association	dataset	threshold value	standardized value
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
PMC7846764-41598_2021_81773_MOESM2_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0996
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5841
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91853
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4873-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46645
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953538
SHFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06454
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52414
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CXCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60527
ZNF552	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67797
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.993324
BICR31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60319
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950266
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.926399
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928292
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17873
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PH-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37207
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.832319
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
obesity	GWASdb SNP-Disease Associations	1.0	1.04266
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87085
PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	1.28906
CAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5071
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
D-245MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02101
FBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97218
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.08049
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3094
BT12	DepMap CRISPR Gene Dependency	1.0	2.05167
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5397-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72438
MHCC97-H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
SF539	CCLE Cell Line Gene CNV Profiles	1.0	1.63616
PHF8	ENCODE Transcription Factor Targets	1.0	null
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PCGF2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Educational attainment	GWAS Catalog SNP-Phenotype Associations	1.0	0.463473
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.93428
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PRDM16_DEPLETION_GDS4021_460_mouse_WAT - white adipose tissue (stromal-vascular cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05387
SRD5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04505
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32107
DIMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88683
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07831
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64485
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Scoliosis, Isolated, Susceptibility To, 3	DisGeNET Gene-Disease Associations	1.0	null
Perturb_14281_KD_XRN1_ERP131052	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.31049
Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Noma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
SG231	DepMap CRISPR Gene Dependency	1.0	2.32733
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87572
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11362
Actin body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.424
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11003700-pbio.3002240.s011.xlsx-MYCN-IMR32_RawData-Unnamed_2_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2767
RUNX2	ChEA Transcription Factor Targets	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913765
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6503
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04782
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03918
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5121
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36532
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3133
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38089
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-PRRX1-sequence_name_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42911
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.99185
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35265
Immune System	Reactome Pathways 2014	1.0	null
protein modification by small protein conjugation or removal	GO Biological Process Annotations 2015	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963342
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5114
COX6B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3341
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65987
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tongue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76832
POLR3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21838
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.824451
NCO2	DepMap CRISPR Gene Dependency	1.0	2.12015
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827147
Pseudohypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42269
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11997
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56519
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02664
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5152
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47493
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.91926
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42863
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31956
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.883532
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75499
CFAP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24186
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1916
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56088
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Methionine	CTD Gene-Chemical Interactions	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.34595
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42308
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37401
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855876
ANKRD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27075
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76124
GSE158834_1_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.852023
Perturb_6332_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.0372
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.37674
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11978
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.554
VAMP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45503
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.860468
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3673
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.35428
GSE182680,GSE182683_0_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hmgn1_KO_GDS5010_406_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94407
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24523
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11554
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IZ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31956
Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.36191
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5902-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22265
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01092
PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03307
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09064
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08329
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75863
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5686
GSE252857_1_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37386
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5139
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75133
SUZ12-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
APOD_KO_GDS3913_487_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57162
H1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34397
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4902-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF516	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30592
Preeclampsia_Placenta_GSE4707	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.74444
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841511
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIPK1_knockout_170_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.783284
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77294
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Dorsal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH650	DepMap CRISPR Gene Dependency	1.0	8.73404
HNRNPA2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47804
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RCC-JW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32726
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-8124-11A-01R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10381
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871592
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62026
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864066
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57487
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15661
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A5	Pathway Commons Protein-Protein Interactions	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.866898
PCDH12_Deficiency_GDS3415_577_mouse_Embryonic placentas (12.5 day)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXD4L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26055
RAB3A_Mutation - D77G point mutation_GDS2482_702_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE252857_1_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4999
SPARC_Deficiency_GDS3636_524_mouse_Lens epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_16479_OE_Klk6_SRP245408	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ERH	Pathway Commons Protein-Protein Interactions	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18928
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17284
Lung adenocarcinoma_LUAD_TCGA-05-4382-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9994
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5622
biological regulation	GO Biological Process Annotations 2015	1.0	null
Adolescent Idiopathic Scoliosis	DisGeNET Gene-Disease Associations	1.0	null
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67677
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10891
Rectum adenocarcinoma_READ_TCGA-G5-6235-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU201	DepMap CRISPR Gene Dependency	1.0	2.3807
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89022
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36079
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73787
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8063
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19233
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76537
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7760_KD_RRP6/DIS3_SRP337423	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.18926
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THRAP3	Pathway Commons Protein-Protein Interactions	1.0	null
heart	GTEx Tissue Gene Expression Profiles	1.0	1.75928
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890073
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RO-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased circulating bilirubin level	MGI Mouse Phenotype Associations 2023	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1758
TFG	Pathway Commons Protein-Protein Interactions	1.0	null
pontine reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.846502
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74166
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33114
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.04642
VPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04699
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55066
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.037
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913765
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835964
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77133
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4825
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87102
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5168
HS729	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35806
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52414
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.651059
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998199
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5098
GB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGFBR2_knockout_295_GSE45968	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	3.96293
PMC8511326__F4	PFOCR Pathway Figure Associations 2024	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8745
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66434
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22476
PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82786
muscular disease	GWASdb SNP-Disease Associations	1.0	0.287595
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.51253
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8687
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ulcerative stomatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.14473
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31729
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.356732
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05725
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	6.62305
PABPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21547
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36613
Perturb_7125_KO_Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.90699
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68513
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39287
ZBED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26123
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67023
TF1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.70264
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15758
Rectum adenocarcinoma_READ_TCGA-F5-6811-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916974
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WQ-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pluteus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996902
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13927
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981627
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35186
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11384
SOCS protein, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996244
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05044
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34952
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EK-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16403
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BL-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17035
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.938209
SERPINE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44955
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5698
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51768
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57919
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86196
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88175
Perturb_6341_KO_LONP1_SRP353442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.4393
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866425
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55429
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1284
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80865
DAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10039
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70216
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42488
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45293
MID1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09934
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21763
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31729
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.926399
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2857
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890073
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5DU-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53935
PPP1R15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39962
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.77866
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19434
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68596
MED19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40797
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4626
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996244
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52414
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54388
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40915
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998199
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24429
AHSA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51826
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01499
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5994
C32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57421
Blastopore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.106
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8457
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47822
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
Cholesterol, LDL	dbGAP Gene-Trait Associations	1.0	0.609816
Brain Lower Grade Glioma_LGG_TCGA-DU-7302-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ERGIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77213
496100570_HIP_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.41554
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89471
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03047
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4803-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50842
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11509
EZH2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90701
Melanosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99729
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76531
SMARCA4_02_47	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.51096
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18627
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55043
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1888
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71043
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7939
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65923
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12222
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49957
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.984621
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF_02_85	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.43296
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Post-translational protein modification	Reactome Pathways 2024	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1054
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GADD45G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57051
TP53INP2_OE_GDS5054_545_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11268
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859563
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11384
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36547
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39771
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977007
Perturb_6837_KD_TGM2_SRP194250	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.89679
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05219
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EI-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.82416
DUX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24762
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1044
GPRASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78671
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71453
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.5676
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928292
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01480	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.55113
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74862
FASTKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64273
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OC-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44102
Body Mass Index	dbGAP Gene-Trait Associations	1.0	0.35211
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32327
NCIH1618	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95981
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	4.8677
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.587
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50493
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35128
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87419
Response to statin therapy	GWAS Catalog SNP-Phenotype Associations	1.0	0.314454
H3K9me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38077
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890073
MERO95	DepMap CRISPR Gene Dependency	1.0	3.92305
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.3595
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33325
Class I MHC mediated antigen processing & presentation	Reactome Pathways 2024	1.0	null
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83757
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996244
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77E-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100449_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18531
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	9.68336
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90931
GSE207914_5_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19975
Perturb_7708_KD_Spt6_SRP132004	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.33795
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	2.40879
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14733
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33626
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924069
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-0.867457
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859296
Lung adenocarcinoma_LUAD_TCGA-99-8032-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890073
Perturb_13780_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5211
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.482
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4211
FHIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54986
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.616
SFPQ	Pathway Commons Protein-Protein Interactions	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87919
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7401
ABCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88222
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36587
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.926399
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31564
SETD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57249
muscle tissue disease	GWASdb SNP-Disease Associations	1.0	0.312353
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.971003
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
body mass index	GAD Gene-Disease Associations	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35181
ABRAXAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27535
Perturb_14357_KD_SOX2_SRP341440	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.13733
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.27844
SIRT4_KO_GDS4823_505_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34441
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.22514
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16277
KRTAP13-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89615
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26172
GSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86176
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2748
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03314
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832594
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04256
PMC10994228-MOL2-18-939-s001.pdf-1-ARID5B_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH727	DepMap CRISPR Gene Dependency	1.0	2.74399
Perturb_6887_KO_PFDN5_SRP273783	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.36019
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.43406
SRSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
496100544_PCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38983
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832594
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6168
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JURKAT	DepMap CRISPR Gene Dependency	1.0	3.893
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81456
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22174
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43X-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0597
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63101
496100644_HIP_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02689
SOX2-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00925
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.51906
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42615
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.426872
Sarcoma_SARC_TCGA-DX-A48K-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49747
RAD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02079
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15546
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33727
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18432
KYSE410	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5276
PMC12789432-41467_2025_66251_MOESM4_ESM.csv--SOX2_tumorigenesis_signature_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18316
MCIDAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28201
IMR32	DepMap CRISPR Gene Dependency	1.0	3.69567
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89239
ARFGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74127
SNU423	DepMap CRISPR Gene Dependency	1.0	2.60251
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	3.95147
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A769-01A-32R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99729
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147240_3_v_4_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08865
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.3237
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63523
CAKI1	DepMap CRISPR Gene Dependency	1.0	2.84891
HSPBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23845
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21523
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5007-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Class I MHC mediated antigen processing & presentation	Reactome Pathways 2014	1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	3.20973
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.0003
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.52603
artery disease	GWASdb SNP-Disease Associations	1.0	0.314064
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81606
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996244
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875201
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.139988
CCDC87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68834
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07893
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	3.40026
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971727
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02029
PDGFRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81725
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NME1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF568	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46464
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869176
E2F3_KD_GDS4094_448_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
Perturb_2442_KD_DDX5/DDX17_SRP098687	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.03048
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892218
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38819
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21588
Brain Lower Grade Glioma_LGG_TCGA-RY-A847-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHCC97-L cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56855
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.901787
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13866
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.5656
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7721
SEC24D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05586
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2613
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60872
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.903001
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
THAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11634
Ankyrin repeat	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17873
PCSK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62105
muscle	GTEx Tissue Gene Expression Profiles	1.0	1.23083
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11664
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29891
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38293
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0347
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20175
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11899
PKP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23368
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54941
Perturb_11562_KD_BAX/BAK_SRP348085	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00902
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54325
EZH2	ENCODE Transcription Factor Targets	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.44902
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7643
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46746
G402	CCLE Cell Line Gene CNV Profiles	1.0	1.59391
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4276
MAVER1	DepMap CRISPR Gene Dependency	1.0	2.49049
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890073
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.842999
Lung squamous cell carcinoma_LUSC_TCGA-46-3769-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80511
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4861
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3268
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7521
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84822
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0787
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7435
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45213
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22994
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10559
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08508
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41934
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.082229
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.994373
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01109
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95001
FOXN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4589
RAD21	ENCODE Transcription Factor Targets	1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2011
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.0212
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36835
tongue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859126
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.178116
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03847
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBM6	Pathway Commons Protein-Protein Interactions	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57486
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.89266
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8198
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.0095
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860643
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947763
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2091
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10065
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920136
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95643
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.957479
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35922
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5995
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05286
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.17325
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7828
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02029
TCEB2	Pathway Commons Protein-Protein Interactions	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.7467
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902957
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86539
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12824
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13377
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PK-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12117
HASPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25589
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05387
Perturb_14982_KO_Setd1a_SRP330236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.9335
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31729
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09178
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03485
ZNF563	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56185
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06133
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977752
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A7I0-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859563
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	1.5461
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859563
TARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06046
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32211
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.841814
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80369
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25803
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21647
BL5433 (ERCC6)	NURSA Protein Complexes	1.0	null
Perturb_6342_KO_LONP1/ATF4_SRP353442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
HOS	CCLE Cell Line Gene CNV Profiles	1.0	1.53943
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	72.6196
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NINJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58636
EW22	DepMap CRISPR Gene Dependency	1.0	2.0188
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27972
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51208
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16363
Pigment granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47124
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6145
SW1116	DepMap CRISPR Gene Dependency	1.0	3.51836
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6861
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.891773
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948023
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41231
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
NFE2-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17363
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41264
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55566
BCLAF1	Pathway Commons Protein-Protein Interactions	1.0	null
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38287
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.69427
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7904
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09165
FABP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01692
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16424
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30019
CTNNB1_OE_GDS4449_352_mouse_Embryonic kidney from E12.5 embryos (-catGOF-UB mutant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5002
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01643
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC12498101-cd-24-1904_supplementary_tables_s1-s12_suppst1.xlsx-S7-Supplementary_Table_7_Human_tissue_RNA-seq_differential_analysis_for_SPOPmut_vs_SPOPwt_AA_vs_AG_and_AG_vs_GG_clone_data_DEG_set_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9417
disease	GWASdb SNP-Disease Associations	1.0	0.045411
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1548
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4685
NB13	DepMap CRISPR Gene Dependency	1.0	4.11854
SC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0346
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02852
metabolic process	GO Biological Process Annotations 2015	1.0	null
COL1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81139
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10237
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3179
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6422
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03847
FNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30353
Chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.916
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859563
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.93248
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.91506
TLDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03795
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85874
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64317
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08402
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
atherosclerosis	GWASdb SNP-Disease Associations	1.0	1.28906
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22876
chr2_236236838_C_T_b38	GTEx eQTL 2025	1.0	1.3862
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.671307
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834383
GSE158834_1_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70854
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J5-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7614
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.89191
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05348
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3635
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37401
Brain Lower Grade Glioma_LGG_TCGA-HT-7880-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21223
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09767
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3727
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2173
Rectum adenocarcinoma_READ_TCGA-AF-6655-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06286
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58186
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10079
Perturb_2386_Mut_ASXL2_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.80852
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4886
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65967
SP in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23289
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LUC7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62677
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23161
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4342
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7796
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859563
SH3D21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00786
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5308
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.836051
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10108
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4769
bladder	GTEx Tissue Gene Expression Profiles	-1.0	-1.59159
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71823
Endopeduncular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.551
GLC82	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34984
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913765
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28298
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0741
PDZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76659
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10891
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29303
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9699
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3411
NFE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92601
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38712
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42491
GSE137144_2_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52414
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32768
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33076
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.795516
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67389
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	4.27518
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57781
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2385_KO_ASXL2_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.77245
U-138MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86489
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93155
H3K36me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24694
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45654
vascular disease	GWASdb SNP-Disease Associations	1.0	0.241293
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5106-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.652205
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66722
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
QGP1	CCLE Cell Line Gene CNV Profiles	1.0	2.04558
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.940661
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17448
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02029
ZC3H12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26965
OVMIU	DepMap CRISPR Gene Dependency	1.0	3.59434
SW872	COSMIC Cell Line Gene Mutation Profiles	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.476145
Arsenic	CTD Gene-Chemical Interactions	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37401
TAX1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90643
Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40022
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.832319
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.833841
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39582
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30083
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06107
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41686
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53743
ETF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68219
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11348
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933865
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00891
TP63	ChEA Transcription Factor Targets	1.0	null
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.37227
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902957
Antigen processing: Ubiquitination & Proteasome degradation	Reactome Pathways 2014	1.0	null
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929552
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0309
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16478
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.753763
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Foot sole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
SP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78782
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Elongin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.723
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80389
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8609
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834085
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834085
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99729
HCC1359	CCLE Cell Line Gene CNV Profiles	1.0	2.36547
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928292
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853937
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36835
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831474
Rectum adenocarcinoma_READ_TCGA-AF-3911-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17159
MED29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22429
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09064
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0346
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927553
SF3B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64251
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137653_2_v_3_siglecf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87071
SP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16529
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824464
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937677
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VK-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.846059
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1699
TP53INP2_OE_GDS5053_312_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12738
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15539
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8971
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72438
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73116
JL1	CCLE Cell Line Gene CNV Profiles	1.0	1.47586
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.356732
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9139
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92159
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.7998
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8697
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01904
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31729
Immune System	Reactome Pathways 2024	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7786
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21395
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.3147
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.885298
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1811
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.4725
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92201
DACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11541
Adaptive Immune System	Reactome Pathways 2014	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26013
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.3347
arteriosclerosis	GWASdb SNP-Disease Associations	1.0	0.456271
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCC5	DepMap CRISPR Gene Dependency	1.0	2.73493
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
t70-white-adipose_male_2w	MoTrPAC Rat Endurance Exercise Training	-1.0	-12.2727
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13034
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4499
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996244
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15008
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902957
ABLIM1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31729
WSUNHL	DepMap CRISPR Gene Dependency	1.0	2.08268
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968119
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.238
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932002
FKBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67159
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.56206
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.308216
HCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0668
FAM98A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15306
STAT3	ChEA Transcription Factor Targets	1.0	null
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05637
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21206
ASS1	Pathway Commons Protein-Protein Interactions	1.0	null
H290	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
DBH_KO_GDS4324_362_mouse_Embryonic heart  E10.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SKMEL30	DepMap CRISPR Gene Dependency	1.0	4.89726
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911503
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824963
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6089
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927123
NCIH2882	DepMap CRISPR Gene Dependency	1.0	3.2933
RBPJ	ChEA Transcription Factor Targets	1.0	null
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79158
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35502
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.185
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WT-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.51438
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86967
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31699
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
SETD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66834
protein ubiquitination	GO Biological Process Annotations 2015	1.0	null
WM3211	DepMap CRISPR Gene Dependency	1.0	2.97674
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60153
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07307
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832594
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20356
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.7604
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.418789
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941621
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5935
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32177
AKR1B1	Pathway Commons Protein-Protein Interactions	1.0	null
OCIMY5	DepMap CRISPR Gene Dependency	1.0	2.1149
Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.854468
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33727
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930963
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03642
SKNSH	DepMap CRISPR Gene Dependency	1.0	3.28652
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92929
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3179
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913765
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8333
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04476
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31729
ZC3HAV1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04344
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39497
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIRT4_KO_GSE56321_391_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE137144_2_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52414
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36119
PRPS1	Pathway Commons Protein-Protein Interactions	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7301
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.17076
signal transduction	GO Biological Process Annotations 2015	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5413
Mouth	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39387
Perturb_6829_KD_CDK11_SRP156201	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.392
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18174
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05387
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90767
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859126
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13533
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66361
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857741
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913765
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UF-01A-23R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831802
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7105
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86028
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51533
H3K9me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19031
SW982	DepMap CRISPR Gene Dependency	1.0	4.86024
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60689
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.998373
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.03
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28705
GSE88819_6_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.832319
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4885-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBH_KO_GSE33906_53_mouse_heart (E10.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE202359_1_v_0_rbpms_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.984
RPL10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11018
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33727
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13778
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26919
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8225
cellular process	GO Biological Process Annotations 2015	1.0	null
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21182
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.25261
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.958
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61236
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.025
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53811
NAMALWA	DepMap CRISPR Gene Dependency	1.0	2.58022
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993599
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.187895
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.97268
WSB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28745
Perturb_7701_KD_Spt6_SRP132004	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.47432
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93076
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05258
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61289
ZNF556	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08784
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15452
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62903
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93168
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31944
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03051
SPATA5L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.569
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
JHU-022	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18174
SW948	CCLE Cell Line Gene CNV Profiles	1.0	1.37349
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39696
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43872
NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHLA10	DepMap CRISPR Gene Dependency	1.0	2.55381
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44402
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45501
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0239
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0654
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.56008
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10521
CES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.462
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RD	CCLE Cell Line Gene CNV Profiles	1.0	1.95059
Albright's hereditary osteodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
EAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14007
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34134
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27282
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.367761
arteriosclerotic cardiovascular disease	GWASdb SNP-Disease Associations	1.0	0.555938
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09064
HTK	CCLE Cell Line Gene CNV Profiles	1.0	1.65741
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00136
KE39	CCLE Cell Line Gene CNV Profiles	1.0	2.58509
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
myopathy	GWASdb SNP-Disease Associations	1.0	1.28906
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11608
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76925
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	4.3273
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834085
protein modification by small protein conjugation	GO Biological Process Annotations 2015	1.0	null
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25222
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38133
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN340	CCLE Cell Line Gene CNV Profiles	1.0	1.58398
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRSF6	Pathway Commons Protein-Protein Interactions	1.0	null
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72573
MON	DepMap CRISPR Gene Dependency	1.0	2.87724
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10447
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01015
TCEB1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
ChIP_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4844
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.711064
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02753
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.05682
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49512
KPNYS	DepMap CRISPR Gene Dependency	1.0	2.40505
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76875
POR_KO_GDS1678_762_mouse_Jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CDH4-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31118
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
DUXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.191752
Metabolism of proteins	Reactome Pathways 2024	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.8749
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69933
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.8897
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3468
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.926399
hypertension	GWASdb SNP-Disease Associations	1.0	0.500225
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42841
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68381
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TP53INP2_OE_GDS5054_387_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49473
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47658
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	1.12851
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22821
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GK_KO_GDS2610_162_mouse_Brown adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Midgut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38258
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95434
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31393
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.97268
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37026
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8315-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES5	DepMap CRISPR Gene Dependency	1.0	3.50007
Response to statin therapy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54676
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81812
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0419
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW1088	DepMap CRISPR Gene Dependency	1.0	3.14086
ZNF511	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66951
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41063
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59951
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_766_mouse_Skin - 0 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_3661_KO_EZH2_SRP211748	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.81641
cholesterol, ldl	GAD Gene-Disease Associations	1.0	null
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71175
colon	GTEx Tissue Gene Expression Profiles	-1.0	-1.04363
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.34276
PC14	CCLE Cell Line Gene CNV Profiles	1.0	2.20799
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61438
increased circulating bilirubin level	IMPC Knockout Mouse Phenotypes	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.977
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45617
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00357
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.757351
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rad51B-Rad51C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35777
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02029
Adrenocortical carcinoma_ACC_TCGA-OR-A5K2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37401
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17954
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.746
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2162
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2563
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.7565
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.876953
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4268
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2_Deficiency_GDS4853_322_human_AZ-521 gastric cancer (GC) cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE182680,GSE182683_0_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890073
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29371
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1005
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.455
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25678
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.120868
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05387
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23491
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997404
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_408_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52414
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834204
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.38492
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42023
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3537
H3K9me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48204
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
18794137-SuppTable1e	GeneSigDB Published Gene Signatures	1.0	null
DOTC2-4510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17487_KO_Elavl1_SRP153419	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.2499
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LXF289	CCLE Cell Line Gene CNV Profiles	1.0	1.36572
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922909
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884985
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80576
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Ankyrin repeat-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46768
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16691
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62194
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0999
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8081
2q37 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1554
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23308
CHP126	CCLE Cell Line Gene CNV Profiles	1.0	1.74754
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47989
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01083
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0883
Craniofacial microsomia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2301
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12196
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72032
CCDC103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5438
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60519
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941189
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4096
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.308216
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21501
all	GWASdb SNP-Phenotype Associations	1.0	0.039112
RPL15	Pathway Commons Protein-Protein Interactions	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03765
EXOC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68681
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
496100379_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92731
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kleefstra syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996244
Growth hormone receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48893
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31729
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2748
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1839
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37631
KLF15_Deficiency_GDS2687_649_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9114
PRPSAP1	Pathway Commons Protein-Protein Interactions	1.0	null
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29705
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95901
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13707
Adaptive Immune System	Reactome Pathways 2024	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7568
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19167
KINGS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75472
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09064
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.111102
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847309
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52414
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7191_KD_CNOT1_SRP335073	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.68659
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0781
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.331439
Plastron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29347
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.09016
Lung adenocarcinoma_LUAD_TCGA-91-6831-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29138
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62373
Chronic widespread musculoskeletal pain	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79695
KYSE450	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7374
SP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995431
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1018
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54876
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94082
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.990873
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.881225
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877595
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50971
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941621
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63556
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03258
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69119
CTCF	ENCODE Transcription Factor Targets	1.0	null
PCGF2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90334
MPP89	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20302
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59787
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EA-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-NSP_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837897
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10654
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35229
Perturb_18102_KO_Tbx20_SRP007579	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
POU5F1-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.901425
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31729
SLC25A6	Pathway Commons Protein-Protein Interactions	1.0	null
Archenteron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
TRMT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24779
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9593
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33284
Choline	CTD Gene-Chemical Interactions	1.0	null
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63687
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	1.49574
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46137
Antigen processing: Ubiquitination & Proteasome degradation	Reactome Pathways 2024	1.0	null
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55469
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859563
ARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60386
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SW626	DepMap CRISPR Gene Dependency	1.0	3.68878
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82205
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.914467
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2655
496100548_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60177
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.929729
AIFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03964
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15315
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38293
H3K9me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
TP53INP2_OE_GDS5054_385_mouse_Muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860288
TP53INP2_OE_GDS5054_276_mouse_SKM-Tg - Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.61317
MG63	DepMap CRISPR Gene Dependency	1.0	6.21518
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.946292
NZOV9	DepMap CRISPR Gene Dependency	1.0	3.61484
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.87
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9395
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35264
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13482
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.04163
MESP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49156
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5907-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57872
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89826
Perturb_14579_KO_LINC00901_SRP312185	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.89577
POLR3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29345
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09064
MERO82	DepMap CRISPR Gene Dependency	1.0	3.60796
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98237
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02525
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
KLF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26999
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894922
GSE77178_2_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6798
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49996
NCIH82	DepMap CRISPR Gene Dependency	1.0	5.08772
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
DHRS2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100377_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.76285
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96031
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66075
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	1.28282
SLAIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06473
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54175
CAOV4	DepMap CRISPR Gene Dependency	1.0	2.5594
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.21036
E2F6	ENCODE Transcription Factor Targets	1.0	null
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.24
Adrenocortical carcinoma_ACC_TCGA-OR-A5K9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941621
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.832319
NCIH2172	CCLE Cell Line Gene CNV Profiles	1.0	1.86391
SIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43226
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.97268
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09064
Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22128
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78688
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.950606
brain	GTEx Tissue Gene Expression Profiles	1.0	0.831526
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN319	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23327
HIPK2_overexpression_28_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.36841
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11915
METTL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3989
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.839921
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62059
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06536
CUL5	Pathway Commons Protein-Protein Interactions	1.0	null
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09773
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46482
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53353
RBM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02571
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.90774
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2694
Neddylation	Reactome Pathways 2024	1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11071
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.04831
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56751
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44642
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53493
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.942169
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13368
SH4	DepMap CRISPR Gene Dependency	1.0	2.06393
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.64312
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968094
A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79676
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52803
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61136
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0175
MYOC_OE_GDS1640_269_mouse_retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97599
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91757
SIRT4_KO_GDS4823_22_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
COLO-824	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
DDX56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22871
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10162
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.79213
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7891-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LSM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63862
SIRT4_KO_GDS4823_30_mouse_hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LIPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47235
HS695T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87892
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3372-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.838399
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7988
Catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51083
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8526
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42522
KNS60	DepMap CRISPR Gene Dependency	1.0	3.07866
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943878
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
icSARS CoV_48Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.98067
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4578
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7073
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36758