association	dataset	threshold value	standardized value
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898842
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
GATD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03159
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02194
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10435664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89438
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13868
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00719
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85835
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86063
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08402
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_9867_Mut|KD_SRSF2_SRP368113	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.16577
hexestrol-5776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.3192
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6731
FOXP2	ChEA Transcription Factor Targets	1.0	null
glimepiride-4973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_5305_KO_Dnmt1/Dnmt3a/Dnmt3b_SRP101434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.10512
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1743
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23072
Perturb_5550_KO_FBXO11_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.52274
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2074
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39089
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEMA4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22196
blood vessel	GTEx Tissue Gene Expression Profiles	-1.0	-0.951138
BRD-K91297952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33677
Perturb_7739_KD_PCF11_SRP175016	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.06656
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S12-Table_S12_MR_resluts_of_brain_pQTL_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943991
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88119
S-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22277
ELF1	ENCODE Transcription Factor Targets	1.0	null
Perturb_17944_KO_Abcc5_SRP058071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.02471
Perturb_2455_KD_ZNF213_SRP243455	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.09049
SNARE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.503
dorzolamide-3565	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941156
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	159.66
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.835642
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K01237277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69944
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5187
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955631
PMC11659471-41398_2024_3203_MOESM2_ESM.xlsx-Table_SE_9-Table_SE9_Z_scores_comparing_signficant_genes_from_OUD_dataset_Seney_et_al_and_rat_models_of_heroin_and_or_LPS_injection_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1279
BRD-A39407481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07077
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25713
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
VTP-27999	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.471043
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8913_KO_KDM1A_SRP348808	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.12627
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANKRD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45092
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074424
BRD-K86008496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46438
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82721
BRD-A09961470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0822
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ING2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35527
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926684
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A66566298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48512
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39995
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01867
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73215
Medial preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04956
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25234
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85879
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4304
BRD-K72146456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19692
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894203
Perturb_7754_KO_LATS1/LATS2_SRP281854	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.57059
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95228
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74786
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.62765
BRD-K47474571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51169
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37691
A172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
melatonin-6293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3279_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC8299217-mmc4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2464_KD_SETDB1_SRP344480	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.238
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998493
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53066
BRD-K42650945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14572
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RG2833	DeepCoverMOA Drug Mechanisms of Action	1.0	1.64
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24343201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45469
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal dominant nonsyndromic deafness 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
CUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50503
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33414
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54343
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03232
corynanthine-2786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-CA-04-2009(H1N1)_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.82841
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20872
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.943346
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.912724
BRD-K03035008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40488
MCF7_CUDC-907_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00621552
BRD-K68676343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54328
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36338
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16778
HCC1806	CCLE Cell Line Gene Expression Profiles	1.0	1.58793
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98222
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12219
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
ovary	HPA Tissue Gene Expression Profiles	-1.0	-1.006
epitiostanol-7342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF419	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5806
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10475
dexamethasone_homo sapiens_gpl570_gse33135	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PEG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46691
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16998
GSE141624_3_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65184
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06273
BRD-K84241565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60163
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33971
trichostatin A-3979	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
scoulerine-2891	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.17091
ATF2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-K04443775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46104
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952909
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.317
BRD-K13461720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53804
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14753
ZR75_1	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74336
BRD-K34377350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02038
Garland cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900068
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Supplementary_Table_2A_Contrast_ATF4-def_control_vs_HCT116_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53027
PMC7914369-thnov11p3676s2.xls-BPTF-KOvsCtrl-AccID_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88134
LXR-623	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.532
estradiol-5955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AG-013608-5944	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78099
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.869341
BRD-K92479346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00753
DIFI	DepMap CRISPR Gene Dependency	1.0	3.2795
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08216
GSE146074_9_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09871160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68262
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3Q8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20758
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.333317
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.444
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46766
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glandular stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10357_KD_BRD4_SRP093774	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60245
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J7-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-71-8520-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926261
Perturb_7212_KD_CNOT1_SRP099077	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.65081
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19883
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990471
clemizole-7371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H-7-5963	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01453
Perturb_6141_OE_PPP1CA/PPP1R8_SRP118980	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.99882
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898782
Perturb_14809_OE_Ldah_SRP282425	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.0898
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06264
EP300	ENCODE Transcription Factor Targets	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00313
BRD-A21877498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24941
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15342
LHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59996
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49661
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.35623
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52886
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843063
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15018_KO_Sirt6_SRP374172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.79918
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60255752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07769
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55869732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81193
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A54347351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17011
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52702
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40733
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_1323_KD_RBM39_SRP301121	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NRK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
Reticulocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85258
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.940247
HCC1395	DepMap CRISPR Gene Dependency	1.0	4.55368
Perturb_2900_KD_HDAC1_SRP327853	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.08253
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09934
Perturb_2237_KO_Malat1_SRP193997	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.309
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06313
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63713
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1579
hsa-miR-4505	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K92431275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0043
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.41966
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867892
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222911
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943079
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44364
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
alprostadil-4179	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K27824953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7057
Perturb_17570_KD_Tead4_SRP089678	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.0132
SOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27915
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of synaptic transmission, GABAergic	GO Biological Process Annotations 2023	1.0	null
flufenamic acid-316	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
Perturb_16494_KD_RBM39_SRP301121	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.3468
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S11-Table_S11_MR_resluts_of_brain_pQTL_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1603
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07451
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-0.941669
Perturb_15079_KD_Ash1l_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.8263
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP600125	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06007
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69539
chr16_1341220_G_A_b38	GTEx eQTL 2025	1.0	1.90816
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methazolamide-6268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
azathioprine-5627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gemfibrozil-5069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852172
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15159
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
WDR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18842
IL21_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	2.27378
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837823
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14875_KO_H12_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.02193
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1416
butoconazole-5388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852724
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15245
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880759
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93267
aminohippuric acid-6453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EDNRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36238
PELI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58757
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.2977
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093711
BRD-K48813201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65996
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27104
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14095
Perturb_16746_KO_Ly6e_SRP250973	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.94688
BRD-K92011556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60356
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146074_0_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44076
EWSR1_KD_GDS4962_465_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12132610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09971
Temtamy preaxial brachydactyly syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
Penis_Foreskin_Keratinocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.62115
picrotoxinin-4842	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K83095019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52822
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02171
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
fusaric acid-3245	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966969
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12032
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38644
HELA	BioGPS Cell Line Gene Expression Profiles	1.0	1.04842
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42821
trichostatin A-6879	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pons	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.857585
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2109_KD_PRPF31_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.53505
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.451831
trans-Golgi network membrane	GO Cellular Component Annotations 2025	1.0	null
IRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88158
BACH1	ChEA Transcription Factor Targets	1.0	null
dense core granule	GO Cellular Component Annotations 2025	1.0	null
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38686
Primary somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.597
COLO704	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84986
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
BRD-A70167453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0993
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17583
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418808
Perturb_10654_KO_Msi2_SRP201802	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.33095
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trichostatin A-5976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00121
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08445
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25456
BRD-K18074484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11551
Perturb_7220_KO_EED_SRP321650	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_14149_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.5409
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67907
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GRPEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33806
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23696
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15821
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25134
lasalocid-3360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.739277
DMS-53	GDSC Cell Line Gene Expression Profiles	1.0	1.51745
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849146
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84529
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929194
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52623
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24246
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.942868
Bestatin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.778726
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872971
TET2_KO_GDS4287_431_mouse_GMP - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22797
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31768
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68463857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24605
BRD-K47083242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48309
BEN	GDSC Cell Line Gene Expression Profiles	1.0	1.81019
Perturb_8162_KD_SNRNP70_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.0726
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_H3K27me3-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2472
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K89932793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39466
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910469
17597811-SuppTable6	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907571
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.96845
Perturb_12326_KD_CD274_SRP189203	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
trichostatin A-5441	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05129
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.86134
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.127516
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08993
GSE143643,GSE143644_1_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8055_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.2631
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	2.15504
DOV13	DepMap CRISPR Gene Dependency	1.0	5.3337
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225095
HPAFII	CCLE Cell Line Gene Expression Profiles	1.0	1.43218
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00135
octopamine-5469	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_9700_KO_TREX1_SRP355094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855197
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tomatidine-7166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.28101
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69082
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08794
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S15-Table_S15_MR_resluts_of_brain_pQTL_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.004
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CL11	DepMap CRISPR Gene Dependency	1.0	2.98585
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Dacinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00570477
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10789969-crt-2023-577-Supplementary-Table-S2.pdf-1-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
trimipramine-4083	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC3_KO_GDS4886_66_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18732
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98768
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882846
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
piracetam-2861	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904839
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6453
Perturb_11927_KD_SMARCB1_SRP127642	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.16303
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80699
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.95069
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72311
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GDM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.83225
13c4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19508
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40309
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.36938
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993929
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17833
BB65-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63092
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30201
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38039
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949023
Perturb_6290_OE_ZNF165_SRP390251	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.71214
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857335
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
HS229T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.39542
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86525
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.01546
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99554
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910469
ZNF316	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08165
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14785
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.63359
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.08273
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HHV8_72Hour-BEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.97619
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12389
18172295-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19692
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31963
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956019
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39074
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01013
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72455
hsa-miR-518d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K56469794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70055
KRT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23316
Toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
hsa-miR-564	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
TTC9C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25972
Pituitary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03545
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09391
scopolamine N-oxide-6335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_3_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14988_KO_Phf8_SRP093797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.70942
Perturb_9599_KO_Csnk1a1_ERP003394	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K74475430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5328
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Late endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3479
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.915736
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55156
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.892
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57437
Perturb_3299_KO_Bmpr1a_SRP116199	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.11418
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21474
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
BRD-K90127324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54662
GSE166004_1_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52891
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00636
trioxysalen-5736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chloropyrazine-6148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.1699
trichostatin A-4821	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.75891
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRKCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37248
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37681
tuberous sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.689492
Procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.913283
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16675_KO_Nsd2_SRP327089	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.96229
Pharate pupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
secretion	GO Biological Process Annotations 2015	1.0	null
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
triamterene-6010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pindolol-6834	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.98168
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04294
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47033
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.761
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-Overlap-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
UBAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89016
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970784
BRD-K07336866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04907
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.76282
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0421
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981718
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03324
HCC1428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23367
Perturb_8231_KD_PRPF4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.03795
Perturb_7537_KD_RREB1_SRP265233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.31701
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00784
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.31984
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10475
BRD-K23835343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12024
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
apomorphine-2005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04762
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00101
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062651
Perturb_14477_KO_Zfp36l2_SRP310261	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.15549
trichostatin A-4710	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98342
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ifenprodil-5463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05866
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98198
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMWD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49217
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49777
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925159
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IGF1_OE_GDS3484_542_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
endosome membrane	GO Cellular Component Annotations 2025	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.86132
Pancreas-pancreatic delta cell	Tabula Sapiens Gene-Cell Associations	1.0	0.074689
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3285
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6863-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903349
single-organism localization	GO Biological Process Annotations 2015	1.0	null
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23914
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09271653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81324
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927311
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K62935946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3558
ANKRD65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97034
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.83449
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55647
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859943
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.835183
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H2BK120ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299333
KYSE-520	GDSC Cell Line Gene Expression Profiles	-1.0	-2.2446
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861216
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
clebopride-5412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75051
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206158
GSE227137,GSE227139_0_v_1_themis2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
pipenzolate bromide-4484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.25315
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.93126
hsa-miR-3202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.3879
BB-20-UU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258322
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02647
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32999
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962563
Sitaxsentan	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927253
Perturb_6842_KD_RALY_SRP234429	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30014
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053184
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94863
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
modulation of chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13667
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO-824	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48343
hsa-miR-2861	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K10221669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24335
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.852422
ALCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56592
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89438
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.57084
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09696
PHF8	ENCODE Transcription Factor Targets	1.0	null
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07273
disorder	GeneRIF Biological Term Annotations	1.0	null
GSE211286_1_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97811
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.977206
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.79338
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03974
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21269
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
Endoplasmic reticulum tubular network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.698
BRD-K60558601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38817
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33563
berberine-6791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72774661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63063
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.18111
oxetacaine-1484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19384
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20281
Perturb_8899_KD_IQGAP3_SRP359044	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.758
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1307	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260164
abnormal behavioral response to xenobiotic	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_7463_KD_RBM17_SRP126064	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.5229
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974023
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
sulfaguanidine-4839	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gastric cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.324
etodolac-2254	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79897
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12659
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.855744
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60452
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC3470785-NIHMS377161-supplement-14.pdf-213-NR3C1_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06401
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.871707
FA-80-DR66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246408
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.86434
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91092
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00526
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48645
PMC5390115-mmc7.xlsx-DE_Lists-H1-ECs_Experiment_2_H1-EC2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-588	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
trichostatin A-5987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81023
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1990	DepMap CRISPR Gene Dependency	1.0	3.27266
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
isoniazid-2246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11174
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042652
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48352
Perturb_2717_KO_TET1_SRP110516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.35557
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.28093
NCIH810	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76206
recycling endosome membrane	GO Cellular Component Annotations 2023	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06513
Perturb_12239_KO_ZMYND8_SRP130942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.15469
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.08279
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.519655
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65202
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33488
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23871
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4747
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.920583
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5048
Perturb_16727_KO_Mbd2_SRP326773	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.81445
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76277
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0313
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.1043
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GMEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49397
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18524
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883663
CIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99153
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44158
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.24372
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
skimmianine-2504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HPAC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63582
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28079
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51685
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.177301
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM253	DepMap CRISPR Gene Dependency	1.0	2.85674
BRD-K16251850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79964
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.38774
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906037
doxorubicin_homo sapiens_gpl550_gds845	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.534
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Unnamed_1_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872083
brain	GTEx Tissue Gene Expression Profiles	1.0	1.09306
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25247
Perturb_7910_KO_CLP1_SRP367036	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.9836
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.97682
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03537
CHEK1_knockdown_136_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.30975
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41153
NB6	DepMap CRISPR Gene Dependency	1.0	4.09705
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
bemegride-6668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92312
Perturb_1730_KD_Brd4_SRP074419	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K69879051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32915
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270447
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881983
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.992641
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33907
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910469
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855845
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041492
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chlorogenic acid-3282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065972
recycling endosome membrane	GO Cellular Component Annotations 2025	1.0	null
Perturb_17249_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.09402
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71623
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20759
BRD-K93611325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11802
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98192
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Pentoxifylline_AsPC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00835839
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2803
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.999868
496100513_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04147
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.30741
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216343
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
josamycin-1534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19792
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87925
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918917
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905264
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.64351
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922536
Nectary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.255
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2772
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3071
scriptaid-6901	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_5310_KD_CDK11_SRP172707	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.7616
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HuO9	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56331
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48167
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2762_KD_BRG1_SRP077334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.63079
KCTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59355
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15081
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.44296
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100102_4_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196699_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11138
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2023	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278848
CADOES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86334
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.98916
acemetacin-6361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5857
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO668	CCLE Cell Line Gene Expression Profiles	1.0	2.16356
HEK-293FT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.902645
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56835
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33987
SW403	CCLE Cell Line Gene CNV Profiles	1.0	1.47464
LXF-289	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59183
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27722
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911909
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDE7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91809
CRCGN015_MCF10A.TP53.M_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38115
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23265
NCI-H747	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842198
lisuride-6682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.916947
GSE151782_3_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77320034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3648
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F4	ChEA Transcription Factor Targets	1.0	null
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10193
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEMA3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90969
SW837	GDSC Cell Line Gene Expression Profiles	1.0	2.58401
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36036
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.56418
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15071
ZNF384	ENCODE Transcription Factor Targets	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
Perturb_6717_KO_DNMT1a/DNMT3b_SRP098688	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_9893_KD_SSRP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.37816
IGFLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7619
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.890538
progesterone-4992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16913
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67304
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30635
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	3.56478
late endosome	GO Cellular Component Annotations 2025	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110178_4_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857308
mRNA_ELF1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69025
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10475
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60755
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_2466_KD_NDP52_SRP345458	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.38162
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	159.865
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910469
corbadrine-7208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5187
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175146
Tepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.347
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.47052
RNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93414
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03368
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905424
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11871
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74269
vorinostat-6939	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3610_KO_BCL7B_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.49167
Rhomboid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
Golgi apparatus subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3934
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323839
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05381
SUZ12	ChEA Transcription Factor Targets	1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6617
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEP170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03343
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02098
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35459
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.4328
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94669
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.87
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47997
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1826
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.997868
MCF7_Trichostatin A_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00740224
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.17713
NCIH28	DepMap CRISPR Gene Dependency	1.0	3.33239
capsaicin-3372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.344079
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17556
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13821
Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15349_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.8548
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55003
CCDC153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52988
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3290_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K17412949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82037
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949082
hsa-miR-4638-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MAFK	ENCODE Transcription Factor Targets	1.0	null
Cortical endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-OVOL2_OVOL2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91821
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Floral primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.601
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A37796306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73869
modulation of chemical synaptic transmission	SynGO Synaptic Gene Annotations	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75843
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07458
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3118	DepMap CRISPR Gene Dependency	1.0	2.20654
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.08237
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06313
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2741
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103391
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30192
BRD-K97224540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81252
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.99351
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17836
HDAC3_KO_GDS4886_29_mouse_heart - 6 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00921
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44305
trichostatin A-6579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067726
ERBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07256
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914693
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66537
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54239
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841769
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235457
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.879013
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.798
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877427
Perturb_1094_KO_ATXN1L_SRP230198	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.14523
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79929
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33987
BRD-K45153693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47083
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12152
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02673
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9456
mantle zone of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18481
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18419
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00536
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29034
TUFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87046
MAZ	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4246_KD_GATA3_SRP372594	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.42984
EFR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53318
vorinostat-5217	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68558540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0283
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76827
CEBPD	ENCODE Transcription Factor Targets	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19248
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27159
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84468
MCF7_Quisinostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0069521
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7899452-media-4.xlsx-Early_Resp_FOXJ1_high_Ciliated-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SQ-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92017
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07659
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36805
thalidomide-2095	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30569
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34518
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AT-A5NU-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.01002
BRD-K45190659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3462
finger	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.397979
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12856
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hand	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.397222
BRD-K26766324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11477
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5042
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.454895
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PF-00562151-00-5954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16421840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04836
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66235
NCI-H1975	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75784
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85478
NEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24526
15980968-Table3b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896722
BRD-K45519638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41895
Perturb_7705_KD_YTHDF1/YTHDF2/YTHDF3_SRP214946	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.74426
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911909
BRD-K97183783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43077
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945184
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.76337
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927611
GSE140284_0_v_1_hhex_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	2.59987
BRD-K83270526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50324
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.900813
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.08847
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20728
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318971
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050301
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85678
dense core granule maturation	GO Biological Process Annotations 2025	1.0	null
OGFOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53453
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05578
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18488
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17242
SUPT3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92286
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80112
ERRalpha_Deficiency_GDS2727_646_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF525	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63219
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.44068
BRD-K13782363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31081
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64979
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30107
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91647
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05059
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0167
AC-41-IB85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201143
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903022
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224573
cloperastine-4732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.84526
HCC202	DepMap CRISPR Gene Dependency	1.0	7.40562
trichostatin A-6434	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
Perturb_2148_OE_RKIP_SRP189735	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.20815
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.54506
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trans-Golgi network membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2276
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852172
secretory granule maturation	GO Biological Process Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
felbinac-5700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890612
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17408_KO_Rag2_SRP092590	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.18547
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
Presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.073
Prestwick-1084-6767	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SFT2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25539
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90431
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53657
ivermectin-2213	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74635
Root apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
cinchonine-2789	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89949
CALU6	DepMap CRISPR Gene Dependency	1.0	2.24505
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04431
estropipate-6068	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60705
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53897
GSE146074_1_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CFPAC1	CCLE Cell Line Gene Expression Profiles	1.0	1.50504
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
quipazine-1789	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6420_KD_SPRY4IT1_SRP347515	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.74645
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867557
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10305
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.971483
Erythromycin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.47
chr16_1344429_C_T_b38	GTEx eQTL 2025	1.0	2.38652
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05932
RFX5	ENCODE Transcription Factor Targets	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2896
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56334
BRD-K81995936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05494
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36837
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24431
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47849061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14972
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13896
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860807
decamethonium bromide-4174	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Colorectaladenocarcinoma	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15777
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.04133
retrograde transport, endosome to Golgi	GO Biological Process Annotations 2023	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01895
estradiol-5960	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K22940496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62654
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09989
TET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37345
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18772
GSE229973_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15982
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22399
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3709
MTA3	ENCODE Transcription Factor Targets	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053089
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93104
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859573
BRD-K90205159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46084
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986476
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.865303
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-5935	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
late endosome membrane	GO Cellular Component Annotations 2023	1.0	null
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55533
TAF1	ENCODE Transcription Factor Targets	1.0	null
isradipine-6347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.495592
HSC-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.06778
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843063
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.7142
MTFR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39872
PMC7899452-media-4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10997
Perturb_4717_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KK-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RVX-208	DeepCoverMOA Drug Mechanisms of Action	1.0	1.03
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S18-Table_S18_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-002_4H_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0536
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	1.43766
Endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LB1047-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66247
dopaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.545739
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10106
BRD-K64451677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21825
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Perturb_6324_KD_AdipoR1_SRP377446	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.96077
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13425
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40354
Perturb_6572_KO_Gls_SRP338093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.5846
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07525
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075774
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K87000197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43994
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34452
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19512
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08044
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37027
Prestwick-559-2877	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.01104
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19004
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trichostatin A-3332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99539
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38062
PA-80-RV09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242627
PMC9374162-mmc4.xls-KD_gene_list_heatmap_235_genes-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CORL279	DepMap CRISPR Gene Dependency	1.0	2.87393
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
DU-4475	GDSC Cell Line Gene Expression Profiles	1.0	2.096
hsa-miR-3126-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SW1990	GDSC Cell Line Gene Expression Profiles	1.0	2.54716
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.47555
Perturb_16594_KO_Xbp1_SRP057879	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.16363
cloperastine-3710	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896383
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01046
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Transcriptional misregulation in cancer	KEGG Pathways 2026	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.223165
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.05684
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36059
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.07002
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of PHyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06673
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36129
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4008
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43375
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857047
GSE129772_2_v_1_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0614
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4866_KO_HES1_ERP110708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.961498
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trichostatin A-3868	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39671
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02982
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trans-Golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866267
loracarbef-5073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BCORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52342
Mammalian uncoordinated homology 13, subgroup, domain 2	InterPro Predicted Protein Domain Annotations	1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.84593
Hatching gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
atropine oxide-6812	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trichostatin A-3395	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38492
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862877
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15904
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.05352
Perturb_6694_KD_PLKO_SRP078060	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.89404
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ALKBH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00212
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11477
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.960922
Perturb_743_KD_RASSF2_SRP233387	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44562
BACH1	ENCODE Transcription Factor Targets	1.0	null
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	2.8825
inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16744
Perturb_11736_OE_KLF5_SRP091857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_3278_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCD-841-CoN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995138
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DHX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3872
chr16_1330702_C_T_b38	GTEx eQTL 2025	1.0	4.00729
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
Perturb_11038_KO_Synm_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.55398
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07434
Perinuclear endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
C19orf53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02228
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	1.0	null
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.60688
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68078
FASLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0428
TULP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04558
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28664
MCM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05929
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43513
SK-LMS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NB-598	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
ZNF732	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20194
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
tracazolate-4964	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.82966
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36488
positive regulation of neurotransmitter transport	GO Biological Process Annotations 2025	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28021
LP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
late endosome membrane	GO Cellular Component Annotations 2025	1.0	null
TATDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09845
Perturb_14676_KO_Jazf1_SRP237285	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.17417
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31755
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848178
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04212
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
cinchonidine-2772	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01014
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neuronal dense core vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.899
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05489
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24064
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0715
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01091
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833011
KMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27598
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32577
RAD21	ENCODE Transcription Factor Targets	1.0	null
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77056
PMC11732233-mmc1.pdf-336-TCF3_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01779
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26336
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3687_KD_RARRES2_SRP287866	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.127
BRD-K46458719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18419
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
Dsl1/NZR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.577
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1045
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.05173
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0895
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.56872
positive regulation of synaptic transmission	GO Biological Process Annotations 2025	1.0	null
Autosomal recessive nonsyndromic deafness 79	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02146
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ENSG_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94514173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02472
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69396470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0661
Lung adenocarcinoma_LUAD_TCGA-55-8511-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3324_KO_Tkt_SRP364774	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.85504
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RARB-27405468-CHIP-SEQ-BRAIN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE233441_1_v_0_tnnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A12725272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14069
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13464
Perturb_5562_KO_MTSS1_SRP266832	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.73852
BRD-K95338817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01788
regulation of neurotransmitter secretion	GO Biological Process Annotations 2025	1.0	null
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874451
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.12848
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.838936
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3166	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE183316,GSE183317_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73797
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42114
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00403
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81978
LIVF001-002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41545
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
PMC11237666-spectrum.03516-23-s0004.xlsx-Early_Resp_FOXJ1_high_Ciliated-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69523
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9993
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57657
HDAC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62977
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A97608543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43443
PMC12659123-12864_2025_12285_MOESM12_ESM.xlsx-Table_S12-Table_S12_Differentially_expressed_genes_after_SPI1_knockdown_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44042
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31487
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05544
recycling endosome	GO Cellular Component Annotations 2025	1.0	null
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42829
aminocaproic acid-6501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.801
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830825
PDE10A_KO_GSE40377_581_mouse_Striatum and hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15556
OVCAR5	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
BL2158 (USP34)	NURSA Protein Complexes	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.07828
vincamine-3865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846081
Perturb_8059_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.60921
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33058
tretinoin-1636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP64	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50001
Perturb_2317_KD_PRPF31_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.30763
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO3-_-_vs_FOXO3_hMyotubes_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
fenoprofen-4274	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Quisinostat	DeepCoverMOA Drug Mechanisms of Action	1.0	3.38
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07642
CHEMBL569227	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.58
hsa-miR-4651	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.3364
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19102
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157911_1_v_0_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852356
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61882
SNU869	CCLE Cell Line Gene Expression Profiles	1.0	1.50068
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68809
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72201
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34811
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_11690_KO_METTL14_SRP237514	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.44996
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_2548_KO_MLL3_SRP163132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.26364
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.73605
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24043
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32254
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40249
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18906
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06776
15888489-Table1	GeneSigDB Published Gene Signatures	1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7452
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949849
Perturb_17520_KO_Cns2_SRP041655	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.8069
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15944
DKMG	DepMap CRISPR Gene Dependency	1.0	3.88927
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.860077
subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08766
BRD-K38345640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16667
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.971483
Posterior amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836432
BRD-K11093795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40118
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1419
RPS6KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08454
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trichostatin A-4388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79012
Egg chorion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.758
LHX1_KO_GDS2748_298_mouse_embryonic renal vesicles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Exocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219501
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96818
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	-1.0	-0.889621
BRD-K97472167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34892
BL308 (SMC1A)	NURSA Protein Complexes	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_3276_KD_RORA_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
LARP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94568
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67645
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75825
NTPCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07919
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5284
trimethobenzamide-4180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
benzodiazepine	GeneRIF Biological Term Annotations	1.0	null
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86775
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20651
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.868433
Alpha thalassemia-intellectual disability syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.846
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22456
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08996
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907752
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Asthma, allergic_Bronchial epithelium_GSE3004	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43041
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.955138
almotriptan	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05174
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07226
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22099
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062602
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18015
GARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.349
Rectum adenocarcinoma_READ_TCGA-AH-6644-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mammalian uncoordinated homology 13, domain 2	InterPro Predicted Protein Domain Annotations	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924666
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957901
Petroclival meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	1.83794
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06304
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074173
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11790_KO_Cd109_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.45639
vigabatrin-5415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3441
BRD-K16705434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55588
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5307_KO_Dnmt1/Dnmt3a/Dnmt3b_SRP101434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.1778
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.606
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890649
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41457
Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior fossa meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.94773
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.07093
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18529
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053088
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23871
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00408
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48185
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.00505
proglumide-3780	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44695
Perturb_7547_KO_CNOT1_SRP282906	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.59274
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx Skin 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	5.0402
valproic acid-345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO 849	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.919605
RA-86-LI22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241435
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42262
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.992217
ovary_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13273
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28291
GSE211286_7_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9290241-13058_2022_1547_MOESM2_ESM.xlsx-Foglio1-Supplementary_Table_S1_Differentially_expressed_transcripts_in_common_between_EPZ-_and_MI-2-treated_MCF-7_cells_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14025
alpha thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.678701
17597811-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89077
Perturb_14885_KO_H12_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.6873
indapamide-2361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_13713_KO_ASXL2_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.46791
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58806
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17606
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10667
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of insulin secretion involved in cellular response to glucose stimulus	GO Biological Process Annotations 2025	1.0	null
FU-OV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_6463_OE_NFAT1_SRP173011	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	1.0	0.890699
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850554
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48092898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28307
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19886
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10318747-12864_2023_9472_MOESM2_ESM.xlsx-OCI-AML3_3h_vs_Control-Unnamed_1_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922358
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38456
KYO1	DepMap CRISPR Gene Dependency	1.0	4.66834
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915859
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3545
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
SLC39A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42142
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34435
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826409
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03208
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38572
Perturb_3596_KO_DELE1_SRP218218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.97435
establishment of localization	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894133
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07812
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Amnioserosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_36_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
vorinostat-1000	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Familial lipase maturation factor 1 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
midodrine-6804	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60687
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16432
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38766433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22934
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_14_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15947051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22828
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37036
2-Cl-IB-MECA	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
abnormal response to novelty	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K25284184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44602
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.123
PMC10657376-41467_2023_43213_MOESM7_ESM.xlsx-DaNs_EBF1-Unnamed_6_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62051
cefazolin-3426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15183
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852172
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
phthalylsulfathiazole-3371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
COLO679	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84658
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3896_KD_VprBP_SRP328755	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
inner CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04403
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44360367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28546
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Somatosensory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59617
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4362
MTURN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40492
etifenin-2838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HS839T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63952
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6035
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52799
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55513
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05045
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5034-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Flight muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1909	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
dexamethasone_mus musculus_gpl5137_gse10900	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	0.886396
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61845
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.936398
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
ACSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47254
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.646004
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897546
MTHFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24669
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11744
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962605
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
secalciferol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20038
Perturb_9886_KD_ABCF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.36609
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257032
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34164
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84736
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24043
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_3241_OE_IK6_SRP136156	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.2616
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58068
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.56965
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85123
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12281
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7062
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05605
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01655
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	2.98093
BRD-K87010860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11783
iobenguane-2878	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UO31	BioGPS Cell Line Gene Expression Profiles	1.0	0.849873
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8316
ZNF143	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06313
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
BRD-K51572611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48594
positive regulation of secretion by cell	GO Biological Process Annotations 2025	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1287
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73729
connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048743
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63028
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41754
hsa-miR-759	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47017
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.9203
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.1229
neurological	GAD High Level Gene-Disease Associations	1.0	0.293278
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96907
GSE210150_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218500_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13732_KD_PRMT5_SRP324755	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.46173
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45563
EMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2395
PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Unnamed_2_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cefotaxime-2235	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
convolamine-5876	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ribociclib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.63
Perturb_9484_KO_Tcf7/Lef1_SRP251706	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06491
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Climbing fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
PMC11474168-ccr-23-1242_supplementary_table_s4_suppst4.xlsx-AR_tumors_genes-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04218
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06446
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21288
Perturb_7363_OE_RBFOX1_SRP307800	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.9235
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83396
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08084
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38698
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05833
Perturb_7873_KD_FSCN1_SRP258738	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.88405
H4C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27793
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202947
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACADVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14868
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964649
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07861364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5707
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TSC1_Deficiency_GDS4572_346_mouse_Naive CD4  T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K89278382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64911
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.710559
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28972
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.728992
PLHC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC812	CCLE Cell Line Gene Expression Profiles	1.0	2.18246
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16747
Perturb_13940_KD_SETD8_SRP075406	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34242
Lung adenocarcinoma_LUAD_TCGA-50-8457-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7161_KD_CD81_SRP385887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.46596
18537972-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85053
BRD-K16231990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05605
Perturb_14046_KO_Bach2_SRP399450	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.45932
Perturb_17361_Mut_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.0535
CHD2	ENCODE Transcription Factor Targets	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.964007
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34048
BRCA1	ENCODE Transcription Factor Targets	1.0	null
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46818
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CP-690334-01-3823	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852172
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41114
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10809
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
retrorsine-4946	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11237666-spectrum.03516-23-s0004.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27903
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95191
hsa-miR-3922-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.425514
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910469
GSE226091,GSE226092_3_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Reticulocyte fraction of red cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55135464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3524
BRD-K02078126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57331
BRD-K85568664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06651
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29867
BRD-K62102480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42635
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71032
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992014
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1889
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148200_0_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29043
Perturb_960_KO_Psmc4_SRP173487	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.6487
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971778
GSE217201_1_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77697725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13756
Perturb_7541_KO_NSUN6_SRP273753	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.02439
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13266
Trolox C-6007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TTC31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19004
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01696
cytosolic transport	GO Biological Process Annotations 2025	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_702_KD_SETDB1_SRP116954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.93212
positive regulation of insulin secretion	GO Biological Process Annotations 2023	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1879
Masseter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
Perturb_14840_KD_GCM1_SRP358680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.25504
UPMD1	DepMap CRISPR Gene Dependency	1.0	2.02835
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10278
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64247
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05624
NU7441	DeepCoverMOA Drug Mechanisms of Action	1.0	1.45
Perturb_5810_OE_Mnx1_SRP373412	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.35776
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40652
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4940_KO_Cbfa2t2_SRP061948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.98751
496100652_PCx_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50349
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36219
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04116560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00587
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65854
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.111
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA2_FOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01008
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A6UC-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849564
Perturb_12635_KD_SPANX_SRP236602	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.38991
JUND	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.55679
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09499
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A58937872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30948
Perturb_16994_KO_Elp3_ERP121703	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.3048
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_3288_KD_RORA_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_7384_KO|KD_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
tiaprofenic acid-4171	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07911
BRD-K66734120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08214
hsa-miR-4722-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dexamethasone-123	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45009
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.997687
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24977393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5311
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01629
gramine-3999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trichostatin A-4770	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.15892
pentetrazol-2255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3873_KD_OR10A5_SRP333146	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.80428
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of insulin secretion involved in cellular response to glucose stimulus	GO Biological Process Annotations 2023	1.0	null
HCC1897	CCLE Cell Line Gene Expression Profiles	1.0	2.83262
JQ-1	DeepCoverMOA Drug Mechanisms of Action	1.0	1.33
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09828
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0154
NH-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_5809_OE_Mnx1_SRP373412	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.1236
RTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09864
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976235
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965101
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7305
Primary somatosensory area, nose, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93352
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1611
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19669
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06635
solanine-2808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
trans-Golgi network	GO Cellular Component Annotations 2025	1.0	null
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.98132
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anabasine-2512	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
trichostatin A-6993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976871
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15878
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4308	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985235
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.96374
pioglitazone_mus musculus_gpl1261_gds4413	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL8109 (RAD54L2)	NURSA Protein Complexes	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
DDX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23791
sulfamonomethoxine-5843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13891
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0892
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857335
thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.354499
fosfosal-3336	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82088
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_14048_KD_TXNIP_SRP394013	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.63897
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.171
HCT15	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.42908
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03433
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2814	CCLE Cell Line Gene Expression Profiles	1.0	1.64611
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886183
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09815
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.53839
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19273
nadide-6091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K15907840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80256
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900794
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64455
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.565993
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_SUZ12-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.5037
Senescence_frontal cortex_GSE1572	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.66909
GSE134700_0_v_4_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S6.xlsx-EMP_CREB_Targets-symbol_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49303291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32046
RHJT	DepMap CRISPR Gene Dependency	1.0	2.40733
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843955
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
use	GeneRIF Biological Term Annotations	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09153
buflomedil-4840	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.488452
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72375
SCS214	DepMap CRISPR Gene Dependency	1.0	2.63983
BRD-A84923154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06861
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49276
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
AD-51-FB60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309042
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1703
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60176
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.16405
TGIF2LX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0459
TCF12	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.9899
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62312
Lateral dorsal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0316
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.920605
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845206
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16544
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906764
BL1113 (CENPH)	NURSA Protein Complexes	1.0	null
PMC11116544-41698_2024_606_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_4_Significantly_differentially_expressed_genes_between_TCGA-HNSC_patients_carrying_amplified_MYC_and_wild-type_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00029
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15877
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14122
specifically	GeneRIF Biological Term Annotations	1.0	null
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66032
Perturb_4836_KO_Chd8_SRP306703	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.84242
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28367
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-1659	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenformin-4283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71718
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K98153780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86108
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24536
SYK_KD_GDS3609_441_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.937187
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01601
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44855
flupentixol-6708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_16424_OE_AUF1_SRP224925	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.284
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841623
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06072
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47843
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26763
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-86621-7548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Moxonidine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42281
BRD-K57626519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51411
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
BRD-K48308783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6131
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0853
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13266
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4647
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51827
GLIS3_KO_GDS3812_500_mouse_Embryonic pancreas at E15.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
gabapentin-5875	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05509844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16225
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828769
localization	GO Biological Process Annotations 2015	1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	4.13446
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Stroke	dbGAP Gene-Trait Associations	1.0	0.714946
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843063
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
sulfamethizole-6272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of neurotransmitter secretion	GO Biological Process Annotations 2025	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886671
Perturb_14554_OE_SIRT4_SRP371292	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
chlorpromazine-1642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3169_KD_CYP2J2_SRP220503	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.27938
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62509
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65901
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50691
Perturb_9894_KD_STAU1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43283
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80757
short-rib thoracic dysplasia 9 with or without polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.702
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.96292
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23296
BRD-K01817716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36772
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SEC31B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49317
ERCC6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55388
BRD-K91277001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03596
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10525
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pheniramine-4130	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13352
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418723
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56697
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2-23625967-PFSK-1 AND SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K13309514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85321
BRD-K22384464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21951
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862074
anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47747
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76441
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48492
canrenoic acid-2228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0482
BRD-K48299239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44493
ELK1	ENCODE Transcription Factor Targets	1.0	null
GSE235066_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84077
BRD-A17635048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31368
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10525
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBC1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23705
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30784
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992664
Primary somatosensory area, trunk, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07667
Perturb_28_OE_Smad1_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.24564
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33818
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.49004
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31942
esculin-3390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92344227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0366
BRD-K31952722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51053
Oxyphilic adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070385
Trophoblast giant cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
Large_Intestine-b cell	Tabula Sapiens Gene-Cell Associations	1.0	0.355078
Renal oncocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
BECKER	CCLE Cell Line Gene CNV Profiles	1.0	1.46653
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10654
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.972668
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.60008
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.00454
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83676
regulation of synaptic transmission, GABAergic	GO Biological Process Annotations 2025	1.0	null
ACBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00683
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96907
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1749
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.811901
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.98579
STL304557	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.06502
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
Perturb_15083_KD_Nsd1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.8378
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183316,GSE183317_3_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2197
BRD-A59995060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64628
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16915521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82367
GTEX-XYKS-1226-SM-4BRVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06064
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
isosorbide-3720	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05813
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209371
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30027
Perturb_7558_Mut_ASXL1_SRP305063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.32789
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68051
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916124
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10589
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06805
RUNX3	ENCODE Transcription Factor Targets	1.0	null
trichostatin A-1014	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	3.24225
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.24511
triflupromazine-7466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tolazoline-1500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0461
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29847
Psychomotor Performance	HuGE Navigator Gene-Phenotype Associations	1.0	null
CGAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57644
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13369
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41682
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SK-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
salivary gland	HPA Tissue Protein Expression Profiles	1.0	0.971483
SubthalamicNucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.07773
mesalazine-124	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pseudopelletierine-7184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KYSE-150	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61717
BRD-K41322154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11045
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
B4GALT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60826
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nifenazone-7314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46002
Posterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vorinostat-5580	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAPK14_knockout_13_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.81719
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.857081
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16419_Mut_Gli2_SRP154383	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.58152
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982633
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2-23625967-PFSK-1-AND-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86443
hsa-miR-3176	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
alcuronium chloride-4409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K52406139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02336
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05233
BRD-K55855103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31353
Perturb_4863_KD_BAF47_SRP188516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.49698
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20414
Spongiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.555
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09133
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13667
trichostatin A-5017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PF-00539745-00-5939	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3689
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TC-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FASTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20835
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38134
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.575
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.08348
late endosome	GO Cellular Component Annotations 2023	1.0	null
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0436
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17673
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37267
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63851
C2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.422634
Perturb_6260_KD_NDP_SRP188348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
COX5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50529
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.435129
dicoumarol-4323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29914
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5257
Perturb_10356_KD_BRD4_SRP093774	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3785
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98477
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04522
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57985
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Supplementary_Table_2C_Contrast_ATF4-def_DMSO_8h_vs_HCT116_DMSO_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21336
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70566
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904509
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Munc13 homology 1	InterPro Predicted Protein Domain Annotations	1.0	null
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29381
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44695
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.6128
apigenin-3257	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09622
CUX1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988101
mafenide-2287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100217_1_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47509
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82946
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.502
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09722
KP-N-RT-BM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.40785
GSE120595_0_v_1_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45503
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08445
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-5594	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66937
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31586
hsa-miR-4480	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051753
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Panobinostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00605181
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Prestwick-692-4424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05977
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.1845
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.44941
FOXA2	ENCODE Transcription Factor Targets	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70511
KYSE30	CCLE Cell Line Gene Expression Profiles	1.0	1.57554
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23903
calcium ion binding	GO Molecular Function Annotations 2025	1.0	null
AIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37451
BRD-A80035237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23954
BRD-K25256659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10474
hsa-miR-362-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBXO31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23678
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21719
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96321
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67142
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL2388 (CUL4A)	NURSA Protein Complexes	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DL-thiorphan-2752	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215948
Primary somatosensory area, unassigned, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27354
Aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
DYNLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86144
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00347
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965009
midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.924623
increased anxiety-related response	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
imidurea-5062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Recycling endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Perturb_2825_OE_AKT1_SRP064353	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.3277
Perturb_2980_KD_Mbnl1/Mbnl2_SRP057123	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.99558
diprophylline-5482	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTNNB1	ChEA Transcription Factor Targets	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.782639
PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1087_KD_TBK1_SRP371732	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.58479
Perturb_3521_KD_FACT_SRP328843	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.05335
BRD-K69087429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98273
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K66282601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96703
Perturb_6480_KD_SNRPB_ERP011528	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC8567035-CTM2-11-e578-s001.xlsx-transcription_misregulation-RUNX1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.91571
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979419
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01081
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75574
HUH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83566
KASUMI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74421
Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11716_KD_GATAD2A_SRP194625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.82977
sulfamerazine-4740	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83327
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2921
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.95427
Perturb_8057_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5608
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55713
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901953
CDCA7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61215
17555561-Table1	GeneSigDB Published Gene Signatures	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03433
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09137
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.18906
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.90377
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166768
BRD-K37592272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39835
BRD-K37527826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09083
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7555_KD_SP1_SRP303813	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.78085
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8718
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275333
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.4868
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09176
BML-277	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.77
(-)-MK-801-6657	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77445233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25617
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30419
biological regulation	GO Biological Process Annotations 2015	1.0	null
cyclobenzaprine-3268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85365
16109776-TableS1	GeneSigDB Published Gene Signatures	1.0	null
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19963
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sickle Cell Anemia_Endothelial cell_GSE9877	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.62971
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86911
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7697_KD_HIF1A_SRP286039	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.6624
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
repaglinide-3558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07491
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48433
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40857
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Spitzoid melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
TCF3	ENCODE Transcription Factor Targets	1.0	null
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
chr16_1324817_A_G_b38	GTEx eQTL 2025	1.0	2.70007
Parallel fiber to Purkinje cell synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9088_KD_SUPT16H_SRP106869	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.76939
tolfenamic acid-2120	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A875-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKNOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48319
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9681
KRAS.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92719
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15789_KO_Camk2d_SRP281889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.5809
SYCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43826
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.99997
SARS-CoV MA15_Day4-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.55513
Perturb_8916_KO_KDM1A2a_SRP348808	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.0189
CHEMBL1643306	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.66
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.675982
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76351135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38635
RFX1	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Roflumilast	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04085
BRD-K07870648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43176
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475648
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1507
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.90987
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936531
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33945
retrograde transport, endosome to Golgi	GO Biological Process Annotations 2025	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041294
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56796
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-2.26262
SNB19	BioGPS Cell Line Gene Expression Profiles	1.0	1.09367
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24754
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
ARHGEF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24906
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63733
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
recycling endosome	GO Cellular Component Annotations 2023	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7385_KO|KD_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_6824_KO_DNMT1a/DNMT3b_SRP098688	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_1_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51826
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCI-34051	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
Perturb_2329_KD_SF3B5_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.46421
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.6932
Perturb_2294_KD_DDX5_SRP139509	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34485
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2365
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39704
Diazinon	CTD Gene-Chemical Interactions	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.063
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.856711
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
BRD-K84815485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18441
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
vincamine-4341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3947_KD_RNF6_SRP126561	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.2459
layer 6 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11562
trichostatin A-332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XF-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vorinostat	DeepCoverMOA Drug Mechanisms of Action	1.0	3.41
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09073
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936531
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90904
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2395
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16852474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17332
GSE237040_6_v_3_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
chloroxylenol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23928
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
High light scatter reticulocyte percentage of red cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cytosolic transport	GO Biological Process Annotations 2023	1.0	null
ARMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20539
secretion by cell	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17379
hsa-miR-526a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HERC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19643
Perturb_11723_KO_Eomes_SRP187979	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0237
Aerial root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOV10L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36432
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43657
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843063
positive regulation of insulin secretion involved in cellular response to glucose stimulus	GO Biological Process Annotations 2023	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Benzodiazepine Abuse	DisGeNET Gene-Phenotype Associations	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1611
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18199
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935184
early endosome membrane	GO Cellular Component Annotations 2025	1.0	null
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.15855
cellular process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47S-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_2_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NH12	DepMap CRISPR Gene Dependency	1.0	4.11975
SDCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53021
Bract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38346
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6626
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.953974
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16382
KARPAS-1106P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_2318_KD_PRPF8_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.27329
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18505
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05069
upper basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04457
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT1376	DepMap CRISPR Gene Dependency	1.0	2.06787
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.731
BRD-K34519525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17551
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of neurotransmitter transport	GO Biological Process Annotations 2023	1.0	null
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52854
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02484
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14782
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydroxyprogesterone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23681
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07667
MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7825356-8844261.f3.docx-55-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.326281
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94728263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11153
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_9864_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.55013
Perturb_15035_KD_Ctcflos_SRP311201	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.45117
(-)-isoprenaline-3571	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43991
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
metal ion binding	GO Molecular Function Annotations 2025	1.0	null
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0789
BRD-K87158974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74938
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12212
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11394
CDK4_knockdown_143_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.76115
EWS502	DepMap CRISPR Gene Dependency	1.0	2.59845
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4	DepMap CRISPR Gene Dependency	1.0	2.59568
MPHOSPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00714
GSE105170,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1412
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3651
Periventricular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11249
KLF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2781
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837303
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40876
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0316
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66313
TBP	ENCODE Transcription Factor Targets	1.0	null
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35035
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24485
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904639
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04922
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27529
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060449
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-5260	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36869
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84426
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251794
HCC1833	CCLE Cell Line Gene Expression Profiles	1.0	1.65322
PABPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05356
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266915
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A6GG-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plicamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27529
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17724462-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843364
nifuroxazide-4835	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55008
CRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83047
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CNTROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44938
BALL-1	GDSC Cell Line Gene Expression Profiles	1.0	2.10534
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02181
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79252
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.28698
layer 6 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17173
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950374
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10484
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5745
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843063
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74806
LU-65	GDSC Cell Line Gene Expression Profiles	1.0	1.55267
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
benzocaine-4808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54079231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27708
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11319
trichostatin A-4112	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-485-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.521375
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48915
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02384
FABP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01692
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55063
E2F6	JASPAR Predicted Transcription Factor Targets	1.0	null
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49792
transport	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.40311
Perturb_9233_Mut_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.37612
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32603
bucladesine-3483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VU0152100	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76714
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AKAP17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93657
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927335
positive regulation of insulin secretion	GO Biological Process Annotations 2025	1.0	null
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22218
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988785
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12141
trichostatin A-7043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826043
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11545
BRD-K25236390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25708
Perturb_9600_KO_Csnk1a1|Trp_ERP003394	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43622
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16818
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE211215_1_v_0_akr1b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tetraethylenepentamine-574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837785
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09525
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00121
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85923
BRD-K10987837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22067
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.16836
Rosiglitazone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
BRD-K88000297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72039
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7213-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898131
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.546803
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02613
HMGN3	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59648
bezafibrate-6653	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K40935524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1513
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ID1_01_117	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60404
JUND_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919438
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546136
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
luteolin-5004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43651
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835916
BRD-A44438286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33327
Autosomal dominant nonsyndromic deafness 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
trans-Golgi network membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06313
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	128.278
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Psoriasis	DisGeNET Gene-Disease Associations	1.0	null
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prestwick-1100-4534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12311176-41408_2025_1333_MOESM2_ESM.xlsx-Table_S10-Table_S10_SOX11_SMARCA4-direct_target_genes_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07145
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12363_KD_SNRPE_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.58971
Spinal trigeminal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
SFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26052
furaltadone-4313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
levodopa-4394	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ramipril-6792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_289_KO_PHF8_SRP399627	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.58055
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153341_2_v_3_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05194
Perturb_12971_KD_GATA3_SRP372594	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.2819
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98897
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
lansoprazole-6009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00205
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42911
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9858_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.54593
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.77411
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.928283
Perturb_14881_KO_H15_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.37212
Labellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.111
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.89031
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97585
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06367
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052785
Perturb_474_KO_HDLBP_SRP261899	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.40226
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.84436
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27991961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07666
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15611
YH-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24229
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
early endosome membrane	GO Cellular Component Annotations 2023	1.0	null
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.26573
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18568
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00578
BRD-A45607610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3022
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-5417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67092184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26516
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963497
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35368
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTOV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82067
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72659
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.9641
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249971
BRD-K12336887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2592
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9701
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.526
ACN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6074
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852913
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33817
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85496
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04174
SUPB15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68609
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14624
BRD-K63107801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2036
altizide-6089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19333
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K42361742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57696
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4768
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873408
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30252
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56491
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26366
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
RUNX1	ChEA Transcription Factor Targets	1.0	null
Perturb_14675_KO_RpL13a_SRP090469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.4467
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955905
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063322
tetrahydroalstonine-5728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26387
BRD-K19269952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31922
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3-21867929-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35174
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3634
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.987762
Perturb_7745_KD_RRP6/DIS3_SRP062389	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.9076
Allpo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97438
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17996
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17883
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98818
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40734
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27375
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NB-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967545
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20053
Primary somatosensory area, upper limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20099
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75319
etamsylate-4399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993707
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CXCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52706
HCC1599	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60013
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08725
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TTF2	ChEA Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65994
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.991867
SUIT2	DepMap CRISPR Gene Dependency	1.0	2.27658
Kidney-b cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0315523
BRD-K82362034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28238
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20508
BRD-K30937829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38116
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.545772
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57002
hsa-miR-1254	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Synaptic vesicle, readily releasable pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.213
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-519b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC4609150-13073_2015_228_MOESM2_ESM.xlsx-TP53-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heinz body anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
Neurosecretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
outer SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04154
mephentermine-7384	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXP2_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3282
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6429
trichostatin A-6910	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73627
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dextromethorphan-5401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20883
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13464
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0104
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.828606
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17037
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060096
Guanfacine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.55
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041562
BRD-K59437706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24228
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82107155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20692
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941289
RAB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50808
NCI-H810	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841623
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal inhibitory postsynaptic currents	MGI Mouse Phenotype Associations 2023	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S13-Table_S13_MR_resluts_of_brain_pQTL_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K56942203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19237
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16681
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38294
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41289
RBMX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40668
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROX1_01_06	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58867
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954847
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33234
MYC	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.885199
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72059
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041085
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843063
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61614
amoxicillin-5385	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MMAC-SF	GDSC Cell Line Gene Expression Profiles	-1.0	-1.98102
brain	HPA Tissue Gene Expression Profiles	1.0	0.966991
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acitretin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.44
BRD-K01639528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46208
CDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32981
Perturb_8868_KD_PNN_SRP063860	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.15128
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.971874
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79388
Perturb_3063_KO_31O21Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93589
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824014
HSPBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23845
GSE176008_0_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH716	CCLE Cell Line Gene CNV Profiles	1.0	1.51817
trichostatin A-6891	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATP1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26839
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.92996
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968146
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.852532
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26743
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03487
Ro-3306	DeepCoverMOA Drug Mechanisms of Action	1.0	0.74
MCF7_Quisinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00562602
trichostatin A-5625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0504
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.6232
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96925976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23423
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42769174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23118
TMEM190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14908
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75776
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.71182
RAB23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33256
Perturb_9838_KD_GCN2_SRP248465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.14463
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53052
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02305
Perturb_11837_KO_Slc45a3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.5416
Perturb_16781_KD_Msi2_SRP061564	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.68844
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135514_8_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54088
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94744
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893097
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Small cell sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.883
pancuronium bromide-4393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.927961
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965665
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20864
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.920589
DU4475	DepMap CRISPR Gene Dependency	1.0	4.5551
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54104
AKT1_knockdown_141_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.74708
ampyrone-2249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
early endosome	GO Cellular Component Annotations 2025	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31878
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2511
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
POR_KO_GDS1678_762_mouse_Jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PPP1CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57001
endosome membrane	GO Cellular Component Annotations 2023	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01527
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.57813
NDUFAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51049
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.992717
BT483	CCLE Cell Line Gene Expression Profiles	1.0	1.42036
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76274
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38401
KDM4A	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57569
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965826
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	1.27138
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49483
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45938
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73200916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30507
GSE133683_3_v_5_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAOV4	DepMap CRISPR Gene Dependency	1.0	3.90025
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03433
acacetin-4324	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10998_KO_Lyplal1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.54244
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.65884
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_6871_KD_HHEX_SRP323378	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.63732
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.859252
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27066
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK1_knockdown_145_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.65109
xylometazoline-2107	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63883
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0488
MLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53728
Late endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Spadix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464124
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53508363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25147
Perturb_1048_KD_H19_SRP132802	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.6384
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1521
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
hsa-miR-4691-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
peripheral primitive neuroectodermal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.664372
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42259
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-324-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
trichostatin A-4153	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	1.0	0.881983
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79376287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20925
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
KM03430	DeepCoverMOA Drug Mechanisms of Action	1.0	0.43
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05798
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anxiety	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02266
ATP5MGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33349
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12188
famotidine-6665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Amyotrophic lateral sclerosis type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04689
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32831
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17167
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1379
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32696
CTBP2	ENCODE Transcription Factor Targets	1.0	null
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86295
Myosin X complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.837
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24712
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49341
CTNNB1-20615089-FETAL_BRAIN-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11812
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904809
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29235
H2722	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAKI2	CCLE Cell Line Gene CNV Profiles	1.0	1.57656
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89546
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63781
BRD-K94629607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01587
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94174
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_EZH2-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67782
ASPC1	CCLE Cell Line Gene Expression Profiles	1.0	2.07523
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LGALSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5341
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-R3-A69X-01A-22R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53720386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3044
positive regulation of neurotransmitter secretion	GO Biological Process Annotations 2023	1.0	null
BRD-K65259629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69715
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982752
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36983
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58781
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2025	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50206
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29996
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05502
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51803
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18173
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9533
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08445
Perturb_482_KD_IFI16_SRP298943	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.10988
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57425
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76915
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A702-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06511
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-7550	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08461
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
syntaxin binding	GO Molecular Function Annotations 2025	1.0	null
CS1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
papaverine-6245	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11953091-12035_2025_4695_MOESM1_ESM.xlsx-s5-Supplementary_Table_5_Results_of_the_2-sample_pQTL_MR_on_insomnia_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.99578
BRD-K81779733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10494
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31032
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Floral meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.617
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883731
dense core granule maturation	GO Biological Process Annotations 2023	1.0	null
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49506
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Quinidine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13015
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.936749
BRD-K17339982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59693
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41627
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834128
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K16715205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07822
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62367
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3348
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40566
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07548
Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36087
NCIH1944	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7087
substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.455601
H3K27me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.25798
amprolium-4825	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88689
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52576
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Macular degeneration_Fibroblast_GSE1719	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68716
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64994
Posterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
ATF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09477
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62511
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852172
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93849
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23556
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213797
SDHAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57387
cefalexin-5250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_14878_KO_H14_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.2709
BRD-K69585439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32069
Autosomal recessive nonsyndromic deafness 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
prenylamine-5070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68836091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06171
betahistine-2833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lorglumide-5254	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
iopanoic acid-2965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09522
BRD-K86964464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00353
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301354
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09939
COX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02847
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.72218
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00819
Perturb_14759_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.00858
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02181
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833833
t62-spleen_male_8w	MoTrPAC Rat Endurance Exercise Training	-1.0	-1.98528
GSE129772_2_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263327
BRD-K63180587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39357
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99878
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34217
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.0153
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415537
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61185334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17138
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FN-7833-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5338_KO_Haunt_SRP044012	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.60341
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.6497
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SM-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.943831
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ketanserin-6649	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.18245
GNG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.54183
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74974
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.895266
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50823
CASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17283
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21502
CAL62	CCLE Cell Line Gene Expression Profiles	-1.0	-2.4029
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44344
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB14	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57773
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54172
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K78625574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33723
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11671
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10952_KO_70L02Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.46029
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96779
Primary somatosensory area, barrel field, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30945
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11845
BRD-K12089436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05645
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37888
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877032
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9919
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7047
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73
trichostatin A-7499	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	141.894
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969117
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.47251
methotrexate-6654	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3289_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K43771394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39036
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.0744
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85063
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5893-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63829
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dense core granule	GO Cellular Component Annotations 2023	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.409578
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4949
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895735
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	0.971483
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03819
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6B-Table_S6B_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_Type_II_LGG_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39949
BRD-A12822115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23718
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52011
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMIM10L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54878
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98415
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC43A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9237
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97155
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16846
Perturb_6262_KD_NDP_SRP188348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.301
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25449
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64442
chr16_1333326_G_A_b38	GTEx eQTL 2025	1.0	1.85352
Primary somatosensory area, mouth, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03233
increased susceptibility to pharmacologically induced seizures	MGI Mouse Phenotype Associations 2023	1.0	null
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_18440_KD_CGAS_SRP303519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.30191
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39803
RH18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59626
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54527
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE113221,GSE113968_6_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Urinary system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
BT-483	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02345
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
C22orf23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73006
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05042
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Fetalliver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02763
probucol-5261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.90512
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51081
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59873
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
Isolated microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
RPL26L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20401
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63879
methoxamine-6627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6222
ABHD16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51823
UBTF	ENCODE Transcription Factor Targets	1.0	null
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95519
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08997
OCUM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06135
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04692
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328464
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.322414
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4095
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63242692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25791
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1817
TMEM139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0277
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.37003
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57921
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K58193973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54894
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.03695
Kidney benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27811
Blastoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fluvoxamine-4114	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
homatropine-5477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900063
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943635
oxybuprocaine-1976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK-GT-2	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
Perturb_8273_KD_RPS19_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.72249
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
3-nitropropionic acid-6372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE237040_2_v_3_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.20757
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DOC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20469
Substantia innominata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endosomal transport	GO Biological Process Annotations 2023	1.0	null
BRD-K15028327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21564
EC-GI-10	GDSC Cell Line Gene Expression Profiles	1.0	1.43282
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855445
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-2581-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43317
protein binding	GO Molecular Function Annotations 2015	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21108
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LY-294002-6186	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92635
Perturb_3452_KO_Plp1_SRP073495	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.00407
JUND_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00969
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36805
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52489
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26904
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13542
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10322
trichostatin A-2794	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40334
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K11518913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50148
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85079
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977185
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18235
cinoxacin-6257	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of PCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18568
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21883
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.6762
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26585
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39557
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gender	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.308
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56936
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851514
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851613
TXNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24028
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
iohexol-4643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal miniature inhibitory postsynaptic currents	MGI Mouse Phenotype Associations 2023	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MEIOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52313
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05821
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03546
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53245
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_3261_KD_TFAM_SRP089927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.46869
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.968176
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neurotransmitter secretion	GO Biological Process Annotations 2015	1.0	null
Visceral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.793
HDAC6_KO_GDS4375_532_mouse_Foxp3(+) Tregs	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01666
GSE183316,GSE183317_4_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081413
BRD-K68118416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52237
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81167
physostigmine-2768	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88853
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94414
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84492
Perturb_16944_OE_Snca_SRP280164	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
molt4	HPA Cell Line Gene Expression Profiles	-1.0	-0.935006
BRD-K55916310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14545
SOCS3_DELETION_GDS1254_80_mouse_ES (embryonic stems cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1559
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
Perturb_2133_KD_HAPSTR1_SRP377309	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.33219
Type 2 diabetes mellitus_Muscle tissue_GSE12643	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.7558
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.904917
BRD-K97359891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83684
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
delsoline-7212	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.09295
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0197
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-520c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38982
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.78419
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.382245
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937296
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BV-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.737299
MM1S	DepMap CRISPR Gene Dependency	1.0	6.59649
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.6241
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.850809
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24529
BRD-K23535862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01837
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36225
BRD-K84158675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78243
BRD-K93927229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32062
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.61407
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01237
Perturb_15021_KD_RelA_SRP078053	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.4868
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89275
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13028
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Perturb_14662_KO_Ogt_SRP198294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
dexibuprofen-6471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831295
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19575
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
alpha-estradiol-5207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K37203382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0353
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RT-112	GDSC Cell Line Gene Expression Profiles	1.0	1.4705
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.84694
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15559
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	0.847926
fasudil-436	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880737
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54147
SW626	DepMap CRISPR Gene Dependency	1.0	2.00472
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73355908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0413
molsidomine-5426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
neurotransmitter transport	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EHEB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18191
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.23197
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220287_2_v_1_mef2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61431055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06375
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255984
Perturb_3277_KD_RORA_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_4_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
0317956-0000-4334	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53087
positive regulation of secretion by cell	GO Biological Process Annotations 2023	1.0	null
BRD-K95712112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30103
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09761
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912189
Perturb_3095_KO_Klf14_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.39218
PMC10681890-41375_2023_2059_MOESM8_ESM.xlsx-Sheet1-Supplementary_Table_S8_Upregulated_or_downregulated_genes_in_ATL_cells_stratified_according_to_TP73_SVs_TP73	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
TEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11636
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17217
Epithelial lining fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.68782
Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22485649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06128
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TC32	DepMap CRISPR Gene Dependency	1.0	2.46615
POLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8369
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19462
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86439
BRD-K37304120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2302
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04658
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.26311
Perturb_8737_KD_DDX3X_SRP198641	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.5234
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94411
Tandutinib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66503
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36089
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81403
BRD-K52170475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67438
Perturb_3875_KD_PLK4_SRP333146	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.262
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06325
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56885
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01861
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.41407
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TMEM205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24151
trichostatin A-5231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.480836
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19333
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.0563
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3282
midecamycin-5345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFAND2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88926
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.5458
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48689
chr16_1330651_C_A_b38	GTEx eQTL 2025	1.0	1.6448
Perturb_2307_KD_DDX3X_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.16118
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.890709
regulation of neurotransmitter secretion	GO Biological Process Annotations 2023	1.0	null
t62-spleen_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.41934
Perturb_17738_KO_Phf8_SRP093797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.81114
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25452
ZNF263_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10269761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48385
Inflorescence meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.548
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.279335
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65274
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26325
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19392
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6668
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95729
NB10	DepMap CRISPR Gene Dependency	1.0	2.12539
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.944956
Perturb_5600_KD_ESCCAL1_SRP259187	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.63636
trichostatin A-1471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nephroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.468063
DU145	BioGPS Cell Line Gene Expression Profiles	1.0	0.828879
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.051
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65725
BRD-K99455613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20111
L33	DepMap CRISPR Gene Dependency	1.0	3.66706
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7764_KD_RRP40_SRP062389	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.83371
trichostatin A-7503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881093
Perturb_14745_OE_MEOX2_SRP330486	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.6726
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24082
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.56253
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5327
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33956
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10927
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
BRD-K88997070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06376
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.870282
early endosome	GO Cellular Component Annotations 2023	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03246
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.70822
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
homosalate-4533	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11618
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.68328
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.06502
BRD-K14364923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31474
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21386
BRD-K83892314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80373
Perturb_9544_KO_Ucp1_SRP187003	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.93089
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06479
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75306
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10387_OE_DRP1_SRP333953	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MCF7_Pracinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00504372
Perturb_4305_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.0373
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.29969
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3029394-pone.0016617.s001.xls-Down-regulated-Table_S1_Genes_down-regulated_by_SOX2_over-expression_0_5-fold_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
NFATC1_02_22	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59567
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31696
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
Measles Chicago-1_24Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.5537
GSE151160_0_v_1_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.832638
CCNT2	ENCODE Transcription Factor Targets	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
LRRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89738
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05837
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77894
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835209
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25079
TT2609C02	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46129
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nomegestrol-5461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
protein c-terminus binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67909
SMC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88292
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843716
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893234
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63879
Perturb_11792_KO_Ctdspl_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.64544
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11004_KO_Nhlh2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.47499
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.561221
BRD-K66807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27361
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.987762
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17075
ZNF263	ENCODE Transcription Factor Targets	1.0	null
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13206
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.46616
Perturb_3193_KO_DLAT_SRP266195	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.93069
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.281
TUBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62598
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K89260735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27637
TAF7	ENCODE Transcription Factor Targets	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.2575
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.932264
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33856
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51791
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8626-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851709
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15982
JHH1	CCLE Cell Line Gene Expression Profiles	1.0	1.42568
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826539
Anxiety	DisGeNET Gene-Disease Associations	1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48185
BRD-A66164310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67538
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974264
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31912
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865084
hsa-miR-642b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_7751_KD_RPP20_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.40638
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12731
Perturb_7980_KD_Kmt2d_SRP253323	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.2639
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK2_knockdown_146_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.28504
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34794
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2827_OE_ERK1_SRP064353	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.08368
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6471
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
not applicable_Hypothermia_GSE54229_131_mouse_Embryonic fibroblas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_9863_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.51774
Perturb_15966_KO_Tbet_SRP063567	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.8697
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27717
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.0935
positive regulation of synaptic transmission	GO Biological Process Annotations 2023	1.0	null
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mouse - Motor Cortex - Cluster - Sst+ Penk+ GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
Perturb_15527_OE_CPT1A_SRP292168	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.70832
Autosomal recessive nonsyndromic deafness 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
H3K27me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33315
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925601
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911909
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43436
BRD-K17175263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31364
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48031
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JI-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10484
PMC8299217-mmc3.xlsx-Early_Resp_FOXJ1_high_Ciliated-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05238
GSE210885_2_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00637
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90048
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38804
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21642
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
CCDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8559
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.89723
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Supplemental_Table_8_NEUROG3_bound_genes_and_expression_in_islet_lineage_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0833
MXI1	ENCODE Transcription Factor Targets	1.0	null
MED28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66742
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.29969
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-A549_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_A549_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67120755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6831
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40281
Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6216_KO_Mef2c_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.185
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
INS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
mafenide-5079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864331
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135350_2_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36547
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92856
BRD-K87554792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00441
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS944T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51085
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1726
COLO824	DepMap CRISPR Gene Dependency	1.0	3.92742
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26753
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60342
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16189
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
methylphenidate_mus musculus_gpl11180_gse33619	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34673
Perturb_12546_KO_Shank2_SRP309197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.31336
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39583
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus solitarius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SCABER	DepMap CRISPR Gene Dependency	1.0	2.03482
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23443
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82317
Seizures	HuGE Navigator Gene-Phenotype Associations	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72351789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00183
RI1	CCLE Cell Line Gene Expression Profiles	1.0	1.75086
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31095
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936531
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24784
Perturb_2557_KD_NXF1_SRP226431	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.31897
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927311
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	130.593
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00015
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K07756997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67213
AM-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42742
HS821T	CCLE Cell Line Gene CNV Profiles	1.0	1.47932
pivmecillinam-7312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33635
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03443
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31839
galantamine-2787	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8316
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1757
BRD-K43624274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25019
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INTS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06176
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.848
Perturb_3287_KD_RORA_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MCF7_Panobinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00702242
dihydroergotamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4034
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53762
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14756138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22963
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29023
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.614883
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1581	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suxibuzone-6065	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K84115096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3621
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.91
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12522
estradiol_homo sapiens_gpl14550_gse35034	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.50767
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	1.0	1.43146
LN443	CCLE Cell Line Gene CNV Profiles	1.0	1.37178
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
regulation of insulin secretion involved in cellular response to glucose stimulus	GO Biological Process Annotations 2025	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50119
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20875
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0535
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910469
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59862
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
BRD-K71625503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00929
GSE155567_2_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4487	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12026
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36984
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32819
smooth muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.889621
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26091
HC-01-FD24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254856
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2347	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49977
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846791
HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34454
GSE200839,GSE233826_2_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7099
pepstatin-3264	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.887376
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96707
SYT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30571
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1959
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24792
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.28352
PMC10315050-12920_2023_1588_MOESM2_ESM.pdf-12-SKOR1_SKOR1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_3291_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
Midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.208
Decidua basalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
PSMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61534
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993018
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OTUD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96463
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55923
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K42435237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51585
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1713
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.913537
Recycling endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73979
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12486367-Supplementary_Data2.pdf-205-LIN54_LIN54	Rummagene Transcription Factor Associations 2026	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05042
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
Supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968206
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36841
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prilocaine-3624	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7899452-media-5.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03591
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.594
Natural killer cell_Spleen_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X1-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_860_KO_Tsga8_SRP254760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19898
GSE202434,GSE202438_6_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_WHSC2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_2289_OE_NRP1_SRP124497	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.1535
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11548
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77867
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36805
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07881
Perturb_8881_KD_CSL_SRP142324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.20629
trichostatin A-5945	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.4427
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04776
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82989
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE76425_1_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
hesperidin-6714	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rolitetracycline-5331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100650_TCx_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.69967
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15245
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05319
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
thalidomide-266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06842972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26217
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36847
CHLA266	DepMap CRISPR Gene Dependency	1.0	2.4345
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16484
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H2AC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4258
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3342
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980427
NCIH460	DepMap CRISPR Gene Dependency	1.0	3.00075
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06282
BRD-K73088636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68777
BRD-K12441550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21173
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10801
mesoridazine-7017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00178
theobromine-4958	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55105453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89047
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91057
FGFR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63471
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	3.21352
Perturb_8867_KD_PNN_SRP063860	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.40164
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.70352
MITF	ChEA Transcription Factor Targets	1.0	null
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7698
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30726
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.7159
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R0-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02292
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37401
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.67416
Perturb_13113_KO|KD_Mbnl1/Mbnl2|Mbnl3_SRP045573	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.96989
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19684
BRD-K66288362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55462
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
modulation of chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990944
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
Primary somatosensory area, mouth, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07273
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2078_OE_PUM2_SRP072710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.42015
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14225
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
secretory vesicle	GO Cellular Component Annotations 2023	1.0	null
Perturb_5706_KO_Abcc8_ERP119268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37116
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34977825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22292
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51363
CCDC90B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63023
ADGRG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7645
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01813
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00846
BI 2536	DeepCoverMOA Drug Mechanisms of Action	1.0	1.86
increased thigmotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAGE_knockout_269_GSE22873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.67385
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
Spinothalamic tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.13144
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0258
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16768
metal ion binding	GO Molecular Function Annotations 2023	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20588
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469543
clomifene-6648	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IGF1_OE_GDS3484_540_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68062
trichostatin A-331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0426-SM-4BRUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09125
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28882
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44449
HuCCT1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66833
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42539
Perturb_11775_KO_83F24Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.72336
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17716
ATPAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18833
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24756
Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB	DepMap CRISPR Gene Dependency	1.0	3.71707
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.76433
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29862
trichostatin A-4954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10475
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6489
hsa-miR-1304	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K47511177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33285
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8574
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53983
Perturb_4306_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.31481
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20963
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0433
BRD-K59149254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2096
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95044
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21501
calcium ion binding	GO Molecular Function Annotations 2023	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70907
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0365
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18085
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19931
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65961
BRD-K17753780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11557
Perturb_15070_KD_Twist1_SRP150075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824572
Perturb_3594_KO_DELE1_SRP218218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.61552
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36845
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936531
Perturb_1440_KD_lncRNA12928_SRP174348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.59903
Perturb_8678_KD_AKAP8_SRP226172	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.31921
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47504
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967115
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19086
FOXO3	ChEA Transcription Factor Targets	1.0	null
C-75-6399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_9833_KD_TBX3_SRP122892	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.99843
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16061
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	141.269
Perturb_6213_KO_Dyrk1_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.37742
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87484
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75718
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02367
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43178
succinylsulfathiazole-2821	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15072
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22369
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69777784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.258
Perturb_9699_KO_RNASEH2B_SRP355094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.961329
Lung squamous cell carcinoma_LUSC_TCGA-70-6722-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2122
Perturb_3398_KO_Tcf7_SRP077563	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.18201
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gynophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42851
Perturb_12416_KO_STAMBP/USP8_SRP344246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.41639
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.61085
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37505
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988722
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55625
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52189
FOXO1-25302145-T-LYMPHOCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K57027644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49147
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29926
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.23736
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19834
GSE203158_1_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78605
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42781
NAMALWA	CCLE Cell Line Gene Expression Profiles	1.0	1.35427
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48185
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300095
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07293
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S14-Table_S14_MR_resluts_of_brain_pQTL_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal action potential	MGI Mouse Phenotype Associations 2023	1.0	null
GSE125155_3_v_1_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235066_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.971483
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85877
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.928953
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29215
BRD-K93567937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13619
YRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34611
signal transduction	GO Biological Process Annotations 2015	1.0	null
GSE130956_0_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H378	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00369
BRD-K75036062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18661
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63001
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05624
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43312
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13265
SH3GL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0975
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.487331
Golgi transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.369
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961709
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32496
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.06502
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48909
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gynostemium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.628
BRD-K36460068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.726
trichostatin A-6493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44778
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO320	DepMap CRISPR Gene Dependency	1.0	2.91177
GSE130956_2_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21195
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U4-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04343
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QI-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11158
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81774
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65603
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WR-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242167_1_v_2_cd40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGFP966	DeepCoverMOA Drug Mechanisms of Action	1.0	1.0
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52402
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01847
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7385
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.444765
hsa-miR-3116	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
JHUEM1	DepMap CRISPR Gene Dependency	1.0	3.77685
3-hydroxy-DL-kynurenine-2654	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trichostatin A-6951	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
regulation of neurotransmitter levels	GO Biological Process Annotations 2015	1.0	null
trichostatin A-3643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04481
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6611
GSE139966_5_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
raubasine-5459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17972
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0814
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921463
BRD-K77814566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07641
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5456
hsa-miR-519c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE183316,GSE183317_3_v_5_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4868_KO_NEUROG3_ERP110708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.65609
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17987
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97686
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21186
Rheaume et al.Nat Commun.25_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01461
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959049
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.82377
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SUCS-1126-SM-4DM61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908207
GSE152379_0_v_4_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Extravillous trophoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4514
netilmicin-6005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846488
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16935435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54878
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04556
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47072
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
secretory vesicle	GO Cellular Component Annotations 2025	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39513
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879343
U-2-OS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06159
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_7306_KD_IER3_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.70709
mecamylamine-7023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57296
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17075
NFYB_01_238	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.0079
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33912
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74739
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928426
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42388
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61973443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22205
GSE223908,GSE223909_1_v_6_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19863
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
SLVL	DepMap CRISPR Gene Dependency	1.0	3.26986
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0006
CTNNB1-20615089-FETAL-BRAIN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32769
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OCUM1	CCLE Cell Line Gene Expression Profiles	1.0	1.80953
chlorhexidine-1525	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_15017_KI_Stat6_SRP374172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.3156
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18229
clomifene-4994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_13067_KO_Ube3d_SRP373803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.21553
trans-Golgi network	GO Cellular Component Annotations 2023	1.0	null
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hereditary mixed polyposis syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.450683
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.9336
trichostatin A-2247	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879808
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.944214
Golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Stinger	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29756
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08679
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14413
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	2.18987
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31981
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07321
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04558
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.07139
PEA1	DepMap CRISPR Gene Dependency	1.0	3.41527
Perturb_3280_KD_RORC_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12212
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3271
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CD-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_4_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.845905
BEN	CCLE Cell Line Gene Expression Profiles	1.0	2.8257
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050512
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96848
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.06502
hsa-miR-329	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81113
Diabetic cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21986
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79039
Perturb_10927_KO_Mettl3_SRP363782	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.01284
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nordihydroguaiaretic acid-6983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.971483
Perturb_705_KD_SETDB1_SRP116954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.446
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52153
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966402
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0905
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
regulation of dense core granule exocytosis	GO Biological Process Annotations 2025	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3558
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81455
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31584969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48759
KDM5A	ENCODE Transcription Factor Targets	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834256
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29272
Perturb_3399_KO_Tcf7_SRP077563	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.9586
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ILRUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15494
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03506
BRD-K15923694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13453
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1442_KO_Stag2_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.48819
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.487027
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28286
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950271
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.4314
ZNF184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25781
Perturb_12542_KO_ADAR_SRP194087	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.3214
FANCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59459
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.927276
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5293_KO_Dgcr8_SRP137730	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.57204
guanfacine-5256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hydrocotarnine-2765	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047289
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953007
PMC12933612-mmc2.xlsx-eTable_14_Gene_sets-MULLIGHAN_MLL_SIGNATURE_2_DN_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52252
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HKA1	DepMap CRISPR Gene Dependency	1.0	3.7068
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	6.78021
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2255
BRD-K38244121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57034
GSE242199_6_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DUSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8572
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25854
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10671
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449821
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20519
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069963
Motor trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947866
ZBTB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15133
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
BRD-A96007399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73591
GSE135350_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4701-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-608	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846081
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936531
SIMA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.55516
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.919909
Perturb_11014_KO_Popdc3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.27864
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81565
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.384
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69888
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987136
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.708834
PMC4063835-epi-9-760-s02.xls-MI_vs_NU-SYMBOL_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2950-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW156	DepMap CRISPR Gene Dependency	1.0	2.97915
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936531
Perturb_7424_KD_CPSF2_SRP045481	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.3775
Perturb_3632_KO_HDAC8_SRP355605	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.95338
Perturb_7596_KO_PRPF39_SRP389969	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.21933
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
HTRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24164
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5463
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09374
BRD-K78262424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.282
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15402
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31512
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72265
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01533
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
TCCPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.50725
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04379
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K48050202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60291
Perturb_14874_KO_H12_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.93102
MCC26	DepMap CRISPR Gene Dependency	1.0	2.97948
GSE222829,GSE223009_0_v_1_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884114
BRD-K96438475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04956
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11447
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0614
Desmoplastic small round cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.946
SW954	DepMap CRISPR Gene Dependency	1.0	2.85399
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21102
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.886844
liothyronine-4947	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
(-)-MK-801-6458	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
Leaf primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
GSE193624_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06697
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02938
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.90686
Autosomal recessive nonsyndromic deafness 61	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
chloramphenicol-5466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4981
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35703
bambuterol-5885	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NALM16	DepMap CRISPR Gene Dependency	1.0	6.05616
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31321
BRD-K47658117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38511
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66171
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU668	CCLE Cell Line Gene Expression Profiles	1.0	2.20031
Perturb_7383_KO_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.44876
BRD-A98099470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51497
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19257
Pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82217056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06674
BRD-K42465630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18048
etanidazole-6072	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20064
BRD-K08247496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63386
syntaxin binding	GO Molecular Function Annotations 2023	1.0	null
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060498
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41993678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26367
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74845
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27251
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9087_KD_SSRP1_SRP106869	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.02805
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prestwick-682-2819	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99789
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06307
Perturb_8833_KO_RING1A_SRP345831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_14879_KO_H14_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.21393
Rovs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38834
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35737
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.55128
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25959
Thymus-memory b cell	Tabula Sapiens Gene-Cell Associations	1.0	3.6119
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
nabumetone-5428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
Perikaryon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.566
Perturb_9332_KO_CDKN2A_SRP158424	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.54287
Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.707356
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_16514_KD_Pou2f3_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.4828
Perturb_9887_KD_BUD13_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33513
Cco	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.598
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
canrenoic acid-6783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_7381_KO|KD_SMG7_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41327
Pepstatin A	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.66
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abamectin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07595
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8809
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11616
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09528
BRD-K00359952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0789
BRD-K48276655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00582
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
signal release	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8299217-mmc3.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.63735
Primary somatosensory area, barrel field, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06948
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27572
Perturb_8883_KD_CSL_SRP142324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.31231
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13142_KO_Ngly1_SRP166093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.3654
COLO783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73561
Perturb_2076_OE_PUM1_SRP072710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.23363
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CCNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9405
BRD-K31363949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3763
BRD-K45028867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41907
Perturb_8368_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.28068
BRD-K64111129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20283
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61737
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stroke	GAD Gene-Disease Associations	1.0	null
ATP5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03247
COLO205	DepMap CRISPR Gene Dependency	1.0	2.47004
GSE202587_1_v_2_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
BRD-K90934902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50053
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S4-Supplemental_Table_S4_Genes_commonly_upregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
nitrofural-3320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BL1797 (BCL11A)	NURSA Protein Complexes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07516
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6209
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26787
KE37	DepMap CRISPR Gene Dependency	1.0	5.49004
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	2.00152
BRD-K86077185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19477
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61243
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31162
Perturb_5553_OE_BAHD1_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.59657
18172295-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.91275
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26746
BRD-K90749965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34849
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.072937
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841708
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_13_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27373
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
P4HB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12555
A101D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF665	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58943
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51323894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63002
Spinocerebellar ataxia type 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01886
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847331
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7648
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-A_ATF4-def_vs_HCT116_ctrl-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53666
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22892
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39968
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.09038
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.914993
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.081
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00262
MRTFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94999
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22286
valinomycin-5957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31368
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
BRD-K13049124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23999
BRD-K62170825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9101
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22281
Prestwick-664-4737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.13771
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06275
ESR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63089
BRD-K30382953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07935
NCIH1395	CCLE Cell Line Gene Expression Profiles	1.0	1.52946
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65196043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02584
SCLY	ChEA Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03284
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73744
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00319
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2595
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of dense core granule exocytosis	GO Biological Process Annotations 2023	1.0	null
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35379
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
chlorphenamine-2055	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
nalbuphine-2225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MOSPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32749
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981958
Perturb_11380_KD_GATA2_SRP178865	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.99765
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06105
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847406
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87802
BRD-A25883214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30177
Medial mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19609
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07307
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77125
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8555
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0615
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K42486632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42192
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10858
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A37645929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72036
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937221
BRD-K76900919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56568
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22789
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_14763_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.98433
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38286
sulmazole-4009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nordihydroguaiaretic acid-6942	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chloroquine-2869	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
High light scatter reticulocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
Perturb_7489_KD_SIN3A_SRP173465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.31885
2,6-dimethylpiperidine-3806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1052
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16079077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03004
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989922
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.315919
Perturb_10099_KD_HNRNPU_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.73848
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949153
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43293
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60847
Small_Intestine-b cell	Tabula Sapiens Gene-Cell Associations	1.0	1.23938
BRD-K65933652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26215
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVCAR-5	GDSC Cell Line Gene Expression Profiles	1.0	2.18917
Pancreas-pancreatic beta cell	Tabula Sapiens Gene-Cell Associations	1.0	0.786445
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.335
Perturb_4720_KD_Tp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K73462370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1102
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gata3_22922362_treg_cd4poscd25posyfppos_lof_mouse_gpl8321_gse39864	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.19268
BRD-K14599588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09135
PMC4580636-pone.0138782.s005.xls-Sheet1-Table_S3_List_of_Genes_with_RUNX1_binding_sites_in_each_Cytogenetic_Group_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10395
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29812
BRD-K26826253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74435
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63098
Perturb_8334_KD_HCF1_SRP178073	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.93597
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58038
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00296
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
capan2	HPA Cell Line Gene Expression Profiles	1.0	1.70012
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K98941192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58212
GSE109111_2_v_0_stim1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Medial vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1092	GDSC Cell Line Gene Expression Profiles	1.0	1.44285
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38437
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0872
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	2.44509
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZW10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23988
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.372958
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227588
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24068
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71262871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04369
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73577714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3525
INS-1 823/13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
trichostatin A-873	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
protoveratrine A-2800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51946
Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45609222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90536
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998338
hexetidine-5420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_15034_KD_WDR5_SRP024294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.94322
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00496
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
Cell envelope Sec protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55G-0426-SM-48FDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903954
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14201_KD_HNF4A/GATA6_ERP108557	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.3279
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24398
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86879
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835041
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852172
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911909
BRD-K47326075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19191
Perturb_240_KD_CYFIP1_SRP061192	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.96651
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.3391
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29266
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69814
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852172
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perianth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.853
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22835
praziquantel-7228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9966_KD_SF3A3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.8599
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4629
BRD-K23860926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12382
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19992
BAI1	Pathway Commons Protein-Protein Interactions	1.0	null
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894519
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39548
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02237
Perturb_313_KO_CARM1_SRP279319	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918203
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.913263
Substance-Related Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
Juvenile polyposis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05022
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73648
BRD-K81949875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53793
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.73036
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55405
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.29969
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38356
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05098
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052159
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-127-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54871
FOXA1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75649
hsa-miR-4652-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38898
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35208671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00887
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16825
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.562433
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074186
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08041
LN464	CCLE Cell Line Gene Expression Profiles	1.0	1.3855
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17802
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75904236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29768
PMC10534007-Table_2.xlsx-S3_unique_up_MSC_V-817_elements_included_exclusively_in_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
homochlorcyclizine-5998	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_13206_OE_Klf3_SRP281992	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.18647
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43956
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48184
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.23768
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LY-294002-5965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	177.151
BRD-K05957858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03974
ATP5PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33101
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86966
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06858
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05528
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6639_KD_ZBP1_SRP298473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.7115
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96814
trichostatin A-7236	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ESRRG_ESRRG	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF528	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60452
BRD-A28932952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44843
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203158_12_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
Periventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K22668106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0114
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.950266
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64393896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31492
Polycystic kidney disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06579
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.017
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826358
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55717
timolol-6483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FASTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18905
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	1.97101
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.061
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2261
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.89495
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K80198069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17217
Perturb_13716_KO_BAP1_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.7412
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.142
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22157
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137914_0_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
benzonatate-6334	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852924
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PNU-0230031-3732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935204
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849419
Corolla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.868
SNU1041	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58722
BRD-K35132745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15081
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE144481,GSE144483_0_v_3_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cefaclor-2483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLR25	CCLE Cell Line Gene CNV Profiles	1.0	2.09853
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.13115
trichostatin A-6551	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NCIH226	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61641
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05788
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parietal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18568
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.415
PMC8586238-41467_2021_26788_MOESM6_ESM.xlsx-S2A_CDE_genes-S2A_CDE_-_genes_of_the_two_CCD_genes_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00459
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20053
BRD-A28153253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01709
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33752
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25018
velnacrine-4997	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.06502
Perturb_4719_KO_Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17017
BRD-K96254487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15365
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27354
PMC11801220-NIHMS2038999-supplement-15.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061681
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78087
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.57248
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.61192
BRD-K06729289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30307
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26247
hsa-miR-4707-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_13279_KO_Ythdf1_SRP254797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.04282
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78445
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxymetazoline-2278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651