association	dataset	threshold value	standardized value
BRD-K16681480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43358
Isocorydine_NCI-H2030	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0250706
MJ	DepMap CRISPR Gene Dependency	1.0	2.04487
TMEM184B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20226
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.36981
GAMG	DepMap CRISPR Gene Dependency	1.0	2.63762
BRD-K25039453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02576
GSE200320_3_v_2_mfge8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146865,GSE146866_1_v_0_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K87875370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35169
BRD-K37253987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33555
A549_Flavopiridol HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126715
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144346_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	1.0	null
(S)-Crizotinib_Hs 766T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0110999
Neuroticism	DisGeNET Gene-Disease Associations	1.0	null
GSE190555,GSE190557_2_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TNFRSF25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00441431
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K89805365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04096
Volasertib_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0146668
BRD-K71501826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07479
BRD-K53774433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.87113
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sinomenine_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0143369
Short Nose	DisGeNET Gene-Phenotype Associations	1.0	null
Pharyngeal arch cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
BRD-K88328128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21003
C11orf71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14402
BRD-K63468420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22609
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
YD38	DepMap CRISPR Gene Dependency	1.0	2.79521
Leydig cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32565
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.844
BRD-A68913459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.51034
BRD-K93836438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6435
BRD-K00773626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15183
HBQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73068
BRD-K83667863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06589
BRD-K87942399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21844
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
G30769VJ	GlyGen Glycosylated Proteins	1.0	null
BRD-K05400180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59015
BRD-K94205659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68002
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Proteoglycan biosynthesis	WikiPathways Pathways 2024	1.0	null
CMLT1	DepMap CRISPR Gene Dependency	1.0	4.32894
GSE236815_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MM485	DepMap CRISPR Gene Dependency	1.0	3.06079
BRD-K66623602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04301
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3623
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.448
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16694974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16324
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37099
Cytarabine_NCI-H2030	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0316442
8719_TBC1D3_ENST00000537432.1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.534112
BRD-K72792753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22733
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.03958
BRD-K52190624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46384
BRD-K09376136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87563
BRD-K73337367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23903
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17856
BRD-K93051667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01902
CRCGN009_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05817
GSE65617_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02195
BRD-K87516578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43621
BRD-K32043305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01587
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tozasertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149419
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle lumen	GO Cellular Component Annotations 2023	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K61590534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87186
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-stat1-hela_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6606599-41598_2019_45777_MOESM14_ESM.xlsx-SAVA_DE_genes_promoter_DMRs-Unnamed_29_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
short scapula	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K17421394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35685
GTEx Nerve 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-7.49159
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K29458940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14349
BRD-K66479240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16763
BRD-K86155400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40684
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Relugolix_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0206289
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31489
CRCGN015_MCF10A.TP53.M_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84584
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03549
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29673910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2544
GSE221742,GSE221743_1_v_2_sipa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPATC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00571918
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-AHR-Unnamed_0_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K29571884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16548
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K21483524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37812
BRD-K91576495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07731
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154577_2_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
8157_SMC3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.674706
BRD-K19106745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4273
Tucidinostat_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0219404
GSE188382_4_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01299
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51676
Melanoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
BRD-K36134264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14072
GSE195559_8_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17399
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.046
BRD-K50400833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61339
Abemaciclib_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0205433
BRD-A30547447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11554
BRD-K09693670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4893
Mebendazole_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0153682
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2882	DepMap CRISPR Gene Dependency	1.0	2.84079
Clofarabine_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0284923
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145311_1_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Phase II - Conjugation of compounds	Reactome Pathways 2024	1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NF-kappaB p50/p65 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.037
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rifaximin_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0256543
BRD-K53491881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71352
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71016
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.6121
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14941
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Veliparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160766
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S26-Table_S26_MR_resluts_of_blood_proteins_in_AGES_project_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211177,GSE211178_9_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8919
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04408214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1051
BRD-K04251837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11133
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36709
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Benproperine (phosphate)_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0204878
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71083
HTT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60134
BRD-K42862653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19354
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.52579
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
A549_UNC0379_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139587
BRD-K07855097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51083
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00254
BRD-K05586628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40342
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03367
BRD-K32423836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1916
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HK-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
1844_CPSF6_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.1006
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K27671601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14592
Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69348766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07578
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2177
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEIS2_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
Knee Joint Valgus Deformity	DisGeNET Gene-Disease Associations	1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4B-Up_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K90762344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09073
LLC-WRC 256 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
Cleft Palate	DisGeNET Gene-Disease Associations	1.0	null
BRD-A35495382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35056
GSE62843,GSE64370_0_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K53447551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02889
GSE233566_1_v_2_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03251
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83692
BRD-K70532227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80768
GSE70935_2_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
G77582RK	GlyGen Glycosylated Proteins	1.0	null
BRD-K36763492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22831
BRD-K08941280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08483
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79732056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43642
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Levobupivacaine (hydrochloride)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0174002
GSE210667_1_v_0_rfx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75325409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69107
Golgi lumen	GO Cellular Component Annotations 2023	1.0	null
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
Endomembrane system	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.584
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
nucleotidase activity	GO Molecular Function Annotations 2023	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565976
BRD-K29547381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01524
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171344
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.792912
BRD-K84593875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05649
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20514
GSE140322_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48864953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46431
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal cartilage development	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K02061146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23226
Macitentan_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0236864
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
KP1N	DepMap CRISPR Gene Dependency	1.0	3.65715
BRD-K71007902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55475
increased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7563
K562_BMS-536924_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018641
BRD-K70652938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73911
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2592
BRD-K68247783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45163
BRD-K64268886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31854
BRD-K12709183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3328
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02173
Stolon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CISD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1081
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.796
PMC9950457-mmc3.xlsx-AP2A_binding_sites_GRHL2_KO-LRRC32_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6814198-NIHMS1538462-supplement-2.xlsx-Transitory_415genes-SNAI2_SNAI2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K55518911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73859
42MGBA	DepMap CRISPR Gene Dependency	1.0	3.31542
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.764435
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	150.682
trans-Golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9490101-mmc3.xlsx-Sheet1-Supplementary_Table_3_Differentially_expressed_genes_in_CASC11_KD_MHCC-97H_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09227140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26232
GSE86507,GSE86509_4_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24369860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63114
A549_Quercetin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169979
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19893
trans-Golgi network	GO Cellular Component Annotations 2023	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Phenylephrine (hydrochloride)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0130829
Dapagliflozin ((2S)-1,2-propanediol, hydrate)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0279666
BRD-K45013233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99787
BRD-K48782834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42806
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03432
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07281036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48155
BRD-K59194147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23025
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206784_3_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12749985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1071
GSE135514_8_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dihydroartemisinin_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0193524
PMC6606599-41598_2019_45777_MOESM14_ESM.xlsx-SAVA_DE_genes_promoter_DMRs-Unnamed_22_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02363
BRD-K01250897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44295
JM1	DepMap CRISPR Gene Dependency	1.0	2.47654
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K47456612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41965
A549_Carmofur_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177169
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55357
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71165
4273_KARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.525336
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9943
LY-2584702 (tosylate salt)_A549	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00383984
GSE173873_10_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200320_1_v_0_mfge8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adenine_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0173685
BRD-K55164454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39643
methionine-importing ABC transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
Furosemide_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0108694
PMC11459707-12890_2024_3289_MOESM1_ESM.xlsx-TableS3_MR_results-Supplementary_Table3_The_causal_effect_of_proteins_on_IPF_risk_from_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44520987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76525
BRD-K87412446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14416
BRD-K10241968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7828
DIDO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00806982
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.555074
BRD-K93519076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19846
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18343
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42733
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0415
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	3.06685
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sternum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36544
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA1_201_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73027631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15344
Peritoneal Dissemination	DisGeNET Gene-Disease Associations	1.0	null
Gefitinib_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00950415
GSE153923_1_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K00505499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78927
GSE154577_7_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K06576075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73796
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47620421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19295
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16612
BRD-K38853406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95705
BRD-K69668687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46795
BRD-K31783246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67288
DCTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77771
Exophthalmos	DisGeNET Gene-Disease Associations	1.0	null
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26723
BRD-A99687212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20767
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Isocorydine_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0330978
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Milk allergy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K01817716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33347
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A39900448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92974
BRD-K62147342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63538
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K62418398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37683
hTERT-HPNE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.05136
GSE211177,GSE211178_0_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S25-Table_S25_MR_resluts_of_blood_proteins_in_AGES_project_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Fingolimod (hydrochloride)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.026473
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Table_S1_Lists_of_translational_targets_of_MYC_in_MYC_ON_vs_MYC_OFF_P493_cells_and_their_5_UTR_sequences_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K08141534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13135
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hexylresorcinol_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0220151
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-Suppl_Table_6_DEG-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-RUNX1_mod_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
round head	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K12067186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21535
BRD-K93785828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14232
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34815008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26799
PMC9218734-Supplementary_Data3.xlsx-KRIEG-KRIEG_HYPOXIA_NOT_VIA_KDM3A_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_TMP195_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014221
BRD-K39962926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63262
3503_GPN2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.655425
Microstomia	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.4398
BRD-K90155857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09823
BRD-K28811650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58281
PMC11214527-mmc5.xlsx-ADNP-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K48255349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06509
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K39435284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28929
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_35_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7519331-pnas.1921408117.sd11.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94657740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94705
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_3_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00394
Benztropine (mesylate)_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0217156
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1228
short tibia	MGI Mouse Phenotype Associations 2023	1.0	null
AZD-7648_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0143731
intracellular organelle lumen	GO Cellular Component Annotations 2025	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cabozantinib (S-malate)_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0257362
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0936
Coronal Craniosynostosis	DisGeNET Gene-Disease Associations	1.0	null
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
trans-Golgi network membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A71001587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36874
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K54247106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0392
CRCGN013_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25347
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06119
GSE182854_2_v_0_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232944_1_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88478877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17781
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46995
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67284043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50936
BRD-K67027685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58419
Micrognathism	DisGeNET Gene-Disease Associations	1.0	null
AGMAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35293
BRD-K02565327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18114
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11871
BRD-K44975377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45616
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Methylprednisolone succinate_A498	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0125677
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18119
Aliskiren_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0173628
BRD-K32522318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1632
BRD-A57536034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35327
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.0578
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59412
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12823
GSE225647_1_v_3_srsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52319351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33694
MCF7_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.022354
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Homoharringtonine_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0135364
perinatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K35341092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0893
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Apalutamide_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0225813
RAB5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06114
BRD-K36003376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6086
BRD-K62188824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94519
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5667
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.751
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02788568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84246
BRD-K80897487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59568
BRD-K42475945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82181
BRD-K30992744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01569
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03399
WM1799	DepMap CRISPR Gene Dependency	1.0	2.73126
BRD-K86623758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61567
MFE319_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	13.8045
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91866516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71431
Elagolix sodium_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00932045
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pulmonary artery smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
Omeprazole (sodium)_LoVo	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.009753
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_7_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70305
GSE211215_1_v_0_akr1b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53158
BRD-K96075847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42511
MM253	DepMap CRISPR Gene Dependency	1.0	4.57466
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-11.4767
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00277
8557_STX5_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.00776
HCT15	DepMap CRISPR Gene Dependency	1.0	4.9008
L-Thyroxine (sodium salt pentahydrate)_HCT15	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0140346
BRD-K05253426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02492
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7519331-pnas.1921408117.sd18.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.472
PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Unnamed_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140881
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1156
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE132386_1_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7911
BRD-K75779523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19402
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
short sternum	MGI Mouse Phenotype Associations 2023	1.0	null
ADPGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14439
BRD-A77181042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07175
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE249544,GSE249637_9_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Phenytoin (sodium)_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0230434
GSE140322_3_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31829
Gallic acid (hydrate)_SK-MEL-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0120472
BRD-K56699877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44631
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67830713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01864
GSE154577_6_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38899
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K41793515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15871
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
synapse-associated extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
A549_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162166
short ulna	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K05118861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54177
BRD-K09871160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04953
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6376
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94439911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02096
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
gm03123	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
BRD-K34005205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10944
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_2_TBRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
Carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7409
BRD-K66408914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98766
BI-78D3_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0171773
Desbuquois Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Naproxen_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0335308
Long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.511
BRD-K38493972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09263
GSE225982_1_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K78656517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05543
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185163_5_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71216961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27847
BRD-K56531121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05467
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.084
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K99038919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2723
BRD-K08647020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23818
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05934
GSE158834_10_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216757_0_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A13082766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06968
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46588240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65301
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COL27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16277
BRD-K82662168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96916
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02746
BRD-K12240312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17866
GSE178532_1_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.368
BRD-K65178566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17139
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Plicamycin_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0151535
BRD-A73635700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46903
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K34232791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1535
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Response to selective serotonin reuptake inhibitors and depression	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
BRD-K88974575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33296
BRD-K23664196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56531
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180067
RCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75252
BRD-K53752646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13315
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53146097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20207
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4029819-pone.0098069.s006.xlsx-Sheet1-Table_S5_FSS_analysis_of_FOXA1_high_versus_FOXA1_low_cases_in_metastases_p-value_0_01_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56895780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38257
BRD-K36847650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23733
Naproxen_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0179105
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04913
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Epiphyseal growth plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5951
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23152
BRD-A37523642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66855
496100598_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61612
BRD-K52876244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61193
BRD-K91011325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49061
BRD-K66993610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00875
Glasdegib_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.027802
A549_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150439
BRD-K50278697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16086
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00151
Hexylresorcinol_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0293992
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-E20_624_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85232515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12915
BRD-K21771537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02956
BRD-K21327356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29276
G69108CV	GlyGen Glycosylated Proteins	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	3.20447
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73387470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68186
Pentagastrin_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0175114
PMC12885693-medi-105-e47525-s001.xls-Sheet2-eQTL_MR_results_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ribociclib_NCI-H2030	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0208766
GSE134375_3_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
perinatal lethality	MGI Mouse Phenotype Associations 2023	1.0	null
Naproxen_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0223383
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K48408404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40245
GSE102870_7_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32079609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84026
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.2681
BRD-K01030150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68336
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18409585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16496
Naproxen_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0274141
BRD-K57045425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00502
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Alisertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142528
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14534
BRD-K39715006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.01402
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56357490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39882
BRD-A39407481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59299
BRD-K39978929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50356
BRD-K40939137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68948
BRD-K84310612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07082
S-Adenosyl-L-methionine (disulfate tosylate)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0181561
BRD-K45042519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66958
PMC5806898-pbio.2004411.s003.xlsx-MR_plot_data-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
496100595_PCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.54448
BRD-K12824862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07611
BRD-K21449711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0711
Sulfate adenylyltransferase complex (ATP)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.217
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41310621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35226
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74300740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12363
BRD-K32319151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44106
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K24396733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00405
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149075_6_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.104
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8056
A549_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012492
Golgi lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1168
BRD-K83895653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0027
Raltitrexed_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0173283
CRCGN013_HEPG2_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21855
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0292
Golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.584
PMC11250262-41588_2024_1798_MOESM4_ESM.xlsx-ST18_665_top_menarche_genes-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3907
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
6096_PAX9_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.50188
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49294
GSE186460_0_v_2_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Tubastatin A HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150988
BRD-K56309946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11105
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08995
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.113
BRD-K51228600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12603
BRD-K68270916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5626
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K21610715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0006
BRD-K82509605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53651
BRD-K38706080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28904
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53540914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55296
BRD-A20182314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67946
Erlotinib_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0189385
A549_Abexinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01207
8-Hydroxyquinoline_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00918196
BRD-K81999794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14275
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3919
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5938
BRD-K32988853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49352
Tolcapone_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0258436
PMC4777381-pone.0150624.s006.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
MYO3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00397391
7057_RAC3_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.30216
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8052288-mmc4.xlsx-PAF-DREAM-Lung_Poor_Survival-Unnamed_5_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S16_LF_C2_8h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54007898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36374
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.53955
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71357636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91682
GALK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40986
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K79204912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59343
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26461918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10708
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A04258855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00251
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K14414396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57161
TBCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664062
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08628
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE85302_4_v_1_kat6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08979
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S24-Table_S24_MR_resluts_of_blood_proteins_in_AGES_project_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88504000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82476
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	148.905
Phosphatidylinositol signaling system	KEGG Pathways 2026	1.0	null
BRD-K58005972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04472
PMC11109217-41420_2024_2017_MOESM3_ESM.xlsx-Fig_4H_TAF2-bound_genes-Tag_dentsity_of_TBP_ChIP-seq_signal_for_TAF2-bound_genes_in_Fig_4H_TBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K84939696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38342
A549_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145521
BRD-K34851865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19649
PMC11110418-12864_2024_10412_MOESM1_ESM.xlsx-S_Table_2-Supplementary_Table_2_Detailes_of_the_instrumental_variables_of_plasma_proteins_used_in_discovery_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5509726__F3	PFOCR Pathway Figure Associations 2023	1.0	null
U2904	DepMap CRISPR Gene Dependency	1.0	6.1032
BRD-A11154023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38066
GSE227592_5_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K19457629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30209
Pentamidine (isethionate)_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0319026
Bortezomib_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00924693
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-128907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58411
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210373_0_v_1_cntnap4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A27056524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85946
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D1_1084_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11659389-42003_2024_7403_MOESM4_ESM.xlsx-4-Supplementary_Table_4_Result_of_the_primary_proteome-wide_MR_of_SCC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52428486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73493
BRD-K00048155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1337
EPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1149
BRD-K21119095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27827
BRD-K12836153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37094
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36538
PMC6853299-pbio.3000476.s011.xlsx-Fig_4A-HVC_612_gene_expression_ratio_in_ZF_and_OF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45845217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73096
BRD-K70566686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14038
GSE158320,GSE183351_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K62909525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16342
chrysophanic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15716
GSE124375_13_v_12_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73528610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34498
BRD-K19381111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12738
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A52893269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44233
BRD-K70735803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66979
BRD-K88313926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5747
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
8271_SON_P1	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.20183
BRD-K07602825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42767
PMC12439337-thnov15p9091s1.pdf-95-ENSG00000126804_ZBTB1	Rummagene Transcription Factor Associations 2026	1.0	null
2339_DPCD_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.565711
Methylthiouracil_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0106294
High Forehead	DisGeNET Gene-Phenotype Associations	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal skeleton morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_12_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07679
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87634
skeletal system development	GO Biological Process Annotations 2025	1.0	null
Pimitespib_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0145734
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5965
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
3050_FDPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.504891
Belzutifan_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.014442
FBXO33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
CRCGN016_MCF10A.TP53.M_24H:C16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66012
A549_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0094902
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0001
BRD-K88128293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97307
BRD-K22720379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10033
GSE126504_0_v_1_hpse_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K90863245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23708
PMC11383936-41598_2024_71738_MOESM6_ESM.xlsx-DEPs_LMS_vs_LMS_-_vs_HC-Unnamed_4_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64469421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74138
GSE254517_1_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate	GTEx Tissue Gene Expression Profiles 2023	1.0	3.01069
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.008
disorganized long bone epiphyseal plate	MGI Mouse Phenotype Associations 2023	1.0	null
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
axial skeleton hypoplasia	MGI Mouse Phenotype Associations 2023	1.0	null
GSE224969,GSE224971_3_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59970200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15804
BRD-K87803080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81171
GSE99687_3_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Belinostat_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0198595
Macitentan_SNU-423	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00605376
BRD-A77907596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16612
CRCGN015_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0742
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	14.4436
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80306
GSE114992,GSE114993_4_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Clobetasol propionate_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.022669
PMC11659389-42003_2024_7403_MOESM4_ESM.xlsx-5-Supplementary_Table_5_Result_and_IV_SNPs_of_the_primary_proteome-wide_MR_of_MM_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34252131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10816
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43136464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53421
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nimesulide_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0213394
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6373
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180525,GSE180528_2_v_3_tbx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Lipoic acid_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0243139
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36462
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30314
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
Phosphopantothenoylcysteine decarboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
Erythromycin_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0311239
BRD-K26748243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55862
BRD-K04980212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69977
Malotilate_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0293613
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55722
BRD-K52423731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35682
BRD-K41063113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17873
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43989220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08167
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fluvoxamine_SW 900	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0238349
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32163
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PBXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2864
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26232524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33411
BRD-K17790291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65711
BRD-K49368687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25355
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61711624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35532
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pemigatinib_AsPC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0173645
GSE186483_1_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NKIRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79763
Naproxen_NCI-H2030	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0235132
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0625
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cytosolic sulfonation of small molecules	Reactome Pathways 2024	1.0	null
BRD-K74245698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99105
MPZL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00362554
GSE184884_6_v_5_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K51370144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39096
CRCGN011_HEPG2_24H:C13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7164
BRD-K73014869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37539
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	130.567
CRCGN016_MCF10A.WT.HP_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01089
BRD-K98522669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31631
GSE115542_2_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
disproportionate dwarf	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K55800245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4107
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83163
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173201_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03837143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32055
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7775
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
FOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12451
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR72	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00646785
Fluvoxamine_HCT15	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.020905
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23164928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31432
BRD-K87580376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20824
Sulfur metabolism	KEGG Pathways 2026	1.0	null
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13852343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19591
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.26753
PMC10244410-41467_2023_39054_MOESM5_ESM.xlsx-PIE-LIN28B-GeneSymbol_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Abiraterone acetate_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00749433
A549_PJ34_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164535
atelectasis	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN011_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34985
BRD-K77108738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40667
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
USP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0189
BRD-K52833964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81038
BRD-K82538319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68106
CRCGN015_MCF10A_48H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27372
PMC11103890-mmc3.xlsx-ZZZ3_interactors_ESC-2-Gene_names_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K35404627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57795
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Almonertinib (mesylate)_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0288657
BRD-A07952294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10933
Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.181
BRD-K04095185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36742
BRD-K83818372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2834
GSE254770_3_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29771129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53031
KCTD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00049
GSE184356_1_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6381
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.95729
8-Hydroxyquinoline_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.004248
BRD-K12524104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07476
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Omeprazole (sodium)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0147087
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal joint morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PMC11659389-42003_2024_7403_MOESM4_ESM.xlsx-3-Supplementary_Table_3_Results_and_IV_SNPs_of_the_primary_proteome-wide_MR_of_BCC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
LIVF001-005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25646
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K03489727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78041
A549_Baricitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143552
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3872
BRD-K98276754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34316
Epithelioid Mesothelioma, Malignant	DisGeNET Gene-Disease Associations	1.0	null
GSE248045,GSE248046_0_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Phenytoin (sodium)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0123798
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06925
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96382853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40626
BRD-K63086103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15417
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61271364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57723
BRD-K66675422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3321
BRD-K41548770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10099
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112763,GSE112767_2_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2724
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21833
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_MC1568_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151614
EWSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02433
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49951
BRD-K53388755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46715
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18737347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21894
Tirabrutinib_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0193837
TERF2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8495
HC-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
BRD-K14470344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59354
BRD-K76904668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61418
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A15454510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20761
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10594727-13062_2023_428_MOESM14_ESM.xlsx-Sheet1-PPARD_PPARD	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183335,GSE183351_3_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7178_RBM48_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.570439
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
4371_KIAA1958_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.613693
short femur	MGI Mouse Phenotype Associations 2023	1.0	null
G83229XP	GlyGen Glycosylated Proteins	1.0	null
BRD-K10871135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00415
BRD-K89142472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19853
GSE211128_9_v_8_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CORL88_LUNG	CCLE Cell Line Proteomics	1.0	4.3451
ERK5-IN-2_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0193492
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE211177,GSE211178_8_v_10_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22189231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0198
BRD-K94062017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03281
CRCGN012_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85212
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PNT2-C2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.624675
Sternal cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
BRD-K85722200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31295
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
short radius	MGI Mouse Phenotype Associations 2023	1.0	null
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12494973-41467_2025_63880_MOESM1_ESM.pdf-93-NEUROG3_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11677
BRD-K81465091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15367
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K36095954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0662
BRD-K04181823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0214
GSE86021_0_v_1_crenolanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4c-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
short ribs	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K15940717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40135
BRD-K17136501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39432
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8208823-mmc2.xlsx-CDX2-KO_epithelial_DEG-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
BECKER	DepMap CRISPR Gene Dependency	1.0	3.31751
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18559
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1156
KD	DepMap CRISPR Gene Dependency	1.0	2.19359
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K42508877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1337
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.03322
MCF7_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00779305
CRCGN011_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16405
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35235
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
BRD-K37506332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48765
CRCGN015_MCF10A_48H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.35548
PMC12749580-42003_2025_9274_MOESM5_ESM.xls-Supplementary_Data_2A-Supplementary_Table2A_Full_results_of_the_proteome-wide_MR_in_deCODE_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
496100603_PCx_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36886
BRD-K28746174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13589
GSE149075_6_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83919473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03695
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97540907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31813
cleft palate	MGI Mouse Phenotype Associations 2023	1.0	null
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14132
CRCGN013_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0105
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4448
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.772677
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
methionine-importing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.51
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6435
VCAP	DepMap CRISPR Gene Dependency	1.0	6.35647
BRD-K88590066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22672
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tofacitinib_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0142825
Prostate epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.313
BRD-K09395335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01209
GSE146074_6_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K23535862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47556
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Talc_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0240091
Perineuronal net	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
BRD-K90359063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08641
IM95_STOMACH	CCLE Cell Line Proteomics	1.0	2.30513
Pyridoxine_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0183142
BRD-K13235291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.265
phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_MCF10A_48H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39829
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10290283-biol-2022-0622-sm3.pdf-258-ZNF497_ZNF497	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129571
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9976
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
BICR16	DepMap CRISPR Gene Dependency	1.0	5.36183
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K15499806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48096
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05012
BRD-K15876355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50548
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14415
GSE87404,GSE87812_2_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
BRD-K68379391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33362
PMC11699013-12672_2024_1699_MOESM1_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_The_association_between_proteins_and_CLL_in_the_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
G57321FI	GlyGen Glycosylated Proteins	1.0	null
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1186
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16643911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23056
BRD-K52731672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05543
BRD-K00938872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74264
A549_TAK-901_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152074
BRD-K28339544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45145
t59-kidney_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.33055
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LJI308_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0225879
GSE193249_0_v_1_gpx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Cimetidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150943
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157233_2_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44955380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18845
BRD-K31852848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72466
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114992,GSE114993_4_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76263570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56125
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Ensembl_ID_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138863_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.496
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SEH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00501
Macitentan_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0163473
5928_OGFOD1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.18092
BRD-A09988375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08704
HUPT4	DepMap CRISPR Gene Dependency	1.0	5.3984
BRD-K61310138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15037
BRD-A97759891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76429
P2RY8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053392
BRD-K23857235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14437
BRD-K48029682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90059
EM2	DepMap CRISPR Gene Dependency	1.0	3.78238
PMC9675280-12950_2022_317_MOESM2_ESM.xlsx-LPS_BB-Cl_vs_LPS-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27067020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25439
A549_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152758
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60475
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nasal Bridge Wide	DisGeNET Gene-Phenotype Associations	1.0	null
short fibula	MGI Mouse Phenotype Associations 2023	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47443098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14655
BRD-K19523047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71114
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8764
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K61092554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54178
BRD-K61687409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04503
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K08982277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81762
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sonidegib_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.034047
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K58220566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50643
BRD-K14216093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08831
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67898193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97368
BRD-K42529194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19848
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K19046167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13899
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.046
BRD-K18488784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.361
TXN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00440083
BB30HNC	DepMap CRISPR Gene Dependency	1.0	11.0551
BRD-K63394284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5074
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27475
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Selinexor _SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00839433
BRD-K11010670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70012
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K08355771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62007
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D2REFED4h_641_AR-D-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27600134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35012
BRD-K02315086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10945
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67403750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15551
Ceratobranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
Minodronic acid_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0129734
Hand grip strength	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K51502220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08524
Everolimus_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0242569
K562_Resveratrol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150367
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1824
BRD-K87092114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28348
Goserelin (acetate)_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0261163
PMC10716174-41467_2023_43919_MOESM10_ESM.xlsx-top500_STAT1_ChIPseq_ENCSR000EZ-ENSEMBL_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9811745-40246_2022_449_MOESM1_ESM.xls-Sheet1-HOXA2_HOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8208823-mmc2.xlsx-CDX2-dataset-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
G47012YE	GlyGen Glycosylated Proteins	1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G43417UB	GlyGen Glycosylated Proteins	1.0	null
HCC-827 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1936
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50749
BRD-K60760423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07026
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Macitentan_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0131005
BRD-K20722478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61501
BRD-K81510336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3708
GSE85302_0_v_1_kat6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW403_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.36332
BRD-K66821167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18004
Short Metacarpal	DisGeNET Gene-Phenotype Associations	1.0	null
GMEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3251
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAFAZZIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82778
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6295
A549_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186118
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.313
BRD-K42126155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00564
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6168
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.046
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.9077
A549_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129248
abnormal respiratory system physiology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE184133,GSE184137_2_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K84802956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17891
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_up-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5130036-oncotarget-07-40690-s006.csv--AR_signature_for_GSEA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41798816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12599
BRD-K57084585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68838
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
8288_SOX2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.660683
CRCGN010_HEPG2_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2365
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41102088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29136
MCF7	DepMap CRISPR Gene Dependency	1.0	2.08678
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K78712486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41997
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89931949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87014
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
K562_Cyclocytidine HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141834
BRD-K13941175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09286
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06935
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FDX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541576
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90712
UNC93B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512497
BRD-K33064128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61296
BRD-K45091989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00733
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20288742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08034
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32949071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54306
BRD-K54332342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29991
BRD-K67813189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10443
TM9SF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00436241
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Short Toe	DisGeNET Gene-Phenotype Associations	1.0	null
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A53381587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31576
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86750448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.107
Fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
Fingolimod (hydrochloride)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00706274
BRD-K82292504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52719
BRD-K83875224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00631
BRD-K10176883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56358
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11639743-mmc2.xlsx-LIN28B-gene_name_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01108
G31544HA	GlyGen Glycosylated Proteins	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K70533557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01563
BRD-K48448518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3023
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lipoic acid_SK-MEL-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.01518
BRD-K79334072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40276
BRD-K68953461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55417
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22081
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-fig-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10027041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84261
A549_S3I-201_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143467
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131425_2_v_0_arg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12816669-41698_2025_1236_MOESM1_ESM.pdf-958-STAT4_STAT4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7589
Almonertinib (mesylate)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0480485
A172	DepMap CRISPR Gene Dependency	1.0	3.56881
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71707
PMC11485038-384_2024_4744_MOESM1_ESM.xlsx-Sheet3-Supplementary_Table3_Unique_leader_cis-pQTLs_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7857731-elife-63093-supp5.xlsx-ECMdegs-MITF-X6_vs_EVSkMel28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K91654198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07559
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K00591281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1219
trans-Golgi network membrane	GO Cellular Component Annotations 2025	1.0	null
BRD-K16754572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79146
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154577_13_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08113936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82994
BRD-K35058762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36991
A549_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166482
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perisynaptic extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
PDLIM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59669
BRD-A51381734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22192
NMuMg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17323
ASPC1	DepMap CRISPR Gene Dependency	1.0	4.92223
GSE70883,GSE71179_0_v_1_pbx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.321
BRD-K74482064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51355
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00296
RNPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22172
RPP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38107
BRD-K20185935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70614
BRD-K98856654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56966
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5454
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.542113
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09268
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11214527-mmc5.xlsx-TP53-gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95571
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03825
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chondrodysplasia	DisGeNET Gene-Disease Associations	1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	3.22018
PMC4521181-oncsis201520x8.pdf-41-ZNF654_ZNF654	Rummagene Transcription Factor Associations 2026	1.0	null
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11974
BRD-K85532298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30575
BRD-K22173206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26533
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K40088786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45772
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4816
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	1.60374
PMC11630641-mmc8.xlsx-Human_1000cell_NOT_identified-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85392247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14789
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE131649_4_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_ABT-737_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182783
BRD-K29366596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07447
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K31521981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10602
Selinexor _HCT15	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.014688
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.02781
GSE148494,GSE182513_1_v_0_hoxd13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K57323824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17836
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMGN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03319
iodoquinol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6336
BRD-K26631178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20759
BRD-K84745303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22443
BRD-K28596340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36268
GIMEN	DepMap CRISPR Gene Dependency	1.0	2.11325
BRD-K60850201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06154
Intrinsic component of external side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.217
Doxorubicin (hydrochloride)_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.021959
Pimitespib_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0250479
BRD-K43224838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.90157
GSE149035_1_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Erdafitinib _J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0145884
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Goserelin (acetate)_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0273964
NNAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26313
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_IOX2_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127844
Cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
short limbs	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K51743001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06123
BRD-K62707745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3823
BAX complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
GSE161846,GSE161849_1_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.974
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41873
Ponatinib_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0249649
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K80240487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29376
BTS	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10718
GSE134375_4_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
respiratory distress	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K45010872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81905
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.748
GSE242333_0_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10834
BRD-K60460300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17974
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09583
BRD-K43126701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91713
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K71742655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2878
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7106
CRCGN015_MCF10A.WT.HP_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34023
HSD17B12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35277
LPS6	DepMap CRISPR Gene Dependency	1.0	4.97076
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.720451
GSE201042_2_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63145472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06604
STX1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512436
BRD-K52104866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01219
GSE203329_0_v_3_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nuclear body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
decreased birth body size	MGI Mouse Phenotype Associations 2023	1.0	null
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K14327064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07276
RBBP6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0102864
Pentamidine (isethionate)_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.01922
Golgi stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.927
CRCGN012_HEPG2_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60289
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39752756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38288
GSE205963_0_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN013_HEPG2_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36866
BRD-K82397896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04051
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PNT-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0307
BRD-K79635719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72379
BRD-K95656102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04321
PMC11459707-12890_2024_3289_MOESM1_ESM.xlsx-Table_S8_MR_results-Supplementary_Table8_The_causal_effect_of_proteins_on_IPF_risk_from_UK_Biobank_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Arbutin_NCI-H2030	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0192068
BRD-K04928505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35503
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
3'-nucleotidase activity	GO Molecular Function Annotations 2025	1.0	null
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95068765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69285
BRD-K23617623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12071
BRD-K45677596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47198
BRD-K79684522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6737
abnormal axial skeleton morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K17893805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55276
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LB-100_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0142276
6794_PRPF38A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.524396
Alpelisib_NCI-H2030	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0213297
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92679
A549_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151238
GSE206870,GSE206872_4_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2043
PMC10703676-41588_2023_1569_MOESM4_ESM.xlsx-ST18-Unnamed_2_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K55612106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92957
BRD-K49755501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09513
PMC12486367-Supplementary_Data2.pdf-390-ZNF512_ZNF512	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40126748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70064
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Heparanase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
PMC11518751-Table1.xlsx-Table_S1_IV_for_MR-exposure_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79777
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Isocorydine_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0184518
Pimitespib_SW 900	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0110381
BRD-K02204058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49798
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_0_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90901488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08117
GSE218814_1_v_0_suv39h1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38403252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57868
PMC5390115-mmc7.xlsx-DE_Lists-H1-ECs_Experiment_2_H1-EC2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63858518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0678
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Altretamine_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0276948
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35505
BRD-K55392659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28306
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39607
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K35671498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13605
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CHPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0618
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChaGo-K-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAPPC6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28104
PYGL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00375081
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K98145661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41662
Catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
GSE216043_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0337
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
butylated-hydroxytoluene	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79889
BRD-K55815187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23846
Doxorubicin (hydrochloride)_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0125191
DU4475	DepMap CRISPR Gene Dependency	1.0	5.76541
Malotilate_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0300081
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35934
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.8897
BRD-K84790105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20318
GSE156923_0_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79459
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26423054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10163
phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fedratinib (hydrochloride hydrate)_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0253467
Vilanterol_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0155892
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
G83951ZY	GlyGen Glycosylated Proteins	1.0	null
9521_UBE2V2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.716338
Pimozide_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0202525
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8141
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.52895
GSE163052,GSE163198_4_v_7_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77797840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27001
MAPK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00466198
Squamous Cell Carcinoma Of Esophagus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K16207265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67964
Fingolimod (hydrochloride)_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0194639
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15282144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88051
CRCGN015_MCF10A_48H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75876
BRD-K86914375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02539
5557_NDUFB5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.648358
BRD-K11566857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43758
BRD-A95683194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79154
BRD-K60837711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53913
BRD-K56658444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41349
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.848767
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-PBX3-Unnamed_6_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_5_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8752721-42003_2021_2991_MOESM4_ESM.xlsx-Fig3_E2F2-gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11079244-Data_Sheet_2.XLSX-Supplementary_Table_2-Supplementary_Table_2_Genetic_instruments_of_plasma_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94037108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62706
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K12624449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14462
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1727
BRD-K62351887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63185
GSE154577_6_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletal system development	GO Biological Process Annotations 2023	1.0	null
BRD-K91779437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09142
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7823
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K46701848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18462
3809_HLA-C_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.520803
BRD-K14375485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3539
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29369
BRD-K08476323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3687
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K75576005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20256
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Golgi apparatus subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6922
BRD-K45394633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40694
BRD-K09977699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04446
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8162070-SC-011-D0SC04199H-s006.xlsx-SNA-Protein_Name_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20024170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10855
PMC11252802-pnas.2322203121.sd15.xlsx-Sheet1-TRP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4777381-pone.0150624.s007.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73540839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62235
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
G45883VE	GlyGen Glycosylated Proteins	1.0	null
BRD-K19691332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83074
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67406305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86054
BRD-K27265817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77814
BRD-K36314834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06875
A549_Tubastatin A HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0220758
BRD-K37049577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2165
BRD-K47821225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9251
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Regorafenib_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0226163
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Homoharringtonine_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0178723
BRD-K67522096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00022
BRD-K61621331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0883
BRD-K00667983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49772
BRD-K15400067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37138
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Clobetasol propionate_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0238481
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.084
Gefitinib_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0177512
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94598
BRD-K15675930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78319
BRD-K65823297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37236
BRD-K53088255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22353
BRD-K86716312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81011
CRCGN015_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.88721
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56113
shortened head	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K71778797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31567
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
Regorafenib_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0280635
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.407
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44946060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15242
BRD-K35668999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55167
GSE195503_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4453
GSE104022_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K66324291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2278
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2014
Vilanterol_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0174239
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1644
Rough endoplasmic reticulum lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6744
BRD-K35088248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03406
BRD-K49159670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43257
AFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80874
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K53971345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56167
BRD-K23461342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29934
GSE192689_0_v_2_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2553
BRD-K13970506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3965
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Golgi cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
A549_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149393
Idarubicin (hydrochloride)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0284399
BRD-A86415025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19047
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135514_8_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K62888534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23912
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K99903568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07419
short humerus	MGI Mouse Phenotype Associations 2023	1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-FXR-Unnamed_0_NR1H4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11985
Cytarabine_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0290017
A549_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128041
L-Thyroxine (sodium salt pentahydrate)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0237543
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A05456882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.316
BRD-K74506898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54273
BRD-K54317642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07455
Megestrol_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0292805
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K20142115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41318
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36423
BRD-K67337799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21423
BRD-K20329507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6096
A549_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182995
PMC11955568-41467_2025_57429_MOESM9_ESM.xlsx-Data_S7-JUN_OIS_Martinez2020_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K90103008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24967
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
3'-nucleotidase activity	GO Molecular Function Annotations 2023	1.0	null
HT1197	DepMap CRISPR Gene Dependency	1.0	4.42423
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S22-Table_S22_MR_resluts_of_blood_proteins_in_AGES_project_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-210-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
Cysteamine (hydrochloride)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0339461
PMC11383936-41598_2024_71738_MOESM6_ESM.xlsx-DEPs_LMS_-_vs_HC-Unnamed_4_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Tazarotene_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0325059
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.601313
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6089552-oncotarget-09-31018-s004.xlsx-compound_targets_chip_rnaseq-Chip-seq_derived_EWS-FLI1_targets_Bilke_et_al_2013_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL-AF4_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189859,GSE189861_1_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Short Foot	DisGeNET Gene-Phenotype Associations	1.0	null
Perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.093
PPIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36765
BRD-K59938516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17513
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98288
GSE114992,GSE114993_9_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55891520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63092
BRD-K66145389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32015
GSE62843,GSE64371_2_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87418665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43195
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.3636
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4728380-ncomms10153-s8.xlsx-MYC_binding_intensity_ALL-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20091931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26265
BRD-K01754917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25806
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K02688026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01989
c2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
BRD-K32913479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41148
Merkel Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K95501793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15454
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K63856509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05718
BRD-K10925833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5064
BRD-K33260002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46969
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K81916372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26165
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14264
BRD-K60782883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41987
ADAM17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552612
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO684	DepMap CRISPR Gene Dependency	1.0	2.43603
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
(R)-Verapamil (hydrochloride)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.024496
PMC9675280-12950_2022_317_MOESM2_ESM.xlsx-LPS_vs_control-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G81198YO	GlyGen Glycosylated Proteins	1.0	null
FTSJ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.004224
CRCGN012_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04746
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Rad51B-Rad51C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.2
BRD-K28465224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26713
BRD-K47841020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84229
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00444
BRD-K51515697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0517
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-Embryo-Hatchling_1272_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67597437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11268
BRD-K51050934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70468
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08359
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	1.96695
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K43186783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41038
BRD-K62650632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15846
BRD-K56857396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36859
Lopinavir_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0185139
DPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16513
Larotrectinib sulfate_A498	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.024091
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9728
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14425
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.522602
GSE242083,GSE242098_3_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
G90093AU	GlyGen Glycosylated Proteins	1.0	null
BRD-K39705203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3133
GSE210885_2_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100467_FWM_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03218
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16295
8520_STK32C_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.552422
MCF7_Cimetidine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142609
BRD-A57353172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85199
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.351
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14905
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RPP40	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536793
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11383936-41598_2024_71738_MOESM6_ESM.xlsx-DEPs_LMS_vs_HC-Unnamed_4_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68347834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7412
GSE131660_1_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tubulin inhibitor 6_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0174965
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48833
A549_Tucidinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126848
BRD-K91917132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42217
BRD-K77782946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53954
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60267900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23824
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132286
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41453
BRD-K52341452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50681
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K16705729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20149
BRD-K44371786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15273
PJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30598
Metabolism	Reactome Pathways 2024	1.0	null
PMC3853418-1756-8935-6-34-S2.pdf-3-ZSCAN12_ZSCAN12	Rummagene Transcription Factor Associations 2026	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8683
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_18_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SBI-0640756_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0195152
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pravastatin (sodium)_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.026539
GSE154577_2_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75983763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16294
BRD-K17753765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26452
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.07525
KML1	DepMap CRISPR Gene Dependency	1.0	2.0617
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20590138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95912
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hematopoietic stem cell_Bone marrow_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE167404_1_v_0_lama4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCHR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636333
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K09308989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1721
GSE183101_0_v_1_hvcn1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nimesulide_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0210094
BRD-K89333198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73584
BRD-K74329400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25192
cleft secondary palate	MGI Mouse Phenotype Associations 2023	1.0	null
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LY6E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0897
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.975
BRD-K61555339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48281
SBI-0640756_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0241672
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleotidase activity	GO Molecular Function Annotations 2025	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K30173420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15814
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.547787
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7291
CRCGN015_MCF10A_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25759
Gefitinib_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0186128
BRD-K20530300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62444
Chlorhexidine (diacetate)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0253431
K562_Quercetin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156138
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07453
BRD-K31300534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12006
BRD-K47510632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57258
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Peretinoin_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0141156
DTP3_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0156461
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47084
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04901
MARVELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29381
BRD-K40228218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93552
LB-100_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0210732
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
496100583_PCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18023
CRCGN013_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94562
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23703
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
c91pl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
BRD-K34282646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23361
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15553
GSE211963_0_v_3_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06981
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K59239976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30037
Sulfisoxazole_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0305373
BRD-K19573822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41201
Pt-K2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03723
Phenylephrine (hydrochloride)_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0151757
BRD-K97223487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20535
BRD-K67531128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91548
Drospirenone_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0205786
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0067
BRD-K19474742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22151
OVMANA	DepMap CRISPR Gene Dependency	1.0	2.01526
GSE249544,GSE249637_9_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Symbol_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50689779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21971
BRD-K47160864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68343
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K90526956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15446
496100602_TCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4713
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03254663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03349
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Belzutifan_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0300253
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06186
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08013
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01105
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71407
NHERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16177
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02685
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
short snout	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71737
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
IM95	DepMap CRISPR Gene Dependency	1.0	2.14497
Golgi lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.032
Indacaterol (maleate)_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0305587
BRD-K15426523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84231
BRD-K67783817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41114
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S23-Table_S23_MR_resluts_of_blood_proteins_in_AGES_project_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Darinaparsin_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0177326
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18753
Flat Face	DisGeNET Gene-Phenotype Associations	1.0	null
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8175
Alcohol dependence	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
BRD-K78400597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47139
BRD-K73769678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0319
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2071
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6965
A549_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120439
SLC29A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599547
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02305
AZD2858_HCT15	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0163009
BRD-K44224150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33626
BRD-K16976282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39379
GSE146253_0_v_5_stat4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
3767_HIST1H2BK_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.580882
BRD-K05786443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04124
3',5'-nucleotide bisphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Talc_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0178181
BRD-K04722226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42284
Catel Manzke Syndrome	DisGeNET Gene-Disease Associations	1.0	null
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7744
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84788922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07555
PMC11839199-CPR-58-e13746-s001.docx-4-OSR2_OSR2	Rummagene Transcription Factor Associations 2026	1.0	null
Chondrodysplasia	ClinVar Gene-Phenotype Associations 2025	1.0	null
Pasireotide (acetate)_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0235546
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2061
Lucanthone_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0301557
BRD-K35727000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17495
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20896
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Regorafenib_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0230461
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53902
BRD-K85951787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39703
BRD-K33863933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23995
A549_Lenalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203009
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K17063694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00892
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC10716174-41467_2023_43919_MOESM10_ESM.xlsx-top500_STAT1_ChIPseq_ENCSR000EZ-SYMBOL_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35963610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60377
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125625
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22086
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	2.24126
GSE135514_2_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11166884-mmc4.xlsx-Table_S3-Table_S3_proinflammatory-EC2_comparison_between_WT_and_TG_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97421379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23125
A549_Celecoxib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153569
Biological oxidations	Reactome Pathways 2024	1.0	null
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7857731-elife-63093-supp5.xlsx-ECMdegs-MITF-X6_vs_EVSkMel28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46970272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06318
G91473PK	GlyGen Glycosylated Proteins	1.0	null
BRD-K63401627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05285
Golgi lumen	GO Cellular Component Annotations 2025	1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF224	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52499
G64527OM	GlyGen Glycosylated Proteins	1.0	null
URB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00661672
t59-kidney_female_2w	MoTrPAC Rat Endurance Exercise Training	-1.0	-1.66142
GSE236497,GSE236500_1_v_0_pemrametostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K89476396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19468
MM160113	DepMap CRISPR Gene Dependency	1.0	4.31147
Celecoxib_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0111346
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.89506
GSE221955_3_v_2_igfbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74317118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29948
SW1990	DepMap CRISPR Gene Dependency	1.0	4.33975
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.084
Blood protein levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.3699
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trans-Golgi network membrane	GO Cellular Component Annotations 2023	1.0	null
BRD-K46699670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3064
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NVP-BHG712_NCI-H2030	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0131214
BRD-A89237309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07655
GSE209973_1_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1119
BRD-K12011077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28704
BRD-K87779720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14081
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bimatoprost_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0229995
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_10_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trans-Golgi network	GO Cellular Component Annotations 2025	1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37282009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.2687
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.567605
G41882MT	GlyGen Glycosylated Proteins	1.0	null
abnormal thoracic cage morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K96596828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2999
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
Golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K42653521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30953
3',5'-nucleotide bisphosphate phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brachydactyly	DisGeNET Gene-Disease Associations	1.0	null
PHLDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59752
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.9812
ABHD17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34297
BRD-K66278562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38492
BRD-K50216418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11046
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10771430-42003_2023_5737_MOESM3_ESM.xlsx-S4-MR-AAM-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Palmatine (chloride)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0111063
BRD-K84387578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43264
BRD-K09112411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17774
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30855
A549_JNJ-7706621_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143585
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.665
K562_Pelitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163873
A549_Sirtinol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152284
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5761
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
3871_HNRNPL_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.506521
ZNF395	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01083
abnormal knee joint morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
Branch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
A549_PJ34_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124886
BRD-K99690279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15378
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.48415
Triamcinolone_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.020415
Naproxen_NCI-H23	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0237998
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.4904
BRD-K72519622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05018
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K77518191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06975
GSE200352_10_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8289
BRD-K48459037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00715
BRD-K85456301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41927
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32879108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04627
BRD-K87465930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00945
BRD-K09166899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05188
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00165
BRD-K47980183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6928
BRD-K48213854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12811
5720_NMT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.635267
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A03997826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19237
BRD-K72050226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01
AT7519_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0138214
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13267677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82816
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68497273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96164
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11419664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8382
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
LJI308_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0130392
BRD-K31081052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02883
BRD-K02484256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08984
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null