association dataset threshold value standardized value
BRSK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90723
behavior/neurological phenotype MPO Gene-Phenotype Associations 1.0 null
H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
regulation of systemic arterial blood pressure by hormone GO Biological Process Annotations 2023 1.0 null
autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.761454
H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
amide binding GO Molecular Function Annotations 2015 1.0 null
Cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.159
Olfactory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.841
stomach HPA Tissue Gene Expression Profiles 1.0 1.33688
nipple TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.291008
FBXO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98298
v1br GeneRIF Biological Term Annotations 1.0 null
CERS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93716
Median nucleus of thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.522
GSE48812_3_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null
Medial septum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.284
TACC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42344
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
D-283MED GDSC Cell Line Gene Expression Profiles -1.0 -1.82538
G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09728
H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
PSAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25865
CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.9993
SHISAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63327
GSE240386,GSE242143_1_v_3_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null
CRCGN015_MCF10A.TP53.M_24H:F17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.8357
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366 Rummagene Transcription Factor Associations 2026 1.0 null
Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
TCL1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6009
AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null
Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.146
variation GeneRIF Biological Term Annotations 1.0 null
CRCGN015_MCF10A.TP53.M_24H:M07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.152
regulation of biological quality GO Biological Process Annotations 2015 1.0 null
Raynaud disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.116
Dopaminergic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.057
Calcitonin family receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.795
HDAC2 ENCODE Transcription Factor Targets 1.0 null
Lung adenocarcinoma_LUAD_TCGA-86-A4P7-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Adrenal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.885
intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
Tripartite attachment complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.526
[3H]AVP (HUMAN, MOUSE, RAT) DGIdb Drug Targets 2026 1.0 0.315071
ZR751 CCLE Cell Line Gene CNV Profiles 1.0 2.07978
H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GATA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54697
integral component of plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
patientcontrol GeneRIF Biological Term Annotations 1.0 null
GSE202603_1_v_2_bhlhe40_mouse RummaGEO Gene Perturbation Signatures -1.0 null
CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
JEG-3 GDSC Cell Line Gene Expression Profiles -1.0 -1.47499
[3H]D[CHA4]AVP DGIdb Drug Targets 2026 1.0 1.26029
Hemorrhage CTD Gene-Disease Associations 1.0 1.22664
trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055443
abnormal seizure response to inducing agent MPO Gene-Phenotype Associations 1.0 null
DDX60L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02813
H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
endocrine process GO Biological Process Annotations 2015 1.0 null
response to peptide GO Biological Process Annotations 2015 1.0 null
FCGR2B MSigDB Cancer Gene Co-expression Modules 1.0 null
plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.19733
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4987-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
D[D-PHE2]AVP DGIdb Drug Targets 2026 1.0 0.420095
PMC4390530-NIHMS667786-supplement-1.xlsx-Sheet1-Supplementary_Table_2_Genes_closest_to_AR_induced_ASH2L_peaks_AR Rummagene Transcription Factor Associations 2026 1.0 null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Venom gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.543
CLDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99861
NCI-H322M COSMIC Cell Line Gene Mutation Profiles 1.0 null
HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.878565
SNU407 CCLE Cell Line Gene CNV Profiles 1.0 1.59915
GRIN3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8276
H3K27me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
KLF13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10532
BRD-K87602457 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.19289
head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
vasopressin receptor activity GO Molecular Function Annotations 2025 1.0 null
Dorsal striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.918
EWSR1_KD_GDS4962_465_human_Ewing sarcoma and prostate cancer GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
Nelson syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.367
mammary gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.074467
BRD-K69840402 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36272
CLDN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25381
YAPC CCLE Cell Line Gene CNV Profiles -1.0 -1.42918
CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Psychiatric Status Rating Scales HuGE Navigator Gene-Phenotype Associations 1.0 null
CRCGN008_HEPG2_24H:C05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.01525
plasma membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
BRD-K88385836 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.93391
embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.0074
CRCGN016_MCF10A.WT.HP_24H:K20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.8263
H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
CTCF_GM12867_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null
CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null
diabetes insipidus DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.398962
ZNF816 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.9877
GSE152734,GSE152735_2_v_0_pbrm1_human RummaGEO Gene Perturbation Signatures 1.0 null
DUXB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93697
BRD-K86966177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32609
IRAK2_knockout_39_GSE10765 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.35497
BRD-K15654812 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19814
NIHOVCAR3 CCLE Cell Line Gene CNV Profiles 1.0 1.94777
BRD-K97934318 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21244
H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
regulation of catalytic activity GO Biological Process Annotations 2015 1.0 null
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
BRD-K85546819 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.75416
SFXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85499
BRD-K93927229 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09673
EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
HEXB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.3704
ATP13A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72391
H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
ChIP_H3K27me3_17603471_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null
Cystic kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.388
H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00305
Adrenocortical cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.654
urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.330827
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
multicellular organismal process GO Biological Process Annotations 2015 1.0 null
ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5314
H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.03388
Collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.027
Perturb_14301_KD_HNRNPM_SRP230637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.03587
whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01549
Pituitary gland tumor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.65
Nucleus accumbens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.929
KLK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77323
Kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.637
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7842-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
CRCGN016_MCF10A.TP53.M_24H:H08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.7343
K562 BioGPS Cell Line Gene Expression Profiles -1.0 -1.59703
RBBP5 ENCODE Transcription Factor Targets 1.0 null
abnormal seizure response to pharmacological agent MPO Gene-Phenotype Associations 1.0 null
Perturb_14306_KD_SRSF1_SRP230637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0
d[Leu4]LVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
PIGW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83176
POGLUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80027
disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.285086
H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
MM1S DepMap CRISPR Gene Dependency 1.0 4.02702
H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null
nelivaptan Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5584
CNOT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88225
hindbrain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CRCGN015_MCF10A.WT.HP_24H:P22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.14165
PAX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9253
BRD-K85559506 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16222
decreased circulating glucocorticoid level MPO Gene-Phenotype Associations 1.0 null
H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
ARGIPRESSIN DGIdb Drug Targets 2026 1.0 0.286429
H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null
GPRIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47033
positive regulation of cellular biosynthetic process GO Biological Process Annotations 2023 1.0 null
CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
D(CH2)5[D-ILE2,ILE4,ALA-NH29]AVP DGIdb Drug Targets 2026 1.0 0.420095
ZR7530 CCLE Cell Line Gene CNV Profiles 1.0 1.44621
BRD-K17339982 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12139
ATOSIBAN DGIdb Drug Targets 2026 1.0 0.630143
MAZ ENCODE Transcription Factor Targets 1.0 null
ATM_DN.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null
GOLGA6L9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26668
BRD-K47658117 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05204
cell type benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044149
hsa-miR-4732-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397
MRK-NU-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899
UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.45379
CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CRACR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02303
decreased aggression MPO Gene-Phenotype Associations 1.0 null
course GeneRIF Biological Term Annotations 1.0 null
H3K4me1_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Substance-Related Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null
RYBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83938
H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
OGFOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53959
GSE145915_5_v_1_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null
intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.254017
ELK1::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6942
H3K4me1_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
hesperetin-1947 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
genotypes GeneRIF Biological Term Annotations 1.0 null
SPEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80881
BRD-K10911459 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07161
BRD-K11008696 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08496
Traumatic brain injury DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012
YWHAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78938
Seizures CTD Gene-Disease Associations 1.0 1.02485
CGRP receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.986
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
cerebellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.46775
EBC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.35293
SLC25A28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36692
ZNF559 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51874
citiolone-4311 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
supports GeneRIF Biological Term Annotations 1.0 null
adrenal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.35132
MRPL32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37707
C4orf46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6521
ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.4442
Entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.36
cell periphery COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.180339
H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
protein kinase binding GO Molecular Function Annotations 2015 1.0 null
GSE228181_3_v_1_idh1_mouse RummaGEO Gene Perturbation Signatures 1.0 null
cellular response to hormone stimulus GO Biological Process Annotations 2025 1.0 null
PIGF_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null
H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
NH12 DepMap CRISPR Gene Dependency 1.0 2.94894
BRD-K08489825 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29581
CDC42BPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81017
SCMCRM2 DepMap CRISPR Gene Dependency 1.0 2.57443
BRD-K00793226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10099
DGKQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57589
YBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67625
TACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29384
mental depression DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.697109
CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Lung adenocarcinoma_LUAD_TCGA-86-A4JF-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K87180723 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06363
phospholipase C-activating G protein-coupled receptor signaling pathway GO Biological Process Annotations 2025 1.0 null
HLA-DRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62541
Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
nicergoline-5775 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-GK-A6C7-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Auditory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.953
adrenal cortex disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.103
Bipolar disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.915
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Organ system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.38
Interneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.575
Retrosplenial region TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.656
BRD-K86158100 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.156
BHLHA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53005
CLIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59221
H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.08166
GSE80098,GSE80366_0_v_6_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null
M/G1 phase-specific MADS box-forkhead transcription factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.6
496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.33078
MPST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16066
THAP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87073
cellular_component LOCATE Curated Protein Localization Annotations 1.0 null
GSE171352_2_v_3_glucagon_human RummaGEO Drug Perturbation Signatures -1.0 null
Olfactory tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.274
neostriatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.21673
CRCGN009_HEPG2_24H:E13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.94053
TM7SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76846
EN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81174
HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20988
MEST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44312
BCAP31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89928
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null
IPO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82304
BAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66013
POLR3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7805
SLR25 CCLE Cell Line Gene Expression Profiles 1.0 1.84695
CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
PLEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29124
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CRCGN011_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.7449
ARFGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10512
H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K95666495 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31434
Perturb_13656_KO_TERT_SRP291201 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.00598
PRRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.246
Olfactory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.833
SP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41998
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null
C1orf216 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04149
Supraoptic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.493
CAMLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83653
endocrine/exocrine gland phenotype MPO Gene-Phenotype Associations 1.0 null
plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null
PLAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96181
positive regulation of multicellular organismal process GO Biological Process Annotations 2025 1.0 null
PU.1-20176806-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
RAF1_overexpression_220_GSE42964 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.7346
regulation of vasoconstriction GO Biological Process Annotations 2015 1.0 null
VASOPRESSIN TANNATE DGIdb Drug Targets 2026 1.0 0.420095
BRD-K96779993 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.99422
Venom apparatus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.524
NQO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87222
GSE166767_1_v_2_ctcfl_human RummaGEO Gene Perturbation Signatures 1.0 null
hsa-miR-2682 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003
SC-58125-542 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
G protein-coupled receptor homodimeric complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.287
Panic Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null
CDCA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39502
TRPC4AP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13403
BRD-K75177817 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.65769
CTCF_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
positive regulation of MAPK cascade GO Biological Process Annotations 2025 1.0 null
RCOR1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
LAMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12232
PAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1057
ARID3A ENCODE Transcription Factor Targets 1.0 null
H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
TMED7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98354
GSE144231_2_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null
REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
extracellular matrix part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.052816
ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.793
BRD-A77907596 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54228
NALF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66503
CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Acth Syndrome, Ectopic DisGeNET Gene-Disease Associations 1.0 null
11906190-Table2a-1 GeneSigDB Published Gene Signatures 1.0 null
H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
TC32 CCLE Cell Line Gene Expression Profiles 1.0 1.38471
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
GPCRs, Class A Rhodopsin-like(Homo sapiens) WikiPathways Pathways 2014 1.0 null
CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3 Rummagene Transcription Factor Associations 2026 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04057
H3K4me1_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
GSE233647_2_v_3_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null
nucleotide-excision repair factor 2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.033
MIEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89397
CUL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23198
CPEB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67631
GABPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17793
Alcoholic Intoxication, Chronic DisGeNET Gene-Disease Associations 1.0 null
H-EMC-SS GDSC Cell Line Gene Expression Profiles -1.0 -1.72409
STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null
ZFAND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37382
muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053107
[PHAA1,D-TYR(ET)2,VAL4,LYS6,TYR-NH28,DES-GLY9]AVP DGIdb Drug Targets 2026 1.0 0.420095
hyperactivity GeneRIF Biological Term Annotations 1.0 null
Cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.19
H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
cellular process GO Biological Process Annotations 2015 1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4644-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
PRKCA Pathway Commons Protein-Protein Interactions 1.0 null
MBLAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18039
BRD-K40425733 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.61603
PARPBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.50772
SLC35F5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29728
HS729 CCLE Cell Line Gene CNV Profiles -1.0 -1.82346
PMC3500769-srep00875-s3.xls-CEBP-Time_4_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null
H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null
LRFN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24042
STOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60371
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA Rummagene Transcription Factor Associations 2026 1.0 null
SHSY5Y CCLE Cell Line Gene Expression Profiles -1.0 -1.98346
HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null
COX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25957
skeletal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055595
CTCF_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K31250130 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13962
HNRNPA0 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79512
brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.408
CTCF_MEL cell line_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Pancreas-pancreatic delta cell Tabula Sapiens Gene-Cell Associations 1.0 2.32331
BRD-K02420839 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39085
intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.238119
ENTPD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46569
SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
POLR2A ENCODE Transcription Factor Targets 1.0 null
CRCGN014_HEPG2_24H:E01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.12199
thi GeneRIF Biological Term Annotations 1.0 null
ESRRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.41459
REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.519961
BRD-K03353688 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.66669
Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.286
PMC10725467-41467_2023_44159_MOESM4_ESM.xlsx-Supplementary_Data_10-Supplementary_Data_10_Nonsynonymous_mutations_in_TFE3-RCC_TFE3 Rummagene Transcription Factor Associations 2026 1.0 null
SRF_KO_GDS3732_148_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
Type 2 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.35
Lateral vestibular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788
NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01037
CTCF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.558457
CRCGN013_HEPG2_24H:I14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.31682
ETV4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9685
GSE168807_0_v_7_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null
ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
KMS21BM CCLE Cell Line Gene CNV Profiles 1.0 1.48655
abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.041173
Cortical collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.519
PSME3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49898
ZNF208 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6389
THRAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00074
Acidosis CTD Gene-Disease Associations 1.0 1.12288
Bipolar Disorder_Lymphocyte_GSE7036 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 0.975925
KLHDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66589
H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.27
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K81779733 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01597
DHX40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0255
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL1-CLOSEST_GENE_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null
SNU324 CCLE Cell Line Gene CNV Profiles 1.0 1.37247
SUPHD1 CCLE Cell Line Gene CNV Profiles 1.0 2.78944
cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.351923
HEC6 CCLE Cell Line Gene Expression Profiles -1.0 -1.71287
EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881966
TMEM160 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66574
CRCGN014_HEPG2_24H:H02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.13318
H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Nucleus preopticus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.475
synaptic cleft COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.341907
TGFB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39417
BRD-K47471281 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.88535
BRD-K04786080 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40311
HCC-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null
Temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.19
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
H1-5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68552
RCOR1 ENCODE Transcription Factor Targets 1.0 null
LXR-22292898-THP-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
DEDD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66932
Perturb_2986_KO_BAP1_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0
cellular divalent inorganic cation homeostasis GO Biological Process Annotations 2015 1.0 null
BCAN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04989
ZCCHC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00722
CLOCK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95777
RPSA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76554
DUSP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79176
H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
childhood-onset mood disorders GAD Gene-Disease Associations 1.0 null
Nrf2_deficiency_GDS3406_156_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
Obesity DisGeNET Gene-Disease Associations 1.0 null
NPLC/PRF/5 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.955
sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061969
Major Depressive Disorder DisGeNET Gene-Disease Associations 1.0 null
H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H2AFZ ENCODE Transcription Factor Targets 1.0 null
Gastrointestinal endocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.951
D(CH2)5[TYR(ME)2,THR4,PHE(3I,4N3)-NH29]OVT DGIdb Drug Targets 2026 1.0 0.315071
H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
NCIH526 CCLE Cell Line Gene CNV Profiles -1.0 -1.55728
CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53967
CAL-12T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01244
alclometasone-6229 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
D[LEU4]AVP DGIdb Drug Targets 2026 1.0 0.315071
SW1463 GDSC Cell Line Gene Expression Profiles 1.0 1.60562
BRD-K32251128 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06931
BRD-K60337438 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68324
Olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.678
SIX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48475
H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null
LU-65 COSMIC Cell Line Gene Mutation Profiles 1.0 null
regulation of systemic arterial blood pressure by vasopressin GO Biological Process Annotations 2025 1.0 null
MERO83 DepMap CRISPR Gene Dependency 1.0 3.89958
APUD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.954
dizocilpine-2232 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
elevated GeneRIF Biological Term Annotations 1.0 null
blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.443731
DNAJC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13568
[3H]OT (human mouse rat) Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.946081
small adrenal glands MPO Gene-Phenotype Associations 1.0 null
Von Willebrand's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.401
Bulimia nervosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04
SRSF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5768
Dorsal raphe nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.322
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5186-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K10505056 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.56021
Desmopressin HMDB Metabolites of Enzymes 1.0 null
BRD-K84846130 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0255
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
vasopressin GeneRIF Biological Term Annotations 1.0 null
SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26018
Agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.568
oltipraz LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00606
PH-284 DrugBank Drug Targets 1.0 null
SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
TNNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13726
HMGN3 ENCODE Transcription Factor Targets 1.0 null
cellular homeostasis GO Biological Process Annotations 2015 1.0 null
d[Leu4]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
FBXL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.75335
Endocrine organ benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.629
PPP1R13L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44994
CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57639
CSNK1A1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80478
activation of phospholipase C activity GO Biological Process Annotations 2023 1.0 null
H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
BRD-K95822658 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.62262
abnormal circulating testosterone level MPO Gene-Phenotype Associations 1.0 null
psych GAD High Level Gene-Disease Associations 1.0 0.303208
JJ012 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12523
Creb5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.2822
CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Cmah_KO_GDS4770_421_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
Axon terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.511
GSE74490_0_v_1_triptolide_mouse RummaGEO Drug Perturbation Signatures 1.0 null
HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921932
Myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.069
chemdependency GAD High Level Gene-Disease Associations 1.0 0.293278
HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57755
Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.124
metolazone-1932 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
genotype GeneRIF Biological Term Annotations 1.0 null
HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42372
WHSC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GSE48812_4_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null
ADAMTS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17553
CRCGN014_HEPG2_24H:A03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5947
Cell type benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.44
BRD-K83297764 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4399
TMEM258 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29118
ZNF565 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59642
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5907-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
GSE145915_3_v_2_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null
intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
MAP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70969
intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
D(CH2)5[D-ILE2,ILE4,ALA-NH2]AVP DGIdb Drug Targets 2026 1.0 0.420095
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
Neurosecretory vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.75
H3K4me1_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
pancreas HPA Tissue Gene Expression Profiles 1.0 0.882085
LEPROT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51776
ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3573
H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Obesity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.306
H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
MC1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19267
C11orf54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53885
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9058
SLC25A17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12559
SLC35D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22101
SLC35F6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10008
GSE235066_4_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null
GRM CCLE Cell Line Gene Expression Profiles -1.0 -1.46908
CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K60175505 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09071
GSE190316,GSE190324_6_v_9_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null
CCAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31643
Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.181
KIF20A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53773
SOX11 ChEA Transcription Factor Targets 1.0 null
response to oxygen-containing compound GO Biological Process Annotations 2015 1.0 null
Midbrain central gray TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.293
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.11349
Dendrite terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.724
SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00305
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
MYC ENCODE Transcription Factor Targets 1.0 null
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-339-RBPJ_RBPJ Rummagene Transcription Factor Associations 2026 1.0 null
[PHAA1,D-TYR(ET)2,LYS6,DES-GLY9]AVP DGIdb Drug Targets 2026 1.0 0.420095
METTL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72314
Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.26468
females GeneRIF Biological Term Annotations 1.0 null
CD4+_Tcells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.845201
BRD-K10849007 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26289
NB10 DepMap CRISPR Gene Dependency 1.0 2.38638
Perturb_14307_KD_SRSF1_SRP230637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0
Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.727
H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null
MAPK1_knockdown_145_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.34738
Acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.367
GSE151612_0_v_2_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null
Parasympathetic nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.018
H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Pons TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.616
BRD-K33371292 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51925
FOXA1-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
Acromegaly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.365
CRCGN010_HEPG2_24H:H08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.83244
REST JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.8225
Ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.07
Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.432
nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.22692
regulation of phospholipase c activity GO Biological Process Annotations 2015 1.0 null
GSE239844_6_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null
Neuron projection terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.624
H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
EW8 CCLE Cell Line Gene Expression Profiles 1.0 1.69186
islets GeneRIF Biological Term Annotations 1.0 null
boldine-4122 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
PCF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41587
RNF14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49322
H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PMC5118094__F3 PFOCR Pathway Figure Associations 2024 1.0 null
Thorny excrescence COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.518
JHOS2 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049
CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155
Lateral ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.802
Alcohol Dependence, Protection Against DisGeNET Gene-Phenotype Associations 1.0 null
JUND ENCODE Transcription Factor Targets 1.0 null
breast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058009
BRD-K69423881 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85236
GSE234340_1_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null
SUPM2 CCLE Cell Line Gene CNV Profiles 1.0 2.70409
g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null
nucleotide-excision repair factor 1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.261
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
positive regulation of carbohydrate metabolic process GO Biological Process Annotations 2023 1.0 null
adrenal gland hyperfunction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.05429
BRD-K09523238 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14872
muscle GTEx Tissue Gene Expression Profiles -1.0 -1.30104
ACYP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02985
BRD-K89574562 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04531
H3K27me3_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K07001848 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72135
EXOSC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02704
BRD-K25236390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07894
D[PEN1,TYR(ME)2]AVP DGIdb Drug Targets 2026 1.0 0.420095
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
G protein-coupled receptor dimeric complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.141
NSMCE4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28146
valproic acid-346 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
PHF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96225
UBXN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9156
SYPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88749
guanabenz-2045 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
BRD-K40361885 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13215
embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053286
ZNF714 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10606
NOMO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35034
Anemia, Hemolytic CTD Gene-Disease Associations 1.0 1.30208
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K76885311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20357
BRD-K45860594 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6361
ZFP14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 89.1951
ZNF28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37156
Signaling by GPCR Reactome Pathways 2014 1.0 null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null
ABL1_knockdown_137_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.47568
CCNYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61697
Gonadotrophic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.861
Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.486
epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.144455
CRCGN017_MCF10A.WT.HP_24H:K22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.80755
CRCGN017_MCF10A.WT.HP_24H:N02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.00395
Zona fasciculata TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.349
BRD-K84235037 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02768
PF-00875133-00-5923 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SMZ1 DepMap CRISPR Gene Dependency 1.0 4.44946
positive regulation of hydrolase activity GO Biological Process Annotations 2015 1.0 null
CEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09549
BRD-K01077691 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.35995
novobiocin-435 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
ABL1_knockdown_144_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.21519
BRD-K59402582 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02404
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
positive regulation of phospholipase C activity GO Biological Process Annotations 2023 1.0 null
adult TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.265038
TAF2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null
docosahexaenoic acid ethyl ester-664 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
TIMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21922
GSE48812_2_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null
Overnutrition DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.305
YM 471 DGIdb Drug Targets 2026 1.0 0.420095
valinomycin-5906 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
BRD-K54903703 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5152
AG-013608-5904 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
MAFK_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
STK17A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86404
BRD-K71184289 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54402
child GeneRIF Biological Term Annotations 1.0 null
SNU1033 CCLE Cell Line Gene Expression Profiles -1.0 -1.89275
SRRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74395
Primary dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.097
transport across blood-brain barrier GO Biological Process Annotations 2025 1.0 null
H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
G protein-coupled peptide receptor activity GO Molecular Function Annotations 2025 1.0 null
H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.83877
DV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960218
dVDAVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
pituitary GTEx Tissue Gene Expression Profiles 1.0 2.17606
BRD-A17687311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63199
BRD-K09468701 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.20364
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
COIL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22744
d(CH2)5[Tyr(Et)2 Val4 des-Gly9]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.339
ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
NSL complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.648
H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K53772256 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03973
U343 CCLE Cell Line Gene Expression Profiles 1.0 1.55161
BRD-K05657319 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00811
ASRGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01882
clozapine-416 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
BRD-K07164317 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.92722
Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against DisGeNET Gene-Phenotype Associations 1.0 null
ARL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05959
BRD-K43388152 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20666
SORBS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87988
CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K27me3_CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
BRD-K75904236 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40081
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Quinazolines CTD Gene-Chemical Interactions 1.0 null
HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PARP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60573
SP1 ENCODE Transcription Factor Targets 1.0 null
APEX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.68043
Stress, Psychological HuGE Navigator Gene-Phenotype Associations 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Ventromedial hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.522
determination GeneRIF Biological Term Annotations 1.0 null
CALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51855
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
Pituitary gonadotropin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.482
DSEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63828
Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.371994
BRD-K54639145 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58168
GSE172016_2_v_0_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null
KLLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70632
increase GeneRIF Biological Term Annotations 1.0 null
H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
CACYBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00997
BRD-K18313650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12869
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
adenohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.50906
BRD-K93726930 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19614
CNN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77791
CAND2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5071
GSE148692,GSE148695_1_v_0_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null
CMLT1 CCLE Cell Line Gene Expression Profiles -1.0 -2.49034
RBM28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13269
H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
JHUEM1 DepMap CRISPR Gene Dependency 1.0 4.71318
ZNF382 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18596
H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
DTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61969
H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
GSE145915_5_v_4_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null
External plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.03
GABARAPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2442
PGAM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87612
Mood Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null
ZBTB20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88073
GPC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84227
GSE142232,GSE142234_0_v_3_gcgr_mouse RummaGEO Gene Perturbation Signatures 1.0 null
PKDCC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03562
increased susceptibility to pharmacologically induced seizures MGI Mouse Phenotype Associations 2023 1.0 null
TOMM40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69891
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON Rummagene Transcription Factor Associations 2026 1.0 null
hip TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.269174
ARNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05284
ZCCHC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77646
RELCOVAPTAN DGIdb Drug Targets 2026 1.0 0.180041
Alcohol use disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.421
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null
KE39 CCLE Cell Line Gene CNV Profiles -1.0 -1.47027
496100544_PCx_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.263
PSMF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27159
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
NBEAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7913
RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4722
lung carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.35082
cellular_component GO Cellular Component Annotations 2015 1.0 null
H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
Renal medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.295
GSE173394_1_v_0_nfatc2_human RummaGEO Gene Perturbation Signatures 1.0 null
YM 218 Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
mammalian phenotype MPO Gene-Phenotype Associations 1.0 null
H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
GSE121866_0_v_2_six4_human RummaGEO Gene Perturbation Signatures 1.0 null
SOHLH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51278
CYCLOPENTYLADENOSINE DGIdb Drug Targets 2026 1.0 0.180041
psychotic GeneRIF Biological Term Annotations 1.0 null
nervous system phenotype MPO Gene-Phenotype Associations 1.0 null
ZNF652-21678463-ZR75-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BEND4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4728
BRD-K44421266 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13194
ZNF81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19508
Grb2-EGFR complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.862
CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28526
MPND CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23914
BRD-K57937572 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40333
BRD-K22789469 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51571
H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
Lung adenocarcinoma_LUAD_TCGA-MP-A4SY-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
peptide binding GO Molecular Function Annotations 2015 1.0 null
Infundibular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.706
LIPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58598
MRPL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5755
Prostate adenocarcinoma_PRAD_TCGA-M7-A720-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
receptors GeneRIF Biological Term Annotations 1.0 null
d[Cha4]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
D[CHA4]AVP DGIdb Drug Targets 2026 1.0 0.315071
Forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.33
report GeneRIF Biological Term Annotations 1.0 null
H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null
MCAS COSMIC Cell Line Gene Mutation Profiles 1.0 null
HDAC6 ENCODE Transcription Factor Targets 1.0 null
GSE160817_7_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null
mucus layer COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.508383
Hepatomegaly CTD Gene-Disease Associations 1.0 1.22979
intracellular organelle GO Cellular Component Annotations 2015 1.0 null
H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
response to chemical GO Biological Process Annotations 2015 1.0 null
BRD-K41192699 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05819
ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5974
Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.276
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Guanylate cyclase complex, soluble COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.899
H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null
pituitary-dependent Cushing's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.138
H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
Sarcoma_SARC_TCGA-DX-A1KU-01A-32R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
TFPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30625
NCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93274
infundibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.499223
Drug-Related Side Effects and Adverse Reactions CTD Gene-Disease Associations 1.0 1.38384
ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9297
SPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26462
cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040939
AHCY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97664
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TT-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Melancholic depression DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.929
CRCGN016_MCF10A.TP53.M_24H:O18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.57697
Psychotic Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null
Medial temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.671
BRD-K55505527 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10089
NELFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41357
PTGIS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84222
UACC812 CCLE Cell Line Gene CNV Profiles 1.0 2.2299
HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -2.51634
PELI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99235
GSE60837_6_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null
pg4 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.584
GSE93674_2_v_0_ezh2_mouse RummaGEO Gene Perturbation Signatures 1.0 null
decreased aggression MGI Mouse Phenotype Associations 2023 1.0 null
BRD-K78668110 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0392
involvement GeneRIF Biological Term Annotations 1.0 null
CRCGN014_HEPG2_24H:N12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.15434
UBE2G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88604
C18orf54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51912
Attention Deficit Disorder with Hyperactivity HuGE Navigator Gene-Phenotype Associations 1.0 null
H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
EBF1-22473956-LYMPHODE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
regulation of systemic arterial blood pressure mediated by a chemical signal GO Biological Process Annotations 2015 1.0 null
EID3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82615
INA6 DepMap CRISPR Gene Dependency 1.0 3.21968
SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K95922469 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24194
valproic acid-433 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
PHGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1751
H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PFKFB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62546
U20S BioGPS Cell Line Gene Expression Profiles 1.0 1.89634
H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
SR 121463 DrugBank Drug Targets 1.0 null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Phobic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.299
intracellular part LOCATE Curated Protein Localization Annotations 1.0 null
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF Rummagene Transcription Factor Associations 2026 1.0 null
THAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7665
BRD-K02159857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05372
OXT Guide to Pharmacology Protein Ligands of Receptors 1.0 null
PMC8985862-Table3.XLSX-OTP-BRCA1_OTP Rummagene Transcription Factor Associations 2026 1.0 null
ECHS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13298
ETV5::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.8612
central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.26844
Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.424
Caudate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.936
BRD-K77241556 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05703
Central amygdaloid nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.63
BRD-K61973443 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25847
HES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7924
TMEM167B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50386
Vasopressin-like receptors Reactome Pathways 2014 1.0 null
polymorphisms GeneRIF Biological Term Annotations 1.0 null
Habenula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.19
membrane GO Cellular Component Annotations 2015 1.0 null
PDPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70734
SUPT4H1 MSigDB Cancer Gene Co-expression Modules 1.0 null
hexestrol-6077 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.08459
CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Soluble ACE2 mediated cell entry of SARS CoV 2 WikiPathways Pathways 2024 1.0 null
d[Cha4]LVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.164149
GSE164494_1_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null
regulation of cell population proliferation GO Biological Process Annotations 2023 1.0 null
endosome GO Cellular Component Annotations 2015 1.0 null
MGAT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65239
zardaverine-2926 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K64704925 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41761
Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.146
AVP Pathway Commons Protein-Protein Interactions 1.0 null
CAB39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64735
abnormal social/conspecific interaction MPO Gene-Phenotype Associations 1.0 null
BRD-K85604751 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24214
[TBAA1,D-TYR(ET)2,VAL4,LYS6,ARG-NH28,DES-GLY9]AVP DGIdb Drug Targets 2026 1.0 0.420095
Nucleus solitarius TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.815
DNAJC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37844
Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI) Reactome Pathways 2024 1.0 null
H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
positive regulation of cytosolic calcium ion concentration GO Biological Process Annotations 2015 1.0 null
BRD-K17367110 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60103
Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.676
SDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29038
SPRING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79308
regulation of phospholipase activity GO Biological Process Annotations 2015 1.0 null
g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null
H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
[Phaa1 D-Tyr2 Val4 Arg6 Arg-NH29]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
ZNF212 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75776
PIAS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00057
ANKRD34B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36296
ZFP42-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null
urinary system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.319863
LRAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39744
pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.3868
PU.1-20513432-BCELLS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
BRD-K18864235 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08441
Cerebellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.584
Sympathetic nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.253
EIF3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38959
P53-21459846-SAOS-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
BRD-K28429328 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.65159
hsa-miR-3176 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663
PUS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40058
H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null
Vasopressin HMDB Metabolites of Enzymes 1.0 null
CRCGN016_MCF10A.TP53.M_24H:N14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.88915
OSR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4679
positive regulation of vasoconstriction GO Biological Process Annotations 2025 1.0 null
GSE160817_7_v_9_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null
PK59 CCLE Cell Line Gene CNV Profiles -1.0 -1.98792
MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null
hypophysis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
RPS4X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60627
GSE164494_0_v_2_rab22a_mouse RummaGEO Gene Perturbation Signatures -1.0 null
CRCGN013_HEPG2_24H:L20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.22395
intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null
Oligospermia CTD Gene-Disease Associations 1.0 1.15492
VDAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98893
H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
MIDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76037
NCI-H226Br cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.118
H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
RARA::RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.6206
alter GeneRIF Biological Term Annotations 1.0 null
SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21514
H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null
SW1271 CCLE Cell Line Gene CNV Profiles -1.0 -1.65294
FFAR4_KO_GDS4811_507_mouse_adipose GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
PSMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61534
Cutaneous adenocystic carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155
Postpartum depression DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.589
Nasal cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.209
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
PAX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1181
NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null
heterodimers GeneRIF Biological Term Annotations 1.0 null
NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948179
GSE151612_0_v_7_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null
CTBP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2144
deficit GeneRIF Biological Term Annotations 1.0 null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null
CERS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2097
Antisocial personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.281
obsessive-compulsive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.242
BRD-K40019775 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63127
PUSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40921
ZKSCAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84941
limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.888829
NCI-H82 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.742
STOCK1N-28457-6864 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
single-multicellular organism process GO Biological Process Annotations 2015 1.0 null
SAFB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86909
496100518_HIP_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.22553
GSE211151_1_v_0_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null
ATCAY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25933
BRD-K53634892 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27951
H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
DHX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98672
NCOA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8971
nucleotide-excision repair factor 3 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.749
SOHLH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77081
pioglitazone-5925 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
cellular response to organic substance GO Biological Process Annotations 2015 1.0 null
PAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2768
JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
MANBA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98959
Suprachiasmatic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.826
H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null
BRD-K05902089 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06702
BRD-A95239561 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45173
depression GeneRIF Biological Term Annotations 1.0 null
Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.80303
X-linked nephrogenic diabetes insipidus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.262
PNKP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47234
PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null
g-protein coupled peptide receptor activity GO Molecular Function Annotations 2015 1.0 null
RAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43237
SP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.107
RL95-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null
MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
regulation of biological process GO Biological Process Annotations 2015 1.0 null
Primary hyperaldosteronism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.075
SUPM2 DepMap CRISPR Gene Dependency 1.0 7.45523
MERO82 DepMap CRISPR Gene Dependency 1.0 2.30054
ROCK_INHIBITION_GDS3944_464_mouse_Forebrain astrocytes - 24 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
Lateral habenular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.598
CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.81701
membrane GeneRIF Biological Term Annotations 1.0 null
YMB1 CCLE Cell Line Gene CNV Profiles 1.0 1.99811
vasopressin receptor activity GO Molecular Function Annotations 2023 1.0 null
P53-22387025-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
ZCWPW1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36283
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_H_sapiens_970_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null
H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
HYAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24503
DEL CCLE Cell Line Gene CNV Profiles 1.0 1.72096
Heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.205
CRCGN015_MCF10A.WT.HP_24H:K18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.20661
GSE68156_3_v_5_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null
GSE239844_11_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null
BRD-K97223487 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24188
BRD-K51522005 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68556
ACACA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27565
CRCGN014_HEPG2_3H:D20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.33652
MCF7 CCLE Cell Line Gene CNV Profiles 1.0 1.37735
NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32035
BRD-A90249268 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12769
STX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01859
Hypertrophy CTD Gene-Disease Associations 1.0 1.06952
CD19+_BCells(neg._sel.) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.97591
BATF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24479
CRCGN008_HEPG2_24H:A16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.221
G361 CCLE Cell Line Gene CNV Profiles -1.0 -1.56725
cytoplasmic part GO Cellular Component Annotations 2015 1.0 null
PLEKHG4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11155
protein kinase C binding GO Molecular Function Annotations 2023 1.0 null
Medial entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.72
FOSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4719
CTCF ENCODE Transcription Factor Targets 1.0 null
BRD-K60047946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79812
Hypophysis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
NDUFAF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63265
bone marrow HPA Tissue Protein Expression Profiles -1.0 -1.90005
[PHAA1,D-TYR2,VAL4,ARG6,ARG-NH29]AVP DGIdb Drug Targets 2026 1.0 0.420095
plasma membrane GO Cellular Component Annotations 2015 1.0 null
Autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.185
PPFIA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66141
performed GeneRIF Biological Term Annotations 1.0 null
Pedal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.878
H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046264
MORN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11981
H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
positive regulation of intracellular signal transduction GO Biological Process Annotations 2025 1.0 null
Piriform area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.55
KLF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09207
A2780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04947
JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.981607
BICR31 DepMap CRISPR Gene Dependency 1.0 2.28056
Caudate putamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.354
ATN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37464
Fasciolar gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.576
hormonal GeneRIF Biological Term Annotations 1.0 null
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null
Fibrosis CTD Gene-Disease Associations 1.0 1.10246
RIMS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30722
REST ENCODE Transcription Factor Targets 1.0 null
BRWD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26258
Limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.372
PEX11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5578
CLEC2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81824
MDA MB435 BioGPS Cell Line Gene Expression Profiles -1.0 -2.60409
BRD-K44946060 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15265
EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CP50-MEL-B COSMIC Cell Line Gene Mutation Profiles 1.0 null
abnormal circulating androgen level MPO Gene-Phenotype Associations 1.0 null
SIPA1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73039
BRD-K27058632 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.03352
H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
melancholic GeneRIF Biological Term Annotations 1.0 null
RBE DepMap CRISPR Gene Dependency 1.0 3.64622
ZNF681 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25048
COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00651
caudate putamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.420385
FLT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12507
Autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.22
PROP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44557
Trigeminal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.86
attempt GeneRIF Biological Term Annotations 1.0 null
BRD-K53489056 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.08127
Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null
BRD-A20213616 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37673
tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null
BBLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.85485
Preoptic area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.024
CPSF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53046
POU2AF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11033
BRD-K00086692 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32058
Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.214
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null
Disease Models, Animal HuGE Navigator Gene-Phenotype Associations 1.0 null
496100623_PCx_no dementia_TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.37379
KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10325
Teratocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.333
membrane LOCATE Curated Protein Localization Annotations 1.0 null
plasma GeneRIF Biological Term Annotations 1.0 null
positive regulation of icosanoid secretion GO Biological Process Annotations 2025 1.0 null
Growth hormone secreting pituitary adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.039
CRCGN008_HEPG2_24H:L12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0657
CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07867
Depressed Mood DisGeNET Gene-Phenotype Associations 1.0 null
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
BRD-K07160586 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28594
Intermittent explosive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.112
UBE2F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62849
presence GeneRIF Biological Term Annotations 1.0 null
APLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76981
cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null
Peptide GPCRs(Homo sapiens) WikiPathways Pathways 2014 1.0 null
CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
COGN305 DepMap CRISPR Gene Dependency 1.0 2.25911
ELP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13294
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
ZNHIT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76061
positive regulation of phospholipase activity GO Biological Process Annotations 2015 1.0 null
GSE152441,GSE152442_7_v_3_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null
hsa-miR-4688 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969
BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947113
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
cellular response to organic substance GO Biological Process Annotations 2023 1.0 null
Prefrontal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.738
PSAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70945
ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null
Adrenal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.3
Olfactory tubercle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.956
CD8+_Tcells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.863727
SP100 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27229
PCGF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79321
MTHFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11315
TMEM17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01882
PC3 CCLE Cell Line Gene CNV Profiles 1.0 1.73496
b18 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.604
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
D(CH2)5[TYR(ET)2,VAL4,DES-GLY9]AVP DGIdb Drug Targets 2026 1.0 0.420095
H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
P3H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45626
BRD-K66734120 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11441
ZNF736 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60448
Perturb_754_OE_METTL3_SRP393226 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.23179
Basal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.985
BRD-K04618303 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16649
APAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.57162
CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
increased circulating testosterone level MGI Mouse Phenotype Associations 2023 1.0 null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
TNFSF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81752
SNAPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80207
crhr1 GeneRIF Biological Term Annotations 1.0 null
HOMER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61323
ZNF835 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37121
NCVADR RES BioGPS Cell Line Gene Expression Profiles -1.0 -1.10596
Perturb_2388_KO_CARM1_SRP333775 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.62017
NCIH2887 DepMap CRISPR Gene Dependency 1.0 2.13047
H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null
EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
responses to psychosocial stress GAD Gene-Disease Associations 1.0 null
regulation of MAPK cascade GO Biological Process Annotations 2025 1.0 null
Amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.322
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Abdominal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.663
CRCGN015_MCF10A_48H:E21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.02811
LN443 CCLE Cell Line Gene Expression Profiles 1.0 1.36867
PLEKHN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38735
Lung adenocarcinoma_LUAD_TCGA-69-8254-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
cognitive impairment GWASdb SNP-Phenotype Associations 1.0 0.522136
BRD-K63921431 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26084
Serotonin receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.932
acth-secreting pituitary adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.11351
BRD-K74641261 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14253
B3GNT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56531
CD14+_Monocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.042
BRD-K77354700 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00885
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K29898553 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15505
JHESOAD1 CCLE Cell Line Gene Expression Profiles 1.0 1.58463
MTRR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6867
psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.257358
Nephrogenic diabetes insipidus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.045
UBXN8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23421
ZNF445 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15565
BHLHE41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14261
DPYSL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33538
positive regulation of blood circulation GO Biological Process Annotations 2015 1.0 null
NCIH650 CCLE Cell Line Gene CNV Profiles -1.0 -1.54295
HMGXB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66907
GSE68156_0_v_1_dextran_mouse RummaGEO Drug Perturbation Signatures -1.0 null
H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K11399565 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30623
H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Golgi apparatus COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0
CCDC74A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67881
CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
decreased circulating corticosterone level MGI Mouse Phenotype Associations 2023 1.0 null
Zona glomerulosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.87
HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.878565
BRD-K95323025 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16077
HDQP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.51664
protein kinase binding GO Molecular Function Annotations 2023 1.0 null
BRD-K45717258 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1981
Shock, Septic HuGE Navigator Gene-Phenotype Associations 1.0 null
vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053472
Recurrent Major Depressive Episodes DisGeNET Gene-Disease Associations 1.0 null
Myometrial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.073
etofylline-5467 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Substance dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.504
cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
panic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.524588
ZNF697 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12685
BRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38033
TAL1 ENCODE Transcription Factor Targets 1.0 null
Perturb_2981_KD_ISG_SRP158414 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.0698
GSE195663_0_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null
CRCGN008_HEPG2_24H:L15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.2985
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null
H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K36909552 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.15935
Disorders of transmembrane transporters Reactome Pathways 2024 1.0 null
IRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41346
membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null
H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
mozavaptan Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Insular cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.303
H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
AGO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.046
BRD-A39900448 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11961
hippocampal pyramidal layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.335233
Borderline personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.728
first GeneRIF Biological Term Annotations 1.0 null
H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
PMC11568168-41598_2024_79607_MOESM3_ESM.xls-11-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null
GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null
CRCGN015_MCF10A.WT.HP_24H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.06929
genetic GeneRIF Biological Term Annotations 1.0 null
CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GSE109285_3_v_2_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null
CRCGN014_HEPG2_24H:F08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.10608
H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null
MTCH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.29368
CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K30962012 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1345
cinnarizine-5817 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
DVDAVP DGIdb Drug Targets 2026 1.0 0.420095
suicide GeneRIF Biological Term Annotations 1.0 null
trovafloxacin_homo sapiens_gpl96_gse9166 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
binding GO Molecular Function Annotations 2015 1.0 null
BRD-K69879051 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57058
GPCR downstream signalling Reactome Pathways 2024 1.0 null
SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null
M6PR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28552
resveratrol-662 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
YM 218 DGIdb Drug Targets 2026 1.0 0.420095
Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.131
Accessory olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.753
BRD-K82409466 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64382
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
external plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.487106
PTGES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63084
H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
BRD-K26603007 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04926
H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA Rummagene Transcription Factor Associations 2026 1.0 null
H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K45740917 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00277
Pituitary blastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011
phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028359
CCNF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95201
Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CRCGN015_HEPG2_48H:B21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.03018
Sarcoma_SARC_TCGA-IW-A3M4-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CFAP298 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50696
asperger syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.964148
BRD-K55393423 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48313
SPI1 ENCODE Transcription Factor Targets 1.0 null
regulation of systemic arterial blood pressure by vasopressin GO Biological Process Annotations 2015 1.0 null
UROD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66679
BRD-K06997715 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58564
intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.280349
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR Rummagene Transcription Factor Associations 2026 1.0 null
MALME 3M BioGPS Cell Line Gene Expression Profiles -1.0 -1.53322
CRCGN016_MCF10A.TP53.M_24H:P16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.40978
PLAG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 112.389
H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
C17orf107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27304
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342
KCL-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null
d(CH2)5[Tyr(Me)2 Thr4 Tyr-NH29]OVT Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
divalent inorganic cation homeostasis GO Biological Process Annotations 2015 1.0 null
SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null
496100368_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.1916
PHC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82962
TERLIPRESSIN DGIdb Drug Targets 2026 1.0 1.26029
Substance abuse DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.648
H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null
BRD-A88691416 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.20235
Nucleus preopticus medianus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.22
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null
GSE225901_2_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null
Hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.565
BRD-K74039237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37525
ACTH-secreting pituitary adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.177
response to nitrogen compound GO Biological Process Annotations 2015 1.0 null
GSE240386,GSE242143_1_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null
KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
LASP1NB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80581
Granular vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.623
intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null
membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
adhd ; attention-deficit hyperactivity disorder GAD Gene-Disease Associations 1.0 null
Mental Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null
928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00447
CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Anterior chamber of the eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.535
nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.294939
RING1 MSigDB Cancer Gene Co-expression Modules 1.0 null
regulation of arachidonate secretion GO Biological Process Annotations 2025 1.0 null
GPCR ligand binding Reactome Pathways 2014 1.0 null
Phospholipase D signaling pathway KEGG Pathways 2026 1.0 null
habenula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.261624
LS-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null
EPLC272H CCLE Cell Line Gene Expression Profiles 1.0 1.99876
Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.4934
HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6448
Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 69.8413
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-02A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
small adrenal glands MGI Mouse Phenotype Associations 2023 1.0 null
GRK5 Pathway Commons Protein-Protein Interactions 1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
INKA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26083
BRAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25229
cytoplasmic vesicle LOCATE Curated Protein Localization Annotations 1.0 null
intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.320077
D[D-PAL2]AVP DGIdb Drug Targets 2026 1.0 0.420095
PEPD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96664
D(CH2)5[TYR(ME)2,THR4,TYR-NH29]OVT DGIdb Drug Targets 2026 1.0 0.315071
HDAC1 ENCODE Transcription Factor Targets 1.0 null
seizures MPO Gene-Phenotype Associations 1.0 null
NKIRAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79763
regulation of vasoconstriction GO Biological Process Annotations 2023 1.0 null
CRCGN017_MCF10A.WT.HP_24H:P10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5116
Subesophageal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.666
d(CH2)5[Tyr(Me)2]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Coronavirus infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.429
CATH.a cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.655
BRD-K29756429 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55306
MCF 10A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960218
d[Pen1 Tyr(Me)2]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
GSE48812_7_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null
BRD-K81439435 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50354
ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K24825509 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24514
Autonomic nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.449
abnormal adrenocorticotropin level MPO Gene-Phenotype Associations 1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-01A-02R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.02089
PIK3R3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05113
MAGEB17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42601
AOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04487
MDAMB453 DepMap CRISPR Gene Dependency 1.0 2.45158
BRD-K51970157 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.26994
BRD-K62625902 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19536
CRCGN011_HEPG2_24H:K07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.0657
BRD-K98321674 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34045
TTLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03314
PKD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31307
ETS1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K84423439 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10463
anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.383337
Stria terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.262
NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03261
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-A68797623 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6203
Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.703
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA Rummagene Transcription Factor Associations 2026 1.0 null
cellular response to endogenous stimulus GO Biological Process Annotations 2015 1.0 null
Functioning pituitary adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.943
Kidney failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097
G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947113
BRD-K62511698 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34352
APLP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04737
ZNF263 ENCODE Transcription Factor Targets 1.0 null
BRD-K53354260 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46712
H3K4me1_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Adrenal gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.015
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null
BRD-K22229373 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.61654
Signal Transduction Reactome Pathways 2024 1.0 null
GSE264621_1_v_3_secretin_human RummaGEO Drug Perturbation Signatures -1.0 null
ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.8379
GSE109140_2_v_1_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null
endocrine pancreas disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.112405
Anterior lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.691
Cornu ammonis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.295
Perturb_14680_KO_P2Y14_SRP044222 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.26578
skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052115
LK-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null
BRD-K02707544 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07507
H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.92985
KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
positive regulation of arachidonic acid secretion GO Biological Process Annotations 2023 1.0 null
GSE231799_3_v_4_nfkbie_mouse RummaGEO Gene Perturbation Signatures -1.0 null
Hemocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.309
KCTD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07083
OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50651
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.505
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3373-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CLCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17448
BRD-K63415335 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5656
TSPO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25941
bacitracin-6488 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Cerebrovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.138
DFFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03951
[Val4]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
G28T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910533
GSE172016_2_v_1_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null
Bonemarrow BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.07448
MRPS27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06858
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null
disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.521117
CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K62102480 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54097
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
SNCA_KO_GDS4153_528_mouse_cerebellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
Pituitary gland tumor cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.502
features GeneRIF Biological Term Annotations 1.0 null
GATA1-19941827-MEL86-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.00807
BNIP1 MSigDB Cancer Gene Co-expression Modules 1.0 null
RNF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07091
H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Polycystic kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.396
increased susceptibility to pharmacologically induced seizures MPO Gene-Phenotype Associations 1.0 null
UMUC3 CCLE Cell Line Gene CNV Profiles -1.0 -2.07477
Perturb_14391_KD_PAX8_SRP276625 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0
Preputial gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.72
SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.446
UBR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81305
AMO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.89861
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EK-01A-22R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Perturb_14305_KD_HNRNPM_SRP230637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.63817
GSE211151_1_v_4_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null
PMC12268429-ao5c02585_si_001.pdf-7-TBX19_TBX19 Rummagene Transcription Factor Associations 2026 1.0 null
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SOX11-23321250-Z138-A519-JVM2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
napelline-6084 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-A04231641 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87839
GSE120413,GSE120447_0_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null
RAD21 ENCODE Transcription Factor Targets 1.0 null
flunisolide-3828 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
membrane part GO Cellular Component Annotations 2015 1.0 null
intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
atosiban Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Neural lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.803
CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
AGAP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57787
furaltadone-4313 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Fragile X syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.041
GSE152441,GSE152442_7_v_4_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null
CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CTCF_HEK293_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
haloperidol-492 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
ZNF609 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52911
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4174-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K28512751 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7362
CCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52076
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK Rummagene Transcription Factor Associations 2026 1.0 null
tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.7209
SPARC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43192
FAM193B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34856
MAVER1 DepMap CRISPR Gene Dependency 1.0 2.84783
Infertility, Male CTD Gene-Disease Associations 1.0 1.03976
abnormal social investigation MPO Gene-Phenotype Associations 1.0 null
BRD-K37592272 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82528
CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null
Cerebellum TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K71424148 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.75814
cell part GO Cellular Component Annotations 2015 1.0 null
BRD-K75048204 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.75574
BRD-K90127324 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07878
Cingulate cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.394
disease of mental health GWASdb SNP-Disease Associations 1.0 0.0446
PHF8-20622853-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
flumetasone-4734 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
cellular ion homeostasis GO Biological Process Annotations 2015 1.0 null
adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.171785
major depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.10048
KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SCMH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12993
deferoxamine-mesylate LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12344
ETS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0526
OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09728
whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3642
SRY-22984422-TESTIS-RAT ChEA Transcription Factor Binding Site Profiles 1.0 null
BRD-K09511124 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02754
DDX31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36069
ZNF678 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34909
supraoptic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.660304
CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
positive regulation of intracellular signal transduction GO Biological Process Annotations 2023 1.0 null
Thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.253
BRD-K53396471 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15394
Perturb_3009_KD_HNF1alpha/HNF1beta_SRP067843 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.4004
regulation of MAPK cascade GO Biological Process Annotations 2023 1.0 null
intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
sodium phenylbutyrate-434 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
EGFR_druginhibition_82_GSE27638 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.69094
hypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.54632
brain stem TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null
BRD-K40765512 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16409
Pars intermedia TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.496
CRCGN012_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.63595
SAC3D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55826
pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.834788
MASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77132
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
MTG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26628
NUPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52993
Fatty Liver CTD Gene-Disease Associations 1.0 1.46172
SF172 CCLE Cell Line Gene Expression Profiles 1.0 2.12582
positive regulation of catalytic activity GO Biological Process Annotations 2015 1.0 null
SLC45A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70849
SATAVAPTAN DGIdb Drug Targets 2026 1.0 0.420095
Weight Gain CTD Gene-Disease Associations 1.0 1.23743
protein kinase c binding GO Molecular Function Annotations 2015 1.0 null
SR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882059
CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.52697
BRD-K44866331 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13581
H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
cloperastine-3710 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Nipple TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.924
Medial amygdaloid nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.032
abnormal adrenal gland morphology MPO Gene-Phenotype Associations 1.0 null
Brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.524
response to stimulus GO Biological Process Annotations 2015 1.0 null
Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.05
Cholestasis, Intrahepatic CTD Gene-Disease Associations 1.0 1.08091
H3K27me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null
GSE174498,GSE174500_0_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null
MON DepMap CRISPR Gene Dependency 1.0 2.64156
GSE142232,GSE142234_0_v_2_gcgr_mouse RummaGEO Gene Perturbation Signatures 1.0 null
Thyroid Diseases CTD Gene-Disease Associations 1.0 1.03345
G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.9123
Axon collateral COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.746
H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
intrinsic component of plasma membrane GO Cellular Component Annotations 2015 1.0 null
Communication disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.57
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
positive regulation of phosphate metabolic process GO Biological Process Annotations 2023 1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K77504251 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08946
GSE65617_5_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null
Dendritic knob COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.04
ZNF112 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6619
GSE163240_2_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null
ALDH1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99777
CRCGN014_HEPG2_24H:P01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.37077
CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SERINC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01383
GSE133329_0_v_3_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null
Urogenital Abnormalities CTD Gene-Disease Associations 1.0 1.42293
SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PPM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36129
cation homeostasis GO Biological Process Annotations 2015 1.0 null
post-traumatic stress disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.708
KOSC2 DepMap CRISPR Gene Dependency 1.0 5.8492
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CLDND2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27787
H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null
RASSF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01859
IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.5437
TTLL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10914
CRCGN011_HEPG2_24H:K01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.5424
MED20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99742
endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.11022
Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.183
NKX2-4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15422
D542MG DepMap CRISPR Gene Dependency 1.0 2.19191
SLR20 CCLE Cell Line Gene Expression Profiles 1.0 1.64003
pituitary gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.078409
Prelimbic cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.941
mood GeneRIF Biological Term Annotations 1.0 null
monastrol-681 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
ZNF692 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4311
H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K04468899 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00614
PMC3500769-srep00875-s3.xls-AP1-Time_4_JUN Rummagene Transcription Factor Associations 2026 1.0 null
anterior lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.54826
PPP2R2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.20969
CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null
624 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835055
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null
BRD-K46824282 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53963
cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043402
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
SAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08863
BRD-A04258855 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35013
H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
NCIH1836 CCLE Cell Line Gene Expression Profiles -1.0 -1.63874
ANO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98517
cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.422782
CDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.48134
RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Peptide ligand-binding receptors Reactome Pathways 2014 1.0 null
YM 471 Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Prestwick-674-3716 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
PNPLA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38109
CRCGN009_HEPG2_24H:K13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.89215
IMP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2614
INSYN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50388
Neuroendocrine tumor cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.661
SPECC1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73963
EBF1-22473956-BONE-MARROW-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
JURKAT CCLE Cell Line Gene Expression Profiles -1.0 -2.3318
plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342
telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.693719
PCGF2-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K06611347 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27788
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5695-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
G protein-coupled receptor heterodimeric complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.212
TMEM187 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8381
EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
E2A MotifMap Predicted Transcription Factor Targets 1.0 null
CBX2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
functioning pituitary adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.761862
gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.11818
FRAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41873
FANCC MSigDB Cancer Gene Co-expression Modules 1.0 null
serotonin-activated cation-selective channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.567
ECC12 CCLE Cell Line Gene CNV Profiles 1.0 1.43666
OCUB-M COSMIC Cell Line Gene Mutation Profiles 1.0 null
ANXA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66846
MEIS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77985
increased susceptibility to induction of seizure by inducing agent MPO Gene-Phenotype Associations 1.0 null
NDUFA10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18045
CRCGN015_HEPG2_48H:A07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.67501
estradiol-5905 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
UFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82697
PIN1_DEPLETION_GDS4070_450_human_MDA-MB-231 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
NO-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null
Myelencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.358
Lung adenocarcinoma_LUAD_TCGA-05-4244-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
POGLUT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26761
Mitral cell layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.06
BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40467
SNUC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.60905
corpus striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.168752
GM97 BioGPS Cell Line Gene Expression Profiles -1.0 -0.985513
H3K27me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
UOK101 CCLE Cell Line Gene Expression Profiles 1.0 1.65697
Vascular smooth muscle contraction KEGG Pathways 2026 1.0 null
D(CH2)5[TYR(ME)2]AVP DGIdb Drug Targets 2026 1.0 0.315071
Prader-Willi syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.355
ZNF283 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91539
AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948179
OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09728
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.424
POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4127
BRD-K40612106 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67159
ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 81.0097
H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
pancreas disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.080018
GSE239844_4_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null
ZBTB24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.622
BRD-K25161864 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15727
DCAF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72686
MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14748
Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.297
SOX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4362
SMIM24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04497
FHOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37771
phenazone-1989 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Protein phosphatase inhibitor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.548
H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
ZNF143 ENCODE Transcription Factor Targets 1.0 null
CRCGN016_MCF10A.TP53.M_24H:K05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.7987
Liver Failure CTD Gene-Disease Associations 1.0 1.10527
BRD-K43674766 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10768
homo GeneRIF Biological Term Annotations 1.0 null
CRCGN015_HEPG2_48H:H19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.38241
obtaining GeneRIF Biological Term Annotations 1.0 null
NCIH1299 CCLE Cell Line Gene CNV Profiles -1.0 -1.55672
Corticotropic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.71
RNF169 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44182
JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15664
adrenal cortical hypofunction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.42139
H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
median eminence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.517678
nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.255834
SW403 COSMIC Cell Line Gene Mutation Profiles 1.0 null
niflumic acid-2399 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
G120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.981607
cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.48287
Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
cellular response to chemical stimulus GO Biological Process Annotations 2015 1.0 null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CAKI1 DepMap CRISPR Gene Dependency 1.0 4.69724
CRCGN014_HEPG2_24H:L17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.27646
monorden-544 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
BRD-K25736729 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.73325
TARBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57594
attention GeneRIF Biological Term Annotations 1.0 null
positive regulation of biological process GO Biological Process Annotations 2015 1.0 null
SCN4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21655
characterized GeneRIF Biological Term Annotations 1.0 null
KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08995
Infralimbic cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.77
tetrandrine-6082 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
metolazone-2014 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null
ZNF281 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 175.648
cellular response to stimulus GO Biological Process Annotations 2015 1.0 null
Mo-B cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.761
GRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77852
H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K90863245 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27668
positive regulation of alcohol biosynthetic process GO Biological Process Annotations 2025 1.0 null
Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
105KC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948179
T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21624
CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CHST12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60992
H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null
2-CHLOROADENOSINE DGIdb Drug Targets 2026 1.0 0.114571
ZNF461 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42581
CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
UNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75456
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null
Neurohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.134
mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.508808
SMIM20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89188
H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
GSE145249_1_v_3_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null
M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.29053
H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
ALKBH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10453
MRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34314
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Neostriatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.492
alleles GeneRIF Biological Term Annotations 1.0 null
JOSD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00043
H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.791044
calcium signaling pathway KEGG Pathways 1.0 null
Jaundice CTD Gene-Disease Associations 1.0 1.13143
H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
urinary tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.312232
Node of Ranvier COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.819
imatinib_homo sapiens_gpl96_gds3044 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
CRCGN017_MCF10A.WT.HP_24H:N22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.6017
AP1AR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84759
SLC27A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84733
PMC11236317-aging-16-205930-s001.pdf-1-CREB3_CREB3 Rummagene Transcription Factor Associations 2026 1.0 null
NUCB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37619
MDA-MB-175-VII COSMIC Cell Line Gene Mutation Profiles 1.0 null
N6-PHENYLADENOSINE DGIdb Drug Targets 2026 1.0 0.180041
MFE-296 COSMIC Cell Line Gene Mutation Profiles 1.0 null
GH3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.697
C-fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.89
ZNF320 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 196.694
astrocytes BioGPS Cell Line Gene Expression Profiles 1.0 1.10412
H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
NPAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21727
Renal tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.797
abnormal gland morphology MPO Gene-Phenotype Associations 1.0 null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1 Rummagene Transcription Factor Associations 2026 1.0 null
PTP4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52834
Bed nucleus of stria terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.563
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6484-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
SC-560-6865 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
BRD-K10189430 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4648
ZNF83 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12793
CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
integral component of plasma membrane GO Cellular Component Annotations 2015 1.0 null
DHX35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67497
ZNF652-21678463-ZR75-1-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null
BRD-K57719270 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05016
Pars distalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.065
NASP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28812
Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.471
Conduct disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105
regulation of systemic arterial blood pressure by vasopressin GO Biological Process Annotations 2023 1.0 null
GSE132408_0_v_3_tet2_human RummaGEO Gene Perturbation Signatures 1.0 null
MOV10L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36432
NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19748
vascular transport GO Biological Process Annotations 2025 1.0 null
BRD-K65183353 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23734
Myometrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.348
satavaptan Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-A89947015 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83977
CTV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null
ion homeostasis GO Biological Process Annotations 2015 1.0 null
BRD-K11726285 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00648
H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
OVMIU DepMap CRISPR Gene Dependency 1.0 4.05872
animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
ARGIPRESTOCIN DGIdb Drug Targets 2026 1.0 0.315071
LN382 CCLE Cell Line Gene Expression Profiles 1.0 1.39704
cellular response to hormone stimulus GO Biological Process Annotations 2015 1.0 null
H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K06330738 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33292
ALG12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87004
Nucleus preopticus medialis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.2
BRD-K90697693 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32775
BRD-K46291400 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56106
BRD-K74779337 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22438
BRD-K82882781 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03681
BRD-K30025024 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5641
20068086-ST1-4 GeneSigDB Published Gene Signatures 1.0 null
Habenular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.687
REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CRCGN012_HEPG2_24H:G19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.35252
Dense core granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.288
ZNF700 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12127
Paraventricular nucleus of hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.003
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Acute Kidney Injury CTD Gene-Disease Associations 1.0 1.12357
AK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.956
CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Weight Loss CTD Gene-Disease Associations 1.0 1.34694
neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.340757
cellular metal ion homeostasis GO Biological Process Annotations 2015 1.0 null
BCPAP GDSC Cell Line Gene Expression Profiles 1.0 1.42367
BRD-K90644597 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45751
MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null
BRD-K10459843 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10845
GSE163240_3_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null
nd7/23 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.897
HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881966
NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24462
Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091
ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CTCF-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K87340219 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52893
TOP1MT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7055
SCA1_Knock-in_GDS1756_233_mouse_Forebrain tissue - 4 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
G protein-coupled peptide receptor activity GO Molecular Function Annotations 2023 1.0 null
H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
22RV1 COSMIC Cell Line Gene Mutation Profiles 1.0 null
H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
regulation of vasoconstriction GO Biological Process Annotations 2025 1.0 null
TLNRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28686
DESMOPRESSIN DGIdb Drug Targets 2026 1.0 1.26029
BRD-K07152092 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27201
CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null
capsaicin-3372 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K22246901 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21527
CAAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32176
COMMD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87341
496100320_PCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.93642
BRD-K49640920 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00975
Vomeronasal organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.665
TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
JAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16874
paraventricular nucleus of hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.362646
KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
EWSR1-FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 355.162
Raphe nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.351
Mesolimbic dopaminergic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.595
Panic Disorder DisGeNET Gene-Disease Associations 1.0 null
ZFP42-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null
RFX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63176
d[Cha4 Dab8]VP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
WERIRB1 DepMap CRISPR Gene Dependency 1.0 3.31303
Circumventricular organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.121
Hippocampal mossy fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.525
Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.7053
U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38522
HCC1187 DepMap CRISPR Gene Dependency 1.0 2.83548
Renal distal tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.181
POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
HCC78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03848
BRD-K91998226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00951
SMC3 ENCODE Transcription Factor Targets 1.0 null
signaling receptor activity GO Molecular Function Annotations 2015 1.0 null
H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.28592
GATA3-24758297-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
STK35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31411
connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052123
WSU-FSCCL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05098
cell part LOCATE Predicted Protein Localization Annotations 1.0 null
LNZ308 CCLE Cell Line Gene Expression Profiles 1.0 1.81911
inorganic ion homeostasis GO Biological Process Annotations 2015 1.0 null
KMS26 CCLE Cell Line Gene CNV Profiles -1.0 -2.28392
DACH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.25179
UBE3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27857
H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
HUNS1 CCLE Cell Line Gene Expression Profiles 1.0 1.47145
regulation of lipase activity GO Biological Process Annotations 2015 1.0 null
KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15664
CRCGN016_MCF10A.WT.HP_24H:O21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.09982
COLO-741 GDSC Cell Line Gene Expression Profiles -1.0 -1.61273
neuroactive ligand receptor interaction KEGG Pathways 1.0 null
H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
ZNF652 ChEA Transcription Factor Targets 1.0 null
CTCF_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.10001
regulation of inositol phosphate biosynthetic process GO Biological Process Annotations 2023 1.0 null
MDAMB361 DepMap CRISPR Gene Dependency 1.0 4.24345
Prestwick-864-4113 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
G alpha (q) signalling events Reactome Pathways 2014 1.0 null
gramine-2799 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
BDCA4+_DentriticCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.68119
required GeneRIF Biological Term Annotations 1.0 null
BRD-K52136059 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80377
Vagus nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.483
Lung adenocarcinoma_LUAD_TCGA-44-3396-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Perisynaptic extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.721
SUZ12-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455
PRR36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80395
Adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091
RAB3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58543
Artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.607
sulfaguanidine-4839 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
positive regulation of phospholipase A2 activity GO Biological Process Annotations 2023 1.0 null
METTL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5937
forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.913507
SEMA4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35997
Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.038
Corticotroph adenoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.338
CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null
MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2658
TLCD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41366
SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.981607
implicate GeneRIF Biological Term Annotations 1.0 null
cterminal GeneRIF Biological Term Annotations 1.0 null
DPY30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28789
AFF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46554
dipyridamole-1934 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
GSE232564,GSE232566_0_v_2_nsd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null
hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.768612
TMEM97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.002
schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.258417
transport across blood-brain barrier GO Biological Process Annotations 2023 1.0 null
meclozine-5607 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Organum vasculosum laminae terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.396
BRD-K53770426 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00248
viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.852948
vascular transport GO Biological Process Annotations 2023 1.0 null
GULP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25546
BRD-K40474424 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33053
BRD-K15343038 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20338
Hippocampal pyramidal layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.754
SIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40425
THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960218
ZFP42 ChEA Transcription Factor Targets 1.0 null
PMC3877719__F1 PFOCR Pathway Figure Associations 2024 1.0 null
MDAMB415 DepMap CRISPR Gene Dependency 1.0 2.82943
YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45021
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_767_mouse_Skin - 1 Day GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
ACER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17821
SNU1272 CCLE Cell Line Gene Expression Profiles -1.0 -1.55973
Lung cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
endocrine organ benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.611229
NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75638
UACA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15976
ALKBH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60795
dms79 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.846
D(CH2)5[TYR(ME)2,THR4]OVT DGIdb Drug Targets 2026 1.0 0.420095
PUS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83635
CLCN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71111
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null
synapse part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.074236
H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
LVP DGIdb Drug Targets 2026 1.0 0.84019
organ system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.450324
Pituitary gland cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.495
FLOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29663
SP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78782
single-organism process GO Biological Process Annotations 2015 1.0 null
BRD-K47511177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10597
Hypoglycemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.624
BRD-K11054980 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4986
H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Adrenal medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.388
PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534
H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05148
GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null
ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.3848
Cholestasis CTD Gene-Disease Associations 1.0 1.28333
etiology GeneRIF Biological Term Annotations 1.0 null
H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
integral component of membrane GO Cellular Component Annotations 2015 1.0 null
ZNF530 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 90.0438
Class A/1 (Rhodopsin-like receptors) Reactome Pathways 2014 1.0 null
CRCGN015_HEPG2_48H:J24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.13988
H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
CSNK2A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86025
BRD-K49313348 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01622
CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SEPTIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51326
CRCGN015_MCF10A_48H:G18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.86991
NOSIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58368
Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
Metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.583
PRKCA Hub Proteins Protein-Protein Interactions 1.0 null
GSE109285_3_v_4_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null
Metencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
CRO-AP2 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899
PAX9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17143
regulation of multicellular organismal process GO Biological Process Annotations 2015 1.0 null
BRD-K11631946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28015
Hindbrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
Psychosexual disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.134
metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.46262
cytoplasmic membrane-bounded vesicle LOCATE Curated Protein Localization Annotations 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5152-01A-02R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Subiculum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.108
enzyme binding GO Molecular Function Annotations 2015 1.0 null
positive regulation of vasoconstriction GO Biological Process Annotations 2023 1.0 null
ALDH7A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01295
Ventral striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.175
DMPK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19993
PHF21A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34042
YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45021
abdomen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06907
H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Vas deferens ampulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.855
ENKD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10065
Hairy cell leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.732
E2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.2019
CTCF_GM12875_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33644
20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null
PFDN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 6.27682
BRD-K10435664 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.19656
Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.454
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5173-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8489-01A-31R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
MOLP2 CCLE Cell Line Gene CNV Profiles -1.0 -1.41215
HS870T CCLE Cell Line Gene Expression Profiles 1.0 1.71494
AVT Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
colchicine-644 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
TCEA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37284
Habenular trigone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.687
RCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.47132
positive regulation of inositol phosphate biosynthetic process GO Biological Process Annotations 2025 1.0 null
regulation of phospholipase A2 activity GO Biological Process Annotations 2023 1.0 null
Cingulate gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.383
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
acromegaly DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.183248
GSTP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87093
PMC3500769-srep00875-s3.xls-FOXA1-Time_1_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null
20161705-Table2 GeneSigDB Published Gene Signatures 1.0 null
L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882059
decreased pituitary hormone level MPO Gene-Phenotype Associations 1.0 null
BRD-K44622259 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23516
ZNF446 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6404
LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07756
Necrosis CTD Gene-Disease Associations 1.0 1.50852
TC32 CCLE Cell Line Gene CNV Profiles 1.0 1.42378
HEATR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03876
HNF4alpha_KO_GDS1915_173_mouse_Small intestine GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.916
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6478-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X2-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
ARGIPRESSIN TANNATE DGIdb Drug Targets 2026 1.0 0.420095
H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
FDX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51647
ZIC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44636
PTP4A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81906
LN-405 GDSC Cell Line Gene Expression Profiles -1.0 -1.41894
intramuscular adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33965
FAM91A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63405
d[D-Pal2]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
BRD-K04513994 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02721
GSE164494_1_v_2_rab22a_mouse RummaGEO Gene Perturbation Signatures -1.0 null
FAM234B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13901
Disease Reactome Pathways 2024 1.0 null
NCIH838 CCLE Cell Line Gene Expression Profiles -1.0 -2.58887
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4643-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
OSBPL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.708
APEH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41587
TNK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17189
HEXD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26687
RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64931
CRCGN014_HEPG2_24H:H13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.04552
RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.93699
DAPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43076
paraventricular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.13147
HMEL CCLE Cell Line Gene Expression Profiles 1.0 2.59082
CRCGN014_HEPG2_3H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.2
CTCF_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CRCGN015_HEPG2_48H:G19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.0679
abnormal homeostasis MPO Gene-Phenotype Associations 1.0 null
EBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75615
H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K51398207 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59566
CRCGN016_MCF10A.TP53.M_24H:L10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.80634
BRD-K63547380 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53042
MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67238
GSE140651,GSE140653_2_v_7_med1_human RummaGEO Gene Perturbation Signatures -1.0 null
BRD-K08427390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1673
flumequine-2276 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
neurohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.569622
epididymis HPA Tissue Protein Expression Profiles -1.0 -1.90005
H3K9ac_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
QPCT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41321
HCC1897 CCLE Cell Line Gene Expression Profiles 1.0 1.50159
OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01037
H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
BRD-A98714080 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07239
GSE234340_3_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null
PTPN1_KD_GSE54157_673_human_KM-H2 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
positive regulation of MAPK cascade GO Biological Process Annotations 2023 1.0 null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null
PHOX2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24729
PARP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56103
regulation of blood pressure GO Biological Process Annotations 2015 1.0 null
biological regulation GO Biological Process Annotations 2015 1.0 null
HUPT4 CCLE Cell Line Gene CNV Profiles -1.0 -1.77716
PU1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KB-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
SELENON CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60743
RAB6C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38291
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CRCGN009_HEPG2_24H:D07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.03797
[Phaa1 D-Tyr(Et)2 Val4 Lys6 Tyr-NH28 des-Gly9]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
positive regulation of phospholipase A2 activity GO Biological Process Annotations 2025 1.0 null
FUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90987
H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
HNF4A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CEP20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04624
Pituitary cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.523
UBXN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63879
H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69444
naringin-3286 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
PMC4747358__F3 PFOCR Pathway Figure Associations 2024 1.0 null
PEX26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63376
Frontal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.892
CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GSE163240_2_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null
BRD-K67390061 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04752
Ovarian fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.998
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
MAP2K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18392
POLR2M CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70054
hsa-miR-654-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816
H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
OVMANA DepMap CRISPR Gene Dependency 1.0 5.78167
hippocampus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.71583
ZNF710 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7631
Infertility, Female CTD Gene-Disease Associations 1.0 1.18259
BRD-K57042334 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34432
Venom sac TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.89
MSGN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76718
BRD-K96154586 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3897
RTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21441
H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.2531
positive regulation of inositol phosphate biosynthetic process GO Biological Process Annotations 2023 1.0 null
H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
thalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.03258
embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.06581
corticotropic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.77781
UBAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89016
SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
estradiol_homo sapiens_gpl91_eralpha_gds884 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
BRD-K96101240 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13655
CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null
sample GeneRIF Biological Term Annotations 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
NB13 DepMap CRISPR Gene Dependency 1.0 4.57883
CH157MN CCLE Cell Line Gene Expression Profiles 1.0 2.01669
CRCGN015_MCF10A_48H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.5788
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-CLOSEST_GENE_RUNX3 Rummagene Transcription Factor Associations 2026 1.0 null
WM88 CCLE Cell Line Gene CNV Profiles 1.0 1.34482
Depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.397
EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.878565
BRD-A37523642 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.98961
AMOT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68714
SEC14L5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83054
SNAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1185
female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052635
Pituitary gland benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.926
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null
disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041032
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5377-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K96925976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03731
ZNF483 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16355
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR Rummagene Transcription Factor Associations 2026 1.0 null
CWF19L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06342
ATF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77652
Anterior olfactory nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.098
OCI-AML3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960218
autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.892538
H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R0-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
motif GeneRIF Biological Term Annotations 1.0 null
H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null
H4C16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.93741
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Attention deficit hyperactivity disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.222
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
COLO775 CCLE Cell Line Gene Expression Profiles -1.0 -1.59091
BRD-K22435870 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.86148
CRCGN015_HEPG2_48H:K10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.21462
GNPNAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14977
NO10 DepMap CRISPR Gene Dependency 1.0 4.38203
H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
Pancreatic alpha cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.406
CRCGN015_MCF10A.WT.HP_24H:M16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.551
BRD-K94506829 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14275
Adrenal gland hyperfunction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.148
Visceral hump TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.629
BRD-K88080911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08529
regulation of phospholipase A2 activity GO Biological Process Annotations 2025 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
ZNF33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01079
BRD-K75703503 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08656
Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.044
Arcuate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.915
ISL1-27105846-CHIP-SEQ-CPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
hsa-miR-4692 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347
small cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.308118
BRD-K09863466 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17476
TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.715
GSE234340_4_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null
PMC3470785-NIHMS377161-supplement-3.pdf-463-GLIS3_GLIS3 Rummagene Transcription Factor Associations 2026 1.0 null
H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Mitral cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.112
LINGO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02378
20460173-ImmPortCytokineReceptors GeneSigDB Published Gene Signatures 1.0 null
POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Apical dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.998
GPCR ligand binding Reactome Pathways 2024 1.0 null
LN18 BioGPS Cell Line Gene Expression Profiles 1.0 0.825212
EZH2 ENCODE Transcription Factor Targets 1.0 null
BRD-K60948317 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.63375
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K07697589 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25005
abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.056792
H2BC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08968
BRD-K96295480 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33096
Olfactory lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.677
Disease Reactome Pathways 2014 1.0 null
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
SCAF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24783
BRD-K67862892 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67432
lung TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
BRD-K07826724 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04448
HPAC CCLE Cell Line Gene Expression Profiles -1.0 -1.87479
ZKSCAN3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.7381
H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
valproic acid_homo sapiens_gpl96_gds1050 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Brain stem TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
DLX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98905
regulation of systemic arterial blood pressure GO Biological Process Annotations 2015 1.0 null
ciclosporin-602 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
decreased adrenocorticotropin level MPO Gene-Phenotype Associations 1.0 null
clofilium tosylate-6830 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
autism GAD Gene-Disease Associations 1.0 null
PF-00562151-00-6863 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
ABCD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73351
JM1 CCLE Cell Line Gene CNV Profiles 1.0 1.37523
Asperger syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.307
H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
Hippocampus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.07
positive regulation of phosphate metabolic process GO Biological Process Annotations 2025 1.0 null
Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.144
23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null
NANOG-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.683493
C1orf198 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82549
embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054774
showed GeneRIF Biological Term Annotations 1.0 null
organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.232744
H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
imatinib-483 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
SAP30 ENCODE Transcription Factor Targets 1.0 null
PKBalpha_KO_GDS1784_197_mouse_Embryonic fibroblasts (MEFs) - 48h GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
ARX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24474
Pyramidal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.754
ovary HPA Tissue Protein Expression Profiles -1.0 -1.90005
LAMC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21161
SC-58125-507 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
d[Leu4 Dap8]VP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.185
POMGNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91306
H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
Prolactinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.413
RBAK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67965
Perineuronal net TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.666
H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null
G alpha (q) signalling events Reactome Pathways 2024 1.0 null
BRD-K05417183 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32857
REH GDSC Cell Line Gene Expression Profiles 1.0 1.61528
H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
relcovaptan Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
abnormal lipid level MPO Gene-Phenotype Associations 1.0 null
thorax TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056183
CTCF_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
decreased circulating pituitary hormone level MPO Gene-Phenotype Associations 1.0 null
CYB5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57733
dlx4_00000000_mcfdash7_gof_human_gpl201_gse21657 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.295022
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SR-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
lung cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
Perturb_13919_KD_TARDBP_SRP295809 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.671
ZNF529 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3817
abnormal aggression-related behavior MPO Gene-Phenotype Associations 1.0 null
DLX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73129
BRD-K14671808 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00509
8-MG-BA GDSC Cell Line Gene Expression Profiles 1.0 2.33979
BRD-K24205443 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25654
carbohydrate metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.080018
[3H]d[Cha4]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Reactome Pathways 2014 1.0 null
Cul2-RING ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.587
abnormal circulating corticosterone level MPO Gene-Phenotype Associations 1.0 null
BRD-K10325583 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03185
H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CRCGN015_MCF10A.TP53.M_24H:K11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.32825
regulation of inositol phosphate biosynthetic process GO Biological Process Annotations 2025 1.0 null
chemical homeostasis GO Biological Process Annotations 2015 1.0 null
cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K73969016 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00606
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null
nucleus lentiformis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.263327
H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K27me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K30038014 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60723
Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.8712
G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null
Basophil adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.144
EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
WHSC1 ENCODE Transcription Factor Targets 1.0 null
ADRA2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34595
BRD-K68746558 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26431
S100A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42539
CBX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55518
YPEL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89388
FES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93831
NKX2-3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80208
NIPBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70421
abnormal circulating pituitary hormone level MPO Gene-Phenotype Associations 1.0 null
SLC38A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31017
496100407_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.64104
Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.804
endosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Medulla oblongata TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.364
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
SIN3A ENCODE Transcription Factor Targets 1.0 null
POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
SCAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5748
OTUD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3895
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6032-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
ROS50 DepMap CRISPR Gene Dependency 1.0 3.99918
BRD-K28357534 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25393
Perturb_14340_OE_CTCFL_SRP306444 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.41108
activation of phospholipase c activity GO Biological Process Annotations 2015 1.0 null
Lung adenocarcinoma_LUAD_TCGA-05-4249-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
HGH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41911
levamisole-1410 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
GSE164494_0_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null
496100366_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40155
membrane-bounded vesicle LOCATE Curated Protein Localization Annotations 1.0 null
RASSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17322
Edema CTD Gene-Disease Associations 1.0 1.29164
RETREG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51505
abnormal behavioral response to xenobiotic MPO Gene-Phenotype Associations 1.0 null
H3K27me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
RARB-24833708-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
SPARC_Deficiency_GDS3636_524_mouse_Lens epithelium GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
homeostasis/metabolism phenotype MPO Gene-Phenotype Associations 1.0 null
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
GSE100316_5_v_4_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null
H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
CREBZF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65516
FABP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90457
cytoplasmic part LOCATE Curated Protein Localization Annotations 1.0 null
hsa-miR-3922-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663
BEND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79365
H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
abnormal behavior MPO Gene-Phenotype Associations 1.0 null
BRD-K97657359 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38367
BRD-K23342427 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29201
H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null
BRD-K16698502 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06745
PRKCG MSigDB Cancer Gene Co-expression Modules 1.0 null
Subfornical organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.514
intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null
bleomycin-sulfate LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00205
benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.237706
Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Desmopressin DrugBank Drug Targets 1.0 null
CRCGN015_HEPG2_48H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.40528
CRCGN015_MCF10A.TP53.M_24H:I07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.27445
CCNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71157
BRD-A75087829 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05941
[VAL4]AVP DGIdb Drug Targets 2026 1.0 0.420095
ZNF677 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.42741
depressive disorder, major GAD Gene-Disease Associations 1.0 null
OVCAR4 CCLE Cell Line Gene CNV Profiles -1.0 -1.42766
CRCGN015_HEPG2_48H:L19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -3.09173
H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
regulation of metabolic process GO Biological Process Annotations 2015 1.0 null
Vasopressin V1B receptor InterPro Predicted Protein Domain Annotations 1.0 null
H3K4me1_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Hyperpituitarism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.447
NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15296
MAX ENCODE Transcription Factor Targets 1.0 null
BRD-K32511780 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1863
Suicidal DisGeNET Gene-Disease Associations 1.0 null
POLR1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81553
H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
Anterior cingulate cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.349
ETS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0935
nucleotide-excision repair factor 4 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.753
olfactory lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.507064
RNF149 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5899
496100503_HIP_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.45835
496100465_HIP_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.25837
Chromosomal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.218
PATZ1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 155.392
abnormal testosterone level MPO Gene-Phenotype Associations 1.0 null
BRD-K12347309 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08779
Hypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.696
positive regulation of lipase activity GO Biological Process Annotations 2015 1.0 null
Ischemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.109
BRD-K45576113 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21891
CRCGN014_HEPG2_3H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.1527
prefrontal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.247719
d(CH2)5[Tyr(Me)2 Thr4]OVT Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
BRD-K89820077 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08814
GPX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4158
UBTFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22889
H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
LMF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26779
PRELID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08686
excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.337072
SRY ChEA Transcription Factor Targets 1.0 null
Serotonergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.955
BCL6-25482012-CML-JURL-MK1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4477
PPARGC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55353
BRD-K54554531 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03802
Anxiety DisGeNET Gene-Disease Associations 1.0 null
hyperpituitarism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.136429
CCDC24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4798
UWB1_289 COSMIC Cell Line Gene Mutation Profiles 1.0 null
Olfactory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.273
H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null
FNDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99893
CTCF_GM12864_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
LDAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73481
H3K27me3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960218
GSE147893,GSE147897_2_v_1_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null
Venom duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.758
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.237009
PARP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68379
GATA6-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.258
SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9099
Perineuronal net COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.725
Nervous System Diseases CTD Gene-Disease Associations 1.0 1.26267
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null
biological_process GO Biological Process Annotations 2015 1.0 null
496100459_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.4069
hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.432608
molecular_function GO Molecular Function Annotations 2015 1.0 null
kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050288
MOZAVAPTAN DGIdb Drug Targets 2026 1.0 0.84019
RNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68672
NUMBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33373
CRCGN017_MCF10A.WT.HP_24H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.88905
ZNF415 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93936
LITAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78608
SOX11-23321250-Z138-A519-JVM2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null
ANKIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07576
CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Carotid body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.879
cellular cation homeostasis GO Biological Process Annotations 2015 1.0 null
tn5b14 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.824
NELFE ENCODE Transcription Factor Targets 1.0 null
MS751 COSMIC Cell Line Gene Mutation Profiles 1.0 null
adrenal gland GTEx Tissue Gene Expression Profiles -1.0 -0.942714
COLO-800 COSMIC Cell Line Gene Mutation Profiles 1.0 null
CRX-20693478-RETINA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
COX7A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16021
TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1042
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4634-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.733
KBTBD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23411
Pregnancy Complications CTD Gene-Disease Associations 1.0 1.04051
ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8233
GABRD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48147
KP-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null
chlormezanone-1620 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
flufenamic acid-5478 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
F8A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52433
EEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67512
cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342
ZNF273 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71292
SNU719 CCLE Cell Line Gene Expression Profiles -1.0 -1.6467
TrigeminalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603
CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
F5 CCLE Cell Line Gene Expression Profiles 1.0 2.2529
BTBD18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71501
NANOS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.56682
L-type voltage-gated calcium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.508
RS11846 BioGPS Cell Line Gene Expression Profiles -1.0 -1.19192
LN18 DepMap CRISPR Gene Dependency 1.0 4.17356
ZBTB7A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8897
Peptide GPCRs WikiPathways Pathways 2024 1.0 null
regulation of molecular function GO Biological Process Annotations 2015 1.0 null
Colorectal Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null
ELF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2808
ZKSCAN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19318
Vasopressin DrugBank Drug Targets 1.0 null
Depressive Disorder, Major HuGE Navigator Gene-Phenotype Associations 1.0 null
Brain Lower Grade Glioma_LGG_TCGA-RY-A840-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
RBPJ-21746931-IB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
COVID-19 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.423
DU4475 DepMap CRISPR Gene Dependency 1.0 6.78714
Avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.314
AGS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960218
piribedil-5434 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
extracellular region part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047599
CRCGN014_HEPG2_24H:A20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.49811
MGST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5133
autistic GeneRIF Biological Term Annotations 1.0 null
IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 1.76932
GSE67266_7_v_3_etoposide_mouse RummaGEO Drug Perturbation Signatures -1.0 null
ZNF671 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42833
H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null
NCIH1915 DepMap CRISPR Gene Dependency 1.0 2.94785
Lateral entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.882
BRD-K33221810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05372
Depressive Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null
IFT25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16903
HCC827GR5 CCLE Cell Line Gene Expression Profiles 1.0 2.8906
Panic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.99
H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
TEAD4 ENCODE Transcription Factor Targets 1.0 null
TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201
Malpighian tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.517
CHD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41985
CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
MYCL MSigDB Cancer Gene Co-expression Modules 1.0 null
H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
CYP2U1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93323
CRCGN015_MCF10A.TP53.M_24H:A22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.1475
NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48013
OH-LVA DGIdb Drug Targets 2026 1.0 0.420095
TSH producing pituitary tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.265
SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847497
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
vasopressin receptor activity GO Molecular Function Annotations 2015 1.0 null
H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Diagonal band TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.532
CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
positive regulation of multicellular organismal process GO Biological Process Annotations 2023 1.0 null
huh-7 BioGPS Cell Line Gene Expression Profiles 1.0 1.34341
NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07867
decreased circulating adrenocorticotropin level MPO Gene-Phenotype Associations 1.0 null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
PAX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86071
BRD-A89354030 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15986
H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
ZNF488 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80461
ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8024
SNU886 CCLE Cell Line Gene Expression Profiles -1.0 -1.8414
cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null
NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GSE239844_8_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null
TUHR10TKB DepMap CRISPR Gene Dependency 1.0 3.76115
GSE112202_5_v_2_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null
Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
regulation of blood circulation GO Biological Process Annotations 2015 1.0 null
GMPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84609
STYX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78211
Breast - Mammary Tissue GTEx Tissue Gene Expression Profiles 2023 1.0 7.1721
Pain CTD Gene-Disease Associations 1.0 1.19477
eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SOX6-21985497-MYOTUBES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
adrenal gland HPA Tissue Protein Expression Profiles 1.0 2.76329
PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.883017
H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
DOR 13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948179
Metabolic disorders of biological oxidation enzymes Reactome Pathways 2014 1.0 null
Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091
HOXD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61483
LP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00651
nose TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.181177
H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PMC7495487-41598_2020_71030_MOESM2_ESM.xlsx-Sheet1-NR1A1_THRA Rummagene Transcription Factor Associations 2026 1.0 null
H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
FOXD4L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.30813
KLM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.48098
ITPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34052
H3K4me1_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
JHH7 DepMap CRISPR Gene Dependency 1.0 2.2565
aggression GeneRIF Biological Term Annotations 1.0 null
H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
UBXN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06424
NCI-H1436 COSMIC Cell Line Gene Mutation Profiles 1.0 null
H3K27me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CRCGN012_HEPG2_24H:L03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.6731
CTCF_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.429
HMGN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70559
Bipolar Disorder DisGeNET Gene-Disease Associations 1.0 null
ZNF503 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98105
abnormality of higher mental function GWASdb SNP-Phenotype Associations 1.0 0.245175
SV2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83334
CRCGN015_HEPG2_48H:I06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.1904
LB771-HNC GDSC Cell Line Gene Expression Profiles -1.0 -1.478
REST_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GLI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2271
abnormal emotion/affect behavior MPO Gene-Phenotype Associations 1.0 null
HT55 COSMIC Cell Line Gene Mutation Profiles 1.0 null
SW403 DepMap CRISPR Gene Dependency 1.0 6.11429
H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.492
cytosolic calcium ion homeostasis GO Biological Process Annotations 2015 1.0 null
WFIKKN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52593
PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947113
Signaling by GPCR Reactome Pathways 2024 1.0 null
Anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.324
Neuroendocrine tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.071
CCN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04704
Adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.575
496100511_TCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.97547
Prestwick-691-4172 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Peptide GPCRs(Mus musculus) WikiPathways Pathways 2014 1.0 null
HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null
CNBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10236
alvespimycin-6973 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Prostate adenocarcinoma_PRAD_TCGA-HC-7821-01A-12R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null
EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
[Phaa1 D-Tyr(Et)2 Lys6 des-Gly9]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
CRCGN012_HEPG2_24H:D09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.36945
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_to_Fay_Heat_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null
ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null
hsa-miR-541 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544
GJC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3878
PHA granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.503
PHF8 ENCODE Transcription Factor Targets 1.0 null
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CDX2-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
SLC25A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67744
SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
STC-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.843
Gli2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.9659
H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
posterior lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.221521
CD105+_Endothelial BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.18729
SH2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55
LHX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35944
H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null
H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
MATCAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5208
neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068702
CAPN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5531
NCI H226 BioGPS Cell Line Gene Expression Profiles -1.0 -1.12929
peptide receptor activity GO Molecular Function Annotations 2015 1.0 null
TCEAL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00343
GSE103309_2_v_0_ube3a_human RummaGEO Gene Perturbation Signatures -1.0 null
[3H]NELIVAPTAN DGIdb Drug Targets 2026 1.0 1.26029
BRD-A07214340 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28482
496100355_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.01995
KLHL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33318
NCI-H1435 COSMIC Cell Line Gene Mutation Profiles 1.0 null
DDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86265
FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null
CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Sexual health disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.115
GSE152441,GSE152442_1_v_4_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null
Pituitary-Dependent Cushing'S Disease DisGeNET Gene-Disease Associations 1.0 null
Mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.43
CP66-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null
H3K27ac_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
ZNF416 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71222
GSE157911_1_v_0_hnf4a_mouse RummaGEO Gene Perturbation Signatures 1.0 null
KIAA0753 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38255
Cardiac Arrest DisGeNET Gene-Disease Associations 1.0 null
Juxtaglomerular apparatus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.049
PSEN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88989
CHD1 ENCODE Transcription Factor Targets 1.0 null
[3H]SSR149415 Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4162-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
SUPT3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92286
IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null
REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Asperger Syndrome HuGE Navigator Gene-Phenotype Associations 1.0 null
CD74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36201
H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Paraventricular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.523
H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
lung HPA Tissue Protein Expression Profiles -1.0 -1.11106
496100460_TCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.51381
CRCGN016_MCF10A.TP53.M_24H:H10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.7
C32 CCLE Cell Line Gene CNV Profiles 1.0 2.27167
RIMKLA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73607
piriform area TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.558856
hsa-miR-4514 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135
SRY-22984422-TESTIS-RAT ChEA Transcription Factor Targets 2022 1.0 null
CRCGN017_MCF10A.TP53.M_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.1917
phenformin-21 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null
GSE123372,GSE123373_1_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null
positive regulation of phospholipase activity GO Biological Process Annotations 2025 1.0 null
U0125-663 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
abnormal circulating lipid level MPO Gene-Phenotype Associations 1.0 null
Perturb_2985_KO_KMT2C_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.97872
Cerebral gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.385
BRD-K60554389 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23626
FOXO1-25302145-T-LYMPHOCYTE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7847
H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Alexithymia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04
NFKBIZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55685
Activin B complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.56
intrinsic component of plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
POR_KO_GDS1678_760_mouse_Colon GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
CRCGN015_MCF10A.WT.HP_24H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0698
FNDC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83312
response to hormone GO Biological Process Annotations 2015 1.0 null
CRCGN017_MCF10A.WT.HP_24H:E07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.4106
regulation of arachidonic acid secretion GO Biological Process Annotations 2023 1.0 null
positive regulation of metabolic process GO Biological Process Annotations 2015 1.0 null
BRD-K27302831 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0906
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null
AtT-20 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.608
CRCGN016_MCF10A.TP53.M_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.7728
MICAL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.03298
G protein-coupled receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.218
olfactory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.06515
H2AC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12369
POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GPCRs, Class A Rhodopsin-like(Mus musculus) WikiPathways Pathways 2014 1.0 null
CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Congestive heart failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27
BRD-K39908587 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06791
CUX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13647
Cervical ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.52
NDFIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8045
particularly GeneRIF Biological Term Annotations 1.0 null
Corpus albicans TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.605
H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Inner medullary collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.915
FZD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77944
Generalized anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.693
POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
positive regulation of multicellular organismal process GO Biological Process Annotations 2015 1.0 null
INAVA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80292
C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.14239
hsa-miR-4300 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397
JUN_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.09
496100576_HIP_dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.78536
DDX19B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27055
CTCF_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null
CSNK1G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56305
H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Kidney Diseases CTD Gene-Disease Associations 1.0 1.42401
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
H3K27me3_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Rostral ventrolateral medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.329
Acetamides CTD Gene-Chemical Interactions 1.0 null
doxorubicin_homo sapiens_gpl6947_gse25741 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
BRD-K31330911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20539
H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
PMC3500769-srep00875-s3.xls-CEBP-Time_1_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null
CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
CTCF_GM12865_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
major GeneRIF Biological Term Annotations 1.0 null
CRCGN012_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.52015
ATG2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36048
animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01375
BRD-K53931904 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.74609
TNKS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53593
disorders GeneRIF Biological Term Annotations 1.0 null
UBB_KO_GDS3906_492_mouse_Testis - 14 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0625
ZNF384 ENCODE Transcription Factor Targets 1.0 null
LRP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92531
CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K27me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SNX22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2694
CRCGN017_MCF10A.WT.HP_24H:A21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.14715
CDC42EP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69695
H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
HNF4A ChEA Transcription Factor Targets 1.0 null
TO14 DepMap CRISPR Gene Dependency 1.0 3.00941
Non-odorant GPCRs(Mus musculus) WikiPathways Pathways 2014 1.0 null
NFE2-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
abamectin-7218 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Mitochondrial creatine kinase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.612
membrane LOCATE Predicted Protein Localization Annotations 1.0 null
PREPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44561
H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
GPCRs class A rhodopsin like WikiPathways Pathways 2024 1.0 null
respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.215992
H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
chloramphenicol-5466 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
PRDM9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 367.148
Herring body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.525
decreased circulating corticosterone level MPO Gene-Phenotype Associations 1.0 null
CRCGN008_HEPG2_24H:H02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.32815
H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null
positive regulation of molecular function GO Biological Process Annotations 2015 1.0 null
ERF::NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.2166
organelle GO Cellular Component Annotations 2015 1.0 null
MAFK ENCODE Transcription Factor Targets 1.0 null
H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.3747
Lung adenocarcinoma_LUAD_TCGA-44-2666-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null
GSE190316,GSE190324_6_v_11_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null
NEIL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8532
NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09728
ETS1 ENCODE Transcription Factor Targets 1.0 null
PMC3500769-srep00875-s3.xls-AP1-Time_1_JUN Rummagene Transcription Factor Associations 2026 1.0 null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K32516224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39515
HK2 CCLE Cell Line Gene Expression Profiles 1.0 2.48842
BRD-K76537832 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06464
Liver Diseases CTD Gene-Disease Associations 1.0 1.28672
cushing's syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.08999
CRCGN015_MCF10A.WT.HP_24H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.89708
BRD-K52339742 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05865
SNUC5 CCLE Cell Line Gene Expression Profiles -1.0 -1.86627
SPATA33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.65692
H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
CJM DepMap CRISPR Gene Dependency 1.0 3.95308
PRRT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03932
CRCGN014_HEPG2_3H:E07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.12705
BRD-K17133642 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55707
[tBaa1 D-Tyr(Et)2 Val4 Lys6 Arg-NH28 des-Gly9]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A770-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K29298614 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46623
CRCGN012_HEPG2_24H:G04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.0279
abnormal nervous system physiology MPO Gene-Phenotype Associations 1.0 null
pyramidal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.335233
celecoxib-482 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
BRD-K41790019 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15209
BRD-K45138525 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47122
CRCGN013_HEPG2_24H:I15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.72636
ONCODG1 CCLE Cell Line Gene CNV Profiles 1.0 1.36254
FEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47126
UBXN11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41911
CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Lung adenocarcinoma_LUAD_TCGA-69-7974-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
KIF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09943
[Phaa1 D-Tyr(Me)2 Arg6 Tyr-NH29]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Periglomerular cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.05
Stinger TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.752
H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
RKN CCLE Cell Line Gene CNV Profiles -1.0 -2.59447
Vasopressin-like receptors Reactome Pathways 2024 1.0 null
brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
DCTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02584
membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.243158
positive regulation of icosanoid secretion GO Biological Process Annotations 2023 1.0 null
Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178
EZH2-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.6281
quinethazone-4351 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
NFKB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4554
Pontine nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.674
BRD-K08389897 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13462
Internal plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.716
substance-related disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.716
NABP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05339
Plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0
H3K27me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
BFTC-905 COSMIC Cell Line Gene Mutation Profiles 1.0 null
Terlipressin DrugBank Drug Targets 1.0 null
streptozocin-6098 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
TMEM184A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27959
HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7473
adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.110145
H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K46619710 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22656
nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.94095
olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.509027
SFXN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78337
NABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53071
BRD-K80564983 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03827
empathy GeneRIF Biological Term Annotations 1.0 null
increased circulating testosterone level MPO Gene-Phenotype Associations 1.0 null
NR2E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15938
CRCGN014_HEPG2_3H:K20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.4107
recurrent GeneRIF Biological Term Annotations 1.0 null
Mental Depression DisGeNET Gene-Disease Associations 1.0 null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null
Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.663
Anterior hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.509
CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
DPH5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73922
BRD-K89515752 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20923
H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
BRD-K06181307 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24927
Ovariole TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.657
ST14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59268
Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.668
Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.3792
SLC29A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52274
ERGIC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62216
Hepatic Encephalopathy CTD Gene-Disease Associations 1.0 1.10317
OCT4-21477851-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
GB2 DepMap CRISPR Gene Dependency 1.0 2.37073
synapse-associated extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.72
HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null
single-organism cellular process GO Biological Process Annotations 2015 1.0 null
Bipolar Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null
DPP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.322
Depressive Disorder CTD Gene-Disease Associations 1.0 1.11639
BRD-K28995832 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2829
Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.755
BRD-K50053371 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42174
Pituicyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.359
lynestrenol-1953 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
avp GeneRIF Biological Term Annotations 1.0 null
perphenazine-1956 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
frontal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.535833
system process GO Biological Process Annotations 2015 1.0 null
H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
positive regulation of alcohol biosynthetic process GO Biological Process Annotations 2023 1.0 null
Major depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.205
cell part LOCATE Curated Protein Localization Annotations 1.0 null
BLMH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68621
ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44822
d(CH2)5[D-Ile2 Ile4 Ala-NH29]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
CDX2-21402776-INTESTINAL-VILLUS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
ZSCAN26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10153
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1 Rummagene Transcription Factor Associations 2026 1.0 null
H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
regulation of hydrolase activity GO Biological Process Annotations 2015 1.0 null
H3K27me3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
ZNF563 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87242
MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SHLD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24847
control GeneRIF Biological Term Annotations 1.0 null
Pain agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.511
OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null
OH-LVA Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
LB2518-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null
salicyl-alcohol LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35632
Prostate gland smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.104
BRD-K53104784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39092
BRD-K42732309 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75557
CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PAIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69747
PHA-00851261E-4330 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
TAF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79062
calcium ion homeostasis GO Biological Process Annotations 2015 1.0 null
disease GWASdb SNP-Disease Associations 1.0 0.024136
cornu ammonis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.260606
BRD-K02811477 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22011
H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0
BRD-K56776985 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.12886
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null
mecamylamine-hcl LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0326
PIGP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3446
ASCL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03841
ACVR2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91231
Melancholia DisGeNET Gene-Disease Associations 1.0 null
Renal medulla cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.521
H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7676
positive regulation of arachidonate secretion GO Biological Process Annotations 2025 1.0 null
integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
MED24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95572
H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
Signal Transduction Reactome Pathways 2014 1.0 null
MANBAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17159
H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Basal forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.645
GABPA ENCODE Transcription Factor Targets 1.0 null
Unipolar Depression DisGeNET Gene-Disease Associations 1.0 null
PAX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.753
TCAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45263
BRD-K03305572 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0582
ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7442
preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.59606
CAOV3 CCLE Cell Line Gene CNV Profiles -1.0 -1.58209
H3K27me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
NEK8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93589
BRD-K55877261 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97708
acetylcholine-gated channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.261
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SRSF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4571
GSE106170_1_v_0_nap1l3_human RummaGEO Gene Perturbation Signatures 1.0 null
EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GSE48812_8_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
cellular calcium ion homeostasis GO Biological Process Annotations 2015 1.0 null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
KIF20B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52762
BRD-K30812092 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.36421
KIF22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33122
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
PURG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93498
GSS CCLE Cell Line Gene Expression Profiles -1.0 -1.75078
NCIH3255 CCLE Cell Line Gene Expression Profiles -1.0 -2.15467
cinchocaine-1889 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
GSE174751_0_v_1_postn_mouse RummaGEO Gene Perturbation Signatures -1.0 null
BRD-K81293413 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21731
protective GeneRIF Biological Term Annotations 1.0 null
PHOX2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02817
HNF4A ENCODE Transcription Factor Targets 1.0 null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K43390655 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28218
NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.9921
GSE69244_1_v_0_j147_mouse RummaGEO Drug Perturbation Signatures 1.0 null
Hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.642
MPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03693
cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.704764
CKAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06772
WM-266-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835055
CARD19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49425
HOXD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25644
LHX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50468
PLAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7881
Umbilical artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.543
Ventral globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.77
CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Neuroactive ligand-receptor interaction KEGG Pathways 2026 1.0 null
Perturb_6637_KO_SATB1_ERP024525 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0
CTCF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 228.498
FEZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52078
panic GeneRIF Biological Term Annotations 1.0 null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
ANKRD39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58987
fursultiamine-2929 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Thalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.367
d(CH2)5[D-Ile2 Ile4 Ala-NH2]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
Vestibular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.545
organelle LOCATE Curated Protein Localization Annotations 1.0 null
GSE113734_3_v_0_qprt_human RummaGEO Gene Perturbation Signatures -1.0 null
Endosome COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0
regulation of cellular process GO Biological Process Annotations 2015 1.0 null
BICR6 DepMap CRISPR Gene Dependency 1.0 4.25043
KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881966
Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.604
MPZL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71229
kinase binding GO Molecular Function Annotations 2015 1.0 null
Nucleus lentiformis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.604
Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0
BRD-K42671261 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44273
H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Area postrema TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.155
TRAPPC6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37116
NCIH28 DepMap CRISPR Gene Dependency 1.0 2.90323
BRD-K57244822 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04606
TE-11 GDSC Cell Line Gene Expression Profiles 1.0 1.83381
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Class A/1 (Rhodopsin-like receptors) Reactome Pathways 2024 1.0 null
SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8716
Diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.592
Autistic Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null
SHROOM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86217
KPNSI9S CCLE Cell Line Gene CNV Profiles 1.0 1.60316
Neurosecretory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.325
BT483 CCLE Cell Line Gene CNV Profiles 1.0 1.37036
H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Periventricular nucleus of hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.808
H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
BRD-K47947160 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02495
MATR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7278
FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6463
GSE234340_12_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null
BRD-K76900919 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55211
BRD-K14970242 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08895
Hypopituitarism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.09
Hormone signaling KEGG Pathways 2026 1.0 null
CRCGN015_MCF10A_48H:P04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.32105
blood plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.594451
haplotype GeneRIF Biological Term Annotations 1.0 null
d(CH2)5[Tyr(Me)2 Thr4 Phe(3I 4N3)-NH29]OVT Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
EPLC272H DepMap CRISPR Gene Dependency 1.0 3.46292
CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
ERA-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
DOLPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23042
SOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67865
EFO21 DepMap CRISPR Gene Dependency 1.0 2.09561
Melanotroph TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.735
GSE112714_2_v_0_ctnnb1_human RummaGEO Gene Perturbation Signatures -1.0 null
ALG9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64317
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SX-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
duodenum HPA Tissue Gene Expression Profiles 1.0 0.83135
fulvestrant-5926 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
cerebellum TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
hsa-miR-1825 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992
C12orf4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54344
Perikaryon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.81
KDSR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94234
HNF4A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047169
asperger GeneRIF Biological Term Annotations 1.0 null
CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26401
CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05098
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
TMED3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27661
protein kinase binding GO Molecular Function Annotations 2025 1.0 null
SkeletalMuscle BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.40347
BRD-K08702524 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45094
Benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.384
g/g TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.016
TMEM203 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2204
BRD-K21466747 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38097
Posterior lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.368
SMC3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
1-(5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide CTD Gene-Chemical Interactions 1.0 null
PNCK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68804
CRCGN015_HEPG2_48H:A13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.30128
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Perturb_14389_KD_PAX8_SRP276625 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0
PMC3500769-srep00875-s3.xls-PAX2-Time_1_PAX2 Rummagene Transcription Factor Associations 2026 1.0 null
respiratory system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
ZNF331 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.2463
rofecoxib-463 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
EIF2AK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71722
ZNF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7203
GSE60837_2_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null
BRD-K77875023 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48754
BRD-K34531548 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37449
metencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
GABPA_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GABRQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99516
SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null
TGFBR2_knockout_294_GSE36778 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.61388
cellular response to hormone stimulus GO Biological Process Annotations 2023 1.0 null
BRD-K36324810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55817
Appendix BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.82849
NCIH508 CCLE Cell Line Gene CNV Profiles -1.0 -1.56012
SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.19867
496100526_TCx_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07894
CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Eating disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.146
BRD-K83115435 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17209
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
BRD-K30269093 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07887
MAST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37231
ZNF574 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.9869
Inflammation CTD Gene-Disease Associations 1.0 1.09506
Mogguvw TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.731
hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.45193
PIK3CD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24736
fenbufen-3618 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.67181
diphemanil metilsulfate-1912 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
thioridazine-4164 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
basal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.44181
H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K96839404 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29151
H3K27me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
Cerebral ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.587
Calcium signaling pathway KEGG Pathways 2026 1.0 null
Small Cell Carcinoma Of Lung DisGeNET Gene-Disease Associations 1.0 null
BRD-K89260735 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30629
SNCA_KO_GDS4153_442_mouse_Cerebellum - 6 month GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
BTBD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83057
CRCGN015_MCF10A_48H:J16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.4302
GPATCH11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86556
ZFP64 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50001
SUP-M2 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899
CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0044
ORAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40333
POU6F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18139
CTCF_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Premature ejaculation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.217
Stratum lucidum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.57
YY1 JASPAR Predicted Transcription Factor Targets 1.0 null
BRD-K95951626 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29393
GSE152441,GSE152442_1_v_2_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null
H1-6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17819
BRD-K73442516 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01273
TMEM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2618
FOXE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39085
positive regulation of carbohydrate metabolic process GO Biological Process Annotations 2025 1.0 null
abnormal pituitary hormone level MPO Gene-Phenotype Associations 1.0 null
Sarcoma_SARC_TCGA-HB-A3L4-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5501-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Claustrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.706
MTARC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92453
tretinoin-447 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
HSPB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53726
Medullary collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.834
H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
Locus ceruleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.432
cellular chemical homeostasis GO Biological Process Annotations 2015 1.0 null
Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.6582
Alcoholism HuGE Navigator Gene-Phenotype Associations 1.0 null
reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051008
GTF2F1 ENCODE Transcription Factor Targets 1.0 null
H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
GSE229468,GSE229471_2_v_3_znf587_human RummaGEO Gene Perturbation Signatures 1.0 null
TBP ENCODE Transcription Factor Targets 1.0 null
regulation of systemic arterial blood pressure by hormone GO Biological Process Annotations 2015 1.0 null
Tegmentum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.529
VPS26C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44212
ZNF501 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56112
BRD-K61441533 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.10028
GSE109285_5_v_4_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null
LONP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45774
TEC MSigDB Cancer Gene Co-expression Modules 1.0 null
protein binding GO Molecular Function Annotations 2015 1.0 null
ACTH-independent macronodular adrenal hyperplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.504
H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.92054
CD56+_NKCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.872283
hsa-miR-920 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187
CTNNAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45041
Diabetes insipidus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.421
median nucleus of thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.13014
SUZ12_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30046
BRD-K78712486 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18017
BRD-K33438042 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56257
CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Dentate gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.451
H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
molecular transducer activity GO Molecular Function Annotations 2015 1.0 null
PFKM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78668
ANGPTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34399
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null
C15orf62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87071
soft tissue HPA Tissue Protein Expression Profiles -1.0 -0.761194
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
DIFI DepMap CRISPR Gene Dependency 1.0 2.07033
GSE152441,GSE152442_7_v_2_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null
organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908
PRKCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54357
BRD-K84277608 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07237
glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.083075
P2URK562 DepMap CRISPR Gene Dependency 1.0 5.91205
GSE144231_6_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null
IMCD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.533
BRD-K69152679 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19759
export GeneRIF Biological Term Annotations 1.0 null
Creatine kinase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.563
ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2665
BRD-K63017817 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03342
GSE148692,GSE148695_2_v_0_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null
HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72395
ZNF354C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35692
bipolar GeneRIF Biological Term Annotations 1.0 null
diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.965496
SOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93629
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null
SFMBT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1161
AVP Guide to Pharmacology Protein Ligands of Receptors 1.0 null
PANK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40334
CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Brain ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.092
TPRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42388
CRCGN017_MCF10A.WT.HP_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.11495
COASY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11307
Cerebellum BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.934683
GSE229468,GSE229471_0_v_3_znf587_human RummaGEO Gene Perturbation Signatures 1.0 null
traits GeneRIF Biological Term Annotations 1.0 null
JUN ENCODE Transcription Factor Targets 1.0 null
MYC_KD_GSE22139_685_human_medulloblastoma GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4893-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342
Pituitary gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.955
GALNT12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97123
hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.507064
H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
IVNS1ABP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80791
BRD-K40060703 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12119
H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
ZDHHC22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65323
BRD-K41327620 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22789
Basal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.11
ZNF470 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44205
H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Henles loop TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.745
H3K27me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
TFDP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1206
ZNF536 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21859
positive regulation of vasoconstriction GO Biological Process Annotations 2015 1.0 null
MID1IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.771
vesicle LOCATE Curated Protein Localization Annotations 1.0 null
BRD-K65561930 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00055
GSE152441,GSE152442_1_v_5_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null
TYK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89744
Glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.733
BRD-K80733946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31971
cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.699035
H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Nutrition disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.306
NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01037
H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
P300-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
EAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4327
TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1334
syndrome GeneRIF Biological Term Annotations 1.0 null
LAMA2_Deficiency_GDS1778_747_mouse_Diaphragm (from dystrophia muscularis -dy/dy- mouse model) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null
addison's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.425139
CTCF_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null
NACAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85549
cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.422782
regulation of system process GO Biological Process Annotations 2015 1.0 null
MAPK12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61914
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K20347026 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80875
Peptide ligand-binding receptors Reactome Pathways 2024 1.0 null
GSE120200,GSE127269_1_v_2_asxl1_human RummaGEO Gene Perturbation Signatures 1.0 null
HA1E DepMap CRISPR Gene Dependency 1.0 2.22201
143B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.830107
desmopressin Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
butirosin-666 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
NEUROD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5329
L363 DepMap CRISPR Gene Dependency 1.0 3.39969
CRCGN017_MCF10A.WT.HP_24H:E10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.5512
H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
BRD-K90852412 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21649
PMC5118094__F3 PFOCR Pathway Figure Associations 2023 1.0 null
KLF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8213
Pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.2
cognitive disorder GWASdb SNP-Disease Associations 1.0 0.615118
FBXO33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06775
MYL12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64777
avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.546533
METTL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3098
ST6GALNAC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6251
Zona reticulata TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.805
abnormal corticosterone level MPO Gene-Phenotype Associations 1.0 null
abnormal lipid homeostasis MPO Gene-Phenotype Associations 1.0 null
Catecholaminergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.794
HEK-293-TrkB cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.855
BRD-K75900905 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82592
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Cranial nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.476
HGS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71978
polymorphism GeneRIF Biological Term Annotations 1.0 null
pancreas GeneRIF Biological Term Annotations 1.0 null
pars distalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.2723
PRRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82013
endogenous depression DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.800744
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
ETV6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63449
H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null
GPR143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07136
LPCAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81917
BRD-K95761590 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07293
rt1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.545
NCIH1648 CCLE Cell Line Gene Expression Profiles -1.0 -3.21616
Mammary myoepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.778
TALL-1 GDSC Cell Line Gene Expression Profiles 1.0 1.94473
Adenohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.697
Depression DisGeNET Gene-Disease Associations 1.0 null
abnormal circulating hormone level MPO Gene-Phenotype Associations 1.0 null
Glomerular layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.145
ONECUT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07625
PRDM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49608
all GWASdb SNP-Phenotype Associations 1.0 0.028339
SPACA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04052
DU4475 CCLE Cell Line Gene CNV Profiles 1.0 1.71329
Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.433
signal transducer activity GO Molecular Function Annotations 2015 1.0 null
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.981953
SKLMS1 CCLE Cell Line Gene CNV Profiles -1.0 -2.13951
singlenucleotide GeneRIF Biological Term Annotations 1.0 null
Hyperglycemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.284
LTBR_INHIBITION - 3 Day_GDS2004_735_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
GSE264621_1_v_6_secretin_human RummaGEO Drug Perturbation Signatures -1.0 null
KARPAS-1106P COSMIC Cell Line Gene Mutation Profiles 1.0 null
GSE109285_5_v_2_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null
H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
Gastrin-CREB signalling pathway via PKC and MAPK Reactome Pathways 2014 1.0 null
receptor activity GO Molecular Function Annotations 2015 1.0 null
metal ion homeostasis GO Biological Process Annotations 2015 1.0 null
form GeneRIF Biological Term Annotations 1.0 null
Pancreas-pancreatic alpha cell Tabula Sapiens Gene-Cell Associations 1.0 0.650527
NMB DepMap CRISPR Gene Dependency 1.0 2.1575
KYSE150 CCLE Cell Line Gene CNV Profiles -1.0 -1.57302
regulation of cell population proliferation GO Biological Process Annotations 2025 1.0 null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
19808870-ST1 GeneSigDB Published Gene Signatures 1.0 null
BRD-K92239253 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57487
BRD-K76508844 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09776
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Br_Heat_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null
H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.763226
Pituitary carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.15
avpr1b GeneRIF Biological Term Annotations 1.0 null
plasma membrane part GO Cellular Component Annotations 2015 1.0 null
GPCR downstream signaling Reactome Pathways 2014 1.0 null
HNF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36517
NPIPB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31099
HO1U1 DepMap CRISPR Gene Dependency 1.0 2.9621
Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.647
RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6087
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null
JHOM2B CCLE Cell Line Gene Expression Profiles -1.0 -1.59438
BRD-K64451058 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20474
Pituitary adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.928
NB1 CCLE Cell Line Gene CNV Profiles 1.0 1.53687
panic disorder GAD Gene-Disease Associations 1.0 null
Congestive Heart Failure DisGeNET Gene-Disease Associations 1.0 null
GSE178560_0_v_1_irf7_mouse RummaGEO Gene Perturbation Signatures -1.0 null
positive regulation of phospholipase activity GO Biological Process Annotations 2023 1.0 null
DFCI024 CCLE Cell Line Gene Expression Profiles 1.0 1.40687
membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.254017
H3K36me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
ACP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06333
H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null
JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
BRD-K33710385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09698
affective GeneRIF Biological Term Annotations 1.0 null
hsa-miR-1827 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155
Alcohol dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.414
AP3D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65996
stomach GTEx Tissue Gene Expression Profiles 1.0 1.093
ZNF701 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 133.416
MIXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31527
Endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091
Inappropriate ADH syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.57
HEMK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0104
KYSE-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null
MAPK8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19544
BRD-K77601667 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24222
BRD-A34842997 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01749
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
adrenal gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.1009
KLC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85579
RHOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25274
brownfat BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.864025
ELK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42808
H3K4me1_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
CHGB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34995
ZNF621 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24017
BL-70 COSMIC Cell Line Gene Mutation Profiles 1.0 null
GSE152441,GSE152442_7_v_5_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null
Median eminence TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.936
NB7 COSMIC Cell Line Gene Mutation Profiles 1.0 null
regulation of systemic arterial blood pressure by hormone GO Biological Process Annotations 2025 1.0 null
Autosomal dominant polycystic kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.173
MM370 DepMap CRISPR Gene Dependency 1.0 2.53019
intracellular part GO Cellular Component Annotations 2015 1.0 null
organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054016
membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342
ARFGEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18218
J82 GDSC Cell Line Gene Expression Profiles -1.0 -1.64585
langerhans GeneRIF Biological Term Annotations 1.0 null
signal transduction GO Biological Process Annotations 2015 1.0 null
membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null
abnormal circulating glucocorticoid level MPO Gene-Phenotype Associations 1.0 null
REEP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39916
BRD-K63277230 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35496
Chronic kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017
BRD-K53121826 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36769
SMYD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22957
FOS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13935
H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
SNU5 DepMap CRISPR Gene Dependency 1.0 4.05732
BRD-K91511557 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15224
HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.794
ZNF467 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65467
Calcium HMDB Metabolites of Enzymes 1.0 null
[PHAA1,D-TYR(ME)2,ARG6,TYR-NH29]AVP DGIdb Drug Targets 2026 1.0 0.420095
IRX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88158
H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Infundibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.861
H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null
CRCGN016_MCF10A.TP53.M_24H:P24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.1441
LGALS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90024
H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
ENTPD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22295
CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.5723
BRD-A25883214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07488
positive regulation of phospholipase c activity GO Biological Process Annotations 2015 1.0 null
(R)-PIA DGIdb Drug Targets 2026 1.0 0.157536
Familial combined hyperlipidaemia_lymphoblast_GSE1010 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.18758
MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15336
response to organic substance GO Biological Process Annotations 2015 1.0 null
evidence GeneRIF Biological Term Annotations 1.0 null
BRD-K80622681 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08549
Terlipressin HMDB Metabolites of Enzymes 1.0 null
CDK4_knockdown_133_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.60976
BRD-K69437108 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49401
Hyperplasia CTD Gene-Disease Associations 1.0 1.21919
BRD-K23196166 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1057
LN215 CCLE Cell Line Gene Expression Profiles 1.0 1.35972
KDM4A ENCODE Transcription Factor Targets 1.0 null
HNF4G_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
splitomicin-661 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null
MDAMB453 CCLE Cell Line Gene CNV Profiles 1.0 1.864
HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Heart Failure DisGeNET Gene-Disease Associations 1.0 null
BRD-A40022950 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26096
CTBP2 ENCODE Transcription Factor Targets 1.0 null
hypoglycemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.227297
Hormone producing pituitary cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.451
GSE68925_1_v_0_fasudil_human RummaGEO Drug Perturbation Signatures -1.0 null
HSDL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34264
BRD-K30895360 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24883
FAM219B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8895
CRCGN015_MCF10A_48H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.22786
BRD-A20305532 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07392
NELIVAPTAN DGIdb Drug Targets 2026 1.0 0.756171
SUZ12 ENCODE Transcription Factor Targets 1.0 null
HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0
paclitaxel-1959 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
ZNF257 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 85.5803
CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
KDM5B ENCODE Transcription Factor Targets 1.0 null
susceptibility GeneRIF Biological Term Annotations 1.0 null
plasma membrane LOCATE Curated Protein Localization Annotations 1.0 null
PTPRU MSigDB Cancer Gene Co-expression Modules 1.0 null
GSE217776,GSE217829_4_v_6_sgf29_human RummaGEO Gene Perturbation Signatures -1.0 null
PIGS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71601
disorder GeneRIF Biological Term Annotations 1.0 null
Macula densa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.828
Agnosia DisGeNET Gene-Disease Associations 1.0 null
SUIT-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948179
Vomiting CTD Gene-Disease Associations 1.0 1.05052
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4856-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51043
Prediabetes syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.066
Tenia tecta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.659
ACTN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90997
SNU119 CCLE Cell Line Gene Expression Profiles -1.0 -2.05915
ChIP_ZFP42_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null
[3H]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
GARRE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81802
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
BRD-K62976536 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25102
RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null
CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null
NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.946081
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
abnormal hormone level MPO Gene-Phenotype Associations 1.0 null
HNF4G ENCODE Transcription Factor Targets 1.0 null
FOXP3_ABLATION_GDS2525_64_mouse_mature regulatory T cells (Treg) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6013-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
response to organonitrogen compound GO Biological Process Annotations 2015 1.0 null
G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07756
MLXIPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70456
CORL105 CCLE Cell Line Gene Expression Profiles -1.0 -1.53324
BRD-K17107214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00249
GSE195568_6_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null
Adrenalgland BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.22924
SURF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42513
Blood Coagulation Disorders CTD Gene-Disease Associations 1.0 1.04389
IKZF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64067
RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
SLC transporter disorders Reactome Pathways 2024 1.0 null
Central diabetes insipidus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.239
CBX2 ENCODE Transcription Factor Targets 1.0 null
MACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08599
MYF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94761
POU2F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24261
effect GeneRIF Biological Term Annotations 1.0 null
PMC4747358__F3 PFOCR Pathway Figure Associations 2023 1.0 null
BRD-A38066207 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08445
kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.327164
NOL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54545
abnormal social investigation MGI Mouse Phenotype Associations 2023 1.0 null
BRD-K82681356 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34234
CAL148 CCLE Cell Line Gene CNV Profiles 1.0 1.60085
Meynert's basal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.716
gh1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.157
BRD-K87339026 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46935
CHD7 ENCODE Transcription Factor Targets 1.0 null
sodium phenylbutyrate-407 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
E2F1 JASPAR Predicted Transcription Factor Targets 1.0 null
Diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.443
H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
ST486 GDSC Cell Line Gene Expression Profiles 1.0 1.73078
PMC12021929-Table1.docx-0-E2F3_E2F3 Rummagene Transcription Factor Associations 2026 1.0 null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4853-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
Enteroendocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.925
BRD-K90155857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01501
Posterior cingulate cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788
UNC93B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06379
GATA6-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null
abnormal blood homeostasis MPO Gene-Phenotype Associations 1.0 null
HMGA2 MSigDB Cancer Gene Co-expression Modules 1.0 null
H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
SMARCD1 MSigDB Cancer Gene Co-expression Modules 1.0 null
GSE168807_6_v_7_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null
DNM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81683
head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.23004
H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.059202
H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null
C3orf80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11113
NECA DGIdb Drug Targets 2026 1.0 0.157536
EPB41L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97883
H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
BRPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86667
GSE239844_6_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null
tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null
PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
PDE6G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08147
WSCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88651
dexpropranolol-6130 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null
KDM5A ENCODE Transcription Factor Targets 1.0 null
c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.01996
SNU1040 CCLE Cell Line Gene Expression Profiles 1.0 1.65764
H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null
GSE248858_5_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null
BRD-K09137343 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34927
CHSY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47385
d[D-Phe2]AVP Guide to Pharmacology Chemical Ligands of Receptors 1.0 null
PMC3877719__F1 PFOCR Pathway Figure Associations 2023 1.0 null
BRD-K02471501 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36366
GSE234289_5_v_2_rfx6_human RummaGEO Gene Perturbation Signatures -1.0 null
BRD-K49666076 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1517
Neurohypophyseal diabetes insipidus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.047
REST_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null
Large_Intestine-intestinal enteroendocrine cell Tabula Sapiens Gene-Cell Associations 1.0 3.1597
CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
GSE163240_3_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null
disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.540055
ZNF706 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31039
496100561_PCx_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.6382
CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null
response to endogenous stimulus GO Biological Process Annotations 2015 1.0 null
GSE225901_0_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null
protein kinase C binding GO Molecular Function Annotations 2025 1.0 null
Vasopressin receptor InterPro Predicted Protein Domain Annotations 1.0 null
Coronary artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.148
H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null
homeostatic process GO Biological Process Annotations 2015 1.0 null
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null
ZNRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82246
constitutive GeneRIF Biological Term Annotations 1.0 null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
WDR86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87302
ALDOA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53639
A172 BioGPS Cell Line Gene Expression Profiles 1.0 0.945786
PDZD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19298
RBL1_KO_GDS1931_740_mouse_Neurospheres (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null
Social Perception HuGE Navigator Gene-Phenotype Associations 1.0 null
ANKRD16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8419
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null
CDH5 MSigDB Cancer Gene Co-expression Modules 1.0 null
decreased circulating adrenocorticotropin level MGI Mouse Phenotype Associations 2023 1.0 null
UMRC2 CCLE Cell Line Gene Expression Profiles 1.0 1.57196
pituitary adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.791721
MIS18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22488
SMIM30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71257
TRPM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55749
TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null