association	dataset	threshold value	standardized value
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Essential hypertension (time to event)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09959
PMC11079244-Data_Sheet_2.XLSX-Supplementary_Table_2-Supplementary_Table_2_Genetic_instruments_of_plasma_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49246
short frontal bone	MGI Mouse Phenotype Associations 2023	1.0	null
Cerebral Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Anterior Chamber Synechiae	DisGeNET Gene-Disease Associations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Banded collagen fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.134
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Age related macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
Short Palpebral Fissure	DisGeNET Gene-Phenotype Associations	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13519
GSE234334,GSE234336_1_v_0_zhx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87404,GSE87812_2_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Feeding Difficulties In Infancy	DisGeNET Gene-Phenotype Associations	1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Carbohydrate metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Congenital disorder of glycosylation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.218
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Short Nose	DisGeNET Gene-Phenotype Associations	1.0	null
Syndromic microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
ED-81-ZH14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300396
Intrinsic component of Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_18_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S22-Table_S22_MR_resluts_of_blood_proteins_in_AGES_project_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149903_3_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Astrocyte_Embryonic prefrontal cortex_Human	CellMarker Gene-Cell Type Associations	1.0	null
Desbuquois dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
GSE178340_1_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal cranium size	MGI Mouse Phenotype Associations 2023	1.0	null
Oculodentodigital dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
GSE240439_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NMCG1	DepMap CRISPR Gene Dependency	1.0	6.56124
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14384
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.2642
NCIH661	DepMap CRISPR Gene Dependency	1.0	2.01292
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9646482-mmc13.xlsx-ST13B_AA-specific-regions-Unnamed_13_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1316
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7706
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kahrizi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9385
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Polio And Post-Polio Syndrome	DisGeNET Gene-Disease Associations	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12108
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4936
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18415
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44711
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S26-Table_S26_MR_resluts_of_blood_proteins_in_AGES_project_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7224
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Short Metacarpal	DisGeNET Gene-Phenotype Associations	1.0	null
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9142
Arthropathy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.525
CENP-A containing nucleosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.826
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Trichohepatoenteric Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4B-Up_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pterygium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_lowerRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hydrophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.876
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4009
SEC61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02483
Atrial Septal Defect	DisGeNET Gene-Disease Associations	1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Syndactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11399
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
MCF7	DepMap CRISPR Gene Dependency	1.0	2.80227
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.693
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8264
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8042171__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GSE147366_3_v_0_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Epiphyseal growth plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04034
abnormal craniofacial morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Esotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LI7	DepMap CRISPR Gene Dependency	1.0	2.67204
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.212
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225896
SNU81	DepMap CRISPR Gene Dependency	1.0	15.6783
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kuhnt-Junius degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.525
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0771
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.702
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1009
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8853
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Microtia, Second Degree	DisGeNET Gene-Phenotype Associations	1.0	null
Brachydactyly	DisGeNET Gene-Disease Associations	1.0	null
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cranioectodermal dysplasia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
Post-translational protein modification	Reactome Pathways 2024	1.0	null
Polyhydramnios	DisGeNET Gene-Phenotype Associations	1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Syndromic microphthalmia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Strabismus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Birth Length Less Than 3Rd Percentile	DisGeNET Gene-Phenotype Associations	1.0	null
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8954
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Short Palm	DisGeNET Gene-Phenotype Associations	1.0	null
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9903
Macrostomia	DisGeNET Gene-Disease Associations	1.0	null
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
Exaggerated Cupid'S Bow	DisGeNET Gene-Phenotype Associations	1.0	null
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bilobate Gallbladder	DisGeNET Gene-Disease Associations	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1976
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S24-Table_S24_MR_resluts_of_blood_proteins_in_AGES_project_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
CE-18-CG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2226
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WC-75-IK59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20864
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.60655
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6046
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4679
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
Short Foot	DisGeNET Gene-Phenotype Associations	1.0	null
GSE210101,GSE210114_1_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SHP77	DepMap CRISPR Gene Dependency	1.0	5.18585
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterior chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
ZNF516	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01946
GSE210101,GSE210114_4_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.457
Visual Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
HUWE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00045
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Integral component of Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02523
THNSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16962
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE189653,GSE203344_5_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0893
PMC8803621-mmc6.xlsx-Sup_Fig5A_genes_list-Genes_with_following_MEF2_motifs_around_their_TSS_CTAWWWATA_RSRFC4_Q2_MEF2_Q6_01_MEF2_03_MEF2_02_RSRFC4_Q2_from_GSEA_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_lowerRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8042171__F2	PFOCR Pathway Figure Associations 2024	1.0	null
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202815
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.9854
white spotting	MGI Mouse Phenotype Associations 2023	1.0	null
UA-39-TN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260372
Other types of O-glycan biosynthesis	KEGG Pathways 2026	1.0	null
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.05
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.702
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1905
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	12.5714
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10771430-42003_2023_5737_MOESM3_ESM.xlsx-S4-MR-AAM-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262376
Fetal Growth Retardation	DisGeNET Gene-Phenotype Associations	1.0	null
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HB-24-GP45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251883
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.624
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.807
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24934
GSE80222_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Megalocornea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22803
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRA_RXRA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182854_2_v_0_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SQ1_LUNG	CCLE Cell Line Proteomics	1.0	2.88248
HA1E	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
Interphase microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
PMC9046280-41467_2022_29963_MOESM8_ESM.xlsx-Supplementary_Fig_4B-Genes_annotated_to_enhancers_bound_by_ASCL1_ChIP_and_lost_expression_in_42D_K_D_ASCL1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spondyloepimetaphyseal dysplasia with joint laxity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12288
Primary open angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0917
GSE188570,GSE188571_5_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ectoplacental cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9981
Congenital disorder of glycosylation	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
Postnatal Growth Retardation	DisGeNET Gene-Phenotype Associations	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0609
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.05
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09841
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sacral Dimple	DisGeNET Gene-Phenotype Associations	1.0	null
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Menstrual Spotting	DisGeNET Gene-Phenotype Associations	1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Compound-1a	DeepCoverMOA Drug Mechanisms of Action	1.0	0.55
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Krause-Kivlin Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hydronephrosis	DisGeNET Gene-Disease Associations	1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Long Philtrum	DisGeNET Gene-Phenotype Associations	1.0	null
Lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
Geleophysic dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.181
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12351
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5032
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
GSE190947_1_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Renal Hypoplasia/Aplasia	DisGeNET Gene-Phenotype Associations	1.0	null
Exudative Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Peters anomaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.266
Cerebrooculofacioskeletal syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37623
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43608
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.654
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sturge-Weber syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
MELHO	DepMap CRISPR Gene Dependency	1.0	2.28227
Exudative Age-Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4627
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82316
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE208634_1_v_2_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Patent ductus arteriosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3766
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_5_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04133
Hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
Galectin lattice	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2882	DepMap CRISPR Gene Dependency	1.0	3.88683
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UDP-glycosyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08446
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5853
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274673
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anemia	DisGeNET Gene-Disease Associations	1.0	null
Thin Upper Lip Vermilion	DisGeNET Gene-Phenotype Associations	1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
IA-27-CK10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274623
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90257
CBIO	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213449
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21744
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7781
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital Hypothyroidism	DisGeNET Gene-Disease Associations	1.0	null
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
GSE209698_0_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23321
Umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
Stenosis	DisGeNET Gene-Disease Associations	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spina Bifida	DisGeNET Gene-Disease Associations	1.0	null
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protein O-linked fucosylation	GO Biological Process Annotations 2025	1.0	null
PMC4686057-pone.0145107.s001.xlsx-PAA-CAA-Unnamed_0_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.84
OCUBM	DepMap CRISPR Gene Dependency	1.0	2.19958
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174383_2_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital disorder of glycosylation type IIh	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
IRF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29464
Diseases of glycosylation	Reactome Pathways 2024	1.0	null
GSE142210_4_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	3.27763
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SELENOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8241
Congenital Exomphalos	DisGeNET Gene-Disease Associations	1.0	null
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00768
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hydrocephalus	DisGeNET Gene-Disease Associations	1.0	null
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238161
PMC11462941-CAS-115-2947-s001.pdf-150-LBX2-AS1_LBX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
short facial bone	MGI Mouse Phenotype Associations 2023	1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02231
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2948
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUCLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05846
GSE210667_3_v_2_rfx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMIM30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56332
Retinal pigment epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.702
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Conductive Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129465_3_v_2_phf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143692_2_v_1_trim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
syndactyly	MGI Mouse Phenotype Associations 2023	1.0	null
acetylglucosaminyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	2.39783
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05811
Diseases associated with O-glycosylation of proteins	Reactome Pathways 2024	1.0	null
GSE65617_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Upward Slant Of Palpebral Fissure	DisGeNET Gene-Phenotype Associations	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.1
decreased length of long bones	MGI Mouse Phenotype Associations 2023	1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Huperzine A	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100571_FWM_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28735
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125211_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nonpigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
Talipes	DisGeNET Gene-Disease Associations	1.0	null
Gillespie syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Paranode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
Septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
broad nasal bone	MGI Mouse Phenotype Associations 2023	1.0	null
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60027
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ZIC3_ZIC3	Rummagene Transcription Factor Associations 2026	1.0	null
Prominent Forehead	DisGeNET Gene-Phenotype Associations	1.0	null
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.24672
Cataract	DisGeNET Gene-Disease Associations	1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Abnormal Pulmonary Vein Morphology	DisGeNET Gene-Phenotype Associations	1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63003
HSCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16231
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11615
Dilated Ventricles (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH650_LUNG	CCLE Cell Line Proteomics	1.0	2.24466
Walker-Warburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
KPNYS	DepMap CRISPR Gene Dependency	1.0	2.06761
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JHH1_LIVER	CCLE Cell Line Proteomics	1.0	2.80158
GSE166914_1_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23596
Anus, Imperforate	DisGeNET Gene-Disease Associations	1.0	null
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18682
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2516
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1785
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Buphthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.877
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2983
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4
Axenfeld-Rieger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.154
Peters plus syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
PMC11588066-pnas.2410331121.sapp.pdf-73-ZFPM2_ZFPM2	Rummagene Transcription Factor Associations 2026	1.0	null
Posteriorly Rotated Ear	DisGeNET Gene-Disease Associations	1.0	null
abnormal sphenoid bone morphology	MGI Mouse Phenotype Associations 2023	1.0	null
EOMES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00348
Lens epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.129
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Corneal staphyloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.034
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5303
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316762
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_5_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7867
MCM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4864
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.64904
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12749580-42003_2025_9274_MOESM5_ESM.xls-Supplementary_Data_2A-Supplementary_Table2A_Full_results_of_the_proteome-wide_MR_in_deCODE_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital Separation Excessive	DisGeNET Gene-Phenotype Associations	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
decreased body size	MGI Mouse Phenotype Associations 2023	1.0	null
endoplasmic reticulum membrane	GO Cellular Component Annotations 2023	1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GM1 gangliosidosis type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3209
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Anteriorly Placed Anus	DisGeNET Gene-Phenotype Associations	1.0	null
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.24
GSE200502_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital disorder of glycosylation type IIa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital disorder of glycosylation type IIl	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3324
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1001
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Avagacestat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113283
brachydactyly	MGI Mouse Phenotype Associations 2023	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7682
NCIH2009_LUNG	CCLE Cell Line Proteomics	1.0	4.16839
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1126
STYXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05565
PMC11110418-12864_2024_10412_MOESM1_ESM.xlsx-S_Table_2-Supplementary_Table_2_Detailes_of_the_instrumental_variables_of_plasma_proteins_used_in_discovery_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bicuspid Pulmonary Valve	DisGeNET Gene-Disease Associations	1.0	null
GSE84462,GSE84762_0_v_7_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brachycephaly	DisGeNET Gene-Disease Associations	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345069
ALS2CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02996
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12858
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260649
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01624
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363208
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Spina bifida occulta	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93168
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09146
GSE123943_4_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A172_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	3.05629
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157282_0_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_11_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36429
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1156
GSE210101,GSE210114_4_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Aqueous misdirection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.512
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Conoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215372
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
BICR78	DepMap CRISPR Gene Dependency	1.0	2.2246
GSE152432_3_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6488
open-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
GSE221577_2_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
CGRP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
GSE87404,GSE87812_2_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Protruding Ear	DisGeNET Gene-Phenotype Associations	1.0	null
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNUC5_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.57451
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
QE-48-NG07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225542
CORL47_LUNG	CCLE Cell Line Proteomics	1.0	3.05629
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Exoerythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of metabolism	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Microcornea	DisGeNET Gene-Disease Associations	1.0	null
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
Round Face	DisGeNET Gene-Phenotype Associations	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nipple	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39969
protein O-linked glycosylation	GO Biological Process Annotations 2025	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
Abnormality Of The Skeletal System	DisGeNET Gene-Disease Associations	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261005
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.037
Frank-Ter Haar syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
GSE144115_4_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CASKIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4117
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52032
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17725
Age-related macular degeneration	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chromosome, centromeric core domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
NSUN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00088
MAN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0717
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
PMC11659389-42003_2024_7403_MOESM4_ESM.xlsx-5-Supplementary_Table_5_Result_and_IV_SNPs_of_the_primary_proteome-wide_MR_of_MM_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196699_7_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypospadias	DisGeNET Gene-Disease Associations	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11776
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Micrognathism	DisGeNET Gene-Disease Associations	1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Weill-Marchesani syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
Rhizomelia	DisGeNET Gene-Disease Associations	1.0	null
Phacolytic glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
Multicystic Dysplastic Kidney	DisGeNET Gene-Disease Associations	1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211474,GSE212779_8_v_10_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152432_9_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.865
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7219
Corneal Opacity	DisGeNET Gene-Phenotype Associations	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.525
Clitoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
PMC11659389-42003_2024_7403_MOESM4_ESM.xlsx-3-Supplementary_Table_3_Results_and_IV_SNPs_of_the_primary_proteome-wide_MR_of_BCC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223893_4_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59426
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
Collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
O-linked glycosylation	Reactome Pathways 2024	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.6742
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.525
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Corneal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Otopalatodigital syndrome spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
decreased long bone epiphyseal plate size	MGI Mouse Phenotype Associations 2023	1.0	null
Interstitial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.544
KP3	DepMap CRISPR Gene Dependency	1.0	2.16664
Agenesis	DisGeNET Gene-Phenotype Associations	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	195.543
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11516
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5388
Wide Spaced Nipples	DisGeNET Gene-Phenotype Associations	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283002
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7571
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4974
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312955
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-POU5F1_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE223008_6_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital disorder of glycosylation type IIm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Weight Decreased	DisGeNET Gene-Phenotype Associations	1.0	null
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Age Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04244
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S23-Table_S23_MR_resluts_of_blood_proteins_in_AGES_project_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2639
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain small vessel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.26495
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166308_1_v_0_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7714
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7339
Coloboma Of Iris	DisGeNET Gene-Disease Associations	1.0	null
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100638_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0154
Collagen type I trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.649
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
facial asymmetry	MGI Mouse Phenotype Associations 2023	1.0	null
THP1	DepMap CRISPR Gene Dependency	1.0	2.4959
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254687
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Anomalous Pulmonary Artery	DisGeNET Gene-Disease Associations	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
Sclerocornea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.369
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5902498-41598_2018_24445_MOESM3_ESM.xlsx-GATA1_ChIP-Seq_peaks-Unnamed_5_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.3258
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Irido-Corneo-Trabecular Dysgenesis (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-NFATC3_mod_NFATC3	Rummagene Transcription Factor Associations 2026	1.0	null
increased cranium width	MGI Mouse Phenotype Associations 2023	1.0	null
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01901
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
Congenital disorder of glycosylation type IIc	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2966
Keratoconus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01891
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Cleft Lip	DisGeNET Gene-Disease Associations	1.0	null
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6167
PMC7519331-pnas.1921408117.sd18.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
8855_TFPT_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.31821
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5332
GSE226355,GSE226357_3_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	4.66698
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.928
PMC9314343-41467_2022_31892_MOESM8_ESM.xlsx-Fig7e-CTCF_in_promoter_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.702
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cleft lip	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.4
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0279
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1072
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.197
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
EMTOKA	DepMap CRISPR Gene Dependency	1.0	2.33239
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7157
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior segment dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.976
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Baraitser-Winter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.096
Advanced age-related macular degeneration	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
PMC10913870-pr3c00632_si_001.pdf-2-ZNF408_ZNF408	Rummagene Transcription Factor Associations 2026	1.0	null
Blepharophimosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.65681
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.3473
GSE147366_3_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2032
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25619
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PNPLA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60922
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09648
CYP2R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87669
GSE169697,GSE169725_0_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206911
PMC4395516__F7	PFOCR Pathway Figure Associations 2024	1.0	null
Deprivation amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151612_0_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital Pectus Excavatum	DisGeNET Gene-Disease Associations	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383539
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8756
TC71	DepMap CRISPR Gene Dependency	1.0	2.4673
Avosentan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
GSE134375_6_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218206
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.8995
Abnormality Of Pelvic Girdle Bone Morphology	DisGeNET Gene-Disease Associations	1.0	null
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Peters plus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.904
protein O-linked glycosylation	GO Biological Process Annotations 2023	1.0	null
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KYO1	DepMap CRISPR Gene Dependency	1.0	2.2951
GSE153010_1_v_0_sprr2f_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.934
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40762
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298243
Spondylocostal dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.761
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.23
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5896
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
GSE226091,GSE226092_3_v_2_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.0
Congenital aphakia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.944
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
increased cranium height	MGI Mouse Phenotype Associations 2023	1.0	null
GSE210101,GSE210114_7_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3931
GSE157594_5_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.702
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.956
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4832
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.55596
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46375
chr13_31300166_C_T_b38	GTEx eQTL 2025	1.0	1.1816
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.0822
Lateral cystocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.069
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
wide frontal bone	MGI Mouse Phenotype Associations 2023	1.0	null
chr13_31248530_C_G_b38	GTEx eQTL 2025	1.0	1.13442
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lip disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.115
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8025
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Aplasia/Hypoplasia Of The Corpus Callosum	DisGeNET Gene-Phenotype Associations	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7003
PMC10534007-Table_2.xlsx-S2_overlap_MSC_down_B_V-395_common_elements_in_VM-CUB1_MSC_down_and_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Synostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cleft Palate	DisGeNET Gene-Disease Associations	1.0	null
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.527
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE220520_3_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Embryonic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.915
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35333
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
SKUT1	DepMap CRISPR Gene Dependency	1.0	2.62718
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S25-Table_S25_MR_resluts_of_blood_proteins_in_AGES_project_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_0_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
Velum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.1849
C33A	DepMap CRISPR Gene Dependency	1.0	2.99183
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital disorder of glycosylation type IIf	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4874
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64192
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Preauricular Dimple	DisGeNET Gene-Disease Associations	1.0	null
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08417
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
protein O-linked fucosylation	GO Biological Process Annotations 2023	1.0	null
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12775
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Iris disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.117
PMC7780220-12943_2020_1301_MOESM8_ESM.xlsx-Fig_3A_RNA-seq_DEGs-Summary_701_LPS-induced_DEGs_361_THZ1-sensitive_DEGs_in_blue_of_macrophages_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CENP-A containing chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
hexosyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
DBF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51257
Geographic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
hydrocephaly	MGI Mouse Phenotype Associations 2023	1.0	null
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11459707-12890_2024_3289_MOESM1_ESM.xlsx-TableS3_MR_results-Supplementary_Table3_The_causal_effect_of_proteins_on_IPF_risk_from_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11767
Peters plus syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Short Neck	DisGeNET Gene-Phenotype Associations	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hydrocephallus	DisGeNET Gene-Disease Associations	1.0	null
abnormal intramembranous bone ossification	MGI Mouse Phenotype Associations 2023	1.0	null
GSE193541_1_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Micromelia	DisGeNET Gene-Disease Associations	1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thrombotic thrombocytopenic purpura	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Conjunctivochalasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Aniridia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
MCF7_Streptozotocin_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154325
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3978
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51107
UMUC9	DepMap CRISPR Gene Dependency	1.0	2.02179
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Congenital disorder of glycosylation type IIe	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hernia	DisGeNET Gene-Phenotype Associations	1.0	null
Long Face	DisGeNET Gene-Phenotype Associations	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5201
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
NCIH3122	DepMap CRISPR Gene Dependency	1.0	2.27281
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44391
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.702
Ehlers-Danlos syndrome dermatosparaxis type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9326
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_12_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital disorder of glycosylation type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AMO1	DepMap CRISPR Gene Dependency	1.0	2.30173
Spondyloepimetaphyseal dysplasia with joint laxity type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
Clinodactyly	DisGeNET Gene-Disease Associations	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.776048
Macrocephaly	DisGeNET Gene-Disease Associations	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49424
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormal skeleton morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Axenfeld-Rieger syndrome type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
Tek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
TFB1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01545
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
Glucosidase II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.915
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endoplasmic reticulum quality control compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Limited Elbow Movement	DisGeNET Gene-Phenotype Associations	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
L-741	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.46
TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.25574
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62625
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Broad Foot	DisGeNET Gene-Phenotype Associations	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.7752
Congenital Hemivertebra	DisGeNET Gene-Disease Associations	1.0	null
Congenital disorder of glycosylation type IIb	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
abnormal nasal bone morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.078
GSE109530,GSE109531_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chromosome 3q29 microduplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
monolayer-surrounded lipid storage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.71
RH28	DepMap CRISPR Gene Dependency	1.0	3.21098
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8016
PMC7519331-pnas.1921408117.sd11.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4395516__F7	PFOCR Pathway Figure Associations 2023	1.0	null
Blepharoptosis	DisGeNET Gene-Disease Associations	1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mannan polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63376
U2OS	DepMap CRISPR Gene Dependency	1.0	3.52627
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4404
Multiple congenital anomalies-hypotonia-seizures syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
COLO829_SKIN	CCLE Cell Line Proteomics	1.0	3.14315
GSE95688_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LCLC103H	DepMap CRISPR Gene Dependency	1.0	2.54587
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	1.05306
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.66356
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11659389-42003_2024_7403_MOESM4_ESM.xlsx-4-Supplementary_Table_4_Result_of_the_primary_proteome-wide_MR_of_SCC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210101,GSE210114_11_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DYNLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19728
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39205
GSE203308_6_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Juvenile glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355016
PMC11518751-Table1.xlsx-Table_S1_IV_for_MR-exposure_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29196
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8569
Joint Laxity	DisGeNET Gene-Phenotype Associations	1.0	null
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218572
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.9289
PMC11347378-41375_2024_2357_MOESM4_ESM.xlsx-Fig_7A_S8A_public_RNA-seq_DEGs-TFDP1_KO_HAP_cells_Human_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221353
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Golgi cis cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
Degeneration of macula and posterior pole	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45896
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.218
Potter's syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
NCIH1437_LUNG	CCLE Cell Line Proteomics	1.0	8.59051
GSE156667_0_v_1_lrrc8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Metabolism of proteins	Reactome Pathways 2024	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
X-linked endothelial corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE186044_4_v_2_tcra_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Broad Neck	DisGeNET Gene-Phenotype Associations	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thin Lips	DisGeNET Gene-Phenotype Associations	1.0	null
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29082
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.087
Congenital disorder of glycosylation type IIg	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Osteogenesis imperfecta type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Congenital disorder of glycosylation type IId	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9428
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Short Frenulum Of Tongue	DisGeNET Gene-Phenotype Associations	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Geleophysic dysplasia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_downregulated_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90273
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.171
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41594
O-glycosylation of TSR domain-containing proteins	Reactome Pathways 2024	1.0	null
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33302
Blood protein levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.8699
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.986
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7512
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Corpus callosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
MESP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22581
Oligosaccharyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
GSE174383_2_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.9942
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pulmonary Stenosis	DisGeNET Gene-Disease Associations	1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Thrombospondin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.438
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8859
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
Short Columella	DisGeNET Gene-Phenotype Associations	1.0	null
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0682
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18222
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2482
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.702
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4967
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
Palate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.19
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.0179
Cerebral Cortical Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Myopia	DisGeNET Gene-Disease Associations	1.0	null
Diseases of metabolism	Reactome Pathways 2024	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital Hypoplasia Of Kidney	DisGeNET Gene-Disease Associations	1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.512
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01667
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.71405
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S3.xlsx-Table_S3F-Supplemental_Table_S3F_ZFX_binding_pattern_clustering_information_for_genes_with_promoters_bound_by_ZFX_related_to_Figure_2I_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
Cornea plana	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
GSE153189_2_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06452
chr13_31278139_A_G_b38	GTEx eQTL 2025	1.0	1.31134
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5550424-41467_2017_212_MOESM4_ESM.xlsx-Hematlas-Genesets-POU5F1_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11699013-12672_2024_1699_MOESM1_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_The_association_between_proteins_and_CLL_in_the_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36166
GSE95826_4_v_1_tcra_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PACADD188	DepMap CRISPR Gene Dependency	1.0	3.64654
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229309
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10645393-jci-133-169200-s102.xlsx-Table_S14_AR-V_DNA-PK_DEGs-Supplementary_Table_14_Overlapping_DEG_list_from_CWR22Rv1-AR-EK_cells_depleted_of_AR-V7_and_treated_with_DNA-PK_inhibitor_NU5455_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4623
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.311
Eye degenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
Prolapse of female genital organ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.639
Double Ureter	DisGeNET Gene-Disease Associations	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3074
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
MKN45	DepMap CRISPR Gene Dependency	1.0	3.08686
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75766
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary congenital glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.027
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9038526-mmc1.xlsx-postCOVID_LPS_vs_healthy_L-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42341
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7039
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Accommodative esotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.942
Chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3712
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269091
Single Transverse Palmar Crease	DisGeNET Gene-Phenotype Associations	1.0	null
NCIH2452	DepMap CRISPR Gene Dependency	1.0	2.56575
General risk tolerance (MTAG)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.881
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	201.711
WAGR syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48132
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08194
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.569
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23812
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22947
GSE143944_1_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Syndromic microphthalmia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
short basicranium	MGI Mouse Phenotype Associations 2023	1.0	null
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30611
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.42
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Corneal endothelial dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9265
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	201.197
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5845
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Reduced Fetal Movement	DisGeNET Gene-Phenotype Associations	1.0	null
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fucosylation	GO Biological Process Annotations 2025	1.0	null
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
Age related macular degeneration 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.703
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.522
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100487_HIP_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.61422
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Umbilical hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
TRNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88178
Infantile Uterus	DisGeNET Gene-Disease Associations	1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7873
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_5_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BLOC-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.55
CALU6_LUNG	CCLE Cell Line Proteomics	1.0	2.82189
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
External ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.716
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Semaphorin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.966
Short Metatarsal	DisGeNET Gene-Phenotype Associations	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4261
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7778
Anteverted Nostril	DisGeNET Gene-Phenotype Associations	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7877
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_12_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.59766
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65354
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49896
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06484
LD-69-ZV56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216674
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Retinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
Wide Anterior Fontanel	DisGeNET Gene-Phenotype Associations	1.0	null
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3584
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypospadias	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
Preauricular Skin Tag	DisGeNET Gene-Phenotype Associations	1.0	null
short face	MGI Mouse Phenotype Associations 2023	1.0	null
chr13_31366599_C_T_b38	GTEx eQTL 2025	1.0	2.60735
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_30_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
dolichol-phosphate-mannose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.652
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340167
MMP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64431
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
GSE179031_3_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.512
Cavum septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.887
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Optic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Depressed Nasal Bridge	DisGeNET Gene-Phenotype Associations	1.0	null
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50346
496100632_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11697
Fibrillar collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.196
NCI-H2228 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital Coloboma Of Iris	DisGeNET Gene-Disease Associations	1.0	null
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11839
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275794
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5906
PMC10891378-tau-13-01-91-supplementary.pdf-50-PURA_PURA	Rummagene Transcription Factor Associations 2026	1.0	null
Autism	DisGeNET Gene-Disease Associations	1.0	null
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28536
Phacogenic glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9235
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.645
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.157
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6856
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35652
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.05
PMC12486367-Supplementary_Data2.pdf-397-MYNN_MYNN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.365
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
PSMA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52758
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.535
KASUMI1	DepMap CRISPR Gene Dependency	1.0	2.49914
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60883
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OCILY3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	4.74605
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.6998
GSE212074_0_v_1_pus1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4963
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UDP-glycosyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
NUDT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06819
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203308_1_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-521-ZSCAN2_ZSCAN2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hydronephrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
YSCCC	DepMap CRISPR Gene Dependency	1.0	2.11865
SEPTIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10547
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Conical Incisor	DisGeNET Gene-Phenotype Associations	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Charcot-Marie-Tooth disease type 4B2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PANC0327	DepMap CRISPR Gene Dependency	1.0	3.44698
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATP5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03247
Syndactyly	DisGeNET Gene-Disease Associations	1.0	null
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Posterior polar cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
1,3-beta-D-glucan synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.765
GSE248858_5_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF724	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17267
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Posterior polymorphous corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
BICR10	DepMap CRISPR Gene Dependency	1.0	4.03676
Syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
RLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26546
GSE178714_5_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3261
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Reticulum trabeculare	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
Frontal Bossing	DisGeNET Gene-Disease Associations	1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228106_0_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10657376-41467_2023_43213_MOESM7_ESM.xlsx-DaNs_EBF1-Unnamed_6_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
Patent Ductus Arteriosus	DisGeNET Gene-Disease Associations	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9364
hexosyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
PMC11485038-384_2024_4744_MOESM1_ESM.xlsx-Sheet3-Supplementary_Table3_Unique_leader_cis-pQTLs_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Small Labia Majora	DisGeNET Gene-Phenotype Associations	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6972
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5675
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5979
4939_MED17_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	2.1239
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_5_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ptosis	DisGeNET Gene-Disease Associations	1.0	null
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
acetylglucosaminyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
Photoreceptor outer segment membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
SHORT syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07286
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ocular hypertelorism	MGI Mouse Phenotype Associations 2023	1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-8_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spade-Like Hand	DisGeNET Gene-Disease Associations	1.0	null
UMUC11	DepMap CRISPR Gene Dependency	1.0	2.9132
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10652340-ACEL-22-e13915-s007.xlsx-FOXJ2-SYMBOL_FOXJ2	Rummagene Transcription Factor Associations 2026	1.0	null
Subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30241
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_HT-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7375
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE71385_1_v_2_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Clitoral Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE197257_0_v_1_gpd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_5_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retinal degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
Fundus Coloboma	DisGeNET Gene-Disease Associations	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7687
Accessory Kidney	DisGeNET Gene-Disease Associations	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.0756
PMC9314343-41467_2022_31892_MOESM8_ESM.xlsx-FigS7d-CTCF_in_promoter_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.917
PMC11522069-439_2024_2703_MOESM2_ESM.xlsx-Table_S3-HsCHD_AR_N_115_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315749
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35279
Anterior Hypopituitarism	DisGeNET Gene-Disease Associations	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Agenesis	DisGeNET Gene-Disease Associations	1.0	null
Diastasis Recti	DisGeNET Gene-Disease Associations	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3746
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.509
Tn Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Low-Set, Posteriorly Rotated Ears	DisGeNET Gene-Phenotype Associations	1.0	null
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.709
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16798
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Downstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0267
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Otopalatodigital syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303627
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brachydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.408
Defective B3GALTL causes PpS	Reactome Pathways 2024	1.0	null
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.512
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135352_6_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2938
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal detachment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_7_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Low Set Ears	DisGeNET Gene-Disease Associations	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXC2_FOXC2	Rummagene Transcription Factor Associations 2026	1.0	null
Tooth bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
Ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
Coloboma Of The Retina	DisGeNET Gene-Disease Associations	1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCEAL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49946
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25136
Microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.341
micropexophagy-specific membrane apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.536
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3292
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.979
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0051
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
Craniosynostosis	DisGeNET Gene-Disease Associations	1.0	null
Intestinal Fistula	DisGeNET Gene-Phenotype Associations	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.561
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.019
TBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09733
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4986
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
Neck Webbing	DisGeNET Gene-Disease Associations	1.0	null
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.654108
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Inherited metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6784
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0462
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.8759
X-linked cone-rod dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2844
GSE173840_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302458
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TE10	DepMap CRISPR Gene Dependency	1.0	3.02347
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.92146
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.47236
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.385
Parental longevity (mother's attained age)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
PMC11459707-12890_2024_3289_MOESM1_ESM.xlsx-Table_S8_MR_results-Supplementary_Table8_The_causal_effect_of_proteins_on_IPF_risk_from_UK_Biobank_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.639
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6546
PMC10362259-BLOODA_ADV-2022-009035-mmc1.pdf-6-TCFL5_TCFL5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
enlarged neurocranium	MGI Mouse Phenotype Associations 2023	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100288_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.7604
Hydrocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
Spondylocostal dysostosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
NAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5844
chr13_31331469_A_G_b38	GTEx eQTL 2025	1.0	3.86137
Popliteal Pterygium Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153757,GSE153758_0_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2165
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8524
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	Reactome Pathways 2024	1.0	null
Widely Spaced Teeth	DisGeNET Gene-Phenotype Associations	1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61712
Facial Hypertrichosis	DisGeNET Gene-Phenotype Associations	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Short Toe	DisGeNET Gene-Phenotype Associations	1.0	null
GSE130690,GSE130692_2_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Orbital cyst	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
DENND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56037
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.7325
PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154961,GSE154963_4_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Alternating esotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
Retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155567_3_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Aniridia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.277
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
CHARGE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2313
Biliary Tract Abnormality	DisGeNET Gene-Phenotype Associations	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
Square Pelvis Bone	DisGeNET Gene-Disease Associations	1.0	null
Proximal Placement Of Thumb	DisGeNET Gene-Phenotype Associations	1.0	null
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebral Ventriculomegaly	DisGeNET Gene-Phenotype Associations	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1333
Chromosome 8q21.11 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
Midgut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
Macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.614
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	3.51462
abnormal neurocranium morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226770_3_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16927
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818