association	dataset	threshold value	standardized value
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06881
SNRPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56577
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.428264
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49006
ZNF398	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13524
abnormal immunoglobulin level	GWASdb SNP-Phenotype Associations	1.0	0.525969
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72621
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92941
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55566
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953243
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55452
Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55715
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
NR6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.15296
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06931
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30356
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862556
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839717
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22966
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15163
SCH	DepMap CRISPR Gene Dependency	1.0	2.13531
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97083
AHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73785
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30561
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
STK11IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83394
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98811
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12876
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66262
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21718
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59318
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cholesterol	dbGAP Gene-Trait Associations	1.0	0.165039
GATA3	ENCODE Transcription Factor Targets	1.0	null
DPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69331
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30422
Autosomal recessive nonsyndromic deafness 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
SOX2	ChEA Transcription Factor Targets	1.0	null
KIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91674
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98235
TMEM184B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17871
REST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84617
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0153
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
EMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79507
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11042
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04531
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.066566
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ET-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34756
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
maturity-onset diabetes of the young type 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13741
PSENEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0363
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47324
GLB1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94682
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30306
NCIH660	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96076
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14117
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44515
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
JVM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55633
MPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2799
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31667
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42666
CCNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67065
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85115
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34981
auditory system disease	GWASdb SNP-Disease Associations	1.0	0.664902
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11493
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42053
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15844
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64089
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52496
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830475
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.48805
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03569
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.056118
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07149
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CLINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78567
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0526-SM-3MJHN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953025
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17906
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86714
TMEM209	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1705
WWTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19063
SERP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82434
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	2.03101
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21053
TMEM63B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6275
STAT3	ChEA Transcription Factor Targets	1.0	null
NCIH1355	CCLE Cell Line Gene Expression Profiles	1.0	1.82881
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54078
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
OV90	Achilles Cell Line Gene Essentiality Profiles	1.0	1.1445
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45127
CH157MN	DepMap CRISPR Gene Dependency	1.0	2.18153
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
MOGGUVW	DepMap CRISPR Gene Dependency	1.0	9.94544
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.265213
GOLM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5431
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73917
ARMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20539
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11811
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13271
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58713
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.093544
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848264
RWDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11247
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31594
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74553
ABI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82867
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929141
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.782
IRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17794
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76513
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75732
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6222
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976169
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66974
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7XC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38159
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61849
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40177
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970344
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32381
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.29865
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46804
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.35384
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66585
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92262
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04478
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61659
NANOGP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52743
COGN278	DepMap CRISPR Gene Dependency	1.0	3.33868
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00926
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91493
CPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6794
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94589
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06578
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869348
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92161
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46946
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21654
MPZL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71229
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27907
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60224
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49261
HSD11B1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00463
SEMA6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41772
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.98139
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05018
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878088
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72527
DENR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43861
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86281
22RV1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09923
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16578
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44639
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37724
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
AMER1_OE_GDS4802_549_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TUG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72668
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67775
GSE204784,GSE204787_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1581	CCLE Cell Line Gene Expression Profiles	1.0	1.51684
YY1	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R7-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0682
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41659
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07054
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.05325
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929141
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3758
FGFR3_KD_GDS4454_79_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04398
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
HMGCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34028
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57921
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884448
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33751
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HF-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64904
VCAP	CCLE Cell Line Gene Expression Profiles	1.0	1.88225
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965507
PTPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22646
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25374
THNSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33211
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QK-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYO9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46695
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1466
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02887
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of b cells	GWASdb SNP-Phenotype Associations	1.0	0.368433
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836626
RPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26927
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03443
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19166
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21572
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8572
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09284
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.176084
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6115
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.070445
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64299
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05831
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97878
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17649
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GA10	CCLE Cell Line Gene Expression Profiles	1.0	1.61384
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34945
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.306
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37544
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1255
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91655
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24902
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70863
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29884
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.319
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825219
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17934
RTL8C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83512
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907457
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56168
CORL23	Achilles Cell Line Gene Essentiality Profiles	1.0	1.78449
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27972
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12313
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10673
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1_02_17	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8517-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.24056
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85832
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.541144
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49436
ACTR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74825
RAB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84957
GSE184087_0_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-11A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16424
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04734
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15423
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45006
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977975
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75782
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
hearing impairment	GWASdb SNP-Phenotype Associations	1.0	0.568635
EIF4G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02295
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14686
ZNF317	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5879
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14649
H3K9me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3545-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ZFTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7907
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65334
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS2_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04096
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21318
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77329
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68564
THOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11508
KATNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04548
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.358931
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27318
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56107
HELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53669
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874991
BRI3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63592
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1533
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40084
ACSL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56704
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.876877
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.23536
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08321
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42587
UQCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67624
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48157
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27382
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3919
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
KDM4A	ENCODE Transcription Factor Targets	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932587
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1954	Achilles Cell Line Gene Essentiality Profiles	1.0	1.30998
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13366
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65324
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68918
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2466
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27958
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89486
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.096711
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17729
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.40799
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32471
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16652
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV_48Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6471
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30059
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45583
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.227917
TRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7268
ZDHHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28174
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.227917
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76829
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29215
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954608
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.987
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84564
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43763
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25974
EZH2	ENCODE Transcription Factor Targets	1.0	null
CASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09465
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65048
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00725
PCSK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31487
Autosomal dominant auditory neuropathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.466
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78767
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TNFRSF10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98354
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29065
NO11	DepMap CRISPR Gene Dependency	1.0	2.59995
CEBPB	ENCODE Transcription Factor Targets	1.0	null
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98184
TRERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.673
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32162
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23875
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62429
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47645
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.125785
SNPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54047
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881915
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30724
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49227
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88373
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837728
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9319
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.50479
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54485
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01927
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06378
RAB11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39261
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52957
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19267
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22689
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27618
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41798
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72808
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03121
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3066
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68082
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52692
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.6147
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5653
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97515
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57919
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.67277
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66932
CDC42BPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1989
LHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50468
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16954
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65937
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89282
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11012
SLC2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47509
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834519
ZBTB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31552
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06215
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35123
KP2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.79284
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898449
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	3.40776
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04603
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61954
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35791
C7orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54262
PI4K2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7404
H3K27me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922687
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64522
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15978_KO_Tsga8_SRP254760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.83813
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32064
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.307
PGM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00267
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826281
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95767
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10596
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01724
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64582
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19199
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8515-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09523
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3463
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894933
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76573
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KALS1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05684
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40598
H3K9me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.95771
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831893
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1175
Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11674
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14949
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
PUM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74578
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02381
MIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55985
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46293
ACTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59989
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40218
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78798
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0224
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HR-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21128
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42716
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21924
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83431
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59852
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24468
IALM	CCLE Cell Line Gene CNV Profiles	1.0	1.45688
CARHSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21202
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36192
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40762
lung	HPA Tissue Gene Expression Profiles	1.0	1.19814
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65098
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50888
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929141
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98526
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193282_3_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80969
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28697
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23023
DNAJC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71075
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.089777
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23449
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02428
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4622
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58922
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4965
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30328
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.053661
Lung adenocarcinoma_LUAD_TCGA-55-6984-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
mania	GWASdb SNP-Phenotype Associations	1.0	0.478156
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69758
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926443
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4731-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.954311
TBP	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-562	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33965
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38954
TRIM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35081
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8053
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02584
SRSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1475
TF1	CCLE Cell Line Gene CNV Profiles	1.0	1.58298
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08653
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45654
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995555
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39575
FUOV1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.50876
PABIR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78785
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
CCK81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70343
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.981736
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26368
OVISE	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.4579
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47157
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39264
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5096-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11927
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31799
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30504
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08855
Autosomal recessive distal hereditary motor neuronopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
NCIH716	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10599
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS688AT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76891
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23775
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CW9019	DepMap CRISPR Gene Dependency	1.0	4.05368
ARF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72964
SF295	Achilles Cell Line Gene Essentiality Profiles	1.0	1.95084
MAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63045
SKMM2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0021
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
FBXW8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15398
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19029
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48963
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69891
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17372
MATK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77796
AP2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87177
CALCOCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39741
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69933
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28705
HS229T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51553
hearing abnormality	GWASdb SNP-Phenotype Associations	1.0	0.376013
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3048
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73911
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5976
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14907
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SARS-dORF6_48Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63706
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00091
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08799
PRRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98754
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2951
E2F4	ENCODE Transcription Factor Targets	1.0	null
MACROH2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47862
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZKSCAN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5078
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56784
NUDT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65701
JHUEM2	CCLE Cell Line Gene Expression Profiles	1.0	1.46805
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18782
RASSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75948
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37065
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61599
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5374
internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NCIH661	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82108
LEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60427
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939151
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.095437
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.993722
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15803
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867299
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7785
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94643
LRIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11967
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29408
RBBP5	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T6MN-1126-SM-4DM71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875961
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75788
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4265
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31419
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14906
JMJD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20828
SEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11401
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16335
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.53231
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36133
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	0.993678
COV434	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.62394
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965421
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52767
Juvenile spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
KRT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41478
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45389
PMC8299217-mmc4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42238
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.478156
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897538
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03885
A-Netherlands-602-2009(H1N1)_18Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.81233
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25041
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943856
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0231
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09032
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31433
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43188
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47931
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40994
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21869
MONOMAC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10393
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27618
HTK	CCLE Cell Line Gene Expression Profiles	1.0	1.44956
COLO684	DepMap CRISPR Gene Dependency	1.0	6.96045
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19185
LMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40562
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27958
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50079
C1orf198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82549
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75979
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865258
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00991
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTF2IRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22244
BL117 (ATR)	NURSA Protein Complexes	1.0	null
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.85413
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78645
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22093
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP5PO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83983
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27857
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20034
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27938
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33148
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67725
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938386
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2748
PANC1005	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4334
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21189
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30081
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923128
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27618
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25268
TPMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49711
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24723
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60049
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36457
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970368
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.160073
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.068809
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904415
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76357
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6745
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00795
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84902
NABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05339
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
CCDC85B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03968
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02817
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78344
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEMA4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22196
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35993
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNUC1	DepMap CRISPR Gene Dependency	1.0	19.323
disease	GWASdb SNP-Disease Associations	1.0	0.036294
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03429
AHCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97664
Adrenocortical carcinoma_ACC_TCGA-OR-A5K1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5561
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969687
immune system disease	GWASdb SNP-Disease Associations	1.0	0.050787
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE225647_0_v_3_srsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4428	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ABHD17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3389
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19863
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54298
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78026
FREY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22373
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21806
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36308
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899081
PMC10290283-biol-2022-0622-sm3.pdf-409-TIGD6_TIGD6	Rummagene Transcription Factor Associations 2026	1.0	null
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46363
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840451
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17453
RAF1_activemutant_219_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.88163
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
PCNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43415
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Occipital horn syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12802
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11223
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44917
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.87998
depression	GWASdb SNP-Phenotype Associations	1.0	0.357695
NELFCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97765
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47151
DGUOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57627
LN319	Achilles Cell Line Gene Essentiality Profiles	1.0	1.39187
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29831
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16463
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48284
EF-hand domain pair	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18263
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871256
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87404
Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18893
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14927
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF3B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38846
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92513
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	4.71823
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25655
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90182
CHD7	ENCODE Transcription Factor Targets	1.0	null
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02495
PROSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78656
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09971
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19325
KDM5A	ENCODE Transcription Factor Targets	1.0	null
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14858
NCIH1437	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81641
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33659
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51607
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0266
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.89401
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9535
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31933
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989471
CRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23729
COLO677	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
SSBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03744
PMC11442894-41467_2024_52678_MOESM5_ESM.xlsx-all_MSC_vs_iMPC-Unnamed_0_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19022
EGR1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24016
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15618
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.12703
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26486
NCIH226	DepMap CRISPR Gene Dependency	1.0	2.26751
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76299
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36171
Lung adenocarcinoma_LUAD_TCGA-86-8076-01A-31R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52771
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
WTX_OE_GDS4802_325_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34611
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42377
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.962884
RHOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91677
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45036
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81253
CL11	DepMap CRISPR Gene Dependency	1.0	2.51076
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59942
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01052
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33669
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858598
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SETD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75208
TIGAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94669
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11614
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71568
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.089615
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22208
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924465
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of lymphocytes	GWASdb SNP-Phenotype Associations	1.0	0.322442
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100450_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30553
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85633
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90802
CI1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76628
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.05028
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AA-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832242
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0465
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42543
NR2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52943
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6001
tauopathy	GWASdb SNP-Disease Associations	1.0	0.636511
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00768
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93422
GOS3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42229
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936938
cSARS Bat SRBD_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.49338
ACADSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11424
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17801
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14122
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15518
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.4429
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881714
CREM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07587
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.195
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	1.39773
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78761
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46996
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80292
FLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77218
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82717
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4681
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01127
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1568	DepMap CRISPR Gene Dependency	1.0	6.11094
Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48258
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05352
SOX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72425
IFFO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35728
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0239
CS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66443
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99755
HS751T	CCLE Cell Line Gene Expression Profiles	1.0	1.60822
Lung squamous cell carcinoma_LUSC_TCGA-22-4605-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32973
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35752
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56979
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47W-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C2BBE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65978
PEPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47687
SNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0911
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28045
DHRS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60279
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32675
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76524
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62987
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58902
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04306
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31178
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01053
RSRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20986
UBA52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0698
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08732
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33965
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44295
hsa-miR-4273	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
MIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4065
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02334
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871141
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
SCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53352
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86957
SW954	DepMap CRISPR Gene Dependency	1.0	2.38872
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67319
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.22263
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91003
CLCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72177
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843657
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.930871
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00593
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854209
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.48805
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915858
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55289
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03219
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70454
CASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13087
GTEX-PSDG-1026-SM-48TCV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943829
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82258
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40696
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53089
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51069
hsa-miR-1231	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X-linked distal spinal muscular atrophy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49168
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12575
HCC827	CCLE Cell Line Gene CNV Profiles	1.0	1.32829
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
TSHZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89575
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970344
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872921
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29709
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.987522
SNU840	CCLE Cell Line Gene CNV Profiles	1.0	2.35701
Pancreatitis	DisGeNET Gene-Disease Associations	1.0	null
OE33	DepMap CRISPR Gene Dependency	1.0	2.06964
cholesterol	GAD Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2029	CCLE Cell Line Gene CNV Profiles	1.0	1.92221
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937879
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17473
OPM2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.52478
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EJM	CCLE Cell Line Gene Expression Profiles	-1.0	-3.75971
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36085
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09298
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.858456
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30462
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.916623
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.35094
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57823
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62872
bed nucleus of stria terminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94106
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64175
TAF1	ENCODE Transcription Factor Targets	1.0	null
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71276
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5968
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53885
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	2.84158
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12336
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33659
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.13337
MCCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98403
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29956
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95555
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92593
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKMEL5	CCLE Cell Line Gene Expression Profiles	1.0	1.57829
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42587
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1734	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12135
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52558
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27929
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54809
WTX_OE_GDS4802_34_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MTHFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89327
DNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93324
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52684
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08415
OCUG1	DepMap CRISPR Gene Dependency	1.0	3.35557
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39384
KLHL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57104
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50076
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26054
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18634
COPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45468
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57171
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.501699
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2544
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9786
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04926
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980738
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal vocalization	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48994
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1201
UBALD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87046
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0345
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12906
TRMT61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06346
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63164
ZNF155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07716
DNLZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94159
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46321
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03497
EIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13092
16912175-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.42244
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16021
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87378
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54082
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.862662
MAP2K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18392
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	1.0	0.94337
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932587
PCDH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03135
Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883399
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969687
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91117
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59652
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10403
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09111
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32229
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59137
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15635
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985605
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89043
RBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55584
RASGRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91374
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231648_0_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BUD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07449
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.070731
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
C12orf4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54344
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89358
PARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40971
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79687
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.16785
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13328
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35596
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.090112
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97296
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCILY19	CCLE Cell Line Gene Expression Profiles	1.0	1.40492
Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33787
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74277
GTPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6142
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98139
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.998358
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.175934
bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66006
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.993722
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7204
PAGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95734
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90508
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45532
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843077
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4263	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CALM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98828
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19816
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36282
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60994
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45078
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862955
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53959
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00578
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00567
NAMALWA	CCLE Cell Line Gene Expression Profiles	1.0	1.62049
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08469
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15935
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.060197
COV504	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59542
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94744
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_24_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MRPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43855
PMC7899452-media-5.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
HEXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3704
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34076
ARMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18237
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833063
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77389
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
b cell deficiency	GWASdb SNP-Disease Associations	1.0	0.265055
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48373
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30413
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57484
hsa-miR-3064-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19499
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09023
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10967
ADCY9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51073
KMS11	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.64292
JMJD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47791
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26327
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929141
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90515
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
ZNRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50761
FMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2158
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10388
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JKAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35113
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95364
LN235	Achilles Cell Line Gene Essentiality Profiles	1.0	1.75324
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32914
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02768
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04236
HS611T	CCLE Cell Line Gene Expression Profiles	1.0	1.90174
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38635
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.37347
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19081
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57801
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82772
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45109
NKX1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32713
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96705
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.162
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04834
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99307
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77545
JHESOAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5205
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
ZNF600	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50583
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44303
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862423
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970344
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42539
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07111
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_0_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.33762
APP	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.82438
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CROCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85634
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05565
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874054
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.43069
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMM10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03412
DDX53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27041
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10886
primary immunodeficiency disease	GWASdb SNP-Disease Associations	1.0	0.231646
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36476
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50904
IPC298	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73323
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68769
HUG1N	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.36676
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45391
P2RX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66571
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.454
DPAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16035
HCC1954	DepMap CRISPR Gene Dependency	1.0	3.95754
PMC11903305-41586_2024_8507_MOESM3_ESM.xlsx-Table_S1_MAF-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16052
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4505	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19694
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.69
TOLEDO	CCLE Cell Line Gene Expression Profiles	1.0	1.90968
JHU011	DepMap CRISPR Gene Dependency	1.0	2.60698
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
TES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04414
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39603
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55719
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01198
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861029
dysgammaglobulinemia	GWASdb SNP-Disease Associations	1.0	0.35858
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48206
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.85145
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887681
SOX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49156
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28364
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06644
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3047
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12296
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.483421
COX8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32703
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12926
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909005
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
LYRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48078
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21929
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3671
RFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92001
NINJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04078
CD83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81274
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26218
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.636511
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36116
c-reactive protein	GAD Gene-Disease Associations	1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.5815
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.969009
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
PMC11214527-mmc5.xlsx-ADNP-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75788
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98443
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82564
CNOT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.585
KMRC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65824
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82564
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929059
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84483
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51827
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16337
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.561109
AP3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65996
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.57896
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75145
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45945
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31076
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34218
OCILY3	CCLE Cell Line Gene Expression Profiles	1.0	2.09759
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67097
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4362
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63213
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56923
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852503
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44114
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81553
FLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42195
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03256
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MF-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18819
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.55081
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0393
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90418
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01271
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00117
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	2.09602
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05743
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	1.90068
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.050636
ADGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49125
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78622
abnormal vocalization	IMPC Knockout Mouse Phenotypes	1.0	null
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866552
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32381
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40487
all	GWASdb SNP-Phenotype Associations	1.0	0.037672
Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52901
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
GI1	CCLE Cell Line Gene CNV Profiles	1.0	2.60358
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV3-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMK1	DepMap CRISPR Gene Dependency	1.0	3.05951
GSE156667_0_v_1_lrrc8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02632
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42587
MFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72398
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
LRRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47499
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20958
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891044
dementia	GWASdb SNP-Disease Associations	1.0	0.363486
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69114
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27084
H3K27me3_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	1.43851
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.94052
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48715
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.022417
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13832
NMRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09183
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2108
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46184
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.12694
NCIH1373	DepMap CRISPR Gene Dependency	1.0	2.37589
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28878
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831978
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAPGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68867
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37423
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13986
FAAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4165
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923128
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10676
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74565
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32352
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73105
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79704
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03077
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09658
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26238
abnormality of b cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.368433
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58393
GSE142684_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37451
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RPS6KA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41856
DESI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95306
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	2.21392
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07111
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969398
hsa-miR-3175	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75735
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16711
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67029
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9015
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21923
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	3.83357
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08079
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12272
CUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50503
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51745
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.866637
TRUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89187
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04696
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906238
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77081
HEY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26964
MRPL50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5621
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34771
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02423
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2587
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIPRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78437
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79535
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88249
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERFLCKJ	CCLE Cell Line Gene CNV Profiles	1.0	1.72859
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ST3GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72185
GCT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78596
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	3.18675
SW1990	DepMap CRISPR Gene Dependency	1.0	2.74199
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929999
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54407
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75204
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LIPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08721
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00969
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80409
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42587
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93482
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32092
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8158
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1147
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04659
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91722
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24151
HCC44	Achilles Cell Line Gene Essentiality Profiles	1.0	1.26471
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11531
Autosomal recessive distal hereditary motor neuronopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68098
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51593
SUDHL5	DepMap CRISPR Gene Dependency	1.0	5.87166
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.268629
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.965301
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
RUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61041
selective immunoglobulin deficiency disease	GWASdb SNP-Disease Associations	1.0	0.35858
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54846
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0726
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3081
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1255
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16782
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992587
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50424
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30078
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965509
RCOR1	ENCODE Transcription Factor Targets	1.0	null
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880231
OSC19	DepMap CRISPR Gene Dependency	1.0	3.40466
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21949
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.079189
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.62092
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896016
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984209
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.92495
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22587
MONOMAC6	Achilles Cell Line Gene Essentiality Profiles	1.0	1.13054
lung	GTEx Tissue Gene Expression Profiles	1.0	1.03926
PER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52683
NCIH2228	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0552
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13383
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.01864
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29401
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1048
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58698
HTR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22645
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878088
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970061
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_maintained-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93607
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33659
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77487
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.85811
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32352
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39605
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
GSE173873_8_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	1.0	1.74417
CDKN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18954
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30217
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871029
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898263
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19323
GAS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99003
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830112
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.35879
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.267
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.93456
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44791
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GADD45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43028
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39123
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88505
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00177
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72124
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.48805
LI7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47429
ATP6AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9563
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52083
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860103
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64418
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-5155-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981772
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT474	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.35059
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54599
RERF-LC-MS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07729
EGR1	ENCODE Transcription Factor Targets	1.0	null
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E6-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.075129
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861861
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31166
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0093
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880232
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05743
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37823
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78012
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64979
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2749
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997957
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82564
SMAD4	ChEA Transcription Factor Targets	1.0	null
PODXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94225
Rectum adenocarcinoma_READ_TCGA-AF-6136-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34896
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.40628
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95392
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13292
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93199
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902682
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.249263
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.920785
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C-Reactive Protein	dbGAP Gene-Trait Associations	1.0	0.064987
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847145
CEP164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93729
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30249
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980303
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02368
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31241
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54367
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831726
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07325
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968861
DND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41428
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09527
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914142
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
GI-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.12703
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826281
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00569
RSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96348
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91513
MAX	ENCODE Transcription Factor Targets	1.0	null
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71955
DMS273	CCLE Cell Line Gene Expression Profiles	1.0	1.45242
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97977
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60307
H2BC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10194
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5056
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18948
CHCHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20336
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42097
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26963
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COV362	CCLE Cell Line Gene Expression Profiles	1.0	1.52953
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5828
IM95	DepMap CRISPR Gene Dependency	1.0	5.32518
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969208
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10895
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03693
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849864
Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.76609
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41677
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48908
SLC19A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08714
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67219
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0296
RCM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97751
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51586
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891572
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894664
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-2.31155
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31838
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951719
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29368
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13975
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4148
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997515
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HQ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08121
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30946
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64395
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13636
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
NMB	DepMap CRISPR Gene Dependency	1.0	7.3085
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.038366
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939273
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97516
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9879
CTCF	ENCODE Transcription Factor Targets	1.0	null
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53069
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E2-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35807
COV644	CCLE Cell Line Gene Expression Profiles	1.0	1.62706
Adrenocortical carcinoma_ACC_TCGA-OR-A5LR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18362
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45397
DOV13	CCLE Cell Line Gene CNV Profiles	1.0	1.60266
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54952
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03083
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
SIN3B	ChEA Transcription Factor Targets	1.0	null
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.09115
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
RAB39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91678
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2841
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40885
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49492
NCIH647	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58626
selective ige deficiency disease	GWASdb SNP-Disease Associations	1.0	0.619466
KAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17082
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
HENMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39744
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91092
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55415
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93448
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.9881
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44182
HCT116	DepMap CRISPR Gene Dependency	1.0	2.68532
HMGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05843
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0398
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42167
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858462
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF648	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90654
CL14	CCLE Cell Line Gene Expression Profiles	1.0	1.57492
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24605
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35848
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00685
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.270563
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95311
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11674
KASUMI1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.49373
GPAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44682
NCIH2171	CCLE Cell Line Gene Expression Profiles	1.0	2.23339
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_maintained-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NR2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88045
abnormality of cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.280731
LOVO	CCLE Cell Line Gene Expression Profiles	1.0	1.4264
mood disorder	GWASdb SNP-Disease Associations	1.0	0.289097
SPAG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16392
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.12703
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82564
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35929
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54298
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.40735
AR	ChEA Transcription Factor Targets	1.0	null
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35493
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.093544
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYO1	DepMap CRISPR Gene Dependency	1.0	2.45648
Prostate adenocarcinoma_PRAD_TCGA-HC-A76X-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08021
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2749
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04579
GTEX-P4QS-0426-SM-3NMCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868972
EIF5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90811
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05227
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.41507
EMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22185
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01158
TR146	DepMap CRISPR Gene Dependency	1.0	2.16612
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929085
ABC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92711
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43358
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61087
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95239
HUPT4	DepMap CRISPR Gene Dependency	1.0	4.29975
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8585
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.10123
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of humoral immunity	GWASdb SNP-Phenotype Associations	1.0	0.280731
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-103b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08338
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95233
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54174
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829707
MTA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74103
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942345
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94237
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07623
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.50568
abnormality of the ear	GWASdb SNP-Phenotype Associations	1.0	0.291178
C2orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11998
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970916
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66717
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.77866
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.49373
TSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8845
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1397
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HG-A2PA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909807
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
CLNS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08206
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02338
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18144
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46312
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22587
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80519
chr1_59995061_C_A_b38	GTEx eQTL 2025	1.0	1.5417
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91327
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918867
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69447