association	dataset	threshold value	standardized value
LIPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0767
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5468
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3781
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45852
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40532
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC11781671-ppat.1012897.s015.xlsx-Tab_S1-S1_Table_The_detailed_information_of_DEGs_in_Huh7_cells_post_MSX1_overexpression_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91859707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04345
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K34405227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5862
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K96817767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17923
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97623
HMCB	CCLE Cell Line Gene Expression Profiles	1.0	1.64277
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23319
RAP1GAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37367
RBPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65982
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869166
HUH6	CCLE Cell Line Gene Expression Profiles	1.0	2.22106
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69872
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49963
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.457956
prochlorperazine-4439	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YQ-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adipiodone-3111	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EYA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91784
PMC8160578-JCB_202009147_TableS4.xlsx-MYBL2_targets-Genes_n_532_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
GLT8D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00416
BMPR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71505
spironolactone-2226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tetroquinone-4078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
profenamine-3038	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43239
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.925206
BRD-K41289356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01969
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FANCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58305
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	0.909823
terfenadine-2227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14833
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52464
TRMT10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
chlorhexidine-5403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K27823380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08352
IQSEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63768
bethanechol-5114	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
SEPTIN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31886
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18203
BRD-K10105458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14416
GSE48812_11_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31721
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52746
GSE149096_4_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
azathioprine-1528	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02205
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13008
clofilium tosylate-6830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.094351
BRD-K95033255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0755
metacycline-2901	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K73095160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03171
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21955645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28257
KCTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69071
carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.81983
TSPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25941
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GMCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82242
theophylline-3326	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88908047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03349
BRD-K31526203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22609
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3726
LPS141	DepMap CRISPR Gene Dependency	1.0	2.78419
WDR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22377
PLEKHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89513
MDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86016
naloxone-1506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7483-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
niridazole-3301	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
atovaquone-4201	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13415
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
HNF4A	ChEA Transcription Factor Targets	1.0	null
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54347
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0425
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31663
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1808
NCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.242
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14487
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29339
MAFK	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06617
Lung squamous cell carcinoma_LUSC_TCGA-22-1016-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55160477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73682
TBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94226
lidocaine-4421	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF552	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68176
ethionamide-4593	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	1.0	1.88585
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38916
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.87531
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77558
BRD-K09975370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31777
Pancreatic adenocarcinoma_PAAD_TCGA-M8-A5N4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
astemizole-2211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
HELZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55233
PCDHGC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49595
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56175
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
BRD-K57173429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03083
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81283
MAP7D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88292
BRD-K64953645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04422
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952529
ranitidine-2251	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AH-23848-6885	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26253
AKAP17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64976
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60719
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21196
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4263
BRD-K15769121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45614
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K90697690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99979
indometacin-453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.951056
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
MYDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01638
CORL95	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84651
proscillaridin-2920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42091
Acute Myeloid Leukemia_LAML_TCGA-AB-2912-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912699
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
metronidazole-1503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22986
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.4694
octopamine-3112	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isometheptene-3145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K66572611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16175
TRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7268
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4521
2-aminobenzenesulfonamide-5422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO320	CCLE Cell Line Gene Expression Profiles	1.0	2.03242
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909712
FOXJ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45178
FKBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55283
BRD-K50893227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10923
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.20703
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870856
pancuronium bromide-4393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19428
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
betahistine-2833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67354
todralazine-1841	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99375
tracazolate-2919	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K51207618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73483
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95467
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.17093
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64728664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03485
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
BRD-K94090114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08702
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16544
MRPL44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53121
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25902
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56868
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K01314849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19033
ES8	DepMap CRISPR Gene Dependency	1.0	2.51021
metanephrine-6734	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HS819T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76644
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myricetin-4090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2047
CNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77791
AKT1_knockdown_141_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.18161
G402	CCLE Cell Line Gene Expression Profiles	1.0	1.42741
p53 decamer	MotifMap Predicted Transcription Factor Targets	1.0	null
pyrithyldione-6801	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
latamoxef-4648	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050436
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67064
TPM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538775
EMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79507
bacitracin-3109	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24687
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14031425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34357
BRD-K03606830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50544
BRD-K72687327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45262
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14457
Adrenocortical carcinoma_ACC_TCGA-PK-A5HA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF627	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00893
indoprofen-3345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
azlocillin-5788	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.05728
PLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0881
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55332
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00725
ABCB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90157
enoxacin-5616	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8728
BRD-K30964167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15791
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60408
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_DN_AA_DN-AA_DN_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
cefixime-3247	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMAD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31057
AIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14429
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96769
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4751
zimeldine-5670	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A17902629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02589
dienestrol-6208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38312
BRD-A23345137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37733
DIDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77842
dipyridamole-4656	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44428
aciclovir-5278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09465
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFKFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62546
beclometasone-4580	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE237984_1_v_2_magi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SB-203580-6899	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ketotifen-3200	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
clonidine-4478	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.127627
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	1.16597
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81011
atropine oxide-6812	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K16403365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59508
BRD-K23429973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14417
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83352
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34926
carbamazepine-1683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24286
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.948174
BRD-K27841704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23179
myosmine-3737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K14538540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30816
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85958
Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP-320650-01-4557	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DCA_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19464
TC138	DepMap CRISPR Gene Dependency	1.0	5.10276
BRD-K50300854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65727
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89212
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85107
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4
PRR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80395
Prestwick-972-3132	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6446
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24832
PPARD	ChEA Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prazosin-6315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.0363
levopropoxyphene-5083	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1954	DepMap CRISPR Gene Dependency	1.0	5.15167
GSE114992,GSE114993_0_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HTRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.507
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.852811
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72808
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	1.52846
sulfafurazole-5257	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
prochlorperazine-5010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.36407
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95142134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36523
Cardiomyopathy, Dilated_Myocardial tissue_GSE3586	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.55869
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04813
cyclobenzaprine-4252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sulfanilamide-4474	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K72588970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23305
BRD-K70896405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44924
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	2.03374
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04533
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75984
niridazole-4621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
prednicarbate-3542	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42697646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09234
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954543
BRD-K09206831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02087
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17834
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50809
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15808
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68769
WDR45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49866
MBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82097
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964974
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832797
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SREBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15328
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91092
letrozole-4824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
wortmannin-5240	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
dorzolamide-3565	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85169
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78915
ADCK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8061
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35978
valproic acid-1240	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66833
RFWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39708
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65216
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78938
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895737
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09175
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.55282
THAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66462
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953519
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893184
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58352
WDR54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3319
BRD-A44046220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05823
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060526
BRD-K14470344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5844
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8226
methanthelinium bromide-5780	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K48046422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2488
skimmianine-5766	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01188
betulinic acid-4181	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88989
ALG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87004
FMNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1481
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54774
TTC642	DepMap CRISPR Gene Dependency	1.0	4.14335
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38377
BRD-K74107343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0259
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	2.17646
LBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56337
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
ZSWIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60299
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950643
BRD-K59099936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03517
5666823-609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
proguanil-2944	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_17268_KO_Sox30_SRP139811	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
DHRS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
karakoline-4763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89782
atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.23353
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83906
fulvestrant-310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-DX-A48K-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNU-0230031-3735	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K77525326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00789
BRD-K37803976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25672
CER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04528
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47162
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47509
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26056
APOBEC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2701
sirolimus-5218	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGFB_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97296
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.09208
BRD-K24166534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28365
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35081
BRD-K70322385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31095
BRD-K41690760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0339
gemfibrozil-2113	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
94T778	DepMap CRISPR Gene Dependency	1.0	13.4124
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PYROXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73199
BRD-K54595160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6837
MEPCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44463
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01188
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08573
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
telmisartan_rattus norvegicus_gpl4135_gse29445	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.83681
HEC251	DepMap CRISPR Gene Dependency	1.0	3.19906
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6727
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1782
Type 1 diabetes mellitus_pancreatic islet_GSE2254	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.74682
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K08899466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35069
IST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02184
PNPLA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32821
TPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86611
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.889595
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95001
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66679
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47221
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29215
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS2ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69716
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1724
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
meglumine-6685	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40344
dl-alpha tocopherol-3256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K34451734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13322
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14803
PANC1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.919796
nadide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08544
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24042
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	2.0524
BRD-K93011670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01271
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59702
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68348
10-methoxyharmalan-1743	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832797
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38637
Epithelial and subepithelial dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900914
haloperidol-5241	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GAMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40224
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34982
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.902515
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60958
hsa-miR-4495	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
oxyphenbutazone-4506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
5279552-960	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28952606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29646
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.17714
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69252
PRPSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54208
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16165
hsa-miR-4516	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K82805160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22265
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Downregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF891	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
C11orf98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43586
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32591
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95296
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60135
HELLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6043
CORO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32936
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995908
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24297
levobunolol-3354	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71315
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58716
Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61924304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55045
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45007
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67185
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44733
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93697231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.727
BRD-K27476975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17256
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69835
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.964982
IGF2BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94152
Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32787834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30285
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953047
etofenamate-2907	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
baclofen-1536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.37683
BRD-A26165232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13839
BRD-K48864953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14752
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9452
C19orf73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67323
ZNF837	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
DCAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72686
trichostatin A-3114	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
naloxone-5606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80625
BRD-K10696228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97222
CITED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0504
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54065
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	2.00068
ESCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
fluorometholone-5771	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K33805195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00128
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56968
LYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74192
theobromine-6613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6667-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27659
SKRC31	CCLE Cell Line Gene Expression Profiles	-1.0	-2.32759
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909712
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18174
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM185PE	DepMap CRISPR Gene Dependency	1.0	3.17585
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82919
BRD-K39326623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14309
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832797
FRA10AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62106
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16607
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-AIRE-HIT_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89985
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50246
ribavirin-6521	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-3133	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
gossypol-4762	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-CoV NSP16_Day4_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.88884
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30836
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.916
Perturb_15864_KD_LSD1_SRP228812	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.41
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.898347
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50218
BRD-K68683482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06167
BRD-K15262863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34992
CCIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85855
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64147
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CJ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915547
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77599
CJM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54366
HCC2157	CCLE Cell Line Gene Expression Profiles	1.0	1.67403
GSE222103_0_v_1_ybx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pravastatin-lactone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27148
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28156
BRD-K86300178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12717
BRD-K52551495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24388
CROCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85634
timolol-6483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.25508
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.343304
tolfenamic acid-2120	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18285
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	1.82098
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5839
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964765
SW620	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.109
TXNDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97352
SLC6A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44948
ARHGAP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50784
A-VN-1203-2004(H5N1)_Day2-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73743
aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.216332
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A464-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PABIR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78785
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7732
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3686
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45074
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3672
natamycin-3548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76124
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40797
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53777
BRD-K28752165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64825
BRD-K82335556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47085
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61536
hydrastinine-2119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9554
TBC1D14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8319
dicoumarol-4323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	2.92282
Prestwick-692-4424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
practolol-5664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04159
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56466
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34031
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67144
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL_wt_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K78007953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65582
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17717
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20255
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80273
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38815
hsa-miR-330-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75054
BRD-K57315740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51802
U118MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35195
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93359
SERBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
metixene-6672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dicloxacillin-5012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87308
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.909823
BRD-K42679315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02316
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5368
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29026
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71271
GOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18984
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61564
EGR1	ChEA Transcription Factor Targets	1.0	null
citalopram-4555	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cotinine-5246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14098
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7047
PARD6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02729
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062341
RAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2346
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30722
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91263
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6032-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
doxylamine-1473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86638
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65935
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36561
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CANT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67296
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57094
BRD-K98545272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56486
KRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06462
BRD-K50272743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.51345
VPS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98919
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63318
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ATAD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47611
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.916
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.916
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36187
BRD-K39649723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42446
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16641
lobelanidine-2897	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUN-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71567
ISTMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8935
NCIH2030	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47996
ANKRD13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33042
profenamine-3376	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87351
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68092
ULK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67725
CTIP_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82433
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60573
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04785
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88763
lisuride-1545	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54402
Perturb_13927_OE_ESRRG_SRP363188	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.45512
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
alprostadil-6576	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU407	CCLE Cell Line Gene CNV Profiles	1.0	1.55276
RERFGC1B	CCLE Cell Line Gene Expression Profiles	1.0	2.16261
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.09491
clemastine-2412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.786
TTC709	DepMap CRISPR Gene Dependency	1.0	2.08496
BRD-K32124229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36584
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52514
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47646
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35328
REEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0157
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.909823
carmustine-6883	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02796
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76613
carteolol-3276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	1.9584
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27473
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74304
BRD-K13402127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18197
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99434
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22735
MAFF	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K88282877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36825
BRD-K73539077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31926
DPPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40681
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
HS688AT	CCLE Cell Line Gene Expression Profiles	-1.0	-2.29621
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01287
BRD-K88538240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07015
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.7272
colecalciferol-5002	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.52074
Androgen insensitivity syndrome_Fibroblast_GSE3871	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.83386
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	1.07907
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
BRD-K43326597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42221
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.990485
acenocoumarol-2240	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dinoprostone-6552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100483_FWM_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65184
BRD-K97067262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42383
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KF-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28674
TE125T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.47033
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10007
trimethoprim-3678	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
molecular_function	GO Molecular Function Annotations 2015	1.0	null
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09505
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_1424_KD_RUNX3_SRP159180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.93168
Adrenocortical carcinoma_ACC_TCGA-OR-A5JI-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48607
MAP3K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22324
BRD-K84439371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10704
BRD-K50085158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06156
betulinic acid-4101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CPNE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4592
BRD-K66632266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70061
BRD-K88974575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05062
trimethobenzamide-1502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K21479004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36195
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00577
PANK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04976
ERGIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77213
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11433
TPCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99667
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23787
hymecromone-5684	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.00374
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52091
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67142
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
RBBP5	ENCODE Transcription Factor Targets	1.0	null
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20985
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40216
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0457
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96938
PMC4773428-ncomms10751-s5.xlsx-S_Table_4-Supplementary_Data_4_RUNX1_responsive_genes_in_the_presence_and_absence_of_estradiol_E2_in_MCF7_cells_FC_1_5_p_0_05_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
metitepine-5413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-326	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
FANCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63727
perphenazine-5698	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE94768_3_v_2_pofut1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14166654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79552
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29127
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41738
YBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67625
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K95709431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07745
tropine-5790	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924426
HT55	CCLE Cell Line Gene Expression Profiles	1.0	1.35087
LY-294002-5970	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40802
SPI1	ChEA Transcription Factor Targets	1.0	null
AXIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39929
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36024
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19022
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acebutolol-4976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83371
CA-65-MK91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.28239
NAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76978
20502458-TableS6f	GeneSigDB Published Gene Signatures	1.0	null
fluorocurarine-5741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lisinopril-2371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pizotifen-3134	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
niflumic acid-2399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dinoprost-5409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28471
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
PMC10164164-41598_2023_34435_MOESM2_ESM.xlsx-FSK_CIC_KO_cp_to_CTL-gene_name_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60589
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LRRC10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37977
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20775
SPAG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38639
PDXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44509
RD	CCLE Cell Line Gene Expression Profiles	1.0	2.44548
methoxamine-2848	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
ZNF438	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21356
CD177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50435
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81232
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0157
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84174
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82048
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43585
BRD-K50036850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58048
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05123
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64067
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80848
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07639
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74395
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88353
SEMA4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22196
hsa-miR-4768-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94644
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.59745
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42684
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04924
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23428
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
FBXL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21048
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19992
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nalbuphine-2225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
hsa-miR-3122	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
trihexyphenidyl-2158	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63323
PKP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46936
PRKAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53014
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83122
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM63B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6275
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59968
Brain Lower Grade Glioma_LGG_TCGA-P5-A72X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY-294002-5236	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-981-6504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36129
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09558
biotin-2428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57168
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954543
BRD-K27539817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04954
BRD-K43889095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00575
ATP5F1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88918
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43281
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15127
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.936658
proxymetacaine-6332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STXBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78572
KD	DepMap CRISPR Gene Dependency	1.0	2.7655
sertaconazole-6811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85154
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0853
BRD-K74817844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25939
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11753
BRD-K22137463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48063
hycanthone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26112
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30117
moroxydine-1527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
STRA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8907
phenacetin-2471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59041191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41501
BRD-K65392908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27782
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78275
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.218034
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856414
arachidonic acid-441	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
naproxen-1828	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
terguride-6473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K85708426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23395
BRD-K51733045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43292
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40205
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02265
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67664
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61612
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93155
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A_CA_04_2009_7dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.32384
PMC11390959-41598_2024_70075_MOESM3_ESM.xlsx-520_DMD_common_down_gene_list-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
glycocholic acid-3315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EIF5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90811
AGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42191
Pauciarticular juvenile arthritis_Peripheral blood mononuclear cell_GSE1402	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.71098
cefuroxime-6261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76893
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987612
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_DN_NR2F1_ind_DN-NR2F1_Ind_DN_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
amoxapine-1513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55289
chloropyrazine-5750	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K31554491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0917
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5371
hydroxyzine-1524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DU4475	DepMap CRISPR Gene Dependency	1.0	3.12505
BRD-K86631750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06192
BRD-K16641781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32108
RAB39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86868
ZMIZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75013
TLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65833
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76821
Perturb_7930_KD_ZCCHC8/ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60671
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48622
epivincamine-6838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87774
ketoprofen-3729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
velnacrine-3292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C2CD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54406
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04458
nalidixic acid-3668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREBRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96022
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
COL9A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44012
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32999
cyclobenzaprine-3268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU182	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83313
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21412
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K25710391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68305
metoclopramide-4750	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28648
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.68423
VAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45258
SP140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46128
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31017
LY-294002-1216	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CPSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39563
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	7.68194
TATDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1014
BRD-K14599588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32855
emetine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5849
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30347
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87404
Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18739
ZNF700	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12127
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.02476
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2981
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59128
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13426
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89276
meclofenamic acid-2128	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COMMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15643
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-2.63606
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K96101240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16937
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44033
NLRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41186
alpha-estradiol-1151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
THAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7665
SOX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5078
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37878
naringin-2425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mesoridazine-2874	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77876
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29435
BRD-K92446632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00615
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12989
BRD-K39985369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30647
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40371
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91274
ETFDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21938
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22941
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62588
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77619
GSE174506_0_v_1_ror2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92933
LRATD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74053
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.78241
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42044
RHOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31705
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
fenbufen-3721	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.24273
OLIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23616
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42321
NLRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13659
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K41008930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46715
vigabatrin-5415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COX5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37055
BRD-K84233319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30186
PDZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44532
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924426
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05905
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63941
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893742
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NSUN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
OUMS23	CCLE Cell Line Gene Expression Profiles	1.0	2.58095
1min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	-1.0	null
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epithelial basement membrane dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64366
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	4.42793
DYNLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45842
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87918
BRD-K87754766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07971
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66236
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855052
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03066
H2BC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43642
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46728
BRD-K04680784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47316
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
TGFBR2_knockout_296_GSE22989	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.35268
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07414059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56408
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
EDEM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
CAPZB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50344
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80389
mebeverine-6795	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K50603336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28069
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55007
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79749
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33163
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41229
NALOXONAZINE-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41645
BRD-K47349976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8865
BRD-K81644801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59604
NCIH2085	CCLE Cell Line Gene Expression Profiles	1.0	1.40815
BRD-K20351658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29075
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.233
FBXL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84608
BRD-K02471501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32848
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50696
CCK81	DepMap CRISPR Gene Dependency	1.0	2.24766
TSPYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5839
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28111
Prestwick-642-2815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2939
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5893-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57919
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A21814529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00898
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10337
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62367
PRSS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20176
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47517
fursultiamine-4975	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SJRH30	CCLE Cell Line Gene Expression Profiles	1.0	1.80491
CYBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64775
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39625
GSE142684_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164494_0_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytisine-5739	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
zardaverine-4209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
ascorbic acid-5407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01192
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35217
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89276
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	3.70915
BRD-K50859531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06575
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01188
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944998
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3112
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64104
RUNX1	ChEA Transcription Factor Targets	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
ODC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34512
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70663
felodipine-3295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31444
CTAGE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9923
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52202
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95518
LIVF001-009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37486
93T449	DepMap CRISPR Gene Dependency	1.0	7.88428
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862668
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31444
TALL1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05627
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.989421
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
DPYSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4994
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TW-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41706
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37955
CH157MN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45123
BRD-K54198678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50706
RNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95653
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr1_172460613_TATTG_T_b38	GTEx eQTL 2025	1.0	3.8765
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
troglitazone-5592	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41537
BRD-A52794651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2987
metampicillin-5540	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50492
CP-645525-01-7527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SHROOM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86217
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35324
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17646
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41005
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39718
Prestwick-674-2179	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25222
flunisolide-2168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89276
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68836
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94713
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96023
NUPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57271
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.47836
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11485
BRD-K89638177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.175
Abdominal aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
eldeline-4306	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
ampyrone-2086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49525275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08634
peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.214636
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064877
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18203
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13582
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01372
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32195
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
ethoxyquin-3764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34197
BRD-K89320330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49698
demeclocycline-4267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2980-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PITPNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.887
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14048
RIPPLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32543
BC-02-WF67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.983105
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83741
loxapine-1516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06626
ZNF541	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39605
BRD-K07755570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28342
BRD-K88351048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02528
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52542
BRD-K70254692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28491
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01197
LAMTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90578
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
TBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.747
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01352
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57946
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51903
Platelet Component Distribution Width Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-634	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
ALVA31	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.75381
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
monastrol-668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4434	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Protein of unknown function DUF4548	InterPro Predicted Protein Domain Annotations	1.0	null
PPP1R2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.663
BRD-K08300592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03298
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98595
C14orf119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46615
Glycosylphosphatidylinositol Biosynthesis Defect	DisGeNET Gene-Disease Associations	1.0	null
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73803
protoveratrine A-6618	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CALU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61361
naftidrofuryl-2622	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4153-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_UP_2_5-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52915
sertaconazole-4475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ST6GAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38403
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.0285
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30439
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	1.47822
BRD-K77101974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87439
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87012
Rectum adenocarcinoma_READ_TCGA-AH-6644-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96508
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91859
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23949
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04924
BRD-K61796560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08393
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26179
fludroxycortide-2184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K85802892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	6.19913
H3C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14025
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54374
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70085
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26559
CDK11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72158
bicuculline-2796	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32384
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69657
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19404
Hydrops Fetalis, Non-Immune	DisGeNET Gene-Disease Associations	1.0	null
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ATF3_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
xylazine-2132	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54682
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64818
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15538
BRD-K62294866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08518
BRD-K90819764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16987
SMDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
BCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04989
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	3.05096
tropicamide-4744	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08621
carbarsone-3991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
monocrotaline-7127	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84943
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53163
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995908
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17762
SET2	DepMap CRISPR Gene Dependency	1.0	2.59246
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5507
valproic acid-5206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acemetacin-2411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fluocinonide-3933	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37165
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89181
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRG_RXRG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76960042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20091
PRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94588
BACH1	ChEA Transcription Factor Targets	1.0	null
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909668
diltiazem-1532	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CDK4_knockdown_143_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.67651
molsidomine-2862	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04924
cefepime-3581	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K05896800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58555
PMC10164164-41598_2023_34435_MOESM2_ESM.xlsx-FSK_CIC_KO_cp_to_CTL-gene_id_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Red Cell Distribution Width Determination	DisGeNET Gene-Phenotype Associations	1.0	null
AMFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93165
nordihydroguaiaretic acid-203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84444
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
SPRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52003
HT1197	CCLE Cell Line Gene Expression Profiles	1.0	1.46814
prazosin-5416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2052	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.29865
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20502458-TableS6b	GeneSigDB Published Gene Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8992_KD_PAX9_SRP407074	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K93923246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04448
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ESRRG_ESRRG	Rummagene Transcription Factor Associations 2026	1.0	null
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0587
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21429
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45578
BRD-K24156533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60216
CHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.71275
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29677
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53468
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60596
NCIH2029	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66789
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE220	DepMap CRISPR Gene Dependency	1.0	3.13148
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94671
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
BAZ1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55682
cobalt chloride-454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluspirilene-6662	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9659_KD_SOX11_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.61106
haloperidol-1144	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60578
BRD-K93494062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12007
TLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98719
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1782
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCM1	DepMap CRISPR Gene Dependency	1.0	4.49646
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.902777
KPNSI9S	CCLE Cell Line Gene CNV Profiles	1.0	1.4741
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14554
BRD-K72794452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38899
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924426
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05471
PREB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51965
GORASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91938
KIF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09943
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0734
BRD-K29842194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24711
RH30	CCLE Cell Line Gene Expression Profiles	1.0	1.49922
Prestwick-860-3378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
miconazole-6615	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TM7SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76279
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941529
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62008
PC3	CCLE Cell Line Gene CNV Profiles	1.0	2.15683
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
TBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94722
FDFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2566
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
dacarbazine-6816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41458
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.06771
HS695T	DepMap CRISPR Gene Dependency	1.0	4.10413
cefoperazone-5424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69802
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53104
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11409
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57807
GSE205332_2_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K71817712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14648
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_24_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
DTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32094
MYL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53356
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12814
oxaprozin-971	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96958
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82524
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11542
BRD-K78961368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25353
BRD-K61687409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41249
TPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09136
ZFP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18751
BRD-K26273412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59812
ZNF280B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68408
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.927576
prostate	HPA Tissue Gene Expression Profiles	1.0	0.887496
BRD-K25039453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10119
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
benzonatate-1843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K58025976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77344
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86647
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73248
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30507
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76073
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924426
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55971
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
COX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47285
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
MT-ND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71983
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decamethonium bromide-2933	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82772
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
estriol-3563	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF701	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83503
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76667
DPYSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61494
USP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71062
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3913-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.906857
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84769529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40114
MFSD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27384
RHBDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5291
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63673
zoxazolamine-2625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80791
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.24273
phenformin-3622	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
propylthiouracil-4076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trimethoprim-4701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29625
GJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33669
IL17RB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62731
BRD-K91397206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73493
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.969061
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
seneciphylline-2140	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61924932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85042
GGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10859
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
OVCAR3	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.850657
ZNF217-24962896-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ciclosporin-4586	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NB1	CCLE Cell Line Gene CNV Profiles	1.0	1.56319
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28453
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.891701
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49886
PPP3R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11573
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.868361
BRD-K57586808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71106
ZNF735	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03014
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33863
BRD-K66401298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34101
amitriptyline-167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26999
deferoxamine-4317	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834575
BRD-A20731954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24999
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16259
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44295
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27207
valinomycin-5962	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AMO1	CCLE Cell Line Gene CNV Profiles	1.0	1.56909
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28392
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
TTLL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05207
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
APP	Pathway Commons Protein-Protein Interactions	1.0	null
nicergoline-5775	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TMK-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.12703
RCBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49272
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.62369
PMC12852376-SupplementaryFile1.xlsx-Supplementary_Table_S4-Analysis_of_the_association_between_QTL_and_iridocyclitis_using_MR_and_SMR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
DFFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03951
carbamazepine-1847	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94896
BRD-K71631414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33156
TSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5661
CTXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51411
BRD-K02749944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39285
BRD-K93774122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30536
DU4475	CCLE Cell Line Gene CNV Profiles	1.0	1.72652
BRD-K16838444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34326
JADE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27103
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
SNX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34185
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
geldanamycin-1228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18119
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67194214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32017
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73829
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88626
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72484
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1466
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34575
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99563
DNAAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65061
BRD-K06203932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85092
ARAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68166
KBTBD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49344
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01287
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29002
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40257
0min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
BRD-K52062350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7622
Perturb_15683_KD_G9a_SRP239382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
meclofenoxate-4729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853916
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35596
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	1.04333
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92403
BRD-K24512597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64148
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42324
BRD-K37219127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03418
nicotinic acid-6702	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aciclovir-1543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cyclopentolate-5734	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83904
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_11_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
TXNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78441
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3081
CL14	CCLE Cell Line Gene Expression Profiles	1.0	1.88189
amiodarone-3296	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10692
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07204
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4151-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3076
Perturb_17406_KD_EIF2AK1_SRP261169	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.11522
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35755
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870856
TMED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6597
SELENOF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24268
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52906
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31277
Lung adenocarcinoma_LUAD_TCGA-49-6767-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03981
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
BRD-K75772626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24079
ST6GALNAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84803
carboplatin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40371
PMC10713402-aging-15-205220-s005.docx-0-RBAK_RBAK	Rummagene Transcription Factor Associations 2026	1.0	null
heart	GTEx Tissue Gene Expression Profiles	1.0	2.18987
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16228
BRD-K24479270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47467
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53379
hsa-miR-4689	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89181
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.62906
BRD-K57468571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22763
PMC10679653-mmc2.xlsx-ISL1_KO_Markers_L-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
ERLIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42523
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
BRD-K69580972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71453
DENR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43861
Adrenocortical carcinoma_ACC_TCGA-OR-A5LN-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37955
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	5.41449
CORT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08633
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35934
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18454119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19915
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76695
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23241
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69I-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81G-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIVF001-017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5607
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52375
lasalocid-3360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chlorcyclizine-4367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
finasteride-3744	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11542
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93312
NCIH1703	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78412
SRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5768
nordihydroguaiaretic acid-6182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893742
Brain Lower Grade Glioma_LGG_TCGA-HW-8321-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859109
BRD-K87562020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51543
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
dihydrostreptomycin-2074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
10min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.704
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48536
RASL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86942
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU81	DepMap CRISPR Gene Dependency	1.0	3.09453
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
ZNF217	ChEA Transcription Factor Targets	1.0	null
CNIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87226
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
desoxycortone-6758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87791
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01951210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74907
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.916
SMCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94769
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6493
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63467
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
BRD-K90480740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33878
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
5707885-6390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K89524688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03895
piretanide-3567	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298883
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18203
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59209
chlortetracycline-1541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40876
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMPDL3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8931
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37717
BRD-K20554239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02263
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29147
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64736
SARS-CoV MA15_Day4-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.77387
ENC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31087
CP-690334-01-3823	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
icSARS-Cov_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.41519
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13271
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82319
RPRD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72365
JM1	CCLE Cell Line Gene CNV Profiles	1.0	1.36055
tanespimycin-5958	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51624
alvespimycin-5210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52864
ZFP64	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50001
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
homatropine-methylbromide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61998
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FSCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83757
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44099
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
SLR25	CCLE Cell Line Gene CNV Profiles	1.0	2.53814
ZBTB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73625
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32755
sirolimus-2667	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DMRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33114
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79554
Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-8115-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053818
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.11512
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912699
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SS-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38966099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20444
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15996
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95019
clozapine-5226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM50B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35357
FAM220A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90492
MET_knockout_248_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.02338
Perturb_8655_KO_ESRRA/ESRRG_SRP304242	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
USF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80094
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61599
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22599787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50765
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84057
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32206
BRD-K25305749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59295
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29259
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059731
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33072
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42486
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68466
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
coralyne-6317	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K62511324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1701
ZSCAN16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08375
BRD-K83981181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40386
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14693
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23545
colchicine-644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
piroxicam-2089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
phenindione-2868	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74193
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65778
FOXO3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.085
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87918
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26743
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CABLES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98701
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42145
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2450	DepMap CRISPR Gene Dependency	1.0	2.12165
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43274
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47801
NCIH2052	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
KMS20	CCLE Cell Line Gene CNV Profiles	1.0	1.57037
MTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81502
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32771
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57415
BRD-K28478559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7534
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32272
KYSE410	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51095
metanephrine-1515	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CLTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63012
boldine-4004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88083
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57733
hsa-miR-4314	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
BL41	CCLE Cell Line Gene CNV Profiles	1.0	1.82018
BRD-K51490301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00198
alverine-2110	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
nimodipine-5421	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
scopolamine N-oxide-2099	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
dexpropranolol-3553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
minocycline-2405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K07473245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34638
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55428
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38967
ZNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54858
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55773
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
Lung squamous cell carcinoma_LUSC_TCGA-85-8584-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45011
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825753
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910036
SKOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22509
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87918
ZZEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0377
picotamide-2233	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
decamethonium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32543
HT1197	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97685
MTARC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78623
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
pheniramine-1492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ebolavirus(EBOV)_1day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.017863
BRD-K69438930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18371
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-685-3683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70863
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92439
thioridazine-5227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14189
UMUC11	DepMap CRISPR Gene Dependency	1.0	3.14136
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82205
lomefloxacin-4745	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0622
fluvastatin-6691	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K56224420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28776
BRD-K68330990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67719
EIF3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55363
BRD-A03668899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29042
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39617634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12486
PIH1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88647
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45213
clotrimazole-5726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79436
TRIP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04886
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05432839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51818
GPR160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82315
BRD-K00938872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20652
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40974
BRD-A42246453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04924
CTTNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
prilocaine-3624	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
clonidine-6814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-559-2877	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
BRD-K26314798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02245
carcinine-1305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28927944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25619
GOLGA8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80561
TNFRSF10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8212
hsa-miR-4476	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31829
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08428
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08532
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04318
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
SEPTIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44267
PEAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0507
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69326
Acute Myeloid Leukemia_LAML_TCGA-AB-2834-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
URB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.061
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
SLC35B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40947
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35146
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924426
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82219
guanabenz-1544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61707
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.12703
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21429
BRD-K52552873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43194
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09478
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066091
EOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08903
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31444
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26185
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
TMED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55973
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0376
PGGT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23757
nystatin-4223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
19658189-TableS5	GeneSigDB Published Gene Signatures	1.0	null
TGFBR2_knockout_295_GSE45968	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.72149
etiocholanolone-3742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pronetalol-3984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C1GALT1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12391
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58495
KBTBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67722
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.916
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84918
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61347
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63099
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50538
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
zimeldine-4609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164494_0_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A04618830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4187
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37292
20min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	-1.0	null
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3682
levocabastine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37776
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
LN382	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19617
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41427
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4106
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19131
BRD-K40117723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04862
TMEM126B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70788
isocorydine-6843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
isosorbide-4742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A17741195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0215
BRD-K40507170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06322
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65895
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832797
KCNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07069
BRD-K28641265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09427
arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.231795
alpha-ergocryptine-4374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZMYM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59489
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05433
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	1.64518
BRD-K89141455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3216
SKMEL31	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05638
DLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7856
RPP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03051
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-common-common_genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_HL-60_and_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15351
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78688
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85961
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49196
DBNDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73797
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84377
BCPAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9022
COLO678	CCLE Cell Line Gene Expression Profiles	1.0	1.59459
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51586
hsa-miR-3689d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
C3orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11113
spiradoline-3818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K01250897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34647
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
BRD-K53199675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07735
BRD-K97362312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08828
PACSIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76624
DNAJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37701
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100386_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1932
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01188
etofylline-2093	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
THOC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00538
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86855
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938839
clozapine-2689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	1.03255
Parietal foramina	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12283
cotinine-4650	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
santonin-3795	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.33861
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16652
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94527
hexamethonium bromide-4965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90660470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05857
aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.878605
ramipril-6150	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66717
RNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92939
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25731
RASSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04097
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32836
BICR18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36927
hsa-miR-511	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31819
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
guaifenesin-4371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41304
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18123
TXNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24028
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31008
PMC12756533-mmc1.pdf-37-ZNF101_ZNF101	Rummagene Transcription Factor Associations 2026	1.0	null
ceftazidime-5054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922974
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13258
YY1	ChEA Transcription Factor Targets	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.09472
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
chr1_172446211_GA_G_b38	GTEx eQTL 2025	1.0	1.08284
MOLP8	CCLE Cell Line Gene CNV Profiles	1.0	1.59573
SOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5664
Kidney Chromophobe_KICH_TCGA-KL-8335-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH446	DepMap CRISPR Gene Dependency	1.0	3.5007
COL16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41949
GPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47033
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2108
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16376
ALKBH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19481
kanamycin-4625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96391
AQP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07147
LS1034	CCLE Cell Line Gene Expression Profiles	1.0	1.75449
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99266
Aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.46994
GSE171269_1_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16353
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24224
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thiamphenicol-1826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tolbutamide-2320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.87573
DSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6551
BRD-K30530468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01443
clofazimine-4682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90208
pipenzolate bromide-6821	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3705
ZSCAN22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79973
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05563
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918563
propylthiouracil-4157	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2354
BRD-K14061746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04393
icSARA deltaORF6_30Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.93281
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7971
aminohippuric acid-6453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
placenta	HPA Tissue Protein Expression Profiles	1.0	1.59466
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
NFYA	ENCODE Transcription Factor Targets	1.0	null
BRD-K99847716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50165
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82525
Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_CUTOFF_2_5_TOTAL-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K08110534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12649
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050436
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.68137
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2122
nitrofurantoin-4697	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20004
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42698
P2RY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92601
EDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67639
LMSU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64148
TRIM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36486
haloperidol-5563	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32936
NMRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09183
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931823
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992983
nordihydroguaiaretic acid-5583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
bacampicillin-3273	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
benserazide-6482	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
salbutamol-2344	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81306
PMC4823830-ncomms11171-s2.xlsx-GATA3_upregulated_genes-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.98389
PAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60924
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70192
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
ZNF717	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52355
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A907-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cloperastine-3408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dexamethasone-2242	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77489
MEF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3512
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sodium phenylbutyrate-341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76833108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1071
GPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64885
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35813
disopyramide-2408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A06471483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80564
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57425
hydralazine-2311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30561
SKN3	DepMap CRISPR Gene Dependency	1.0	2.47108
JRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72508
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K40061713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01702
ANKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81368
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48736
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
ADRA2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34595
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43366
TIMMDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79672
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67009
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-THP-1_MLL-AF9_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06062
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73376
BRD-K77221985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25981
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28189
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36758
Aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53504
LRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28946
WRAP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67093
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K08436070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30901
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10089296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22477
TMEM129	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82161
felbinac-5700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abdominal aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.95745
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56754
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40956
ZBED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40533
articaine-6517	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83727
naproxen-6794	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
OPM2	CCLE Cell Line Gene CNV Profiles	1.0	2.27319
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86952
SEMA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29305
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44621
valproic acid-4464	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18305
BRD-K61691014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15778
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79803
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90626
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04017
ZC3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52684
BRD-K64531971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96926
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.30056
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16806
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11614
phentolamine-2323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
muscle	GTEx Tissue Gene Expression Profiles	1.0	0.984113
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99972
myricetin-3270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mafenide-2124	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36762
BRD-K34414758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28155
amantadine-4222	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
0179445-0000-4758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5554
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69991
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.916
clebopride-5412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01287
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96136
withaferin A-3819	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PF-00562151-00-5959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TF-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55392659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28098
oxedrine-6798	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
merbromin-3700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
BRD-K98169006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87507
eticlopride-3393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CL11	CCLE Cell Line Gene Expression Profiles	1.0	1.37387
BRD-K54712090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29934
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2557
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54705
RPL29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15908
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70972
cinchocaine-1469	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23978
DLD1	CCLE Cell Line Gene Expression Profiles	1.0	1.44427
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.95814
BRD-K07384081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4097
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33816
spleen	HPA Tissue Protein Expression Profiles	1.0	0.909823
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34635
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862668
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.831882
BRD-K13637593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47149
ZNF785	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27319
Prestwick-984-4948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53265
BAIAP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69412
BRD-K07988588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33862
BRD-K17659275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72436
ethotoin-3809	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23317
BRD-A95480808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27233
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Rdw - Red Blood Cell Distribution Width Result	DisGeNET Gene-Phenotype Associations	1.0	null
Brachydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07438289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02128
RH41	CCLE Cell Line Gene Expression Profiles	1.0	3.40792
fulvestrant-1146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ethambutol-1481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SEBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42249
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.909823
BRD-K08666983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37692
KCNK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58897
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28347985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85817
ORMDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99664
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Prestwick-1083-2976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TTC549	DepMap CRISPR Gene Dependency	1.0	14.3315
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73607
YAMATO	DepMap CRISPR Gene Dependency	1.0	3.12601
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
ELF5	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K14161261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41389
SBK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78336
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69778
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09558
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
nabumetone-3108	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF548	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24361
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5254
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950643
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92586
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28298
BRD-K44932450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0471
BRD-K46623934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15083
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3664
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12143
LP1	CCLE Cell Line Gene CNV Profiles	1.0	1.61473
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	2.31941
BRD-A23955117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23029
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.13668
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68497273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20521
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7846764-41598_2021_81773_MOESM2_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2571
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.7621
SYNJ2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35357
MX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10214
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63766
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.831882
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R5-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
PF-00875133-00-5928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69419
tenoxicam-2501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	0.909823
SSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65482
nitrofurantoin-2303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
perhexiline-5081	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
propidium iodide-5803	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
wortmannin-506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050367
alvespimycin-4437	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CL40	CCLE Cell Line Gene Expression Profiles	1.0	1.4054
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digoxigenin-4680	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K64215435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12748
ADA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17162
clozapine-6188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
troglitazone-370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K20416270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13535
ZNF629	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4542
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71337
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37871
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21716
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37576
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55769
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.086314
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.916
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041669
CCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09899
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46944
BRD-K34310783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00756
USP51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.585
GTPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6003
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58171
NDUFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20536
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.808
BRD-K90693562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10745
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38456
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
BRD-K59984972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00747
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833761
BRD-K78120854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25496
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78559
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910036
VHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70521
BHLHA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53005
USP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07256
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59465
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862668
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
tanespimycin-1631	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.68584
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77095
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dihydroergotamine-2244	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
apramycin-2914	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21504
acebutolol-1493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pepstatin-1328	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DCHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45654
RRAGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89341
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52695
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52265
BRD-K35970781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12207
OPM1	CCLE Cell Line Gene CNV Profiles	1.0	1.51834
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45203
alpha-CP1	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70325
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81719
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7247-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2338
BRD-K62841356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03044
GSE216043_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GRHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19482
5155877-6574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TUG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72668
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-01A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.79677
Prestwick-967-4833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35823
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
GSS	CCLE Cell Line Gene Expression Profiles	-1.0	-2.49516
tranylcypromine-2101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1876	COSMIC Cell Line Gene CNV Profiles	1.0	2.12703
MINPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15663
tolazoline-1500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34423
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92203
HCC1569	CCLE Cell Line Gene Expression Profiles	1.0	1.58455
BRD-K70581786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11898
LS180	DepMap CRISPR Gene Dependency	1.0	2.82282
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00749
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13582
BRD-K29441085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53238
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0518
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.73125
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03948
lynestrenol-6756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K67460571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24626
SubthalamicNucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3765
LRRC4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19367
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138