association dataset threshold value standardized value Acrosomal matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.971 medial habenular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.945568 BCKDK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82006 SUDHL5 DepMap CRISPR Gene Dependency 1.0 3.3802 Ampulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.379 ANOS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0751 FU97 CCLE Cell Line Gene CNV Profiles -1.0 -2.5944 TC-71 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.42685 LB1047RCC DepMap CRISPR Gene Dependency 1.0 2.05381 ZNF219 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22365 HSFX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88967 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34356 SPI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMAT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40105 Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 70.1457 anion binding GO Molecular Function Annotations 2015 1.0 null Seminal vesicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.7 KIF13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.91178 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.34005 HINT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78723 MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.850643 UBE2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6385 Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.064 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.10382 Uterine fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.817 EFE184 DepMap CRISPR Gene Dependency 1.0 4.21845 Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZNF516 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27076 H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8481886-Table_1.xlsx-A_subsets-fetal_MSC_UC_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null CHD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37094 when GeneRIF Biological Term Annotations 1.0 null KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.943133 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053009 TMEM128 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79454 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Inner acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.873 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.927013 H1-6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17819 Blast Phase DisGeNET Gene-Disease Associations 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.965654 Leukemia DisGeNET Gene-Disease Associations 1.0 null ion binding GO Molecular Function Annotations 2015 1.0 null LS123 CCLE Cell Line Gene CNV Profiles 1.0 1.74396 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.54353 GSE224294_3_v_2_ngly1_human RummaGEO Gene Perturbation Signatures 1.0 null FOXF2 JASPAR Predicted Transcription Factor Targets 1.0 null Internode region of axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.725 ERCC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96601 PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6 Rummagene Transcription Factor Associations 2026 1.0 null PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK Rummagene Transcription Factor Associations 2026 1.0 null NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31444 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26055 H2BC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55219 SNU601 CCLE Cell Line Gene CNV Profiles 1.0 1.93888 LCLC97TM1 DepMap CRISPR Gene Dependency 1.0 4.00786 abnormality of the urinary system GWASdb SNP-Phenotype Associations 1.0 0.752335 Coleoptile TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.601 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PLEKHH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11243 NCIH2452 CCLE Cell Line Gene CNV Profiles -1.0 -1.52738 MYC ENCODE Transcription Factor Targets 1.0 null polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.47232 ATXN1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82167 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01421 SUPT20H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74017 gallbladder HPA Tissue Protein Expression Profiles 1.0 1.28042 SKM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.40063 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.863539 Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05356 OV90 CCLE Cell Line Gene CNV Profiles 1.0 1.41328 Sperm midpiece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.815 AIMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2995 CENP-A containing nucleosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.525 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.890539 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874806 KLF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 95.4076 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052712 hsa-miR-1287 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 ENSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95037 Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3871 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null breast HPA Tissue Protein Expression Profiles -1.0 -0.815459 Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRR11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22388 ERRFI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33874 GSTM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.4829 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null callosal sling Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.91345 outer SZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.841999 MYO19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40012 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GOLGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56514 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46632 HUPT3 CCLE Cell Line Gene CNV Profiles -1.0 -1.62194 ZSCAN32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8728 ARFIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23625 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040982 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DIFI DepMap CRISPR Gene Dependency 1.0 4.32142 cellular process involved in reproduction in multicellular organism GO Biological Process Annotations 2015 1.0 null GSE247764_0_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null DBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99375 Colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null secreted GeneRIF Biological Term Annotations 1.0 null seminal plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.736794 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.922681 SW 780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1496 PRDM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01378 outer CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.91035 many GeneRIF Biological Term Annotations 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12904 ZIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13596 FTSJ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14468 CYB5R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42631 COLO679 DepMap CRISPR Gene Dependency 1.0 4.46969 Epididymis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00501 small intestine HPA Tissue Protein Expression Profiles 1.0 1.28042 ZNF740 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 110.846 CGAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73648 Giant axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.574 496100383_HIP_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.51279 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46632 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67192 CREBBP ENCODE Transcription Factor Targets 1.0 null RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4571 reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17481 GARRE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81802 bronchus HPA Tissue Protein Expression Profiles 1.0 1.28042 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12621 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70538 FLI1 ChEA Transcription Factor Targets 1.0 null Glottis cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.44 SNU886 CCLE Cell Line Gene CNV Profiles 1.0 1.49427 hsa-miR-3135b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 RCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.47132 Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.794 FKBP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57176 Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCIH2342 CCLE Cell Line Gene CNV Profiles 1.0 2.16023 B3GAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12046 ALDOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56273 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71V-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.882897 NFYC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22722 SP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.45935 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.1141 NB4 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 MYC_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028822 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46632 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.887613 parathyroid gland HPA Tissue Protein Expression Profiles -1.0 -0.815459 Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.7407 TMEM201 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67941 SEMA3G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54402 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.943133 Spz1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.0833 Epididymosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.338 CTSZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78234 GSE210885_2_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null cell maturation GO Biological Process Annotations 2015 1.0 null Winchester syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.444 MAX ENCODE Transcription Factor Targets 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.995131 Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.089 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.87565 PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null ZNF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12538 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null OSBPL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33498 496100607_TCx_dementia_TBI_77_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.45624 CTCF ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09319 H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05301 SEPTIN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90206 GLI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82064 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single fertilization GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE111247_11_v_1_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null outer CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03633 spleen HPA Tissue Protein Expression Profiles -1.0 -2.21701 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99372 TAF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11394 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7776 Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.11 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.839128 cumulus-oocyte complex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.968 NCIN87 CCLE Cell Line Gene CNV Profiles 1.0 1.5389 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QY-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null developmental process involved in reproduction GO Biological Process Annotations 2015 1.0 null ZNF460 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 218.135 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37084 KPNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.257 GSE111247_0_v_1_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06345 extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.93496 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36728 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31538 BECN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10751 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.942297 molecular_function GO Molecular Function Annotations 2015 1.0 null TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1951 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874806 NCI-H2369 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49689 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.10276 KLF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 92.7532 OXNAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09164 JHOS2 CCLE Cell Line Gene CNV Profiles -1.0 -1.45391 STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null Molybdopterin synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.411 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.943133 Sperm plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.508 Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urinary system disease GWASdb SNP-Disease Associations 1.0 0.201449 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.031 YARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09631 RAB42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43168 Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.6405 BAMBI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37152 ANKRD13D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33042 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58414 IRX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88158 KAP1-22055183-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Cervical mucus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.285 RT4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01669 COR-L88 COSMIC Cell Line Gene Mutation Profiles 1.0 null RPL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92319 UQCC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77618 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85153 pontine nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.91603 orthologue GeneRIF Biological Term Annotations 1.0 null magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46448 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUPHD1 CCLE Cell Line Gene CNV Profiles 1.0 1.37875 KCTD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70334 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Maxillary sinus squamous cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.433 epididymal GeneRIF Biological Term Annotations 1.0 null SKNDZ CCLE Cell Line Gene CNV Profiles -1.0 -1.59946 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045675 MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Arsenic CTD Gene-Chemical Interactions 1.0 null lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43911 epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.50433 kidney disease GWASdb SNP-Disease Associations 1.0 0.858922 NB69 DepMap CRISPR Gene Dependency 1.0 2.77184 OAW42 DepMap CRISPR Gene Dependency 1.0 2.49463 SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37657 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.844023 MFGE8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50723 recombinant GeneRIF Biological Term Annotations 1.0 null skeletal muscle HPA Tissue Protein Expression Profiles -1.0 -0.815459 chromosome, centromeric core domain COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.506 496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.79135 496100498_PCx_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.6997 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.941439 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9692 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31619 MCRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99814 RCAN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95717 Fibronectin fibril COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.597 BRMS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7664 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31444 FAM120AOS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80984 hsa-miR-4256 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.3042 RMDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80291 disease GWASdb SNP-Disease Associations 1.0 0.024911 Germarium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.537 NCIH1623 CCLE Cell Line Gene CNV Profiles 1.0 1.56051 C10orf105 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30867 single organism reproductive process GO Biological Process Annotations 2015 1.0 null A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54962 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.43568 HCC1195 CCLE Cell Line Gene CNV Profiles -1.0 -2.13754 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PIERCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16973 Primitive endoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.608 FUBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10576 coli GeneRIF Biological Term Annotations 1.0 null Frt TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.845 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43706 Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null seminal vesicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.19178 Bulbourethral gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.79 SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09248 Brain Lower Grade Glioma_LGG_TCGA-QH-A6CZ-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UROS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81978 HUCCT1 COSMIC Cell Line Gene Mutation Profiles 1.0 null paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.51489 FGF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09394 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.86032 Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.960037 REEP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96021 Scrapie DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.408 TRIM25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19522 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE224294_4_v_2_ngly1_human RummaGEO Gene Perturbation Signatures 1.0 null GAA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2612 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49595 GSE111247_2_v_1_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null Cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.28 ASCL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03841 AGS CCLE Cell Line Gene CNV Profiles 1.0 1.68177 Trophoblast giant cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.007 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.3041 POLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68588 SLC36A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52012 H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76428 MAZ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 373.691 Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Myeloid Leukemia DisGeNET Gene-Disease Associations 1.0 null CD177 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56563 HT1376 CCLE Cell Line Gene CNV Profiles -1.0 -1.349 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4864 vesicles GeneRIF Biological Term Annotations 1.0 null lymph node HPA Tissue Protein Expression Profiles -1.0 -0.815459 ERVV-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63292 lowdensity GeneRIF Biological Term Annotations 1.0 null 496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.0005 496100377_PCx_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.43138 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05455 TLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38978 HS-74 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.036 cochlear nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861697 NAT8L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17838 PRKAG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64943 PAFAH1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79393 Rectum adenocarcinoma_READ_TCGA-CI-6624-01C-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM86C2P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2546 IGF1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53277 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10382 Water vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.376 stratum lacunosum-moleculare of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00308 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19982 ZNF148 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 456.875 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7306-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB157 CCLE Cell Line Gene CNV Profiles -1.0 -2.15694 RMUGS CCLE Cell Line Gene CNV Profiles 1.0 1.86446 SOX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94505 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.0741 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.842711 reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.849803 Prostasome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.508 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6436 SLC17A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62008 NCIH1581 CCLE Cell Line Gene CNV Profiles -1.0 -1.39214 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875871 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 SNU869 DepMap CRISPR Gene Dependency 1.0 2.14494 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.17867 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CREBBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Zona pellucida TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.004 CAL72 DepMap CRISPR Gene Dependency 1.0 5.40428 FAM43A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37521 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SZ in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06087 Salivary gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CD81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2023 ZNF684 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.5991 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.949821 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31444 AGPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52159 GCIY COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 B3GAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07339 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_11_CCF-Affected_Genes_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null DGKE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3781 GAS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99003 Prion disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.052 M1 melanoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.715 RNASE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33372 NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08653 abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.064684 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Nasopharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31614 Bladder GTEx Tissue Gene Expression Profiles 2023 1.0 5.31334 CHAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44451 MEAK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67826 epididymis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.0702 TRIM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45218 LNCAPCLONEFGC CCLE Cell Line Gene CNV Profiles -1.0 -1.78406 single-organism process GO Biological Process Annotations 2015 1.0 null Oviduct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.282 ZNF707 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 134.984 TP53BP1_KD_GSE54268_669_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66308 GSE210682_2_v_3_methadone_human RummaGEO Drug Perturbation Signatures -1.0 null NB-4 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 SNU-719 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.929384 Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Polar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.598 496100588_TCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.43831 KINGS1 DepMap CRISPR Gene Dependency 1.0 2.12319 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.30013 SF172 CCLE Cell Line Gene CNV Profiles 1.0 1.57469 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1673 FAM76A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73724 reproductive process GO Biological Process Annotations 2015 1.0 null DNAJB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85699 GIPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77349 accumulates GeneRIF Biological Term Annotations 1.0 null Prdm15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.0568 MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02415 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875871 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.890539 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09319 CCNYL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34759 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06748 TBX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2664 CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -1.59059 cerebral cortex HPA Tissue Protein Expression Profiles -1.0 -0.815459 Maxillary sinus cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.328 GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 90.2829 VZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44984 H2BC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59098 Sperm head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.365 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12679 KCTD21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57171 TSNAX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8543 NPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51951 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0151 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.890539 developmental process GO Biological Process Annotations 2015 1.0 null intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041353 cs96 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.174 Antipodal site COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.764 Seminal plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.517 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040791 Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rhabdomere COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.615 H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.5678 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24406 KYSE-510 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08078 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16175 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00713 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31168 Zona pellucida receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.278 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19473 VEGFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4993 ONS76 CCLE Cell Line Gene CNV Profiles -1.0 -1.38083 liposomes GeneRIF Biological Term Annotations 1.0 null HCE4 DepMap CRISPR Gene Dependency 1.0 3.73625 Gerstmann-Straussler-Scheinker syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.168 Reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.826 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.92014 PMC12480102-41525_2025_515_MOESM2_ESM.xlsx-ST12-Unnamed_2_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null DBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59702 hsa-miR-3185 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 KLF17 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.1277 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063875 shares GeneRIF Biological Term Annotations 1.0 null OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16506 ZNF135 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 234.634 Secondary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.968 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.86284 EVSAT CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24117 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC4A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03133 cell part GO Cellular Component Annotations 2015 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.028797 Cervicovaginal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.608 sperm capacitation GO Biological Process Annotations 2015 1.0 null ARG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7088 WM88 DepMap CRISPR Gene Dependency 1.0 2.57421 CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3363 PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S4-Table_S4_Top_500_differentially_modified_gene_bodies_between_AA_and_EA_patients_with_MM_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null RT4 CCLE Cell Line Gene CNV Profiles 1.0 1.36123 HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07025 TMEM17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01882 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.992478 phosphatidylcholine GeneRIF Biological Term Annotations 1.0 null lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -2.21701 Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RSL1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43208 U87MG CCLE Cell Line Gene CNV Profiles -1.0 -1.66886 496100331_TCx_probable Alzheimer's disease_TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.33057 outer SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14874 D423MG DepMap CRISPR Gene Dependency 1.0 7.81803 NCI-H647 COSMIC Cell Line Gene Mutation Profiles 1.0 null THAP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66462 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3476 TNKS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53593 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9757 biological_process GO Biological Process Annotations 2015 1.0 null FOXA1 JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13274 MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44357 NCIH2286 CCLE Cell Line Gene CNV Profiles -1.0 -1.50729 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.839128 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.98678 cytoplasmic membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.06635 Oviduct epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.11 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.994777 HCT15 DepMap CRISPR Gene Dependency 1.0 2.20049 Pharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SHPK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59092 H3K27me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null developmental maturation GO Biological Process Annotations 2015 1.0 null Pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.088 PC3 DepMap CRISPR Gene Dependency 1.0 2.6783 Bronchoalveolar system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 escherichia GeneRIF Biological Term Annotations 1.0 null Spectrosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.878 Exocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CCDC28A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14572 Perivitelline space COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.51 heparin binding GO Molecular Function Annotations 2015 1.0 null ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.3736 ARFGEF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87184 reticular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.870956 EDARADD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95107 ACOT13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70082 PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63 Rummagene Transcription Factor Associations 2026 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01421 NCIH1694 DepMap CRISPR Gene Dependency 1.0 2.42828 GSE224294_1_v_2_ngly1_human RummaGEO Gene Perturbation Signatures 1.0 null NDUFA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29155 A172 CCLE Cell Line Gene CNV Profiles -1.0 -1.59649 496100646_TCx_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.54587 GCIY CCLE Cell Line Gene CNV Profiles 1.0 2.36178 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49689 SP5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.5486 secretory granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.171937 inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11286 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YIPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2497 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.93577 stratum pyramidale of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.825819 GSE145915_5_v_4_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23019 SCH COSMIC Cell Line Gene Mutation Profiles 1.0 null Renal inner medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.854 LMNB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41803 carbohydrate derivative binding GO Molecular Function Annotations 2015 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.097 HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36242 Brain Lower Grade Glioma_LGG_TCGA-DH-A669-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.942297 TRMT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.93359 Oviductal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.154 PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.2357 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.065 496100556_TCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.78697 KARPAS299 CCLE Cell Line Gene CNV Profiles 1.0 2.59929 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNU878 CCLE Cell Line Gene CNV Profiles 1.0 1.82811 496100657_FWM_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.60597 DGUOK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49457 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041911 P2RY11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07334 KLF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 127.905 METTL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78578 SAR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.113 PAIP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71823 496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.63694 SF126 DepMap CRISPR Gene Dependency 1.0 3.83288 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 70.0359 Glottis squamous cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.036 496100378_TCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.88303 Fusome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.769 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07025 H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65147 tag GeneRIF Biological Term Annotations 1.0 null Spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.277 lipoproteins GeneRIF Biological Term Annotations 1.0 null ZSCAN30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46486 PNLDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26141 EZH2 ENCODE Transcription Factor Targets 1.0 null extracellular region GO Cellular Component Annotations 2015 1.0 null TTLL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86828 RFNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37717 FEV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11824 Respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZBED4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86544 LARP4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69795 DOTC2-4510 COSMIC Cell Line Gene Mutation Profiles 1.0 null EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 99.2383 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.600881 MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.12689 GSE105169,GSE105175_0_v_1_dhx36_human RummaGEO Gene Perturbation Signatures -1.0 null RI1 CCLE Cell Line Gene CNV Profiles 1.0 1.8712 Epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.898 PMC12480102-41525_2025_515_MOESM2_ESM.xlsx-ST12-Unnamed_3_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.4125 Paranasal sinus cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 sulfur compound binding GO Molecular Function Annotations 2015 1.0 null Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 POMC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34934 B4GALNT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94054 GLS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90483 inclusion body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.365477 Kringle-like fold InterPro Predicted Protein Domain Annotations 1.0 null DDHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77711 NCIH1339 CCLE Cell Line Gene CNV Profiles 1.0 1.51806 KLHL42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98863 sperm GeneRIF Biological Term Annotations 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23866 TBKBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15091 Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4477a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE145915_0_v_2_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CoA-synthesizing protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.849 outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29682 TRMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94743 LACTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99515 prostate HPA Tissue Protein Expression Profiles -1.0 -0.815459 characteristics GeneRIF Biological Term Annotations 1.0 null urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.856 CORO1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75024 cell surface GO Cellular Component Annotations 2015 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null KXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37482 ELP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69778 Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ES8 DepMap CRISPR Gene Dependency 1.0 4.33964 GSE228181_3_v_1_idh1_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100650_TCx_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.45495 Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE165274_1_v_2_poldip2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NFKBIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28047 NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.15714 496100297_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.59889 H3K27me3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100371_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.13427 GSE111247_14_v_1_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null pretectal nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.894048 T47D COSMIC Cell Line Gene Mutation Profiles 1.0 null AGS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32312 METTL24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52162 ZNF768 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.9166 supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01157 DUX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5201 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08899 CENP-A containing chromatin COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.506 C2orf68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9282 TFDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83432 Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null H3K27me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RU-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.1995 Brain Lower Grade Glioma_LGG_TCGA-HT-8111-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64776 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -0.815459 PCI30 DepMap CRISPR Gene Dependency 1.0 5.03224 behaves GeneRIF Biological Term Annotations 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051183 TGFBR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91576 MTMR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62397 MATN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07547 496100602_TCx_dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.29572 AGXT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.49361 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TRMT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2267 Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.528 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31444 NKX6-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02165 single-organism developmental process GO Biological Process Annotations 2015 1.0 null COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25475 Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Hmx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.026 TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.943133 SMIM24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04497 PUS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40058 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.856 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.840643 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874806 TMA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74786 CCDC115 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20875 THBD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50735 sperm part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.105028 Endocytic vesicle lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.047 Caput epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.592 496100636_FWM_probable Alzheimer's disease_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.57888 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37657 496100593_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.95646 Glottis carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.46 Cortical granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.582 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875871 fallopian tube HPA Tissue Protein Expression Profiles 1.0 1.28042 nasopharynx HPA Tissue Protein Expression Profiles 1.0 1.28042 Bronchus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045159 Gall bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZNF713 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39699 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.890539 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cell surface COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 CBX2-27304074-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36242 nucleus subputaminalis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.868853 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TC-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null liver HPA Tissue Protein Expression Profiles -1.0 -1.45082 LTBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38235 Cell envelope Sec protein transport complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.914 MZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3739 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.848 Blood microparticle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.727 Awn TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.5 Female pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.661 ZNF511 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66951 SNU620 CCLE Cell Line Gene CNV Profiles 1.0 1.3385 ZNF273 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71292 Sperm fibrous sheath COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.043 NCI-H3122 COSMIC Cell Line Gene Mutation Profiles 1.0 null SP in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24528 OVCA433 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE247764_1_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null mpkCCD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.828 AKTIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22066 Bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 342.579 FRAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64051 OSC19 DepMap CRISPR Gene Dependency 1.0 6.24063 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.839128 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08078 ZNF189 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 80.5928 H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7462 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.7249 HMC18 CCLE Cell Line Gene CNV Profiles -1.0 -1.83389 Cystocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.994 Epididymal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.657 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49689 SAP30L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91505 hsa-miR-3658 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.509197 cell surface COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 H4 CCLE Cell Line Gene CNV Profiles -1.0 -1.43782 SPI1 ENCODE Transcription Factor Targets 1.0 null NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46632 NCCRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95105 SW1417 CCLE Cell Line Gene CNV Profiles 1.0 1.3541 RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.7799 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874806 CNEP1R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78888 NCIH2170 CCLE Cell Line Gene CNV Profiles 1.0 1.80114 Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 43.627 ZNF460 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81345 ERI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60162 Myosin II filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.838 GSE92614_1_v_0_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF275 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89632 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.916064 496100457_TCx_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.259 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7886 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8267 DHX34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93459 CEP164 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.93729 VEZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.2787 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32148 seminal GeneRIF Biological Term Annotations 1.0 null RL CCLE Cell Line Gene CNV Profiles -1.0 -1.9597 NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.49189 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32312 FOXF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50464 Oviduct TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SCAMP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01865 nterminal GeneRIF Biological Term Annotations 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bodies GeneRIF Biological Term Annotations 1.0 null DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.4807 MCM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49789 LRRC8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45431 Stat2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 75.9197 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.09651 membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.065335 Sperm flagellum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.015 Fibronectin, type II, collagen-binding InterPro Predicted Protein Domain Annotations 1.0 null glycosaminoglycan binding GO Molecular Function Annotations 2015 1.0 null SPIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71769 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.968299 Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.2236 KCNA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93312 B3GNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7156 NCI-H250 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 Internal female genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NFIC JASPAR Predicted Transcription Factor Targets 1.0 null fertilization GO Biological Process Annotations 2015 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54962 PNGase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.838 496100564_TCx_no dementia_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.26034 Lung TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KLF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8213 UACC893 DepMap CRISPR Gene Dependency 1.0 18.241 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3895 Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.6454 hsa-miR-370 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 TC71 CCLE Cell Line Gene CNV Profiles -1.0 -2.31006 PIGW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83176 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.842384 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IHF-DNA complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.535 Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.5207 cellular developmental process GO Biological Process Annotations 2015 1.0 null layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09028 PIGM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77893 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.3328 principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.909922 YMB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.49148 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36874 H3K27me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PSN1 DepMap CRISPR Gene Dependency 1.0 4.12231 C22orf23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73006 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1882 hsa-miR-3074-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 DOK DepMap CRISPR Gene Dependency 1.0 3.56732 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0082 Visceral mass TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.312 REEP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93881 Outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.593 Outer acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.827 CLN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27907 STK25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79896 TAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22409 similarly GeneRIF Biological Term Annotations 1.0 null tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03424 bl21 GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null de3 GeneRIF Biological Term Annotations 1.0 null GSE122215,GSE122217_0_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.519647 MBOAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15992 ARAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68166 NCCSTCK140 CCLE Cell Line Gene CNV Profiles 1.0 1.6974 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3635 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16392 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76607 bsp GeneRIF Biological Term Annotations 1.0 null cytoplasmic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.065335 SNUC1 DepMap CRISPR Gene Dependency 1.0 8.91053 NIHOVCAR3 CCLE Cell Line Gene CNV Profiles -1.0 -1.35086 salivary gland HPA Tissue Protein Expression Profiles 1.0 1.28042 LNCAP Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.85139 prostate gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.074994 SLC20A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23619 H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null LIFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15994 Kidney - Medulla GTEx Tissue Gene Expression Profiles 2023 1.0 4.52292 hsa-miR-4530 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.23717 ZBTB7C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2569 H2AFZ ENCODE Transcription Factor Targets 1.0 null 9+2 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.916 Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.73708 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.027887 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67971 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049073 SNU46 CCLE Cell Line Gene CNV Profiles -1.0 -1.90671 CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.526 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DNAJC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89372 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21045 ventral posterior medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.227 Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 single-organism cellular process GO Biological Process Annotations 2015 1.0 null SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77522 bound GeneRIF Biological Term Annotations 1.0 null STX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20375 Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MICOS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90259 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07025 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.890539 GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.107 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875871 RL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.13314 Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.612 AGS COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0082 CDR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14686 PK59 CCLE Cell Line Gene CNV Profiles 1.0 1.87309 murine GeneRIF Biological Term Annotations 1.0 null MZ in retrosplenial cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26948 ZNF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56121 PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null DKMG DepMap CRISPR Gene Dependency 1.0 2.32463 MCOLN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07621 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 106.059 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6598 vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.063945 Brain Lower Grade Glioma_LGG_TCGA-E1-5319-01A-01R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKN3 DepMap CRISPR Gene Dependency 1.0 4.43579 RERFGC1B DepMap CRISPR Gene Dependency 1.0 3.43272 THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 TPM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62728 EIF4E2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98274 Brain Lower Grade Glioma_LGG_TCGA-HT-7686-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4888-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nde TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.082 Brain Lower Grade Glioma_LGG_TCGA-DU-8167-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MV-4-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.843427 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7776 binding GO Molecular Function Annotations 2015 1.0 null WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875871 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null biochemical GeneRIF Biological Term Annotations 1.0 null MAPK8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19544 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 PEPD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86401 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5504 P4HB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09887 PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8091 STARD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11811 parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26813 NCIH1573 DepMap CRISPR Gene Dependency 1.0 2.01701 NCIH1781 CCLE Cell Line Gene CNV Profiles -1.0 -1.42591 ZNF75A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.266 VMRCLCD DepMap CRISPR Gene Dependency 1.0 5.06709 Perturb_15687_KO_Pten_SRP095406 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.3714 SEMA4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22196 ZNF263_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04096 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051675 CCNJL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52566 CAPAN1 DepMap CRISPR Gene Dependency 1.0 2.37674 hexahistidine GeneRIF Biological Term Annotations 1.0 null Gallbladder disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.856 CCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52076 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UNC50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39924 Eye-retinal bipolar neuron Tabula Sapiens Gene-Cell Associations 1.0 1.5 hsa-miR-4531 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.910996 ZNF214 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0052 ENSG00000170846 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69918 MSGN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76718 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 C1QTNF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06698 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049279 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.943133 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.941439 inclusion GeneRIF Biological Term Annotations 1.0 null Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.856 SP8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 103.152 Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null