association	dataset	threshold value	standardized value
ATP4A	Pathway Commons Protein-Protein Interactions	1.0	null
ABCD1	Pathway Commons Protein-Protein Interactions	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.82994
adrenal gland	HPA Tissue Gene Expression Profiles	-1.0	-0.917388
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11261
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89926
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29105
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.83648
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03605
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53678
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0951
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60502
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48356
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MED30	Pathway Commons Protein-Protein Interactions	1.0	null
urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279724
ALDH2	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.085451
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.91173
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854965
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12683
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.828697
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988777
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.849285
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.66052
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.07295
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30012
PDCD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14861
anion binding	GO Molecular Function Annotations 2015	1.0	null
MARS	Pathway Commons Protein-Protein Interactions	1.0	null
UTP14A	Pathway Commons Protein-Protein Interactions	1.0	null
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15317
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6668
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.18844
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2966
SMG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19123
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
SEC63	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877445
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06643
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12472
CNOT11	Pathway Commons Protein-Protein Interactions	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
PRKACA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897681
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34153
Sengers syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF768	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74425
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10984
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.49749
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.863
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46945
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.825547
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.05362
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WM-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157397
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.949324
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18335
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80686
NCIH1385	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74255
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24528
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103619
SNU1196	CCLE Cell Line Gene CNV Profiles	1.0	1.95645
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42258
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11261
MUS81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14931
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.965196
TK-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.091
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.41772
GTEX-XBED-1626-SM-47JYN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851016
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CYFIP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64506
Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05948
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844208
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.96633
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
gas gangrene	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.613965
CAP1	Pathway Commons Protein-Protein Interactions	1.0	null
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67314
BJHTERT	CCLE Cell Line Gene Expression Profiles	1.0	1.96786
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09908
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05068
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11679
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98987
ESR1	Hub Proteins Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5645
GTEX-XGQ4-0826-SM-4AT4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0053
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916365
TRIP13	Pathway Commons Protein-Protein Interactions	1.0	null
EMTOKA	DepMap CRISPR Gene Dependency	1.0	3.77491
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907461
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.56889
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.903294
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47047
CORO7	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.52331
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887437
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
U118MG_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.33755
chr1_1497758_C_T_b38	GTEx eQTL 2025	1.0	1.1411
PMC11903305-41586_2024_8507_MOESM3_ESM.xlsx-Table_S1_MAF-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
IPC298	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38501
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42953
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85001
Perturb_8453_KD_ASGR1_SRP334678	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05241
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate	GTEx Tissue Gene Expression Profiles	1.0	0.989162
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.835239
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2692
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10998
Prostate adenocarcinoma_PRAD_TCGA-G9-6367-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03272
COLGALT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28884
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13454
NCIH292	DepMap CRISPR Gene Dependency	1.0	2.53217
GTEX-SE5C-2126-SM-4BRUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890746
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41518
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10946
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915883
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5692-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48436
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97759
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09377
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045464
XRCC4	Pathway Commons Protein-Protein Interactions	1.0	null
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13889
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57627
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99761
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17089
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.07089
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01126
GFPT2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1R3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84351
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63774
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0376
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047893
ZC3HAV1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843443
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oogenesis phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25737
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.22553
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13276
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1909	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
Mitochondrial alpha-ketoglutarate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37994
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911736
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37124
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09717
Cerebellar hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
CARD9	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-545	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
OACM5-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36871
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0727
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850277
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10415
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42654
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39558
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.50964
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849549
hsa-miR-527	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mitochondrion organization	GO Biological Process Annotations 2025	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A814-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18024
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11911
3-methylglutaconic aciduria type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3774
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857309
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90909
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04276
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.60797
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01415
MRPS22	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8448
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84204
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial prohibitin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.144
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2927
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
ERGIC3	Pathway Commons Protein-Protein Interactions	1.0	null
ATP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.50948
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83739
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.691094
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868625
SRP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41333
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
NR4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0849
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042833
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98068
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.952818
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4096
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931865
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88095
IL25	Pathway Commons Protein-Protein Interactions	1.0	null
essential	GeneRIF Biological Term Annotations	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.923726
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1089
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16252
ATPase family AAA domain-containing protein 3, domain of unknown function DUF3523	InterPro Predicted Protein Domain Annotations	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37454
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6181
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0907
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059778
BZW2	Pathway Commons Protein-Protein Interactions	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.257
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901002
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20229
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38513
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WASF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1737
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.82654
CSTF3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE218060_2_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1162
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45632
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.121
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.54851
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997911
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37238
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51E-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50551
thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100618
HARS	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01718
HLA-E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50257
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.920724
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943635
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06463
PDIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58852
hsa-miR-4483	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03616
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05131
SUDHL4	CCLE Cell Line Gene Expression Profiles	1.0	1.59916
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.68335
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
SLR21	CCLE Cell Line Gene Expression Profiles	1.0	1.54688
TARS	Pathway Commons Protein-Protein Interactions	1.0	null
decreased circulating cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38578
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09017
PMC12179083-Table_6.xlsx-VCF_Variants_Master_File-Gene_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976532
Lung adenocarcinoma_LUAD_TCGA-78-7153-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80869
PRMT5	Pathway Commons Protein-Protein Interactions	1.0	null
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
existing	GeneRIF Biological Term Annotations	1.0	null
HCC33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77813
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07083
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18205
ACTG1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16709
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0216
chr1_1482624_T_C_b38	GTEx eQTL 2025	1.0	1.10859
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27174
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856208
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057447
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893675
RNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11582
SUN2	Pathway Commons Protein-Protein Interactions	1.0	null
OVCA420	DepMap CRISPR Gene Dependency	1.0	4.62121
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43973
rectum_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.26733
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040506
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10246
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.977413
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992086
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
ALDH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00362
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967733
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923888
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40733
protoxylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.200228
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63666
envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.189539
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC11354204-JCB_202308099_TableS1.xlsx-TFEB-Flag_IP-Protein_name_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31873
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.955401
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	3.62317
Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.54066
FTC133	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16477
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Chromosome 1p36 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872946
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10384
ARID3A_02_193	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.42626
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13858
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
growthlinked	GeneRIF Biological Term Annotations	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.77859
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0047
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28923
1p36 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19545
KIF5C	Pathway Commons Protein-Protein Interactions	1.0	null
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12157
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892714
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5180-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23198
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72331
JOSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03345
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825704
Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.924072
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.923129
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91755
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14706
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.37807
GTEX-S32W-1126-SM-4AD5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93413
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7556
ALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12052
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62707
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23612
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870575
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931113
HCC1187	CCLE Cell Line Gene Expression Profiles	1.0	1.36022
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
RPS11	Pathway Commons Protein-Protein Interactions	1.0	null
CODAS syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847357
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31138
HCC2935	DepMap CRISPR Gene Dependency	1.0	2.18188
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11223
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MORCPR	CCLE Cell Line Gene CNV Profiles	1.0	1.71066
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02612
NO10	DepMap CRISPR Gene Dependency	1.0	2.27521
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30364
VPS26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11809
MORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69927
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87688
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00598
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69969
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94742
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72801
CSE1L	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07183
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51116
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17492
Ectoplacental cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
AP1B1	Pathway Commons Protein-Protein Interactions	1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98404
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15515
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991353
precuneus, right, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868528
Brain Lower Grade Glioma_LGG_TCGA-TM-A84C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27711
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
irritable bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.280796
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10322
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.954078
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.0897
TXNL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33368
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06133
LN428	CCLE Cell Line Gene Expression Profiles	1.0	1.69276
HUG1N_STOMACH	CCLE Cell Line Proteomics	1.0	2.17586
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7391
PPT1	Pathway Commons Protein-Protein Interactions	1.0	null
BT549_BREAST	CCLE Cell Line Proteomics	1.0	10.8235
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56079
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.51067
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle organization	GO Biological Process Annotations 2025	1.0	null
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62404
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96804
hsa-miR-3175	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
EVSAT	CCLE Cell Line Gene CNV Profiles	1.0	1.8384
PSMD6	Pathway Commons Protein-Protein Interactions	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DLST	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.51876
GTEX-X15G-1626-SM-3NMB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38441
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OX-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.5075
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235167
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058597
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41303
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054741
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91223
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47248
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57483
syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055471
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06109
hsa-miR-1972	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
EIF4G3	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24713
PHKG2	Pathway Commons Protein-Protein Interactions	1.0	null
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.792
GPATCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62374
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63844
ATP5MC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58589
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35399
LPCAT1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.00951
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944924
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36297
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
GFPT1	Pathway Commons Protein-Protein Interactions	1.0	null
ESR1	Pathway Commons Protein-Protein Interactions	1.0	null
PTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11385
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
ATP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
HB1119	DepMap CRISPR Gene Dependency	1.0	4.97131
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52462
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16709
hsa-miR-1	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059105
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870947
Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1797
colon_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.859196
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65834
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POGLUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80027
Perturb_14089_KO_SMARCA2_SRP295674	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958242
RXRA	ENCODE Transcription Factor Targets	1.0	null
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.32366
ANAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20518
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15117
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942163
NB10	DepMap CRISPR Gene Dependency	1.0	11.9108
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00009
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34297
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825704
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.72355
EZH2	ENCODE Transcription Factor Targets	1.0	null
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.296194
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Behr syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
LEPROT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18327
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975744
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955988
RPS20	Pathway Commons Protein-Protein Interactions	1.0	null
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.969434
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835333
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824333
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2321
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.811
FAF2	Pathway Commons Protein-Protein Interactions	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27542
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic growth retardation	MGI Mouse Phenotype Associations 2023	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
FAM49A	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06322
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087147
AP3B1	Pathway Commons Protein-Protein Interactions	1.0	null
SNU182	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54486
Immunodeficiency 44	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
NQO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53332
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.41899
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31029
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20487
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882903
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66758
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
UBA7	Pathway Commons Protein-Protein Interactions	1.0	null
SKMEL5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49453
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25928
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825991
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11155
midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243605
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75738
RFWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39708
SNRPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45633
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03717
KIAA0196	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06304
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6032
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01697
SURF4	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11773
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10448
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34362
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834935
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14919
ADK	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.84648
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83612
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879091
TUBB4A	Pathway Commons Protein-Protein Interactions	1.0	null
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.37321
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30055
SLC7A5	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4537	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832224
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948045
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04842
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	1.19835
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899621
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.61768
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
FAR1	Pathway Commons Protein-Protein Interactions	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.47948
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Combined oxidative phosphorylation deficiency 31	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
ITGB2	Pathway Commons Protein-Protein Interactions	1.0	null
PLA2G7	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4617-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34577
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
unknown	GeneRIF Biological Term Annotations	1.0	null
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFKL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991769
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69282
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16865
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09722
IARS	Pathway Commons Protein-Protein Interactions	1.0	null
FDFT1	Pathway Commons Protein-Protein Interactions	1.0	null
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07784
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03507
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6796-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5010-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91158
CCNB1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21291
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51325
5637	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86097
Polyhydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01657
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38959
WDR77	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.903146
D-247MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18729
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968455
RGS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52165
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39299
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58748
UQCRC2	Pathway Commons Protein-Protein Interactions	1.0	null
MCM4	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13764
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.96132
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92218
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855177
MTSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79961
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2574
DNM3	Pathway Commons Protein-Protein Interactions	1.0	null
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058872
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.172291
HS751T	CCLE Cell Line Gene Expression Profiles	1.0	1.36208
HS936T	DepMap CRISPR Gene Dependency	1.0	5.73504
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17984
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049216
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49498
SNPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09897
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933421
Lung squamous cell carcinoma_LUSC_TCGA-58-A46L-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-hREPC_AND_AF_MSC_AND_UM51_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SW1116	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5454
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22712
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12832
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057702
FAM129A	Pathway Commons Protein-Protein Interactions	1.0	null
SLC3A2	Pathway Commons Protein-Protein Interactions	1.0	null
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837576
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43887
Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATL3	Pathway Commons Protein-Protein Interactions	1.0	null
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.47423
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43623
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8041-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC316	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14796
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85383
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26441
embryonic lethality between implantation and placentation, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
PTCD3	Pathway Commons Protein-Protein Interactions	1.0	null
HSPBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23845
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865389
CDK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03474
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39662
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930896
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03415
PSMD13	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS35	Pathway Commons Protein-Protein Interactions	1.0	null
ALAD	Pathway Commons Protein-Protein Interactions	1.0	null
AIMP1	Pathway Commons Protein-Protein Interactions	1.0	null
since	GeneRIF Biological Term Annotations	1.0	null
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61163
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
sex differentiation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.141598
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30382
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17643
stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394197
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50266
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
MED17	Pathway Commons Protein-Protein Interactions	1.0	null
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986659
HOP-92	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATP1A1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85797
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85895
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866635
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88795
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6442
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.836294
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06566
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74718
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50297
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32229
atp binding	GO Molecular Function Annotations 2015	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09772
GATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2694
rectum	HPA Tissue Gene Expression Profiles	-1.0	-0.979834
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
FAM105A	Pathway Commons Protein-Protein Interactions	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.287235
CPSF6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.094
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.812309
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGAP4	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843853
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88094
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
TPRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42388
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23638
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40764
IPO5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33129
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69484
DDOST	Pathway Commons Protein-Protein Interactions	1.0	null
Clitoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956299
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02442
Syndromic X-linked intellectual disability Najm type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
FGFR3_KD_GSE41035_77_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SIMA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40463
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43964
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10716
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.92329
NCSTN	Pathway Commons Protein-Protein Interactions	1.0	null
failure to gastrulate	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
DNER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19625
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970128
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02082
BFTC909	DepMap CRISPR Gene Dependency	1.0	4.09731
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888259
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34234
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	1.72915
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868689
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08221
DNAJC9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DARS	Pathway Commons Protein-Protein Interactions	1.0	null
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3962
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.99997
Charcot-Marie-Tooth disease type 2A2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39938
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GS-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94623
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39752
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56023
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909154
hsa-miR-744	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964149
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045089
OLA1	Pathway Commons Protein-Protein Interactions	1.0	null
KURAMOCHI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
decreased circulating HDL cholesterol level	IMPC Knockout Mouse Phenotypes	1.0	null
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38112
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28982
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938649
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62585
EXOSC4	Pathway Commons Protein-Protein Interactions	1.0	null
Autosomal recessive spinocerebellar ataxia 30	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46299
ABCC5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC25A12	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868689
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844911
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848068
VDAC2	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUL4A	Pathway Commons Protein-Protein Interactions	1.0	null
IMMT	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EK-01A-22R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.959938
POLR2A	ENCODE Transcription Factor Targets	1.0	null
LRRC8C	Pathway Commons Protein-Protein Interactions	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.10389
hsa-miR-519a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
JEKO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.40153
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36752
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4569
CAPZA1	Pathway Commons Protein-Protein Interactions	1.0	null
DNAJA2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z2-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824445
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31654
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
miR-124_OE_GDS2657_770_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24973
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97507
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02657
Lung adenocarcinoma_LUAD_TCGA-MP-A4SW-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFXN3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831605
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30098
WM115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53626
EEF1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30046
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11591
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.61309
Autosomal dominant severe congenital neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
SF3A1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.30883
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4628
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03852
Perturb_9730_KD_SRP55_SRP106195	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.5229
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957453
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.72002
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.842893
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31239
Lung-type ii pneumocyte	Tabula Sapiens Gene-Cell Associations	1.0	13.752
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828024
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21908
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.88143
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64949
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	0.951159
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
PL4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66505
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT10	Pathway Commons Protein-Protein Interactions	1.0	null
nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.205399
ALDH1L2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53417
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02504
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039581
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16606
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Spondylometaphyseal dysplasia Megarbane-Dagher-Melike type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77432
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.39909
NCOR1	Pathway Commons Protein-Protein Interactions	1.0	null
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.121
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.662609
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5025
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832225
ZBTB33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04937
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56158
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30168
Pontocerebellar hypoplasia type 1D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
PLS3	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41612
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05169
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09842
lymphopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166095
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.70621
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38743
CAND1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-34c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
IPO8	Pathway Commons Protein-Protein Interactions	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39814
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22419
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03799
ATP2B4	Pathway Commons Protein-Protein Interactions	1.0	null
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30183
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881064
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12756
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55125
HSP90AA4P	Pathway Commons Protein-Protein Interactions	1.0	null
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92393
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12905
EIF3B	Pathway Commons Protein-Protein Interactions	1.0	null
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	6.49759
abnormal ectoplacental cone morphology	MGI Mouse Phenotype Associations 2023	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	5.98435
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928053
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48373
FKBP8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986779
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43611
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00911
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05566
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03201
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96365
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.917144
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055858
Optic atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.089
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03616
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32399
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.82965
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.608669
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-3.48563
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10748
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41255
PMC10039511-12864_2023_9238_MOESM1_ESM.xlsx-FOXO1_group-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Trachea-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.020321
Charcot-Marie-Tooth disease X-linked recessive 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02515
LCP1	Pathway Commons Protein-Protein Interactions	1.0	null
BECN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26138
ESS1	DepMap CRISPR Gene Dependency	1.0	8.1267
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09494
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00184
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17992
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.920071
LPCAT2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900739
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20951
KINGS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7479515-mmc4.xlsx-ST-RELA-variable-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
PSMC3	Pathway Commons Protein-Protein Interactions	1.0	null
PRR4	Pathway Commons Protein-Protein Interactions	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84252
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0802
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3495
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18711
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05686
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058817
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24704
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP1A3	Pathway Commons Protein-Protein Interactions	1.0	null
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
JJN3	DepMap CRISPR Gene Dependency	1.0	2.17466
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48358
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2426
therefore	GeneRIF Biological Term Annotations	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COPG2	Pathway Commons Protein-Protein Interactions	1.0	null
EIF4G1	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47163
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65091
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881064
CAL78	DepMap CRISPR Gene Dependency	1.0	4.35496
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18792
NDUFS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE119978,GSE180930_0_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6128
ELMO2	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF282	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57312
3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80463
PLEKHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48207
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08529
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61735
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79867
MYO1E	Pathway Commons Protein-Protein Interactions	1.0	null
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46178
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06474
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2771-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991437
JHH1	CCLE Cell Line Gene CNV Profiles	1.0	1.9735
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44641
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.550187
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLOD1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09908
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44938
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53649
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22014
RPL36AL	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal embryo development	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20363
CAT	Pathway Commons Protein-Protein Interactions	1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00828
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22801
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYLA	DepMap CRISPR Gene Dependency	1.0	4.96472
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932223
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902513
Mitochondrial crista junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
KPNB1	Pathway Commons Protein-Protein Interactions	1.0	null
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69796
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949374
PSMC5	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal extraembryonic ectoderm morphology	MGI Mouse Phenotype Associations 2023	1.0	null
NRIP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2096
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053906
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.934738
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PSMD14	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01458
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.39626
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93891
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04637
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
Pontocerebellar hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.539
Pancreas-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	0.105837
PSMC4	Pathway Commons Protein-Protein Interactions	1.0	null
STUB1	Pathway Commons Protein-Protein Interactions	1.0	null
ESR2	Pathway Commons Protein-Protein Interactions	1.0	null
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053338
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59405
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUL4B	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13715
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.00046
DHCR7	Pathway Commons Protein-Protein Interactions	1.0	null
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076252
ACTN1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15854
COLO668	CCLE Cell Line Gene Expression Profiles	1.0	2.16021
ROS-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WDR44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59812
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4687-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17097
transient cerebral ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.336876
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942244
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19564
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
protein-losing enteropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.632384
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2119
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74227
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30168
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49267
pluricellular	GeneRIF Biological Term Annotations	1.0	null
TUBAL3	Pathway Commons Protein-Protein Interactions	1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3004
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38737
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23615
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47003
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81499
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97464
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25442
TUBB8	Pathway Commons Protein-Protein Interactions	1.0	null
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	0.941478
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2203
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062143
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087147
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05467
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975744
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35338
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.11956
KTN1	Pathway Commons Protein-Protein Interactions	1.0	null
ATP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61597
HCC2814	CCLE Cell Line Gene Expression Profiles	1.0	2.23869
Integral component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.019
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93502
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24092
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56999
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63841
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
MCM6	Pathway Commons Protein-Protein Interactions	1.0	null
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32132
CAPN2	Pathway Commons Protein-Protein Interactions	1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15731
BAG6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14337
DPYSL2	Pathway Commons Protein-Protein Interactions	1.0	null
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16079
NCKAP1L	Pathway Commons Protein-Protein Interactions	1.0	null
SH3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927543
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64488
Acute Myeloid Leukemia_LAML_TCGA-AB-2932-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27319
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21705
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12321844-Supplementaryfile1.docx-0-GTF2IRD2B_GTF2IRD2B	Rummagene Transcription Factor Associations 2026	1.0	null
NPEPPS	Pathway Commons Protein-Protein Interactions	1.0	null
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD12	Pathway Commons Protein-Protein Interactions	1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69619
CRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05845
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32272
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.64946
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888324
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04668
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.00685
NCIH2882	DepMap CRISPR Gene Dependency	1.0	3.94693
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05285
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873587
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29612
TRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10794847-mmc6.xlsx-PIAS1_KD_up-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CPCN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55307
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974206
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.10522
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996681
PMC6718408-41467_2019_11884_MOESM6_ESM.xlsx-TAD_genes_ST-EPN-RELA-Unnamed_4_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior parietal lobule, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05506
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79292
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-0.828473
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57972
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-61	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54465
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.507
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42526
GTEx Lung 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-9.94983
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38688
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CLGN	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24519
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20654
GSE135350_3_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.24392
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57034
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.970332
SLR23	CCLE Cell Line Gene Expression Profiles	1.0	2.0325
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66458
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916804
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31664
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.2803
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	0.830708
CH157MN	CCLE Cell Line Gene Expression Profiles	1.0	2.3009
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78907
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36699
SLC25A13	Pathway Commons Protein-Protein Interactions	1.0	null
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81043
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27962
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070596
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
PPA2	Pathway Commons Protein-Protein Interactions	1.0	null
TNPO1	Pathway Commons Protein-Protein Interactions	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052391
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44428
PSMD3	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03662
Lung adenocarcinoma_LUAD_TCGA-78-7537-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831327
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950496
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20884
LMAN2	Pathway Commons Protein-Protein Interactions	1.0	null
CNOT3	Pathway Commons Protein-Protein Interactions	1.0	null
Combined oxidative phosphorylation deficiency 19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904204
PMC11625982-AJH-100-10-s001.pdf-100-MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
mitochondrial membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.063753
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29714
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRANTA519	CCLE Cell Line Gene CNV Profiles	1.0	1.57144
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95105
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
GARS	Pathway Commons Protein-Protein Interactions	1.0	null
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79704
RPS6KA2	Pathway Commons Protein-Protein Interactions	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.121
DEL	DepMap CRISPR Gene Dependency	1.0	3.58185
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8197
ARHGEF7	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MW-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SERPINH1	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16929
CORL95	CCLE Cell Line Gene Expression Profiles	1.0	1.5411
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1395_BREAST	CCLE Cell Line Proteomics	1.0	4.91889
red-green color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02401
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936969
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051423
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48919
Barth syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84554
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55098
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56799
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Cloacal exstrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24253
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
BIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30552
Vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30443
DDB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07386
ATP6V0A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52663
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30153
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4306	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45125
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905305
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64374
CSDE1	Pathway Commons Protein-Protein Interactions	1.0	null
Spinocerebellar ataxia type 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.71523
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934621
GNAO1	Pathway Commons Protein-Protein Interactions	1.0	null
organelle organization	GO Biological Process Annotations 2023	1.0	null
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	2.20445
3-methylcrotonyl-CoA carboxylase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83894
husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.833223
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213291
MEWO	CCLE Cell Line Gene CNV Profiles	1.0	2.1222
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.338707
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1767
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35572
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55432
NCOA3	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14839
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17956
HAT1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48661
ion binding	GO Molecular Function Annotations 2015	1.0	null
EIF3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56231
Combined oxidative phosphorylation deficiency 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
HAUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66008
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85699
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05029
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951691
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.859389
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CJ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85757
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	233.847
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
SBC5	CCLE Cell Line Gene CNV Profiles	1.0	1.52442
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	3.15408
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.39009
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935246
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2565
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984895
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Optic atrophy 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
PRKACB	Pathway Commons Protein-Protein Interactions	1.0	null
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78687
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997355
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.442
HEATR3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42178
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
HOXC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81565
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54736
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29384
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.926673
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75293
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918132
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848325
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50668
hsa-miR-4752	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PABPC4	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6623-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88878
NRD1	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3251
ZNF384	ENCODE Transcription Factor Targets	1.0	null
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34423
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045315
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08448
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6867
SERPINB8	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4419a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	1.0	0.862305
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.074
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
ACE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52328
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57004
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75534
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.16568
NCI-H596	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPS6	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-518a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72514
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04343
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.924396
extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124742
abnormal proximal-distal axis patterning	MGI Mouse Phenotype Associations 2023	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.121
Harel-Yoon syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.987
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06669
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88773
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1411
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49858
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98969
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826748
Cardiomyocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46127
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893405
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26474
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32606
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64462
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS15	Pathway Commons Protein-Protein Interactions	1.0	null
GALK1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5802
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0986
Expressive language disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
PHKA1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18323
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.62771
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.113
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05575
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979924
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846578
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OVMIU	DepMap CRISPR Gene Dependency	1.0	6.70059
chr1_1531013_G_A_b38	GTEx eQTL 2025	1.0	1.20793
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09616
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041547
SC-8023 (IFI16)	NURSA Protein Complexes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75H-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hereditary spastic paraplegia 63	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.827
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIMM50	Pathway Commons Protein-Protein Interactions	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14535
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.18366
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07318
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930353
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046409
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86593
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25204
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8112
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89836
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840383
hsa-miR-5096	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47371
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.183025
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899862
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09976
PYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10015
EFM19	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04576
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13634
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08071
MYLK2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF784	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99361
SNU423_LIVER	CCLE Cell Line Proteomics	1.0	3.53553
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.1344
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.953092
GTEX-SE5C-1326-SM-4BRUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18594
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74363
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49647
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
hepg2	HPA Cell Line Gene Expression Profiles	1.0	0.995821
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07011
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14839
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.992824
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	4.25821
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.918701
Hypomyelinating leukodystrophy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10403
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29185
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06385
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.185
COPA	Pathway Commons Protein-Protein Interactions	1.0	null
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.05935
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824333
GTEX-X4EP-2926-SM-3P5YQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03024
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18142
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08413
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47508
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79087
PMC10039511-12864_2023_9238_MOESM1_ESM.xlsx-LPS_group-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061248
M6PR	Pathway Commons Protein-Protein Interactions	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53922
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.001
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO677	CCLE Cell Line Gene Expression Profiles	1.0	1.56121
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.36321
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56663
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970128
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48612
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTG2	Pathway Commons Protein-Protein Interactions	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.858207
FN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6142
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8653
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47375
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00875
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
FAM49B	Pathway Commons Protein-Protein Interactions	1.0	null
DOCK8	Pathway Commons Protein-Protein Interactions	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.967552
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41327
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21253
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07321
HSP90AB4P	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26956
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43716
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99115
ATF3_02_180	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.30378
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0058
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27976
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.284032
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944924
STOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64437
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963102
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72519
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28851
RPLP0P6	Pathway Commons Protein-Protein Interactions	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44256
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972617
hsa-miR-4654	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01479
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838327
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915603
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42045
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10818
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05042
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83719
Adrenocortical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
EIF4A1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
PACSIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20131
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25737
BUB3	Pathway Commons Protein-Protein Interactions	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.08016
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09908
ZNF648	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68383
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86382
hsa-miR-613	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11579
PABPC5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10196
Axonal neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.118
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27833
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2491
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7902-01A-12R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15919
TPP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07293
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04455
GNAT3	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12277
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97979
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847639
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881064
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54793
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874892
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070672
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35632
ZNF774	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68087
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84073
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51655
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.335412
Pontocerebellar hypoplasia type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.886
DEPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59472
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949445
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
A375SKINCJ3	DepMap CRISPR Gene Dependency	1.0	2.31181
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884667
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
chr1_1456829_G_C_b38	GTEx eQTL 2025	1.0	1.77616
replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.138433
GTEX-XPVG-2026-SM-4B65E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55693
IQSEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63768
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5295
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.987093
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42078
binding	GO Molecular Function Annotations 2015	1.0	null
Cardiac muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 849	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28477
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP15	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
POLD1	Pathway Commons Protein-Protein Interactions	1.0	null
P12-ICHIKAWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZDHHC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18543
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CHD1_02_187	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.97728
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHCR24	Pathway Commons Protein-Protein Interactions	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3812
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69897
NCI-H847	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SEC23B	Pathway Commons Protein-Protein Interactions	1.0	null
IPO7	Pathway Commons Protein-Protein Interactions	1.0	null
dt93	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.851
ALG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52304
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13387
Spastic ataxia 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
MRPS31	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64447
TUBB1	Pathway Commons Protein-Protein Interactions	1.0	null
NOMO1	Pathway Commons Protein-Protein Interactions	1.0	null
DST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42859
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal recessive spinocerebellar ataxia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87662
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.409731
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22581
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57029
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
PLAA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RI1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90015
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-600-ZNF174_ZNF174	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942962
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90409
PSMD1	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14971
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863832
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22705
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38145
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81507
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63867
nes	HPA Cell Line Gene Expression Profiles	-1.0	-1.90115
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	3.08962
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09696
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909773
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847902
LIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10643
Combined oxidative phosphorylation deficiency 52	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78221
AFG3L2	Pathway Commons Protein-Protein Interactions	1.0	null
TIM23 mitochondrial import inner membrane translocase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.133
AATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51002
absent ectoplacental cone	MGI Mouse Phenotype Associations 2023	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052129
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30323
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955399
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54325
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43558
hermaphroditism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.429642
VARS	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrion organization	GO Biological Process Annotations 2023	1.0	null
chr1_1443457_T_C_b38	GTEx eQTL 2025	1.0	1.39206
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36796
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16235
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879634
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79012
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.42903
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19667
abnormal ectoderm development	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.132381
PDIA6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18287
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063559
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831496
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234878
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59138
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98068
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43X-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55232
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
preweaning lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75061
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.893677
Smooth muscle tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73455
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5437
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0887
ACTN3	Pathway Commons Protein-Protein Interactions	1.0	null
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94675
Kidney Chromophobe_KICH_TCGA-KM-8441-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841727
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03596
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945534
Combined oxidative phosphorylation deficiency 43	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastroenteritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.287952
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70447
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JB-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD11	Pathway Commons Protein-Protein Interactions	1.0	null
MTA2	Pathway Commons Protein-Protein Interactions	1.0	null
CPT1A	Pathway Commons Protein-Protein Interactions	1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.8727
LARS	Pathway Commons Protein-Protein Interactions	1.0	null
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10883
NCIN87_STOMACH	CCLE Cell Line Proteomics	1.0	6.85241
EIF3D	Pathway Commons Protein-Protein Interactions	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PARP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02783
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3301
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33207
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47674
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78112
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.18625
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.858207
pancreas	HPA Tissue Gene Expression Profiles	1.0	0.850201
PSMC6	Pathway Commons Protein-Protein Interactions	1.0	null
PELI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7349
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00851
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31673
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CEP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.62654
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05973
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839047
PLS1	Pathway Commons Protein-Protein Interactions	1.0	null
MED4	Pathway Commons Protein-Protein Interactions	1.0	null
QARS	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.915708
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551298
CRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07723
abnormal endoderm development	MGI Mouse Phenotype Associations 2023	1.0	null
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.760318
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829399
Encephalopathy due to defective mitochondrial and peroxisomal fission 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3338
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39874
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.863674
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92985
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90931
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ONECUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36267
SPEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09309
GNAI2	Pathway Commons Protein-Protein Interactions	1.0	null
BHT101	DepMap CRISPR Gene Dependency	1.0	2.09597
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFA4	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919521
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.899553
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05051
IGR37	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92487
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984823
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55826
ATXN10	Pathway Commons Protein-Protein Interactions	1.0	null
AHCY	Pathway Commons Protein-Protein Interactions	1.0	null
ESYT2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958959
hsa-miR-4769-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26868
SF3B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56766
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88919
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80479
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17523
IKBKG	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51208
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32405
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03284
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910995
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90091
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51734
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091061
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070513
hsa-miR-4653-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61087
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847845
TRIM24	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-2426-SM-3MJHL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49321
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01398
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870762
LYZ	Pathway Commons Protein-Protein Interactions	1.0	null
NBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06686
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2911
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79334
ERLIN1	Pathway Commons Protein-Protein Interactions	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5086
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58449
brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.164571
decreased circulating cholesterol level	IMPC Knockout Mouse Phenotypes	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFE2L2_02_174	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.20945
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05071
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846395
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79139
hsa-miR-600	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
small embryonic epiblast	MGI Mouse Phenotype Associations 2023	1.0	null
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80087
protein-dna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070866
atad3	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A4SS-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.458241
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
USE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66545
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896882
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20319
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02834
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61926
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03717
ZC3H15	Pathway Commons Protein-Protein Interactions	1.0	null
SQRDL	Pathway Commons Protein-Protein Interactions	1.0	null
SNU886	DepMap CRISPR Gene Dependency	1.0	2.27335
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22526
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51155
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.41583
SIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67083
Hereditary spastic paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.844
molecular_function	GO Molecular Function Annotations 2015	1.0	null
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67064
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051548
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.03039
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3473
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36702
type ii polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.01387
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901002
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27538
OPLAH	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25599
UBA1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54432
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.164089
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
commensal bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.209583
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS2	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67853
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00159
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32309
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884176
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31221
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01287
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39447
implicated	GeneRIF Biological Term Annotations	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38831
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20716
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887808
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157397
COLO205_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.51778
hsa-miR-3177-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Pontocerebellar hypoplasia type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF521	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81436
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27273
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09458
Anterior horn cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26934
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.50964
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13277
JEG3	DepMap CRISPR Gene Dependency	1.0	4.56821
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATPase, AAA-type, core	InterPro Predicted Protein Domain Annotations	1.0	null
IGR39_SKIN	CCLE Cell Line Proteomics	1.0	5.06518
C1orf210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35584
dna replication factor a complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.212627
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00846
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69176
496100403_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10636
PMC12069319-Table1.xlsx-OCAB_p40_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01458
H4C12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43185
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98636
PMC5932012-41467_2018_4180_MOESM18_ESM.xlsx-Table_19-GSEA_Gene_lists-Zuber_Myb_KD_DN_HUMAN_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCAR2_02_146	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.45943
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76851
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21169
GART	Pathway Commons Protein-Protein Interactions	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03031
SCCPDH	Pathway Commons Protein-Protein Interactions	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF3H	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13346
decreased circulating HDL cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69216
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6442
JPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02358
AAA+ ATPase domain	InterPro Predicted Protein Domain Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00743
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975298
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.88675
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053107
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01591
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43839
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18552
DRG1	Pathway Commons Protein-Protein Interactions	1.0	null
PPP2R2A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993871
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4325
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49428
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6442
Combined oxidative phosphorylation deficiency 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941351
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74649
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61246
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51445
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18273
hsa-miR-4715-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
VCP	Pathway Commons Protein-Protein Interactions	1.0	null
OGDH	Pathway Commons Protein-Protein Interactions	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11799
Lung squamous cell carcinoma_LUSC_TCGA-85-8276-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JIMT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.3398
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257237
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918704
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832809
Lung adenocarcinoma_LUAD_TCGA-62-8397-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46405
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915739
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854797
GNAI3	Pathway Commons Protein-Protein Interactions	1.0	null
GGPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27174
IMPDH2	Pathway Commons Protein-Protein Interactions	1.0	null
SRPR	Pathway Commons Protein-Protein Interactions	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042633
OCIMY7	DepMap CRISPR Gene Dependency	1.0	2.42759
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13539
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07287
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.52705
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24183
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912354
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944924
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO-824	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00313
SNU475	DepMap CRISPR Gene Dependency	1.0	3.04679
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IS-A3K8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.08676
PMC11388079-thnov14p4948s1.pdf-37-IRX3_IRX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33312
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996884
GTEX-QDVN-2226-SM-2S1PM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13014
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060873
ADSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26923
RPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59842
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57187
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0326
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74786
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2965-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02419
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.36704
mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.249664
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51586
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14396
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912949
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3786
GTEX-S4Z8-1226-SM-4AD6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20936
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0851
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948758
Cataract 38	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.70145
ATAD1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U8XE-1826-SM-4E3HV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89814
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	DepMap CRISPR Gene Dependency	1.0	2.73222
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92949
CDC37	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25195
EEF1D	Pathway Commons Protein-Protein Interactions	1.0	null
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1144
AM38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88092
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0028
SRRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28443
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78344
MRPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82781
TIGAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02014
BL373 (TOPBP1)	NURSA Protein Complexes	1.0	null
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064903
Myopathy with extrapyramidal signs	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17001
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H1304	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12069319-Table1.xlsx-OCAB_p35_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.299
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45509
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845299
PPP1CC	Pathway Commons Protein-Protein Interactions	1.0	null
Hak	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
Combined oxidative phosphorylation deficiency 49	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6461
GNA12	Pathway Commons Protein-Protein Interactions	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
PRECLH	CCLE Cell Line Gene Expression Profiles	1.0	1.39337
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91325
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23482
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05398
GNAL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20624
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089868
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.59244
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59387
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72365
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05556
Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tumorigenesis	GeneRIF Biological Term Annotations	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946053
XPO1	Pathway Commons Protein-Protein Interactions	1.0	null
IDH1	Pathway Commons Protein-Protein Interactions	1.0	null
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41109
PC3	CCLE Cell Line Gene CNV Profiles	1.0	1.365
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.42033
DHRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63573
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931229
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
D-423MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895551
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20898
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7461
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86673
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98451
STPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21659
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838846
PPM1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10205
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.944222
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00424
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2464
KMT2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53446
TC32	CCLE Cell Line Gene Expression Profiles	1.0	2.59444
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042743
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12426
chr1_1453552_G_A_b38	GTEx eQTL 2025	1.0	2.52559
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39808
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05588
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.832309
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08651
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23893
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	1.68939
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01082
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42874
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80491
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904347
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476201
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49143
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049727
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.675263
MRPS27	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC43A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9237
SCYL1	Pathway Commons Protein-Protein Interactions	1.0	null
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101026
GXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35831
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67363
TMPO	Pathway Commons Protein-Protein Interactions	1.0	null
ATP2B2	Pathway Commons Protein-Protein Interactions	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.948488
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10494
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860418
KMS28BM	CCLE Cell Line Gene CNV Profiles	1.0	1.40661
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.26709
KHSRP	Pathway Commons Protein-Protein Interactions	1.0	null
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
CTPS2	Pathway Commons Protein-Protein Interactions	1.0	null
BACH1_02_188	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65208
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07755
PMC6855629-pone.0225186.s005.xlsx-Sheet1-DEGs_upregulated_in_the_low_MEIS1_content_thalamus_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31883
preweaning lethality, complete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847118
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
absent extraembryonic ectoderm	MGI Mouse Phenotype Associations 2023	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07873
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984968
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052677
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81638
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1527
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054036
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
PRMT1	Pathway Commons Protein-Protein Interactions	1.0	null
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826638
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.129
MOGS	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4648	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.06
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35146
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34843
TAF15_02_140	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.05889
RERFLCMS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46902
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825704
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934055
hsa-miR-3151	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
jugular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306444
CCDC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01165
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30796
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SART3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36963
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974084
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37436
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.948073
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3-methylglutaconic aciduria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049507
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973469
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.02419
GTEX-S4P3-1326-SM-4AD6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22971
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.270108
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245175
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14364
Adrenocortical carcinoma_ACC_TCGA-OR-A5K4-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52992
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADRBK2	Pathway Commons Protein-Protein Interactions	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992296
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.853911
Lung adenocarcinoma_LUAD_TCGA-55-7281-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HN-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1869
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895339
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88923
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27561
UPF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92235
ZNF511	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31286
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.693446
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25513
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00984
HUWE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97659
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60936
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38304
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24244
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26398
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM15_02_143	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.6845
mitochondrial	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866147
ACLY	Pathway Commons Protein-Protein Interactions	1.0	null
RARS	Pathway Commons Protein-Protein Interactions	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.89016
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22591
PFKP	Pathway Commons Protein-Protein Interactions	1.0	null
ACACA	Pathway Commons Protein-Protein Interactions	1.0	null
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.46036
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.121
MGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80514
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873922
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872243
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984895
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial DNA depletion syndrome 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.47812
external encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.231672
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.989922
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33658
PPP2CB	Pathway Commons Protein-Protein Interactions	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
P-loop containing nucleoside triphosphate hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3811
pulmonary embolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.201308
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884444
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.762199
Kidney renal clear cell carcinoma_KIRC_TCGA-3Z-A93Z-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23238
Perturb_2754_KD_WHSC1L1_ERP011490	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.60468
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04106
KMS12BM	CCLE Cell Line Gene Expression Profiles	1.0	1.52304
organization	GeneRIF Biological Term Annotations	1.0	null
cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.259837
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1004
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10538
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984257
abnormal developmental patterning	MGI Mouse Phenotype Associations 2023	1.0	null
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sapling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29264
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.377621
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839446
CHI3L1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	2.14694
NFE2L1_02_32	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59664
PTPN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26047
ADRBK1	Pathway Commons Protein-Protein Interactions	1.0	null
B3GNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59947
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043654
STAU1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.167611
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
miR-124_OE_GDS2657_771_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04312
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965286
TLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34105
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62004
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858514
androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.460506
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87377
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11257
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83431
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4581
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HT-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Charcot-Marie-Tooth disease X-linked dominant 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14207
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041096
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31663
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75236
coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.167452
quadriceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213833
KMS11	DepMap CRISPR Gene Dependency	1.0	4.41995
NOTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27484
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401765
PSMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61534
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56016
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54628
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14043
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00234
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00062
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
HUH6	CCLE Cell Line Gene CNV Profiles	1.0	1.80004
HCC1897	CCLE Cell Line Gene Expression Profiles	1.0	1.44368
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970128
3-methylglutaconic aciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
ATP2A3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09453
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08922
ILKAP	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4269	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0837
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835817
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31834
Paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.889
NR6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00438
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4481
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.928674
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.42546
ZMPSTE24	Pathway Commons Protein-Protein Interactions	1.0	null
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09085
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SE5C-1026-SM-4BRUG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913601
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905178
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999813
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42041
DNM1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68706
Bronchopulmonary dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
PUS7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8546
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.10606
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68616
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86374
C2CD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42816
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-519c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.694318
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55428
HSP90AB2P	Pathway Commons Protein-Protein Interactions	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.946096
ZNHIT3	Pathway Commons Protein-Protein Interactions	1.0	null
SF1	Pathway Commons Protein-Protein Interactions	1.0	null
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37491
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929266
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969124
TKKK	DepMap CRISPR Gene Dependency	1.0	11.6451
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90996
hsa-miR-1293	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10707
EIF4A2	Pathway Commons Protein-Protein Interactions	1.0	null
OCILY19	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5954
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	4.17677
SLC25A24	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-486-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1818
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957034
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17688
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PABPC3	Pathway Commons Protein-Protein Interactions	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44748
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875125
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34799
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
mitochondrial envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.241716
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15465
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29221
KY821	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1266
GCN1L1	Pathway Commons Protein-Protein Interactions	1.0	null
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05243
PRICKLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45007
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68168
BRE	Pathway Commons Protein-Protein Interactions	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86664
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975744
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.79543
KPNSI9S	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21993
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02166
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57734
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58875
AGPAT5	Pathway Commons Protein-Protein Interactions	1.0	null
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00071
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890154
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75243
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28773
RPS18	Pathway Commons Protein-Protein Interactions	1.0	null
PAICS	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_5_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40747
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13138
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.29319
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54941
ATP1A4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PTK2B	Pathway Commons Protein-Protein Interactions	1.0	null
POLR1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22536
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
GMPS	Pathway Commons Protein-Protein Interactions	1.0	null
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8065
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PC-14 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843624
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
pontine reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882674
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5407
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968105
RNH1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01218
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TECR	Pathway Commons Protein-Protein Interactions	1.0	null
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
SUPT11	CCLE Cell Line Gene CNV Profiles	1.0	1.50178
Perturb_2604_OE_SEPTIN9_SRP159553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.25413
pelvis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315498
Perturb_626_KD_CCND3_SRP325057	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.8379
RPS6KA3	Pathway Commons Protein-Protein Interactions	1.0	null
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083146
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28113
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33851
COLO205	DepMap CRISPR Gene Dependency	1.0	2.10759
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04254
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.878006
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2305
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859957
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	3.21007
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42655
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35652
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16228
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SA-A6C2-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_10_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85746
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03114
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACOT8	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD7	Pathway Commons Protein-Protein Interactions	1.0	null
U251MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54603
replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.138311
hsa-miR-519b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4453	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Combined oxidative phosphorylation deficiency 34	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.3574
CTPS1	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969358
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21987
UBE3C	Pathway Commons Protein-Protein Interactions	1.0	null
DAP3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3191	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.95863
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
APEH	Pathway Commons Protein-Protein Interactions	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.792293
hsa-miR-185	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940474
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22058
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09586
EIF3F	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4767	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02859
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1646
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26383
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098138
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
SH2D2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86382
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04999
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29958
Rectum adenocarcinoma_READ_TCGA-EI-6514-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.35194
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVN-0626-SM-2I3FP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943094
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63687
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4456
PMC12179083-Table_6.xlsx-VCF_Variants_Master_File-Gene_symbol_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
ID1_01_118	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.02947
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mitochondrial crista	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.264
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
superior frontal gyrus, right, medial bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.988881
MYO1F	Pathway Commons Protein-Protein Interactions	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331927
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09854
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075917
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03744
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
Charcot-Marie-Tooth disease type 2A2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960784
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01617
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.883403
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85994
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34103
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02894
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09837
FJX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3531
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.976933
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059592
ATP2B3	Pathway Commons Protein-Protein Interactions	1.0	null
OCILY18	DepMap CRISPR Gene Dependency	1.0	2.21363
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21662
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDE6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.451
KIF5A	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42041
abnormal trophectoderm morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14471
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28249
DNAJA1	Pathway Commons Protein-Protein Interactions	1.0	null
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41738
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.307
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894839
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07011
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9343
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29256
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
UBTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87953
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.55056
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08583
CORL23	DepMap CRISPR Gene Dependency	1.0	4.39621
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
thyroid	GTEx Tissue Gene Expression Profiles	1.0	0.925622
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31244
SLC1A5	Pathway Commons Protein-Protein Interactions	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
PDHB	Pathway Commons Protein-Protein Interactions	1.0	null
leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.091656
496100565_FWM_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2044
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092982
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39581
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FB-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846363
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16984
HSP90AA2	Pathway Commons Protein-Protein Interactions	1.0	null
HCC-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CARS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09708
Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959531
F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19631
GTEX-RUSQ-0926-SM-47JWU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982612
ARID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09121
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963178
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4126
DNM1L	Pathway Commons Protein-Protein Interactions	1.0	null
DYNC1H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67025
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0986
ESYT1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2976-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BFTC909	CCLE Cell Line Gene CNV Profiles	1.0	2.48827
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842698
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKBIP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37517
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.980349
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22769
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35418
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.24895
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.877432
SMARCB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13225
MKN74	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69405
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27918
HN	CCLE Cell Line Gene CNV Profiles	1.0	1.64565
ARG1	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967053
RERFGC1B	CCLE Cell Line Gene CNV Profiles	1.0	2.1595
MRPS17	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr1_1472158_C_G_b38	GTEx eQTL 2025	1.0	2.59685
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31138
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33403
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.133633
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	1.44536
leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058662
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851004
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49049
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.870764
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69766
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.834282
ACTB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.891533
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40_02_186	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.75489
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051103
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08549
PDHA1	Pathway Commons Protein-Protein Interactions	1.0	null
OGDHL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08307
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17752
TNPO2	Pathway Commons Protein-Protein Interactions	1.0	null
SNU387	DepMap CRISPR Gene Dependency	1.0	3.65684
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26351
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40832
hsa-miR-4538	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
AARS	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-193b-3p	MiRTarBase microRNA Targets	1.0	null
contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.266774
leprosy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.227297
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39224
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04624
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1464
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926556
Optic atrophy 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
PMC7843730__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Mitochondrial inner boundary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	276.209
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70494
nuclear chromosome part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.067601
H1-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61138
IREB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89297
IPO9	Pathway Commons Protein-Protein Interactions	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12269
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31264
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10594
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.803961
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826893
hsa-miR-4510	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20994
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48564
CYFIP1	Pathway Commons Protein-Protein Interactions	1.0	null
ALDH18A1	Pathway Commons Protein-Protein Interactions	1.0	null
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08004
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11133
karpas707	HPA Cell Line Gene Expression Profiles	1.0	1.09718
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97737
LANCL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242083,GSE242098_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26967
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.53616
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ATP1A2	Pathway Commons Protein-Protein Interactions	1.0	null
YME1L1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66669
RPS6KA1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC95	CCLE Cell Line Gene Expression Profiles	1.0	1.44416
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
JOPACA1	DepMap CRISPR Gene Dependency	1.0	2.06755
RNPEP	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.39102
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GV-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3662
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971424
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989408
Perturb_302_KD_HHEX_SRP405197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.17384
IDH2	Pathway Commons Protein-Protein Interactions	1.0	null
Organic acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
KCTD12	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7983
GSE213228_1_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22944
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824333
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32545
nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.208825
PHKA2	Pathway Commons Protein-Protein Interactions	1.0	null
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859994
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-206	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30798
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-2.32088
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.963847
GNA13	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72436
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843194
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90698
rpmi8226	HPA Cell Line Gene Expression Profiles	1.0	2.71639
wm115	HPA Cell Line Gene Expression Profiles	-1.0	-1.12928
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.927478
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A6-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPIN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24861
SALE	CCLE Cell Line Gene Expression Profiles	1.0	1.76262
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4649-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52353
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987035
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944924
chr1_1445187_T_G_b38	GTEx eQTL 2025	1.0	2.43373
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46173
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24526
L428	DepMap CRISPR Gene Dependency	1.0	3.8136
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828042
HIBADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12265
SCO2	Pathway Commons Protein-Protein Interactions	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.282225
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16949
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93607
PPP1CB	Pathway Commons Protein-Protein Interactions	1.0	null
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56804
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79789
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124514
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56201
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4048
COLO849	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58335
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.7122
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73891
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34846
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870363
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972358
Megalencephalic leukoencephalopathy with subcortical cysts	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
RHOD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05521
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22591
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56555
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.978179
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.46447
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12109
RRM1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13101
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07619
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
IKBKB	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905816
Lung adenocarcinoma_LUAD_TCGA-49-4501-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3968
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3919
Lung squamous cell carcinoma_LUSC_TCGA-90-A59Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C1orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01747
organelle envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.198325