association	dataset	threshold value	standardized value
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04999
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02379
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76628
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.13136
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.06489
Head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
Diabetic Neuropathy_Sciatic Nerve_GSE11343	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.69803
TCEAL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23092
Venous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.914
mantle zone of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33066
mantle zone of VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46067
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01492
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94274
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17929
SW1990	DepMap CRISPR Gene Dependency	1.0	3.96234
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824742
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.43987
presubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03443
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.89962
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.6339
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98238
RNF7	Pathway Commons Protein-Protein Interactions	1.0	null
CACNA1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17093
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33418
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1606
19658189-TableS5	GeneSigDB Published Gene Signatures	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03299
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
CENPVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73532
ZNF736	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60448
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.218544
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01814
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94234
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47163
Perturb_11979_KD_Etv5_SRP304972	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Keratoconus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06491
retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.808134
forms	GeneRIF Biological Term Annotations	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850141
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-1.078
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89637
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	1.67653
U2OS	CCLE Cell Line Gene CNV Profiles	-1.0	-3.12841
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041519
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45396
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70561
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86714
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110341_1_v_0_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43204
RPL38	Pathway Commons Protein-Protein Interactions	1.0	null
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11966
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33097
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054185
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	3.40163
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51468
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.73636
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39008
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5299
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30116
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33066
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66937
EZH2	ENCODE Transcription Factor Targets	1.0	null
blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.533475
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00497
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98056
MRPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39965
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060008
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96318
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965356
TMED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85557
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03492
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08035
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary angle-closure glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
KCTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69071
beta-N-acetylhexosaminidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.185
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043092
HOXC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38131
LRRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89738
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
VIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
Lysosomal lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73731
MTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81502
Perturb_9380_KO_lincRNAEPS_SRP354143	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
PANO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81654
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69147
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61574
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863421
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61758
protein ubiquitination	GO Biological Process Annotations 2015	1.0	null
COMMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52471
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.22789
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0719
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.1776
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31085
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1333
SW403	DepMap CRISPR Gene Dependency	1.0	2.60693
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91048
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35582
OLFML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4954
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0677
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846397
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54676
MTURN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40492
IRGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5634
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30116
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16625
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58993
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60864
CUX1-19635798-MULTIPLE-CANCER-TYPES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79341
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05635
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05322
GSE226114,GSE226116_2_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DUSP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79056
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.911854
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Optic atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.610697
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88482
SPI1	ENCODE Transcription Factor Targets	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8511326__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8505-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-syndromic X-linked intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8973
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57568
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16806
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
eye disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75976
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12984
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89984
Lung squamous cell carcinoma_LUSC_TCGA-70-6723-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.35805
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0056
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0904
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933955
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
Multiple myeloma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899868
SK-MEL-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891741
HOP92	CCLE Cell Line Gene CNV Profiles	1.0	1.95767
ROS-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lateral geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.096
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78441
short insular gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11362
eye and adnexa disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.03457
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0312
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11105
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847242
KE39	CCLE Cell Line Gene CNV Profiles	1.0	2.72234
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9472
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7775
CHAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84205
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34457
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.853247
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64328
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.03452
locus	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Low tension glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.512
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15713
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07627
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77244
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12143
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2977
ZNF804A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90888
KDM7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34307
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63467
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052401
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829155
ZSCAN29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55456
Perturb_3182_KO_Actn2_SRP218915	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.47456
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2481
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21148
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18008
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02553
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88482
SNAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20115
RBBP5	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869261
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0211
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
glaucoma	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938344
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMARCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29241
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23877
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0504
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084771
GSE153484_2_v_0_foxp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.541992
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60504
Lung squamous cell carcinoma_LUSC_TCGA-18-3419-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LTBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28221
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15502
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04713
TRIM28	ChEA Transcription Factor Targets	1.0	null
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68036
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.51842
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0689
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC5245798-pgen.1006538.s025.xlsx-Sheet1-GBX2_GBX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25517
Lung adenocarcinoma_LUAD_TCGA-49-6744-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10132
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.06489
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058133
f11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
r1 part of the 'mesencephalic' trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10829
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06188
skeletal muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14675
MINPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15663
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833082
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899868
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0383
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46067
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51342
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39549
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88808
PCI-15A	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.15179
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18349
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.980927
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62029
autophagic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.452825
DPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69331
GSE112860_5_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SQ-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGRMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44549
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73399
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62151
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.6127
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01578
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15463
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.24547
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.078
HEC151	CCLE Cell Line Gene Expression Profiles	1.0	1.40782
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34725
LARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24247
RH18	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35966
SLC25A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-370	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
intracellular part	GO Cellular Component Annotations 2015	1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860814
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968029
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.830414
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906257
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone marrow cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.237706
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14323
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30116
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83191
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28648
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25033
GSE254517_3_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
786O	DepMap CRISPR Gene Dependency	1.0	2.565
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM1A	Pathway Commons Protein-Protein Interactions	1.0	null
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
AGR3	Pathway Commons Protein-Protein Interactions	1.0	null
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90393
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.509
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73945
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19696
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53666
Giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.124
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01942
EW-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12087
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846397
162 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47246
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08855
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
meshwork	GeneRIF Biological Term Annotations	1.0	null
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86424
Autosomal recessive spinocerebellar ataxia 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.13844
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Juvenile glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
SCD_KO_GSE24243_46_mouse_Skin (8-9 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	0.899517
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76775
TRUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44171
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17929
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040967
Infantile hypophosphatasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
GSE213219_0_v_1_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14422
PMC5245798-pgen.1006538.s025.xlsx-Sheet1-ENSG00000168505_GBX2	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.742
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GALR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85553
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09296
NCIH1339	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46666
UMUC9	DepMap CRISPR Gene Dependency	1.0	3.36241
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10797
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56262
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23865
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885746
EBF1	ENCODE Transcription Factor Targets	1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-1.078
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01788
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04999
HOS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
K562	CCLE Cell Line Gene Expression Profiles	1.0	1.61314
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RGC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13927
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dinoflagellate hypocone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.412
ZRANB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54555
intermediate part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33066
intermediate isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03443
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16331
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09023
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19824
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38861
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
P3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45626
SLC25A5	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PHRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15135
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.936504
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953813
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879683
Glaucoma, Open-Angle	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-103a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-631	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63529
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963504
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.33791
Nemaline myopathy 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
Proteasome core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.238
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.48496
Perturb_8695_KO_Stat1_SRP364338	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MYOG	ENCODE Transcription Factor Targets	1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882822
DSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60181
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
Subiculum, dorsal part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1187
variants	GeneRIF Biological Term Annotations	1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHOX2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24729
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907796
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
inferior frontal gyrus, triangular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.884076
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57889
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.478
superficial stratum of PrS (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03443
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_ATF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82072
USP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92254
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19696
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31924
RUNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56995
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08327
heart	GTEx Tissue Gene Expression Profiles	1.0	1.31971
Lung adenocarcinoma_LUAD_TCGA-62-A470-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84002
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.356314
MYOG_myocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39366
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intergeniculate leaflet	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20121
Visual epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
intermediate stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53708
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34468
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04999
GSE88819_6_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHCHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20336
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67194
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54673
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88499
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16718
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TF1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04546
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4254	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55611
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093914
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00759
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cell wall-bounded periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
Hydrophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
molecular layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20121
Posterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56262
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.3185
cellular_component	GO Cellular Component Annotations 2015	1.0	null
TDRD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34738
POGLUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80027
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
r2 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46456
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11132
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911244
Anterior segment dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
EXOSC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90188
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1584
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-8200-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36643
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAVER1	DepMap CRISPR Gene Dependency	1.0	5.48118
Nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16331
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45464
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24702
Lung adenocarcinoma_LUAD_TCGA-78-7145-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10309_KO_Nos3_SRP286435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.10805
Autosomal dominant keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99333
TMED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55973
stomach	HPA Tissue Protein Expression Profiles	1.0	1.06489
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.78
HK2	CCLE Cell Line Gene Expression Profiles	1.0	1.76031
Midbrain reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00497
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57321
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879819
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
SERPINF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33778
ZNF143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53936
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMD	Pathway Commons Protein-Protein Interactions	1.0	null
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.73757
PTTG1IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.952
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00911
FTC133	CCLE Cell Line Gene CNV Profiles	1.0	1.36551
GRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58553
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02756
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
normal	GeneRIF Biological Term Annotations	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02553
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59858
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CROCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85634
anterior pretectal nucleus, dorsal core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53616
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946886
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.066
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00286
globe disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.4757
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59797
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37722
KMRC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03443
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05819
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61713
Eyebrow thickness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36154
retinal degeneration	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE241701_1_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_5_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92667
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69401
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
T47D	CCLE Cell Line Gene Expression Profiles	1.0	1.47103
cyclosporine_homo sapiens_gpl4133_gse25200	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931337
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44033
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44675
Scd1_DELETION_GDS4910_309_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
U-698-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal dominant distal hereditary motor neuronopathy 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12058
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1233
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08855
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.970025
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.902806
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052157
mantle zone of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45176
NB17	DepMap CRISPR Gene Dependency	1.0	5.29804
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07888
BCL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92327
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953813
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41956
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3948
hsa-miR-4768-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
DDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00068
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27203
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MHHES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54351
SNU626	CCLE Cell Line Gene CNV Profiles	1.0	1.51525
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4513
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15912
Intralaminar nuclei of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93324
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14932
KLF9_Deficiency_GDS2703_647_mouse_Jejuna - intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.36188
OCUM1	DepMap CRISPR Gene Dependency	1.0	3.36293
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8186
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.96702
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.28705
Buphthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04948
TIA1_KO_GSE54418_266_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
LAN2	DepMap CRISPR Gene Dependency	1.0	2.23827
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38019
GSE214514_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
CHKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67467
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51978
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41677
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10581
biological_process	GO Biological Process Annotations 2015	1.0	null
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18174
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30461
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-0.77671
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53777
salivary gland	HPA Tissue Protein Expression Profiles	1.0	1.06489
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05609
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9769
nucleus	GO Cellular Component Annotations 2015	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.1236
Charcot-Marie-Tooth disease axonal type 2P	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37269
Pigment dispersion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.781
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.3049
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14796
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELMOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50092
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61868
Retinal drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53673
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.52793
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846397
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7966
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11741
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70679
RAB33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11228
MYOD1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055979
VPS26B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88578
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56761
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16433
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FGFR3_knockdown_34_GDS4454	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.87125
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884431
increased hemoglobin content	IMPC Knockout Mouse Phenotypes	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.974745
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911303
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26004
GSE160077,GSE160084_3_v_0_bin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13356
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04164
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47187
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16973
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0892
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.3072
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9648
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARL1	Pathway Commons Protein-Protein Interactions	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69147
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8185
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11186
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3948
PIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52367
Perturb_4431_KO_Tnfrsf1b_SRP052924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.63601
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.575
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18039
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857664
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58792
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82669
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32268
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07999
Glaucoma	ClinVar Gene-Phenotype Associations 2025	1.0	null
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35435
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968879
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
GATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08335
NCIH1563	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47417
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.115
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37451
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71858
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46067
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.67608
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1738
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08855
Lung squamous cell carcinoma_LUSC_TCGA-34-5236-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.0345
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76513
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.22513
ZNF624	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76894
Metabolism of proteins	Reactome Pathways 2024	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49502
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32431
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.93233
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66673
Exfoliation syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
COLO684	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19605
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.966324
intermediate stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02623
Myeloid neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29486
nucleus	GO Cellular Component Annotations 2023	1.0	null
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03327
HS695T	CCLE Cell Line Gene CNV Profiles	1.0	1.42618
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9577
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.775
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85796
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13927
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Glaucoma 1, open angle, F	ClinVar Gene-Phenotype Associations	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
X-linked cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855219
middle frontal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94379
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02756
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17929
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nrf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BATF	ENCODE Transcription Factor Targets	1.0	null
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.62954
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56982
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.999158
Aniridia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
VTI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94082
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71588
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26895
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased heart weight	IMPC Knockout Mouse Phenotypes	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980325
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.0345
f1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
LCLC97TM1	DepMap CRISPR Gene Dependency	1.0	3.80202
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2097
PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.39772
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2934-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-2.09207
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26536
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	3.40544
PIGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81825
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04428
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QTRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59371
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12086
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16331
496100635_HIP_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09816
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00997
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5868
TCF3	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prosomere 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33066
mRNA_RHOX6_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.328
Primary somatosensory area, barrel field, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27057
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21504
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044157
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PRDM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38787
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8085
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15912
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50192
PAX5	ENCODE Transcription Factor Targets	1.0	null
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20759
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39724
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17928
PMC7846764-41598_2021_81773_MOESM2_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01378
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0951
HUNS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68828
VPS26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44943
SKRC20	DepMap CRISPR Gene Dependency	1.0	7.23624
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.77494
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lens cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
RBMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10183
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29226
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65376
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Ankyrin repeat-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
f2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
GATA1	ENCODE Transcription Factor Targets	1.0	null
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14497
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0768
Gordon Holmes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
NCIH1693	CCLE Cell Line Gene CNV Profiles	-1.0	-2.32239
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A101D	COSMIC Cell Line Gene CNV Profiles	1.0	2.12439
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33791
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	2.60991
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97827
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HIPK2_overexpression_28_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.49206
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67497
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10059
ZNF689	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1316
21152935-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22227
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36154
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63757
ZNF595	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98876
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35338
Peroxisomal biogenesis disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09511
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25954
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	1.55009
HNRNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12489
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2259
Lafora disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40337
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85243
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.058598
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.76667
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09793
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052704
CNNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19852
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61347
TAF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
YTHDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65009
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.943
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.5596
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7775
Immune System	Reactome Pathways 2014	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.214
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4924
mantle zone of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47274
Lung adenocarcinoma_LUAD_TCGA-MP-A4T9-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
proteasome core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.710136
FIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22744
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
Human - Tonsil - L2 - GC LZ Noproli	HuBMAP Azimuth Cell Type Annotations	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.078
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1432
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gyrus rectus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.963334
HIPK1_knockout_170_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.722138
NCIH446	DepMap CRISPR Gene Dependency	1.0	5.5096
RAD21	ChEA Transcription Factor Targets	1.0	null
SAOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skeletal muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.885915
HNF4A	ENCODE Transcription Factor Targets	1.0	null
skin	HPA Tissue Protein Expression Profiles	-1.0	-1.078
SCS214	DepMap CRISPR Gene Dependency	1.0	2.21004
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.53798
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45347
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1404
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.3643
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873179
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18343
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Channelopathies	DisGeNET Gene-Disease Associations	1.0	null
A3-KAW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37156
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
ID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40117
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68976
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29043
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
RCHACV	CCLE Cell Line Gene Expression Profiles	-1.0	-2.17737
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.5816
SK-MM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36154
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.91774
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925208
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Hoof	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
MOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66678
Retinal ganglion cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
Enterovirus 71_4Hour_None_GSE15323	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.01842
PSMA4	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826851
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.0566
TGFBR2_knockout_295_GSE45968	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.37143
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59635
Ocular hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.917
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55124
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25378
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC7642974__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44163
SMAD2	ChEA Transcription Factor Targets	1.0	null
Ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.952
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27438
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47138
pretectal nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890061
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
3MC syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
Perturb_17753_KO_Nae1_SRP407900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Neddylation	Reactome Pathways 2024	1.0	null
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PHOSPHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9306
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07339
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42528
ZBTB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2294
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.84039
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39313
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36154
Nonpigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.607
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	1.0	6.12127
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.751
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.08305
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5011
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
increased hematocrit	IMPC Knockout Mouse Phenotypes	1.0	null
A101D	CCLE Cell Line Gene CNV Profiles	1.0	2.11983
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
openangle	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-syndromic intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Perturb_6975_OE_Alox12_SRP320989	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.05736
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25783
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74698
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68817
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45153
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16331
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01652
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80549
Zellweger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1215
CLDN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93902
LAMTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82828
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74235
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05816
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09933
Hennekam syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30761
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07834
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22424
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16832
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10338_KO_Nos3_SRP286435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.37158
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27267
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32535
hsa-miR-619	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2261
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Immune System	Reactome Pathways 2024	1.0	null
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
SETDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06791
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042546
DLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.3032
CSDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57874
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13901
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
mRNA_ZFAND3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66833
Eye disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Primary congenital glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.426
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
CUL5	Pathway Commons Protein-Protein Interactions	1.0	null
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.901721
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.078
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29269
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.851589
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35659
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57375
SOCS protein, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41613
KYM1	DepMap CRISPR Gene Dependency	1.0	3.16033
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.736
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.924546
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-2467-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.06489
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.433
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-2.50275
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
LDLRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54042
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Class I MHC mediated antigen processing & presentation	Reactome Pathways 2014	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85068
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07299
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8766
cause	GeneRIF Biological Term Annotations	1.0	null
planum polare, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846644
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43204
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83614
CPEB1_01_20	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.17726
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04614
MCCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
CL11	CCLE Cell Line Gene CNV Profiles	1.0	1.54452
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.940992
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.26711
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Excessive tearing	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976807
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36155
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08217
HOS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62252
open-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.3193
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06349
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60691_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64463
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	1.98051
KO52	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00414
RPS10	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02041
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052142
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61905
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56772
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08383
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37678
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29572
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41684
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
C19orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3997
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4566
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9845
JHH-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8797
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05839
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073665
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09137
SET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8673
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40921
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	2.19484
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57787
GIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33838
Inflammation	CTD Gene-Disease Associations	1.0	1.28889
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
SLC45A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20552
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26322
Superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44538
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847242
intermediate stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46364
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.24114
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966773
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3795
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1985
Post-translational protein modification	Reactome Pathways 2024	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52091
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49783
EWSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77336
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05401
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50984
Perturb_9304_KO_Gsk3b_SRP295417	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13743
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49124
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09584
Endometriosis_Endometrium_GSE7305	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52763
ZFAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37382
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM216A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95011
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245491
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.747927
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49518
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GD-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70904
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40929
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4862
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24709
Opitz GBBB syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86476
HGH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.48682
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45464
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835293
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Increased Cup-To-Disc Ratio	DisGeNET Gene-Phenotype Associations	1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62151
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5077
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB453	DepMap CRISPR Gene Dependency	1.0	2.54364
CPVL	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18246
M band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08855
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45583
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69133
r2 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45176
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1926
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C14orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60747
GSE148066,GSE157787_2_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Adaptive Immune System	Reactome Pathways 2014	1.0	null
SATB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18576
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41423
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
Loin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
ADAM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1056
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31924
F5 meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5493
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06019
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.564
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32755
NCIH841	DepMap CRISPR Gene Dependency	1.0	4.47702
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04283
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE124410_6_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.71843
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55135
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67902
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUX1	ChEA Transcription Factor Targets	1.0	null
KLF7_KO_GDS2069_68_mouse_olfactory epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.55978
Autosomal dominant distal hereditary motor neuronopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
GSE210580_3_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.836017
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64871
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14554
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29486
Hypophosphatasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
HCC364	CCLE Cell Line Gene Expression Profiles	1.0	1.82226
GSE224970,GSE224971_1_v_0_sap30_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95954
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.989837
XRCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31217
posterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.946232
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Reticulum trabeculare	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.548
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41309
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584022
HCC2814	CCLE Cell Line Gene Expression Profiles	1.0	1.37681
HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TNS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74201
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6829
GSE230263,GSE230265_6_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
hsa-miR-3661	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Interval angle-closure glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847242
non-syndromic X-linked intellectual disability 103	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.042
C16orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00585
SLC7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30346
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969955
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43204
BCL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15988
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0942
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.87063
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
pathways	GeneRIF Biological Term Annotations	1.0	null
Retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.089
Perturb_13468_Mut_Ar_SRP045727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.3159
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.31794
RIDDLE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7799
Peters anomaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5368
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21214
PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.786514
medial orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894786
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.15179
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
Anterior chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
Kleefstra syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.869
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NT5C3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95497
NB14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67799
Perturb_9306_KO_Gsk3b_SRP295417	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157904_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
MTRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6867
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05872
C10	DepMap CRISPR Gene Dependency	1.0	2.52768
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1926
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95759
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44487
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02504
muscle	GTEx Tissue Gene Expression Profiles	1.0	1.54187
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25882
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GABARAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61522
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29017
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95729
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02553
Charcot-Marie-Tooth disease type 2R	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.842
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43499
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.829117
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.541605
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50984
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12997
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Axenfeld-Rieger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13944
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40473
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99333
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6412
Perturb_572_KO_Plod1_SRP321648	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.6907
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.928325
skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75597
ABCB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90157
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09086
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48595
increased heart weight	MGI Mouse Phenotype Associations 2023	1.0	null
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29661
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.018
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.07342
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82431
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amphisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.53726
Ocular Hypertension	DisGeNET Gene-Disease Associations	1.0	null
SPATA33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65692
WTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.51871
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0773
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44581
Perturb_13467_Mut_Ar_SRP045727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97098
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.286
FOXP1	ChEA Transcription Factor Targets	1.0	null
MDST8	DepMap CRISPR Gene Dependency	1.0	2.51826
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SJ-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
KYO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4398
low tension glaucoma	GAD Gene-Disease Associations	1.0	null
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retinal macular dystrophy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
HDAC2	ENCODE Transcription Factor Targets	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4711-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72352
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6776
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.0595
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052401
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88505
Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114992,GSE114993_0_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.06489
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NS-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMRC20	CCLE Cell Line Gene CNV Profiles	1.0	1.54564
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16951
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.32392
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.47211
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Glaucoma	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42602
increased hemoglobin content	MGI Mouse Phenotype Associations 2023	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65091
F-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.01417
Antigen processing: Ubiquitination & Proteasome degradation	Reactome Pathways 2024	1.0	null
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
MRPL23	Pathway Commons Protein-Protein Interactions	1.0	null
nobox_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.039457
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907796
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JC-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12038_KO_Trps1_SRP201986	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.61764
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57325
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954033
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08581
posteroventral part of alar p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27498
SLR23	CCLE Cell Line Gene Expression Profiles	1.0	2.26223
RDES	DepMap CRISPR Gene Dependency	1.0	3.219
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57458
frontal operculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923493
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79368
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44483
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_768_mouse_Skin - 7 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
GSE185944_2_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Iridogoniodysgenesis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.918
SETDB1	ChEA Transcription Factor Targets	1.0	null
MAPKAPK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6722
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08955
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91679
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953813
PMC3470785-NIHMS377161-supplement-14.pdf-526-ZNF114_ZNF114	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.4907
TCF3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43109
Leukocyte disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
Retinal macular dystrophy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.899
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14757
FXYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68972
Subiculum, dorsal part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30116
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45346
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20121
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859917
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2514
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7775
Acute closed-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
MAX	ENCODE Transcription Factor Targets	1.0	null
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58068
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5489
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
MAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05567
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.078
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30116
STOML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67499
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0504
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2436
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50917
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1569
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3948
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3558
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0504
NB1643	DepMap CRISPR Gene Dependency	1.0	3.51208
Phacogenic glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.862
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0397
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6864
MTARC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92453
Perturb_2195_KO_Tnfaip3_SRP103751	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.27747
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.6381
DTX3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84199
SNU245	CCLE Cell Line Gene Expression Profiles	1.0	1.49412
protein modification by small protein conjugation or removal	GO Biological Process Annotations 2015	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57536
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_16573_KO_Grn_SRP070944	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.97959
OCIM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94355
HCC1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.12439
PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.576
OE19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00497
SUDHL8	DepMap CRISPR Gene Dependency	1.0	7.60144
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2884
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35754
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55591
metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEMA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50898
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18206
ubiquitinmediated	GeneRIF Biological Term Annotations	1.0	null
LHX1_NULL MUTATION - Ablation_GDS1748_749_mouse_Embryonic kidneys (from day E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2085	CCLE Cell Line Gene Expression Profiles	1.0	1.66951
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4178
TCEB2	Pathway Commons Protein-Protein Interactions	1.0	null
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7496
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.01079
JMJD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20828
UMUC7	DepMap CRISPR Gene Dependency	1.0	2.52263
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991187
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.17984
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89282
MCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73707
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969056
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907796
furan	CTD Gene-Chemical Interactions	1.0	null
NNAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82962
Glaucomatous Visual Field Defect	DisGeNET Gene-Phenotype Associations	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59519
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLHL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57104
tension	GeneRIF Biological Term Annotations	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21859
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885501
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1675
WSU-DLCL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary open angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.38166
NLRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41186
Doyne honeycomb retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1187
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22796
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30143
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04578
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.866855
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23877
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-11A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44812
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64522
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
ATP5F1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88918
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56582
Perturb_16478_OE_Klk6_SRP245408	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Muscle-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.250433
Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95527
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41571
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.997802
C1QL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21239
SOD2_KO_GDS1080_128_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OVCAR5	CCLE Cell Line Gene CNV Profiles	1.0	2.16212
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11322
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	1.68598
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5277
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32294
Sclerotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.124
RNASEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95822
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50603
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13714
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.0563
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03705
skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.594853
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847242
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	1.40593
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842673
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02875
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.956971
Syndromic X-linked intellectual disability Turner type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.918
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909502
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.52884
ASPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53386
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73076
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25034
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01841
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043911
IFI6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23465
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0594
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary	GeneRIF Biological Term Annotations	1.0	null
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1-19884255-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08855
Cellulose microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75942
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41309
FOXL2NB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52779
TIA1_KO_GSE54418_265_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928455
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.60225
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35435
KNS81	DepMap CRISPR Gene Dependency	1.0	2.53288
caudal group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21421
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24833
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRRC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60985
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36499
outer CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851377
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83821
MM253	DepMap CRISPR Gene Dependency	1.0	2.59466
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16718
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A3	Pathway Commons Protein-Protein Interactions	1.0	null
Chromosome 22q11.2 microduplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
TMEM30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57858
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12405
CFAP126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90657
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80552
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962769
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39323
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836231
PMC7642974__F1	PFOCR Pathway Figure Associations 2024	1.0	null
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1395	COSMIC Cell Line Gene Mutation Profiles	1.0	null
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.869059
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55447
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-2.24385
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mendelian	GeneRIF Biological Term Annotations	1.0	null
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4549
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41424
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14456
ZNF837	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3207
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0894
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137914_4_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27478
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8669
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68143
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8546
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.52884
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
occipito-temporal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857119
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73732
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.878512
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5001
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38179
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99923
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01942
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
JHUEM1	DepMap CRISPR Gene Dependency	1.0	5.03027
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C10orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82599
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
496100660_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.71837
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACYP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09156
Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1418
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31924
angle-closure glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850566
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65726
NCIH28	DepMap CRISPR Gene Dependency	1.0	5.66517
Kaufman oculocerebrofacial syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
TBC1D17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44925
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82433
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE230263,GSE230265_3_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.07526
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99333
Perturb_15698_KO_Parva_SRP331642	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.40964
Kleefstra syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_4141_KO_Apoe_SRP131850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.316
mantle zone of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03443
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37898
Perturb_17721_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.0982
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20576
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09078
suggested	GeneRIF Biological Term Annotations	1.0	null
glaucoma 1, open angle, f	OMIM Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5165-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37833
FGFR3_knockdown_173_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.8712
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
Ankyrin repeat	InterPro Predicted Protein Domain Annotations	1.0	null
C32	CCLE Cell Line Gene CNV Profiles	1.0	2.73745
SK-PN-DW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882822
PGM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84771
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-3154	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22397
Amphisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10108
hsa-miR-107	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Tek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.167
H2BW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51563
KMH2	CCLE Cell Line Gene CNV Profiles	1.0	2.05443
open-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.956
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3936
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.92173
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99333
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02255
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YAPC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60055
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59693
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17929
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5495
Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06074
HNF4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43707
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66288
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.557
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93944
SOX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72425
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16331
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03443
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90652
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33738
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13789
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OACP4C	COSMIC Cell Line Gene CNV Profiles	1.0	2.12439
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.048
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27969
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160373_8_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37764
AP1G1	Pathway Commons Protein-Protein Interactions	1.0	null
ZFP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90916
WM983B	DepMap CRISPR Gene Dependency	1.0	2.46731
biological regulation	GO Biological Process Annotations 2015	1.0	null
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64174
Primary somatosensory area, mouth, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0672
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857664
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30027
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TG-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85513
EPLC272H	CCLE Cell Line Gene Expression Profiles	1.0	1.76016
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4IJ-01A-31R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040815
DIS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50492
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.66693
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24344
SAP30	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.6354
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899868
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
SNX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38994
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-1.078
Adaptive Immune System	Reactome Pathways 2024	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7775
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	3.60566
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.79254
ARFGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.27771
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76846
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52266
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.615124
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
WWC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24497
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849722
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.62932
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907796
GMEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49397
GSE108614,GSE108615_0_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1926
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12658
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.957169
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53207
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Striatum-like amygdalar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24833
Perturb_6332_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.2519
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4655
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRG_RXRG	Rummagene Transcription Factor Associations 2026	1.0	null
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5562
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14311
Antigen processing: Ubiquitination & Proteasome degradation	Reactome Pathways 2014	1.0	null
CAS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19908
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0768
Aggresome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.063
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842295
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Supratrigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01841
Renal underexcretion gout	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.609691
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44477
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03443
nucleus	GO Cellular Component Annotations 2025	1.0	null
Iris disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.839
REST	ChEA Transcription Factor Targets	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.06489
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22318
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22773
AFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80874
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987025
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.929812
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468436
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51468
MRPL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83589
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3160_Mut_Bag3_SRP151238	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31215
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837303
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.538118
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69147
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.79268
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9050671-41598_2022_10725_MOESM1_ESM.docx-4-ZNF655_ZNF655	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EIF4EBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84473
PXDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25653
hsa-miR-620	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.9247
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	3.15545
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95364
granule cell layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15912
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65105
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.28183
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71539
periventricular stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1187
C19orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05957
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16478
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52879
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40453
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12405
Cerebellar ataxia type 48	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
glaucoma	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38436
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6075
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05271
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
layer 4 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00497
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39625
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051403
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.781
RI1	DepMap CRISPR Gene Dependency	1.0	3.38715
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00588
USF2	ENCODE Transcription Factor Targets	1.0	null
PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88482
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24679
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7775
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GLOD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03445
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11862
GSE198036,GSE198041_4_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.783084
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.842
SKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44428
dermal fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.755777
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8424
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952954
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04603
MIEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40394
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.90572
Perturb_7083_KO_Jmjd4_SRP393926	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.74291
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20121
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95716
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5712
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16832
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30419
RAB3A_KO_GDS2482_705_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.90572
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9684
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847242
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8302
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53303
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.94503
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
STUB1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1937
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62965
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69155
open	GeneRIF Biological Term Annotations	1.0	null
NKAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47414
cd92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74984
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05625
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NOL4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6795
superficial stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7775
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20938
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.907887
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053433
Dentate gyrus, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15912
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78309
degradation	GeneRIF Biological Term Annotations	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.998259
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16858
ACTMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15255
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.98231
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853201
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30426
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4073
GSE210580_3_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.06489
Primary open angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.979
protein modification by small protein conjugation	GO Biological Process Annotations 2015	1.0	null
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49378
RTL8C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83512
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.2
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
dexamethasone_mus musculus_gpl6105_gse44208	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05723
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OCUG1	DepMap CRISPR Gene Dependency	1.0	18.6207
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17929
Subiculum, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51468
HTR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57928
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00497
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q1-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.85947
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-7q36_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954725
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.72218
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825622
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	1.62025
hsa-miR-4438	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64625
Low Tension Glaucoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16692
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.23725
non-syndromic X-linked intellectual disability 101	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.075
NOMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87942
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993437
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7775
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95286
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050372
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.644586
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054261
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41682
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36154
Perturb_6341_KO_LONP1_SRP353442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHTOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24802
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
ZNF879	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26692
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31411
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913579
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857024
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16832
GCLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54541
TCEB1	Pathway Commons Protein-Protein Interactions	1.0	null
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49168
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Axenfeld-Rieger syndrome type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78984
CIDEC_KO_GDS3776_552_mouse_Brown and white adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DMRT1	ChEA Transcription Factor Targets	1.0	null
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
NRBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36633
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7775
SMAD3	ChEA Transcription Factor Targets	1.0	null
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948223
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37242
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AG-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3541
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3894
GSDMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17401
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.068
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Perturb_15364_KO_Mef2c/Mef2d_SRP064307	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Bone marrow disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01352
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32889
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	152.804
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3517
periventricular stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03443
HSPB1	Pathway Commons Protein-Protein Interactions	1.0	null
KDM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48368
angle	GeneRIF Biological Term Annotations	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Corneal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Syndromic X-linked intellectual disability Cabezas type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14123
inclusion body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.445275
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05468
FSP27_KO_GDS3768_514_mouse_White adipose tissue  (WAT)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052483
Scotoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.091
ALX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43293
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94894
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51507
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.7773
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0504
HTR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52638
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.10737
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69147
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
steroid-induced glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
nonsynonymous	GeneRIF Biological Term Annotations	1.0	null
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49873
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867721
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12272
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.9915
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65937
Limited scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
CERS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57571
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
KDM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67365
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.781144
Autosomal dominant sensory ataxia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.024
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7237
ZNF827	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75965
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130217_0_v_2_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B4GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67524
VRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68677
subpallial amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3948
r1 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02623
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98568
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
NETO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82402
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Low Tension Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55568
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47607
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36154
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45464
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882614
RUNX1	ChEA Transcription Factor Targets	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22424
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30116
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34945
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864788
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11905
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39567
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45171
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.264
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87378
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27882
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
aggresome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.904138
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152432_9_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nail-patella syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69147
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6841
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.08055
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS294T	DepMap CRISPR Gene Dependency	1.0	2.72925
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59319
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34646
Class I MHC mediated antigen processing & presentation	Reactome Pathways 2024	1.0	null
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58171
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87308
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	2.2233
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27498
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16625
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
increased hematocrit	MGI Mouse Phenotype Associations 2023	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11144
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.93299
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10108
Nanophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FXYD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98208
GSE207433_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30355
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83176
LRRC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09783
PL18	COSMIC Cell Line Gene CNV Profiles	1.0	2.12439
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBB6	Pathway Commons Protein-Protein Interactions	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.24654
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85923
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03138
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55032
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_6342_KO_LONP1/ATF4_SRP353442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03518
RCC-FG2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70216
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1926
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88482
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044637
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18906
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057824
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62708
CERT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69172
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1187
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1957
PI4KB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24686
U343	CCLE Cell Line Gene Expression Profiles	1.0	1.42276
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50111
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RB1_KD_GSE50532_627_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.42947
ZFYVE19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053