association dataset threshold value standardized value Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49663 Mus musculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76173 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.37624 external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1524 16484322-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08309 superficial stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36831 GTEX-S4P3-0426-SM-4AD56 GTEx Tissue Sample Gene Expression Profiles 1.0 0.847638 MCF7_Nintedanib_1µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0110058 breast cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.092951 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6782 TAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04576 COCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98995 forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055442 negative regulation of cellular process GO Biological Process Annotations 2015 1.0 null Integument TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 OB inner plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35135 EGR1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.870594 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPTSSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98175 GTEX-TSE9-0126-SM-3DB83 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34941 abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.120936 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null EOMES ChEA Transcription Factor Targets 1.0 null ACYP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19484 GTEX-S3XE-1726-SM-3K2AM GTEx Tissue Sample Gene Expression Profiles 1.0 1.29193 GTEX-PWO3-1526-SM-48TCM GTEx Tissue Sample Gene Expression Profiles 1.0 1.6241 GTEX-OIZH-0126-SM-2HMIS GTEx Tissue Sample Gene Expression Profiles 1.0 1.64646 GTEX-XBED-1026-SM-48TCB GTEx Tissue Sample Gene Expression Profiles 1.0 0.877001 Perturb_17169_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-WZTO-0011-R10B-SM-4E3KB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08138 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07735 GTEX-R55F-0126-SM-48FCK GTEx Tissue Sample Gene Expression Profiles 1.0 0.921884 GTEX-WHWD-1826-SM-3LK6I GTEx Tissue Sample Gene Expression Profiles 1.0 1.20859 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C0-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S3XE-0926-SM-4AD4S GTEx Tissue Sample Gene Expression Profiles 1.0 0.835083 PECAPJ49 DepMap CRISPR Gene Dependency 1.0 2.80142 superficial stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69568 GSE164529_0_v_1_tamoxifen_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_699_KO_INTS6_SRP299234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01865 Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.66105 EGR1 ENCODE Transcription Factor Targets 1.0 null GTEX-RN64-0126-SM-2TC68 GTEx Tissue Sample Gene Expression Profiles 1.0 0.938482 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-0526-SM-3LK7W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60186 lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -1.32825 ZBTB32 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0896 Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.192 I-cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.878 intermediate stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1158 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MPHOSPH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11138 GTEX-T6MN-0226-SM-32PMD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15121 Perturb_2630_OE_ROR2_SRP293436 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.97468 HEATR5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19151 GTEX-UPIC-1426-SM-4IHLQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.12496 GTEX-R3RS-1326-SM-48FE7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38517 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.381003 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908516 Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 PPP2CB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3936 GSE175787_11_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2G_02_130 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59593 hsa-miR-3064-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 VANGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50475 SNAI2_01_225 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 9.14561 Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02623 NCIH810 CCLE Cell Line Gene CNV Profiles 1.0 1.52668 biological_process GO Biological Process Annotations 2015 1.0 null PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR Rummagene Transcription Factor Associations 2026 1.0 null PXDN Pathway Commons Protein-Protein Interactions 1.0 null UM-UC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.954901 PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null HCC1187 CCLE Cell Line Gene CNV Profiles 1.0 1.61162 Integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15127 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.047 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33461 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.04985 NCI-H2110 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 spleen HPA Tissue Protein Expression Profiles -1.0 -2.36012 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0837 GTEX-WXYG-2326-SM-4E3I6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15488 PHGDH_KO_GDS2874_125_mouse_embryonic head tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 4.04048 Lung adenocarcinoma_LUAD_TCGA-78-7167-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUDHL10 DepMap CRISPR Gene Dependency 1.0 2.13229 GTEX-WOFL-0126-SM-3MJG2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.865193 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 GTEX-UPIC-1026-SM-4IHLT GTEx Tissue Sample Gene Expression Profiles 1.0 1.0403 GTEX-POYW-0008-SM-48TE4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.90162 hsa-miR-139-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.41234 GTEX-TML8-1926-SM-32QOS GTEx Tissue Sample Gene Expression Profiles 1.0 1.46487 EEF1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20773 bnip2 GeneRIF Biological Term Annotations 1.0 null GTEX-PWCY-0726-SM-48TCS GTEx Tissue Sample Gene Expression Profiles 1.0 1.16557 amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.979725 MIF Pathway Commons Protein-Protein Interactions 1.0 null FGFR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0599 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.77154 negative regulation of cell population proliferation GO Biological Process Annotations 2025 1.0 null SW 527 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911645 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UPIC-1626-SM-4IHKT GTEx Tissue Sample Gene Expression Profiles 1.0 1.50922 medial geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53846 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7009 GSE133329_0_v_3_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null NB1643 DepMap CRISPR Gene Dependency 1.0 2.26084 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1226 SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5647 CAMA1 CCLE Cell Line Gene Expression Profiles 1.0 1.49592 Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34021 TRIM28_knockout_303_GSE32224 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.41594 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.857863 KBTBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92002 Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07718 Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23746 HCT-116 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.69 NPAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47334 CAOV-4 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 GSE149264,GSE149267_2_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.98951 PMC6855629-pone.0225186.s005.xlsx-Sheet1-DEGs_upregulated_in_the_low_MEIS1_content_thalamus_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.189 GTEX-T5JW-0726-SM-4DM6D GTEx Tissue Sample Gene Expression Profiles 1.0 0.956991 GTEX-S32W-0926-SM-4AD5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.899925 USE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66545 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.39117 Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54451 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08309 Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4EO-0326-SM-3P5YO GTEx Tissue Sample Gene Expression Profiles 1.0 1.02188 olfactory part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89535 T3M10 CCLE Cell Line Gene CNV Profiles -1.0 -1.855 GSE139966_1_v_0_figla_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-R3RS-0126-SM-3GIJL GTEx Tissue Sample Gene Expression Profiles 1.0 1.4712 Midbrain, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19026 PWWP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20517 superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.03692 GSE173201_0_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null bonemarrow_6c HPA Tissue Sample Gene Expression Profiles -1.0 -0.854275 GTEX-RWS6-0826-SM-47JXF GTEx Tissue Sample Gene Expression Profiles 1.0 1.0526 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.856903 H3K36me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.098 KARPAS299 CCLE Cell Line Gene CNV Profiles 1.0 1.82044 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.899053 GSE217405_3_v_2_osimertinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null LRRC8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35802 Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.188 NCI-H810 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 GTEX-XBEW-1326-SM-4AT63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26339 GTEX-WXYG-2026-SM-4E3IY GTEx Tissue Sample Gene Expression Profiles 1.0 1.23016 PDSS2_KO_GDS3454_120_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null membrane LOCATE Predicted Protein Localization Annotations 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null GTEX-T8EM-0526-SM-4DM64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14224 GTEX-Q2AG-0126-SM-33HBV GTEx Tissue Sample Gene Expression Profiles 1.0 1.31506 NT5DC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2568 ZNF460 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 103.579 GTEX-OXRN-0126-SM-48TDM GTEx Tissue Sample Gene Expression Profiles 1.0 1.31711 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63763 GTEX-PWN1-1826-SM-2S1PE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09053 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.3509 CLN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.62383 GTEX-WQUQ-0426-SM-3MJFU GTEx Tissue Sample Gene Expression Profiles 1.0 1.55099 UBL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07267 GTEX-WY7C-2326-SM-3NB2U GTEx Tissue Sample Gene Expression Profiles 1.0 1.07004 Acute Myeloid Leukemia_LAML_TCGA-AB-2886-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VMRCLCD DepMap CRISPR Gene Dependency 1.0 3.42452 Cerebral cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54604 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.4097 P63-20808887-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_5_EBF1 Rummagene Transcription Factor Associations 2026 1.0 null telencephalic vesicle Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51176 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EIF4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98056 RRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23826 blood vessel GTEx Tissue Gene Expression Profiles -1.0 -1.05767 POLR3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10486 Lung adenocarcinoma_LUAD_TCGA-86-8281-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PLZ6-1426-SM-2S1OQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.43177 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.291787 GTEX-OHPL-3026-SM-3MJGS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13292 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral part of m1A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4137 RPL21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73186 adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.309335 Lung squamous cell carcinoma_LUSC_TCGA-77-A5G3-01A-31R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF1A_01_02 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59918 ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.538209 KDR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75817 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDC20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15163 GSE138789_0_v_1_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.15322 JHUEM1 DepMap CRISPR Gene Dependency 1.0 2.01358 Lung adenocarcinoma_LUAD_TCGA-50-6593-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRC_DEPLETION_GDS3532_96_human_U2OS cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8260-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE211177,GSE211178_4_v_1_ets1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE152441,GSE152442_6_v_5_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null MCF7_Mocetinostat_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.00804298 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.09141 central part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55504 PAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39759 Attention deficit hyperactivity disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.638 GTEX-R55C-1826-SM-3GADI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.54008 UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.25921 GTEX-RNOR-0126-SM-2TF57 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07729 H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LNZTA3WT4 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3 Rummagene Transcription Factor Associations 2026 1.0 null Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.442 SNU840 DepMap CRISPR Gene Dependency 1.0 2.19445 GSE193351_4_v_0_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null Brain - Caudate (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 1.0 1.57695 GDAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57156 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42381 PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null ZR7530 CCLE Cell Line Gene Expression Profiles 1.0 1.72338 GSE193351_1_v_2_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00877 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IZ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.79707 Prostate adenocarcinoma_PRAD_TCGA-G9-6353-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nci-h226 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.20387 churg-strauss syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.790492 Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11764 CDK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39315 GTEX-S33H-0826-SM-4AD5Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.08894 primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.948709 RPL37A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13134 KLF13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1705 SP in perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958595 GSE62843,GSE64371_2_v_0_furan_mouse RummaGEO Drug Perturbation Signatures 1.0 null Glutaminase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.855 MKN74 CCLE Cell Line Gene Expression Profiles 1.0 1.35436 r10 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37541 496100502_TCx_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.4945 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.846573 POLE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31819 GTEX-T5JW-1626-SM-3GADZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.82144 primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26702 NKM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZBTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74114 RERFLCKJ CCLE Cell Line Gene Expression Profiles 1.0 1.76481 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.24445 Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.92793 GTEX-QLQ7-1926-SM-2S1R6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850208 POLR2A ENCODE Transcription Factor Targets 1.0 null amygdaloid complex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.923381 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null ATP6V1E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07875 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GTEX-UPJH-0226-SM-3GADV GTEx Tissue Sample Gene Expression Profiles 1.0 1.31516 Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86407 DDI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04298 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.07811 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.09198 TPCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84246 DBH_KO_GDS4324_362_mouse_Embryonic heart E10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0224 RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.850925 NCC010 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T6MN-0126-SM-32PLP GTEx Tissue Sample Gene Expression Profiles 1.0 1.75492 GSE242290_1_v_2_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null cytosol COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-OHPL-1326-SM-3MJGG GTEx Tissue Sample Gene Expression Profiles -1.0 -2.17788 GTEX-X4XX-0126-SM-3NMC2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14518 GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12573 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.68141 GSE232631_0_v_2_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3934 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 496100559_FWM_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06733 20220088-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18846 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null fat_e HPA Tissue Sample Gene Expression Profiles -1.0 -0.912391 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12361 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8793 cytosol COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66599 Main olfactory bulb, granule layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05316 superficial stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54009 dorsolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.880673 intracellular organelle GO Cellular Component Annotations 2015 1.0 null CEBPB-21427703-3T3-L1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-PLZ6-1626-SM-3NB23 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50277 primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28979 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-RM2N-1426-SM-2TF4H GTEx Tissue Sample Gene Expression Profiles 1.0 1.2352 GPKOW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03336 Agranular insular area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07863 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF507 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.59557 GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.938687 GTEX-WRHU-0726-SM-3MJFL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972794 GTEX-RWS6-2026-SM-2XCB5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40367 Male reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.042 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 3.24385 hsa-miR-3160-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 PBX1 ChEA Transcription Factor Targets 1.0 null mantle zone of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03134 GTEX-SNMC-0526-SM-4DM69 GTEx Tissue Sample Gene Expression Profiles 1.0 0.921508 hsa-miR-4699-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.6151 GSE148066,GSE157787_8_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7031 Prostate adenocarcinoma_PRAD_TCGA-EJ-7321-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Storage vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.534 SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.828688 697 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.57 Photoreceptor connecting cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.789 Cortical plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57848 intracellular part GO Cellular Component Annotations 2015 1.0 null H3K4me1_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.156 GSE158969_1_v_2_trastuzumab_human RummaGEO Drug Perturbation Signatures 1.0 null GSE121824,GSE121826_0_v_2_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null Anteromedial visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03263 respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054864 GTEX-R55E-0011-R9A-SM-2TC6C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.80919 CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PDZD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18806 GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.849891 Lung squamous cell carcinoma_LUSC_TCGA-58-8392-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4QT-0126-SM-2I3FL GTEx Tissue Sample Gene Expression Profiles 1.0 1.892 GTEX-WHSE-0011-R4A-SM-3P5ZN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.988034 TMEM200A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.52091 breast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.287447 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.980032 IL11RA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.52129 GTEX-U412-0426-SM-3DB9O GTEx Tissue Sample Gene Expression Profiles 1.0 1.42025 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.892673 m1Lim (VL) part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52013 496100515_HIP_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.08023 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.02011 ventrolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.43095 Colon - Transverse GTEx Tissue Gene Expression Profiles 2023 1.0 3.19175 r8 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1526 skmel31 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.913 GTEX-P4PQ-0226-SM-2S1NK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.828451 Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11916 BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.27229 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.653 GSE153189_1_v_3_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE220914_1_v_0_zdhhc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81671 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04688 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42898 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17903 GTEX-S7SE-0011-R7A-SM-2XCDI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.964476 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null proliferation GeneRIF Biological Term Annotations 1.0 null NTHL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00177 trigeminal nerve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.9094 H3K36me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE161864,GSE161866_0_v_2_ror2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XUZC-0426-SM-4BOPE GTEx Tissue Sample Gene Expression Profiles 1.0 0.829693 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.77862 H3K79me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null disease of metabolism GWASdb SNP-Disease Associations 1.0 0.083057 GTEX-WEY5-2126-SM-3GILK GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 GSE227698_5_v_1_g0s2_human RummaGEO Gene Perturbation Signatures 1.0 null arrest GeneRIF Biological Term Annotations 1.0 null intracellular COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13275 Bcl2-/adenovirus E1B 19kDa-interacting protein 2 InterPro Predicted Protein Domain Annotations 1.0 null MFAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41831 Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.0024 Perturb_13912_KD_TARDBP_SRP169127 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.13391 tick-borne encephalitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.229 GTEX-PLZ6-0526-SM-3P61C GTEx Tissue Sample Gene Expression Profiles 1.0 1.12659 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.9497 PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_1_PRDM6 Rummagene Transcription Factor Associations 2026 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null NCI-H1395 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 GTEX-S3XE-1826-SM-3K2B4 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.13326 GTEX-WEY5-2326-SM-3GIKK GTEx Tissue Sample Gene Expression Profiles 1.0 0.891059 GSE239844_8_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XGQ4-2226-SM-4AT4Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18281 UBB_KO_GDS3906_491_mouse_Testis - 7 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0224 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null trigeminal neuralgia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.91033 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908516 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5O9-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43177 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 Perturb_13907_KD_UBE3A_SRP124518 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.4477 GTEX-UJHI-0826-SM-4IHLM GTEx Tissue Sample Gene Expression Profiles 1.0 0.958595 GSE175787_4_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 cellular process GO Biological Process Annotations 2015 1.0 null GTEX-XXEK-1626-SM-4BRUZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.995873 GTEX-OXRP-0126-SM-3NB32 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879738 TMEM259 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5877 GTEX-WYJK-0526-SM-3NM8Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.0604 GSE181959_1_v_0_dextran_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-TSE9-1226-SM-4DXTM GTEx Tissue Sample Gene Expression Profiles 1.0 0.835617 skin GTEx Tissue Gene Expression Profiles 1.0 1.29233 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null leukocyte disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.065274 CTU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16424 Nucleus of the lateral olfactory tract, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13701 RNF213 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95653 CL-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.49493 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr1_151037158_T_C_b38 GTEx eQTL 2025 1.0 4.42231 GTEX-T5JC-1726-SM-4DM6U GTEx Tissue Sample Gene Expression Profiles 1.0 1.31067 UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.933292 496100412_FWM_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.98897 CORL95 CCLE Cell Line Gene Expression Profiles -1.0 -2.58787 SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.82776 RECQL5 Pathway Commons Protein-Protein Interactions 1.0 null MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.967913 NB1 CCLE Cell Line Gene CNV Profiles 1.0 1.36273 GTEX-WFJO-0726-SM-4LVM8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.987593 GSE253041_1_v_0_ramp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null EPOP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9123 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87624 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null 501A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.41499 ELF1 ENCODE Transcription Factor Targets 1.0 null SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19404 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83186 ABC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18753 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.17043 PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE Rummagene Transcription Factor Associations 2026 1.0 null NSA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25395 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973604 COA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10489 ZNF391 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38057 GTEX-XPT6-2226-SM-4B66R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844743 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6345883-41598_2018_37397_MOESM10_ESM.xlsx-AR_D0_VS_D7_WO_B29__TRANS-Gene_Name_AR Rummagene Transcription Factor Associations 2026 1.0 null SPHK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77761 H357 DepMap CRISPR Gene Dependency 1.0 3.25272 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.839765 PPM1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22435 negative regulation of cell population proliferation GO Biological Process Annotations 2023 1.0 null lung cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060574 NSDHL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02573 TUBG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39878 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.844377 AP5S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12486 EIF4ENIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32987 EGR1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76506 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68927 IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null esophagus_5b HPA Tissue Sample Gene Expression Profiles 1.0 1.27073 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18168 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.20315 GSE147366_1_v_4_med13_human RummaGEO Gene Perturbation Signatures -1.0 null Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2 Rummagene Transcription Factor Associations 2026 1.0 null SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.855103 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE76425_0_v_10_lenalidomide_human RummaGEO Drug Perturbation Signatures 1.0 null mRNA_T_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null MDAMB415 CCLE Cell Line Gene Expression Profiles 1.0 1.38195 H3K36me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 GTEX-XK95-0226-SM-4AT58 GTEx Tissue Sample Gene Expression Profiles 1.0 0.831912 regulation of cell proliferation GO Biological Process Annotations 2015 1.0 null GTEX-S7SF-0926-SM-4AD4M GTEx Tissue Sample Gene Expression Profiles 1.0 1.04277 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8428 mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19563 CAKI-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.36602 cognitive impairment GWASdb SNP-Phenotype Associations 1.0 0.663117 ventrolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14608 Lung adenocarcinoma_LUAD_TCGA-78-7156-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0615 bcl2adenovirus GeneRIF Biological Term Annotations 1.0 null YBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08519 DBNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35873 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79708 Tachycardia_Myocardial tissue_GSE7999 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.60116 IZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13978 r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09367 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.85994 APTX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01269 GTEX-QDT8-0011-R2A-SM-32PKQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.912743 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.838335 LONP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37868 primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29589 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0414 RNF115 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13062 Perturb_2585_OE_ROR2_SRP065310 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.27233 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 SCC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.91983 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.13379 U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.63716 GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.906907 Perturb_11684_KD_NCAPH2_SRP157799 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.86125 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4773 LC-1-SQ COSMIC Cell Line Gene Mutation Profiles 1.0 null CRLF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2192 LN443 CCLE Cell Line Gene CNV Profiles -1.0 -1.45402 Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE123638,GSE123639_0_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WL46-0011-R1A-SM-3LK6M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24721 Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15173_KO_PTPN14_SRP167101 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.50129 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 GTEX-X3Y1-2026-SM-3P5YM GTEx Tissue Sample Gene Expression Profiles 1.0 0.922021 AVPI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80393 regulate GeneRIF Biological Term Annotations 1.0 null p16ink4 GeneRIF Biological Term Annotations 1.0 null GTEX-QLQ7-1626-SM-2S1R8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08528 GSE111035,GSE111040_8_v_5_plag1_mouse RummaGEO Gene Perturbation Signatures -1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19891 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-0526-SM-4AD5N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.854018 GSE91015_0_v_1_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WHWD-2426-SM-3LK6S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24549 SSTR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.54769 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.83025 GTEX-WYJK-1426-SM-3NM8V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34697 smooth muscle HPA Tissue Gene Expression Profiles -1.0 -1.33619 GSE232631_5_v_1_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null LRRC75A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26387 TAGLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26497 mRNA_RXRA_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-S7SE-0011-R10A-SM-2XCDF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07389 MGAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26987 carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.482817 GTEX-WY7C-2526-SM-3NB2N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39205 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045969 Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7SF-1426-SM-4AT5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.29902 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null apoptotic process GO Biological Process Annotations 2015 1.0 null NCIH3122 DepMap CRISPR Gene Dependency 1.0 3.2324 496100365_HIP_probable Alzheimer's disease_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.8755 GTEX-S32W-2126-SM-2XCB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07366 Organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 ventral linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28868 anterior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.845181 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14793 GTEX-SNOS-0926-SM-4DM7A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13259 liver cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.08423 496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.72901 KARPAS-299 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 Anteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77898 GTEX-WY7C-0526-SM-3NB3D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.94275 Perturb_2792_KO_LATS1/LATS2_SRP331116 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_4789_KD_Firre_ERP009127 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.84896 NUBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81381 GTEX-QDVJ-0826-SM-48U1S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32485 ANKS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9295 GPN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27219 adrenal gland GTEx Tissue Gene Expression Profiles -1.0 -0.84451 GSE205556_1_v_0_bexarotene_human RummaGEO Drug Perturbation Signatures 1.0 null Ventral posteromedial nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02312 Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_ZFP42_19618472 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.88148 CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3173-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 DESI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10545 NHERF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20713 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.928535 496100499_PCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.16242 SIRT4_KO_GDS4823_22_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.945974 ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00993 SP1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126777_3_v_1_otub1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.0622 GTEX-X4XY-0526-SM-46MW1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.99981 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZM-01A-12R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30049 H2AB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06719 LUDLU1 DepMap CRISPR Gene Dependency 1.0 2.29845 PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3 Rummagene Transcription Factor Associations 2026 1.0 null supramarginal gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.827884 GTEX-Q734-1926-SM-2I5EV GTEx Tissue Sample Gene Expression Profiles 1.0 0.931275 NCI-H1623 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 GSE149264,GSE149267_9_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null THRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83834 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.567 GSE150895,GSE150896_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null protein binding GO Molecular Function Annotations 2015 1.0 null EIF3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03152 GTEX-RVPV-0526-SM-47JYL GTEx Tissue Sample Gene Expression Profiles 1.0 0.966764 DU4475 DepMap CRISPR Gene Dependency 1.0 2.62506 r2 part of nucleus subcoeruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12343 negative regulation of cellular process GO Biological Process Annotations 2023 1.0 null POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A427 DepMap CRISPR Gene Dependency 1.0 3.08129 Lung squamous cell carcinoma_LUSC_TCGA-77-7335-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 soft tissue HPA Tissue Protein Expression Profiles -1.0 -0.894951 AMO-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.954901 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.68906 GTEX-PWN1-2526-SM-48TDS GTEx Tissue Sample Gene Expression Profiles 1.0 1.16124 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41881 WHSC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACHN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.17747 DCAF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53581 mRNA_EOMES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IK-01A-32R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRK-0226-SM-3NB2G GTEx Tissue Sample Gene Expression Profiles 1.0 1.0449 GTEX-REY6-1326-SM-48FDO GTEx Tissue Sample Gene Expression Profiles 1.0 1.06928 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FP-01A-21R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03643 prepontine hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17692 layer 1 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40118 regulation of cell population proliferation GO Biological Process Annotations 2025 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.985985 SLC7A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34528 U2SURP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77012 GATA6-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KMS11 CCLE Cell Line Gene CNV Profiles 1.0 1.43707 layer 2 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06479 201T COSMIC Cell Line Gene Mutation Profiles 1.0 null CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.96237 GSE227698_2_v_1_g0s2_human RummaGEO Gene Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.66999 DNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14029 ZKSCAN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7852 GSE145915_0_v_2_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S7SF-2226-SM-3K2BG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40632 Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RVPU-0008-SM-3NM8B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64485 ALS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42988 Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOL4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51257 Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59736 MYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8703 principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.97733 inner CP in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.93376 Intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1689 GTEX-OOBK-0625-SM-3LK5P GTEx Tissue Sample Gene Expression Profiles 1.0 1.06348 GSE230744,GSE237803_5_v_2_hira_human RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE157383_3_v_1_abemaciclib_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_17168_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-QESD-1426-SM-2S1R9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.974381 dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25452 GTEX-T5JC-0226-SM-32PMA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11746 m1 part of parabrachialis pigmentosus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00288 GTEX-UJMC-0008-SM-4IHKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.94724 mediodorsal nucleus of thalamus_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03056 VCY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34704 DK-MG COSMIC Cell Line Gene Mutation Profiles 1.0 null r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24449 substantia innominata/basal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1505 GTEX-NFK9-1126-SM-3LK78 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00632 PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8 Rummagene Transcription Factor Associations 2026 1.0 null POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4619 B-cell lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04 GTEX-XUJ4-1826-SM-4BOOU GTEx Tissue Sample Gene Expression Profiles 1.0 1.10739 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.931566 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Osteoporosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 GTEX-VUSG-2526-SM-4KL1V GTEx Tissue Sample Gene Expression Profiles 1.0 1.47197 breast adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.342971 EGR1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRAL-TRIO domain InterPro Predicted Protein Domain Annotations 1.0 null striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.09008 QSER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30799 GTEX-S7SE-0826-SM-4AT4D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.905792 dorsolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.32817 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.168 SNU489 CCLE Cell Line Gene Expression Profiles -1.0 -3.16846 cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 NCIH1869 CCLE Cell Line Gene Expression Profiles 1.0 1.94154 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T2IS-1026-SM-32QP1 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.11042 SNCA_KO_GDS4153_528_mouse_cerebellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-WZTO-0126-SM-3NM95 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00502 periventricular stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52177 GTEX-WRHK-1726-SM-3MJFK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42324 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null planum polare, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2841 Anus cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.278 BAX Pathway Commons Protein-Protein Interactions 1.0 null MYT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46931 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null musculoskeletal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.058741 GSE126777_0_v_1_otub1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RELB_RELB Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16001 SLC39A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03733 posteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.21291 HCC2157 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 scale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.78938 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043601 Type 2 diabetes GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.804576 GTEX-PWCY-2226-SM-2S1OP GTEx Tissue Sample Gene Expression Profiles -1.0 -2.05829 intracellular membrane-bounded organelle GO Cellular Component Annotations 2025 1.0 null Anterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25751 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16639 PHC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94116 RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9405 GSE198165,GSE198166_0_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.43324 GSE198165,GSE198166_5_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61107 GSE74528_0_v_1_trex2_mouse RummaGEO Gene Perturbation Signatures 1.0 null CNOT6L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26324 NCI-H1793 COSMIC Cell Line Gene Mutation Profiles 1.0 null L3HYPDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31547 Perturb_17189_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.044394 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null WHRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62109 splicing GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6336-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7534 ADGRE5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74709 DOR 13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15705 Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT144SKINFV1 DepMap CRISPR Gene Dependency 1.0 2.53523 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4655 PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Unnamed_1_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null JEG3 DepMap CRISPR Gene Dependency 1.0 2.6425 CRTC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22544 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59126 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null discussed GeneRIF Biological Term Annotations 1.0 null T47D CCLE Cell Line Gene Expression Profiles 1.0 2.6549 MCAD_KO_GDS4546_423_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_17179_OE_ESR1_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-PVOW-0011-R3A-SM-32PKX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.93129 JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null ventral lateral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.964528 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.211 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.56746 GTEX-SNOS-1726-SM-32PLN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.97956 LCLC-103H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.23644 GSE242290_3_v_2_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.08295 Brain - Hippocampus GTEx Tissue Gene Expression Profiles 2023 1.0 4.21195 globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30633 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Verrucous papilloma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.513 ZC3H14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1784 Perturb_2631_OE|KD_ROR2|WNT11_SRP293436 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE122711_2_v_3_mpc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE102870_11_v_9_nr1h4_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-1252 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GTEX-PWN1-0126-SM-2I3FK GTEx Tissue Sample Gene Expression Profiles 1.0 1.54458 GTEX-PW2O-1926-SM-2S1OB GTEx Tissue Sample Gene Expression Profiles -1.0 -2.23903 NCIH1437 CCLE Cell Line Gene CNV Profiles 1.0 2.293 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.883527 PMC9950457-mmc3.xlsx-GRHL2_overexpression_UP-gene_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null Primary somatosensory area, lower limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16384 KPNSI9S CCLE Cell Line Gene Expression Profiles -1.0 -1.51903 SF539 DepMap CRISPR Gene Dependency 1.0 2.20977 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null periventricular stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00407 Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12379 GNPTG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.34646 Skin cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 MRK-NU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2AphosphoS2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null variants GeneRIF Biological Term Annotations 1.0 null STRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3869 17660535-TableS4c GeneSigDB Published Gene Signatures 1.0 null medial (magnocellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01939 USF2_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-DLX5_DLX5 Rummagene Transcription Factor Associations 2026 1.0 null Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TGFBR2_knockout_296_GSE22989 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.82628 SLC23A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18594 Main olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3251 Cell type cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973604 SP1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.572 cortex of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00189 GTEX-U8XE-1026-SM-4E3HM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.992081 amygdaloid complex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.894214 primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.51226 GTEX-N7MT-0326-SM-48TDP GTEx Tissue Sample Gene Expression Profiles 1.0 1.08212 HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22932 RAB38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.98293 496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00286 regulation of growth rate GO Biological Process Annotations 2025 1.0 null GSE178292_0_v_3_melphalan_human RummaGEO Drug Perturbation Signatures 1.0 null ABCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40447 NHEK Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.44915 GTEX-Q2AH-1726-SM-3NB2B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31942 HCC1419 CCLE Cell Line Gene Expression Profiles 1.0 1.43163 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6MB-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFG7-1626-SM-4LVMF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.880528 gallbladder HPA Tissue Protein Expression Profiles 1.0 3.27095 GSTZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22583 Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.873869 posterior triangular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4339 GTEX-S4Z8-1726-SM-3K2AX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12425 GTEX-U3ZM-1526-SM-3DB9D GTEx Tissue Sample Gene Expression Profiles 1.0 1.37736 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HI-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.57595 GTEX-XUW1-0926-SM-4BONX GTEx Tissue Sample Gene Expression Profiles 1.0 1.65716 GCIY COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TKQ1-0326-SM-4DXSM GTEx Tissue Sample Gene Expression Profiles 1.0 1.0151 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.849523 TRIM45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33994 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76593 Lung squamous cell carcinoma_LUSC_TCGA-85-8071-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTHFSD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52051 GSE138818_1_v_3_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF770 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.1911 H3K27ac_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFKB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05544 TP63 ChEA Transcription Factor Targets 1.0 null lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.15132 PMC11952327-media-1.pdf-3-INSM2_INSM2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null KYSE30 CCLE Cell Line Gene Expression Profiles 1.0 2.13763 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.0254 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.53226 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-7498-01A-12R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 CASKIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01595 r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01343 Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3314 mantle zone of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4137 GSE154074_5_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null MDAMB134VI CCLE Cell Line Gene Expression Profiles 1.0 1.43294 HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02135 Prostate adenocarcinoma_PRAD_TCGA-HC-8259-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_MSC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-RU72-0926-SM-2TF6B GTEx Tissue Sample Gene Expression Profiles 1.0 0.876663 GTEX-OHPN-0011-R4A-SM-2I5FD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.853271 PRRC2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60985 changes GeneRIF Biological Term Annotations 1.0 null JURLMK1 DepMap CRISPR Gene Dependency 1.0 3.26837 Perturb_17187_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-OIZI-1126-SM-3NB1F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86616 Main olfactory bulb, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56444 Cerebrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43177 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911645 Perturb_17172_OE_ESR1_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057792 Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE239844_6_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null FOXJ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46396 JAK1_druginhibition_165_GSE38335 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.62875 GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.139341 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WH7G-0326-SM-3NMBH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27539 GTEX-QMRM-0626-SM-447BQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.922215 HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.626373 GTEX-WYBS-0426-SM-3NM9M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935612 posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01032 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.846256 GSE186633_2_v_0_chd1_human RummaGEO Gene Perturbation Signatures 1.0 null Protein storage vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.738 GTEX-WH7G-2326-SM-3NMBC GTEx Tissue Sample Gene Expression Profiles 1.0 1.07095 NCI-H82 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.838004 neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.088435 GSE86507,GSE86509_3_v_2_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04863 Perturb_12038_KO_Trps1_SRP201986 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.09811 MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1356 NKX3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03922 oval paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06973 striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.32817 GTEX-OHPM-0126-SM-2YUN9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.29712 death GeneRIF Biological Term Annotations 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null LYRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.59958 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7514 primary auditory cortex (core)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4763 TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2883 mif GeneRIF Biological Term Annotations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF4G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13919 GTEX-XUW1-0426-SM-4BOOT GTEx Tissue Sample Gene Expression Profiles 1.0 1.29525 Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.044991 SNU-719 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.842872 layer 2 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00407 17975224-TableS6 GeneSigDB Published Gene Signatures 1.0 null bj HPA Cell Line Gene Expression Profiles -1.0 -1.35296 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22594 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.37624 GTEX-SN8G-0126-SM-32PLI GTEx Tissue Sample Gene Expression Profiles 1.0 1.18931 496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.26908 confers GeneRIF Biological Term Annotations 1.0 null Medial geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44322 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.08861 SIRT4_KO_GSE56321_391_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH23 DepMap CRISPR Gene Dependency 1.0 2.98622 GTEX-QDVJ-1726-SM-2I5FX GTEx Tissue Sample Gene Expression Profiles 1.0 1.13119 NB13 DepMap CRISPR Gene Dependency 1.0 4.25468 GTEX-WYBS-0626-SM-3NMAS GTEx Tissue Sample Gene Expression Profiles 1.0 0.867546 Prostate cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.042 TMEM185A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39403 NCI-H345 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 GTEX-RTLS-1126-SM-46MUQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.937338 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.025751 GTEX-RU72-0226-SM-46MUD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03802 20174566-TableS1 GeneSigDB Published Gene Signatures 1.0 null GSE210885_5_v_6_klf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.856526 PMC4046566__F2 PFOCR Pathway Figure Associations 2024 1.0 null MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6385 internal female genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-O5YV-1026-SM-3LK72 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3673 Lung adenocarcinoma_LUAD_TCGA-78-7633-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EH-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.839735 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9469 GTEX-OHPL-0426-SM-3TW8X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845408 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.453 VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30669 Thymus Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.89274 hsa-miR-3194-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.908166 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8993 DLG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48468 GTEX-TMMY-0226-SM-33HBA GTEx Tissue Sample Gene Expression Profiles 1.0 1.63415 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.957125 death GO Biological Process Annotations 2015 1.0 null HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.841691 FKBP8 Pathway Commons Protein-Protein Interactions 1.0 null rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05742 Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JAK2_druginhibition_167_GSE38335 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.62875 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2933 GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.903901 Prostate adenocarcinoma_PRAD_TCGA-EJ-7793-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.02369 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null mantle zone of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40414 Connective tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 GTEX-U8XE-0626-SM-3DB8U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6553 dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18766 Photoreceptor distal connecting cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.816 Lung Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.36793 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.949676 hepatoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.395709 PI4KB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24686 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0819 Body Mass Index DisGeNET Gene-Phenotype Associations 1.0 null RI1 DepMap CRISPR Gene Dependency 1.0 2.52246 cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060898 Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 19036130-TableS1a GeneSigDB Published Gene Signatures 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19404 PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null Placenta TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.870421 GTEX-XOTO-0726-SM-4B659 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23385 DRAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69006 GTEX-QDVN-2026-SM-3GAEP GTEx Tissue Sample Gene Expression Profiles 1.0 0.898063 GTEX-T5JC-0011-R8A-SM-32PLM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.839595 Gastric Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.30258 GSE190864,GSE190907_1_v_0_cacybp_human RummaGEO Gene Perturbation Signatures -1.0 null Brain - Cerebellar Hemisphere GTEx Tissue Gene Expression Profiles 2023 1.0 4.32581 hsa-miR-3945 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 SNU685 CCLE Cell Line Gene Expression Profiles -1.0 -1.6203 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null GSE171175,GSE171181_1_v_2_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null CHST4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31429 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.962601 neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.671925 GTEX-QEG4-0226-SM-2S1PY GTEx Tissue Sample Gene Expression Profiles 1.0 0.954052 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.939711 GTEX-XQ3S-0126-SM-4BOO9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6146 Primary somatosensory area, barrel field, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3446 GTEX-PWN1-0226-SM-2S1OZ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 NCI-H1876 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 RMUGS CCLE Cell Line Gene Expression Profiles 1.0 1.61675 GTEX-U3ZH-1726-SM-3DB79 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38506 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE214685_0_v_1_nsun2_human RummaGEO Gene Perturbation Signatures -1.0 null H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59914 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.05939 Cayman type cerebellar ataxia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.347 hsa-miR-4277 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GTEX-WRHK-0826-SM-3MJFG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68858 posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.91745 SF126 CCLE Cell Line Gene Expression Profiles -1.0 -1.71255 cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059183 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.46838 HRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3359 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MP-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE173810_4_v_6_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null TNPO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04907 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50G-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49446 hsa-miR-1268 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Body mass index GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.839794 GTEX-X88G-0126-SM-47JZ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.48539 BNIP2 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-2A-A8VL-01A-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFON-2526-SM-3LK7P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.975746 LAMA84 CCLE Cell Line Gene Expression Profiles -1.0 -1.62424 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RNOR-1226-SM-48FDQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.903437 cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.98272 Perturb_17193_OE_ESR1_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 lymphotoxin GeneRIF Biological Term Annotations 1.0 null GTEX-QV31-0326-SM-447BM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75446 GSE164529_0_v_2_tamoxifen_human RummaGEO Drug Perturbation Signatures -1.0 null Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95107 GTEX-O5YW-1826-SM-2YUN2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850632 significance GeneRIF Biological Term Annotations 1.0 null indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33046 GTEX-QVUS-0626-SM-447CC GTEx Tissue Sample Gene Expression Profiles 1.0 1.04122 GSE211215_1_v_0_pemetrexed_human RummaGEO Drug Perturbation Signatures 1.0 null Posterior parietal association areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75594 GSE148692,GSE148695_7_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null MED16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73102 GTEX-R55G-0426-SM-48FDH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825899 BHY CCLE Cell Line Gene CNV Profiles -1.0 -1.3633 layer 3 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03027 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCTD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08925 GSE106654_0_v_1_klf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PWCY-1926-SM-3NB25 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37647 Metencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 GSE227698_2_v_4_g0s2_human RummaGEO Gene Perturbation Signatures 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.33989 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.958835 PMC7318773__F3 PFOCR Pathway Figure Associations 2024 1.0 null Dorsomedial nucleus of the hypothalamus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1054 GTEX-VUSG-1226-SM-4KKZF GTEx Tissue Sample Gene Expression Profiles 1.0 1.18096 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.92694 u87 HPA Cell Line Gene Expression Profiles -1.0 -2.386 GSE203158_12_v_15_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23693 GSTM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70107 dorsolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.76746 homologue GeneRIF Biological Term Annotations 1.0 null DMS273 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.35112 H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ONS76 DepMap CRISPR Gene Dependency 1.0 2.37645 GSE96641_5_v_0_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.84251 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null intermediate-density lipoprotein particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.669 GTEX-XXEK-2226-SM-4BRUM GTEx Tissue Sample Gene Expression Profiles 1.0 1.04425 PRKCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17258 Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.8815 GSE74251_2_v_3_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.68354 GSE145215_0_v_3_krt13_mouse RummaGEO Gene Perturbation Signatures -1.0 null Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -4.07476 POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZI-1426-SM-3NB1T GTEx Tissue Sample Gene Expression Profiles 1.0 0.944544 preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.295 GTEX-UJHI-1526-SM-3DB99 GTEx Tissue Sample Gene Expression Profiles 1.0 1.87788 tonsil HPA Tissue Protein Expression Profiles -1.0 -1.0195 KANSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49971 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVJ-1126-SM-48U1U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39402 GTEX-T5JC-2526-SM-4DM6G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21964 NCIH1573 CCLE Cell Line Gene Expression Profiles 1.0 1.48024 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.844805 ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10112 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WM88 DepMap CRISPR Gene Dependency 1.0 2.61977 TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00758 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.10585 amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.835621 DDX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46548 Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFON-1926-SM-3LK7L GTEx Tissue Sample Gene Expression Profiles 1.0 0.9341 Posterior limiting nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07718 GTEX-WRHU-0826-SM-3MJFN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.91424 ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59072 UBE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99477 GTEX-X8HC-1526-SM-46MWD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08703 Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STARD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60742 OB outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73929 respiratory system disease GWASdb SNP-Disease Associations 1.0 0.167962 GTEX-WL46-0011-R3A-SM-3TW8E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844668 GTEX-WHSE-1126-SM-3NMBU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930981 inhibition GeneRIF Biological Term Annotations 1.0 null central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.99525 mRNA_MYBL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX Rummagene Transcription Factor Associations 2026 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15623 SLC8A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2664 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08816 HCC2218 CCLE Cell Line Gene CNV Profiles 1.0 1.56616 NCIH1876 CCLE Cell Line Gene CNV Profiles 1.0 1.56945 PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null il12 GeneRIF Biological Term Annotations 1.0 null cochlear nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39272 Bone resorption disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 Cervical epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.793 CLDN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37138 PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1 Rummagene Transcription Factor Associations 2026 1.0 null H4K20me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null USP54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18432 primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.998146 GTEX-XAJ8-0926-SM-47JXZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.977029 GTEX-RM2N-1826-SM-2TF5B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.871752 GSE132948,GSE132949_4_v_3_msi2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-T2IS-0826-SM-4DM6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.03188 Medial geniculate complex, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44905 leiomyosarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.51842 H3K36me3_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null trail GeneRIF Biological Term Annotations 1.0 null ERBB3_knockdown_65_GSE19921 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -3.1183 cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.4777 SNAPIN Pathway Commons Protein-Protein Interactions 1.0 null Ophthalmic nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.578 GTEX-WFG8-2326-SM-3GILF GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 CTNNBIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69543 GSE138818_1_v_0_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null YMB1 CCLE Cell Line Gene CNV Profiles 1.0 1.52285 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.63111 Suprageniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78464 PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_0_EBF1 Rummagene Transcription Factor Associations 2026 1.0 null SNX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30672 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39383 regulation of growth rate GO Biological Process Annotations 2023 1.0 null GTEX-WFG8-2226-SM-3GIL9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00331 anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.57766 JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.43772 KLF7_01_340 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.1243 GSE171177,GSE171181_1_v_0_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null cellular GeneRIF Biological Term Annotations 1.0 null laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00891 hsa-miR-4459 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GTEX-RWS6-0008-SM-47JYV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.939979 Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02986 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04193 Organism form TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 PMC4366019-pone.0116096.s005.xlsx-Primary_positives_NOT_retested-Primary_S6P_positives_NOT_selected_for_retesting_with_the_4_individual_RNAi_used_in_the_intial_screen_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XUZC-1726-SM-4BRWS GTEx Tissue Sample Gene Expression Profiles 1.0 2.11586 PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null KARPAS1718 DepMap CRISPR Gene Dependency 1.0 2.16918 negative regulation of biological process GO Biological Process Annotations 2015 1.0 null MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0155 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15838 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.77908 GTEX-WHPG-2626-SM-3NMBR GTEx Tissue Sample Gene Expression Profiles 1.0 1.65332 NCIH929 CCLE Cell Line Gene CNV Profiles 1.0 1.46381 GTEX-PLZ5-2026-SM-2S1O4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.50682 GTEX-S32W-2326-SM-2XCAW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845407 GTEX-W5WG-1126-SM-4LMK4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.995367 ZBTB49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58739 SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.975889 globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2485 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.64504 GTEX-XOTO-0226-SM-4B66H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64347 HEY DepMap CRISPR Gene Dependency 1.0 2.92432 Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09605 GTEX-T6MO-1226-SM-4DM5S GTEx Tissue Sample Gene Expression Profiles 1.0 1.19792 Specific developmental disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.638 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10185 GTEX-XYKS-1426-SM-4BRUO GTEx Tissue Sample Gene Expression Profiles 1.0 0.864569 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.64632 GSE120756_2_v_9_tet2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XYKS-2626-SM-4BRUT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12831 TRAPPC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2519 GTEX-QDT8-0426-SM-32PKZ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 Perturb_17171_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 apoptotic GeneRIF Biological Term Annotations 1.0 null C-4-I COSMIC Cell Line Gene Mutation Profiles 1.0 null Bone disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38679 superficial stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62883 alar plate of evaginated telencephalic vesicle Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51176 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.978385 PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.048588 GTEX-V1D1-2026-SM-3GAF4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.75385 immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041027 TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.588 GSE222598_1_v_0_sf3b4_human RummaGEO Gene Perturbation Signatures 1.0 null GSE68156_0_v_5_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null SNCA_KO_GDS4153_442_mouse_Cerebellum - 6 month GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.912968 Acute promyelocytic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.688 SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8426 G402 DepMap CRISPR Gene Dependency 1.0 3.49966 MDAMB361 DepMap CRISPR Gene Dependency 1.0 2.18508 PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX Rummagene Transcription Factor Associations 2026 1.0 null GAMG CCLE Cell Line Gene Expression Profiles -1.0 -2.10947 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.59537 deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69872 DU-145 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 embryonic structure TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PISD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17435 GTEX-OHPK-0426-SM-3MJH3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04436 Perturb_5695_KO_Tug1_SRP176442 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.6281 hsa-miR-711 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 GTEX-T8EM-1626-SM-3DB7K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.985263 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MMP17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45061 vasculitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.176757 ISCU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29859 Acute Myeloid Leukemia_LAML_TCGA-AB-2919-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null motoneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.553286 POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null lung cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058265 AGPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52159 superficial gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1207 GTEX-R55G-2526-SM-2TC6D GTEx Tissue Sample Gene Expression Profiles 1.0 0.933513 GTEX-X585-1226-SM-46MW7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.993992 GTEX-P4QT-1326-SM-3NMD3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861694 suppression GeneRIF Biological Term Annotations 1.0 null GTEX-OHPM-0726-SM-3LK7A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.863171 GTEX-P4PQ-0626-SM-3NMCU GTEx Tissue Sample Gene Expression Profiles 1.0 0.995262 m2 part of nucleus parabrachialis pigmentosus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45821 Medial preoptic nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64675 17660535-TableS4a GeneSigDB Published Gene Signatures 1.0 null cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.973394 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.765529 RAD21_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null diethylstilbestrol_mus musculus_gpl6887_gse37969 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061785 Perturb_17685_KO_Pgr_SRP365149 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.4114 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07 GTEX-Q2AI-1326-SM-2S1PL GTEx Tissue Sample Gene Expression Profiles 1.0 0.992985 GTEX-X4EO-2926-SM-4E3JH GTEx Tissue Sample Gene Expression Profiles 1.0 1.22722 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.58768 KHM1B CCLE Cell Line Gene CNV Profiles 1.0 1.77871 NCCSTCK140 CCLE Cell Line Gene Expression Profiles 1.0 3.40758 posteroventral (inferior) parietal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.862766 GTEX-X5EB-1426-SM-46MVW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67134 ZNF135 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.942 GTEX-PLZ5-0926-SM-3TW8L GTEx Tissue Sample Gene Expression Profiles 1.0 0.955964 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null negative regulation of cellular process GO Biological Process Annotations 2025 1.0 null PMC5732738-oncotarget-08-103415-s002.xlsx-CAMA1_DEGs-Genes_differentially_expressed_by_1_25_fold_between_parental_CAMA1_cells_and_GATA3_mutant_knock-in_clone_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null PMC6345883-41598_2018_37397_MOESM10_ESM.xlsx-AR_D0_VS_D7_W_B29__TRANS-Gene_Name_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE88819_5_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE169155_3_v_7_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.595656 GSE158969_1_v_0_trastuzumab_human RummaGEO Drug Perturbation Signatures 1.0 null GSE207514,GSE207515_2_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures 1.0 null H3K36me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.23364 PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.57421 neural plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7674 GTEX-WHSE-0011-R6A-SM-3P5ZP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3129 GTEX-PX3G-0126-SM-2I3EN GTEx Tissue Sample Gene Expression Profiles 1.0 1.6128 GTEX-S341-1226-SM-4AD5S GTEx Tissue Sample Gene Expression Profiles 1.0 1.19391 NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02802 H3K36me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNAPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25566 INPP5K CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01888 SNU503 CCLE Cell Line Gene Expression Profiles 1.0 1.43011 Perturb_3580_KD_UBE3A_SRP124518 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.79985 upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20899 CJM CCLE Cell Line Gene CNV Profiles -1.0 -1.65289 cytoplasm LOCATE Curated Protein Localization Annotations 1.0 null Perturb_17196_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.67451 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01983 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.60578 Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25761 abducens motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05717 Lung adenocarcinoma_LUAD_TCGA-50-5935-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.07668 GSE130437_2_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-W5X1-2526-SM-3GILC GTEx Tissue Sample Gene Expression Profiles 1.0 1.01715 TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-0126-SM-2S1NM GTEx Tissue Sample Gene Expression Profiles 1.0 0.907389 Developmental disorder of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.638 Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 Perturb_2798_KD_TRPS1_SRP125141 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05082 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Vagina TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 GTEX-XV7Q-2526-SM-4BRV9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01033 esophagus HPA Tissue Gene Expression Profiles 1.0 1.29594 inferior olive, dorsal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.991282 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-8580-01A-31R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86309 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46B-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.09851 PPP1R3E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84351 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPN-0011-R2A-SM-2I5FB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.830594 PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-OVOL2_OVOL2 Rummagene Transcription Factor Associations 2026 1.0 null GSE96641_5_v_2_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HSPA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27762 GTEX-R55C-0008-SM-48FCF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19264 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PX-01A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H3122 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 GSE161864,GSE161866_4_v_3_ror2_human RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESR1-26153859-MCF-7-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.488648 Perturb_17165_OE_ESR1_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.12123 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.97504 KMS11 DepMap CRISPR Gene Dependency 1.0 3.51566 LNZTA3WT4 DepMap CRISPR Gene Dependency 1.0 7.98838 GSE171175,GSE171181_1_v_0_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057979 GTEX-XUYS-0126-SM-47JWZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.14939 Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single-organism cellular process GO Biological Process Annotations 2015 1.0 null superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01492 MDAMB231 CCLE Cell Line Gene Expression Profiles -1.0 -1.61434 HOS COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 hsa-miR-3168 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE153189_1_v_0_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.63306 SW872 COSMIC Cell Line Gene Mutation Profiles 1.0 null 16912175-SuppTable3b GeneSigDB Published Gene Signatures 1.0 null Basic cell groups and regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76173 GSE166004_5_v_4_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.948261 Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54604 FAM118B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32706 bronchogenic carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065232 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.78285 GTEX-S4P3-1126-SM-4AD52 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17379 superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57503 RPL28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68985 MERO82 DepMap CRISPR Gene Dependency 1.0 2.75039 GTEX-XUZC-2126-SM-4BRW8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1614 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.924928 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.4163 mRNA_POU5F1_20526341 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null NT5DC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27466 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null striatum_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.926409 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04017 GIMEN DepMap CRISPR Gene Dependency 1.0 3.79403 GTEX-XBED-2226-SM-47JYQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.13685 GTEX-SUCS-1926-SM-32PM3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.69354 dorsolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.87494 Oral mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 Perturb_17170_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE130081,GSE130082_5_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6961-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDK7_knockdown_138_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.03448 GTEX-XMK1-1126-SM-4IHJ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35579 hippocampus HPA Tissue Protein Expression Profiles -1.0 -1.32825 8505C CCLE Cell Line Gene CNV Profiles -1.0 -1.34761 ESC_J1_UP_EARLY.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null GTEX-OIZH-1826-SM-2YUNP GTEx Tissue Sample Gene Expression Profiles -1.0 -2.25218 central nucleus of the inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1158 Perturb_17195_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 FOXA1-25329375-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null WM-266-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02845 SNRNP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20161 NCIH1623 CCLE Cell Line Gene CNV Profiles 1.0 1.85083 22RV1 DepMap CRISPR Gene Dependency 1.0 2.05067 adrenal_4c HPA Tissue Sample Gene Expression Profiles -1.0 -1.85091 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0953 Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25166 GSE113329,GSE113335_3_v_4_taf6l_mouse RummaGEO Gene Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.84203 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -1.7168 orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.915077 GTEX-QDVJ-0726-SM-48U1W GTEx Tissue Sample Gene Expression Profiles 1.0 0.865734 GTEX-XOTO-2126-SM-4B64U GTEx Tissue Sample Gene Expression Profiles 1.0 0.850984 GTEX-S7SF-1826-SM-3K2AD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0489 PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Supplementary_Table_9A_The_effects_of_whole_blood_transcripts_on_COVID-19_severity_with_suggestive_Mendelian_randomization_evidence_P_0_05_using_Genomicc_data_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.15734 BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902115 layer 2 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00437 Rectal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 NCOA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2933 GTEX-U4B1-0826-SM-4DXTW GTEx Tissue Sample Gene Expression Profiles 1.0 1.06188 Perturb_16440_KD_IL13RA2_SRP314695 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Charcot-Marie-Tooth disease type 1A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 binding GO Molecular Function Annotations 2015 1.0 null GTEX-W5WG-2226-SM-4LMI3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04315 TP63_01_200 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.88845 Cancer of prostate_Prostate_GSE1413 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.87408 GTEX-T8EM-0826-SM-4DM76 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.853827 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34778 WDHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74242 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4811 HBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28527 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.834656 CHURC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07205 POMGNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46857 PLEKHO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02851 Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.089715 GTEX-S7SE-0226-SM-2XCD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34806 MED8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74908 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15335 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44482 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03486 GSE231745_1_v_0_venetoclax_human RummaGEO Drug Perturbation Signatures 1.0 null USF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33388 GTEX-OXRK-1326-SM-3NB1A GTEx Tissue Sample Gene Expression Profiles 1.0 0.908927 GTEX-WH7G-2026-SM-3NMBL GTEx Tissue Sample Gene Expression Profiles 1.0 0.84007 EIF4G1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71878 CAMTA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15574 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE174383_2_v_7_ly6d_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE120413,GSE120447_4_v_5_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null L363 CCLE Cell Line Gene Expression Profiles 1.0 1.55763 layer 4 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10838 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null negative regulation of cell proliferation GO Biological Process Annotations 2015 1.0 null GTEX-S341-1726-SM-3K2AK GTEx Tissue Sample Gene Expression Profiles 1.0 2.10684 HERC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5783 Lung squamous cell carcinoma_LUSC_TCGA-21-1082-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE161864,GSE161866_1_v_3_ror2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE121824,GSE121826_0_v_6_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PLZ4-1626-SM-3P618 GTEx Tissue Sample Gene Expression Profiles 1.0 1.51715 GTEX-OIZG-1026-SM-3LK5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.992277 carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.248339 Perturb_15189_KD_TP63_SRP056637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 FZD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41738 CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0819 bnipl2 GeneRIF Biological Term Annotations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-06A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sirolimus_homo sapiens_gpl2895_gse16944 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Agranular insular area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15825 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1359 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.969585 GTEX-TSE9-0426-SM-3DB81 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25382 ZFP281-18757296-E14-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null SKNEP1 DepMap CRISPR Gene Dependency 1.0 3.11837 mRNA_SETDB1_19884255 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX Rummagene Transcription Factor Associations 2026 1.0 null PMC4046566__F2 PFOCR Pathway Figure Associations 2023 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neuroblastoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.04 GTEX-S7SE-0126-SM-2XCD5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37843 Prostate disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.042 ESR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1418 Tbx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.9287 mantle zone of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36794 layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.2951 Lung adenocarcinoma_LUAD_TCGA-86-8669-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.6348 GTEX-REY6-2426-SM-48FF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.928726 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.09796 ARID4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33574 GTEX-T5JW-1426-SM-4DM5Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.833903 Perturb_17188_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.3923 granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26633 Perturb_17166_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.8861 GTEX-S95S-0326-SM-4B66U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35754 GSE223008_5_v_2_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE213650_3_v_1_everolimus_human RummaGEO Drug Perturbation Signatures 1.0 null 496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.69732 ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09466 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053799 GTEX-REY6-0626-SM-2TF4G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14062 ventrolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13738 PMC4796178__F1 PFOCR Pathway Figure Associations 2023 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GF1-26923725-CHIP-SEQ-HPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.471555 cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04611 biological regulation GO Biological Process Annotations 2015 1.0 null GSE126621,GSE126920_1_v_0_dppa4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OHPL-0126-SM-2HMJ7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01861 TMEM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2618 trigeminal nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.77027 Bronchus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retrosplenial area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54604 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Placenta TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 tet1_21295276_mesc_v6.5_lof_mouse_gpl6887_gse26900 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.130195 ar_21330406_lncap_lof_human_gpl570_gds4113 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.098036 Perturb_17185_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06244 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null HEP-3B cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.302 u698 HPA Cell Line Gene Expression Profiles 1.0 1.46316 GSE200673,GSE200691_1_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.874894 SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.39117 PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-Genes_with_VDR_elements_only_control_VDR Rummagene Transcription Factor Associations 2026 1.0 null PFDN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86065 Integumentary system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.13341 Liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.013 GTEX-OOBK-0126-SM-2YUND GTEx Tissue Sample Gene Expression Profiles 1.0 1.12762 Retrosplenial area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1207 EGR1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1912 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42575 GSE96641_1_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01716 GTEX-QDVJ-1826-SM-2S1P3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04135 cytoplasmic part GO Cellular Component Annotations 2015 1.0 null OSR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47372 GTEX-QDT8-0126-SM-48TZ1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.883182 GTEX-R55C-1626-SM-48FEG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53866 cuneus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.36305 posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.967305 GTEX-S3XE-1626-SM-3K2AJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52155 SNU1214 CCLE Cell Line Gene Expression Profiles 1.0 1.84967 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.896201 NP2 DepMap CRISPR Gene Dependency 1.0 7.12983 organism form TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11998 Epimastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.939 GSE139966_1_v_2_figla_mouse RummaGEO Gene Perturbation Signatures 1.0 null retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11734 Penis_Foreskin_Fibroblast_Primary_Cells_skin02 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.84355 GTEX-QLQW-0626-SM-447A6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08799 GTEX-R55G-1026-SM-48FDI GTEx Tissue Sample Gene Expression Profiles 1.0 0.951891 KYSE-410 COSMIC Cell Line Gene Mutation Profiles 1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.913951 CAOV4 CCLE Cell Line Gene CNV Profiles 1.0 1.95017 PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U3ZM-0526-SM-4DXTB GTEx Tissue Sample Gene Expression Profiles 1.0 1.06035 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05939 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNRPF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24144 TE9 CCLE Cell Line Gene Expression Profiles 1.0 1.63252 GTEX-OHPL-1826-SM-2YUN8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57034 GTEX-TML8-1526-SM-4DXUX GTEx Tissue Sample Gene Expression Profiles 1.0 1.13233 Internal female genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 esophagus_5a HPA Tissue Sample Gene Expression Profiles 1.0 1.33708 Bed nuclei of the stria terminalis, anterior division, oval nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24314 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00927 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.42351 GTEX-RM2N-0726-SM-48FD5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.941674 smoothmuscle_8b HPA Tissue Sample Gene Expression Profiles -1.0 -0.865978 GSE149075_2_v_5_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null cycle GeneRIF Biological Term Annotations 1.0 null GTEX-OHPK-1626-SM-2YUN3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28721 primary motor-sensory cortex (samples)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.914425 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.55487 Lung transplant rejection_Trachea_GSE3418 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.12455 GTEX-XUJ4-0526-SM-4BOON GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873939 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37311 carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061932 KS1 CCLE Cell Line Gene Expression Profiles -1.0 -1.55249 MBD3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80658 Prdm15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.0603 ZNF438 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76549 CHLA57 DepMap CRISPR Gene Dependency 1.0 3.77481 GTEX-QEG4-1226-SM-2S1P6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21444 hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.970466 Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.46695 Adrenocortical carcinoma_ACC_TCGA-OR-A5JC-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE102870_1_v_2_nr1h4_human RummaGEO Gene Perturbation Signatures -1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.423 hepg2 HPA Cell Line Gene Expression Profiles -1.0 -1.12773 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.52269 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.87731 ZC3H8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02349 C2orf81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69433 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.99696 epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072361 postcentral gyrus, right, bank of the posterior central sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.48949 PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null UTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37856 ZNF281 ChEA Transcription Factor Targets 1.0 null CCNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08872 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.927813 Lung adenocarcinoma_LUAD_TCGA-44-A47A-01A-21R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 85.7565 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1245b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 primary motor cortex (area M1, area 4)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.85687 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.992619 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973604 GTEX-OIZH-1326-SM-3NB1H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14348 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23791 presence GeneRIF Biological Term Annotations 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.08221 corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.990637 OCIMY7 DepMap CRISPR Gene Dependency 1.0 3.56363 Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.639794 KU812 DepMap CRISPR Gene Dependency 1.0 2.86211 mda-mb-231 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236332 ventrolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.09008 primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.73932 hippocampus (hippocampal formation)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.29928 isthmus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13313 H3K36me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWS6-1126-SM-47JXC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08331 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31855 PTPN21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27875 SLC16A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15034 769-P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.967808 lung cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062181 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.949697 AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.42358 GSE116354,GSE117379_2_v_4_cox2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29554 GTEX-REY6-0326-SM-2TF5A GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.956484 Musculoskeletal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 ZNF229 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39342 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25925 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49663 GTEX-XYKS-1526-SM-4BRUP GTEx Tissue Sample Gene Expression Profiles 1.0 0.950487 GTEX-S4Q7-0626-SM-4AD5M GTEx Tissue Sample Gene Expression Profiles 1.0 1.07704 lung_3e HPA Tissue Sample Gene Expression Profiles 1.0 0.925691 Organism form TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL1_GRHL1 Rummagene Transcription Factor Associations 2026 1.0 null zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.15022 Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null SNU1327 DepMap CRISPR Gene Dependency 1.0 5.79161 MZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44446 Melanoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 WFIKKN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52593 GTEX-QDVJ-1926-SM-2S1PJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 GTEX-QV44-1926-SM-2S1RF GTEx Tissue Sample Gene Expression Profiles 1.0 1.63328 ST486 CCLE Cell Line Gene CNV Profiles 1.0 1.35025 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.29999 PMC12808183-41598_2025_31780_MOESM7_ESM.pdf-1-FOXN1_FOXN1 Rummagene Transcription Factor Associations 2026 1.0 null layer 3 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06957 V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.851828 Perturb_6519_KD_S100A4_SRP105051 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 COLO800 DepMap CRISPR Gene Dependency 1.0 2.64966 GTEX-WH7G-1526-SM-4LVMX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900071 DLD-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.920427 cytoplasm COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE80098,GSE80366_0_v_8_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null TMEM221 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31419 L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.972429 GTEX-XQ8I-0926-SM-4BOOF GTEx Tissue Sample Gene Expression Profiles 1.0 1.92401 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 HSF1-23293686-STHDH_STRIATAL-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.30879 Cerebellum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.36708 Lung squamous cell carcinoma_LUSC_TCGA-58-A46L-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Olfactory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34792 AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.74055 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.57106 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-V1D1-1026-SM-4JBHE GTEx Tissue Sample Gene Expression Profiles 1.0 1.06579 GABARAPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88535 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07889 Perturb_17178_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 TRMT9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.78002 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15507 RRN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88206 GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.931559 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HR-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCI38 DepMap CRISPR Gene Dependency 1.0 2.91432 GSE118077_7_v_2_sprr5_human RummaGEO Gene Perturbation Signatures 1.0 null mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null layer I of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.906701 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055179 Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28437 ABCC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65174 hsa-miR-582-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 intermediate stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61575 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NDST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15006 DBH_KO_GSE33906_53_mouse_heart (E10.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H2373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.71854 Inferior colliculus, external nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25751 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Penis_Foreskin_Keratinocyte_Primary_Cells_skin03 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.93417 Nucleus of the lateral olfactory tract, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32655 V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12598 GSE198165,GSE198166_5_v_3_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null regulation of growth GO Biological Process Annotations 2015 1.0 null posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.835621 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68532 GTEX-O5YW-0126-SM-3LK6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.10658 GTEX-SJXC-0426-SM-2XCFH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.82813 Orbital area, medial part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57848 GTEX-P4QT-1826-SM-2S1NJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01671 Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null GTEX-P4PP-1726-SM-2S1NS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.978295 FAM156B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02947 LHX8_Deficiency_GDS3254_600_mouse_Newborn ovaries GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ventral striatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24578 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR Rummagene Transcription Factor Associations 2026 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.74103 GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39958 Esophageal squamous epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.752 mantle zone of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47822 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW579 DepMap CRISPR Gene Dependency 1.0 2.07932 SARS-CoV NSP16_Day2_None_GSE49263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.5973 GTEX-RWSA-0126-SM-2XCBB GTEx Tissue Sample Gene Expression Profiles 1.0 1.18771 disease GWASdb SNP-Disease Associations 1.0 0.030234 GSE148066,GSE157787_8_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.918081 GSE230744,GSE237803_5_v_3_hira_human RummaGEO Gene Perturbation Signatures 1.0 null TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3945 ZNF722 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.81692 PMC5546320__F5 PFOCR Pathway Figure Associations 2023 1.0 null mRNA_MYC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null IFI6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45532 LK2 CCLE Cell Line Gene CNV Profiles 1.0 1.98906 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0611 GTEX-NFK9-1326-SM-3LK5I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17448 pathways GeneRIF Biological Term Annotations 1.0 null PPARG JASPAR Predicted Transcription Factor Targets 1.0 null LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30049 LB771HNC DepMap CRISPR Gene Dependency 1.0 6.98138 mantle zone of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04611 GTEX-PWCY-0426-SM-48TCW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04164 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 CIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22149 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75431 BCL2 Pathway Commons Protein-Protein Interactions 1.0 null PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.852989 METTL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05257 r10 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22991 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.99856 Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02784 H3K36me3_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.846033 Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X8HC-0126-SM-4E3JW GTEx Tissue Sample Gene Expression Profiles 1.0 0.880912 cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067458 Tongue-keratinocyte Tabula Sapiens Gene-Cell Associations 1.0 12.5786 primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18324 GTEX-U412-0526-SM-3DB9I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.77368 Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X62O-2226-SM-46MW3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33666 intermediate stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08518 CAOV4 DepMap CRISPR Gene Dependency 1.0 2.45136 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.937206 ZNF684 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.8061 GTEX-S7SF-1626-SM-3K2AY GTEx Tissue Sample Gene Expression Profiles 1.0 1.07643 GTEX-R55E-0008-SM-48FCG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11196 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10674 GTEX-TML8-1126-SM-4DXSS GTEx Tissue Sample Gene Expression Profiles 1.0 1.02345 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36932 GSE148066,GSE157787_11_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null KIF22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35798 SYNCRIP_KD_GDS3578_86_human_MM1S GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19404 GTEX-WOFM-1726-SM-3MJFA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73391 GATA1 ChEA Transcription Factor Targets 1.0 null regulation of growth rate GO Biological Process Annotations 2015 1.0 null GTEX-SJXC-0126-SM-2XCFF GTEx Tissue Sample Gene Expression Profiles 1.0 1.24373 KMS20 CCLE Cell Line Gene CNV Profiles 1.0 1.61589 RAPGEF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52136 GSE166004_5_v_6_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE155031_5_v_1_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null preopto-hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14907 GTEX-TKQ1-0226-SM-33HB5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.89506 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null esophagus_5c HPA Tissue Sample Gene Expression Profiles 1.0 1.38819 GTEX-X5EB-1926-SM-4E3IW GTEx Tissue Sample Gene Expression Profiles 1.0 1.06258 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00969 BMI1-19503595-MEFSC-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PDE10A_KO_GDS4542_292_mouse_hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NPIPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39135 MOLM-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null muscle cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.292616 Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.5429 GTEX-UPIC-0726-SM-3GADW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.917698 hep-3b cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.917779 GTEX-PWCY-1726-SM-48TD3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.920807 GSE140646_0_v_1_atf3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE146982_7_v_5_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QXCU-0926-SM-48FEP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3976 SW1271 CCLE Cell Line Gene CNV Profiles -1.0 -1.90678 MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03486 GTEX-WL46-0011-R10A-SM-3MJFQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.93755 GSE119978,GSE180930_6_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-R55D-1426-SM-48FEN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.93057 breast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.085292 H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4601-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Embryonic structure TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 Perturb_6689_KD_LAD1_SRP117048 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.16031 Acute Myeloid Leukemia_LAML_TCGA-AB-2950-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null apoptotic process GO Biological Process Annotations 2025 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36861 hsa-miR-4799-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 nucleus GO Cellular Component Annotations 2025 1.0 null Gall bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.442 TRMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23511 GTEX-XV7Q-1826-SM-4BRUV GTEx Tissue Sample Gene Expression Profiles 1.0 1.3766 Chronic kidney disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.2 ethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00212 GSE60837_6_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures 1.0 null transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.38113 GTEX-S95S-1226-SM-4GICG GTEx Tissue Sample Gene Expression Profiles 1.0 1.54478 Foxn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.7765 TOMM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22339 Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null XPOT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86531 GATA3 ENCODE Transcription Factor Targets 1.0 null USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0472 III Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.972797 BL-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.547 PRRT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46675 496100530_FWM_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.374 GSE111247_14_v_12_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.896646 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.71365 MAX_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prelimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29746 DKC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.59476 PMC6070710__F11 PFOCR Pathway Figure Associations 2024 1.0 null ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1500 CCLE Cell Line Gene Expression Profiles 1.0 1.68365 HCC1171 CCLE Cell Line Gene CNV Profiles 1.0 1.69402 GTEX-WRHU-1226-SM-4E3IJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.965996 Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.473 GTEX-WYVS-2126-SM-3NMA3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.30304 GTEX-S341-0526-SM-4AD5U GTEx Tissue Sample Gene Expression Profiles 1.0 1.02083 Ovary Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.970027 Cul4B-RING E3 ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.603 PMC10247733-41408_2023_863_MOESM2_ESM.pdf-43-BNC1_BNC1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YT-0226-SM-32PK5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51534 GTEX-SSA3-0126-SM-32QPU GTEx Tissue Sample Gene Expression Profiles 1.0 0.985572 Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC3153 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.811705 PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15 Rummagene Transcription Factor Associations 2026 1.0 null IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.949834 hsa-miR-483-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.26967 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.915089 H3K36me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VJYA-1326-SM-3GIJC GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 Mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 all GWASdb SNP-Phenotype Associations 1.0 0.03194 molecular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01494 GTEX-W5WG-1826-SM-4KL2Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.26805 HCC95 CCLE Cell Line Gene CNV Profiles -1.0 -1.58194 TEX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72645 H3K36me3_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hypb_Deficiency_GDS3641_523_mouse_Yolk sac from E10.5 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null dorsolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64326 HCA-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03404 LNZ308 CCLE Cell Line Gene CNV Profiles 1.0 2.16361 CSNK1E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64929 Liver Carcinoma DisGeNET Gene-Disease Associations 1.0 null periventricular stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1461 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03682 GTEX-XUJ4-2426-SM-4BOO3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32545 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PHTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02544 colonrectum_b HPA Tissue Sample Gene Expression Profiles -1.0 -1.08003 hippocampus (hippocampal formation)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.829789 lung TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055363 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HS-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Esophagus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 GTEX-T6MO-0526-SM-4DM6R GTEx Tissue Sample Gene Expression Profiles 1.0 1.09157 ZFX_KO_GDS2718_150_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null SURF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17824 YH13 CCLE Cell Line Gene Expression Profiles -1.0 -1.76407 GTEX-XQ3S-1526-SM-4BOOC GTEx Tissue Sample Gene Expression Profiles 1.0 1.17883 GTEX-P78B-2226-SM-3P5ZZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.846218 Perturb_13905_KD_DAZAP1_SRP102807 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.08064 496100522_PCx_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.29866 GTEX-T6MN-0011-R2A-SM-32QOW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.94111 TNPO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86957 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30168 GTEX-QLQW-0326-SM-447A8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16183 GTEX-XK95-1026-SM-4GIDV GTEx Tissue Sample Gene Expression Profiles 1.0 1.02102 MCF7 DepMap CRISPR Gene Dependency 1.0 3.34017 Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.27491 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062226 SU-DHL-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of PCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0913 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.995201 GTEX-SUCS-0726-SM-4DM7J GTEx Tissue Sample Gene Expression Profiles 1.0 0.979499 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.966896 SF126 CCLE Cell Line Gene CNV Profiles -1.0 -2.97068 r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43569 GSE198165,GSE198166_5_v_11_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-Q2AI-0226-SM-48U1D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.884 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A905-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.80058 H3K36me3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mammary myoepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.536 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.992619 OB glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83635 EB2 COSMIC Cell Line Gene Mutation Profiles 1.0 null MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53067 GTEX-QCQG-0626-SM-48U21 GTEx Tissue Sample Gene Expression Profiles 1.0 0.96735 endometrium_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.0776 GTEX-P4QR-0426-SM-2S1NV GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHSE-0926-SM-3NMBS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70525 HCC1937 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.952234 GTEX-TKQ1-1026-SM-4GICL GTEx Tissue Sample Gene Expression Profiles 1.0 1.45214 PAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00912 ZNF529 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05697 PMC7892341-41388_2020_1606_MOESM3_ESM.xlsx-Tables_S4-RNA-seq_LetR_only_AIB1_differentially_expressed_genes_not_present_in_MCF7_cells_Related_to_Figure_1_NCOA3 Rummagene Transcription Factor Associations 2026 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.18387 GTEX-VJYA-1126-SM-3GIJU GTEx Tissue Sample Gene Expression Profiles 1.0 1.21293 Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null apoptosis GeneRIF Biological Term Annotations 1.0 null GSE211241_1_v_0_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX Rummagene Transcription Factor Associations 2026 1.0 null epithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.482038 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19894 GSE114013,GSE114014_0_v_4_itraconazole_human RummaGEO Drug Perturbation Signatures 1.0 null golgi apparatus LOCATE Predicted Protein Localization Annotations 1.0 null viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053042 GTEX-SE5C-1126-SM-4BRWZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.294 GTEX-XOTO-0126-SM-4B66N GTEx Tissue Sample Gene Expression Profiles 1.0 1.14909 EP300 ENCODE Transcription Factor Targets 1.0 null Brain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 Internal female genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.035 GTEX-QV31-1326-SM-2S1QE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.891622 GFER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2025 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0779 Skin disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 RAB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12165 GTEX-XQ8I-0426-SM-4BOPO GTEx Tissue Sample Gene Expression Profiles 1.0 1.35743 GTEX-N7MT-1926-SM-3LK5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.1967 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DBTRG05MG CCLE Cell Line Gene CNV Profiles -1.0 -1.36592 GSE169155_3_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-X4EP-0626-SM-3P621 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40794 HCC89 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.861603 GTEX-QEL4-0526-SM-3GIJ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.96785 external cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43177 EXTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20968 SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.252 Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.12063 GTEX-WRHK-1426-SM-3MJF9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33506 GSE112860_3_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 6 of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02685 Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2721-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.062767 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19295 medial habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32189 CHAGOK1 CCLE Cell Line Gene Expression Profiles 1.0 2.04754 H3K36me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCPAP CCLE Cell Line Gene CNV Profiles -1.0 -2.25015 oculomotor nucleus, main part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31246 GTEX-XQ3S-1426-SM-4BOPR GTEx Tissue Sample Gene Expression Profiles 1.0 1.22751 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.56402 supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52917 GTEX-T8EM-1026-SM-3DB7M GTEx Tissue Sample Gene Expression Profiles 1.0 1.13715 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.82562 OV56 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.13974 496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.85379 Perturb_12219_KD_EPRS_SRP073504 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.3979 GTEX-X585-2426-SM-46MW2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05822 GTEX-WEY5-1926-SM-3GIL8 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 GTEX-XBED-1926-SM-47JYP GTEx Tissue Sample Gene Expression Profiles 1.0 1.1051 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040457 SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03486 GTEX-T5JW-1726-SM-3GADN GTEx Tissue Sample Gene Expression Profiles -1.0 -2.27112 GTEX-WL46-0011-R2A-SM-3LK6O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.964317 Perturb_255_OE_CCNE1_SRP400296 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Bronchoalveolar system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 isthmic alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11091 bch GeneRIF Biological Term Annotations 1.0 null SNW1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33929 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null MYC-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.173804 WDR33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06271 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE96641_5_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20153 cytoplasmic part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE178292_0_v_2_melphalan_human RummaGEO Drug Perturbation Signatures 1.0 null H3K36me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inhibit GeneRIF Biological Term Annotations 1.0 null orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.869046 H3K36me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-4676-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null CAL120 CCLE Cell Line Gene Expression Profiles -1.0 -1.90608 cytosol GO Cellular Component Annotations 2015 1.0 null layer 2 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.35767 SIN3A ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A65J-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X5EB-2226-SM-46MW4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.873953 SSX2IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07069 postcentral gyrus, right, bank of the central sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1961 inner CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.920993 GTEX-U4B1-0226-SM-4DXU8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02849 Posterior parietal association areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.84342 GTEX-PVOW-0126-SM-2XCFA GTEx Tissue Sample Gene Expression Profiles 1.0 1.08557 GTEX-UPK5-1226-SM-4IHL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.47251 hsa-miR-4486 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GSE169590_0_v_1_rptor_human RummaGEO Gene Perturbation Signatures 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.459 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23228 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IE-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null G118 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.826442 GTEX-X5EB-2426-SM-4E3HX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.892295 GTEX-U412-0326-SM-3DB9L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910081 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13011 GTEX-P44H-0226-SM-2XCEU GTEx Tissue Sample Gene Expression Profiles 1.0 0.844991 lateral part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13841 GSE133087_1_v_0_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QEG5-0626-SM-2S1PP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35721 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18239 MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.88516 GRHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3329 Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF750_KD_GDS4599_177_human_HaCaT keratinocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-1268b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 BMPR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71505 HIC1_01_205 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60424 Perturb_17199_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.22678 interacts GeneRIF Biological Term Annotations 1.0 null mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-XYKS-2126-SM-4E3IB GTEx Tissue Sample Gene Expression Profiles 1.0 0.83724 GTEX-PX3G-1426-SM-48U1J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.851133 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5232_KO_Bmal1_SRP213356 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Perturb_12048_KO_LSD1_SRP310135 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GTEX-XBEW-1426-SM-4AT4J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04584 496100529_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30324 A1207 CCLE Cell Line Gene CNV Profiles -1.0 -1.7925 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null HCC1187 DepMap CRISPR Gene Dependency 1.0 2.24073 GSE223008_5_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null RAB22A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1643 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.20775 GTEX-Q2AH-1626-SM-3GAF8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32907 GTEX-U4B1-0726-SM-4DXUA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.952619 GSE207582_2_v_1_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAB40AL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45827 GTEX-R55C-0826-SM-48FCL GTEx Tissue Sample Gene Expression Profiles 1.0 0.89752 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.857863 GTEX-XQ8I-1526-SM-4BOOH GTEx Tissue Sample Gene Expression Profiles 1.0 1.2777 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053519 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_OTX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HP-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null programmed cell death GO Biological Process Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESC_V6.5_UP_LATE.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.51781 digestive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063692 AMO1 CCLE Cell Line Gene CNV Profiles 1.0 2.59998 KBTBD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05638 regulators GeneRIF Biological Term Annotations 1.0 null MMRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40881 GSE207582_4_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null Epididymis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2 Rummagene Transcription Factor Associations 2026 1.0 null ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.09008 GTEX-UPK5-0426-SM-3GAEK GTEx Tissue Sample Gene Expression Profiles 1.0 1.03812 lateral hypothalamic area, tuberal part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01578 GTEX-OXRN-1726-SM-3NM9B GTEx Tissue Sample Gene Expression Profiles 1.0 1.36897 layer 3 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.0741 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0913 Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-A4WN-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X261-0126-SM-3NMD6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4527 cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.34777 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null apoptotic process GO Biological Process Annotations 2023 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VUSG-2326-SM-4KL1U GTEx Tissue Sample Gene Expression Profiles 1.0 1.31039 GSE246195,GSE246305_1_v_3_sin3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.880168 Apicolateral plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.993 GTEX-TSE9-2826-SM-4DXTF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48103 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.954901 Perturb_16830_KO_Cldn18_SRP096968 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 TT CCLE Cell Line Gene Expression Profiles 1.0 2.32101 PMC9195629-Table1.xlsx-Supplementary_Table_1-C-FOS_FOS Rummagene Transcription Factor Associations 2026 1.0 null Prostate carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.042 HS688AT CCLE Cell Line Gene Expression Profiles -1.0 -2.11309 Perturb_17197_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.190113 hsa-miR-513a-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.219115 placenta TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-SIU8-0426-SM-4BRUE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38926 hsa-miR-4537 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Embryonic structure TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-QDT8-0226-SM-32PL4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963874 GTEX-OIZG-0726-SM-33HBL GTEx Tissue Sample Gene Expression Profiles 1.0 1.54961 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null skin_5f HPA Tissue Sample Gene Expression Profiles 1.0 1.81787 Retrosplenial area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6807 GTEX-XGQ4-2426-SM-4AT55 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935442 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.32817 C5orf24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35735 lateral anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2748 LIG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12341 GTEX-WFJO-1926-SM-3GILA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.943234 secondary prosencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49064 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100535_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.55275 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.942 GTEX-VJYA-0726-SM-4KL1T GTEx Tissue Sample Gene Expression Profiles 1.0 1.09458 NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.939762 CAOV3 DepMap CRISPR Gene Dependency 1.0 3.47367 regulation of cell population proliferation GO Biological Process Annotations 2023 1.0 null GSE174383_2_v_5_ly6d_mouse RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05552 GTEX-SIU8-0126-SM-2XCDT GTEx Tissue Sample Gene Expression Profiles 1.0 0.983268 Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null trigeminal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.717882 Perturb_11972_KO_Soat1_SRP235547 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.3694 Medial geniculate complex, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66045 skin_6a HPA Tissue Sample Gene Expression Profiles 1.0 1.78057 hsa-miR-1827 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null periventricular stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27841 WHSC1 ENCODE Transcription Factor Targets 1.0 null cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2352 nucleus GO Cellular Component Annotations 2023 1.0 null GSE223287,GSE223290_2_v_4_braf_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nucleus of the lateral olfactory tract, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20429 BONNA-12 COSMIC Cell Line Gene Mutation Profiles 1.0 null KDM5A ENCODE Transcription Factor Targets 1.0 null neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069971 GSE108500_1_v_0_foxp1_human RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU3F4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80789 Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.7018 lung disease GWASdb SNP-Disease Associations 1.0 0.526067 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07715 RERFGC1B CCLE Cell Line Gene Expression Profiles 1.0 1.57063 GTEX-R55D-0008-SM-48FEV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.847736 Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.635 mRNA_NR2F2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Perturb_9596_KO_Prox1_SRP176286 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.04579 Male reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.042 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cytosol COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.943922 PMC6345883-41598_2018_37397_MOESM10_ESM.xlsx-AR_D0_VS_D14__TRANS-Gene_Name_AR Rummagene Transcription Factor Associations 2026 1.0 null FAM3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66545 PMC12454715-13555_2025_1471_MOESM1_ESM.pdf-112-ZFP42_ZFP42 Rummagene Transcription Factor Associations 2026 1.0 null PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.872617 CAL120 CCLE Cell Line Gene CNV Profiles -1.0 -1.57795 GTEX-RWSA-0526-SM-2XCBC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.831213 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.830273 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052889 GSE145915_5_v_4_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null JMY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63806 dorsal preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40414 lower respiratory tract disease GWASdb SNP-Disease Associations 1.0 0.184592 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20728 abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.094726 OVCAR-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911645 smoothmuscle_8c HPA Tissue Sample Gene Expression Profiles -1.0 -1.23372 NME2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WYJK-0426-SM-3NM9G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10046 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.379499 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04362 SW756 COSMIC Cell Line Gene Mutation Profiles 1.0 null Central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 long insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.868325 SW1116 CCLE Cell Line Gene CNV Profiles -1.0 -1.40561 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AH-2026-SM-2S1PX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 cranial nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.516891 dorsal part of alar p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36794 GSE159937_1_v_0_tfcp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.13604 smooth muscle cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.51842 MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-WHSB-1326-SM-3LK6W GTEx Tissue Sample Gene Expression Profiles 1.0 1.77294 Skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 Perturb_17173_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.719 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23042 t70-white-adipose_consensus MoTrPAC Rat Endurance Exercise Training 1.0 2.71779 Skeletal muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 GTEX-X638-0126-SM-47JZ8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.91786 GTEX-QLQ7-0926-SM-447BC GTEx Tissue Sample Gene Expression Profiles 1.0 0.937695 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061316 GATA1-19941827-MEL-MOUSE ChEA Transcription Factor Targets 2022 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Apocrine sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.646 Trigeminal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80861 GSE60837_0_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-NPJ8-0126-SM-2YUNR GTEx Tissue Sample Gene Expression Profiles 1.0 1.13791 superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68487 primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.45217 GTEX-WFON-0826-SM-4LVMI GTEx Tissue Sample Gene Expression Profiles 1.0 0.869358 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062097 OUMS23 CCLE Cell Line Gene Expression Profiles 1.0 1.76737 HOXB7_01_170 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.7058 GSE143499_0_v_1_gata6_human RummaGEO Gene Perturbation Signatures 1.0 null H3K36me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8458 FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-N7MS-0626-SM-2YUN7 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.01645 SARS-CoV MA15_Day7-C57BL6_None_GSE50878 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.96522 PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D9_vs_D15-Unnamed_4_CENPX Rummagene Transcription Factor Associations 2026 1.0 null oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19232 intermediate part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03134 GALNT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00296 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.973628 JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9575 liver cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.095453 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.93055 ODAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74196 GSE112202_5_v_2_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.9502 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EOMES-20176728-TSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-TKQ1-1226-SM-4GICJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.91168 hsa-miR-3142 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.5519 Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QCQG-1726-SM-3GIJ9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21012 non-small cell lung cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.091427 striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.93102 smallintestine_4d HPA Tissue Sample Gene Expression Profiles -1.0 -1.85091 superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42517 GTEX-TMZS-0126-SM-3DB9Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.13955 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null esophagus GTEx Tissue Gene Expression Profiles 1.0 0.980296 Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DPP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2228 lingual gyrus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06003 r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96931 TBCCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16422 skin HPA Tissue Gene Expression Profiles 1.0 1.75391 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01266 Lung squamous cell carcinoma_LUSC_TCGA-77-8133-01A-12R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.538967 Perturb_7769_KD_Y14_DRP003223 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.24405 cell part LOCATE Curated Protein Localization Annotations 1.0 null MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6077 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26513 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.47441 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TIMM23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35715 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15733 RASA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47658 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 TP63 JASPAR Predicted Transcription Factor Targets 1.0 null NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30434 DMRTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27689 GTEX-U8XE-1226-SM-4E3HN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.69956 CEBPB-24764292-MC3T3-MOUSE ChEA Transcription Factor Targets 2022 1.0 null layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.61614 intracellular part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 SPPL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24676 GTEX-WFG7-1126-SM-4LMK3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.912037 MT-ND5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08046 Adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 GTEX-QEG5-0326-SM-2S1PB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.977169 GTEX-S4P3-0326-SM-4AD6P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63846 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.19803 GPATCH4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74828 periventricular stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05717 GSE105781_1_v_0_grhl2_mouse RummaGEO Gene Perturbation Signatures -1.0 null OST4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20251 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-11A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.40368 Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NK-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.898893 EIF4G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13021 ZNF521 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81436 NCIH526 CCLE Cell Line Gene CNV Profiles 1.0 1.34397 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0819 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055781 zona incerta Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.933177 hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044123 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, trunk, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35135 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.04831 U-698-M COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 GTEX-X4XY-1726-SM-46MVO GTEx Tissue Sample Gene Expression Profiles 1.0 1.44396 KIAA0753 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38255 GTEX-WFON-2126-SM-3LK7O GTEx Tissue Sample Gene Expression Profiles 1.0 1.59086 H3K36me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2911-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.04 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.237706 GTEX-XPVG-2926-SM-4B66G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09432 Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.464 NAV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24041 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.63725 cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36932 Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.2862 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontal operculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.870967 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC95 DepMap CRISPR Gene Dependency 1.0 2.71426 PAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1649 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.00127 interacting GeneRIF Biological Term Annotations 1.0 null Thioglucosidase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.627 CHD1 ENCODE Transcription Factor Targets 1.0 null Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 52.6951 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERF::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9569 GTEX-PLZ5-1826-SM-3NB22 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16006 habenula (old epithalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36459 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 11823860-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null Taproot TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.546 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64347 PFSK1 DepMap CRISPR Gene Dependency 1.0 3.02901 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.52328 HSC-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.30881 Perturb_17192_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.301 GSE120413,GSE120447_0_v_5_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24554 MNT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39309 GTEX-T5JC-0426-SM-32PLO GTEx Tissue Sample Gene Expression Profiles 1.0 0.912069 GTEX-OXRL-0126-SM-2YUMP GTEx Tissue Sample Gene Expression Profiles 1.0 0.875836 r10 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02986 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PYCR1 Pathway Commons Protein-Protein Interactions 1.0 null Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.638 INSIG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9587 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null Nasopharynx epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.751 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.44011 PSENEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34034 GTEX-Q2AH-0826-SM-48TZN GTEx Tissue Sample Gene Expression Profiles 1.0 0.917137 lateral hypothalamic area, mammillary region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3605 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null gyrus rectus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.828495 GSE148066,GSE157787_0_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05068 striatum_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.73932 APP_KO_GDS4414_370_mouse_prefrontal cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13902 GTEX-S4P3-0726-SM-4AD57 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19979 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32363 GSE146982_7_v_5_gpd1_human RummaGEO Gene Perturbation Signatures -1.0 null BCL2 Hub Proteins Protein-Protein Interactions 1.0 null H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE74251_0_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-REY6-0726-SM-2TF4M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34984 cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-U3ZN-2526-SM-3DB7V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17141 TEDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4344 GSE116299_4_v_3_folic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.629956 breast cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.299601 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.08336 Prostate adenocarcinoma_PRAD_TCGA-V1-A8MK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07889 ZFP281-18757296-E14-MOUSE ChEA Transcription Factor Targets 2022 1.0 null regulation of cellular process GO Biological Process Annotations 2015 1.0 null GTEX-R55E-0126-SM-2TC5Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.858047 Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null non-small cell lung cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071059 PMC5546320__F5 PFOCR Pathway Figure Associations 2024 1.0 null intermediate stratum of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11416 FOXA1 ENCODE Transcription Factor Targets 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.90097 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.977733 dorsolateral part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04833 intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null GTEX-WL46-0326-SM-3LK6Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07819 skin TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-WY7C-2126-SM-3NB2R GTEx Tissue Sample Gene Expression Profiles 1.0 1.31519 GTEX-P4PP-0126-SM-3LK69 GTEx Tissue Sample Gene Expression Profiles 1.0 1.5279 Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.717528 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null oculomotor nucleus, Edinger-Westphal subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.63403 OB mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18239 CMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89511 GTEX-X4EP-0126-SM-3P5YV GTEx Tissue Sample Gene Expression Profiles 1.0 1.39767 GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6219 olfactory bulb, principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47822 HSF1-23293686-STHDH-STRIATAL-MOUSE ChEA Transcription Factor Targets 2022 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.031999 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08688 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bone remodeling disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.923 SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.20344 VPS9D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82341 m1B part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28845 GTEX-OXRO-1926-SM-2S1O3 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.67765 Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.888963 ventral subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32529 H3K36me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12127 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 hsa-miR-3159 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GSE130437_0_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Mammary luminal epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.561 GSE232631_4_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary auditory cortex (core)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18445 Dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02805 SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.861603 CDC42 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QEG5-1426-SM-447AS GTEx Tissue Sample Gene Expression Profiles 1.0 0.864446 SKLMS1 CCLE Cell Line Gene CNV Profiles -1.0 -2.28823 hsa-miR-4533 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GSE153907,GSE153908_0_v_1_azathioprine_human RummaGEO Drug Perturbation Signatures 1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.78637 GSE198165,GSE198166_9_v_11_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE210885_2_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.11012 GTEX-Q2AG-0526-SM-2S1PW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11582 GTEX-VJWN-0126-SM-3GIK7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00585 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01924 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062904 eosinophilia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.273664 superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01793 GTEX-PWN1-0626-SM-48TDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.25077 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14928 H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-P4QS-0008-SM-48TDY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.826508 GTEX-S95S-0426-SM-4B64I GTEx Tissue Sample Gene Expression Profiles 1.0 0.902324 NCIH1650 DepMap CRISPR Gene Dependency 1.0 2.04349 KMS34 DepMap CRISPR Gene Dependency 1.0 3.15153 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19066 GTEX-UJMC-0226-SM-4IHLH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.84073 PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5 Rummagene Transcription Factor Associations 2026 1.0 null AVL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15831 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.872428 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BI-01B-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.90171 mantle zone of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09243 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KNS60 CCLE Cell Line Gene Expression Profiles -1.0 -1.61873 GTEX-O5YT-0126-SM-48TBW GTEx Tissue Sample Gene Expression Profiles 1.0 0.909599 Nkx3-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.7778 primary auditory cortex (core)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.11182 GSE139966_4_v_3_figla_mouse RummaGEO Gene Perturbation Signatures -1.0 null outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40278 H3K36me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_16302_KO_Esr1_SRP115139 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.47965 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HG-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DACH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10298 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18445 GNRH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66869 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A51X-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-485-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 GTEX-X4XY-0011-R8A-SM-46MVC GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16945 amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.923381 dorsal subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87713 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8956 PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.186 GSE199255,GSE199356_4_v_2_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null mRNA_KLF4_18264089 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC6070710__F11 PFOCR Pathway Figure Associations 2023 1.0 null PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1 Rummagene Transcription Factor Associations 2026 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.977879 Lung adenocarcinoma_LUAD_TCGA-97-A4M0-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null u266 HPA Cell Line Gene Expression Profiles 1.0 1.04844 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.919086 DTX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09469 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.45667 COPS7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43988 primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.928072 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23179 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14667 GSE92614_1_v_0_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23058 Prostate adenocarcinoma_PRAD_TCGA-HC-8260-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BMI1-19503595-MEFC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null cdc42gap GeneRIF Biological Term Annotations 1.0 null type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.567403 mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GSE135030_11_v_0_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1226 MFM-223 COSMIC Cell Line Gene Mutation Profiles 1.0 null peripheral nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06922 Perturb_5136_KD_Dax1_SRP311833 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.77229 PREPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31599 Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.998243 CDC42 Hub Proteins Protein-Protein Interactions 1.0 null GSE107505_3_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SKLU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.52021 GTEX-QVJO-1626-SM-2S1QW GTEx Tissue Sample Gene Expression Profiles 1.0 1.32122 GTEX-SNOS-0626-SM-4DM5F GTEx Tissue Sample Gene Expression Profiles 1.0 0.88002 vagina GTEx Tissue Gene Expression Profiles 1.0 1.2342 TEKTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.064 GSE145215_2_v_1_krt13_mouse RummaGEO Gene Perturbation Signatures 1.0 null Ovary TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.924798 GTEX-T6MO-1626-SM-32QOM GTEx Tissue Sample Gene Expression Profiles 1.0 1.31644 skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.486716 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE148066,GSE157787_3_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.072366 GSE210580_3_v_11_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.79961 cerebellar cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.07718 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86758 peripheral nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.168283 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.96815 Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.974411 TET1-21451524-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null UBTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29818 ZNF750_KD_GSE38039_696_human_HaCaT keratinocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX Rummagene Transcription Factor Associations 2026 1.0 null skin_5e HPA Tissue Sample Gene Expression Profiles 1.0 1.76502 PMC11952327-media-1.pdf-3-ENSG00000168348_INSM2 Rummagene Transcription Factor Associations 2026 1.0 null Main olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45088 GATA1-19941827-MEL-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.448742 CENPF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05055 mRNA_ZFX_17448993 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null 18387200-Genes GeneSigDB Published Gene Signatures 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE175787_13_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null HUPT4 CCLE Cell Line Gene CNV Profiles -1.0 -2.07951 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01001 organelle GO Cellular Component Annotations 2015 1.0 null GTEX-XOT4-0626-SM-4B66L GTEx Tissue Sample Gene Expression Profiles 1.0 1.54498 GTEX-U8T8-0326-SM-3DB93 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2591 epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059753 sensory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214017 ARHGAP1 Pathway Commons Protein-Protein Interactions 1.0 null Hindbrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 primary motor cortex (area M1, area 4)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.62232 GSE242290_3_v_0_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80744 TFAP2C_01_53 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.71638 HSFX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13768 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15705 GTEX-PWOO-2426-SM-2S1OV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12076 GTEX-XAJ8-0826-SM-47JY6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1725 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.88201 thorax TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07735 dorsolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.852889 TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-O5YT-1826-SM-32PK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52317 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.76746 GTEX-S4Z8-1826-SM-3K2BH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.827772 TMEM231 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1839 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null root Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75594 integument TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09005 Hak TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.52 SGO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32608 ERH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11025 SCC9 CCLE Cell Line Gene Expression Profiles 1.0 1.52163 primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08048 VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42376 Reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.042 GSE123638,GSE123639_2_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-U3ZH-2026-SM-3DB78 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15203 NCIH2887 DepMap CRISPR Gene Dependency 1.0 2.36272 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.4836 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11274 GSE222047_0_v_1_imidazole_human RummaGEO Drug Perturbation Signatures 1.0 null r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.27107 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.826442 GTEX-WK11-2726-SM-3NMAQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.06313 GTEX-U412-2026-SM-4DXSI GTEx Tissue Sample Gene Expression Profiles 1.0 0.911488 Autonomic nervous system neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.04 ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91841 GSE135705_5_v_3_corticosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-U3ZN-0226-SM-3DB8D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870468 GSE239578_2_v_3_cxadr_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100494_HIP_no dementia_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20414 cell death GO Biological Process Annotations 2015 1.0 null hsa-miR-3616-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 hsa-miR-4670-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01255 LRRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28007 NOS-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 IRAK2_knockout_76_GSE24264 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.20015 intracellular part LOCATE Curated Protein Localization Annotations 1.0 null GTEX-X8HC-0626-SM-4E3HQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.847788 type ii diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.483421 Lung adenocarcinoma_LUAD_TCGA-MP-A5C7-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S32W-2426-SM-2XCAT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.948813 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.834498 Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.317909 GTEX-OIZG-0926-SM-3LK5Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841537 cSARS Bat SRBD_60Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.29999 GTEX-WH7G-0926-SM-4LVMJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.882947 Medial geniculate complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44207 Perturb_13229_OE_Klf5_SRP341620 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.1358 GTEX-R55E-1326-SM-48FCR GTEx Tissue Sample Gene Expression Profiles 1.0 0.904329 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OACP4C COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 CASKI DepMap CRISPR Gene Dependency 1.0 3.10981 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08591 fetus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SP1 ENCODE Transcription Factor Targets 1.0 null periventricular stratum of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40236 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8878 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.11215 AGPAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65273 PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.991182 GTEX-RWSA-0626-SM-2XCBD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03424 USF2 ENCODE Transcription Factor Targets 1.0 null GTEX-WEY5-1126-SM-4LMIE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26172 CAPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24036 GTEX-OIZI-0626-SM-2XCEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11173 Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R53T-1126-SM-48FD4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01861 Inferior colliculus, dorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39962 HOS CCLE Cell Line Gene CNV Profiles 1.0 1.56342 Dorsal nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09461 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-W5WG-1626-SM-4LMKG GTEx Tissue Sample Gene Expression Profiles 1.0 1.11021 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.0789 POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040922 GTEX-QCQG-0126-SM-48U27 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.879561 SIRT4_KO_GDS4823_30_mouse_hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HSF1 ChEA Transcription Factor Targets 1.0 null H3K36me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CCLFPEDS0001T DepMap CRISPR Gene Dependency 1.0 2.15526 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15513 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052383 JURKAT DepMap CRISPR Gene Dependency 1.0 3.99858 NCIH1568 CCLE Cell Line Gene CNV Profiles 1.0 1.4393 Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.266926 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r3 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15124 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.94679 Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.40193 Skin TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 Perturb_16439_KD_IL13RA1_SRP314695 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QESD-0526-SM-2I5G5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.95695 DHRS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37594 ZNF703 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00506 PTPN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20056 parietal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08892 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052318 Purkinje cell layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06479 Lung adenocarcinoma_LUAD_TCGA-05-4384-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZN-2326-SM-3DB7W GTEx Tissue Sample Gene Expression Profiles 1.0 2.06378 hsa-miR-1273 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.73785 CTCF ENCODE Transcription Factor Targets 1.0 null GTEX-PX3G-1026-SM-48TZW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.958808 GSE219103,GSE219104_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15585 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22803 CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.56739 superficial stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13579 GTEX-X4XY-0326-SM-46MVZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15469 CCRF-CEM COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC4412144__F3 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-S3XE-0126-SM-4AD4R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.875957 Carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.042 ERG ChEA Transcription Factor Targets 1.0 null HCC1937 CCLE Cell Line Gene CNV Profiles -1.0 -2.48075 SIRT4_KO_GDS4823_505_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Anus disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.118 LBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36953 GSE132948,GSE132949_2_v_3_msi2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-U3ZN-1726-SM-4DXUQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.881628 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE239844_4_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35458 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0819 GTEX-XAJ8-1426-SM-47JYM GTEx Tissue Sample Gene Expression Profiles 1.0 1.66596 Esophagus Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 2.86486 HDAC2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYBL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7299 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.44857 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.29193 PMC7318773__F3 PFOCR Pathway Figure Associations 2023 1.0 null caudal secondary prosencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5074 GTEX-WFG8-0726-SM-3GILP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05163 primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.86153 amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12487 GTEX-R55C-0726-SM-48FCN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21013 Brain stem TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 dorsal part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40178 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWCY-0826-SM-48TCR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3788 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11377 BT483 CCLE Cell Line Gene Expression Profiles 1.0 1.93336 RBMS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59716 TMEM150A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40047 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055105 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null TMEM200C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.25824 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cranial nerve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.16093 Nervous system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.04 GTEX-PSDG-1326-SM-48TD2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.829224 H3K36me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GAK COSMIC Cell Line Gene Mutation Profiles 1.0 null EVSAT DepMap CRISPR Gene Dependency 1.0 3.24395 BCL2L1 Pathway Commons Protein-Protein Interactions 1.0 null nci-h226br cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.519253 GTEX-S3XE-0526-SM-4AD4G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39443 496100507_FWM_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03439 appendices_4b HPA Tissue Sample Gene Expression Profiles -1.0 -1.85091 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5466 downregulated GeneRIF Biological Term Annotations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31552 Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_downreg_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WYJK-0126-SM-3NMAB GTEx Tissue Sample Gene Expression Profiles 1.0 1.50947 e1b GeneRIF Biological Term Annotations 1.0 null OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23908 GSE157383_0_v_1_abemaciclib_human RummaGEO Drug Perturbation Signatures 1.0 null FBXW8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01481 inner CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1857 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.68009 striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.62295 Peripheral nervous system neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.04 alar plate of m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04379 vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049709 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null ADAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69398 though GeneRIF Biological Term Annotations 1.0 null GSE198165,GSE198166_0_v_3_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.40121 GTEX-XPVG-2126-SM-4B667 GTEx Tissue Sample Gene Expression Profiles 1.0 1.51212 U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.21318 posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21458 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H3K27ac_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XUJ4-1026-SM-4BOPB GTEx Tissue Sample Gene Expression Profiles 1.0 0.824995 Perturb_10387_OE_DRP1_SRP333953 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SIU8-0226-SM-2XCDS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.9364 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.77154 HEL DepMap CRISPR Gene Dependency 1.0 2.89475 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68392 GTEX-U8T8-0126-SM-3DB94 GTEx Tissue Sample Gene Expression Profiles 1.0 0.857082 layer 1 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08407 GTEX-V1D1-2226-SM-3NMAX GTEx Tissue Sample Gene Expression Profiles 1.0 1.04213 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30049 Peripheral nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.04 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06706 HCC70 CCLE Cell Line Gene Expression Profiles 1.0 1.38244 Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.914015 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48165 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00933 Nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 OTT1_KO_GDS4315_146_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null liver TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.073763 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.877106 EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null upregulated GeneRIF Biological Term Annotations 1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12557 hsa-miR-4284 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 TET1-21451524-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XBEC-0326-SM-4AT4M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07402 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SE5C-1226-SM-4BRWV GTEx Tissue Sample Gene Expression Profiles 1.0 1.09957 GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4333 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057137 parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.997149 18801183-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-SNMC-1226-SM-2XCFP GTEx Tissue Sample Gene Expression Profiles 1.0 1.45125 GSE65617_5_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.011923 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0387 PRDM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13976 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WN-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE193351_1_v_0_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null NKX2-5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4359 bone marrow HPA Tissue Protein Expression Profiles -1.0 -2.36012 outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10234 GK_KO_GDS1555_127_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC1438 CCLE Cell Line Gene Expression Profiles -1.0 -1.71064 H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.082 RAP1GAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57717 GTEX-WHSE-0011-R3A-SM-3P5ZM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.833596 GTEX-QXCU-1926-SM-48FE4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993981 GTEX-OIZH-3026-SM-3NB1G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.882346 PGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00578 mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null GTEX-NFK9-0226-SM-2HMKQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.79747 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041164 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08281 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.99847 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.41184 GSE216043_10_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Basal node TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.658 GTEX-XUJ4-0626-SM-4BOOO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835831 proliferationrelated GeneRIF Biological Term Annotations 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.191377 orbital frontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.66695 posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.45886 Churg-Strauss syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.014 GTEX-QLQW-1126-SM-2S1Q8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.978883 BMI1 ChEA Transcription Factor Targets 1.0 null GATA3_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin melanoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.835621 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062081 GTEX-RN64-1026-SM-48FDX GTEx Tissue Sample Gene Expression Profiles 1.0 1.34086 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.97161 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.842687 OMC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.9248 BCS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86374 striatum_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.45217 JHH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.17401 ventral tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09026 CR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64031 mRNA_MYOD1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-U8XE-0326-SM-3DB8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.01769 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.43391 SIPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20581 CALU-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11611 SNU-398 COSMIC Cell Line Gene Mutation Profiles 1.0 null t47d HPA Cell Line Gene Expression Profiles 1.0 2.7193 PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S6.xlsx-EMP_CREB_Targets-symbol_CREB1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OHPK-0326-SM-2HMJO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.931893 Lung squamous cell carcinoma_LUSC_TCGA-60-2711-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1395 CCLE Cell Line Gene CNV Profiles 1.0 2.16557 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null outer CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.851809 GTEX-XPVG-2626-SM-4B669 GTEx Tissue Sample Gene Expression Profiles 1.0 1.63854 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GTEX-WI4N-1026-SM-3LK7N GTEx Tissue Sample Gene Expression Profiles 1.0 0.871796 Perturb_7880_KD_INTS11_SRP266190 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.21335 beta GeneRIF Biological Term Annotations 1.0 null ventral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74484 GTEX-U3ZN-1626-SM-4DXTZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.86179 nucleus subputaminalis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.969519 P2URK562 DepMap CRISPR Gene Dependency 1.0 2.13767 PNMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54856 LAYN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43625 mRNA_MEF2C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null OPM2 CCLE Cell Line Gene CNV Profiles 1.0 1.50381 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04012 PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR Rummagene Transcription Factor Associations 2026 1.0 null BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15585 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null COLO-824 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 GTEX-T2IS-0011-R5A-SM-32QP4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38137 hsa-miR-4761-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 hsa-miR-1228 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Posterior parietal association areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47018 GTEX-XMD3-0008-SM-4AT4V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.885089 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4378 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.11723 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.28155 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4366019-pone.0116096.s005.xlsx-Primary_positives_NOT_retested-Unnamed_8_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08357 PRPF39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9343 ADAMTSL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56831 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.44825 H3K36me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01565 KG-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.674 TE-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null bcl2 GeneRIF Biological Term Annotations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2934-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.992619 EBC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.73593 GSE217405_3_v_2_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00189 ZNF681 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30909 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.19692 Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.248339 Bed nuclei of the stria terminalis, anterior division, anterolateral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51848 DMS-273 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 lymph node HPA Tissue Protein Expression Profiles -1.0 -1.32825 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5932 GTEX-RWSA-1426-SM-47JXA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855084 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of m1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.2578 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051229 Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWN1-2026-SM-48TD9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33919 GSE210885_0_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null nucleus GO Cellular Component Annotations 2015 1.0 null GTEX-POYW-1326-SM-48TCG GTEx Tissue Sample Gene Expression Profiles 1.0 1.4234 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.949254 GTEX-QEL4-1426-SM-447AC GTEx Tissue Sample Gene Expression Profiles 1.0 0.908305 CL-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.844679 gfer GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCNN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06671 BORCS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32751 MALME3M DepMap CRISPR Gene Dependency 1.0 3.0054 GTEX-WRHU-2826-SM-3MJG8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25784 CEP57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70613 GTEX-OIZH-0626-SM-3NB1L GTEx Tissue Sample Gene Expression Profiles 1.0 0.930638 Complement component C1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.817 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.909058 Periodontal ligament cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.626 GEMIN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43431 GSE199660_1_v_2_secretin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XXEK-0326-SM-4BRVV GTEx Tissue Sample Gene Expression Profiles 1.0 1.09157 mcf7 HPA Cell Line Gene Expression Profiles 1.0 0.948917 GTEX-OXRP-0926-SM-48TC1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.5039 Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0576 GTEX-RVPU-2226-SM-2XCAQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.08544 LARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.04288 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25055 SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01312 GTEX-Q2AI-0626-SM-48TZU GTEx Tissue Sample Gene Expression Profiles 1.0 0.866043 layer 2 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.97563 primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.886999 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.18299 forebrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42808 ZNF282 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.7034 dorsolateral prefrontal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.58768 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0794 MRPL35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88123 IPC298 CCLE Cell Line Gene Expression Profiles -1.0 -1.98659 Ventral tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17566 NCIH2126 DepMap CRISPR Gene Dependency 1.0 3.92473 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of higher mental function GWASdb SNP-Phenotype Associations 1.0 0.268418 GTEX-U8XE-0426-SM-3DB91 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48252 EGR1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.4278 GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972161 SLC25A15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12684 pten GeneRIF Biological Term Annotations 1.0 null GSE224547_1_v_0_cftr_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-P4PP-0726-SM-3NM9S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39067 Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.9193 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.26846 SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37901 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A719-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3195 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 NOP56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01203 salivarygland_6a HPA Tissue Sample Gene Expression Profiles 1.0 0.917319 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null primary auditory cortex (core)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32485 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.26465 subethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30749 SNU489 CCLE Cell Line Gene CNV Profiles -1.0 -1.3592 GTEX-PSDG-0226-SM-33HC1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.92538 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18372 hepatoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.096279 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29977 layer 1 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90307 NCIH82 CCLE Cell Line Gene Expression Profiles -1.0 -2.13906 OSC-19 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-UPJH-0326-SM-3GADU GTEx Tissue Sample Gene Expression Profiles 1.0 1.0949 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17771 H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1187 COSMIC Cell Line Gene CNV Profiles 1.0 2.2355 Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.791 Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NJ-01A-22R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE123638,GSE123639_3_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures -1.0 null PPP1R14A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14773 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null foxa1_21151129_mcfdash7_lof_human_gpl10558_gse25315 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.116908 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.290994 GTEX-S4UY-0126-SM-3K2BB GTEx Tissue Sample Gene Expression Profiles 1.0 1.78298 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.59763 GSE106130_0_v_1_grhl2_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.92726 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX Rummagene Transcription Factor Associations 2026 1.0 null TET1 ChEA Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-94-8490-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.93005 PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6029 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3279 Reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.042 MEF2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21937 GTEX-S3XE-0826-SM-4AD4U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0665 EP300_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.374618 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHAGO-K-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QMR6-0011-R7A-SM-32PKL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31676 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCMCRM2 DepMap CRISPR Gene Dependency 1.0 2.27334 GFER Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PWO3-0011-R2A-SM-2S1OX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62109 GTEX-X4XY-0008-SM-46MVL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16422 GTEX-P4PQ-0726-SM-3NMCR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.886711 LP1 DepMap CRISPR Gene Dependency 1.0 5.22679 GTEX-TML8-2026-SM-32QOP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963307 HDAC2 ENCODE Transcription Factor Targets 1.0 null GSE147366_1_v_2_med13_human RummaGEO Gene Perturbation Signatures -1.0 null STOM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08361 zonal layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08168 collicular (rostral) midbrain tectum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04146 Pectoral fin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.658 layer 6a of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02237 GTEX-WYVS-1626-SM-3NM9R GTEx Tissue Sample Gene Expression Profiles 1.0 1.29846 Perturb_17198_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-T2IS-0126-SM-4DM6O GTEx Tissue Sample Gene Expression Profiles 1.0 1.40657 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062001 identical protein binding GO Molecular Function Annotations 2015 1.0 null lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17703 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2287 RTCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17209 mantle zone of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08892 hsa-miR-583 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 SVBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4246 GTEX-RTLS-0426-SM-2TF5K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.80188 central part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02312