association	dataset	threshold value	standardized value
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.391
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-429	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1923
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1332
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9173
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0797
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8626
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6418
Reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2983
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6125
znf263_19887448_helas3_lof_human_gpl6884_gse19146	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.935905
Seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.63488
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
specimens	GeneRIF Biological Term Annotations	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5691
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.625
496100314_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31026
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42995
hsa-miR-4446-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-4727-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0289
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978785
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5463
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28357
hsa-miR-657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5345
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8248
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.331
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3775
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95965
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9643
Y-linked spermatogenic failure 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.879
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.536
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.0776
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67216
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00495
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838986
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
vcy2	GeneRIF Biological Term Annotations	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4107
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ligase	GeneRIF Biological Term Annotations	1.0	null
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0876
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0112
Leydig cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
MAP1S	Pathway Commons Protein-Protein Interactions	1.0	null
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.158
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32899
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08951
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0876
hsa-miR-4455	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
Hypospadias	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
arrest	GeneRIF Biological Term Annotations	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12685
496100548_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.92017
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1688
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47205
Ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.94
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1954
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974051
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7064
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4549
hsa-miR-3187-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Oligospermia	DisGeNET Gene-Disease Associations	1.0	null
Euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.529
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.367
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.42429
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.8689
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8969
hect	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-1286	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4469
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977919
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2114
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
e3a	GeneRIF Biological Term Annotations	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00495
Gynecomastia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
Congenital bilateral absence of vas deferens	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.019
Azoospermia	DisGeNET Gene-Disease Associations	1.0	null
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6858
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2204
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.467
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9814
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7915
Complete androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35164
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67216
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2243
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0845
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1549
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3708
weakly	GeneRIF Biological Term Annotations	1.0	null
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56324
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03505
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19037
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6265
biopsy	GeneRIF Biological Term Annotations	1.0	null
Persistent Mullerian duct syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3565
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.954
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869692
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.846
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6369
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.63
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.9834
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3958
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.428
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910301
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00495
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.211
Testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5144
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.507
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05254
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8299
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5891
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7758
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.545
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.9334
Mixed gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96528
testicular	GeneRIF Biological Term Annotations	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6873
46,XX sex reversal	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.88475
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0158
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2846
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5751
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14439
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2254
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2397
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0623
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3434
Gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.808
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9654
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11772
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14439
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1979
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.4306
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974051
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.6933
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7311
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0795
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.063
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40591
Male Infertility	DisGeNET Gene-Phenotype Associations	1.0	null
spermatids	GeneRIF Biological Term Annotations	1.0	null
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4623
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03505
RXR-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839508
hsa-miR-200c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28357
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4462
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8214
BCAT-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.697
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.219
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2655
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1057
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67216
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67216
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1003
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.052
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.394
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96528
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
16455954-TableS1	GeneSigDB Published Gene Signatures	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7443
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
Testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
hsa-miR-4495	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08951
WDR5-24793694-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2942
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.942
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877317
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5508
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910301
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
hsa-miR-4279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4019
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4447
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.19
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1584
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2314
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2342
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.833
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3467
DU-145 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8279
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2883
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839508
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.497
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.588
round	GeneRIF Biological Term Annotations	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9886
ubiquitinprotein	GeneRIF Biological Term Annotations	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11772
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941787
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1718
PMC7825356-8844261.f3.docx-107-TGIF2LY_TGIF2LY	Rummagene Transcription Factor Associations 2026	1.0	null
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03458
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03505
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8242
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
Embryonal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3336
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.59547
hsa-miR-4693-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-892a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Vomeronasal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4494
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
18855877-TableS2	GeneSigDB Published Gene Signatures	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0339
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974051
496100587_FWM_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64216
hsa-miR-885-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.298
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17377
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2198
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28357
spermatocytes	GeneRIF Biological Term Annotations	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12141
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.447
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1691
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6087
spermatogonia	GeneRIF Biological Term Annotations	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1102
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5025
Orchitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.072
Kartagener syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
Inhibin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.169
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978785
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.231
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03505
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3868
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5761
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0739
hsa-miR-4482	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6659
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.726
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4984
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7915
hsa-miR-589	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3612
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4466
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03081
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.09546
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.639
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56482
Turner syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9263
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8823
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2683
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14439
hsa-miR-204	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924096
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977919
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5504
hsa-miR-623	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-43-BNC1_BNC1	Rummagene Transcription Factor Associations 2026	1.0	null
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.257
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2188
Hypogonadotropic hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
Progressive leukoencephalopathy with ovarian failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
hsa-miR-3130-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.808
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36616
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1108
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925792
Androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.15
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3275
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4423
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4772
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.753
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2813
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3788
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52828
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9376
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64588
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.85
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.961
interacts	GeneRIF Biological Term Annotations	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1584
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.183
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1684
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47205
VDR-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Gonadoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.145
hsa-miR-1207-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870591
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90037
Seminoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Pituitary gonadotropin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.436
Olfactory placode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
UBE3A	Pathway Commons Protein-Protein Interactions	1.0	null
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47205
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4103
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978785
hsa-miR-122	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5166
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.762
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9881
hsa-miR-211	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Pseudohermaphroditism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.6106
hypospermatogenesis	GeneRIF Biological Term Annotations	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1166
Leydig cell hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.998
Spermatocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
hsa-miR-4792	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-200b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8053
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7656
immunonegative	GeneRIF Biological Term Annotations	1.0	null
Y-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7707
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08951
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43695
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
Kallmann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7196
hsa-miR-583	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
hsa-miR-508-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.671
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0371
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.312
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9797
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877848
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7791
maturation	GeneRIF Biological Term Annotations	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0401
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870591
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19037
Seminal vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03264
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869692
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6586
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.734
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.919
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.717
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869692
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548