626-SM-32PMQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.842957 PMC7146499__F2 PFOCR Pathway Figure Associations 2024 1.0 null intermediate stratum of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10714 plicamycin_homo sapiens_gpl570_gse25127 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null renal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.508808 foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.178007 GTEX-SE5C-0926-SM-4BRUF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 dental follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.512171 ZSWIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41537 photosystem ii reaction center COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.33902 leaf lamina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.648938 NCKAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98288 OVSAHO CCLE Cell Line Gene CNV Profiles -1.0 -1.95982 GTEX-WL46-0011-R6A-SM-3LK6X GTEx Tissue Sample Gene Expression Profiles 1.0 1.45333 molaris TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.868107 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 2.07902 plant reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.345928 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21622 GSE174418,GSE174421_0_v_1_mettl5_mouse RummaGEO Gene Perturbation Signatures 1.0 null nephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.074143 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S3XE-0426-SM-3K2AC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-U3ZN-1726-SM-4DXUQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 SF539 BioGPS Cell Line Gene Expression Profiles -1.0 -1.2132 GTEX-V1D1-0526-SM-4JBGW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null NR4A2-19515692-MN9D-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mRNA_FOXJ2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.544411 SMARCD1-25818293-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_4151_KO_Csmd3_SRP343147 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.66717 NCIH1694 CCLE Cell Line Gene CNV Profiles -1.0 -1.8082 BRD-K44422244 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01387 Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53203 BRD-K76904668 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57557 GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 SNU449 CCLE Cell Line Gene CNV Profiles -1.0 -2.16661 OVSAHO CCLE Cell Line Gene Expression Profiles -1.0 -2.15665 GSE165308_1_v_0_gfi1_human RummaGEO Gene Perturbation Signatures -1.0 null MHHES1 CCLE Cell Line Gene CNV Profiles -1.0 -1.49061 P-19 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.659 SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4781 Nucleus preopticus medialis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.771 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE126345_0_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE109530,GSE109531_1_v_0_hdac3_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K96198015 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19593 nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046155 PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR1-List_of_differentially_expressed_genes_in_AR11_vs_AR1_Negative_value_means_down-regulation_in_AR11_TCF20 Rummagene Transcription Factor Associations 2026 1.0 null MAPKAPK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6722 JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null Pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.461 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40791 SUPB15 CCLE Cell Line Gene Expression Profiles 1.0 1.87946 GSE175787_8_v_10_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_8505_KO_Hdac11_SRP253771 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.80531 FGFR3_knockdown_174_GSE41035 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.06705 Perturb_6616_KO_NEUROD1_SRP388830 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.66409 BRD-K50462936 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30267 GTEX-SUCS-0926-SM-4DM4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE213588_9_v_1_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-A60245366_AS-601245_HCC515_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-XQ3S-0008-SM-4GIDZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 ASCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66053 BRD-K61925563 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04136 GSE48812_2_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null mantle zone of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16543 ZNF226 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35431 PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3 Rummagene Transcription Factor Associations 2026 1.0 null SUZ12-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null NR4A2 ChEA Transcription Factor Targets 1.0 null PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null bodies Phosphosite Textmining Biological Term Annotations 1.0 null MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.888398 NCI-H1793 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE150665,GSE150667_1_v_8_mysm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QDT8-0011-R2A-SM-32PKQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.826428 CAL 27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18568 TMEM132B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79562 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-0626-SM-4DM5F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 abnormal nervous system physiology MPO Gene-Phenotype Associations 1.0 null thylakoid part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 3.25332 protein-phosphatase-1 Phosphosite Textmining Biological Term Annotations 1.0 null Lung Diseases CTD Gene-Disease Associations 1.0 1.1136 response to stress GO Biological Process Annotations 2015 1.0 null PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA Rummagene Transcription Factor Associations 2026 1.0 null Hypothalamus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 hsa-miR-944 TargetScan Predicted Conserved microRNA Targets 1.0 0.454769 GTEX-U8T8-0008-SM-4DXSP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.06633 GTEX-U4B1-0326-SM-3DB8K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-OXRL-0626-SM-3NM9C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-S33H-0626-SM-2XCBJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-PW2O-0008-SM-48TEB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 alpha-motoneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.879089 BRD-K97370549 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0591 bronchial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.338341 biceps brachii TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.705173 av3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.808 cerebellar cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.931344 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.889124 NCI-H2803 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.898972 nicotine dependence GWASdb SNP-Disease Associations 1.0 1.15334 Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48557 maternal diabetes GWASdb SNP-Phenotype Associations 1.0 0.634615 BRD-K03624299 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00517 BRD-K80073743 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.247 pka Phosphosite Textmining Biological Term Annotations 1.0 null leaf disc TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.310783 18223198-Table5 GeneSigDB Published Gene Signatures 1.0 null GSE210580_5_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-X88G-0126-SM-47JZ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62112 BRD-K92571446_WZ-3105_HCC515_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CRCGN017_MCF10A.TP53.M_24H:E01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.28065 GTEX-POMQ-2026-SM-2S1OD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 tooth germ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.138399 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null syndromic GeneRIF Biological Term Annotations 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.05516 GSE218060_5_v_6_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K76694128_DCC-2036_A375_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K21841771 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.99076 GSE115542_2_v_0_digoxin_human RummaGEO Drug Perturbation Signatures 1.0 null HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8735 light-harvesting complex, peripheral complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.14392 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null CAMA1 DepMap CRISPR Gene Dependency 1.0 2.5776 binding GO Molecular Function Annotations 2015 1.0 null posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68107 SMAD2/3-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.889124 GSE115363_2_v_0_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles 1.0 0.825237 BRD-K43872193 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28321 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T6MO-0526-SM-4DM6R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 SW982 DepMap CRISPR Gene Dependency 1.0 2.09493 Multilymphoid progenitor cell_Umbilical cord blood_Human CellMarker Gene-Cell Type Associations 1.0 null r1 part of the 'mesencephalic' trigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01411 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.51108 GSE106661,GSE106665_2_v_3_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null GATA1-19941827-MEL-MOUSE ChEA Transcription Factor Targets 2022 1.0 null S1PR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66414 Pancreatic Neoplasms CTD Gene-Disease Associations 1.0 1.2415 chronic lymphocytic leukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null VRK2 Kinase Library Serine Threonine Kinome Atlas 1.0 null BRD-K74712962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47434 CRCGN016_MCF10A.TP53.M_24H:D20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.08709 GTEX-XK95-1026-SM-4GIDV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 striatal Phosphosite Textmining Biological Term Annotations 1.0 null BRD-K50149147 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31303 salivary gland HPA Tissue Protein Expression Profiles 1.0 1.25705 gastroesophageal junction TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.222938 GSE182680,GSE182683_5_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.702308 GTEX-U3ZM-0126-SM-3DB8M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-4276 TargetScan Predicted Conserved microRNA Targets 1.0 0.205675 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.88797 sporozoite TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.623043 IST-MEL1 COSMIC Cell Line Gene Mutation Profiles 1.0 null body wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.966793 GTEX-Q2AG-0011-R10A-SM-2HMLA GTEx Tissue Sample Gene Expression Profiles 1.0 0.916287 IMPA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17728 docebenone LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18519 NEIL1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00512866 aorta TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.24052 GSE140092_0_v_1_socs3_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null pineal_night BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.904629 Pain CTD Gene-Disease Associations 1.0 1.36763 GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.01047 MROH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87035 cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.233731 GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9644 suppurative periapical periodontitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.856905 Liver Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.06698 GSE150665,GSE150667_4_v_5_mysm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_15718_OE|KD_Ctcf|Smarca5_SRP173291 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.76157 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0815 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3320-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hamstring muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.252261 GSE89767_7_v_5_cebpa_mouse RummaGEO Gene Perturbation Signatures 1.0 null U-118-MG COSMIC Cell Line Gene Mutation Profiles 1.0 null Primary visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42735 Ganglion TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.016 GTEX-R55E-0011-R11A-SM-2TC6I GTEx Tissue Sample Gene Expression Profiles 1.0 1.13124 CRCGN016_MCF10A.WT.HP_24H:M01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.98442 GTEX-P44H-0011-R5A-SM-2XCEX GTEx Tissue Sample Gene Expression Profiles 1.0 2.10676 Perturb_4199_KO_Fmr1_SRP075646 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.77051 GSE182680,GSE182683_7_v_12_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null Worry too long after an embarrassing experience GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.2 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4357 NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6492 VMRCLCD CCLE Cell Line Gene CNV Profiles -1.0 -1.52941 Combined oxidative phosphorylation deficiency 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.046 GSE96777,GSE96778_1_v_0_zbtb4_human RummaGEO Gene Perturbation Signatures 1.0 null HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09052 superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70222 BRD-K55311609 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06108 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34484 clasp2 GeneRIF Biological Term Annotations 1.0 null Parkinson's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.389 Perturb_15359_KO_Tfap4_SRP212619 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.26028 GTEX-X585-0011-R5A-SM-46MVI GTEx Tissue Sample Gene Expression Profiles 1.0 1.50092 GTEX-N7MS-0011-R11A-SM-2HMJS GTEx Tissue Sample Gene Expression Profiles 1.0 1.08055 Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95484 Human - Motor Cortex - Cross-Species Cluster - Sncg+ GABAergic neuron_4 HuBMAP Azimuth Cell Type Annotations 1.0 null urinary tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.720345 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.889124 ciliary basal body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.206082 nuclear chromosome part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04932 17429429-Table4 GeneSigDB Published Gene Signatures 1.0 null BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05827 hsa-miR-2110 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 eye and adnexa disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.196779 r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05507 Seizures CTD Gene-Disease Associations 1.0 1.07411 GSE160817_7_v_8_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.399 GTEX-P4PQ-0008-SM-48TDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 cuneiform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.927114 kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.622639 CEP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61051 captopril_mus musculus_gpl1261_gds3683 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-QDT8-0626-SM-48TYW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.435 BMI1-23680149-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_14299_KO_Mef2c_SRP057560 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.8313 GTEX-P4QR-0008-SM-48TE2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-26b TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.749579 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.965678 GSE153836_14_v_5_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 0.975052 GTEX-V955-2526-SM-4JBJG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.30447 Roifman-Chitayat Syndrome DisGeNET Gene-Disease Associations 1.0 null GTEX-RU72-0011-R6A-SM-2TF71 GTEx Tissue Sample Gene Expression Profiles 1.0 1.55229 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34796 Thrombin-activatable fibrinolysis inhibitor activation peptide GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.604576 COLO-783 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PWO3-0011-R6A-SM-2I5F3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24548 GSE123943_2_v_0_sox1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QCQG-0426-SM-48U29 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-XV7Q-1126-SM-4BRVS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Leukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-SE5C-2126-SM-4BRUJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 ARID3A JASPAR Predicted Transcription Factor Targets 1.0 null granulation tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213833 Fetalbrain BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.959752 lymphoid tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 retinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.056608 GTEX-X585-0011-R6A-SM-46MVJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.78136 GSE145171_0_v_1_prox1_human RummaGEO Gene Perturbation Signatures -1.0 null Diagonal band TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.558 GCM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9326 hsa-miR-1322 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Perturb_69_KD_SMARCB1_SRP280151 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-T8EM-0526-SM-4DM64 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Exoskeleton TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.633 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75025 GTEX-V1D1-1926-SM-4JBGX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 LRRK2_mutant_32_GDS4400 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.39988 KRAS.PROSTATE_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null Chest Pain CTD Gene-Disease Associations 1.0 1.01249 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6208 Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CRCGN015_MCF10A_48H:A07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.19646 epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.758673 neck TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.270561 Perturb_933_KD_TLX1_SRP132967 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.51545 intermediate stratum of r5Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41622 methylphenidate_mus musculus_gpl11180_gse33619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_15611_KO_Nampt_SRP065603 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.1191 BRD-K42971210 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32532 nerve-tissue-proteins Phosphosite Textmining Biological Term Annotations 1.0 null PVR LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00603515 PMC3245917-supp_gkr685_nar-01129-x-2011-File015.xls-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XLM4-0011-R7A-SM-4AT5L GTEx Tissue Sample Gene Expression Profiles 1.0 1.76555 H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null jaw TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.24208 GTEX-QLQ7-0826-SM-447B3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-XQ3S-1526-SM-4BOOC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 cellular response to stress GO Biological Process Annotations 2015 1.0 null ID1_01_118 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60646 CP50-MEL-B COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K76485827 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00409 BRD-K33702515 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05542 ACSM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5794 PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-Unnamed_1_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC Rummagene Transcription Factor Associations 2026 1.0 null locus coeruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05745 PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K55479099 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.12608 Heart Diseases CTD Gene-Disease Associations 1.0 1.19246 GSE206516,GSE206518_3_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures 1.0 null schizozoite TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.880358 parasitic protozoa infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.057138 GTEX-QEL4-0326-SM-3GAE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.843306 midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.18192 GSE94849_3_v_2_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4768-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.95017 BRD-A52650764_Ingenol 3, 20-dibenzoate_SNUC4_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null von hippel-lindau disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.774932 AP-4 MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K51791049 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26295 Perturb_4584_KO_Socs3_SRP099234 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.84543 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.956662 cerebral gray matter TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.419242 nuclear part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.398199 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A185-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4536 TargetScan Predicted Conserved microRNA Targets 1.0 0.419947 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.827473 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.43274 uterus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057535 GTEX-OXRP-0926-SM-48TC1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-XYKS-2726-SM-4E3IC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 IGFBPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6322 BRD-K64347765 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05185 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.07502 hsa-miR-548p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.944507 CRCGN016_MCF10A.TP53.M_24H:O09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.72698 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3362-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWS6-1026-SM-47JXD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 intermediate stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80083 Depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.253 GSE171179,GSE171181_0_v_1_e7107_human RummaGEO Drug Perturbation Signatures -1.0 null PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.00763 body of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.77232 LPA LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00782538 GTEX-XQ8I-0426-SM-4BOPO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 limb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.735147 superficial stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02289 Fetal Growth Retardation CTD Gene-Disease Associations 1.0 1.68337 GTEX-QCQG-0126-SM-48U27 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GRANTA-519 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26776 needle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.336336 GSE236262_0_v_3_trim28_mouse RummaGEO Gene Perturbation Signatures 1.0 null Major Depressive Disorder DisGeNET Gene-Disease Associations 1.0 null viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.265494 GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.10724 ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9318 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 NFKBID CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94591 putamen, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74354 GTEX-RNOR-2326-SM-2TF4I GTEx Tissue Sample Gene Expression Profiles 1.0 0.9335 ESO51 COSMIC Cell Line Gene Mutation Profiles 1.0 null protozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.282483 Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25468 GATAD2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84167 PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WZTO-0011-R11A-SM-4E3K9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06831 BRD-K58472651 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05388 Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.076356 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K86693846 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10703 BDCA4+_DentriticCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01434 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.948269 GTEX-T5JC-0011-R10A-SM-32PM2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.935844 BRD-K04488512 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04857 GSE216273,GSE216292_0_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-S32W-0826-SM-4AD5Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE151612_4_v_2_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null cancellous bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.243294 CRCGN016_MCF10A.WT.HP_24H:P10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.72381 hsa-miR-668 TargetScan Predicted Conserved microRNA Targets 1.0 0.241055 GSE146982_3_v_2_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null thigh TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.124828 MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null hsa-miR-634 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.9163 GSE210101,GSE210114_8_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.259124 TENM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30462 Huntington's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.469 plumule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.720345 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.96341 GSTM4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00760315 GTEX-QDT8-0008-SM-48U2F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.07 nucleus accumbens, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86377 lingual gyrus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10179 GTEX-T2IS-0011-R11A-SM-32QPC GTEx Tissue Sample Gene Expression Profiles 1.0 1.12049 diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.370688 MYC_KD_GSE22139_685_human_medulloblastoma GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Tal-1beta:E47 MotifMap Predicted Transcription Factor Targets 1.0 null cerebellar nuclei of CbV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80562 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5018 RCH-ACV COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 1.04736 H3K27me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null chlorosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.00547 periapical granuloma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.21738 hsa-miR-3163 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 HOXC11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9092 BRD-K53992608 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33717 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.82634 GSE193588_3_v_2_pax3_mouse RummaGEO Gene Perturbation Signatures -1.0 null FCN3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00558661 GSE94849_3_v_4_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.621804 GTEX-SN8G-0326-SM-32PLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.13113 Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39083 hsa-miR-4287 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GTEX-WVLH-2926-SM-3MJG5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.976653 GTEX-NFK9-0008-SM-4E3JE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.65543 external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02173 GSE182680,GSE182683_5_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null HSPBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8463 epithelioid sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.368888 blood TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE162590_1_v_0_gsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ehrlichiosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.690694 GTEX-NL4W-0011-R11A-SM-2I3DW GTEx Tissue Sample Gene Expression Profiles 1.0 1.05203 cranium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.987162 SMAD3-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-X4XX-1126-SM-3NMBY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-V1D1-0008-SM-4JBIJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Diarrhea CTD Gene-Disease Associations 1.0 1.08478 BRD-A52510783 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15835 Posterolateral visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08197 hsa-miR-331-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 EZH2 ENCODE Transcription Factor Targets 1.0 null podocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.230931 CRCGN016_MCF10A.WT.HP_24H:H17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.26891 parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13235 Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.052 Perturb_13298_OE_Pik3ca_SRP173204 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.23307 GSE210101,GSE210114_5_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null GSE228263_0_v_1_elesclomol_human RummaGEO Drug Perturbation Signatures 1.0 null SIRT1_Deficiency_GDS4895_316_mouse_Brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67117 MPL LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0066162 hsa-miR-4526 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 K562 BioGPS Cell Line Gene Expression Profiles 1.0 1.29323 Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Immune system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 3.934 r6 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1932 GTEX-TMMY-0008-SM-4DXU3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GPA33 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00444138 GSE169152_5_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null STK17B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00582744 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7784 hippocampus (hippocampal formation)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.967429 H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4437 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-SKOR2-gene_SKOR2 Rummagene Transcription Factor Associations 2026 1.0 null cyclophosphamide_rattus norvegicus_gpl1355_gse48407 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE149769_1_v_0_nlrp12_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-GSX1_GSX1 Rummagene Transcription Factor Associations 2026 1.0 null KYSE-140 COSMIC Cell Line Gene Mutation Profiles 1.0 null forelimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.674135 TBRG4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00540891 SW1271 CCLE Cell Line Gene CNV Profiles 1.0 1.39761 GSE182680,GSE182683_10_v_12_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null OAZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55022 Copula pyramidis, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71862 GTEX-P78B-0008-SM-48TE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Metencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.166 Motor neuron disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.351 KE-37 GDSC Cell Line Gene Expression Profiles 1.0 1.4818 BRD-K98856654 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4708 GSE233647_2_v_3_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null Serum Gamma-Glutamyl Transferase Measurement DisGeNET Gene-Phenotype Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4945-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P31-FUJ COSMIC Cell Line Gene Mutation Profiles 1.0 null ventral nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.240826 BRD-A14331394 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18251 Acute myeloid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.9119 KLF15_KO_GDS4780_509_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-U3ZN-1226-SM-4DXUD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.895904 Sarcoma_SARC_TCGA-DX-A48K-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null craniofacial region TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.984991 lymphocytic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061789 ChIP_SUZ12_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-KLF5_targets-target_gene_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K55940699 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15263 GSE182680,GSE182683_10_v_9_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XXEK-0626-SM-4BRWE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K04269696 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39053 GTEX-XOTO-0011-R3A-SM-4B64W GTEx Tissue Sample Gene Expression Profiles 1.0 0.835202 r1 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03218 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null SKOV3 DepMap CRISPR Gene Dependency 1.0 2.19502 Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 GSE48812_4_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null spindle cell hemangioma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.636315 Nucleus y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08413 chloroplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.530028 Myocarditis CTD Gene-Disease Associations 1.0 1.0784 CA9-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nucleus accumbens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04307 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12566 spinal cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.460305 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.74003 H3K27me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Nodulus (X), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9672 BRD-K39561340 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43416 GSE160817_0_v_8_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null LUDLU1 DepMap CRISPR Gene Dependency 1.0 2.00254 nucleus accumbens, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74642 uterine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.104986 CTCF ENCODE Transcription Factor Targets 1.0 null PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XYKS-0526-SM-4BRW2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-4685-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 WM88 CCLE Cell Line Gene CNV Profiles 1.0 2.51208 MOLT-4 GDSC Cell Line Gene Expression Profiles 1.0 1.52593 skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles 1.0 1.30119 connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.916496 mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.446422 Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.5821 Body Mass Index DisGeNET Gene-Phenotype Associations 1.0 null GSE133213_6_v_15_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE234637_2_v_0_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-448 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles 1.0 2.10917 BRD-K04968881 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51954 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_DN3_ChIP-seq_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.88067 GTEX-OHPN-0011-R7A-SM-2I5FI GTEx Tissue Sample Gene Expression Profiles 1.0 1.21896 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null levetiracetam_rattus norvegicus_gpl1355_frontal cortex_gds1864 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null tendinitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.142064 CRCGN016_MCF10A.TP53.M_24H:C07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.2966 GTEX-SIU7-0526-SM-3NM8I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Age-related cognitive decline (language) (slope of z-scores) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.652288 GSE147210_2_v_5_kmt2d_mouse RummaGEO Gene Perturbation Signatures 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Interposed nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36822 GSE210101,GSE210114_2_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null PMC8571097-41588_2021_941_MOESM3_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_List_of_KMT2A_fusion_oncoprotein_target_genes_in_each_sample_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13514 viral replication complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.330966 H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.28346 Neurociticism GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7578 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null U118MG DepMap CRISPR Gene Dependency 1.0 2.68806 BRD-K67270926 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07376 medial habenular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02951 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33091 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5635-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.694 GSE88819_11_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 2 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5569 PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG Rummagene Transcription Factor Associations 2026 1.0 null glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.394661 BRD-K49328571_dasatinib_BT20_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-UTHO-0011-R6A-SM-3GIJW GTEx Tissue Sample Gene Expression Profiles 1.0 1.98995 blood plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.358919 GTEX-T6MN-2526-SM-32PMN GTEx Tissue Sample Gene Expression Profiles 1.0 1.01628 hsa-miR-939 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 C8orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77473 GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 NPAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47334 SAA4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00805917 SUPT1 CCLE Cell Line Gene Expression Profiles 1.0 1.3593 H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE195559_8_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QLQW-0726-SM-447AA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-TKQ2-0008-SM-4DM5L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2285 cyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.05193 ESRRB LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00535223 GTEX-T6MN-0011-R6A-SM-32QP8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.36119 hypnozoite TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.880358 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-T2IS-0008-SM-4DM75 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PKCTHETA-26484144-CHIP-SEQ-BREAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21784 leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.639214 TP53INP2_OE_GDS5054_276_mouse_SKM-Tg - Skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Liver Diseases CTD Gene-Disease Associations 1.0 1.23424 A172 BioGPS Cell Line Gene Expression Profiles -1.0 -1.38581 incisor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.217346 KCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49919 GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-PSDG-0326-SM-48TCP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 neurons Phosphosite Textmining Biological Term Annotations 1.0 null Thorax TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 3.934 Nerve Degeneration CTD Gene-Disease Associations 1.0 1.31178 GSE152699,GSE152723_3_v_1_vemurafenib_human RummaGEO Drug Perturbation Signatures -1.0 null E2F4 ChEA Transcription Factor Targets 1.0 null Brain Edema CTD Gene-Disease Associations 1.0 1.41368 GSE142684_2_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QVJO-0126-SM-3GIK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0227 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4903-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.564362 CBP-20019798-JUKART-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles 1.0 1.11714 upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72243 GTEX-Q734-1426-SM-48TZQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 chromosome segregation-directing complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.670725 BRD-K31034311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1096 striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.61559 Embryonic cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.59 clathrin-sculpted gamma-aminobutyric acid transport vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.147 PMC5263239-mmc2.xls-MLL-AF4_Patient_Cells-Spreading_targets_gene_names_94_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.928618 Alstrom syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.1 GSE119498_0_v_7_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIRT1_KO_GSE28790_47_mouse_brain (3 mo) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null General factor of neuroticism GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0 GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05694 cognitive performance GAD Gene-Disease Associations 1.0 null BRD-A60245366_AS-601245_BT20_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.691268 intermediate stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49902 striatum_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.34987 GTEX-RN64-1026-SM-48FDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 neostriatum TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 metacercaria TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.52635 Mouse - Motor Cortex - Cross-Species Cluster - Sst+ GABAergic neuron_7 HuBMAP Azimuth Cell Type Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 hsa-miR-300 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 RING1B-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K46790201 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32213 GSE183413_0_v_2_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.051 catalytic complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.048546 BMI1 ChEA Transcription Factor Targets 1.0 null REH COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endometrial cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.124299 hsa-miR-3910 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GTEX-XOTO-0011-R7B-SM-4B64R GTEx Tissue Sample Gene Expression Profiles 1.0 1.53805 GSE149880_0_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null isthmic vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7285 periventricular stratum of r5Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38073 GTEX-PW2O-1926-SM-2S1OB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K20809650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82999 GSE48812_2_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9573 eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.200006 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.883357 BRD-A19037878_trichostatin A_PC3_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Cardiomegaly CTD Gene-Disease Associations 1.0 1.18159 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.960977 LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.547297 GSE182680,GSE182683_5_v_11_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.64791 GSE195559_0_v_9_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.845425 GTEX-NPJ7-0011-R6a-SM-2I3G7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.88795 hsa-miR-4799-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GTEX-T8EM-1826-SM-4DM7F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-P4QS-0008-SM-48TDY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 ES-I3 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.91538 Muscle-slow muscle cell Tabula Sapiens Gene-Cell Associations 1.0 0.227822 urinary system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.635976 GSE182179_5_v_3_kdsr_human RummaGEO Gene Perturbation Signatures -1.0 null T84 COSMIC Cell Line Gene CNV Profiles 1.0 2.14116 GSE115363_3_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null cAMP-dependent protein kinase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.333 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.33908 19244127-Table2 GeneSigDB Published Gene Signatures 1.0 null GTEX-S7SF-0526-SM-3K2BC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CRCGN015_MCF10A.WT.HP_24H:H13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.74617 MHH-NB-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null mast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.335233 Organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.502 GSE164874_5_v_9_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null intestinal schistosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.373698 SALL4-18804426-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-N7MS-0011-R6a-SM-2HMJ4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.2417 retinal cone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.226411 respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.896895 BRD-K90660470 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30188 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3031 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32273 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05827 hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09195 GSE219195_4_v_2_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null GSE175787_8_v_0_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7834 r5 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38073 GTEX-OIZH-0226-SM-2YUMH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 CRCGN015_MCF10A.WT.HP_24H:F16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.3779 GSE202434,GSE202438_7_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null striatum_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.37938 ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null EBF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46144 Lung adenocarcinoma_LUAD_TCGA-67-6216-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TML8-1826-SM-32QOR GTEx Tissue Sample Gene Expression Profiles 1.0 0.941405 GTEX-TMMY-1626-SM-4DXTY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-T5JC-0011-R11A-SM-32PMB GTEx Tissue Sample Gene Expression Profiles 1.0 1.16555 GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.09844 GTEX-X88G-0004-SM-47JZ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9170110-pgen.1010161.s047.xlsx-DBP_DEP-nearestGene_DBP Rummagene Transcription Factor Associations 2026 1.0 null testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.86038 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D6-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.217554 H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MT-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Myocardial Infarction DisGeNET Gene-Disease Associations 1.0 null Nodulus (X), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20803 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7589 VNN1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00520642 endometrial stromal tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.243995 GTEX-RM2N-0326-SM-48FD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37294 GTEX-T6MO-0126-SM-4DM6X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S7PM-0011-R5A-SM-3NM8G GTEx Tissue Sample Gene Expression Profiles 1.0 0.847898 GTEX-PWOO-0008-SM-48TDU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 leukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.882575 olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38913 stria terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.243918 femoral artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.475034 Substance-Related Disorders CTD Gene-Disease Associations 1.0 1.17827 GTEX-R55D-0326-SM-48FES GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GTEX-O5YT-1626-SM-32PK6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.991486 NCI-H2373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10703 nephron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.219264 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.87793 GTEX-XXEK-1226-SM-4BRUY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 GSE135350_2_v_5_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K91620436 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11176 BRD-K05304510 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.91374 ROS50 DepMap CRISPR Gene Dependency 1.0 4.90551 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal channel response MGI Mouse Phenotype Associations 2023 1.0 null GSE126402_2_v_7_tal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.18986 GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 0.91806 Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.532 GSE203362_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-S4P3-0926-SM-4AD54 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 BRD-K32477623 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32717 FXR MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K25304254 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.80401 hsa-miR-3974 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.971505 GSE94814_1_v_0_reck_mouse RummaGEO Gene Perturbation Signatures 1.0 null ARHGAP23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97628 PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF Rummagene Transcription Factor Associations 2026 1.0 null CCRF-CEM GDSC Cell Line Gene Expression Profiles 1.0 1.74106 RDH12 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00527488 Perturb_16113_KO_Actl6a_SRP326668 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.60791 ZIC3 ChEA Transcription Factor Targets 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.48 Photoreceptor Degeneration DisGeNET Gene-Disease Associations 1.0 null GTEX-V955-0326-SM-4JBGV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 Cerebral lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 JUND JASPAR Predicted Transcription Factor Targets 1.0 null RAD51 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00684476 BRD-K81418486_vorinostat_CORL23_6.0_h_11.1_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Nervous System Malformations CTD Gene-Disease Associations 1.0 1.40316 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.831787 disability GeneRIF Biological Term Annotations 1.0 null GTEX-WWYW-0011-R10A-SM-3NB35 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835701 Specific granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.749 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.12963 GTEX-QCQG-0008-SM-48U2G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 microvessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.306444 GTEX-QV44-0008-SM-447AX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982968 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.723 UTP14C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49516 culture medium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.592444 GSE156115_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26889 thylakoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 3.21345 limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.087514 striatum_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11682 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85377 PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null GSE249714_0_v_1_anxa1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TERF2IP Pathway Commons Protein-Protein Interactions 1.0 null MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3904 GSE84678,GSE93902_1_v_2_bcl11b_human RummaGEO Gene Perturbation Signatures -1.0 null NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4166 Hepatomegaly CTD Gene-Disease Associations 1.0 1.68718 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7212 locus ceruleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25123 mecamylamine-hcl LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82808 CRCGN015_MCF10A.TP53.M_24H:E16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5825 prednisolone_homo sapiens_gpl570_gse32962 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null LN428 CCLE Cell Line Gene Expression Profiles -1.0 -3.49256 GSE120612_4_v_3_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null