association	dataset	threshold value	standardized value
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09164
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057833
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
chr3_193683232_A_G_b38	GTEx eQTL 2025	1.0	1.59604
hsa-miR-3125	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
KCNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35208
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FASTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20835
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32784
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61598
Perturb_2608_OE_MiR4553p_SRP190040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Gonadal sheath cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.163
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873354
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42227
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06978
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05448
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.29041
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60391
abnormal retina outer nuclear layer morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07435
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8204
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28049
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56214
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49699
HCC2157	CCLE Cell Line Gene Expression Profiles	1.0	2.25281
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.051239
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01201
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
SNU81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91156
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10875
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06264
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04116
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05284
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
METTL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29739
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4162
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80843
chr3_193696692_C_T_b38	GTEx eQTL 2025	1.0	1.07397
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87287
Lung-type i pneumocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.861068
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93831
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841596
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995604
hsa-miR-508-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Periventricular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06706
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52375
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74489
MCF-10A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.75365
METTL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52042
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7203
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68554
GTEX-SIU7-1326-SM-4BRWW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914296
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02594
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69477
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2941
RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9885
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12128
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14606
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28297
hsa-miR-4762-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21649
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40465
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12897
PPP1R3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84351
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.985541
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04814
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69291
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4738-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38862
TRPM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84564
X-linked spinocerebellar ataxia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
SOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09541
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1053
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14681
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45743
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30951
TRABD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69308
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37981
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4975-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
KDM4C_natural variation_GSE41040_589_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68412
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30169
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4739-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0888
Weight Loss	CTD Gene-Disease Associations	1.0	1.30329
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18132
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HCC2935	CCLE Cell Line Gene Expression Profiles	1.0	1.44187
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Parkinson's disease 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22205
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08229
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984312
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	1.69304
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
juvenile-onset Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
CFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25883
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27307
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
early-onset Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52316
early endosome membrane	GO Cellular Component Annotations 2023	1.0	null
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11139
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30564
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34197
UT7	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
GTEX-P4PQ-0526-SM-2HMKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.068
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE250534_0_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_12218_KD_EPRS_SRP073504	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74303
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1054
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5794
SEMA6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46393
ISTMES2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59509
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23545
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.443547
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8805
ZNF750_KD_GSE38039_696_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875629
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ion channel transport	Reactome Pathways 2024	1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3152
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.33254
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908443
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78058
ATMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68493
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7139
ARHGEF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86647
GSE173997_1_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Major depressive episode treated with electroconvulsive therapy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
Hydranencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
GSE180631_1_v_0_yap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07124
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77618
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92628
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68588
Perturb_186_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.57737
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07343
GSE200839,GSE233826_2_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.272
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48889
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0128
catenin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.594753
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29394
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35651
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18086
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
GTEX-SIU7-0526-SM-3NM8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967859
GTEX-XPT6-0426-SM-4B672	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854234
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7822-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GMNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60919
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83479
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6756
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29098
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	5.95438
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96252
pc3	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.055913
Rectum adenocarcinoma_READ_TCGA-F5-6864-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular cation homeostasis	GO Biological Process Annotations 2015	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.666434
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28662
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31696
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01485
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238706
hsa-miR-107	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53892
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39129
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7732
HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CAAX-protein geranylgeranyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.753
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71292
GSE200839,GSE233826_2_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.873448
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22389
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47316
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863019
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4257
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69747
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0457
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13487
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833688
NAMPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38689
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0963
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61453
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44856
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983567
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36847
chr3_193584507_T_A_b38	GTEx eQTL 2025	1.0	4.22843
Genomic Instability	CTD Gene-Disease Associations	1.0	1.06442
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04594
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62598
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32092
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00305
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03461
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0245
disease	GWASdb SNP-Disease Associations	1.0	0.027381
MIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88608
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.847541
Perturb_3445_OE_Sca17_SRP248035	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.29913
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22243
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88362
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56897
PMC6538374-elife-45672-supp3.xlsx-DEGs-Genes_expressed_at_lower_levels_in_SMARCB1_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LGALSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63718
MYLK_knockdown_49_GSE14525	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	4.59857
GSE99112_0_v_1_upf3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910369
GTEX-S4Z8-0326-SM-3K2AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37113
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2602
Lung adenocarcinoma_LUAD_TCGA-49-4501-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90751
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853119
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876032
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27792
GSE173262_6_v_4_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Progressive non-fluent aphasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
PRR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40824
A-Vietnam-1203-2004(H5N1)_2day-wtC57BL-6J_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.15497
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.966682
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08076
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
lung	GTEx Tissue Gene Expression Profiles	1.0	1.08316
YDJC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2559
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27574
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93405
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUGC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91472
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836125
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
HMX1_Deficiency_GDS4810_324_mouse_Retinas of C57BL/6J	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18954
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97515
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58012
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fenofibrate_homo sapiens_gpl4044_gse15494	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862281
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42083
TOX_01_332	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.68648
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.749908
intermediate stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00817
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9956
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02496
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.17
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17866
TNFAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02898
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22075
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_185_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.51474
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-OTX1_OTX1	Rummagene Transcription Factor Associations 2026	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3969
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59011
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900067
Chromosome 18p deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
ATN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37464
Recycling endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042148
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.825602
delay	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877236
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27448
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88773
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53787
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02869
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.02357
ZDHHC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00998
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.461
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09957
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33262
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37347
epilepsy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.610057
FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
COCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98995
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCC021	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896365
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14301
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.88836
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03273
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900231
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.201707
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68199
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2885
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80257
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
atpase activity	GO Molecular Function Annotations 2015	1.0	null
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40383
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.31778
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.197
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
TE9	CCLE Cell Line Gene Expression Profiles	1.0	1.60778
NB10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UOK101	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6139
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cellular divalent inorganic cation homeostasis	GO Biological Process Annotations 2015	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40604
cellular chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0329
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.925056
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2405
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16893
POLR1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22536
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81242
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04156
PITHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5925
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19875
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3783
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54074
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00418
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0174
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17223
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_UP-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58907
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94223
Distal arthrogryposis type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37492
GSE127252_2_v_3_sulforaphane_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CMK86	CCLE Cell Line Gene Expression Profiles	1.0	2.08768
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
LYPLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60981
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33686
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBK-0425-SM-3LK5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47894
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45485
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919572
MEGF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19214
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97908
Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Mouth disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15646
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25005
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cellular metal ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Perturb_9622_OE_Mir155_SRP295675	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.13552
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20928
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23724
GSE111102,GSE111105_3_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.9989
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-1526-SM-3NB1J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11946
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10441
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_18400_KO_Wnk1_SRP247391	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.8144
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20769
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32283
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924489
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82954
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918022
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72004
SLC66A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18322
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96508
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23738
homeostatic process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24163
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4725
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53653
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34031
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39897
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25281
Perturb_13490_KD_Ncor1_ERP132013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBEW-1426-SM-4AT4J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18971
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97257
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51978
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0469
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964085
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E7-01A-31R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54296
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17743
GJD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94398
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34958
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28047
organelle part	GO Cellular Component Annotations 2015	1.0	null
Anaplastic large cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68465
PMC9170110-pgen.1010161.s046.xlsx-DEP_DBP-nearestGene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23021
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055343
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HI-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23545
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4PP-3026-SM-3P61O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910172
RB1_KD_GSE50532_624_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22625
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8486
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1525
ROS50	DepMap CRISPR Gene Dependency	1.0	3.30848
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14883
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75424
CAL-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1419	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30908
Fiddlehead	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
CDK11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19507
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51797
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15876
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A905-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95286
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CD1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64559
spleen_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.863074
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.969372
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22341
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7133
Fatty Liver	CTD Gene-Disease Associations	1.0	1.12838
PACADD119	DepMap CRISPR Gene Dependency	1.0	4.74795
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833248
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15277
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26429
KYO1	DepMap CRISPR Gene Dependency	1.0	2.20072
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17995
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25214
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53892
Lassa Fever Virus_8hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.00238
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841239
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897381
GTEX-QDVN-0626-SM-2I3FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31772
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08158
chr3_193585263_CA_C_b38	GTEx eQTL 2025	1.0	1.09366
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855438
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
PBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61513
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26511
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914818
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267791
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19334
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983491
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7281
metal ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0142
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4544
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95649
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02533
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38682
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44886
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82524
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87933
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46944
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_13309_OE_Mir143_SRP106683	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1667
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25392
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97575
PMC11378415-12943_2024_2100_MOESM6_ESM.xlsx-CopyNumberGain_ExpDown-GRHL1_GRHL1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4693-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50086
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977687
Astrocyte_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3916	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28322
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
RNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57266
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44359
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10121
single-organism transport	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TQ-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP5MJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.289
PLAGL2_deficiency_GDS3010_139_mouse_embryonic small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01479
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36761
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34724
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76821
PLCPRF5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34989
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876435
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926431
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21075
Endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60526
endometrium_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.878927
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48856
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4969
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38862
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864026
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53648
GTEX-XGQ4-2226-SM-4AT4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27224
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.47147
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849809
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.84242
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14066
PPRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65122
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950557
Lung adenocarcinoma_LUAD_TCGA-67-4679-01B-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883636
EFHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62874
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16228
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43942
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4760-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10260405-41588_2023_1409_MOESM6_ESM.xlsx-ST12-Supplementary_Table_12_Most_likely_causal_genes_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.988814
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972696
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32131
Early endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95203
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62333
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56629
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1809
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32058
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42806
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81219
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.957418
Atrophy	CTD Gene-Disease Associations	1.0	1.14919
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23724
KIAA0319L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87175
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02804
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863593
GTEX-S32W-0326-SM-2XCBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862843
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JVE015	DepMap CRISPR Gene Dependency	1.0	4.07615
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5181-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
PTP4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52834
ZNF623	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52461
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
GTEX-TKQ1-0226-SM-33HB5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919262
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68926
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68869
OAW-28	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
Astrocyte_Embryonic prefrontal cortex_Human	CellMarker Gene-Cell Type Associations	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.17959
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55773
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.858277
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13577
all	GWASdb SNP-Phenotype Associations	1.0	0.030258
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04379
DENND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91305
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9008
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09258
POLR2G_02_130	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.07039
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.142
NFATC1_02_22	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.22239
HCC70	CCLE Cell Line Gene Expression Profiles	1.0	1.52712
HCFC1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14245
Autism	DisGeNET Gene-Disease Associations	1.0	null
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34179
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38289
hsa-miR-3605-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Hyperekplexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
NEDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19907
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03326
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
PAGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95734
MYSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15671
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057345
Specific language impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.307
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05028
PRPSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54208
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07139
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30525
SRSF7_02_133	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.45943
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03383
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213471
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.730571
cancer	GWASdb SNP-Disease Associations	1.0	0.039374
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
FBXO31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36319
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.70716
TCEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70216
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57167
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961544
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66584
Perturb_11872_KO_lincRNACox2_SRP120127	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.8177
ACVR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62299
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Multilymphoid progenitor cell_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dihydropyrimidinase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82137
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84727
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40632
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.5634
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CAV3_KO_GDS3533_357_mouse_mammalian glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SRSF7_02_02	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.0
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948901
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16042
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42452
Cation-transporting P-type ATPase, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X8HC-0226-SM-4E3K1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05328
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80264
P-type ATPase, A  domain	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.062
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09219
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3112
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929684
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07117
chr3_193637313_T_C_b38	GTEx eQTL 2025	1.0	1.13836
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56137
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Glycinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
Pancreatic Neoplasms	dbGAP Gene-Trait Associations	1.0	0.032613
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.37182
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.18915
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939361
LIPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85294
Lung squamous cell carcinoma_LUSC_TCGA-66-2763-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15286
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8276
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903359
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10428
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03698
GTEX-TMMY-1226-SM-4DXT6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28942
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26141
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04977
DEF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17436
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00655
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	2.39783
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049272
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06251
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91023
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880182
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16474
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02048
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08632
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05122
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861613
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17473
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64143
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4856-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00392
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6847
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997461
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31387
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.889046
hsa-miR-616	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Phosphoric acid	HMDB Metabolites of Enzymes	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3275
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25548
Ion transport by P-type ATPases	Reactome Pathways 2024	1.0	null
u698	HPA Cell Line Gene Expression Profiles	1.0	0.829397
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24777
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00523
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07566
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994983
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4LX-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6048
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.847775
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LBH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77006
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32204
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887296
PFKL_OE_GDS1980_203_mouse_dermal fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00062
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932518
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
ACSL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47243
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21585
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VMRC-MELG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
karpas707	HPA Cell Line Gene Expression Profiles	1.0	1.1074
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.30234
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFAND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57956
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31112
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24603
Middle frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
NALM19	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
SNU1214	CCLE Cell Line Gene Expression Profiles	1.0	1.57296
SFRP5_KO_GDS4988_27_mouse_gonadal white adipose tissue HFD	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CEBPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47669
JOSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59407
Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MG-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48283
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3367-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16833_Mut_Runx3_SRP349093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.1606
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96016
NCI-H1648	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
PAPOLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22373
NCIH1781	CCLE Cell Line Gene Expression Profiles	1.0	2.08665
ONS76	DepMap CRISPR Gene Dependency	1.0	5.6942
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02149
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66368
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03953
KP-N-RT-BM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082335
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
Lung-club cell	Tabula Sapiens Gene-Cell Associations	1.0	1.7282
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994983
PI4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70991
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94761
Lysosomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02173
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF570	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58983
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12538
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central core myopathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TOP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4309
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28151
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13883
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.05999
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.27217
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52553
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-596	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10831
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.114
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22648
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16849
intracellular calcium ion homeostasis	GO Biological Process Annotations 2025	1.0	null
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31512
SUCLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52606
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9261
ADGRG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79734
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1836	DepMap CRISPR Gene Dependency	1.0	4.77385
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02603
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01015
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914588
Clitoral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
Neuronal ceroid lipofuscinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
GSE172020_1_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16347
hsa-miR-3686	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
U2AF1_02_165	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-05A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.890488
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
endoplasmic reticulum part	GO Cellular Component Annotations 2015	1.0	null
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19464
A-CA-04-2009(H1N1)MA_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.61226
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047114
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00188
CHCHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65194
C2CD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54406
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9917
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39368
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0501
Perturb_11488_KO_Foxp1_SRP158103	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.44673
HMMR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26678
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
early endosome	GO Cellular Component Annotations 2025	1.0	null
interrupted	GeneRIF Biological Term Annotations	1.0	null
CASKI	DepMap CRISPR Gene Dependency	1.0	3.13712
H2AC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29913
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945177
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.753
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55859
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	1.62054
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06638
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55018
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF785	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27319
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897381
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56578
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11823
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1624
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20588
PMC12820306-41598_2025_32262_MOESM1_ESM.pdf-198-ZNF385B_ZNF385B	Rummagene Transcription Factor Associations 2026	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21633
Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0426-SM-46MUK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17102
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75169
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63315
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28993
ZNF750_KD_GDS4599_177_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SNU886	DepMap CRISPR Gene Dependency	1.0	2.94896
SNU489	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59655
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45266
HCC364	CCLE Cell Line Gene Expression Profiles	-1.0	-2.037
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08811
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76655
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883636
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50124
Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16495
Obsession score in obsessive compulsive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1292
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.75447
APLN_KO_GDS3228_601_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23003
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98718
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.265757
C99	DepMap CRISPR Gene Dependency	1.0	4.16639
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
RDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35423
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15077
Orbital area, ventrolateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1174
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06766
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.888438
OVCA433	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76027
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.047698
calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.340906
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865224
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.985541
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KBTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94541
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3127
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.046232
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89115
CA46	CCLE Cell Line Gene Expression Profiles	1.0	1.35715
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78889
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973647
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967708
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884946
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20946
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43667
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2914
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
RUNX1	ChEA Transcription Factor Targets	1.0	null
CCDC106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85516
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02077
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01519
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35813
hsa-miR-1324	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69979
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02443
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
PHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27313
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951878
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78608
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29212
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.1484
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X-linked cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
ASF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24605
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08627
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F2-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71699
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.199032
GSE212628_2_v_5_mier1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11913834-Table2.xlsx-CEBPB_bound_geneset-Gene_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02286
GTEX-REY6-2426-SM-48FF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62915
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2206
ELMOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50092
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06491
NCIH1930	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49811
RBM15_02_171	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.58496
GSE164494_0_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27922
lateral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35462
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
Prostate adenocarcinoma_PRAD_TCGA-CH-5737-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895867
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01491
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952897
GTEX-W5WG-1426-SM-4KKZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19049
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21208
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10782
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32263
Cerebellar ataxia, mental retardation and dysequlibrium syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11394
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29212
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60101
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8515-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01001
lung_3f	HPA Tissue Sample Gene Expression Profiles	1.0	1.09842
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
SAP30L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91505
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6376
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
SEMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07546
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13506
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88706
cation binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_12141_KO_Lgals9_ERP122370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.1347
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26919
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
EVI5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59448
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09711
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9603
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13837
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14344
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35736
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.79202
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37467
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20573
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.672202
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5378-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67245
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56059
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2183
FBXO41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06516
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7385-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08401
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50567
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64517
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857352
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9286
ALDH5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13697
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26647
Orbital area, lateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00521
Early endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03749
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.096092
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93834
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.10326
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83765
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72461
SNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0911
UBE2Z	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8093
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06045
ANXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05329
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.51422
PMC12433928-12672_2025_2985_MOESM1_ESM.pdf-11-RUNX2_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48064
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.30844
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
nucleoside-triphosphatase activity	GO Molecular Function Annotations 2015	1.0	null
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05978
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863615
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19508
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90905
MEIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92785
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38603
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46131
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4074
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.449
SNCA_KO_GDS4153_528_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HES4	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	1.68996
RMUGS	DepMap CRISPR Gene Dependency	1.0	2.57858
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02647
Fibrosis	CTD Gene-Disease Associations	1.0	1.63317
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52374
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.524
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02697
PCBP2_02_135	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.12928
EM2	DepMap CRISPR Gene Dependency	1.0	6.83631
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2821
SLC39A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42142
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24381
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31559
calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.717232
cation homeostasis	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4410-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung-type ii pneumocyte	Tabula Sapiens Gene-Cell Associations	1.0	12.7202
layer 4 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25422
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38229
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.63369
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
divalent inorganic cation homeostasis	GO Biological Process Annotations 2015	1.0	null
KMT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86755
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8004
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.899926
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1583
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03407
UST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90192
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.55835
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.5573
PREB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51965
Combined oxidative phosphorylation deficiency 23	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63219
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40801
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.15661
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
POMC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35844
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22361
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4502
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25171
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4081
pyrophosphatase activity	GO Molecular Function Annotations 2015	1.0	null
Nucleolus organizer region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
recycling endosome membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11765
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55698
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2462
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.36174
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63227
Posterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
PMC6687946-hmg-2019-d-00137_bugiardini_r1_supplementary_table_s1_ddz093.xlsx-Supplementary_table-Supplementary_Table_S1_List_of_rare_MAF_0_01_genetic_variants_found_with_Trio-based_analysis_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
Mouth	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926275
GTEX-U3ZM-0426-SM-3DB73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923179
hsa-miR-555	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SMURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90719
language	GeneRIF Biological Term Annotations	1.0	null
Adenosine triphosphate	HMDB Metabolites of Enzymes	1.0	null
CD47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32753
MAFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.585
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20959
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-11A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
insular cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43611
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12274
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Velum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.747
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
calcium ion homeostasis	GO Biological Process Annotations 2023	1.0	null
SW1990	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32887
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01417
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.9239
GSE139120_1_v_0_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60371
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984312
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MACF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53115
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30612
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94505
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04936
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A51Y-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29635
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21357
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0373
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10046
GSE206400_3_v_4_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95905
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21531
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13647
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13837
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1173
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97601
CTHRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39933
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55485
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21318
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
ZDHHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5661
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883636
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ERI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15483
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20959
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
SHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69478
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15669
18614019-TableS4d	GeneSigDB Published Gene Signatures	1.0	null
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_9_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857206
tongue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27401
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16985
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.82306
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92521
A172	DepMap CRISPR Gene Dependency	1.0	2.051
telomere-telomerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SPAG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05491
TTYH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31623
JHESOAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61685
ZNF626	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14613
MLST8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88516
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983384
PBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66666
RERF-GC-1B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843566
CYRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49589
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73314
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040985
BRCA1_02_202	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1765
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96793
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Dicarboxylic aminoaciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847472
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preopto-hypothalamic band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01868
CAL-85-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89275
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94745
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08246
RERFGC1B	CCLE Cell Line Gene Expression Profiles	1.0	2.40865
Infertility, Female	CTD Gene-Disease Associations	1.0	1.25494
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85958
Sporulated oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81323
RRAGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86196
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inorganic ion homeostasis	GO Biological Process Annotations 2015	1.0	null
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55W-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
P-type ATPase, cytoplasmic domain N	InterPro Predicted Protein Domain Annotations	1.0	null
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25992
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989027
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875048
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8123
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24285
mantle zone of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28958
GTEX-PWN1-2626-SM-2I3FH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06734
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01592
membrane part	GO Cellular Component Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A1L2-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44003
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61V-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19489
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4784-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8914
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65106
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
3-methylglutaconic aciduria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32812
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
abnormality of the pancreas	GWASdb SNP-Phenotype Associations	1.0	0.370686
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40921
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54573
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80672
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18295
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EN1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62743
NB10	DepMap CRISPR Gene Dependency	1.0	8.31588
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94644
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16652
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0043
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.60035
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42013
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13912
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34298
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE164494_0_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ADNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04737
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.18073
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.47147
YAPC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60159
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4776
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888531
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06788
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22357
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3071
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869052
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10163
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5567-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kufor-Rakeb syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
HSPBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23845
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7535
CESS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92597
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36822
Orbital area, medial part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02492
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3558
GSE104022_3_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.01379
GTEX-S4P3-1526-SM-3K2AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877791
intermediate stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03953
KNS81	DepMap CRISPR Gene Dependency	1.0	6.26494
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33837
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895458
DOV13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41688
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0241
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49463
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28048
pancreatic neoplasms	GAD Gene-Disease Associations	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
TTC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40629
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.93647
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20581
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20386
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92089
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21745
pancreatic cancer	GWASdb SNP-Disease Associations	1.0	0.630986
OCI-LY7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CEP170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.019
Perturb_9048_OE_PRRX1B_SRP168742	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.39937
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11753
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977187
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966881
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55404
GSE111247_11_v_9_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95302_1_v_4_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95879
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
chr3_193516137_C_T_b38	GTEx eQTL 2025	1.0	2.8241
SUMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839808
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7068
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22413
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047819
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29875
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962735
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03911
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03895
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48758
NCIH2196	CCLE Cell Line Gene CNV Profiles	1.0	1.49053
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0569
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.01642
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82788
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31829
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47183
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96359
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.974337
RPMI6666	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35435
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21192
TRIM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60757
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
DNA-dependent protein kinase-DNA ligase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.681
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1603
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3227
L3MBTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69782
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95008
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51464
endosome membrane	GO Cellular Component Annotations 2023	1.0	null
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3127
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030299
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23797
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16995
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34172
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01268
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42171
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC49A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20887
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00159
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8314-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57829
HSDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56883
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40773
Lung squamous cell carcinoma_LUSC_TCGA-85-7697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32487
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897381
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19315
2313287	CCLE Cell Line Gene Expression Profiles	1.0	1.55307
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.823961
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07254
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
pancreatic adenocarcinoma	GWASdb SNP-Phenotype Associations	1.0	0.536325
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02854
MACIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32669
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52064
CEBPZ_02_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.73697
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863917
lung	HPA Tissue Gene Expression Profiles	1.0	1.01269
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF687	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84001
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21786
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX1	ChEA Transcription Factor Targets	1.0	null
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34431
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892485
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26298
NMB	DepMap CRISPR Gene Dependency	1.0	5.03138
cellular process	GO Biological Process Annotations 2015	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.896164
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952655
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271604
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907256
F36P	DepMap CRISPR Gene Dependency	1.0	2.96412
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5841
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58054
T98G	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47827
CARNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79548
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.877383
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30955
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11055
GSE241036_4_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
THAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54927
HTC-C3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03779
MFE-280	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17346
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.74441
lung_3e	HPA Tissue Sample Gene Expression Profiles	1.0	1.1241
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51225
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826118
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12997
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39581
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90445
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.9995
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3352-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72336
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08881
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902911
ARHGEF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30083
PMC7725876-Table_2.xls-Sheet1-Table_2_v1_DEGs_in_the_BESC_were_treated_with_LPS_compared_with_PBS_control_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8119
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30988
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51313
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873739
Perturb_184_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.69993
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2413
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980428
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994983
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
MEC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32747
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_16303_KO_Esr1_SRP115139	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0431
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.185309
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-0.985541
ABCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39236
TARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06046
HEV_60Day_None_GSE53731	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.41321
Transcription factor TFIID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
C80	DepMap CRISPR Gene Dependency	1.0	5.8254
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
outer SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07751
20035825-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926019
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.10867
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.038831
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4684
OC314	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5387
PMC3470785-NIHMS377161-supplement-3.pdf-564-ZNF278_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72413
Perturb_12086_OE_Esr1_SRP050547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.78559
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.905116
BB65-RCC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TIGAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94669
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12065_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.090163
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52651
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.515317
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04304
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31276
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
SK-MEL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09213
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11876
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6355
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085353
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23033
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00997
benign epilepsy with centrotemporal spikes	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.5194
TIG3TD	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85117
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27401
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390421
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5453-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-XS-A8TJ-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3360_KO_Bach2_SRP267100	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.40447
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90523
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874675
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.652381
Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endoplasmic reticulum membrane	GO Cellular Component Annotations 2023	1.0	null
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57265
intermediate stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04384
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8158
RAGE_knockout_268_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52891
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04888
Acrokeratosis verruciformis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
hsa-miR-942	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90622
NCI-H810	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852807
Hypertension	CTD Gene-Disease Associations	1.0	1.22853
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5254
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2142
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.939904
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.47147
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86685
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21248
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3127
SLC16A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87007
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06079
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-1126-SM-4BRVS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827152
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.045
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82737
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PABIR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78785
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17639
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27907
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.988848
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13195
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15518
Esophagus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.996471
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45589
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19556
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883636
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854286
Parahippocampal region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
CAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61859
PMC11588066-pnas.2410331121.sapp.pdf-136-BHLHE41_BHLHE41	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32802
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79613
POU3F2	ChEA Transcription Factor Targets	1.0	null
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nonhomologous end joining complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
GTEX-P4PQ-0626-SM-3NMCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863196
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853546
SLC52A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49491
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08576
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92505
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.01776
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07166
Tooth disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4991-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SVIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17533
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
Perturb_10376_KO_Fdft1_SRP285919	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.0183
MOV10L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36432
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-OLIG2-M_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
EWS502	DepMap CRISPR Gene Dependency	1.0	2.96482
RMND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16076
NCI-H1781	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-766	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
L1CAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12821
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072108
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47327
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07215
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12105
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0992
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25546
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	1.0	3.40793
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98237
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11357
GSE210476_9_v_3_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-A4SR-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38862
EIF2AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71722
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78345
ERMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76565
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863062
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6334
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56263
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80241
SAMHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9993
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1456
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921571
MBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10047
Lung-basal cell	Tabula Sapiens Gene-Cell Associations	1.0	2.08427
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.037
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8221
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05483
GPR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22346
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1155
TTC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89846
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00418
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Orbital area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04571
POLR2A	ENCODE Transcription Factor Targets	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	3.12101
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH28	DepMap CRISPR Gene Dependency	1.0	2.24586
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38249
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
Agranular insular area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64726
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38136
TTPAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61453
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04823
HOOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67357
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.63834
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17507
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51593
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.985541
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25566
16651414-Supp3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-S32W-0726-SM-2XCBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75084
hsa-miR-3200-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89321
Primary progressive aphasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Hereditary spastic paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
PFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05981
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3957
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
GSE193685_2_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29705
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873929
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SHPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01081
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0925
extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.390068
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6805
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4267
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95052
endosome membrane	GO Cellular Component Annotations 2025	1.0	null
NOMO1	DepMap CRISPR Gene Dependency	1.0	3.56838
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36087
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0541
endocrine gland cancer	GWASdb SNP-Disease Associations	1.0	0.361946
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38071
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
ATP6V1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68586
cellular homeostasis	GO Biological Process Annotations 2015	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GSE182680,GSE182683_0_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55441
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00107
NR3C1	ChEA Transcription Factor Targets	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055748
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
P-type ATPase, subfamily  V	InterPro Predicted Protein Domain Annotations	1.0	null
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-6215-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NPrEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73924
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74584
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051868
cation transport	GO Biological Process Annotations 2015	1.0	null
GTEX-OHPM-0726-SM-3LK7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29033
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.047269
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06167
inversion	GeneRIF Biological Term Annotations	1.0	null
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52792
COLO-680N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
G6PC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33403
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826743
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6
Agranular insular area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79429
late endosome	GO Cellular Component Annotations 2023	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33914
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845843
TCF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3753
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4853-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU387	DepMap CRISPR Gene Dependency	1.0	2.63428
PRDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32539
Lung adenocarcinoma_LUAD_TCGA-05-4244-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844575
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52224
methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.558
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5106
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13948
WBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21654
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17732_KO_Tmprss2_SRP046010	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.4144
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58088
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98255
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
late endosome membrane	GO Cellular Component Annotations 2025	1.0	null
GTEX-O5YT-0526-SM-32PK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854276
intracellular monoatomic cation homeostasis	GO Biological Process Annotations 2025	1.0	null
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55904
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.33918
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37415
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49852
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14517
TEAD2_02_33	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.80735
RB1_KD_GSE50532_656_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6982-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3356
A-Vietnam-1203_CIP048_RG3-2004(H5N1)_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.42317
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02217
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67871
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02633
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-NR3C1_partners-NR3C1_known_protein_partners_according_to_BioGrid_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	5.59391
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61115
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9216
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221755
HEATR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7416
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88138
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8526
DU4475	DepMap CRISPR Gene Dependency	1.0	2.60464
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53743
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5959
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21555
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
TMEM191B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16763
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848268
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91021
GTEX-R55C-0526-SM-3GIKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989432
18849563-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06488
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05633
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Supplementary_Table_9A_The_effects_of_whole_blood_transcripts_on_COVID-19_severity_with_suggestive_Mendelian_randomization_evidence_P_0_05_using_Genomicc_data_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-KD-A5QS-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12538
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25039
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4165
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-3.07283
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919673
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37417
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84835
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HSPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86257
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43313
GTEX-XGQ4-0826-SM-4AT4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05242
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06481
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.099
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68045
TGFBR3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85664
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70035
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.40342
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31859
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965946
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	1.97372
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040798
Perturb_15138_KO_Nlk_SRP259678	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0884
endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	2.04245
JMSU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7186
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48369
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27574
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9482
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.890493
lateropallial prepiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2888
cellular calcium ion homeostasis	GO Biological Process Annotations 2015	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77615
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43066
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.406
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
Brain Lower Grade Glioma_LGG_TCGA-E1-5307-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GAS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99003
EW-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZBTB49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58739
UACC893	CCLE Cell Line Gene Expression Profiles	1.0	1.69469
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7503
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54017
PMC10709142-41556_2023_1281_MOESM2_ESM.xlsx-Supplementary_Table_1-CLUSTER_1_MAF_upregulated_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Preputial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.444198
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30952
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NS-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9856
Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33424
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
early endosome	GO Cellular Component Annotations 2023	1.0	null
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82869
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4014
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.3962
GHDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8236
SET2	CCLE Cell Line Gene Expression Profiles	1.0	1.47611
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03672
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85655
recycling endosome	GO Cellular Component Annotations 2023	1.0	null
SPIRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38714
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22173
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937858
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE190555,GSE190557_2_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC35E4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24364
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80056
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051204
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941263
TBC1D9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06743
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.988126
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0238
STAT3	ENCODE Transcription Factor Targets	1.0	null
ZNF655	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68124
CHD7	ENCODE Transcription Factor Targets	1.0	null
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03672
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47344
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02541
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58211
Lung adenocarcinoma_LUAD_TCGA-62-8397-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853546
H2BC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48403
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9756
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30043
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.4556
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7364-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.08645
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67141
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55571
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27447
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83409
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27691
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
REEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93881
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26101
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0807
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34184
ABRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22944
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75984
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05633
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.61902
Late endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-11A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07929
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8307
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11472
HCC1419	CCLE Cell Line Gene Expression Profiles	1.0	1.87162
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26187
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89165
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62495
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2599
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73314
Agranular insular area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05685
u	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160017,GSE160022_1_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8206-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60795
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	2.84108
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39948
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07068
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45512
SU-DHL-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OVMANA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36671
rectum	HPA Tissue Protein Expression Profiles	1.0	1.47147
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0853
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44177
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25933
Language disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.811
CHEK1_knockdown_136_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.50584
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42862
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57128
STPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29764
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08407
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10194
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06019
Hailey-Hailey disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
TAF15_02_140	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.32193
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65078
PMC7397849-supp_gad.338681.120_Supplemental_Table_S1.xlsx-S1L_Shared_genes_3way_overlap-Suppl_Table_S1L_Shared_genes_between_YAP1-MAMLD1_YAP1-FAM118B_YAP1-TFE3_in_vitro_human_samples_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56018
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Piriform area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08716
SPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48728
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Hodgkin's lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO Molecular Function Annotations 2015	1.0	null
DCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76784
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-Q2AH-0326-SM-48U1K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881915
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.668
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42271
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71096
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20959
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54F-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56059
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28754
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89792
OVOL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9999
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0594
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00948
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
mantle zone of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01936
CPNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50773
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966881
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1569
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5971
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09461
MDAMB453	DepMap CRISPR Gene Dependency	1.0	4.49638
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05009
Agranular insular area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22148
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53119
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OV-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161295_4_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55584
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29212
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64853
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.92348
calcium ion homeostasis	GO Biological Process Annotations 2025	1.0	null
Perturb_16481_KO_IL6_SRP159090	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.0796
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051204
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07411
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875118
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68257
TPBGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43628
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56614
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1959
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	2.61957
496100287_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2925
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76402
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0239
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TM2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33865
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5399-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04384
chr3_193576473_C_T_b38	GTEx eQTL 2025	1.0	4.37151
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17321
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.40554
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17968
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45851
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28138
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	1.0	1.49208
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68656
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	1.06706
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57733
ITGA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7327
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36463
SRSF7_02_06	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.22239
CFPAC1	DepMap CRISPR Gene Dependency	1.0	3.15834
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07264
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.68463
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35144
METTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84584
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44493
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87404
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09687
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.527841
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68495
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74455
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13303
Childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15991
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.04122
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940788
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1284
NFKBIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29931
recycling endosome	GO Cellular Component Annotations 2025	1.0	null
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38089
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02226
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
Perturb_3521_KD_FACT_SRP328843	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.56457
NBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06686
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41088
MAP1S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64147
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15187
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4651
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33252
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8190596-mmc2.xlsx-ETV6_mut-ETV6_mut_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_183_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.4103
Apraxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84902
SETD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10483
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41812
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24868
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06628
ZNF705B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89438
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15187
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03966
PLEKHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44113
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04856
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53959
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3959
ALEXANDERCELLS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98788
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05632
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62538
Edema	CTD Gene-Disease Associations	1.0	1.2772
Fra-1_KO_GDS5078_402_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.15257
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38229
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51244
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31703
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04369
STAT3	ChEA Transcription Factor Targets	1.0	null
apraxia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00963
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32227
DNLZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94159
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47725
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
recycling endosome membrane	GO Cellular Component Annotations 2025	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11443
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CEBPG_CEBPG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35611
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45086
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6474
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25711
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19875
NCIH209	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92303
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49616
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29298
TET2_KO_GDS4287_429_mouse_LSK - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3320-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840793
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
NKX3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58826
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.04465
Teeth hard tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37165
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02571
membrane region	GO Cellular Component Annotations 2015	1.0	null
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0737
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94671
PMC5967331-41467_2018_4384_MOESM4_ESM.xlsx-Sup_data1_with_CCF_txt-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97019
EZH2	ENCODE Transcription Factor Targets	1.0	null
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94512
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RC-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11740_KO_Trp53_SRP221563	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.87531
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41996
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0934
GSE211177,GSE211178_9_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2749
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04343
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44765
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ptype	GeneRIF Biological Term Annotations	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05
superficial stratum of InsCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.439
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59092
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17345
Lassa Fever Virus_4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.31803
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959118
Speech disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.83
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.870343
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09733
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962445
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.28135
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33191
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.748
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054109
hsa-miR-4323	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38749
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05541
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62608
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8827
GTEX-X4EP-0826-SM-3P5YK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964564
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM47E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44114
Perturb_12079_KO_Ezh2_SRP060232	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.4362
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54086
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.37195
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849166
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4330-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.54958
DRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22621
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.859838
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03461
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34652
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82818
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43285
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91359
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18849563-SuppTable3a	GeneSigDB Published Gene Signatures	1.0	null
CCDC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95608
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5585
QSOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39351
LU65	CCLE Cell Line Gene CNV Profiles	1.0	1.78999
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895867
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02703
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-16	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30859
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12228
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18954
Perturb_17487_KO_Elavl1_SRP153419	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.73311
hsa-miR-4786-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02907
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11971
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94023
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965946
localization	GO Biological Process Annotations 2015	1.0	null
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	1.78504
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.44954
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897381
SMYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29173
GSE78199_2_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90326
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14975
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2818
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OAW28	CCLE Cell Line Gene CNV Profiles	1.0	1.37508
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.43705
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34448
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058875
RHJT	DepMap CRISPR Gene Dependency	1.0	4.94496
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0654
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3248
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XY-0326-SM-46MVZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
PUM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73456
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
X-linked distal spinal muscular atrophy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29243
preweaning lethality, incomplete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
IDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55992
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883636
individual	GeneRIF Biological Term Annotations	1.0	null
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
layer 5 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02699
FOXA1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.06625
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6501
HEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58795
GABPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17793
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16399
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927032
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
not applicable_asthma_GSE43696_369_mouse_bronchial epithelial cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
JHH2	DepMap CRISPR Gene Dependency	1.0	2.79818
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76864
Lung squamous cell carcinoma_LUSC_TCGA-43-2581-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64853
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14671
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32958
CAV3_KO_GDS3533_17_mouse_mammary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.148857
Dyslexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.245
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47971
ALKAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84992
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872003
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883636
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63037
Perturb_13810_KD_Nipbl_ERP013418	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
HAD-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
RPP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0446
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97062
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal retina outer nuclear layer morphology	IMPC Knockout Mouse Phenotypes	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9041
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0244
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9754
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00113
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18791
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38134
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0187
P-type ATPase, phosphorylation site	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-204	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22274
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4781-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Adenoma_Adrenal gland_GSE8514	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.55686
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Landau-Kleffner syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39945
ROGDI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28944
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15609
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6736
nasopharynx	HPA Tissue Protein Expression Profiles	-1.0	-0.985541
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07139
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.774
PLXNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41489
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.88
CHST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81996
PE/CA-PJ15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0699
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87322
cellular ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Benign epilepsy with centrotemporal spikes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.78
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
esophagus	HPA Tissue Protein Expression Profiles	-1.0	-0.985541
Perturb_16561_KO_Atrx_SRP308209	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.806
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68605
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50254
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5901-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR7530	CCLE Cell Line Gene Expression Profiles	1.0	1.40868
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_H_sapiens_970_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81937
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76977
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77524
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.994278
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02725
TIMM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35715
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49279
PMC10794847-mmc6.xlsx-PIAS1_KD_down-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.747
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920629
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.850104
RCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73592
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0863
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2535
SEC61G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31311
CTDSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88443
Brain Lower Grade Glioma_LGG_TCGA-HT-7485-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35934
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907707
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.34067
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFKB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03179
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854786
GSE119701_0_v_1_phf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
late endosome	GO Cellular Component Annotations 2025	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2573
Necrosis	CTD Gene-Disease Associations	1.0	1.94469
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A8JM-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
CMLT1	DepMap CRISPR Gene Dependency	1.0	6.93259
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.88472
TMEM219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64757
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.01361
PAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96702
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0013
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.965738
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.62304
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18622
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66117
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855689
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38548
HT115	CCLE Cell Line Gene Expression Profiles	-1.0	-2.72236
ZNF346	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43437
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.55437
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11641
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88849
SK-HEP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
preweaning lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.949305
TRIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94358
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901994
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.04684
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04956
PMC10823279-CAS-115-283-s001.xlsx-Table_S6-Table_S6_List_of_182_genes_particularly_down-regulated_by_AR_in_AILNCaP14_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GOLGA8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80561
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48172
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.977813
GTEX-T5JW-1426-SM-4DM5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29354
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.829112
GSE172020_1_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Monoclonal gammopathy of undetermined significance (MGUS)_Bone Marrow_GSE5900	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.38789
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00145
Perturb_4485_OE_Mir29a/Mir29b1_SRP220351	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.10558
Recycling endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GOLPH3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUW-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97953
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
testis	HPA Tissue Protein Expression Profiles	1.0	0.840644
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81719
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68622
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25765
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866172
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03336
LC1F	CCLE Cell Line Gene CNV Profiles	1.0	1.44081
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53618
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01319
membrane	GO Cellular Component Annotations 2015	1.0	null
CLPTM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23682
Water	HMDB Metabolites of Enzymes	1.0	null
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.30688
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2019
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45422
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
496100288_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17499
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04095
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17738
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15148
fenofibrate_homo sapiens_gpl4044_gse15483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941378
Lassa Fever Virus_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.66645
chr3_193579146_A_T_b38	GTEx eQTL 2025	1.0	1.08974
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68354
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3632
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8257
Inflammation	CTD Gene-Disease Associations	1.0	1.8128
lower dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05249
HDGF_02_104	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.20945
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59434
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3447
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Dystonia 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47038
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38419
Hereditary spastic paraplegia 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.068
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91596
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4913
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Calyx of Held	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3108
PMC8944338__F4	PFOCR Pathway Figure Associations 2024	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4309
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08448
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	2.14628
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992862
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRC-RCZ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991755
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.60326
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912533
CCDC71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76428
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86826
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31515
MCIDAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48644
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61844
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1647
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54736
LZTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9566
PANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36006
ERVMER34-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96823
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35101
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21593
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19828
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.913043
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-889	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77754
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41233
LN235	DepMap CRISPR Gene Dependency	1.0	4.32607
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular calcium ion homeostasis	GO Biological Process Annotations 2023	1.0	null
EW-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1992
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01747
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2372
MEF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07482
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3872
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10727
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
Cef cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
CAL29	DepMap CRISPR Gene Dependency	1.0	3.02142
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.89461
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91977
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	1.43639
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CCT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16193
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13932
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.881508
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86292
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205550,GSE205552_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.1927
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH2452	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52879
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.978
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
ELK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42702
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858241
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41509
GTEX-X62O-0826-SM-46MW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894522
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7841
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29149
TCF4	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6212-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.549312
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07068
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE198165,GSE198166_5_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883911
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45956
PRPF4_02_128	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
BFTC-905	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
GSE213650_0_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0987
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068478
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55971
NECTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15783
TCP11L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63562
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16578
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01034
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18543
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.792897
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867471
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.38737
calcium ion homeostasis	GO Biological Process Annotations 2015	1.0	null
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47516
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02017
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03979
KARPAS-620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10951
LASV_FML29_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.1784
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13377
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73839
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24217
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.61248
GSE73628_8_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875905
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059027
OE33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
MBLAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25905
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46642
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17312
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_12050_KD_Mtss1_SRP185976	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Agranular insular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73773
Excretory canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4494
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.971351
MITF	ChEA Transcription Factor Targets	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73465
NKX6-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48725
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42326
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36542
Endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE166315_2_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.089821
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0673
hydrolase activity, acting on acid anhydrides	GO Molecular Function Annotations 2015	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.97777
LN319	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95501
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06327
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27741
RBM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
ZFP69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89684
ion homeostasis	GO Biological Process Annotations 2015	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040842
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90182
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3406
Perturb_5511_KO_Vdr/Med1_SRP282245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.6351
YMB1	CCLE Cell Line Gene Expression Profiles	1.0	1.37467
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A5XV-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884711
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891219
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67102
SW1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966881
TATDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1014
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4329-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53942
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0817
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7686
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40881
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44808
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46473
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6832
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834852
hsa-miR-103a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.8916
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.61631
LC-1-SQ	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29299
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73724
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
HRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37959
HNF1B	JASPAR Predicted Transcription Factor Targets	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0454
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.14273
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966881
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14431
JHU-022	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45556
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.870067
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24591
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.830689
GSE190534,GSE190536_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5443
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883636
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48315
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE30	DepMap CRISPR Gene Dependency	1.0	2.16168
thiamine-responsive megaloblastic anemia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12184
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31306
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08051
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58461
RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27447
electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.749237
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9681
PMC10928104-41419_2024_6576_MOESM4_ESM.xlsx-S14-E2F1_2_3_targets_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular monoatomic cation homeostasis	GO Biological Process Annotations 2023	1.0	null
PMC5771393-ACEL-17-na-s003.xlsx-FOXO1_Correlation_Pos-HUGO_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66246
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15814
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969478
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05249
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87348
GTEx Ovary 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	5.83722
GTEX-XUJ4-1126-SM-4BOPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830698
nod2_21335489_hek293_lof_human_gpl570_gds4416	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.170793
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57171
HOOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78071
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67655
P-type ATPase	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09654
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50127
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12843
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CCNDBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42455
Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
Reading disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.30576
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.188
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865334
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25816
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03219
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00981
GSE210476_9_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843792
HCC1599	CCLE Cell Line Gene Expression Profiles	1.0	1.64137
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950746
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827128
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7887-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
SNU1033	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51532
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4256
SLC25A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03983
ZSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92109
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05488
MRPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81742
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5018
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982155
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4332-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Astrocyte_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.863981
MAPK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61914
496100331_TCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40445
NIFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12525
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50248
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00905
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6004
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28415
NAT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87141
SUM52PE	DepMap CRISPR Gene Dependency	1.0	3.35797
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92595
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62527
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2192
H4C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16485
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18907
neoplasm of the pancreas	GWASdb SNP-Phenotype Associations	1.0	0.536325
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10403
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42247
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09738
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44164
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860507
PTGER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74099
Brain Lower Grade Glioma_LGG_TCGA-HT-7873-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT5B-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	3.29039
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961959
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27323
NYNRIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31919
ZNF222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36253
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.265757
GSE120336_1_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63914
prostate_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
Hypertrophy	CTD Gene-Disease Associations	1.0	1.32547
Perturb_4418_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.38501
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.096644
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MH-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916871
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25902
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99612
ion transport	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4753-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55736
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884449
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07019
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19181
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217346
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80532
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
18559498-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-4420	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
chr3_193671624_C_A_b38	GTEx eQTL 2025	1.0	2.23224
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6322
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0558
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8022
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07821
Gizzard	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
Perturb_109_KD_FOXC1_SRP276213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
IPO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22091
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40803
Lung adenocarcinoma_LUAD_TCGA-55-7903-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65982
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88773
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19065
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3973
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864553
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0697
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46882
hsa-miR-548k	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PRDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04936
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17772
t99-vena-cava_male_8w	MoTrPAC Rat Endurance Exercise Training	-1.0	-9.45494
SYNCRIP_KD_GDS3578_86_human_MM1S	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
DQX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37902
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.954505
T47D	CCLE Cell Line Gene CNV Profiles	1.0	1.72864
BIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42502
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06858
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28658
NAGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80091
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intellectual disability-severe speech delay-mild dysmorphism syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
atp binding	GO Molecular Function Annotations 2015	1.0	null
mantle zone of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.439
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897237
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.04093
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48386
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896033
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84806
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.942232
Hereditary spastic paraplegia 78	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.722
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62185
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19147
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04228
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18051
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925531
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30226
hsa-miR-4645-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49506
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79749
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895867
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8630-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25661
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02146
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14585
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983076
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21655
tfap2c_18353300_e16dot5_skin_lof_mouse_gpl1261_gds3171	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.548842
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.92878
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XD-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04372
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21437
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
atpase	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14712
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.985541
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78293
FEZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14924
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.92927
GIGYF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09578
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.192344
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	2.4541
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0838
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55577
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01916
NCIH69	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82403
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4521
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31113
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29139
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1521
LDB1_02_35	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.5025
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48596
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42243
FAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06389
Dental caries	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33186
anion binding	GO Molecular Function Annotations 2015	1.0	null
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81045
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
STYXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93348
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26629
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07982
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87155
u266	HPA Cell Line Gene Expression Profiles	1.0	0.98715
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10928104-41419_2024_6576_MOESM4_ESM.xlsx-S14-MYBL2_targets_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74179
Brain Lower Grade Glioma_LGG_TCGA-RY-A845-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12311841-CTM2-15-e70424-s001.pdf-16-EMX2-like_EMX2	Rummagene Transcription Factor Associations 2026	1.0	null
BECKER	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
NCI-H1694	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GNG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03775
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80607
TFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64463
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09171
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15752
HOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68515
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23907
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8087-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.32132
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46658
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GGCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84393
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
MRPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09951
MDAMB415	CCLE Cell Line Gene Expression Profiles	1.0	1.89751
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32529
CHAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84205
NACAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85549
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73135
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07035
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21841
JK1	CCLE Cell Line Gene Expression Profiles	1.0	1.9571
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	3.80905
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23392
ion binding	GO Molecular Function Annotations 2015	1.0	null
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
coding	GeneRIF Biological Term Annotations	1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.62159
EML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57782
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10605
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70549
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83416
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
GSE99187_1_v_0_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96814
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.077629
GSE182680,GSE182683_5_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93311
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68383
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07139
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37841
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05927
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.952372
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.985541
AFDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47013
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63996
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18907
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2228	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56447
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TZ-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8981
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854482
HSF1_02_73	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.1964
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6085
UMNSAH/DF-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
VDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9268
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841658
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984312
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_14715_KO_Tbx3_SRP305624	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.88968
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882102
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	1.0	1.7999
CD79B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90974
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990726
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40173
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10687
GTEX-OIZI-1326-SM-3NB1B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99781
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44956
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894941
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70553
GTF2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04458
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.906743
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7738
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22479
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
Perturb_7785_KD_MTREX_SRP043962	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.32169
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12108
MYRFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0212
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853161
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958303
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70121
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71079
hsa-miR-499a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840766
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PARP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21377
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.256652
Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
8305C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09258
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.40311
FOXP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27859
ARID3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95479
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47575
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63578
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6792-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7566
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48113
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08537
Ventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KCIMOH1	DepMap CRISPR Gene Dependency	1.0	4.28483
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02665
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6376
NB7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942639
SIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40425
speech-language disorder-1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.395
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
Perturb_4179_KO_Tsc1_SRP279018	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.2631
ADPGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0636
Perturb_16302_KO_Esr1_SRP115139	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.22163
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69897
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18954
PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64509
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00945
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2525
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02544
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93659
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIN7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22085
Tongue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.917199
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3301
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.69991
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32755
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-5155-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28774
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98222
SLC25A44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10241
Gut granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3278
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14671
ADP	HMDB Metabolites of Enzymes	1.0	null
TOV21G	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96127
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95753
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56533
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29212
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92487
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.870105
MKRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15339
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45378
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860959
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30653
PDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74069
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12131
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75192
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SU-DHL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49156
Infralimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41147
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.71899
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40822
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051643
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840723
SP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27988
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78421
H-EMC-SS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26668
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058839
single-organism localization	GO Biological Process Annotations 2015	1.0	null
CNST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98051
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02146
Lung adenocarcinoma_LUAD_TCGA-50-5944-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935346
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7768
DB	DepMap CRISPR Gene Dependency	1.0	4.12294
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
NCIH1339	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20376
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40607
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02265
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
LU-65	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX5	ChEA Transcription Factor Targets	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040707
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918301
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.967659
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54654
IGFBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39662
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Middle temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
A253	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55622
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94048
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835471
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27558
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42462
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09041
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23724
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89516
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95057
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.02247
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17038
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08429
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25479
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93463
Hyperplasia	CTD Gene-Disease Associations	1.0	1.31746
SNCA_KO_GDS4153_442_mouse_Cerebellum - 6 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12491
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53001
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965946
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MON1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45485
pdx1_22135308_duodenum_lof_mouse_gpl1261_gds4348	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.464976
GTEX-SNOS-0426-SM-32PMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20052
SAP30	ENCODE Transcription Factor Targets	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5666
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21594
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99555
early endosome membrane	GO Cellular Component Annotations 2025	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28997
Proprotein convertase 1/3 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
MFE-280	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14671
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03231
20421987-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38695
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1537
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28048
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01133
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59539
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHO-MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.762
molecular_function	GO Molecular Function Annotations 2015	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860857
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96701
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86855
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33516
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74819
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2975
hsa-miR-211	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
KNS-62	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23399
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0509
SEPTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51326
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50634
chr3_193509756_A_G_b38	GTEx eQTL 2025	1.0	2.10976
communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.409787
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LO68	DepMap CRISPR Gene Dependency	1.0	2.52587
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EXOC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51413
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99921
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869818
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.927127
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.852108
Bipolar Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56666
SERPINB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92333
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
DYNLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11351
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.986099
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7173
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
speech disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.36422
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.924781
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74023
LTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77362
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GU-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOS	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01796
DACT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15857
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21633
extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.413382
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01298
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6179
DSCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68241
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44143
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02351
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965946
HEC151	CCLE Cell Line Gene CNV Profiles	1.0	1.64812
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4795-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCLRE1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81953
AML193	DepMap CRISPR Gene Dependency	1.0	2.00095
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.985541
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1378
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.38448
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A627-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71315
GXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4317
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3429
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	2.0818
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36671
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15789
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RM2N-0626-SM-48FD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920619
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94744
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992716
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00628
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.950526
sleep disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.947435
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1805
TMX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4983
late endosome membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834241
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00651
FBXO27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90672
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67776
TMEM123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27917
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14505
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4741-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.82057
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826186
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85049
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49322
RI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69882
TMEM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31728
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988216
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07527
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43167
GTEX-WEY5-0526-SM-3GIKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966789
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02858
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.961608
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12381
INTS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73296
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05655
LMSU	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22463
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64355
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98339
agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00246
CDCA7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53106
MICU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81631
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
NB6	DepMap CRISPR Gene Dependency	1.0	6.99074
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3785
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08832
RBBP5	ENCODE Transcription Factor Targets	1.0	null
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24747
GTEX-OHPL-0526-SM-3NM8U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827299
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68082
Late endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
binding	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4177-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60663
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14175
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984312
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20109
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71035
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6135-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96601
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.73452
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4281	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03256
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.03009
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3194
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null