association dataset threshold value standardized value JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4521181-oncsis201520x8.pdf-131-SETBP1_SETBP1 Rummagene Transcription Factor Associations 2026 1.0 null PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1 Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE217405_3_v_2_osimertinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE192870_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE125007,GSE125008_6_v_0_uhrf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null esophagus HPA Tissue Protein Expression Profiles 1.0 1.48737 GSE144838_2_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.960813 medial group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.999123 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16603 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBC1D3K CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63847 GTEX-UJMC-1226-SM-4IHLI GTEx Tissue Sample Gene Expression Profiles 1.0 0.840557 Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLR26 DepMap CRISPR Gene Dependency 1.0 2.4842 GSE172020_0_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null PPAN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72225 integral component of membrane GO Cellular Component Annotations 2015 1.0 null bonemarrow_6a HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 OVCA420 DepMap CRISPR Gene Dependency 1.0 3.256 ESC_J1_UP_LATE.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE120200,GSE127269_1_v_2_asxl1_human RummaGEO Gene Perturbation Signatures 1.0 null MCC142 DepMap CRISPR Gene Dependency 1.0 2.33167 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null isthmic portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36497 GSE188884,GSE189078_2_v_3_ebf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL1_GRHL1 Rummagene Transcription Factor Associations 2026 1.0 null DHX29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58747 Down Syndrome_Fetus_GSE10758 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.74243 GSE202434,GSE202438_12_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null XYLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84754 PMC3371315-NIHMS350140-supplement-12.xls-MCF7-T47D-SK-453_Down_Common_xl-Supplementary_Table_5_Luminal_Signature_Genes_decreased_in_all_four_cell_lines_MCF7_T47D_MB-453_SKBR3_with_knockdown_of_FOXA1_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null mRNA_TBX3_16767105 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-IRF6_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67114 GSE145249_0_v_2_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null GSE228727_2_v_1_dapagliflozin_mouse RummaGEO Drug Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23899 TAF1 ENCODE Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-US-A77G-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE182179_0_v_1_kdsr_human RummaGEO Gene Perturbation Signatures -1.0 null NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.901603 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Hyperplasia CTD Gene-Disease Associations 1.0 1.01966 Prostate adenocarcinoma_PRAD_TCGA-YL-A8HJ-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null GSE165122_0_v_1_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-Q2AH-1226-SM-48TZL GTEx Tissue Sample Gene Expression Profiles 1.0 0.994618 GSE135400_1_v_0_kdm1b_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retrosplenial area, lateral agranular part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13494 BEN CCLE Cell Line Gene Expression Profiles 1.0 2.25277 Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null perilemniscal isthmic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07763 posterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29498 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959712 GSE214212_2_v_1_chd6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE157894_1_v_0_cystine_human RummaGEO Drug Perturbation Signatures -1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null NB5 DepMap CRISPR Gene Dependency 1.0 2.34994 medial part of r1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03206 496100434_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.02846 GSE195559_2_v_7_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null r4 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09371 WDR83 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.124 superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.2982 MGAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00026 Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19957 Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BLTP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55339 Perturb_5040_KD_Smarcc1_SRP221174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -17.8827 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32709 GSE111035,GSE111040_3_v_12_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10712 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null DMRT1-23473982-TESTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE174701_5_v_2_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null Interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2711 periventricular stratum of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22543 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null GSE206729_2_v_0_trps1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MO-0726-SM-4DM58 GTEx Tissue Sample Gene Expression Profiles 1.0 0.888887 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959712 Arcuate hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20488 RNASEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25202 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67307 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7620-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver Cirrhosis, Experimental DisGeNET Gene-Disease Associations 1.0 null CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteroventral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21491 ASPC1 DepMap CRISPR Gene Dependency 1.0 2.00685 BHLHE40 ENCODE Transcription Factor Targets 1.0 null H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE85880,GSE85881_4_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null IMR32 CCLE Cell Line Gene CNV Profiles -1.0 -2.41098 H2BK120ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF705A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37778 heart_5a HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P4PP-1426-SM-3NM9L GTEx Tissue Sample Gene Expression Profiles 1.0 0.839148 CDC34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06245 CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8256-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4488-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100515_HIP_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.22246 ovary_8a HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 CALR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04188 inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.83857 GSE48812_0_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.52495 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null hsa-miR-3653 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Stomach Smooth Muscle Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.916696 mantle zone of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2711 ABRACL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32966 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.52214 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76643 ZBTB7A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pontine gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16412 CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE239844_11_v_2_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null MZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.19133 Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07361 CCDC85B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46476 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NOL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14695 lateral part of preisthmic periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22543 GTEX-XV7Q-2126-SM-4BRVX GTEx Tissue Sample Gene Expression Profiles 1.0 0.850756 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5611 CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15129 Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53948 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.950314 GSE205730,GSE205731_2_v_0_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null COX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32061 BHLHE40_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE118077_1_v_8_sprr5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE184892_6_v_3_trehalose_human RummaGEO Drug Perturbation Signatures -1.0 null 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0769 GSE160001,GSE160670_3_v_2_lapatinib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-T5JW-0926-SM-4DM5K GTEx Tissue Sample Gene Expression Profiles 1.0 0.838581 GSE241701_4_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE184892_6_v_1_trehalose_human RummaGEO Drug Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.919742 GSE152937_12_v_1_slc16a13_mouse RummaGEO Gene Perturbation Signatures 1.0 null KPNYN CCLE Cell Line Gene CNV Profiles -1.0 -2.10349 RAB11FIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97782 intermediate part of the arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32199 FOXA2 ENCODE Transcription Factor Targets 1.0 null r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.92709 MPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31513 Prostate adenocarcinoma_PRAD_TCGA-G9-6342-11A-02R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH727 CCLE Cell Line Gene Expression Profiles 1.0 1.95656 G53434XO GlyGen Glycosylated Proteins 1.0 null CREB1 JASPAR Predicted Transcription Factor Targets 1.0 null SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5033_KD_Smarca4_SRP221174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.39852 Anterior cingulate area, dorsal part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42264 sublayer 6a of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16396 ESR1 ChEA Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8111-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2 Rummagene Transcription Factor Associations 2026 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.883433 intermediate stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62902 GSE237040_2_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.918808 CTCF_HEK293_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12218 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53929 GSE128730_4_v_6_neratinib_human RummaGEO Drug Perturbation Signatures 1.0 null LAMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39959 dorsolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17407 YMB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.56646 SIN3A ENCODE Transcription Factor Targets 1.0 null GSE157594_5_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC10232817-Table_2.pdf-11-NR2C2_NR2C2 Rummagene Transcription Factor Associations 2026 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adrenal_4c HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 GSE76771_2_v_3_atf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Ventral medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09855 GSE149035_1_v_5_hepacam_human RummaGEO Gene Perturbation Signatures 1.0 null GSE248858_4_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE239688_2_v_5_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null GSE127790_9_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null m1 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17399 HCC1195 CCLE Cell Line Gene Expression Profiles 1.0 1.73511 KYSE30 CCLE Cell Line Gene Expression Profiles 1.0 1.56505 RAB33A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29573 mRNA_EOMES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF2 ENCODE Transcription Factor Targets 1.0 null PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gastrointestinal stromal tumor_Gastric Tissue_GSE15966 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.63449 SNU245 CCLE Cell Line Gene CNV Profiles -1.0 -1.46771 GSE48812_4_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_bone_marrow_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M1-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205163,GSE205164_2_v_0_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-75-5146-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFG8-1326-SM-4LVN3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0191 hsa-miR-761 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GTEX-TMMY-1626-SM-4DXTY GTEx Tissue Sample Gene Expression Profiles 1.0 0.876275 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.24894 EGR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE255432_4_v_3_imeglimin_mouse RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-3150b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 dorsomedial preoptic area, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30924 OE33 CCLE Cell Line Gene CNV Profiles -1.0 -1.44647 CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUZC-1626-SM-4BRVP GTEx Tissue Sample Gene Expression Profiles 1.0 1.46621 GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE114284_2_v_3_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null oral mucosa HPA Tissue Protein Expression Profiles 1.0 1.48737 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null temporal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.926656 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE127790_5_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34821 GSE157233_2_v_4_a1cf_mouse RummaGEO Gene Perturbation Signatures -1.0 null SP in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.859297 GSE245418_0_v_2_cd109_human RummaGEO Gene Perturbation Signatures -1.0 null CCLFUPGI0005T DepMap CRISPR Gene Dependency 1.0 3.06965 intermediate stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03206 Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE165704_0_v_1_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE158197_2_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null Temporal association areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69819 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5695-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42016 Ventromedial hypothalamic nucleus, dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89086 adrenal_4d HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXO1-23066095-LIVER-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HCC1588 CCLE Cell Line Gene Expression Profiles 1.0 1.65331 POLR2AphosphoS5_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24314 mantle zone of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44468 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05182 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAPZA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10384 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.827523 planum temporale, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24684 MAZ ENCODE Transcription Factor Targets 1.0 null superficial stratum of PCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2314 mantle zone of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62804 POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12732 CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MUSK Kinase Library Tyrosine Kinome Atlas 1.0 95.27 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18986 superficial stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14395 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SI-01A-31R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.50547 largeintestine BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07512 ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMRC2 DepMap CRISPR Gene Dependency 1.0 3.47693 Midbrain, behavioral state related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60398 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE174701_4_v_7_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null GSE236502_1_v_3_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null GSE120413,GSE120447_0_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null GSE220520_6_v_4_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-3922-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959712 H3K27me3_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUHR10TKB DepMap CRISPR Gene Dependency 1.0 3.70757 GLRX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35332 TCF3-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11076 GSE142232,GSE142234_0_v_3_gcgr_mouse RummaGEO Gene Perturbation Signatures -1.0 null CEBPB_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null QGP1 CCLE Cell Line Gene Expression Profiles 1.0 1.59877 GSE158197_6_v_10_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-544b TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null GSE146074_9_v_8_ly6e_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE174701_5_v_3_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null EIF2S3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35991 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NEIL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56157 Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63328 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null CREBBP ENCODE Transcription Factor Targets 1.0 null liminal periaqueductal gray of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62804 shell of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.137 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRAME CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05995 hippocampus (hippocampal formation)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.902052 POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null GSE147626_3_v_1_glutathione_human RummaGEO Drug Perturbation Signatures 1.0 null r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60189 Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23095 Primary somatosensory area, barrel field, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67817 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.96487 MKN74 CCLE Cell Line Gene Expression Profiles 1.0 1.45926 GSE180147_0_v_1_itga5_human RummaGEO Gene Perturbation Signatures 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49707 GSE168807_0_v_7_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03483 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.80567 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Thrombocytopenia_Megakaryocyte_GSE2527 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.77279 MZ in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18429 CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-1226-SM-4DM5H GTEx Tissue Sample Gene Expression Profiles 1.0 0.844251 Retrosplenial area, ventral part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13627 H3K27me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE239844_11_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null NUBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81381 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.36204 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46051 Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE229973_3_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-3662 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5181-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.985072 GSE226181_3_v_2_akt1s1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TCF12_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GSE114284_2_v_0_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.169 ZNF382 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0916 dorsolateral part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14614 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23335 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T5JW-1126-SM-4DM5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.958158 Lung squamous cell carcinoma_LUSC_TCGA-39-5034-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4151-01A-01R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null IM95 CCLE Cell Line Gene Expression Profiles 1.0 1.75959 GABPA_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial part of the isB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34991 GSE198794_0_v_1_usp18_human RummaGEO Gene Perturbation Signatures 1.0 null GSE239688_2_v_1_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE160373_8_v_2_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-451b TargetScan Predicted Conserved microRNA Targets 1.0 0.419947 Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.29071 Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4512 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GSE127790_11_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04117 KMS20 CCLE Cell Line Gene CNV Profiles -1.0 -1.87983 USF2 ENCODE Transcription Factor Targets 1.0 null LAG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05828 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THP1 CCLE Cell Line Gene CNV Profiles 1.0 1.34247 GSE146612_1_v_3_amiodarone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE96641_5_v_2_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null m2 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46206 HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.61148 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-4698 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 NCIH2286 DepMap CRISPR Gene Dependency 1.0 4.02076 hsa-miR-3121-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Primary somatosensory area, lower limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15363 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03899 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.17287 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38536 GTEX-QDVN-1226-SM-48TZ5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.970621 mRNA_SALL4_19060217 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ8I-2126-SM-4BOOM GTEx Tissue Sample Gene Expression Profiles 1.0 0.858503 NAPRT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20432 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25715 mantle zone of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05324 SP1 ENCODE Transcription Factor Targets 1.0 null skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 GSE216043_7_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null mRNA_OTX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15496 NANOG-16518401-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900365 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68853 layer 6 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52807 Taenia tecta, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08547 GTEX-U3ZN-2126-SM-4DXU1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.959053 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900365 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2BK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07977 TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23666 CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.896515 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5713-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67114 Koelliker-Fuse subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16412 intermediate stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44057 hsa-miR-125a-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.96306 NANOG ChEA Transcription Factor Targets 1.0 null PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-461-ENSG00000127124_HIVEP3 Rummagene Transcription Factor Associations 2026 1.0 null GSE173873_1_v_3_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38995 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC827GR5 CCLE Cell Line Gene Expression Profiles 1.0 1.42381 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.848829 GSE175787_11_v_6_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE239844_11_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE199874_4_v_5_gabpb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null stratum oriens of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.868255 hsa-miR-656 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE86507,GSE86509_7_v_2_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Ectorhinal area/Layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26531 A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44406 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-VN-1203-2004(H5N1)_Day4-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.7407 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16307 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRIX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06304 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26909 periventricular stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42016 LN215 CCLE Cell Line Gene Expression Profiles -1.0 -2.073 GSE62292,GSE62295_2_v_0_col4a3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Secondary motor area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30924 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2815_KD_LSD1_SRP310243 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SOX2 ChEA Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null JHOM2B CCLE Cell Line Gene Expression Profiles 1.0 1.6239 GSE76771_1_v_3_atf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55D-1826-SM-48FEF GTEx Tissue Sample Gene Expression Profiles 1.0 0.956548 KIT Kinase Library Tyrosine Kinome Atlas 1.0 96.04 hsa-miR-670 TargetScan Predicted Conserved microRNA Targets 1.0 0.17031 UCMA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73898 Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09678 SRPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82124 r9 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17802 PKIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32443 GTEX-Q2AI-0926-SM-48U1F GTEx Tissue Sample Gene Expression Profiles 1.0 0.935212 HTT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22884 GSE115363_2_v_4_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null nicotine_mus musculus_gpl1261_gse31004 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lateral terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21493 H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE130081,GSE130082_4_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00203 CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4478 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null endosome GO Cellular Component Annotations 2015 1.0 null HNF4G ENCODE Transcription Factor Targets 1.0 null UPMD1 DepMap CRISPR Gene Dependency 1.0 2.63264 Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE238116_1_v_2_egr1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QLQW-0426-SM-447A7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.939678 Prostate adenocarcinoma_PRAD_TCGA-YL-A9WH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null GSE147876,GSE147877_4_v_8_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null MST1R Kinase Library Tyrosine Kinome Atlas 1.0 95.43 HEL DepMap CRISPR Gene Dependency 1.0 2.27302 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFE2L2_NFE2L2 Rummagene Transcription Factor Associations 2026 1.0 null inferior olive, dorsal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0417 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76401 CAPAN1 DepMap CRISPR Gene Dependency 1.0 15.1806 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE202434,GSE202438_12_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04016 membrane part GO Cellular Component Annotations 2015 1.0 null GSE229914_2_v_3_keap1_human RummaGEO Gene Perturbation Signatures 1.0 null STAT3 ChEA Transcription Factor Targets 1.0 null HNF4A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE210655_1_v_6_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE205730,GSE205731_2_v_1_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC3290552-pone.0032232.s006.xls-MUC4-KD_vs_Mock-Unnamed_3_AR Rummagene Transcription Factor Associations 2026 1.0 null WHSC1 ENCODE Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE101537_4_v_2_neurog3_mouse RummaGEO Gene Perturbation Signatures 1.0 null RPL34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94626 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H5-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162739_4_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null parietal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2314 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-11A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FANCE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56655 CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62804 ZNF143 ENCODE Transcription Factor Targets 1.0 null GSE226397_0_v_1_cystine_mouse RummaGEO Drug Perturbation Signatures -1.0 null TRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10035 hsa-miR-940 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE158197_5_v_4_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE151829,GSE151831_1_v_8_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null KMRC3 DepMap CRISPR Gene Dependency 1.0 2.29903 GSE137818_3_v_7_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.70439 H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.843241 GSE229973_3_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null RCC4 CCLE Cell Line Gene CNV Profiles 1.0 1.74301 GTEX-P4PP-1526-SM-3P61M GTEx Tissue Sample Gene Expression Profiles 1.0 1.00124 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R4-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.938383 smallintestine BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 496100369_PCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.18357 r9 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12732 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null ESR1_01_111 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.64441 PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_2_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_2_Mesendoderm_FDR_0_05_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null NFIC ENCODE Transcription Factor Targets 1.0 null GSE174701_1_v_7_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE174701_5_v_8_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE65617_5_v_3_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-214 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11579 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4426 POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r8 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99346 GSE144500_8_v_2_ventx_human RummaGEO Gene Perturbation Signatures -1.0 null H3K27ac_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-203 TargetScan Predicted Conserved microRNA Targets 1.0 0.336728 IZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911327 HT1376 CCLE Cell Line Gene CNV Profiles 1.0 2.45058 placenta HPA Tissue Protein Expression Profiles 1.0 1.48737 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.986177 GSE199255,GSE199356_6_v_2_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null transverse gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00998 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47061 hsa-miR-3945 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 RRP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32051 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE218819_3_v_4_kdm5b_human RummaGEO Gene Perturbation Signatures -1.0 null NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22892 PSMB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94598 principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.901498 IVD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08278 mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18928 TCF3 ChEA Transcription Factor Targets 1.0 null L1236 DepMap CRISPR Gene Dependency 1.0 2.74832 GSE161864,GSE161866_4_v_3_ror2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE155162,GSE155169_1_v_0_buparlisib_human RummaGEO Drug Perturbation Signatures -1.0 null EGR1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPIB JASPAR Predicted Transcription Factor Targets 1.0 null GSE57871_1_v_2_vorinostat_human RummaGEO Drug Perturbation Signatures 1.0 null SP in perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18626 hippocampus (hippocampal formation)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.966585 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05182 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.933321 CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12643 GSE72895,GSE72896_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null GSE232631_0_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NEFM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2217 NCIH1373 DepMap CRISPR Gene Dependency 1.0 2.19817 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.985102 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49707 MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.914446 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_12187_OE_linc00520_SRP083129 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.47017 19621087-Table1a GeneSigDB Published Gene Signatures 1.0 null H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE200673,GSE200691_1_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42747 CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C8G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28151 BRCA1 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05882 GSE48812_9_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null GSE240645_3_v_2_u90926_mouse RummaGEO Gene Perturbation Signatures 1.0 null EIF3E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6001 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7153-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62312 Malignant tumor of pancreas_saliva_GSE14245 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.42116 r10 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67276 GSE158197_0_v_11_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZBTB7A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.879917 periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9676 NCI-H510A COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 FLT3 Kinase Library Tyrosine Kinome Atlas 1.0 96.5 r3 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22543 Myositis ossificans DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.192 TRKC Kinase Library Tyrosine Kinome Atlas 1.0 98.71 NDUFS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18255 GSE202744_1_v_3_toyocamycin_human RummaGEO Drug Perturbation Signatures -1.0 null PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR Rummagene Transcription Factor Associations 2026 1.0 null striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.921816 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MO-0226-SM-32QOL GTEx Tissue Sample Gene Expression Profiles 1.0 0.853832 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.505915 ITFG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08961 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1A_HNF1A Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EKVX CCLE Cell Line Gene CNV Profiles 1.0 2.14687 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23012 GSE118617,GSE118619_0_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null occipito-temporal gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.825324 r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.70439 r5 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92977 mRNA_GADD45A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44406 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.90229 POLR2A ENCODE Transcription Factor Targets 1.0 null CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19957 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42195 primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.81837 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null PMC12582692-medi-104-e45093-s001.xlsx-Table_S1-Table_S1_Genetic_instruments_of_plasma_proteins_for_MR_analysis_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29947 ZBTB7A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.02648 hsa-miR-1200 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 preisthmic tegmentum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44468 GSE206729_3_v_0_trps1_human RummaGEO Gene Perturbation Signatures -1.0 null m2 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2711 NFIC_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE188870,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null TCERG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95071 HSC1 DepMap CRISPR Gene Dependency 1.0 3.09368 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6U8-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1268b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.875824 GTEX-XPVG-1826-SM-4B64X GTEx Tissue Sample Gene Expression Profiles 1.0 0.943087 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.169 FAIM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12272 GATA2 ChEA Transcription Factor Targets 1.0 null Anterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28307 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19521 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null INCENP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57197 Prostate adenocarcinoma_PRAD_TCGA-CH-5761-11A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02088 LAMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09608 stomach BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959223 CAMA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.89003 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 20421987-TableS4 GeneSigDB Published Gene Signatures 1.0 null ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.21585 GSE210885_5_v_7_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null HNF4A ChEA Transcription Factor Targets 1.0 null H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null preisthmic midbrain tectum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.025 GTEX-OHPM-1426-SM-3TW8Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.936968 TUHR10TKB CCLE Cell Line Gene Expression Profiles -1.0 -1.45571 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11619 hsa-miR-4728-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE165122_0_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null BEST4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72096 GSE210655_1_v_4_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null dorsal part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05195 Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EPHB3 Kinase Library Tyrosine Kinome Atlas 1.0 96.5 HNF4G_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE171292_5_v_2_ehhadh_mouse RummaGEO Gene Perturbation Signatures 1.0 null EIF3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63153 KPNRTBM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.16856 LS1034 CCLE Cell Line Gene CNV Profiles -1.0 -1.44232 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null retroreuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.22623 GSE158197_2_v_10_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -2.47291 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE232631_5_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GOPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41087 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2 Rummagene Transcription Factor Associations 2026 1.0 null UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22892 H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWOO-1326-SM-48TCJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.840214 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null NCIH510 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 NCIH520 CCLE Cell Line Gene CNV Profiles 1.0 1.84089 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE193258,GSE193259_5_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.35291 Perturb_17681_KO_Kdm4a_SRP101992 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.81436 TBCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92253 Proximal segment cell_Fetal kidney_Human CellMarker Gene-Cell Type Associations 1.0 null CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null plasma membrane GO Cellular Component Annotations 2015 1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Perturb_4788_OE_Gadd45g_SRP315685 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.08586 central part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03127 mRNA_NANOG_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GSE216538_1_v_6_mrs2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.891021 Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08547 mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null SW1116 DepMap CRISPR Gene Dependency 1.0 2.60403 ECSCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05527 HARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20263 HNF4A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE115363_2_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE210655_1_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null mRNA_MEF2C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null amygdaloid complex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2395 Lung adenocarcinoma_LUAD_TCGA-05-4389-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12611713-Table2.xlsx-Sheet_1-Training_Database_AND_Validation_Database_NOT_Diabetes_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null Supramammillary nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01106 Posterior parietal association areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5453 MAX ENCODE Transcription Factor Targets 1.0 null TMEM134 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78036 FOS ENCODE Transcription Factor Targets 1.0 null GSE114284_4_v_3_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-UJMC-1326-SM-4IHLS GTEx Tissue Sample Gene Expression Profiles 1.0 0.909328 FU97 CCLE Cell Line Gene CNV Profiles -1.0 -1.50197 POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r11 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42747 periventricular stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62804 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973284 PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR Rummagene Transcription Factor Associations 2026 1.0 null OE19 CCLE Cell Line Gene Expression Profiles 1.0 1.43718 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62312 mantle zone of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42747 PMC5481429-41598_2017_4370_MOESM2_ESM.xls-SOM-cluster-genes_transcriptionally_related_to_DNAJC22_in_human_GRHL3 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4251 TargetScan Predicted Conserved microRNA Targets 1.0 0.248923 reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27356 18676831-Table1 GeneSigDB Published Gene Signatures 1.0 null orbital frontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37911 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63682 H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Lung transplant rejection_Trachea_GSE3418 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.16553 BECKER CCLE Cell Line Gene CNV Profiles 1.0 1.67645 GTEX-QDVJ-1426-SM-48U1Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.840127 GSE82032_3_v_1_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE239688_2_v_3_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null DHODH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01067 GSE210885_2_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null IZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.955039 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-12-HIVEP3_HIVEP3 Rummagene Transcription Factor Associations 2026 1.0 null FOXA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null ZNF281 ChEA Transcription Factor Targets 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-8395-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retrosplenial area, lateral agranular part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.103 GSE216538_5_v_6_mrs2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67494 CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.5428 NCIH650 DepMap CRISPR Gene Dependency 1.0 2.55331 USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESC_J1_UP_EARLY.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null H2BK12ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE98898_8_v_1_hoxa1_human RummaGEO Gene Perturbation Signatures -1.0 null PYCR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59462 Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null HEY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02037 GSE225901_0_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH1648 CCLE Cell Line Gene CNV Profiles -1.0 -3.21006 GTEX-XUZC-0126-SM-4BOO6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.84627 GSS CCLE Cell Line Gene Expression Profiles -1.0 -2.08824 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GALE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18238 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07763 ZR751 CCLE Cell Line Gene CNV Profiles -1.0 -1.50835 r7 part of the basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08939 Perturb_15450_OE_OVOL2_SRP026256 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 inner CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19834 PL45 CCLE Cell Line Gene CNV Profiles -1.0 -1.60316 PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8 Rummagene Transcription Factor Associations 2026 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42195 GSE227698_5_v_1_g0s2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE172016_2_v_1_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44468 bone marrow HPA Tissue Gene Expression Profiles -1.0 -1.27316 GSE246053_1_v_2_hnf4a_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15506 Brain Lower Grade Glioma_LGG_TCGA-HT-7902-01A-12R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r1 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15486 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47741 GSE157594_0_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE157960_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.867509 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5036_KD_Smarcc1_SRP221174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.05104 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.891021 RPMI8226 DepMap CRISPR Gene Dependency 1.0 4.62936 ZEB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE216538_0_v_4_mrs2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE210655_3_v_4_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null PPP1R37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15043 496100290_PCx_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.38128 RDH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02301 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23012 mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23755 GSE152432_6_v_0_zrsr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null VN(H5N1)_12hour_None_GSE37245 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.28832 ZEB1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32084 BC3C DepMap CRISPR Gene Dependency 1.0 3.23395 Fibroosseous pseudotumor of digits DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.749 GSE111035,GSE111040_10_v_9_plag1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2966-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76401 DDI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04298 superficial stratum of PrS (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44468 SPACA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28414 mRNA_SMAD7_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44468 GSE163862_2_v_3_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF Rummagene Transcription Factor Associations 2026 1.0 null Posterior parietal association areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20261 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KF-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Major island of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60398 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47465 PJA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30598 Striatum ventral region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58271 VMRCLCD CCLE Cell Line Gene Expression Profiles 1.0 1.99267 2313287 CCLE Cell Line Gene Expression Profiles 1.0 1.9546 POU5F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55Z-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4667_KO_Setd5_ERP110684 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.54869 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.69239 GSE199606_6_v_4_csf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE118077_7_v_2_sprr5_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Supplemental somatosensory area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08375 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.20464 hsa-miR-3647-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GSE136232,GSE136234_0_v_1_zpbp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null heart_6b HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 GSE149359_3_v_0_asap2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null rectum_8d HPA Tissue Sample Gene Expression Profiles 1.0 0.857734 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.97426 GSE173810_0_v_1_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OGFOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36065 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE229973_3_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08321 H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF596 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00015 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRKA Kinase Library Tyrosine Kinome Atlas 1.0 96.7 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881797 CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE202434,GSE202438_13_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null TM31 CCLE Cell Line Gene Expression Profiles -1.0 -2.47556 GSE237040_6_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null estradiol_mus musculus_gpl4134_gse23241 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE107505_0_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null intermediate part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59267 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-11A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92977 GSE85880,GSE85881_0_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.99905 GSE239844_11_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.68406 GSE91015_0_v_1_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16192 CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE202434,GSE202438_6_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Midbrain raphe nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62804 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.02447 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.23955 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21771 posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.14425 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32426 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.98824 496100610_TCx_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07927 primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.896183 H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37792 CDC5L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58768 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10228 superficial stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92977 H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null leucine-sensitive hypoglycemia of infancy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.735 fat_8a HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 hsa-miR-4324 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1 Rummagene Transcription Factor Associations 2026 1.0 null H4K91ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.30845 UQCRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25568 KLHL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04897 GSE57871_1_v_12_vorinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GSE111247_11_v_10_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null intermediate stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19469 Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03923 GSE237040_4_v_5_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Entorhinal area, lateral part, layer 2b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45597 GSE112714_2_v_0_ctnnb1_human RummaGEO Gene Perturbation Signatures 1.0 null SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27651 GSE139455_0_v_6_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97211 GSE218819_2_v_1_kdm5b_human RummaGEO Gene Perturbation Signatures 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fusiform gyrus, left, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.947352 GSE251992_1_v_0_saracatinib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7156-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB361 DepMap CRISPR Gene Dependency 1.0 4.27993 Dentin caries DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.365 OVKATE CCLE Cell Line Gene Expression Profiles 1.0 1.85474 lymphnode_4b HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QCQG-0526-SM-48U2A GTEx Tissue Sample Gene Expression Profiles 1.0 1.04638 HSPA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55666 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.944298 FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30924 BTBD17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55808 GSE198434_1_v_0_aspirin_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-4319 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 Temporal association areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.69423 GSE96641_3_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE246053_4_v_2_hnf4a_mouse RummaGEO Gene Perturbation Signatures -1.0 null outer CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08863 caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21116 CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.33018 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5259899-13287_2016_455_MOESM2_ESM.xlsx-Down-regulated-Supplementary_Table_S2_Down-reguated_genes_expression_in_MESP1_negative_cells_MESP1 Rummagene Transcription Factor Associations 2026 1.0 null PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-OVOL2_OVOL2 Rummagene Transcription Factor Associations 2026 1.0 null CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959712 IALM CCLE Cell Line Gene CNV Profiles 1.0 1.42884 GSE182680,GSE182683_0_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parasubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21493 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4396-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2BK20ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BT16 DepMap CRISPR Gene Dependency 1.0 4.36934 GSE174701_1_v_0_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null ZNHIT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2455 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE115542_5_v_1_digoxin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-POMQ-0826-SM-3P61H GTEx Tissue Sample Gene Expression Profiles 1.0 0.883767 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-CA-04-2009(H1N1)MA_Day1_22532695_GSE36328 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.23527 cell part GO Cellular Component Annotations 2015 1.0 null QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.834397 p3 portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15486 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null NCIH522 DepMap CRISPR Gene Dependency 1.0 2.04872 GTEX-XUZC-1326-SM-4BRV2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07182 ADGRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8653 GTEX-P4QT-1426-SM-3NMCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.985912 GSE135705_5_v_3_corticosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE80537_3_v_2_adhfe1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE199255,GSE199356_4_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.25066 hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15613 Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3646 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE217405_3_v_2_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22892 GTEX-XUZC-0726-SM-4BOPH GTEx Tissue Sample Gene Expression Profiles 1.0 0.967743 MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE120413,GSE120447_3_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null tretinoin_mus musculus_gpl1261_gds4294 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null WDR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9868 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0092 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5026 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null alar part of peduncular hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.44967 CORL105 CCLE Cell Line Gene CNV Profiles -1.0 -1.62567 GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures 1.0 null p1 portion of the paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58271 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10794847-mmc6.xlsx-PIAS1_KD_up-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR Rummagene Transcription Factor Associations 2026 1.0 null NOB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.08746 MPI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27671 GSE57871_1_v_9_vorinostat_human RummaGEO Drug Perturbation Signatures 1.0 null DMS153 CCLE Cell Line Gene CNV Profiles 1.0 1.46718 LUDLU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.39222 PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null EXOSC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05757 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.87006 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23012 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A66X-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null 20860821-TableS5 GeneSigDB Published Gene Signatures 1.0 null spleen_3b HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 H2AK5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE198165,GSE198166_5_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null ventral tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19469 UOK101 CCLE Cell Line Gene Expression Profiles -1.0 -1.79036 GTEX-Q734-1126-SM-48TZY GTEx Tissue Sample Gene Expression Profiles 1.0 0.941024 GSE205730,GSE205731_2_v_3_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null CDK19_knockdown_164_GSE38061 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.62154 superficial stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09371 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.42437 GSE107505_3_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null superior parietal lobule, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.971639 GSE107505_1_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE48812_0_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null m2 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.025 GSE205163,GSE205164_9_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE240645_1_v_0_u90926_mouse RummaGEO Gene Perturbation Signatures -1.0 null lateral IC periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19469 MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHH2 DepMap CRISPR Gene Dependency 1.0 5.45186 mantle zone of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22543 Entorhinal area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25035 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null G43417UB GlyGen Glycosylated Proteins 1.0 null planum polare, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54723 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.97426 ZFP281-18757296-E14-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null rostromedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16412 GSE220520_3_v_4_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null POU5F1 ENCODE Transcription Factor Targets 1.0 null H3K27me3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute pancreatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.169 TAL1 ENCODE Transcription Factor Targets 1.0 null GSE214382,GSE214383_6_v_2_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PLZ5-1126-SM-3P613 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01602 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hypochondriasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.143 testis HPA Tissue Protein Expression Profiles 1.0 0.85799 ATF2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TALL1 CCLE Cell Line Gene Expression Profiles -1.0 -1.76039 Primary motor area, Layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3302 GTEX-S95S-0826-SM-4B64N GTEx Tissue Sample Gene Expression Profiles 1.0 0.878001 GSE211241_1_v_0_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNU81 CCLE Cell Line Gene Expression Profiles 1.0 1.41021 Central medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76758 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.87273 Endocrine system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.169 core of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82246 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33419 CTCF_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3674 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29544 ventral posterior parvicellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95188 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Olfactory tubercle, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56036 middle temporal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.866394 CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6477-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51894 Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_1_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null r1 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70645 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RALA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5648 GTEX-QCQG-1626-SM-48U26 GTEx Tissue Sample Gene Expression Profiles 1.0 0.938416 GSE153189_1_v_3_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22892 GSE232631_4_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE193177_1_v_2_st266_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MERO83 DepMap CRISPR Gene Dependency 1.0 2.20652 SP1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TML8-1326-SM-4DXTO GTEx Tissue Sample Gene Expression Profiles 1.0 0.995788 GSE221327_6_v_11_clpp_human RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral (non-cerebellar) part of isA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17399 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL29 DepMap CRISPR Gene Dependency 1.0 2.87922 RAD21_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE178227_1_v_0_tet1_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH810 CCLE Cell Line Gene Expression Profiles 1.0 1.55077 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoplasmic part GO Cellular Component Annotations 2015 1.0 null MMP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06086 VPS28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39052 GSE152937_12_v_7_slc16a13_mouse RummaGEO Gene Perturbation Signatures 1.0 null Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38073 FOXA1 ENCODE Transcription Factor Targets 1.0 null POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975476 GSE145215_2_v_1_krt13_mouse RummaGEO Gene Perturbation Signatures 1.0 null reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.7892 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26884 GSE92364_0_v_5_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54394 Gastrointestinal Symptom DisGeNET Gene-Phenotype Associations 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null NYAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51687 SOX2-20726797-SW620-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_12063_KO_Stat5a/Stat5b_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 PRIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52077 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62312 hsa-miR-1268 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 inner SZ in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05047 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE241701_2_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null CYFIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20179 GSE88819_5_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.999975 Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null GSE114284_4_v_0_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.39887 H3K79me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62731 WPE1NA22 DepMap CRISPR Gene Dependency 1.0 2.80703 LMO2 ChEA Transcription Factor Targets 1.0 null presubiculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44468 mantle zone of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23187 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBM22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36586 PMC4060771-170289.f1.pdf-108-BARX2_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null GSE145249_1_v_3_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XMK1-1726-SM-4B64Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.90661 isthmus proper Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20488 Anterior cingulate area, ventral part, 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0089 Olfactory tubercle Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12816 PMC9306206-12915_2022_1367_MOESM8_ESM.xlsx-Table_S9_-_JIP-Gene_SMAD4 Rummagene Transcription Factor Associations 2026 1.0 null HSD17B7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14441 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-5305-01A-01R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205163,GSE205164_1_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE199255,GSE199356_6_v_5_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null TWIST1_01_252 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.33928 GSE120413,GSE120447_0_v_5_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE130437_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null RTRAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86635 Fields of Forel Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35863 VMRCLCD DepMap CRISPR Gene Dependency 1.0 4.26944 Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, barrel field, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90234 GSE236502_2_v_3_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9676 GTEX-S4UY-0826-SM-4AD4Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.923645 RCHACV DepMap CRISPR Gene Dependency 1.0 2.27332 GSE122215,GSE122217_0_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-510 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.857768 MM160113 DepMap CRISPR Gene Dependency 1.0 3.99244 FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8264-01B-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20855 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4732-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.17031 layer 6b of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89086 GSE157594_0_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K14ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null centromedian nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1233 H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4684-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 peduncular part of dorsomedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21493 TLNRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27523 MAPKAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40465 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1284 GTEX-X5EB-1626-SM-4E3IV GTEx Tissue Sample Gene Expression Profiles 1.0 0.826618 GSE158197_6_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15274 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11318 SETDB1 ENCODE Transcription Factor Targets 1.0 null MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.891021 ZNF836 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00531 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.43096 Pancreatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.169 H3K18ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8174-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superior parietal lobule, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14173 8MGBA CCLE Cell Line Gene CNV Profiles 1.0 1.47912 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05182 GSE95685_2_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE133927_1_v_0_meox1_human RummaGEO Gene Perturbation Signatures -1.0 null superficial mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11955 GTEX-S4P3-1226-SM-4AD4Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.890509 GSE146074_9_v_7_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null UTP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31829 GSE148262,GSE150691_1_v_0_hdlbp_human RummaGEO Gene Perturbation Signatures -1.0 null GSE248858_6_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE85880,GSE85881_4_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null membrane GO Cellular Component Annotations 2015 1.0 null GSE193993_1_v_7_sstr2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OOBJ-1526-SM-3NB1Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.06216 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.891021 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09418 GSE200673,GSE200691_1_v_3_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOXA2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE154350_1_v_0_ascl2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE112860_3_v_2_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-661 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 INTS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15183 GSE148510_1_v_2_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null RIPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36873 GTEX-RWS6-0926-SM-47JXE GTEx Tissue Sample Gene Expression Profiles 1.0 0.883952 r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01106 CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PHF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25228 GALM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10454 HCC1195 CCLE Cell Line Gene CNV Profiles 1.0 1.79267 H3K79me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MDAMB175VII CCLE Cell Line Gene CNV Profiles -1.0 -1.73247 GSE234289_5_v_2_rfx6_human RummaGEO Gene Perturbation Signatures -1.0 null blastocysts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 SKNBE2 CCLE Cell Line Gene CNV Profiles -1.0 -1.78014 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01121 GTEX-TKQ2-1326-SM-4DXT9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879731 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX21_SOX21 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE239688_4_v_0_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_11068_KO_Dnajb9_SRP097622 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.54951 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30532 GTEX-WFG7-1326-SM-4LMK1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.834023 GSE163862_0_v_3_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCIH854 CCLE Cell Line Gene Expression Profiles 1.0 1.36459 MOLP8 CCLE Cell Line Gene Expression Profiles -1.0 -1.47745 GTEX-XUZC-1426-SM-4BRV3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.884201 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.57463 HNF4A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-0826-SM-4AD5E GTEx Tissue Sample Gene Expression Profiles 1.0 0.887239 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null medial part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00973 TMEM249 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1175 r9 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9786 HT-144 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01121 bonemarrow_6c HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 STAT3 MotifMap Predicted Transcription Factor Targets 1.0 null mantle zone of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01018 SNU387 DepMap CRISPR Gene Dependency 1.0 2.46497 orbital frontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04349 layer 6 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72484 GTEX-XUJ4-2026-SM-4BOOW GTEx Tissue Sample Gene Expression Profiles 1.0 0.997655 SOX5 JASPAR Predicted Transcription Factor Targets 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null GSE199255,GSE199356_3_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53 Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE43041,GSE43044_0_v_1_ldb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06558 BOKU DepMap CRISPR Gene Dependency 1.0 3.52674 cervix, uterine HPA Tissue Protein Expression Profiles 1.0 0.85799 Primary somatosensory area, lower limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41714 PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF Rummagene Transcription Factor Associations 2026 1.0 null PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR Rummagene Transcription Factor Associations 2026 1.0 null lymphnode_5b HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 93T449 DepMap CRISPR Gene Dependency 1.0 2.06252 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null spleen_3a HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28078 medial part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05282 mRNA_NANOG_16767105 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GSE169155_3_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null NPM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14651 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.889186 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE174701_4_v_0_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WFON-1426-SM-4LVMT GTEx Tissue Sample Gene Expression Profiles 1.0 1.02803 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null temporal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42388 TIMM8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32584 Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE248858_1_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE114284_1_v_5_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OXRK-1726-SM-3NB16 GTEx Tissue Sample Gene Expression Profiles 1.0 0.89137 hsa-miR-5096 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 hsa-miR-1285 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE140997_10_v_1_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.36544 GSE244072_10_v_9_tfeb_mouse RummaGEO Gene Perturbation Signatures 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900365 NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12298 orbital frontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.879104 superficial stratum of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22543 TTC549 DepMap CRISPR Gene Dependency 1.0 3.01812 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE258991_1_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE96641_5_v_0_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.958983 ChIP_TCF3_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UPIC-1726-SM-4IHKG GTEx Tissue Sample Gene Expression Profiles 1.0 0.954741 GSE205163,GSE205164_3_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null WHSC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null medial amygdala, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01532 hsa-miR-3689c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Submedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38051 EW8 DepMap CRISPR Gene Dependency 1.0 2.75531 CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null superior parietal lobule, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.950247 KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.39883 GSE165122_2_v_1_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.922474 SNU-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39736 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE164508_1_v_0_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE162739_8_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.829421 r10 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03206 isthmic basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12816 GSE211286_1_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.859035 Perturb_16526_KO_Ahrr_SRP318414 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.43982 CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE172016_2_v_0_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null TEAD1 JASPAR Predicted Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREBBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14972_KO_Max_SRP225905 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.75087 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE147876,GSE147877_2_v_8_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null LXF289 CCLE Cell Line Gene CNV Profiles 1.0 1.64876 GSE112174_5_v_7_runx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Multifocal dystonia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.272 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.64378 fat_a.V1 HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.39396 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01121 GSE247775_1_v_0_tmprss2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31898 GSE199606_1_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.72809 HSOS1 DepMap CRISPR Gene Dependency 1.0 2.59457 GSE120413,GSE120447_4_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.85569 primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.982744 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.53201 CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH526 CCLE Cell Line Gene CNV Profiles 1.0 1.72637 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE188721_3_v_4_mesp1_human RummaGEO Gene Perturbation Signatures 1.0 null STAT3-1855785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null vagina HPA Tissue Protein Expression Profiles 1.0 1.48737 Primary somatosensory area, barrel field, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02348 GSE237040_4_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE158197_0_v_4_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE220520_1_v_7_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55823 MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49707 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00967 SP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16953 H3K27me3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.82868 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04671 GSE111035,GSE111040_8_v_5_plag1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE229973_4_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.63595 GTEX-OHPK-1526-SM-3MJGM GTEx Tissue Sample Gene Expression Profiles 1.0 0.85111 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15863 GSE127790_11_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKRC20 CCLE Cell Line Gene Expression Profiles -1.0 -1.62078 FXR MotifMap Predicted Transcription Factor Targets 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15611 GSE164757,GSE164759_1_v_0_trametinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7840-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100459_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.30911 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03012 H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8281-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.854821 GSE198165,GSE198166_0_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE217405_0_v_1_osimertinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20062 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34715 kidney BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.22829 hsa-miR-4486 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25136 EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26471 GABPA ENCODE Transcription Factor Targets 1.0 null ChIP_H3K36me3_18692474_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Secondary motor area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05844 HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null GSE199255,GSE199356_4_v_2_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null ventral tegmental area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.56559 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10529 Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE200839,GSE233826_5_v_4_tnrc18_human RummaGEO Gene Perturbation Signatures 1.0 null GSE125862_2_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2 Rummagene Transcription Factor Associations 2026 1.0 null GSE199606_3_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCIH1876 CCLE Cell Line Gene CNV Profiles 1.0 1.46651 GSE205163,GSE205164_3_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08321 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_17541_KD_MEOX1_SRP213607 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_7_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE176008_7_v_2_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53631 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16412 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.15962 PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR Rummagene Transcription Factor Associations 2026 1.0 null Arsenic CTD Gene-Chemical Interactions 1.0 null H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP4 ENCODE Transcription Factor Targets 1.0 null Perturb_17700_KO|KD_Pds5a|Pds5b_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OAW28 CCLE Cell Line Gene Expression Profiles 1.0 1.42391 icSARA deltaORF6_3Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.97679 hsa-miR-4722-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 VSIG10L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63088 PCNX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29914 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF4A ENCODE Transcription Factor Targets 1.0 null GTEX-Q2AH-1126-SM-48TZM GTEx Tissue Sample Gene Expression Profiles 1.0 0.857286 CSFR Kinase Library Tyrosine Kinome Atlas 1.0 95.21 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.8422 Olfactory tubercle, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11049 mRNA_T_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null MCM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42239 CTCF ENCODE Transcription Factor Targets 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null MYO19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15472 NCIH2081 CCLE Cell Line Gene CNV Profiles 1.0 1.43374 DMS454 CCLE Cell Line Gene Expression Profiles 1.0 2.63501 Secondary motor area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67873 H2BK5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6370-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NUP93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31976 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-125b TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.859908 Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49691 SNU719 CCLE Cell Line Gene Expression Profiles 1.0 1.38007 MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.30845 FOXA1_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_id_AR Rummagene Transcription Factor Associations 2026 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13 Rummagene Transcription Factor Associations 2026 1.0 null r10 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24618 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38051 LS513 CCLE Cell Line Gene Expression Profiles 1.0 1.53119 Prelimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08547 H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE199255,GSE199356_3_v_5_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE205163,GSE205164_2_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null ZEB1 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.6037 GSE111035,GSE111040_8_v_9_plag1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE130246_2_v_3_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE48812_9_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of m2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25886 MOLM14 DepMap CRISPR Gene Dependency 1.0 4.53845 Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO668 CCLE Cell Line Gene CNV Profiles 1.0 1.80277 GTEX-XQ8I-2026-SM-4BOOL GTEx Tissue Sample Gene Expression Profiles 1.0 0.843665 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ectorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10164 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE147366_1_v_2_med13_human RummaGEO Gene Perturbation Signatures -1.0 null GSE144500_7_v_6_ventx_human RummaGEO Gene Perturbation Signatures 1.0 null KMS12BM CCLE Cell Line Gene CNV Profiles -1.0 -1.45067 Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92977 GSE149123,GSE149128_1_v_0_cdk7_mouse RummaGEO Gene Perturbation Signatures -1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null amygdaloid complex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.947043 TFAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30863 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4459 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.988068 GSE152432_3_v_0_zrsr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ID3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69756 NCIH209 CCLE Cell Line Gene CNV Profiles 1.0 1.52106 POU5F1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205163,GSE205164_3_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWN1-1426-SM-48TDF GTEx Tissue Sample Gene Expression Profiles 1.0 0.974954 GSE210655_3_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null EGR1 ChEA Transcription Factor Targets 1.0 null HOXD9_01_70 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.64 H2BK120ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE111035,GSE111040_3_v_13_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.81152 FOXO1 ChEA Transcription Factor Targets 1.0 null GSE144838_7_v_8_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE199606_6_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W7-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_short_name_AR Rummagene Transcription Factor Associations 2026 1.0 null MGAT4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01426 superficial stratum of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42747 GTEX-XBED-1526-SM-4AT5W GTEx Tissue Sample Gene Expression Profiles 1.0 0.887492 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.83926 GSE210655_1_v_5_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Perturb_5161_KO_Trp53_SRP048945 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.54571 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pyramidal layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.914144 peduncular paraventricular area of PHyA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12816 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.50064 EXOSC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23789 layer 5 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32167 PRKCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49644 PMC12358297-41388_2025_3481_MOESM3_ESM.xlsx-S9_ASCL1-regulated_genes-Unnamed_1_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null NCCLMS1C1 DepMap CRISPR Gene Dependency 1.0 7.72124 HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null GSE144115_2_v_3_stag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null EIF3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11873 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RD-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A5C7-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202434,GSE202438_10_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null 496100358_HIP_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.83197 subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.875226 H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FAM32A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21502 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2784 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02474 GSE144919,GSE145177_1_v_0_dazl_mouse RummaGEO Gene Perturbation Signatures 1.0 null Ventral posterolateral nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25868 GSE157049,GSE157051_6_v_1_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4736 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.33745 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5192-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE157594_5_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null superior rostral gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02712 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.494 GSE144838_1_v_8_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3664-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34865 intermediate part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15407 ESR1-22446102-UTERI-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.98408 MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null dorsomedial part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9676 GSE89729_0_v_1_ppard_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_18610_KO_Btnl2_SRP324170 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.42776 RRP7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41356 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10942 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18944 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6776-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 1-cell stage cell (Blastomere)_Embryo_Human CellMarker Gene-Cell Type Associations 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null intracellular organelle GO Cellular Component Annotations 2015 1.0 null GSE216538_0_v_2_mrs2_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01406 GSE151412_2_v_1_sorafenib_human RummaGEO Drug Perturbation Signatures -1.0 null EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null mRNA_MSC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE248858_6_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null outer SZ in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35412 GSE199092_1_v_0_ddx5_human RummaGEO Gene Perturbation Signatures 1.0 null CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.30705 hsa-miR-4434 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04868 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.994624 PANC1005 CCLE Cell Line Gene CNV Profiles -1.0 -1.48054 HCC1833 CCLE Cell Line Gene Expression Profiles 1.0 3.40795 GSE85880,GSE85881_0_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100373_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.16943 Perturb_17699_KO_Pds5a_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.5327 SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE226452_1_v_0_imiquimod_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55G-1226-SM-48FDC GTEx Tissue Sample Gene Expression Profiles 1.0 1.04768 skeletalmuscle_d HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.48476 GSE60837_0_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3689a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE150134_1_v_0_fluorouracil_human RummaGEO Drug Perturbation Signatures 1.0 null fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13601 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34715 short insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.922521 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.873397 periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06992 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35679 SUPT1 DepMap CRISPR Gene Dependency 1.0 2.22596 amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.974674 IARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03834 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null mantle zone of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11049 Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100462_PCx_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.66552 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.93614 Perturb_5213_KO_Terc_SRP156128 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAB39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02031 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.941372 Lung squamous cell carcinoma_LUSC_TCGA-66-2778-01A-02R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUCLG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69281 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1B_HNF1B Rummagene Transcription Factor Associations 2026 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42195 RPS23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15885 Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null GSE88819_5_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.841204 Lung squamous cell carcinoma_LUSC_TCGA-34-5240-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.11402 GSE202434,GSE202438_4_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE217405_0_v_1_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE226439,GSE226441_6_v_2_hnf4g_human RummaGEO Gene Perturbation Signatures -1.0 null VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11981 GTEX-WFG7-1526-SM-4LVMG GTEx Tissue Sample Gene Expression Profiles 1.0 0.969158 GSE153189_1_v_0_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04531 Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78018 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.97535 H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null BNC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21861 TF1 CCLE Cell Line Gene CNV Profiles 1.0 1.46044 Entorhinal area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32357 primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08886 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11975397-JPN-240126-at-1.pdf-23-ZNF557_ZNF557 Rummagene Transcription Factor Associations 2026 1.0 null ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.92172 NCIH2029 CCLE Cell Line Gene CNV Profiles 1.0 2.00388 Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.23244 ventral posterior medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40071 Fetal Death CTD Gene-Disease Associations 1.0 1.24874 GSE118617,GSE118619_2_v_3_foxp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NH6 CCLE Cell Line Gene CNV Profiles -1.0 -1.9275 mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null mantle zone of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05324 TRIM24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20002 GSE205163,GSE205164_9_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null GSE202434,GSE202438_13_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.826618 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE237040_0_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE145215_0_v_3_krt13_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE128730_4_v_2_neratinib_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6WD-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null m1 part of parabrachialis pigmentosus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.137 GSE48812_4_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67384 frontal operculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04064 GSE104022_3_v_7_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE235587_2_v_0_mitoxantrone_human RummaGEO Drug Perturbation Signatures 1.0 null JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.50069 Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158815_1_v_3_trib1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE202434,GSE202438_6_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null TGBC18TKB DepMap CRISPR Gene Dependency 1.0 2.56399 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r6 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14395 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05182 GSE158815_5_v_3_trib1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE151412_2_v_3_sorafenib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 1 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42747 r11 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42747 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49707 amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0008 Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PX3G-1526-SM-48U11 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85903 GSE244072_10_v_8_tfeb_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mesomere 2 (preisthmus or caudal midbrain) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73296 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Entorhinal area, lateral part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26949 GSE165122_2_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Midbrain reticular nucleus, retrorubral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49805 DMRT1 ChEA Transcription Factor Targets 1.0 null ELK4 JASPAR Predicted Transcription Factor Targets 1.0 null GSE206729_3_v_1_trps1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE102675_3_v_0_atf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54592 GSE152937_6_v_5_slc16a13_mouse RummaGEO Gene Perturbation Signatures -1.0 null ITK_defectivemutant_125_GSE28200 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.44168 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE157555,GSE157556_4_v_7_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4510-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNUC1 DepMap CRISPR Gene Dependency 1.0 2.86253 GSE161864,GSE161866_1_v_3_ror2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE205163,GSE205164_5_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.32283 GSE136622_0_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary motor-sensory cortex (samples)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.975435 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null PMC3348545-NIHMS263168-supplement-3.pdf-41-ZNF691_ZNF691 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE122215,GSE122217_5_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE182680,GSE182683_5_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.48637 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0755 MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE153189_2_v_3_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCI-H748 COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 RI1 DepMap CRISPR Gene Dependency 1.0 3.33409 CHAGOK1 CCLE Cell Line Gene CNV Profiles 1.0 1.6566 recycling endosome GO Cellular Component Annotations 2015 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68273 LI7 CCLE Cell Line Gene Expression Profiles -1.0 -1.66619 upper dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42747 GSE144115_1_v_3_stag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null AKT2_knockdown_44_GSE12291 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.76594 intracellular part GO Cellular Component Annotations 2015 1.0 null hsa-miR-612 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 intermediate stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09028 Perturb_3846_KD_CABLES2_SRP166266 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.58489 GSE168602,GSE168604_2_v_1_selumetinib_human RummaGEO Drug Perturbation Signatures 1.0 null C5orf24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5366 GTEX-XXEK-1026-SM-4BRUW GTEx Tissue Sample Gene Expression Profiles 1.0 0.881541 OXNAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00225 PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE157594_3_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.914324 interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20646 GSE210842_3_v_1_hnf4a_mouse RummaGEO Gene Perturbation Signatures -1.0 null EGR1 ENCODE Transcription Factor Targets 1.0 null TYKNU CCLE Cell Line Gene CNV Profiles 1.0 2.21255 mantle zone of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03206 r10 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22543 Entorhinal area, lateral part, layer 2a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49953 CL34 CCLE Cell Line Gene Expression Profiles 1.0 1.45389 H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null temporal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.97863 posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.965755 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34715 Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null L428 DepMap CRISPR Gene Dependency 1.0 2.59328 RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7596-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_17701_KO|KD_Pds5a|Stag1_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 COLO668 CCLE Cell Line Gene Expression Profiles 1.0 2.416 SLC1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49839 GSE157594_6_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ALKBH5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04126 Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE120413,GSE120447_4_v_5_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100361_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.37174 mantle zone of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12508 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00714 Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44406 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.02877 GSE86507,GSE86509_7_v_10_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null SUPT20H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34696 GTEX-W5WG-2426-SM-4LMI6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.946454 inner CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.48004 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16526 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4787_KD_Akap8_SRP075747 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.9923 GSE146074_0_v_7_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE158632_2_v_5_oxyquinoline_human RummaGEO Drug Perturbation Signatures -1.0 null SNU520 CCLE Cell Line Gene Expression Profiles 1.0 2.11468 GSE57871_11_v_12_vorinostat_human RummaGEO Drug Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38253 VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49508 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08321 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A770-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null muscle GTEx Tissue Gene Expression Profiles -1.0 -0.876419 CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral amygdaloid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13809 brain_3c HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21406 caudal interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.025 Branch retinal artery occlusion DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.266 DNALI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3618 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2207 YH13 CCLE Cell Line Gene Expression Profiles -1.0 -1.64586 MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17593 Primary somatosensory area, barrel field Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18346 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PY-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34471 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.67019 GTEX-UJHI-1126-SM-4IHLN GTEx Tissue Sample Gene Expression Profiles 1.0 0.990164 EP300_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, lower limb, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45648 GSE143790_0_v_1_bcl9_human RummaGEO Gene Perturbation Signatures 1.0 null GSE168587,GSE168752_3_v_1_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28007 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.87406 FOXA1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE206729_4_v_1_trps1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null GSE176008_0_v_2_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null superior parietal lobule, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.870036 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59107 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24783 PPP2R5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1455 GSE232631_0_v_2_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.62201 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8216-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93713 Primary motor area, Layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25543 GSE129465_3_v_2_phf6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-0626-SM-4DM6H GTEx Tissue Sample Gene Expression Profiles 1.0 0.855904 rectum HPA Tissue Protein Expression Profiles 1.0 1.48737 GSE96641_1_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05682 STOM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33673 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PDHA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13921 CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE138019_4_v_6_nudt12_mouse RummaGEO Gene Perturbation Signatures 1.0 null TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE74528_0_v_1_trex2_mouse RummaGEO Gene Perturbation Signatures 1.0 null FGFR1_activemutant_58_GSE17916 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.84284 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null early endosome GO Cellular Component Annotations 2015 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null EP300_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CNTROB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44938 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZEB1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GSE200839,GSE233826_2_v_0_tnrc18_human RummaGEO Gene Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.832182 SP1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 15860665-Table1 GeneSigDB Published Gene Signatures 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-0926-SM-48FD1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.963339 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33601 EGR1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7SF-1926-SM-4AT5B GTEx Tissue Sample Gene Expression Profiles 1.0 0.956385 GSE214212_2_v_0_chd6_human RummaGEO Gene Perturbation Signatures 1.0 null medial part of r4B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25886 hsa-miR-3150a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 mantle zone of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34991 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.56632 PCNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38161 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.867378 BRCA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF12_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreas disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.169 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01197 GSE180185_9_v_5_setbp1_human RummaGEO Gene Perturbation Signatures 1.0 null KMRC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.79309 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null KDM4A ENCODE Transcription Factor Targets 1.0 null mantle zone of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20488 496100310_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.46346 TCF12 ENCODE Transcription Factor Targets 1.0 null intermediate stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76239 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U4B1-1126-SM-4DXV3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.950503 GSE139455_0_v_3_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null TERT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06228 Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59321 GSE186660_2_v_1_nicotine_mouse RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01106 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null heart_6a HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3187-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.92709 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-1426-SM-3NB1O GTEx Tissue Sample Gene Expression Profiles 1.0 0.850719 GSE157894_2_v_3_cystine_human RummaGEO Drug Perturbation Signatures 1.0 null Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE113817_0_v_1_bach1_human RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r1Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70645 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20261 MYC ENCODE Transcription Factor Targets 1.0 null GTEX-PLZ6-0926-SM-3P5ZQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.952484 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09761 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-PK-A5HA-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICR10 DepMap CRISPR Gene Dependency 1.0 2.11275 skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EPHA2 Kinase Library Tyrosine Kinome Atlas 1.0 96.83 Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.18451 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TRIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47318 lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.84138 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.962232 RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5034_KD_Smarcc1_SRP221174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -17.2321 RBBP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0723 GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ADNP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03797 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11579 ChIP_STAT3_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ventral reuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36398 cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00601 EZH2 ENCODE Transcription Factor Targets 1.0 null GSE140997_10_v_7_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null bonemarrow_6b HPA Tissue Sample Gene Expression Profiles -1.0 -0.88001 hsa-miR-4284 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null NCIH1435 CCLE Cell Line Gene Expression Profiles 1.0 1.77583 BACH1 ENCODE Transcription Factor Targets 1.0 null ECGI10 CCLE Cell Line Gene CNV Profiles -1.0 -1.36246 GSE202434,GSE202438_4_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44468 E2F4 ENCODE Transcription Factor Targets 1.0 null Diabetic Neuropathy_Sciatic Nerve_GSE11343 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.3725 GSE122215,GSE122217_5_v_2_peg10_mouse RummaGEO Gene Perturbation Signatures 1.0 null UPCISCC040 DepMap CRISPR Gene Dependency 1.0 3.14467 inner SZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.867796 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE199255,GSE199356_6_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE174701_5_v_6_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null Supplemental somatosensory area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.03733 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5261-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCI30 DepMap CRISPR Gene Dependency 1.0 2.22188 amygdaloid complex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.74345 GSE192870_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null POM121C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03672 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49453 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null NFIC JASPAR Predicted Transcription Factor Targets 1.0 null H3K79me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-S341-0626-SM-4AD5T GTEx Tissue Sample Gene Expression Profiles 1.0 0.894983 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32009 496100458_FWM_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.48207 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44406 Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95633 GSE248858_4_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null TKKK DepMap CRISPR Gene Dependency 1.0 3.22294 JHH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24281 Rectal benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.267 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null CES3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07886 ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41066 posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.869245 Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE115363_2_v_0_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-3619-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE87412,GSE92423_2_v_1_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.91872 PCNX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6103 CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.826617 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868511 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.842548 PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Myofascial pain syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.133 RH4 DepMap CRISPR Gene Dependency 1.0 2.23081 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5974 POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null core of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11049 TRKB Kinase Library Tyrosine Kinome Atlas 1.0 96.59 KMS18 CCLE Cell Line Gene Expression Profiles -1.0 -1.59027 GSE168596_2_v_3_adiponectin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE206729_5_v_0_trps1_human RummaGEO Gene Perturbation Signatures -1.0 null CORL24 CCLE Cell Line Gene CNV Profiles 1.0 2.31103 Perturb_14557_OE_ZEB1_SRP051606 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.20626 GSE150072,GSE169209_6_v_9_qser1_human RummaGEO Gene Perturbation Signatures 1.0 null p2 portion of the parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.137 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08679