association	dataset	threshold value	standardized value
BRD-K69492024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24828
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5876
GNAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20104
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.083485
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19M-06A-61R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9612
Root quiescent center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
LRATD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74053
cell part	GO Cellular Component Annotations 2015	1.0	null
MB21D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65918
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
18537972-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Persistent hyperplastic primary vitreous	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
cataract	GeneRIF Biological Term Annotations	1.0	null
Congenital stationary night blindness 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80321
Cytochrome b6f complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.323
BRD-K45112293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05694
YTHDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50393
filament	GeneRIF Biological Term Annotations	1.0	null
TCF7	ChEA Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1863
plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.16799
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42798
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836825
RHBDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5291
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13241
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16868
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24383
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0461
MT-ND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71983
METTL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41421
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K27610371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08544
Diabetic cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
KARPAS422	DepMap CRISPR Gene Dependency	1.0	4.08275
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844372
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.42
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.314
cytochrome b6f complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.927483
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.20736
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12346
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6205
acute lymphatic leukemia	GWASdb SNP-Phenotype Associations	1.0	0.476654
Perturb_5549_KO_Wdr72_SRP353473	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58669
HT	CCLE Cell Line Gene Expression Profiles	1.0	2.39078
TCEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50101
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01494
Lung adenocarcinoma_LUAD_TCGA-55-8208-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04834
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21803
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62117
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71659
MATN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07547
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75664
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.533
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836825
DOV13	DepMap CRISPR Gene Dependency	1.0	3.18512
GSE155031_6_v_4_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.393549
lens	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.477636
CLPP_KO_GDS4791_537_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12634441-41375_2025_2771_MOESM8_ESM.xlsx-ATACseq-Table_S3_Bulk_ATAC-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2831
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
RND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3411
SNRPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68044
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1857
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.13702
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.3
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62268
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fibrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09915
BRD-K78866450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51151
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2734
FOSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34025
cataract	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65494
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62768
disease	GWASdb SNP-Disease Associations	1.0	0.047757
MMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96343
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.043523
ns0/1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.723
epidermolysis bullosa	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.255594
Carboxysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.702
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32264
BRD-K45612428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15652
BRD-K71592817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19049
Cryptosporidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.275
Chloroplast outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51212
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2657-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54321
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50458
GSE134191_6_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30711
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7055
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38997
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-8_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5427
Perturb_16944_OE_Snca_SRP280164	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06663
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DMS114	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63379
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.047785
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95183
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GPSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47739
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950418
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63115
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.46791
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
Plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.61
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863551
sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32999
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.907
NALM16	DepMap CRISPR Gene Dependency	1.0	2.07386
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.46358
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17787
first	GeneRIF Biological Term Annotations	1.0	null
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15932
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28634
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.14805
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82827604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01374
BRD-K71563254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36195
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dlx4_00000000_mcfdash7_gof_human_gpl201_gse21657	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.40612
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15697
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.450957
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97296
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306805
BRD-K32019201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27524
hypertension	GWASdb SNP-Disease Associations	1.0	0.531357
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7963
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74497
BRD-K35441510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09675
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1004
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.35179
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0695
APOE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82522
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00889
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
BRD-K01045229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20298
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Xanthomatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
SLC44A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27022
BRD-K85567359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23691
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00234
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.891863
KLK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85229
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92357
Dilated cardiomyopathy 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
NCI H226	BioGPS Cell Line Gene Expression Profiles	1.0	0.87213
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.865
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.859025
isotretinoin_homo sapiens_gpl8300_gds3215	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_1736_OE_NHD13_SRP068420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.0118
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26461
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.6277
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K97276563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09154
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26846
BRD-K24133768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36321
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
NCIH2196	CCLE Cell Line Gene CNV Profiles	1.0	1.5133
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3761
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88874
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982151
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.03468
MAN2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49433
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38646
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35103
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0185
CJM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77805
BRD-K06020071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34312
GPR120_KO_GDS4830_413_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GMNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60919
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90861
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QQ-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.844
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3047
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93459
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65389
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
BRD-K75584297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19651
BRD-K66577743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1228
BRD-K23064726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04244
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15695
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84875
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALKBH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77403
stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.05835
BRD-K84988480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0254
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
Axenfeld-Rieger syndrome type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.756
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051732
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20522
NFIC	ENCODE Transcription Factor Targets	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12763
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Signal recognition particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06801
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8065
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1711_KO_Chd4_SRP193857	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.68638
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
c83	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226155
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
Hyperplasia	CTD Gene-Disease Associations	1.0	1.14336
BRD-K64451677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14794
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4016
LIFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15994
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76573
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836113
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78285
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
cataracts	MPO Gene-Phenotype Associations	1.0	null
Sclerocornea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
EP300	ENCODE Transcription Factor Targets	1.0	null
MKNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
YIPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82207
locked-in syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
AKNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14372
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930292
binding	GO Molecular Function Annotations 2015	1.0	null
Leucoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
NAT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04823
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27442
Perturb_1269_KD_Sirpa_SRP392190	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cerebrotendinous xanthomatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
Plastid outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58052
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0341
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10247
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5672
epidermolysis bullosa simplex	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.572662
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11243
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
T47D	GDSC Cell Line Gene Expression Profiles	1.0	1.64182
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00377
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00565
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6862
SNUC5	DepMap CRISPR Gene Dependency	1.0	2.16767
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9526
BRD-K17372597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02482
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59561
filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.07172
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
BRD-K93819193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04128
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.239916
Eye disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1656
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31049
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7337
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11524
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36693
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78027
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.06011
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lower epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01381
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24747
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836825
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.264
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
COLO-741	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59533
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.47
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CAPN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5531
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
Norrie disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
varicose veins	GAD Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6211
HCT-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
DNAJC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12683
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30559
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.478
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
COPII vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00078
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74739
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53616
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49446
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Chloroplast ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
intermediate filament cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
19074828-TableS4	GeneSigDB Published Gene Signatures	1.0	null
Chlorosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.972
T47D	CCLE Cell Line Gene Expression Profiles	1.0	1.43515
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0104
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cataract	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Cataract 44	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
Congenital Cataract	DisGeNET Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Saos-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.8171
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875441
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21419
dominant	GeneRIF Biological Term Annotations	1.0	null
BRD-K23404017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40776
F-actin capping protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.104
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.935996
hsa-miR-3202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23597
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4284
mepacrine-3179	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plastid part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.18851
TCF4	ChEA Transcription Factor Targets	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46059
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.845039
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147662_3_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lens disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71997
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Large_Intestine-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	0.956585
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.633
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.16491
Chloroplast vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.56
Ghost	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
BFSP1	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.111257
lens nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.54971
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63618
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4497
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75913
Elaioplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.41445
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	2.18682
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941717
PR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
ABHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39326
SW1783	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07258
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69671285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22871
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24834
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
NEIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06388
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08281
KNSTRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87021
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48561
Hypanthium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74504
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98542
Hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63276
LB831-BLC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vesiculobullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.245396
BRD-K43414987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40634
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	2.31716
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95935
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06846
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74144
KP-4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.75278
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66169
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23624
BRD-K13275816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15888
BRD-K02093145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31041
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11914_KO_Id2/Id3_SRP041997	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.56147
GMPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01986
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35103
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90446
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-2.37945
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60169
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02154
microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.664769
g8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76214
BRD-K78015078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07775
BRD-K52881132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04736
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08997
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24967
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833011
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A-VN-1203-2004(H5N1)_Day1-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.5942
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48031
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.334
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0705
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052578
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.982
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19977
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.925
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.633
lens cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.408
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23288
Daudi	GDSC Cell Line Gene Expression Profiles	1.0	3.00795
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863551
BRD-K17133642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24982
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K31215362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02323
Chlorenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17345
Root pericycle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89263
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.137468
BRD-K73206088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71934
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23544
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.35079
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.467
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20412
BRD-K57059449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43506
PUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40058
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71344
BRD-K84235037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07944
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.320826
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91861
RANBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57626
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.2288
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83721
BRD-K78847404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06353
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73913
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28643
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94367
naloxone-5606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SH3D21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98034
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20049
Ascidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14261
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75217
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4829
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	0.938315
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42859
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33167
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03587
Cataract 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02709
lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.97082
lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.24803
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0057
SCRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
ERICH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13721
HUH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Congenital Lamellar Cataract	DisGeNET Gene-Disease Associations	1.0	null
BRD-K65598536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22014
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1385
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A8YO-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14309706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96109
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.936387
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19662
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69719
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.539
VTI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94082
ARH-77	GDSC Cell Line Gene Expression Profiles	1.0	1.89278
GSE154464_0_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10599
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24014
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71516
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07078
Replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.553
cataract	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03445
Cataract 12 multiple	ClinVar Gene-Phenotype Associations 2025	1.0	null
BRD-K62102480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41603
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30782
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80056
Plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.573
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.039622
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.86166
Varicose Veins	dbGAP Gene-Trait Associations	1.0	0.214089
denatonium benzoate-5480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ACSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02435
CLPP_KO_GSE40207_378_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
GATA1	ChEA Transcription Factor Targets	1.0	null
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45908502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17911
OCUBM	DepMap CRISPR Gene Dependency	1.0	3.34399
MAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70969
DDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66356
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15185
GSE164306_5_v_0_tsc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.967307
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38212
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.18334
FOXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40446
structural constituent of cytoskeleton	GO Molecular Function Annotations 2015	1.0	null
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0017
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
BRD-K75192396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01594
BRD-K03361106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0926
progressive	GeneRIF Biological Term Annotations	1.0	null
FBXO46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40767
CTTNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
NABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05339
BRD-K68364310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68653
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79345
PDPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70734
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52091
abnormal eye physiology	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15269
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.5
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19C-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.085974
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1451
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00154
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1536
Subiculum, dorsal part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.095
RXRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57637
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61354976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33284
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48641
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.934142
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.49851
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
SUDHL5	CCLE Cell Line Gene Expression Profiles	1.0	1.50866
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.81579
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.791
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26561
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09911
FADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80302
c-MYC_KD_GDS2526_112_human_MCF-7 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38977
Esotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0722
GPR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30381
CCNQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80697
Cataract, Autosomal Dominant	CTD Gene-Disease Associations	1.0	2.88009
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57431
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06663
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.441
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94744
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84587
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5484_KO_Dnmt_SRP314000	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7748
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.7617
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
protein binding	GO Molecular Function Annotations 2015	1.0	null
Bundle sheath cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.89
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47314
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0682
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.46
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88967
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053229
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89266
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86138
OCIAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42986
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06378
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860509
ML-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.451
lynestrenol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08632
HNF4A	ChEA Transcription Factor Targets	1.0	null
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
molecular_function	GO Molecular Function Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.35775
Parasubthalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13407
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7881
BRD-K56258950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59579
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08242
Gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K22405104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04055
Thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.884
Glyoxysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67006
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.00669
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AKIRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46279
Final leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.432
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129772_2_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chloroplast ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.224
intermediate filament-based process	GO Biological Process Annotations 2015	1.0	null
BRD-K74198088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53326
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78154
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.31538
PITHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5925
BRD-K74677971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10954
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61317
Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30245
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.56234
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35132
NCIH2342	CCLE Cell Line Gene CNV Profiles	1.0	1.78271
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A430-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.134392
HS611T	CCLE Cell Line Gene Expression Profiles	1.0	1.60289
cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
S1P_Deficiency_GDS3654_521_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Epididymal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0094
intermediate filament cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
CCDC186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6349
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28257
Oculocerebrorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
FOXP1	ChEA Transcription Factor Targets	1.0	null
addition	GeneRIF Biological Term Annotations	1.0	null
BRD-K21732483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11531
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04883
SNU503	DepMap CRISPR Gene Dependency	1.0	2.07835
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA42-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MCRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78955
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
ARMCX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48445
MYOD1	ENCODE Transcription Factor Targets	1.0	null
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3114
BRD-K69624346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44255
SVIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17533
Perturb_1758_KO_p300/Tet2_SRP250516	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.31383
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.567
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35265
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	1.8172
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52974
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38816
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938074
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10718
CCND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42573
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Sporophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
myopia	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14741
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02044
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_16737_KO_Rag2/Il2rg/Notch3_SRP220745	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.06241
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13784
BRD-K37790543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65801
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73701
SUDHL4	CCLE Cell Line Gene Expression Profiles	1.0	1.5375
BRD-K75038114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08165
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19835
progressive cataract	HPO Gene-Disease Associations	1.0	null
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65334
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.936247
LYSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05651
Exoribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
Seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.069
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17821
BICR78	DepMap CRISPR Gene Dependency	1.0	2.15831
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17772
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21873
RNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09188
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00805
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.772964
BRD-K06087483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28794
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02635
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02724
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8726
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58561
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.068789
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57156
Acute Myeloid Leukemia_LAML_TCGA-AB-2869-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE254155_1_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.59467
MKN28	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71477
plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.34883
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
QSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70651
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.633
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.8634
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.188278
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.054
BRD-K09583061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07491
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K59865704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44267
LASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75919
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09578
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.07816
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48672
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74795
BRD-K89687419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19132
SSBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9576
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50031
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11617
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35196
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51801
Tapetum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bacterial microcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.646
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25465
Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.5
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6291
SCS214	DepMap CRISPR Gene Dependency	1.0	2.10652
PMC5794192-ppat.1006868.s001.xlsx-S1B_Table-S1B_Table_Differentially_expressed_genes_between_IRF8-sg2_and_NC_cell_lines_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
ZFYVE27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62777
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48564
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950418
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
hsa-miR-4530	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
C19orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3997
personality disorder	GWASdb SNP-Phenotype Associations	1.0	0.781192
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24677
XBP1_OE_GDS2861_60_human_MCF7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02149
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88841
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1856
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85697
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43119
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10521
CRCGN012_HEPG2_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65631
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3947
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
MCF7	DepMap CRISPR Gene Dependency	1.0	2.92869
WSUDLCL2	CCLE Cell Line Gene Expression Profiles	1.0	1.74481
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9189
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99942
496100530_FWM_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7409
intermediate filament	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71646
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996313
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCTD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47706
NRF2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4689
ZNF217-24962896-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97162
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12129
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64501
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glial cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56921
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
etioplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.802479
RCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96834
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI 8226	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
GSE155305_3_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27339
acute leukemia	GWASdb SNP-Disease Associations	1.0	0.55923
Plastid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.139
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.23289
MZT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38439
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.73945
cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.704764
system process	GO Biological Process Annotations 2015	1.0	null
Chloroplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.879
TTC30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89743
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836825
Eye accommodation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.233
19636063-TableS6	GeneSigDB Published Gene Signatures	1.0	null
Perturb_12890_KD_Tet1_SRP151818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.62298
MOLP8	CCLE Cell Line Gene Expression Profiles	1.0	1.37205
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84451
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09131
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20969
Formate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4936
BRD-K24748087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20475
BRD-K05057860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00153
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36324
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67181
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.93617
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.959246
BRD-K56034970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74042
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15896
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55291
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31929
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.50114
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74617
BRD-K86237035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07497
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.317
PACSIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15032
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19604
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.48
SLC29A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3003
BRD-K52232548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53454
ZNF143	ENCODE Transcription Factor Targets	1.0	null
HT-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K08205503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79128
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86186
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43449
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25841
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.03333
PDPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20661
PMC11659402-41523_2024_709_MOESM3_ESM.xlsx-Sheet2-Up_genes_in_ESR1_mutant_within_top_10_and_consistent_in_at_least_40_comaparisons_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21842
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43718
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29185
JURKAT	DepMap CRISPR Gene Dependency	1.0	5.70336
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6243
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712139
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7434
Lung adenocarcinoma_LUAD_TCGA-05-4417-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4166
BRD-K26063034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74349
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879132
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33755
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832131
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15942
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.36086
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48307
BRD-K61432982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38263
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86899
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
ZFP36_Deficiency_GDS2456_707_mouse_Fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1097
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11886
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8003
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.5
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7778
UACC62	CCLE Cell Line Gene CNV Profiles	1.0	1.60435
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
n-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.344556
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC39A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42142
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
Etioplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
visual perception	GO Biological Process Annotations 2015	1.0	null
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1586
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.441
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.7262
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9398
major depressive disorder	GWASdb SNP-Disease Associations	1.0	0.674941
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889468
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7219
BRD-K04883778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3421
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K84052780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11075
Sporulated oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
COX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64307
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938074
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36312
LBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56337
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85919
CRCGN008_HEPG2_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0945
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.589295
BRD-K29469525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49832
intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.802479
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14801
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
yy2_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.023784
Nrf2_deficiency_GDS3406_156_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EB2	GDSC Cell Line Gene Expression Profiles	1.0	1.869
Heterocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.788
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.312
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50921
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	3.10024
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.633
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986831
RNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95184
cellular component organization	GO Biological Process Annotations 2015	1.0	null
BRD-K41311678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22504
Aniridia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.869
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24428
PC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49906
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP1R13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36815
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920757
membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48728
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30155
DOHH2	CCLE Cell Line Gene Expression Profiles	1.0	1.39166
BRD-K35407043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23364
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26126
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67201
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90335
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.706
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04732
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
thiamphenicol-glycinate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27882
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.045
CCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
depression	GWASdb SNP-Phenotype Associations	1.0	0.57836
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
IGSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42617
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2616
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956082
CRCGN012_HEPG2_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11868
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96839404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37207
FTH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01361
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
sw13	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
H3K36me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.42637
Cyanelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.117
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78622
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17092
Prothylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
Myopia	DisGeNET Gene-Disease Associations	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mRNA_EP400_22196727	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
Perturb_1757_KO_p300_SRP250516	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.34614
BRD-K71538933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41925
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2551
OVCAR-8	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43056
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82812
Plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.072
CRCGN013_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44726
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03171
Uveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.712351
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.68803
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_chimp_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.12117
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
MLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53728
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.35276
BRD-K63864310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57715
chlorpropamide-5391	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18657
Perturb_10638_Mut_Cryaa_SRP104440	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.22686
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K14250524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97371
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96105
P2RX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01295
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02691
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.412
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:F10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81985
SHMAC5	DepMap CRISPR Gene Dependency	1.0	2.1205
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.791
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14041
lens epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.41353
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26057
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07302
CLPP_KO_GSE40207_388_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78915
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100583_PCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.74226
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40084
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75641
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22508
only	GeneRIF Biological Term Annotations	1.0	null
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.5
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
Pierson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
Plastid small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.953
TTC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43999
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65365
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.37405
ER to Golgi transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20353
BRD-K60337438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54156
leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447576
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31259
ZNF217	ChEA Transcription Factor Targets	1.0	null
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49678
BRD-K64770897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03231
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05079
Epidermolysis bullosa simplex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17635
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02369
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15690866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1583
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
Cataract	DisGeNET Gene-Disease Associations	1.0	null
BRD-K59205024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.207
BRD-K53489056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19792
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90195
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53464
MOTN1	CCLE Cell Line Gene Expression Profiles	1.0	3.40813
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
VCAP	DepMap CRISPR Gene Dependency	1.0	3.65609
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04517
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6048
Pavement epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K54637865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07628
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58818
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57822
Pathologic nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
Thiazole synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.639
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
PSII associated light-harvesting complex II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.673
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.743986
Epidermolysis bullosa simplex localized type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.354
oxetacaine-1484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7227
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05569
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4486
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41293
provided	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53464
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K25176380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25976
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07823
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38427
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0243
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899454
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5921
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52867
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22774
17555561-Table2	GeneSigDB Published Gene Signatures	1.0	null
proton-transporting two-sector atpase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.497015
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.073
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
proton-transporting two-sector atpase complex, catalytic domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.577581
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:F10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1839
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14468
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18131
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59897
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Protonema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.152
Methane monooxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
vincamine-3865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT	GDSC Cell Line Gene Expression Profiles	1.0	2.50077
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837993
Phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.6
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.47233
Dried cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92273
Thylakoid light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.665
Perturb_8538_KO_Notch2_SRP152804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.3872
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60717
ECC10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70638
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15745
region	GeneRIF Biological Term Annotations	1.0	null
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05411
eye	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
TRAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69222
HEV_60Day_None_GSE53731	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.27603
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fbxl10_OE_GSE34691_579_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
protein complex	GO Cellular Component Annotations 2015	1.0	null
Apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
BRD-K05357297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53895
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75869048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13573
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1217
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K49473928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28413
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TM6SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.53771
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897749
BRD-K64577556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27056
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.078
BRD-K36798110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22276
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Nearest_Ensembl_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94047
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05346
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.44748
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.949118
Macrogamete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92412
MMAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23527
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7817
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09381
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
PKNOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01818
HSD11B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2762
CTCF	ENCODE Transcription Factor Targets	1.0	null
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17285
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Plastoglobule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.114
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23769
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25335
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.110114
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90523
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908036
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9849
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950499
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7121
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45422
Bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07343
EZH2	ENCODE Transcription Factor Targets	1.0	null
Axenfeld-Rieger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
KDM5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36686
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.944247
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14656
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.165927
Chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.369
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24307
CRCGN013_HEPG2_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27501
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5181
Deprivation amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.3992
BRD-K68663367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1085
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.084
CESS	GDSC Cell Line Gene Expression Profiles	1.0	1.41748
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29922
BRD-K27991961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6539
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34454
SATB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18576
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00574
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68062
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.38079
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29305
hsa-miR-4330	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Etioplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.398
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4663
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.567
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
MT-ATP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
b16a	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.47625
CA46	CCLE Cell Line Gene Expression Profiles	1.0	1.58129
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.41082
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02556
OGDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.757
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07343
inner CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964309
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972686
Lung adenocarcinoma_LUAD_TCGA-55-8092-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thylakoid light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.82321
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.131702
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21672
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7951
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40851
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36121
SLC7A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32947
chinese	GeneRIF Biological Term Annotations	1.0	null
NCIH69	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34602
EIF4ENIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77114
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863551
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92937
Emery-Dreifuss muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
chr3_133470018_CT_C_b38	GTEx eQTL 2025	1.0	1.4806
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.922672
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
Plastid ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.073
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Iris disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.912
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065725
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.044674
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.03492
final leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.97285
BRD-K29138092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19392
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836825
supramolecular fiber organization	GO Biological Process Annotations 2023	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Perturb_5825_KO_Pax5_SRP185455	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K31462164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28499
COX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07343
BRD-K52335877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27948
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5883-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92193
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7392-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56428170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14588
susceptibility	GeneRIF Biological Term Annotations	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.659215
Vitreous humor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.1803
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
PMC11659402-41523_2024_709_MOESM3_ESM.xlsx-Sheet2-ESR1_mutation_E2_Co-UP_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071234
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35627
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52051
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
ZNF250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75837
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925767
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18299
REV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68429
CLIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64742
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54717
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.42221
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67705
cellular process	GO Biological Process Annotations 2015	1.0	null
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35978
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U-698-M	GDSC Cell Line Gene Expression Profiles	1.0	1.86993
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.123
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26684
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Gene_Name_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20235
SW 527	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.888648
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78029
Etioplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1796
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.94228
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.16159
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94292
RL7	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
ODR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00772
RDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38263
Posterior polar cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.71
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96769
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
DDAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.388
CRCGN015_MCF10A.TP53.M_24H:B24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58725
ATP1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66956
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67931
Metaplasia	CTD Gene-Disease Associations	1.0	1.09436
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.15376
GET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AP4B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83632
sign	GeneRIF Biological Term Annotations	1.0	null
mode of inheritance	HPO Gene-Disease Associations	1.0	null
YY2_KD_GDS3788_490_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K14442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12265
GJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33669
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54134201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60012
LRFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56189
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.710909
b800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.1803
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4052
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6481-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84995
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5636
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30878
CRCGN015_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3945
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01095
BRD-K94465870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21619
Plastid chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.356
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.236688
psi associated light-harvesting complex i	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.804313
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05381
Acute Myeloid Leukemia_LAML_TCGA-AB-2860-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71567
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10279
ACOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07038
HEL	DepMap CRISPR Gene Dependency	1.0	3.04592
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
BRD-K87073572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.703
NUGC-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.97965
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.446
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56362
Perturb_4531_KD_Senp6_SRP060878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.96115
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96434
496100475_TCx_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00308
hsa-miR-4768-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.88
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27855
BRD-K85292767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63305
SW48	DepMap CRISPR Gene Dependency	1.0	3.79488
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.16068
Leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
Plastid thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.592
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
BRD-K43261169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19596
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6771
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.043384
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16899
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ferredoxin-thioredoxin reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.31
HDAC6	ENCODE Transcription Factor Targets	1.0	null
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.624
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30567
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.256793
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4215
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50587
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.38516
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17589
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21402
SPI1	ChEA Transcription Factor Targets	1.0	null
True leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
Palisade parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
KLF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58137
EW-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ONDA8	DepMap CRISPR Gene Dependency	1.0	2.01299
UGCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8625
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.39085
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863551
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829636
BRD-K37019305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00949
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2481
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.643669
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	2.48495
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22508
Lens epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.805
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.882385
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7355
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.94833
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18932
BRD-K78658063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20692
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66841
Acute contagious conjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17762
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03403
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_4829_KD_Rrp40_SRP150410	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.04929
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12427
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	2.01636
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
lamellar	GeneRIF Biological Term Annotations	1.0	null
phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.07172
typical	GeneRIF Biological Term Annotations	1.0	null
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8048
ERMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79057
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
ELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76532
APPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92487
organelle part	GO Cellular Component Annotations 2015	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.053055
PWWP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01733
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50547
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0888
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77914
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lens cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.796
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63588
HNRNPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45877
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.543
ETNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33914
protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.229176
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33087
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
natc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.558042
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.305
Chloroplast thylakoid membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.631
BRD-K81501934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16714
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2099
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28471
VMRC-RCZ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950418
FOXO1-25302145-T-LYMPHOCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5801
CTB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Raji	GDSC Cell Line Gene Expression Profiles	1.0	1.52059
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97213
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78488
EVA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85231
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0493
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06496
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8727
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254239
BRD-K03937692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25632
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33146
Rosette	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.748
SP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836579
IMR-5	GDSC Cell Line Gene Expression Profiles	-1.0	-2.05091
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26497
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66679
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal vision	MGI Mouse Phenotype Associations 2023	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12271
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
MEIOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18713
BRD-A73150064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39923
BRD-K76350099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8219
ONS-76	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44866
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77463
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGF1_OE_GDS3484_538_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71806
BRD-K75007044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19698
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2023	1.0	null
hsa-miR-3173-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.918778
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.973
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
leukemia	GWASdb SNP-Disease Associations	1.0	0.341115
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93167
Rubella	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09584
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96248
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
A3KAW	CCLE Cell Line Gene CNV Profiles	-1.0	-2.78131
Chloroplast thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.594
GSE125219,GSE125221_5_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.6145
BRD-K41603100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52587
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the lens	HPO Gene-Disease Associations	1.0	null
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0198
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5816
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961653
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56469
BRD-A05828965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09247
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
EP300	ChEA Transcription Factor Targets	1.0	null
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62185
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06663
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9006
cataract	HPO Gene-Disease Associations	1.0	null
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54673
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Transfer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
Kidney Chromophobe_KICH_TCGA-KN-8435-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03991
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16522
NCOA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59186
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.078522
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65472
SNX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8629
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43035
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2844
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.68885
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7688
SLC17A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10644
vitreous humor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325335
Polymeric cytoskeletal fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Perturb_4819_KO_Apex1_SRP193096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.64166
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32859
disulfiram-5729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ERGIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62216
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95572
Charcot-Marie-Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
organelle subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.29371
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2682
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55987
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTHFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89327
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56874
MYC_KD_GSE22139_685_human_medulloblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MRFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
Exfoliation syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.01455
RCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47132
Respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
Leaf primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
DSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60181
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.42885
FOXP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90057
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.09407
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26672
BRD-K78612514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09856
case	GeneRIF Biological Term Annotations	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21248
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.987099
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.82943
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9765
Perturb_9714_KO_miR34a_SRP058984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.62333
Hmgn1_KO_GDS5010_405_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ATM_01_29	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62012
NCIH2030	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6131
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
cytoskeleton	LOCATE Curated Protein Localization Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
BRD-K51787437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95831
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58573
Small_Intestine-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	1.38522
Perturb_7991_KO_Dnmt3a_ERP107945	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.19189
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50464
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.34395
INA6	DepMap CRISPR Gene Dependency	1.0	4.90022
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58657
REST	ENCODE Transcription Factor Targets	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.41445
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836825
BRD-K97263385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74685
bp86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
ARHGAP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54712
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ayme-Gripp syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PNPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94019
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11132
BRD-K95385525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08572
Lens	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.368
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49534
Granum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.022
RAB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38721
vascular disease	GWASdb SNP-Disease Associations	1.0	0.065397
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75502
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.945118
BRD-K28305165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02618
BRD-K34169251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05841
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
BRD-K11404512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46241
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55711
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.77999
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02377
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8762
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53493
Leaf tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Gerontoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.234
Spindle cell rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
SKES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.7627
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5955
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39441
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KYSE180	CCLE Cell Line Gene CNV Profiles	1.0	1.62724
BRD-K64992851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90977
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052729
NFIC_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.368
BRD-K29183384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03458
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23889
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K19712135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03013
abnormal cell cytoskeleton morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MJ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.58648
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14327
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.961368
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.81685
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47256
Plastid thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.872
RI1	CCLE Cell Line Gene Expression Profiles	1.0	1.52594
Chloroplast small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.953
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04935
CRCGN008_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2885
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53081
PMC4721115-13148_2016_171_MOESM1_ESM.xlsx-SOM_Table_8-Gene_Symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24687
TMEM59L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54809
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2081
EEF1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47438
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30705
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.76519
micropexophagy-specific membrane apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.9118
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K38493972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18458
BRD-K11610091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20819
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0041
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904387
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07893
BRD-K80296876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37354
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01480	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.912331
Adult Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05937
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15578
heterogeneity	GeneRIF Biological Term Annotations	1.0	null
BCL9L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66214
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47289
PMC4021073-1471-2407-14-278-S4.xlsx-Sheet1-Supplementary_Table_S5_Genes_with_GATA3_ChIP-seq_peak_within_10kb_from_transcription_start_site_TSS_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NR1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08645
DND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06314
LAN-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63357
BRD-K58219783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02515
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
sporophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09341
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97157
MYOG	ENCODE Transcription Factor Targets	1.0	null
LRRC4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19367
TIMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45018
CLPP_KO_GDS4791_374_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Sutural Cataract	DisGeNET Gene-Disease Associations	1.0	null
Exudative vitreoretinopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
CORL23	CCLE Cell Line Gene CNV Profiles	1.0	2.85297
DALRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76292
Alexander disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
FOXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68254
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32591
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21874
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.825187
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.131919
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52313
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845851
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.703217
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.460692
Chloroplast ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.091
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863551
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3388
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6058
Nucleomorph	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
Thrombocytopenia	DisGeNET Gene-Disease Associations	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4045
BACE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45814
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70192
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831715
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GRANTA519	CCLE Cell Line Gene Expression Profiles	1.0	1.45073
CHSY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47385
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.35856
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92529
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.110074
pedigree	GeneRIF Biological Term Annotations	1.0	null
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50583
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
proton-transporting atp synthase complex, catalytic core f(1)	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.577581
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79858
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82693
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.82196
BRD-K12411112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42464
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58585
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940407
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-IRF6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90701
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33198
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.46046
GSE242167_1_v_2_cd40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6508
CRCGN015_HEPG2_48H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4485
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.4285
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03205
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.657866
BRD-K62541003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28671
ZNF362	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55051
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38728
CGAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64727
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.663555
chloroplast thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.66538
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.094
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6211
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71567
BRD-K70237115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04751
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.65212
congenital cataract	HPO Gene-Disease Associations	1.0	null
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87973
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl571_gds4063	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K93268593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04643
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
GSE98755,GSE98756_3_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6998
Perturb_10227_KO_Dmnt1_SRP305326	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.87778
RABIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07103
Organelle envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.27
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12585
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989401
BRD-K62170825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17891
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10736
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
BRD-K68458302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02858
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
lens fiber cell development	GO Biological Process Annotations 2015	1.0	null
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57094
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_11951_OE_MYC_SRP355809	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PANC0213	CCLE Cell Line Gene CNV Profiles	1.0	1.37303
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5299
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86407
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52317
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32533
CTNNB1_OE_GDS4449_352_mouse_Embryonic kidney from E12.5 embryos (-catGOF-UB mutant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19012
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CHST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6506
LZTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77038
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-2.6953
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918948
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053747
Senile cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.273
K562	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37783
RERF-LC-MS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.851149
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.459
Olfactory placode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
Perturb_4568_KO_Prmt1_SRP178236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.20903
deletion	GeneRIF Biological Term Annotations	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0707
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12441
ADRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08746
Lung adenocarcinoma_LUAD_TCGA-44-7672-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99835
NCOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
developmental maturation	GO Biological Process Annotations 2015	1.0	null
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
hyperferritinemia-cataract syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20097
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824793
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95526
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38245
Ebl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	0.836149
CYP2R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29977
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10886
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.883893
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79438
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34264024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04965
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04603
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69777
POGLUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80027
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11055
leukemia	GWASdb SNP-Phenotype Associations	1.0	0.23203
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.30386
intracellular part	GO Cellular Component Annotations 2015	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5385
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02635
hitherto	GeneRIF Biological Term Annotations	1.0	null
BRD-K09511124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43406
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926167
UBE2Q1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49891
LS411N	DepMap CRISPR Gene Dependency	1.0	9.20676
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0116
RND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41517
BRD-K72602058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10094
NFE2L2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21478
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NPY5R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35807
Leaf bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
BRD-K90625628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39521
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836825
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
levocabastine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94125
PRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4892
refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.547807
Retinoschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1627
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.78235
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.567
BRD-K67896259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47763
GSE188884,GSE189078_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sensory perception	GO Biological Process Annotations 2015	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65909
venous abnormality	GWASdb SNP-Phenotype Associations	1.0	0.754273
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08279
senescence-associated vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
CUEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17697
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.860852
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04341
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306083
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.666402
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.386
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3969
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12007
BRD-K39348592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21035
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K16852474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01892
Oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.217
496100600_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48596
BRD-K59392325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70415
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551298
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2264
intermediate filament	GO Cellular Component Annotations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.20922
SYT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8566
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829319
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50119
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.568547
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37412
hsa-miR-3199	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.973
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03106
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2505
Amyloplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87546
eye and adnexa disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K99028283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43371
RH41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77642
BRD-K51087734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11988
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80479
BRD-K46603043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84765
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.864
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
Salivary_Gland-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	0.670831
Perturb_15358_KO_Tfap4_SRP212619	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32071
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73377
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.996217
Perturb_9437_KO_Mapk14_SRP308388	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.67777
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.292651
BRD-K82681356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24174
BRD-K98953346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01149
BRD-K46269666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00778
cataract 12, multiple types	OMIM Gene-Disease Associations	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.054048
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.01
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.83939
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85904
PMC4721115-13148_2016_171_MOESM1_ESM.xlsx-SOM_Table_9-Gene_Symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41909
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0722
Hamartoma	DisGeNET Gene-Disease Associations	1.0	null
structural constituent of eye lens	GO Molecular Function Annotations 2015	1.0	null
cytochrome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.13537
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chloroplast nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.682
EBC1	DepMap CRISPR Gene Dependency	1.0	3.0996
OXCT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67987
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10679
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25629
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.436
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2657-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138024_2_v_3_rgs4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-609	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
Phacogenic glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0211
Immature cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05607
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3488
protophloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.163076
KIAA2013	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22077
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33189
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.97383
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CUX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68696
BRD-A22502911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25933
NUP214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38092
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.97868
BRD-A92729194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07559
KMS26	CCLE Cell Line Gene Expression Profiles	1.0	1.9422
HOXC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43858
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32364
HCC2935	DepMap CRISPR Gene Dependency	1.0	2.04911
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09803
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K01009153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10216
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910943
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
PCGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03756
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8445
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45264
BRD-K98578493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54456
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97829
Plastid nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.665
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845099
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922112
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-A71962374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11796
earliest	GeneRIF Biological Term Annotations	1.0	null
BRD-K30921693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5254
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54241
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57488
abnormal anterior eye segment morphology	MPO Gene-Phenotype Associations	1.0	null
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08294
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20682
CRCGN017_MCF10A.WT.HP_24H:K21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1789
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
phycobilisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.40186
BRD-K89805341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22209
SARS-CoV MA15_Day4-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.98949
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70315
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
structural molecule activity	GO Molecular Function Annotations 2015	1.0	null
Prestwick-664-6033	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80699
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69858
WWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89614
BRD-K41538715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13129
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.555973
CYRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49384
BRD-K01367715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14193
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11422
GLRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24258
Cataract, Autosomal Dominant, Multiple Types 1	CTD Gene-Disease Associations	1.0	2.88009
lymphoblastic leukemia	GWASdb SNP-Disease Associations	1.0	0.4117
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95228
reported	GeneRIF Biological Term Annotations	1.0	null
MIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88608
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K10540354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79757
recessively	GeneRIF Biological Term Annotations	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41293
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63303
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07578
Chloroplast photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25915
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851392
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043624
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA1	DepMap CRISPR Gene Dependency	1.0	2.2432
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.2321
NCIH1755	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37241
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
Plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.696
Flag leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.456
BRD-K59843356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10184
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07083
Terminal loop	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Childhood Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
abnormal vision	MPO Gene-Phenotype Associations	1.0	null
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12232
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
16207250-TableS2	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7969
ysutural	GeneRIF Biological Term Annotations	1.0	null
ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118201
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00154
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869449
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48075
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	1.24727
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3153
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852647
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27386
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3206
Iris dilator muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
EBF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53906
hsa-miR-4422	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3101
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.9913
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Human lens epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.496
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00722
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5403
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.366
SPAG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30947
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16256
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.059818
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.496
SOX7_01_299	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.74059
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21927
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ChaGo-K-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.489
BRD-K83645749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26606
artery disease	GWASdb SNP-Disease Associations	1.0	0.091046
acute leukemia	GWASdb SNP-Phenotype Associations	1.0	0.357352
DOHH-2	GDSC Cell Line Gene Expression Profiles	1.0	1.6713
SNAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34312
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.655
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_SMAD1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bolting stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
FANCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61137
plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Perturb_3388_OE_Dhx37_SRP201770	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.36789
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933099
RERFLCKJ	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92363
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
alexander disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.772479
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29499
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8583
BRD-K05509844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74193
KMS20	DepMap CRISPR Gene Dependency	1.0	4.59856
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053152
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60234
JHH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62363
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.885773
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0273
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04373
Leaf base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48618
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.86307
Peters anomaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.078
present	GeneRIF Biological Term Annotations	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.579251
iris disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.337975
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66205
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.616
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.997425
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35873
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.225902
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886973
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17503
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59704
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11324
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.756564
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.579251
PREB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51965
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27047
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
BRD-K69087429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59324
TTT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.17
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31685
increased corneal light-scattering	MPO Gene-Phenotype Associations	1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38134
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29675
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.048654
Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0707
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77J-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17171
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06801
Photosystem I reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.073
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE203308_6_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BDCM	CCLE Cell Line Gene Expression Profiles	1.0	1.8298
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12636
AATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51002
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.01373
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Glial filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4733-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23604
GNG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64333
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11744
Shoot base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
PMC11244912-media-3.xlsx-Sheet2-ESR1_mutation_E2_Co-UP_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
MEIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70747
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8584
KARPAS-422	GDSC Cell Line Gene Expression Profiles	1.0	1.85686
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00805
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73962
BASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21712
Photosystem II oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.525
GAK	GDSC Cell Line Gene Expression Profiles	1.0	1.48233
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64593260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27764
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223662
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.715902
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73807
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42833
formation	GeneRIF Biological Term Annotations	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62008
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8932
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0243
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Chloroplast thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.89
LRP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44991
photosystem ii oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.63242
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5162-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.218
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.858392
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28769
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26237
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54262
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41124
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.784
LOX-1_OE_GDS4262_435_human_HAECT - aortic endothelial cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00029
C19orf73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67323
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10858
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15644
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5886
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850807
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00905
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78327
BRD-K20807411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11646
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	3.24978
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.007
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8322
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62659
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14762
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4alpha_KO_GDS1916_168_mouse_Embryonic liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DYRK1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48869
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
Perturb_11952_OE_MYC_SRP355809	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K42873980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10763
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76864
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00631
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3441
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30612
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
chloroplast part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.35704
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0955
lens	GeneRIF Biological Term Annotations	1.0	null
ZNF217-24962896-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE218580_1_v_2_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.67592
GUSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42976
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74637
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40088
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.70303
BRD-K47415214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76671
BRD-K40011635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21611
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36273
BRD-K77173942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7562
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.3376
Kahrizi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.897
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66944
RNF216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78593
CERS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93716
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11138
CRCGN013_HEPG2_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0142
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.30139
RAB11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40808
OCI-AML5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4229
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
Presbyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.316
TYW3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89997
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95688_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.174943
HSC3	DepMap CRISPR Gene Dependency	1.0	2.1871
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07952
BRD-K54837058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09681
BRD-K06492185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76179
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
RTN4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55911
intermediate filament cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3781
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82052
BRD-K22534934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08007
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8518
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48982
fashion	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.07615
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4134
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BFTC-905	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
mood disorder	GWASdb SNP-Disease Associations	1.0	0.321361
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9545
Chl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.167
JUP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68334
JHOC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58072
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	2.38787
GSE160293_2_v_4_celf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
defects	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04706
BRD-K68743686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41547
Cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22616
lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.43663
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1643
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZCCHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15294
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.44516
BRD-K79067166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62304
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.30807
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93785
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08723
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Intermediate filament cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BACH1	ChEA Transcription Factor Targets	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18125
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34021
inner CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22714
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47265
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51202
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08863
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
Thymus-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	7.75753
BRD-K53814023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3808
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64419
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61242
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3597
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37467
NB4	DepMap CRISPR Gene Dependency	1.0	3.40991
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9935
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
UBE2G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88604
abnormal lens morphology	MPO Gene-Phenotype Associations	1.0	null
Gastrodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
MOPC-315 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
PCDHB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56283
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.45156
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ocular motility disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48697
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86843
ARPP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30207
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103428
Epidermolysis bullosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9166
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
acute lymphocytic leukemia	GWASdb SNP-Disease Associations	1.0	0.55923
BBC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44711
BRD-K04468899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4402
stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118201
Retinal detachment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.70596
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74709
PROX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6782
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
ZNF862	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.118
EW16	DepMap CRISPR Gene Dependency	1.0	3.39539
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35028
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70486
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.817
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5111
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62147
congenital	GeneRIF Biological Term Annotations	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37308886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11939
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96915
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7594
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.07947
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8515
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83227
Synganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.097
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23659
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17539
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32958
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17525
eye disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.41979
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20518
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2719
varicose veins	GWASdb SNP-Phenotype Associations	1.0	0.754273
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10009
BRD-K17965071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68868
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.511
Keratin, type I	InterPro Predicted Protein Domain Annotations	1.0	null
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.601
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.2288
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4148
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15697
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23308
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21949
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25057
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7337
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.304
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79516
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
Intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.111
PMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47788
Lamin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.984026
BRD-K73387470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16595
NDUFA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18045
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827484
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.5
Isoamylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.946
H3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23516
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.632878
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
stoma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282837
SNU840	DepMap CRISPR Gene Dependency	1.0	7.41622
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Marijuana Abuse	DisGeNET Gene-Disease Associations	1.0	null
BRD-K34405227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07079
b875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.320826
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63932
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09287
YIPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26022
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53703
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.29877
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96848
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66584
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68956
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911934
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3987
CER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04528
BRD-K37592272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00963
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.8313
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11462
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92403
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0562
Perturb_1721_Mut|KO_Srsf2_SRP368113	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.4311
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4243
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03121
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836825
Magnesium chelatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.676
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70038
Pyrenoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.834
Retinitis pigmentosa 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
HMCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19971
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2267
TCEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70216
BRD-K62892366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.164
BRD-K75710654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39239
chloroplast thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.63182
Irido-Corneal Dysgenesis	DisGeNET Gene-Disease Associations	1.0	null
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95734
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.069052
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAP1GAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37367
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.648138
Photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.863
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0707
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.64667
CRCGN009_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02347
Intermediate filament	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Acute Myeloid Leukemia_LAML_TCGA-AB-2964-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IQSEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63768
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43495
BRD-K90877053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90902
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6743
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054417
pentolinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37539
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74604
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09468701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10566
B4GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67524
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941717
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.966379
vision/eye phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K11666748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0892
locus	GeneRIF Biological Term Annotations	1.0	null
HCT15	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.37471
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Vesiculobullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837993
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1865
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
BMPR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71505
Cef cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.982727
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20525
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.71067
FOXP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27859
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29499
NUDT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20843
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85274
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049305
Perturb_4533_KD_Uba2_SRP060878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.38454
granum	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.638434
cause	GeneRIF Biological Term Annotations	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908801
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotype	GeneRIF Biological Term Annotations	1.0	null
Lens nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.843
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07807
BRD-K54023716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34255
TRIM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89181
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37492
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0002
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
SP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07507
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06801
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0874
West Nile encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
BRD-K95129711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06076
Lens epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.57
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Bacterial Infection_Peripheral blood mononuclear cell_GSE3026	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.82613
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2025	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38106
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.9939
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	2.00182
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.467
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87239
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49523
PABPC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29408
CAMK2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87096
MET_knockout_261_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.69509
MCM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49789
gfi1b_22201127_amulv_gof_mouse_gpl6246_gds4302	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.938077
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.27186
Alport syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35872
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
sensory perception of light stimulus	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.02234
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.54805
Wes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6286
Syndromic microphthalmia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
GRINA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37062
Cataract 32 multiple types	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GUCA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81151
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45945
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14639
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.33329
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20466
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32923
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00478
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.278778
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12497
uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.107674
kidney disease	GWASdb SNP-Disease Associations	1.0	1.079
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11968
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77917
neurological system process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.63464
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05647
FEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52078
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GALNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53125
BRD-K66700691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54542
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9792
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.04879
ZNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7403
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0722
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35324
supramolecular fiber organization	GO Biological Process Annotations 2025	1.0	null
BRD-K68608492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23535
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25895
Intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.114
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02729
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15494
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Secondary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29344
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.7
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.62007
Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07365255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57474
dg1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
ANKFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74456
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Mesophyll	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.232
Uterine Carcinosarcoma_UCS_TCGA-ND-A4W6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11762_KO_Irgm1_ERP020504	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.33173
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1464
pitx3	GeneRIF Biological Term Annotations	1.0	null
GSE113106_0_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
SP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36225
Photosystem II reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.908
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835563
EWS502	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42225
STC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46208
Fbxl10_OE_GDS4788_580_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MEIS1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50303
Microphthalmos	DisGeNET Gene-Disease Associations	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18729
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22672
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.888648
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861375
abnormal eye morphology	MPO Gene-Phenotype Associations	1.0	null
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
BRD-K27028848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04581
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RDES	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48703
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55145
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.931936
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042789
leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61699
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03258
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.109037
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.014
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4157
Lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.155
Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.085974
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04824
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bilateral Cataracts (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.73765
BRD-K29684372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65663
Catalepsy	DisGeNET Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56035
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74649
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29185
ML-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8829
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836825
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1576
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42145
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
all	HPO Gene-Disease Associations	1.0	null
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81232
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35103
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06737
CD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49011
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01039
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.505
RBBP5	ENCODE Transcription Factor Targets	1.0	null
BRD-K34018387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28048
known	GeneRIF Biological Term Annotations	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4158
piretanide-6828	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HNRNPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84097
Eiii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14724
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30239
496100565_FWM_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39837
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907937
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67623
epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194024
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35746
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84995
Perturb_15641_KO_Shh_ERP023558	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.78807
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51062
GSE116242_0_v_1_olig2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFE2L2	ChEA Transcription Factor Targets	1.0	null
photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	3.14799
PLXNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41489
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8855
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75812
ERBB2_knockdown_231_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.95345
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
BRD-K67931592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08738
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87012
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.236688
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27206
serine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
CAPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39215
estradiol_homo sapiens_gpl6947_gse27375	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33752
SUDHL10	CCLE Cell Line Gene Expression Profiles	1.0	1.6409
globe disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Phycobilisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.178
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
GPATCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74828
Nuclear lamina	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
BRD-K54593730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02436
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83519
PMC11225427-13058_2024_1861_MOESM2_ESM.xlsx-Supplemental_Table_S4-Supp_Table_S4_AR_mediated_PGx-eQTL_genes_and_associated_with_all_GWAS_traits_from_GWAS_catalog_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_15774_KO_Uxt_SRP240277	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
opacity	GeneRIF Biological Term Annotations	1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.85688
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71238
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03121
abnormal lens fiber morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
18387200-Genes	GeneSigDB Published Gene Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3329
SORD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72191
Glume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
RELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38228
Mature stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.522
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965605
CHST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56766
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.5
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08259
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
NOVA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3322
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87314
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56895
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.142294
type iii intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.506757
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.92262
15691381-Table5	GeneSigDB Published Gene Signatures	1.0	null
WDR82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43672
BRD-K90686530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07457
NatC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
NP5	DepMap CRISPR Gene Dependency	1.0	2.46961
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.52866
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073699
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27621
FRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12802
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0722
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22812
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75335
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13377
ZFPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51232
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68244
GSE182680,GSE182683_7_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HLEC-SRA 01/04 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
psii associated light-harvesting complex ii	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.84224
BRD-K82021299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41794
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10718
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
EIF4EBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84473
cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390799
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04811
ULK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75557
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76989634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37725
Fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.339
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17805
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05939
DDX50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27781
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.639
Superior central nucleus raphe, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38234
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32434
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91476
Storage tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52293
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23416
m.dunni	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.118389
MCIXC	DepMap CRISPR Gene Dependency	1.0	8.24886
Perturb_1420_OE_Aatf_SRP257744	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.02691
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899888
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5972
BRD-K78989575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05327
USP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97911
HNRNPCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8028
ATP5MC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58589
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8444
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.7
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05046
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.184424
Vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.361
oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.108086
oseltamivir-phosphate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3983
isoetarine-2711	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KRAP_Deficiency_GDS3527_566_mouse_Brown adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20375
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.80142
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.970686
BRD-K30312557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82798
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53464
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4256
photosystem ii reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.98195
Mature cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.884
plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.62472
HCC70	DepMap CRISPR Gene Dependency	1.0	2.57688
GSE126402_1_v_6_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7464
BRD-K12396271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37152
intermediate filament	GO Cellular Component Annotations 2015	1.0	null
OVMANA	DepMap CRISPR Gene Dependency	1.0	2.10646
epididymal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.664368
Perturb_1761_OE_Notch1_SRP311399	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47673
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03121
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09578
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2L2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78144
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6327
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14342
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.089
Xylem parenchyma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
BRD-K45860594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26271
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039345
BRD-K05615182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20624
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.831202
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.734249
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4272
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.763617
single-organism process	GO Biological Process Annotations 2015	1.0	null
Filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.592
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04019
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.59896
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90463
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.13143
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.659897
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2205
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56498
Myofibrillar myopathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.363185
KMS11	CCLE Cell Line Gene Expression Profiles	1.0	2.12718
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10679
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13957
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
MATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7278
lung disease	GWASdb SNP-Disease Associations	1.0	0.621951
BRD-K04087396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08722
physiological	GeneRIF Biological Term Annotations	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.53526
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
ABCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95509
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31627
External ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.596
BRD-K76691746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89714
FZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87516
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8589
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12149
BRD-K28429328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63528
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75382
blood	GTEx Tissue Gene Expression Profiles	1.0	1.31251
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.307004
glucose-1-phosphate adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69499
ARV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17518
BRD-K35848924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11023
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13258
SALL4	ChEA Transcription Factor Targets	1.0	null
Photosystem II antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.109
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4284
DAUDI	CCLE Cell Line Gene Expression Profiles	1.0	2.64622
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31929
TP53	ChEA Transcription Factor Targets	1.0	null
Terminal web	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
MKN1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66057
aniridia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.500761
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74737
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34856
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23701005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46894
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32952
BRD-K10412976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67323
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02499
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05884
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94048
Acne_Sebocyte_GSE10432	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.16378
non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70456
Kidney Chromophobe_KICH_TCGA-KL-8340-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00463020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79747
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21758
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
Perturb_15364_KO_Mef2c/Mef2d_SRP064307	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Cataract 11 multiple types	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2748
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MFSD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1398
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84936524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51344
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14295
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.0503
BRD-K27888332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1037
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12219
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
thylakoid part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	3.13002
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78688
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
CTNNB1	ChEA Transcription Factor Targets	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3263
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950418
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mental depression	GWASdb SNP-Disease Associations	1.0	0.43942
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0243
lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065873
Intermediate filament protein	InterPro Predicted Protein Domain Annotations	1.0	null
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
Leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.253
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41511
hematologic cancer	GWASdb SNP-Disease Associations	1.0	0.174943
Cataract 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08646
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17391
abnormality of refraction	HPO Gene-Disease Associations	1.0	null
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
intermediate filament cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Perturb_13644_KD_Trim28_SRP126388	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.52093
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.22945
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8961
NCIH2882	DepMap CRISPR Gene Dependency	1.0	2.44917
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S1-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48598
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.84775
insulin resistance	GAD Gene-Disease Associations	1.0	null
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43319
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52151
BRD-K73479560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47304
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87887
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.003
BRD-K18428988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19036
Organelle subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.445
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07843
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070355
ACTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
Exudative vitreoretinopathy 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.854
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65857
U-266	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K82927098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08419
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K48805623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63209
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20171002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69773
Myofibrillar myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
all	GWASdb SNP-Phenotype Associations	1.0	0.045899
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00725
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36145
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54189
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00903
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46855
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852062
myopia	HPO Gene-Disease Associations	1.0	null
metaphloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170715
GSE100464,GSE100465_0_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.58714
ERA-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSK3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48169
cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.97129
BRD-K21450593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49773
BRD-K95922469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26232
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41161
caused	GeneRIF Biological Term Annotations	1.0	null
miR-142-3p_OE_GSE28456_470_human_Raji cells (B lymphocytes)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Galactokinase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
PMC12152148-41420_2025_2541_MOESM3_ESM.xlsx-AR-IP-DHT_peak-gene-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312957
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.281
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89744
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40508
cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.096188
hsa-miR-330-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K12613826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21187
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04055
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63185
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71812
CLPP_KO_GSE40207_392_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	2.99545
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65792
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE137144_5_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4542
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.975964
esculin-5411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2108
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50792
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81121
Amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.221
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11471
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62354
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13346
TRIAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53637
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.83
BRD-K51278788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10469
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80478
venous insufficiency	GWASdb SNP-Phenotype Associations	1.0	0.754273
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
Stromule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2344
CRCGN014_HEPG2_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01413
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43595
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95491
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.22
PMC11244912-media-3.xlsx-Sheet2-Up_genes_in_ESR1_mutant_within_top_10_and_consistent_in_at_least_40_comaparisons_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
U-266	GDSC Cell Line Gene Expression Profiles	1.0	1.55478
H3K36me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135334,GSE136010_2_v_3_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K54250149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09525
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04882
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985892
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36367
BRD-K87602457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4756
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.069743
NRF2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
proton-transporting atp synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.497015
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40652
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57344
plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.959748
Stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.585
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46302
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09768
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55441
BRD-K93391478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13033
intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.802479
BRD-K02087489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3241
MYOD1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10114
GSE222445_2_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74023
Lung adenocarcinoma_LUAD_TCGA-99-8028-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65441343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45756
hsa-miR-4268	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GI-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.932253
Chromoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.243
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04985
BRD-K84062787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30143
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02169
SPI1-22096565-GC-B-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Human - Fetal Development - L2 - Eye-Lens fibre cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75839
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
UBE2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62004
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.65345
chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.34501
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69814
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30129
HCC15	DepMap CRISPR Gene Dependency	1.0	5.92852
Chloroplast stromal thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.30551
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23663
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45398
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4491
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08753
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.1008
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.747
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21243
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.146505
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45T-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36257
SCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08055
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.960146
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950418
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27833
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36121
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.96557
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79667
BRD-K30895360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32125
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18172
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87806
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18854
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04385
KDM5A-27292631-CHIP-SEQ-BREAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.471
BRD-K57404319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0623
Plastid envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.136
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06663
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46949
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.599112
BRD-K94088690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13869
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83502
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06801
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49584
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62747
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04367
proton-transporting two-sector ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.58
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0506
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53121826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02139
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.5
BRD-K52657580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08928
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
TAT protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.927
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67777
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6103
ITGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9817
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K44643967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55321
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0876
BRD-K59159023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09628
abnormal lens fiber morphology	MPO Gene-Phenotype Associations	1.0	null
TUNAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52221
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20659
Thyroid	GTEx Tissue Gene Expression Profiles 2023	1.0	7.09859
BRD-K58614056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00998
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38728
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SELENOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35513
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13062
Dinoflagellate hypocone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5274
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6619
496100607_TCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.1688
BRD-K47541706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18448
SOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20545
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
RL	GDSC Cell Line Gene Expression Profiles	1.0	2.2885
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
PIP4P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55512
LPXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17158
CIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23317
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20232
OCUG1	DepMap CRISPR Gene Dependency	1.0	3.10182
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9552
FAM83H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58091
Ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
HMX1_Deficiency_GDS4810_324_mouse_Retinas of C57BL/6J	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cell maturation	GO Biological Process Annotations 2015	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28257
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73954
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110045
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2497
HDAC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1341
cell development	GO Biological Process Annotations 2015	1.0	null
BRD-K38969544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0496
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate filament organization	GO Biological Process Annotations 2025	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.046166
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.052701
Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11324
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.168
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863949
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TMEM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78399
Organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.391
Insulin Resistance	dbGAP Gene-Trait Associations	1.0	0.061034
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25057
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54101
PBX3	ENCODE Transcription Factor Targets	1.0	null
optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.41848
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11071
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7679
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06801
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37007
BRD-K46839342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13353
NCIH2141	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42078
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.907768
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64501
ABHD17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37783
BRD-K40494117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16933
BRD-K61925563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29249
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8637
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39635
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23621
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.38516
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.86
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67227
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
endogenous depression	GWASdb SNP-Disease Associations	1.0	0.674941
HMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57361
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07399
Perturb_16888_OE_Sca17_SRP248035	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.40763
Congenital nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
bfsp2	GeneRIF Biological Term Annotations	1.0	null
BRD-K12665145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10467
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75867
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5049-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.424765
SHISA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53993
NUDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88885
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15831
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77275
Chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.454
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59931
BRD-K23886631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04339
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.54
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25057
SFMBT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6442
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05848
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.950823
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08826
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32965
YY1AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11286
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20722
hsa-miR-548v	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
EDEM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40708
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70542
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55534
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.072409
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66985
MXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98131
CLOCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.27634
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76884
Strabismus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.41587
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.77497
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
MERO14	DepMap CRISPR Gene Dependency	1.0	4.0249
GSE137144_3_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2541
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LSM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55621
Glutamate synthase complex (NADPH)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.217
Alternating esotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.598538
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044505
CBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24475
Chloroplast thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.577
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_H_sapiens_970_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68505
Perturb_4939_KD_Etv5_SRP111429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.39784
intermediate filament organization	GO Biological Process Annotations 2023	1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06663
BRD-K48813201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45877
photosystem ii	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	3.44492
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59125
BRD-K69751974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17733
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840929
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1611
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14693
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6186
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.76329
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
evidence	GeneRIF Biological Term Annotations	1.0	null
GEMIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09384
BHLHE22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37979
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1819
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91066
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.433
Chloroplast chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971165
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior segment dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.984
Lens disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05674
GSE146074_6_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5249-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15068
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
HCC2998	DepMap CRISPR Gene Dependency	1.0	3.25879
SMAD1	ChEA Transcription Factor Targets	1.0	null
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0665
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950418
MINO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8674
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36444
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGR-1	GDSC Cell Line Gene Expression Profiles	1.0	1.59454
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.189812
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5679
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38742
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33088
Supramolecular polymer	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CKAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06772
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26807
PMC6487024-13148_2019_658_MOESM2_ESM.xlsx-S3-ADNP-1_DMRs-Unnamed_11_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.749993
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.29298
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
COLO800	CCLE Cell Line Gene CNV Profiles	1.0	2.45298
BRD-K03214579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17589
GSE221004_3_v_0_prdm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
Perturb_16721_KO_Brca1_SRP094855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.5068
lateral ventricle	HPA Tissue Protein Expression Profiles	1.0	2.04572
BRD-K56336567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22001
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71002
eye	GeneRIF Biological Term Annotations	1.0	null
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52111
personality disorder	GWASdb SNP-Disease Associations	1.0	0.889594
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039204
SF1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K55835264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76741
UBE3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28077
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11462
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
B9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27574
TGFBR2_knockout_295_GSE45968	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.42996
TFAP2C	ChEA Transcription Factor Targets	1.0	null
RHBDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50831
Supramolecular fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TET2_KO_GDS4287_429_mouse_LSK - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.586
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
plastid thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.66417
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	2.26503
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAW/LR5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
Perturb_4528_KD_Chaf1a_SRP060878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.95097
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27012
BRD-K27754030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39339
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
Perturb_15737_KO_Camk2d_SRP281889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.36361
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FGFR3_KD_GSE41035_77_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950418
Lung adenocarcinoma_LUAD_TCGA-50-5045-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
SW1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03794
Retinitis pigmentosa 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
P53_DN.V2	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
PMC9306206-12915_2022_1367_MOESM6_ESM.xlsx-Table_S7_-_JIP-Gene_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60992
Nance-Horan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.501
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.335
Perturb_5104_KO_Ythdc1/Dux_SRP251747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.61065
Cataract 38	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60542
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.765438
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
T3M3	DepMap CRISPR Gene Dependency	1.0	2.8271
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Proplastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.736
ZXDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3455
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.34637
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.94662
Seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.227
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5595
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42601
isolated	GeneRIF Biological Term Annotations	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-3915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62208
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.05797
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Galactosemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.903
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81406
Farber lipogranulomatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
Anterior chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1946
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29309
Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
Stoma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.078
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28478
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.09
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4978
BRD-K96652989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33898
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03471
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44917
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16868
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4472
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869469
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00028
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.57988
BRD-K88385836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03035
Bundle sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.934
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cataract 31 multiple types	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41441
SAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.113
OVTOKO	DepMap CRISPR Gene Dependency	1.0	2.5926
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.500398
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57434
Glycolate oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53632480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82092
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62659
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12693
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.103359
nc95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
CYB5RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39249
organelle organization	GO Biological Process Annotations 2015	1.0	null
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10884
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.237
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EMC-BAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23298
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3445_OE_Sca17_SRP248035	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.97088
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1907
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
epithelial cell development	GO Biological Process Annotations 2015	1.0	null
bephenium hydroxynaphthoate-5263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.578816
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30196
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0707
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EB2	CCLE Cell Line Gene Expression Profiles	1.0	1.41118
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
Neurofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.462
Fbxl10_OE_GDS4788_327_mouse_MEF fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44579
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941846
EB-3	GDSC Cell Line Gene Expression Profiles	1.0	1.85063
carbamoyl-phosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.528162
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13482
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45212
Perturb_16097_KO_Eed_SRP125082	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.84757
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.944498
Mitochondrial respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.823
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.977286
BRD-K82869745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43807
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.453259
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4109
BRD-K98195492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60147
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.90982
BRD-K12089436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49415
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.888579
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.829353
PAX3_01_359	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.85293
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Dxr protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.966
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1038
RFXAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47476
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.977332
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98105
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53464
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
Whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.547
Leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.278
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.51957
BRG1_DEPLETION_GDS2156_720_mouse_Embryos (maternally depleted)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72652
Phakinin	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02149
phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413532
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.15206
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24246
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.851149
Charcot-Marie-Tooth disease type 4F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
PACSIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76624
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.51263
Gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.11
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962074
SPI1-22096565-GC-B-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Vegetative stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4267
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48473
FOXM1-26456572-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26187
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.515
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.7752
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.94366
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
BRD-K42679315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07885
Orthogonal array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.529
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10599
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
flag leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.982386
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.79
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.44914
BRD-K23496480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02775
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
UCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92284
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00824
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64534
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18849
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05985
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Charcot-Marie-Tooth disease axonal type 2CC	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49992
ZNF423	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02657
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39521
Inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.381
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Human - Fetal Development - L1 - Lens fibre cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.713
NCIH520	DepMap CRISPR Gene Dependency	1.0	2.32734
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43944
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1242
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.211007
Progressive Cataract	DisGeNET Gene-Disease Associations	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15697
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW982	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58443
BRD-K55393423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14038
GSE146074_9_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.363185
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11811
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039297
RAJI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
photosystem i	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.85045
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
increased corneal light-scattering	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.66992
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86899
BRD-K22670776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25954
BRD-K82314391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10181
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K08389897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34548
intermediate filament	GO Cellular Component Annotations 2025	1.0	null
BRD-K59587063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65068
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.47
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5244
CRCGN017_MCF10A.WT.HP_24H:K16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24695
importance	GeneRIF Biological Term Annotations	1.0	null
Lung Diseases	CTD Gene-Disease Associations	1.0	1.01286
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92193
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95467
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48736
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
KYSE270	DepMap CRISPR Gene Dependency	1.0	3.26545
Internode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
Tendril	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10679
No annotation - 1	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
TM4SF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13933
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
transferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.056106
PNKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53877
Perturb_1763_KD_Tcf1_SRP311399	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15896
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40596
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.84958
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15622
PSI associated light-harvesting complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.139
CI1	CCLE Cell Line Gene Expression Profiles	1.0	1.7231
Leukocoria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12169
OCI-AML3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.077
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74728
PCDHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17975
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02545
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17511
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950418
BRD-K93176491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41357
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K77290793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09726
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37162
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SG-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8555
Leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876959
BRD-K51600962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07253
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24273
more	GeneRIF Biological Term Annotations	1.0	null
CLPP_KO_GDS4791_104_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.182775
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71187
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU685	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11955
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3937
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02556
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32381
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11927
C1QBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92318
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90498
H3K9me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30043
TE4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25697
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88457
Perturb_4529_KD_Chaf1b_SRP060878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.04966
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.367
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96323
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29675
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47125
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0994
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043861
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Glutamate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.228