association	dataset	threshold value	standardized value
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03984
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.70701
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0026
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3121-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC7927379-12864_2021_7476_MOESM1_ESM.txt--MI_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37659
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00634
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.873
C4orf46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47123
TEAD4	ENCODE Transcription Factor Targets	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5325
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.033761
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.20593
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76684
CEND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18194
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27306
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07136
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DENR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43861
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2028
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367239
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91897
GTEX-WL46-0426-SM-3TW8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48798
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75942
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00427
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.15513
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00791
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835181
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6258
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41325
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54725
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841059
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941304
hsa-miR-4464	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RC-52-AC88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310066
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38144
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
C-28/I2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.464
RCOR1	ChEA Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4474-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Perturb_6447_OE|KD_EGFR|TRIM24_SRP100743	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29975
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-81-VY50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.596924
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.856824
GSE118490_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.5473
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34423
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CD-97-ZV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201508
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
hsa-miR-4748	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998212
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-30-CR11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418203
GTEX-S3XE-0326-SM-4AD6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994778
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A9-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
AA-62-JP26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31353
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050266
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	1.77847
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62702
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.38842
regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28239
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SYT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8566
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein heterotrimerization	GO Biological Process Annotations 2015	1.0	null
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.01105
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SISO	DepMap CRISPR Gene Dependency	1.0	2.82041
PB-09-OE00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301516
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.911774
BFTC909	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72382
STAT1_KD_GDS4754_159_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4484
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58748
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.438
EGR1	ENCODE Transcription Factor Targets	1.0	null
BACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53816
USO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08927
blood vessel	GTEx Tissue Gene Expression Profiles	1.0	1.69116
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.944524
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.545712
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08871
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0298
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05625
BD-81-LB65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.556577
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45523
Gastrointestinal stromal tumor_Gastric Tissue_GSE15966	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.62332
GTEX-S4Z8-0926-SM-4AD6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861524
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829848
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96421
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLTC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10132
SYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16502
FBXO28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2558
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased circulating VLDL cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28204
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of lipid metabolic process	GO Biological Process Annotations 2023	1.0	null
AC-28-RT00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.505275
NB-80-IM48_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201545
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328112
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.92136
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-0926-SM-4LMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978356
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49639
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-R55E-0326-SM-48FD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58773
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IC-76-JU42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287002
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18012
SAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99589
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.39492
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932089
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937439
MTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5489
PD-60-FM93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228587
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.02938
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38248
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32851
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23667
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MA-43-MR37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371801
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15045
bladder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.958966
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03754
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SD-82-GT69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.757411
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.18039
Mlxip	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44323
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35572
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77J-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65977
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78645
Necrosis	CTD Gene-Disease Associations	1.0	1.17629
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208373
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OC-40-XI13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296679
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.3637
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69699
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08574
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC70	CCLE Cell Line Gene Expression Profiles	1.0	1.38729
TF-29-QU48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.85986
increased circulating glycerol level	MGI Mouse Phenotype Associations 2023	1.0	null
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94808
DDX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23791
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06461
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.94896
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03032
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r1 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04222
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56724
DRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67438
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864409
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9963
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410492
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901962
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-5_Comparisons-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
increased circulating triglyceride level	MGI Mouse Phenotype Associations 2023	1.0	null
MMAC	DepMap CRISPR Gene Dependency	1.0	2.55654
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
FC-35-BX82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.39304
decreased lean body mass	MGI Mouse Phenotype Associations 2023	1.0	null
AD-52-UZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200091
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00326
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02792
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
DYRK1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48869
enhanced lipolysis	MGI Mouse Phenotype Associations 2023	1.0	null
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81596
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148494,GSE182513_1_v_0_hoxd13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.635523
Cmah_KO_GDS4770_421_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XV7Q-1226-SM-4BRVT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938755
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
CTAGE15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43132
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64287
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881713
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09983
NB-12-ZK38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.597026
CE-15-YU05_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231247
NFIC	ENCODE Transcription Factor Targets	1.0	null
GSE199078_1_v_0_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34169
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
positive regulation of lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.34338
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93851
hsa-miR-876-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICC9	DepMap CRISPR Gene Dependency	1.0	2.80093
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.499298
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944897
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.742
SW1573	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63836
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2231
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63766
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0555
r5 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19363
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850843
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866986
SHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38542
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02369
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YE-80-LN04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742621
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.518092
OE-84-HO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247701
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0667
SPIB	JASPAR Predicted Transcription Factor Targets	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.98014
Perturb_10638_Mut_Cryaa_SRP104440	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.36351
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56121
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-427-PRRX1_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.02041
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49237
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.55999
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32226
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.40366
REXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01927
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.831256
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23273
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17116
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897868
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.702813
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.933359
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased liver cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
lateral part of preisthmic periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60348
NIPAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90703
positive regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
liminal part of r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70212
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58145
regulation of generation of precursor metabolites and energy	GO Biological Process Annotations 2015	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03022
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
MXI1	ENCODE Transcription Factor Targets	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4424
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.92538
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349502
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14328
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22406
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SFRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56492
H3K27me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
DA-27-BW40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287673
AP-1 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02984
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09338
JE-22-JR20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204821
Deuterosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-R53T-0826-SM-48FCP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06737
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490217
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438333
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00978
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51415
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	1.66305
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.69352
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0026
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	5.82848
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
SJRH30	CCLE Cell Line Gene Expression Profiles	1.0	2.29058
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964137
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23301
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4783
H3K27me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466539
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-Unnamed_35_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66228
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05162
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01746
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.561298
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.808249
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52301
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46675
BF-26-MB27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316111
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of mapk cascade	GO Biological Process Annotations 2015	1.0	null
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09749
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.232
JUN	ENCODE Transcription Factor Targets	1.0	null
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.972502
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27337
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304816
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.953162
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19823
regulation of transferase activity	GO Biological Process Annotations 2015	1.0	null
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-30-BE85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440199
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6215
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Y79	DepMap CRISPR Gene Dependency	1.0	2.51439
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BB-86-BE39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.755371
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RH-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23391
AM38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75451
BA-59-EN38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358861
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60688
GTEX-R53T-0726-SM-48FCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77807
mantle zone of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76894
CLDN18_KO_GSE48443_44_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22406
HSFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5849
protein homooligomerization	GO Biological Process Annotations 2015	1.0	null
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478128
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3504
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2323
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471082
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988038
FE-82-WB22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.541744
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TB-06-VB30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.931881
DB-07-WB29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32958
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39438
GTEX-POMQ-1226-SM-3P61F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39656
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.071362
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18473
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833917
RH30	CCLE Cell Line Gene Expression Profiles	1.0	2.6277
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20701
GSE134375_6_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased epididymal fat pad weight	MGI Mouse Phenotype Associations 2023	1.0	null
DC-22-OP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424539
AE-17-IZ62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415596
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316413
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.866581
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	150.294
PMC8102188-41375_2021_1231_MOESM4_ESM.xlsx-t_som_AA_healthy-Unnamed_7_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83576
regulation of fatty acid oxidation	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39971
hsa-miR-3116	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PC-62-AQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361502
GTEX-QDT8-1326-SM-48TYY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823937
LARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30735
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.812247
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I1-06A-12R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.51449
PMC10082046-41467_2023_37049_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_Genes_upregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWOO-0426-SM-48TZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903588
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24783
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91336
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.26906
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46748
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.835178
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66146
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.54708
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24403
MRPL55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61702
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59121
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86802
NIPBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70421
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.454274
Systemic scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01165
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44163
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37649
EZH2	ENCODE Transcription Factor Targets	1.0	null
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828674
hsa-miR-4725-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73834
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00253
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3158
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H5-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842616
SNU5	CCLE Cell Line Gene CNV Profiles	1.0	1.62645
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.49403
U-87-MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.632
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06125
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FF-34-KW62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.886255
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0566
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH18	CCLE Cell Line Gene Expression Profiles	1.0	1.53232
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65478
GTEX-RWS6-0526-SM-4GIAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27983
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313632
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23011
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08013
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.980154
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842465
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17959
GTEX-S33H-0626-SM-2XCBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873154
colonrectum_b	HPA Tissue Sample Gene Expression Profiles	1.0	0.826942
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04171
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39266
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4216
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
collagen trimer	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Clathrin coat of trans-Golgi network vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gout	GWASdb SNP-Disease Associations	1.0	1.04898
PMC8047323-Table_2.xlsx-LPS_PMMA_T24-GeneSymbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936336
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.518209
MAX	ENCODE Transcription Factor Targets	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76894
regulation of fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Arntl	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2239
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42045
GTEX-S95S-0226-SM-4B656	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57613
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73373
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CK-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BA-95-YU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.872805
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03216
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51198
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35047
NF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53599
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46384
adrenal gland	HPA Tissue Protein Expression Profiles	-1.0	-0.944524
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884228
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.944524
WC-09-GD62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.672825
H2BK15ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.97792
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31815
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955492
RUNX1_KO_GDS1511_250_mouse_Embryos at E8.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978947
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.37226
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2658
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00451
regulation of carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02214
LE-60-VC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315552
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BA-84-TD72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.456232
TGBC11TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48624
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19363
Scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.472642
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-5_Comparisons-E2F2_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54798
Lung adenocarcinoma_LUAD_TCGA-78-8648-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3829
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100591_TCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05821
Pontine reticular nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22406
r4 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33113
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.90077
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001517
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78492
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.829238
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08069
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02575
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336985
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.2122
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
USF1	ENCODE Transcription Factor Targets	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68849
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42474
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424682
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
PTGIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25252
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	1.0	null
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05162
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49222
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CF-42-OS28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.66401
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952611
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10526
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.747372
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57801
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06702
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4627-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17938
NKX1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09525
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09078
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87049
PBX1	ChEA Transcription Factor Targets	1.0	null
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07564
HF-79-EC41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339834
hsa-miR-4735-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.584128
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10715
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40876
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	1.0	null
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393793
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240021
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11549
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69685
late-onset retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.005
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49365
protein complex subunit organization	GO Biological Process Annotations 2015	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.917955
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838381
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61639
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
macromolecular complex assembly	GO Biological Process Annotations 2015	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4264
positive regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35804
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CNTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42833
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.84422
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852634
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4721
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.525946
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41423
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.808
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42903
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.04479
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5655
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847698
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9419
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74739
SLC7A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29639
BB-11-JI42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267874
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.212
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24041
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888775
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	5.02613
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.67626
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35503
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	4.95206
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304422
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K23ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892924
BF-22-EP86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.628918
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.957123
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34019
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TTC38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46131
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49017
CPEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78045
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9616
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7045
LS-513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73406
DB-56-XL71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.512683
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16879
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55342
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.030747
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964379
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56365
COPG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69106
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0799
UC-00-QA88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219405
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00602
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864852
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828961
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63299
DD-43-WW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203716
ULK1_knockout_197_GSE60778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.99438
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57488
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09612
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325392
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OV56	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67744
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977266
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
dorsolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09277
BD-61-OO16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.674103
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13189
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.549543
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829848
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303411
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893538
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.38637
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888137
FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.934492
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495494
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66098
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17959
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14741
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829848
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
decreased circulating LDL cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.19812
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small liver	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89071
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24558
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00369
H2BK120ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00821
PMC5986551__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31111
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27732
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2528
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
hsa-miR-936	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
HCA1	DepMap CRISPR Gene Dependency	1.0	9.0545
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90725
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21882
protein binding	GO Molecular Function Annotations 2015	1.0	null
BT16	DepMap CRISPR Gene Dependency	1.0	3.93688
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64658
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53457
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4167-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912106
primary motor cortex (area M1, area 4)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.948443
19139136-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OHPK-0426-SM-3MJH3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13545
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.803185
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62199
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.882409
p3x63ag8.653	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94369
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16652
increased circulating VLDL triglyceride level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.961949
BC-61-ZY95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.780827
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.975753
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MERO83	DepMap CRISPR Gene Dependency	1.0	8.71362
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34834
OB-17-DQ74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.426571
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-16-IU17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.666231
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06163
GSDMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17401
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.824558
GTEX-UPK5-1526-SM-4JBJA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01297
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838885
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38071
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65385
Tumour necrosis factor-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-1976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001526
MF-41-QM60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215683
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50666
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06119
DA-35-DU85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316453
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52034
2313287	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95948
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.866257
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09659
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54374
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964834
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35455
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50951
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879448
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
cellular_component	GO Cellular Component Annotations 2015	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00785
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.954305
Complement C1q protein	InterPro Predicted Protein Domain Annotations	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20188
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49923
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949263
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-759	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
496100386_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27697
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98837
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94919
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32598
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.944524
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.382
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84792
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35089
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15284
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1088
U178	CCLE Cell Line Gene Expression Profiles	1.0	2.35967
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.52321
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23024
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GE-40-GQ38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247947
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.71773
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.821093
AD-86-OB87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213367
ESYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
EC-82-LV30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292349
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oculomotor nucleus, Edinger-Westphal subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12854
MA-43-MR37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33254
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.52117
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828961
HKA1	DepMap CRISPR Gene Dependency	1.0	2.11822
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357698
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9415
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15389
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31728
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85046
GSE121319_1_v_2_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31541
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF619	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47488
intermediate stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02214
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LA-44-KW22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401506
PMC2694838-1471-2164-10-241-S3.xls-Sheet1-Commonly_altered_genes_by_ZNF191_overexpression_and_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
JC-63-DO70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243345
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68835
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90753
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423453
Cardiomyoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984134
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer III of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844544
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03272
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-509-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52516
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.391571
GTEX-PLZ5-0426-SM-3P612	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0715
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.6664
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
BB-87-SF89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276181
mantle zone of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70212
BF-49-KQ10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256187
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46867
PROSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76202
Aortic arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EC-98-KI28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.474619
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COV504	CCLE Cell Line Gene Expression Profiles	1.0	1.42503
EA-81-CR68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376594
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5365
Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.545769
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21757
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2078
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6466
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330025
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.04684
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29237
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389907
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239917
regulation of carbohydrate biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3296
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982068
LPS6	DepMap CRISPR Gene Dependency	1.0	2.29761
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03264
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842319
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946745
DA-66-OE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.660411
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3173
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12658
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884489
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86311
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
E2F6	ENCODE Transcription Factor Targets	1.0	null
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.882814
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9196
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20353
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49937
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01443
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47839
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26451
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8777
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11184
AD-51-LE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266665
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1404
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-1326-SM-4AD74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978069
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBX2	ENCODE Transcription Factor Targets	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.73328
H2BK12ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATF3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76894
RHOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91677
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.67549
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.944524
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18016
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41177
RB-34-TO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06653
Lung squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64942
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.840051
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276599
HMGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70559
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-OXRL-0426-SM-3NM97	GTEx Tissue Sample Gene Expression Profiles	1.0	1.019
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0965
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-643	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.930075
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.790701
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal liver physiology	MGI Mouse Phenotype Associations 2023	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65374
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1088	CCLE Cell Line Gene Expression Profiles	1.0	1.38698
Acute Myeloid Leukemia_LAML_TCGA-AB-2881-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856964
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871447
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13038
decreased circulating cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998406
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.956672
KMS34	DepMap CRISPR Gene Dependency	1.0	3.58625
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
extracellular matrix part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70993
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945369
TD-48-XJ84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.446705
GTEX-U4B1-0226-SM-4DXU8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18228
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69238
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67512
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09327
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32581
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00022
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
CORL279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32217
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73594
hsa-miR-4722-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
LUC7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39472
NF-21-HQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.774378
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242005
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32267
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.52064
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
heart_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03162
FB-33-LI31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256453
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04647
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1881
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67529
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94216
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.956
HG3	DepMap CRISPR Gene Dependency	1.0	6.30724
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BF-27-HP68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288688
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.920769
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914469
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32027
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.93486
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07091
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.480118
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48615
S0-EE-Y6WJ_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.527793
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43279
GTEX-X88G-0426-SM-47JZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0871
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.764234
NCIH1373	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56966
Eye-corneal keratocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.285186
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.47456
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.70079
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BQ-01C-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.4474
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0126-SM-3GADM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76296
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59302
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272345
GTEX-X4EP-0826-SM-3P5YK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15864
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08579
Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02976
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07812
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24383
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	DepMap CRISPR Gene Dependency	1.0	3.94615
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38051
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TIRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6991
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.938032
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4031
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2099
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.05335
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33049
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266081
C-33A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HD-51-KD29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233493
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65788
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73217
AC-50-FR41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.942006
mRNA_NR0B1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829848
positive regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25421
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6322
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-0.944524
positive regulation of map kinase activity	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5010-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
regulation of primary metabolic process	GO Biological Process Annotations 2023	1.0	null
BA-29-OX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286257
GTEX-U3ZH-0426-SM-4DXSE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12743
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95527
positive regulation of glucose import	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4799-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60348
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23766
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00242
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19366
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91828
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4595
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4103
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02655
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98074
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TP63_01_199	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.84358
BCL9L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13527
ERRFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33874
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.61492
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287701
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26372
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T8EM-0426-SM-4DM7E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43032
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00531
AF-30-GH67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244196
QD-32-CW16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458833
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48591
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22776
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89486
PITPNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71305
u251mg	HPA Cell Line Gene Expression Profiles	1.0	0.894595
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885676
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.920151
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27565
PDIA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2039
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5345
PPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25457
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7949
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
VRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68677
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06205
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980933
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.956672
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68388
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41256
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53665
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61674
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59059
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09986
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01851
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-289-E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43506
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22014
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919947
GA-59-RW04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.972213
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
DE-97-IV02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04931
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03361
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08211
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530029
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937439
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05452
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of polysaccharide biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02544
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.163
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03309
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34757
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832286
extracellular space	GO Cellular Component Annotations 2015	1.0	null
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	2.1776
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02641
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27287
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830858
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288114
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83317
HICS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834012
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63032
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413595
BE-47-IP08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209688
CB-82-PL01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281627
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5203
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295297
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.853145
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856035
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COMMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30149
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93921
GSE220520_5_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Feather vane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.164
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.856729
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KG1C	CCLE Cell Line Gene CNV Profiles	1.0	1.42669
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17959
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10686
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.880498
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
QA-34-PH05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.899268
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40505
SHOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15622
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r4 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35276
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN382	CCLE Cell Line Gene Expression Profiles	1.0	1.58239
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41639
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18211
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12647
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875858
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9675
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00594
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-11A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FD-25-KX07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.701839
regulation of localization	GO Biological Process Annotations 2015	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-LI-A67I-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_31_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.21367
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09797
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FE-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4643
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12437
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RABGGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65945
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP6R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28427
ELF1	ChEA Transcription Factor Targets	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-5_Comparisons-E2F8_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
AC-97-KP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234613
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0626-SM-3NMAN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930704
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
F5	DepMap CRISPR Gene Dependency	1.0	3.86055
Sarcoma_SARC_TCGA-DX-A23Z-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898602
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NS-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00717
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50075
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63393
MBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96336
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.376
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42031
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.953601
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08635
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4697
regulation of polysaccharide metabolic process	GO Biological Process Annotations 2015	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.674806
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89614
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838885
DDX50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31903
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
AA-48-XT80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280715
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLSTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15211
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27437
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GD-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-84-PK04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212213
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21672
Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4468	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
496100666_HIP_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24522
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23592
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30666
EF-92-OO68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.467054
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DD-38-BM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51661
ZNF43_01_125	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63134
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95595
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.81822
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60348
Perturb_3761_KD_VPS28_SRP325061	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.48028
Collagen triple helix repeat	InterPro Predicted Protein Domain Annotations	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02668
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04171
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38119
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28298
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
S0-EE-YNU4_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301294
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8242
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13788
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A7DR-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
smoothmuscle_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.09644
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67279
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02729
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.919534
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33434
496100329_FWM_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3698
AE-04-SN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.582859
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18746
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950876
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-25-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.557876
LSM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12476
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.31981
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.61
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MKN7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439061
BB-11-JI42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.586685
MYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94576
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44253
TRMT61A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62954
AC-50-FR41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51956
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553568
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-88-PW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248705
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28769
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824222
Perturb_16432_OE_E2f4_SRP327850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.3558
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938556
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854027
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14232
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25554
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74232
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL30	DepMap CRISPR Gene Dependency	1.0	2.415
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4889-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311646
FOS	ENCODE Transcription Factor Targets	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.718373
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972279
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54914
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471766
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JAG1_OE_GDS3571_40_human_endometrial stromal cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941253
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27685
Acute Myeloid Leukemia_LAML_TCGA-AB-2805-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.75544
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.19515
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58121
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64595
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236579
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6028
ZNF793	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27345
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-2.47975
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-CoV_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.30314
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19323
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.926419
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74169
KYSE-150 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
Poisoning	CTD Gene-Disease Associations	1.0	1.08126
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64718
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14467
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891637
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.583872
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3083
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25558
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
regulation of glucose metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04954
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40114
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55E-1126-SM-48FDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08203
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.04337
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04697
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3809
LN215	CCLE Cell Line Gene Expression Profiles	1.0	1.77074
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.686749
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63208
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36547
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1661
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.902384
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29813
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.872233
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.904015
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.527734
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26588
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A4S6-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64736
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871508
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22365
U2OS	CCLE Cell Line Gene Expression Profiles	1.0	1.55928
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08211
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-50-FR41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392326
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
decreased circulating HDL cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.66894
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08211
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45362
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17291_OE_lncRNA5251_SRP239064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.11747
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20953
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18119
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.19113
GTEX-S4P3-0326-SM-4AD6P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92212
CD-20-GE75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.572985
liminal part of r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40114
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43907
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arthritis	GWASdb SNP-Disease Associations	1.0	0.330847
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0785
ITPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22684
r2 part of the ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08265
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07136
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21001
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2557
Prostate adenocarcinoma_PRAD_TCGA-G9-6378-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4021255__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-PLZ6-0326-SM-3P61J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965398
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359416
ARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73508
BB-23-PM31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.549713
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00565
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-00-YH62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248047
Perturb_6495_KD_PIEZO1_SRP392492	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A1KZ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28454
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48073
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3WB-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DD-26-VR55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264364
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1801
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCC10RGB	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08637
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90527
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20701
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48858
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980555
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EC-41-PH99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.595715
RAB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31781
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09511
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
hsa-miR-3664-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911059
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6493
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49463
FJX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16062
GTEX-T2IS-0926-SM-4DM5B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888483
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.84337
hsa-miR-509-3-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20701
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33113
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05248
AB-80-CK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.885487
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.90905
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61599
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.978029
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330868
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8778
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240049
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76406
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2657
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.71567
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BE-90-YK54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215147
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37998
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
protein complex assembly	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4159-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.877375
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29278
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.590843
FC-22-VC55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213558
CEBPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1352
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.892702
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941087
EC-82-LV30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463389
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Primary enamel knot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.598
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20915
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82286
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55993
FNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.40688
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20835
positive regulation of protein serine/threonine kinase activity	GO Biological Process Annotations 2015	1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39361
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32337
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971733
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836984
GTEX-S3XE-0226-SM-4AD6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869622
GTEX-XQ3S-1026-SM-4BOPJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18341
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625396
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-0626-SM-4LMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960376
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5138
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885752
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09672
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240164
GTEX-PSDG-1026-SM-48TCV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997233
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47838
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27689
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GA-81-DL34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.528108
GTEX-WCDI-0426-SM-4GIAL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870295
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28511
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45511
hsa-miR-1290	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03538
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364417
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.840589
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-42-FF52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381139
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965094
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934645
KA-51-CQ55_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217052
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3578
DDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34357
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970603
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08211
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16963_OE_RAB44_SRP305964	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.09761
HS618T	CCLE Cell Line Gene Expression Profiles	1.0	1.65836
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86776
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1184	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14328
PC-18-VX23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.435128
decreased body fat mass	MGI Mouse Phenotype Associations 2023	1.0	null
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469599
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0332
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5401
Benign paroxysmal positional vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90571
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
15902281-TableS1e	GeneSigDB Published Gene Signatures	1.0	null
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920089
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.01929
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980873
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59775
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.861128
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37573
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67655
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80491
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	2.332
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.881061
positive regulation of fatty acid oxidation	GO Biological Process Annotations 2015	1.0	null
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.24136
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.755793
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04463
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16174
Myopathy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.96343
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826595
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93095
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944633
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12687
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.048711
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.535104
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06923
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-550a	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.813502
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.473414
PTEN_KD_GDS2958_101_human_SKBR-3 MAMMARY ADENOCARCINOMA cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DB-73-BC12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223412
PRR15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24883
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955614
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.19224
QB-88-PG52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299855
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.704
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88839
EF-85-DA07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289349
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46199
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.543903
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.62403
GD-46-BU97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.517356
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FGFR3_druginhibition_36_GDS5023	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.67942
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19772
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.3517
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36938
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39282
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990016
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24855
hsa-miR-3943	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
TM2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60294
TE14	CCLE Cell Line Gene CNV Profiles	1.0	3.27092
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.77652
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.297542
19168792-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13409
hsa-miR-4802-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YC-45-JD42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.501258
JF-62-LU77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.52819
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73355
hsa-miR-4672	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989971
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61672
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Multimerin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.255
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81972
raphe nuclei of medulla	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932715
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.614467
r1 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02214
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
CD-05-PU90_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469107
NE-00-JZ19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.632432
BE-73-KD75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309479
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.8923
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41594
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988565
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-11A-12R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF708_01_130	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60218
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02307
GSE207433_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858493
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19535
AD-54-FG24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388419
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401561
SA-03-IQ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406575
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.735311
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.1759
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8139
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03216
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481586
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.31267
Lung adenocarcinoma_LUAD_TCGA-50-5932-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52967
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2326
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08211
GTEX-REY6-1126-SM-48FDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874669
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54102
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400916
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GLDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55469
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31079
receptor binding	GO Molecular Function Annotations 2015	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43037
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5392
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80351
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43543
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1159
TBL1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56455
bj	HPA Cell Line Gene Expression Profiles	1.0	0.841481
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96377
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873969
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10904
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1566
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85975
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.832499
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925791
ACCMESO1	CCLE Cell Line Gene CNV Profiles	1.0	1.51556
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32814
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-518b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272004
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91843
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.67252
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857183
GTEX-S341-1126-SM-4AD6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06746
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-04-SN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32431
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RO-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.93443
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37062
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12567
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26372
Lung squamous cell carcinoma_LUSC_TCGA-39-5019-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21859
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7992
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37638
UBTF	ENCODE Transcription Factor Targets	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26093
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26525
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02742
DC-23-UM36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455092
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PF-59-CY33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29656
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	2.85231
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73869
SKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32396
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14499
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.84636
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.77885
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905478
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.960565
Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE67266_5_v_1_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35276
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.997979
decreased inguinal fat pad weight	MGI Mouse Phenotype Associations 2023	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46502
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.740173
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956685
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18218
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
positive regulation of signaling	GO Biological Process Annotations 2015	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
vascular disease	GWASdb SNP-Disease Associations	1.0	0.065504
BC-13-OQ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.608716
MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840285
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58328
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
HA-22-CY42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223109
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42442
ANKRD49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84696
GTEX-RN64-0726-SM-48FCV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57068
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857879
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332494
positive regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.95902
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.4063
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16598
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
isthmic liminal reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09338
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949358
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
decreased liver triglyceride level	MGI Mouse Phenotype Associations 2023	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828961
BB-84-DG64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229363
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13077
EE-02-BO83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204681
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.842119
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21281
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
collagen trimer	GO Cellular Component Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04236
SJSA1	CCLE Cell Line Gene Expression Profiles	1.0	1.37073
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UFSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6208
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74888
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82563
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53947
positive regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16673
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.940333
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LF-94-HB11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223156
XD-08-ZW85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.687085
ventrolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0657
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34734
GTEX-WFON-0526-SM-4LVLY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1408
JUND	ENCODE Transcription Factor Targets	1.0	null
IGFBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25125
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928737
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45324
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22946
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147240_3_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79329
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84675
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25463
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4077-01B-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01461
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0418
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899574
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.08
Prostate adenocarcinoma_PRAD_TCGA-HI-7170-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.31169
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919576
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39635
KIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05881
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88919
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8399
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.827583
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871434
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05556
GARIN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0548
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37864
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829848
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21171
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TF-04-RX73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.712241
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6031-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.356838
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SO-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14893
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.09038
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5678
u138mg	HPA Cell Line Gene Expression Profiles	1.0	1.40692
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.882749
GTEX-XPT6-0326-SM-4B66V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11913
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.09989
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
Pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02093
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4826
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00904
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
hsa-miR-518a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
r6 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84928
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861908
HD-29-PZ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209407
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21909
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01556
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46241
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.33
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956441
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37541
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MB-15-ZF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.533693
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of primary metabolic process	GO Biological Process Annotations 2025	1.0	null
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7891
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208486
TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32143
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01452
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17312
496100607_TCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48964
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of glycogen biosynthetic process	GO Biological Process Annotations 2015	1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	3.49226
GSE198165,GSE198166_7_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AE-88-WQ63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371243
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41744
THP1	DepMap CRISPR Gene Dependency	1.0	2.87146
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2942-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-30-CR11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.486918
QB-72-LM87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278471
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13407
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MA-31-VM30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207215
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51201
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34834
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10205
decreased white adipose tissue amount	MGI Mouse Phenotype Associations 2023	1.0	null
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208554
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08086
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03616
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13206
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14746
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GE-29-ZM45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.985923
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.80102
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290803
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58446
LN443	CCLE Cell Line Gene Expression Profiles	1.0	1.35725
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2418
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828092
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25459
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993564
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44664
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04339
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14154
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0669
CHP-126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3761
DICER1_Deficiency_GDS3685_518_mouse_Hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.42263
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.25778
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37775
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7108
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835732
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51198
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955681
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31792
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52967
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2193
HS695T	CCLE Cell Line Gene Expression Profiles	1.0	1.64242
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05684
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89792
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17894
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-3026-SM-3NB1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1435
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.862408
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52944
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.907958
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664553
PHF8	ENCODE Transcription Factor Targets	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952202
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07587
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385371
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4438
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05966
REST	ChEA Transcription Factor Targets	1.0	null
GTEX-XOTO-0226-SM-4B66H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14278
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.79119
positive regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898336
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.6767
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874133
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3074-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
positive regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
RPS6KA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30945
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48362
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00206
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
hsa-miR-4772-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
mantle zone of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40114
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.72654
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38523
Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-46-FO63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211338
MRPL57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00591
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.611567
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38153
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367863
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47179
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932069
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40815
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
TB-06-VB30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312137
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
S0-EE-YEKU_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471554
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16677
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30246
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245569
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
increased circulating free fatty acids level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49067
FAM236B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47945
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39095
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77795
USF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEx Uterus 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-3.91115
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94808
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57526
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933364
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884489
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.78387
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55215
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35106
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15378
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030793
KA-72-WY22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27219
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934597
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568811
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.916321
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62855
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KB-92-MK13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381386
GTEX-R55G-0626-SM-48FDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37637
MAZ	ENCODE Transcription Factor Targets	1.0	null
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14046
CDC14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12315
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16407
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272279
CB-87-RB49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277965
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27287
liminal part of r4 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64932
NCIH2286	DepMap CRISPR Gene Dependency	1.0	3.67846
GTEX-T6MN-1126-SM-4DM71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92838
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987111
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.40829
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WM3772F	DepMap CRISPR Gene Dependency	1.0	10.4349
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12296
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04452
AC-75-CE67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.657863
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13276
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39521
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991517
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17661
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02611
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.942718
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
protein oligomerization	GO Biological Process Annotations 2015	1.0	null
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02177
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53742
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28415
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91895
HD-19-IW09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263584
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUW1-1126-SM-4BONZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966101
FZD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52973
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01983
Rb-E2F complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
NB13	DepMap CRISPR Gene Dependency	1.0	4.30082
JD-62-TK68_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251495
SPI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPN-2826-SM-3LK67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08062
GTEX-P4PP-3026-SM-3P61O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965343
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884489
GTEX-QCQG-1526-SM-48U25	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976086
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955155
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1932
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978209
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.569041
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28626
Acute Myeloid Leukemia_LAML_TCGA-AB-2901-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943529
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.06114
BA-39-HG26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.506945
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6980-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4776-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975771
lymph node	HPA Tissue Gene Expression Profiles	-1.0	-0.859148
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7488
DLX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23527
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.600374
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.8768
Kmp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
wm115	HPA Cell Line Gene Expression Profiles	1.0	1.09331
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4713-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.55876
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.605374
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829848
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CC-31-VS31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.64495
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12299
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.793558
Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VH-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-0726-SM-4AD6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81123
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04355
regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.126885
Lung epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03597
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23974
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OQ-11A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36934
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10248
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30215
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893573
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71516
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CE-15-YU05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345681
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.314488
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.16044
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0373
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46839
CORL51	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78981
Bony labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.091153
SC-72-YW56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30502
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.20252
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952202
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27656
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7057
intermediate stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07136
CHD2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
19605494-TableS1	GeneSigDB Published Gene Signatures	1.0	null
OCIMY7	DepMap CRISPR Gene Dependency	1.0	3.18946
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46902
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46431
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278373
ND-86-GT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235391
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09194
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CA-66-YB17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430358
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trans-Golgi network transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49033
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0541
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927405
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.643501
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
BECKER	CCLE Cell Line Gene Expression Profiles	1.0	1.48213
hsa-miR-2467-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57892
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15561
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66837
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03298
SCLC21H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7826
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64831
hsa-miR-519e	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04195
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08385
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
WDR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29356
SNU620	DepMap CRISPR Gene Dependency	1.0	2.13431
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31316
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00348
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15284
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73941
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE67266_2_v_1_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880417
GSE205963_0_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RNOR-1326-SM-48FDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868747
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4795-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0426-SM-3TW8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05639
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4345-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ZNF713	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51279
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869103
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	6.35653
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68686
EGR1-19032775-M12-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48615
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255424
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6907
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03754
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL311	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36225
positive regulation of kinase activity	GO Biological Process Annotations 2015	1.0	null
decreased respiratory quotient	MGI Mouse Phenotype Associations 2023	1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.00687
JE-55-OJ53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436865
NB-80-IM48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254364
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94066
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25572
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952202
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23116
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39167
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321632
superficial stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55993
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17048
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8298-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85157
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ETNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33914
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN18_KO_GDS4961_28_mouse_whole lung tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03538
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59187
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03563
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15277
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35276
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871815
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04208
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976653
YA-44-LW45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18758
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.1091
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49H-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of protein serine/threonine kinase activity	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.05335
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88261
EGR1	ChEA Transcription Factor Targets	1.0	null
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.937606
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09076
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33444
COLO741	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56184
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07535
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24577
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.539552
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33165
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05347
Muscle tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5778
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD-YAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
HE-16-PO98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257001
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14935
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VL-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.23616
hsa-miR-670	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257945
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6397
KDM5A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1248	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147240_3_v_1_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27287
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of mapk cascade	GO Biological Process Annotations 2015	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69073
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35364
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852905
PMC6459557-pbio.3000201.s012.xlsx-Sheet1-FOXD1_FOXD1	Rummagene Transcription Factor Associations 2026	1.0	null
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481781
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10398
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.3494
BA-68-FJ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.462775
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.040999
GTEX-VJYA-0226-SM-4KL1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74718
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70281
RBPJ	ChEA Transcription Factor Targets	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976653
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
253J	DepMap CRISPR Gene Dependency	1.0	4.8578
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.416924
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37779
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78672
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
EFO-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.38715
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895414
activation of protein kinase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
DC-17-ZB19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.520531
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11099
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14257
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27437
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4258	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71188
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72945
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.949
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.6064
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92489
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06526
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.18844
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02767
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45379
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24835
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.89371
PU-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02214
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05162
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866908
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893621
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.54025
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83739
NCIH196	CCLE Cell Line Gene Expression Profiles	1.0	1.6938
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0888
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48943
1321N1	CCLE Cell Line Gene Expression Profiles	1.0	1.88966
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.99918
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.773599
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04099
medial group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10599
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1163
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968048
ANAPC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57606
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162688_1_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
positive regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19656
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1341
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64001
A-Vietnam-1203-2004(H5N1)_7Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45387
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18227
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26389
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_TUBA1A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FD-79-TC61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.452915
IPO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22091
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.638315
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.2531
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844428
hsa-miR-4659b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56371
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.952173
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.669647
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33175
AD-58-PW17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271331
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.907579
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37492
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53186
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.560164
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24141
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0427
GSE179002_2_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21524
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE212628_6_v_1_mier1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09696
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DD-74-PJ26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371794
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.38671
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00253
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
SKMEL24	DepMap CRISPR Gene Dependency	1.0	3.27041
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06029
AD-86-OB87_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245772
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55048
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54548
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72542
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
mRNA_SMAD4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883644
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
POU5F1_01_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.27684
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7821
C22orf23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20176
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851752
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.74239
binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of kinase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0529
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1145
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64471
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451959
ECT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3968
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38213
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.17268
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81321
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53315
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08497
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64832
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226195
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.8688
hsa-miR-5095	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29297
nfe2l2_23639809_whole_esophagus_lof_mouse_gpl7202_gse39629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.270057
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06367
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34982
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3261
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0227
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41477
hsa-miR-4418	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
AA-94-TU18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418412
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99641
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06497
Perturb_11872_KO_lincRNACox2_SRP120127	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.41527
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43074
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.806328
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55993
HA-32-YH61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.654436
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64932
activation of mapk activity	GO Biological Process Annotations 2015	1.0	null
NHEM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.471
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S0-EE-Y97N_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.589096
Complement component C1q complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.297
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.65
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28883
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7291
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09595
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
AA-48-XT80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280271
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933285
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2386
hsa-miR-515-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.501125
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.72235
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-3026-SM-3MJGS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913383
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9425
EGR1-19032775-M12-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04075
GTEX-PSDG-0826-SM-48TCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958273
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0938
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9869
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07887
CD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01875
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32446
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76499
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244958
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914158
KC-32-GO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.528154
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77393
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379499
periventricular stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60348
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.54186
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18342
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.28097
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.921665
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.605006
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05162
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
r7 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22406
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.876336
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U138MG	CCLE Cell Line Gene Expression Profiles	1.0	1.44877
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BE-17-CS60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742992
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4664-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13852
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04379
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35276
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90483
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444881
PPP1CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97212
r4 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55993
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5O9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKLU1	CCLE Cell Line Gene Expression Profiles	1.0	1.95749
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK11IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82033
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
MUC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41411
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39278
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0305
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305997
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960035
increased carbon dioxide production	MGI Mouse Phenotype Associations 2023	1.0	null
AE-52-NW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.579939
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.502218
IZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889316
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459199
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4982
CNTROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44938
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59181
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21168
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.464168
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
posteroventral (inferior) parietal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37243
AF-11-IL39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221308
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09078
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990903
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558526
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2392
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.38217
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84739
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SQSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.21527
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05784
BE-92-TW08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.602093
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02268
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.094
DE-98-FC24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.904056
JB-74-LF71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249196
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-27-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.595164
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00779
positive regulation of glucose transport	GO Biological Process Annotations 2015	1.0	null
DF-92-CF17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264151
ZNF263	ENCODE Transcription Factor Targets	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.89193
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53051
Myositis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836461
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SB-28-EJ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.68177
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-O5YW-3026-SM-3MJHI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971556
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8381
Perturb_8809_KD_FLNA_SRP318361	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE149760_3_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19363
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.832811
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73343
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61427
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51865
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00451
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06142
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4784-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54608
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.474647
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of lipid metabolic process	GO Biological Process Annotations 2025	1.0	null
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.941881
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-02-XL81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01553
mantle zone of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33113
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06289
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14218
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.875568
AD-86-OB87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281515
GTEX-U3ZN-2526-SM-3DB7V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09356
CC-03-PW00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.443274
Acute Myeloid Leukemia_LAML_TCGA-AB-2870-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26824
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3737
C1orf198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36986
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57836
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48745
r4 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07136
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
B3GNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00777
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0572
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04922
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20071
Fetal Lung	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.13989
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938684
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53426
regulation of glycogen biosynthetic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-1126-SM-4E3I1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59786
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4052
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836881
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.957764
Lung adenocarcinoma_LUAD_TCGA-73-4676-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3975	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851752
BE-04-AN21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10332
CF-48-QD87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244769
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.103
SRSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45751
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33497
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13038
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41993
VA-06-DB75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354228
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6892
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75509
regulation of glucan biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Fra-1_KO_GDS5078_402_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COR-L32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896795
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30851
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41744
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESRRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30949
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54207
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11871
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52099
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40394
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855266
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896365
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995227
ATM_knockout_75_GSE23116	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.49451
HL-7702 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KBTBD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04525
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LN229	CCLE Cell Line Gene Expression Profiles	1.0	1.53826
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.899661
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.997281
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SUM1315MO2	DepMap CRISPR Gene Dependency	1.0	2.77834
KA-71-CQ35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226573
MITF	ChEA Transcription Factor Targets	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2806
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439502
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.69602
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.966732
AC-75-LR63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278853
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00903
GCT	CCLE Cell Line Gene CNV Profiles	1.0	1.49286
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71132
YA-85-VH07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224133
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851979
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-339-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
hsa-miR-3135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55319
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WM-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59125
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
59M	DepMap CRISPR Gene Dependency	1.0	4.58256
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25053
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872334
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16339
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
positive regulation of glycogen metabolic process	GO Biological Process Annotations 2015	1.0	null
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TF-04-RX73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311141
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1616
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840928
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
FA-80-DR66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.61397
HPAFII	DepMap CRISPR Gene Dependency	1.0	4.70979
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16598
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97848
artery disease	GWASdb SNP-Disease Associations	1.0	0.091212
PMC9811786-13148_2022_1394_MOESM17_ESM.xlsx-SKI-Stress_CpG_gene_SKI	Rummagene Transcription Factor Associations 2026	1.0	null
C5orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12092
MOLP8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77037
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.631
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274067
SPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48728
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
RB-55-KL42_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232754
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.591932
CB-13-ZM96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201301
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75212
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.448
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37963
FOXO1_KD_GDS2720_477_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
p3 part of the ZL core	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15284
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00426
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	2.93359
NCI-H2029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42127
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842834
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.50109
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.46107
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BB-20-UU03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206081
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.48593
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00413
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.849
GTEX-UJHI-0926-SM-4IHKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926223
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160293_2_v_4_celf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SA-53-XG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.709732
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_5409_KD_PLZF_SRP136521	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.33936
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93394
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.699903
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837713
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.889187
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63241
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28041
positive regulation of transferase activity	GO Biological Process Annotations 2015	1.0	null
Weight loss (gastric bypass surgery)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
CALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15333
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
QA-14-AU91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325782
RC-K8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sarcoma_SARC_TCGA-DX-A3LW-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910111
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4917
GTEX-U3ZN-0526-SM-4DXTH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80808
KLHL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4231
H2BK120ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PD-26-DC63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.59304
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8935
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64932
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91859
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35883
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39841
MATN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07547
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0259
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0549
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67497
Perturb_16081_KO_Myf6_SRP212302	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.86751
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364571
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of glucose transport	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-518f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.478
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54002
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POSTN_01_293	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.7292
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24464
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31079
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.496971
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MSTN_KO_GDS3637_439_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45178
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
CAOV3	CCLE Cell Line Gene Expression Profiles	1.0	2.13624
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99115
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77917
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9104
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GDPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6012
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CC-03-PW00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245596
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957506
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68788
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942127
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69273
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40797
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84805
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2114
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.954668
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25541
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0208
hsa-miR-4659a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0326-SM-4JBIY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61612
regulation of protein kinase activity	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8394-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Presubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26182
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268406
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39327
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.775571
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
increased oxygen consumption	MGI Mouse Phenotype Associations 2023	1.0	null
DE-73-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.535668
BE-17-CS60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319351
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4013
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
m1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00451
GC-46-CA74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11017
GTEX-OOBK-0425-SM-3LK5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1663
PMC5986551__F5	PFOCR Pathway Figure Associations 2023	1.0	null
FBXO42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33855
Superior central nucleus raphe, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00451
KB-78-BE93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291638
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HYCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49202
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32073
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8538
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2258
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60788
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47493
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JB-60-JM38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229253
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258409
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.46498
positive regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
BANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2063
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928162
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6398
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851532
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27081
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PCNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43415
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.9637
NA-16-OJ70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51709
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.431219
NAXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25009
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.846682
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52907
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347802
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80227
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4760-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217694_3_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FD-48-HZ39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.45388
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PC-62-AQ92_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252263
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2826-SM-4BOQ2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905912
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.996024
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
17682054-Table1	GeneSigDB Published Gene Signatures	1.0	null
AC-35-CK01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378603
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35897
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.98676
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07039
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CC-90-NK44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384007
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3638
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.986492
BB-42-FF52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330278
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84125
TFEB	ChEA Transcription Factor Targets	1.0	null
protein complex	GO Cellular Component Annotations 2015	1.0	null
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06188
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90131
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90865
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-2_E2F1-Gene_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
OARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59453
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40114
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49833
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.75675
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.92129
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.24487
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872503
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
A375SKINCJ2	DepMap CRISPR Gene Dependency	1.0	3.56032
RNF2	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8127
SKRC20	DepMap CRISPR Gene Dependency	1.0	8.4098
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.442
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06079
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55321
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940417
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6403-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Subceruleus nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04222
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.983241
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832909
GSE221004_3_v_0_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11669947-JCSM-16-e13672-s001.pdf-93-GLIS3_GLIS3	Rummagene Transcription Factor Associations 2026	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.75231
8305C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein heterooligomerization	GO Biological Process Annotations 2015	1.0	null
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33827
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.62317
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10561
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11604
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3179	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71553
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995395
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06342
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96248
biological regulation	GO Biological Process Annotations 2015	1.0	null
PNKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63566
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of cellular carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17309
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
CCNI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54243
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.69285
increased basal metabolism	MGI Mouse Phenotype Associations 2023	1.0	null
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76894
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924805
AF-67-LZ82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397672
positive regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39474
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11441
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31996
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37763
RH41	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90313
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3415
H3K27me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25352
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JF-30-FW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.840405
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278622
DC-61-QV78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267436
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.839609
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of map kinase activity	GO Biological Process Annotations 2015	1.0	null
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326439
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-27-BW20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.677363
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3925
PMC3371315-NIHMS350140-supplement-8.xls-MCF7-T47D-SK-453_Down_MCF7-T47D-Supplementary_Table_1_ER-positive_FOXA1_signature_Genes_decreased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.539
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of transport	GO Biological Process Annotations 2015	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
regulation of cellular ketone metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-518c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53308
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
DA-81-VY50_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.949641
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.633935
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE190555,GSE190557_2_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41059
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.19944
SP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78782
AB-85-JR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233246
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1206
PMM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80291
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374604
HE-16-PO98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413445
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03754
NFIX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48184
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10028
mRNA_ATF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01286
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18735
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35276
DC-51-WE27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223664
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00451
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35255
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909499
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33403
PC-68-DU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.643821
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AA-99-PN83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.868864
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44611
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05002
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-XUYS-0426-SM-47JX3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28535
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-193b-3p	MiRTarBase microRNA Targets	1.0	null
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12647
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875887
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
LARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20766
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JE-22-JR20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286579
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C6-06A-12R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
eomes_23431145_e14dot5_neocortex_lof_mouse_gpl6246_gse43387	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.61262
GSE133213_10_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28921
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61627
IGR39	CCLE Cell Line Gene Expression Profiles	1.0	2.04726
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53639
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9286
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00835
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852905
increased energy expenditure	MGI Mouse Phenotype Associations 2023	1.0	null
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05162
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12228
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8372
A-VN-1203-2004(H5N1)_Day1-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.55657
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10686
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49946
regulation of transport	GO Biological Process Annotations 2015	1.0	null
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00965
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	1.0	3.22603
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991296
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30337
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12623
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LA-10-VZ79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208206
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46826
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45526
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.64955
Sarcoma_SARC_TCGA-DX-A6BE-01A-41R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28664
GSE147240_3_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.76874
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_upreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ND-68-CU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226825
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15048
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75509
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8313
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27474
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PGRMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61685
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
BC-15-EL49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.878975
FE-29-XM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10673
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2387
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2961
CREB1_01_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.42678
CA-68-TC79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01104
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18055
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23611
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3537
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952202
hsa-miR-1254	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27437
ATF3	ENCODE Transcription Factor Targets	1.0	null
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25157
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3494
regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0426-SM-4B66A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36564
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58643
PF-59-CY33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248543
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
bone disease	GWASdb SNP-Disease Associations	1.0	0.161444
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12001
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.853265
CB-02-XL81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223844
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75509
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64554
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.53552
BB-20-UU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241013
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258765
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03617
positive regulation of glucose metabolic process	GO Biological Process Annotations 2015	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58128
abnormal phospholipid level	MGI Mouse Phenotype Associations 2023	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.2549
AMOTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38778
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990943
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837882
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06045
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YF-00-IN39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.634861
GTEX-XQ8I-1326-SM-4BOPV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21635
GTEX-P4QS-0426-SM-3NMCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52322
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64471
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06123
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0626-SM-4AD6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36308
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56879
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830828
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21734
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888025
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55369
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18876
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64772
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JB-23-ZE86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304148
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46166
JC-02-ZR15_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22634
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464481
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
KMRC20	DepMap CRISPR Gene Dependency	1.0	2.52058
TMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21365
intermediate stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35276
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256857
Perturb_11695_Mut_HRAS_SRP278399	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90862
ST486	DepMap CRISPR Gene Dependency	1.0	3.29349
496100557_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16875
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324563
regulation of glycogen metabolic process	GO Biological Process Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13076
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATPAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18833
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypertension	GWASdb SNP-Disease Associations	1.0	0.532547
DE-30-UR76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298223
r3 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84928
RBM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77158
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28431
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.154406
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-0.944524
FUCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24288
AC-28-RT00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331973
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.95786
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41108
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-28-SS67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211702
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205754
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.25778
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.57855
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85091
intermediate stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08265
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07362
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23845
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.94135
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11627
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	2.47111
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40733
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.9839
DD-01-VE87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269118
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9644
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98615
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46033
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965321
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.229
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-5_Comparisons-FOXM1_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13099_OE_Dux_SRP220068	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.30314
DD-74-PJ26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21559
NRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11434
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12109
NAGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41101
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76894
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
8505C	DepMap CRISPR Gene Dependency	1.0	3.43676
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.888111
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HO-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.749571
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17113
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trans-Golgi network transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14139
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.89402
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.35739
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AE-51-ZO26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.881416
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.32066
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80365
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60348
hsa-miR-342-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12801
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960197
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77852
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.624
RARA_01_51	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.28688
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247527
hsa-miR-3129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13403
icSARS CoV_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.32476
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	3.33699
regulation of glucose import	GO Biological Process Annotations 2015	1.0	null
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86488
POLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8369
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16434
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17237
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NB-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12896
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CB-02-XL81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36615
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GD-82-CS38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.516758
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
KDM4A	ENCODE Transcription Factor Targets	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.936959
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78685
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
CC-18-YW57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234927
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.748601
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968331
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65476
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43185
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.58975
LASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76543
KDM5B	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29363
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03591
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66838
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941171
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
decreased cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.589624
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316536
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.513511
LN428	DepMap CRISPR Gene Dependency	1.0	3.5408
GOLPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53205
protein trimerization	GO Biological Process Annotations 2015	1.0	null
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7141
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.52303
TGFBR2_knockout_295_GSE45968	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.62621
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.716354
Melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13327
intermediate stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84928
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0046
AD-00-WA10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.55181
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32562
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35089
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8482
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.748
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3591
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67026
Supratrigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27437
GSE213219_2_v_3_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390682
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NPIPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50428
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H9c2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
hsa-miR-518d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80631
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
disease	GWASdb SNP-Disease Associations	1.0	0.02821
hsa-miR-656	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07105
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04598
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
biological_process	GO Biological Process Annotations 2015	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85551
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95688_7_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3688
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22406
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04222
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
BB-44-SX65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270953
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00452
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
RD-50-EO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229703
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903191
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.79541
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Chondrocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.32065
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
143B	DepMap CRISPR Gene Dependency	1.0	2.80791
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BV-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4720-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
KMRC2	CCLE Cell Line Gene CNV Profiles	1.0	1.52023
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0926
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.52099
MF-37-KQ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418237
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06092
HMGN3	ENCODE Transcription Factor Targets	1.0	null
KB-78-BE93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257813
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841874
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.02862
Arnt::Hif1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7019
Vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
CA-25-LR28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204499
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17036
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 1 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11366
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36294
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8877
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919273
regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62849
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03586
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82037
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42868
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849359
Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91964
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42413
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_14_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of protein kinase activity	GO Biological Process Annotations 2015	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9441553__F5	PFOCR Pathway Figure Associations 2024	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.30045
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04577
GTEX-Q734-2226-SM-3GAD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2134
OV7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49075
CAL148	CCLE Cell Line Gene Expression Profiles	1.0	1.87049
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74213
proteinaceous extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
KA-63-FH23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256424
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.944524
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.493895
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.608401
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1361
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04385
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833994
PRORP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84699
NRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66717
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03022
hsa-miR-3167	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-XUZC-0626-SM-4BOPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27343
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.6516
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56922
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-2126-SM-4JBJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19608
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07028
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95072
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944054
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70212
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
QA-34-PH05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215581
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13021
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45523
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901422
AE-32-DP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286957
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02555
GPR89A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92025
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6777-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.979856
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906866
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41625
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23785
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76036
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.171532
ZNF460	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4844
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8483
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61244
GSE67266_7_v_1_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8085
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25829
periventricular stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00451
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35791
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5742
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8544
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56053
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.927
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837888
XB-53-OZ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.927255
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52928
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1317
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279525
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35276
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.378748
Perturb_16080_KO_Myf6_SRP212302	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58339
rh30	HPA Cell Line Gene Expression Profiles	1.0	1.83192
Muscular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
Rheumatic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.462
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.63391
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10231
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961859
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49379
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2592
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.544099
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863404
H357	DepMap CRISPR Gene Dependency	1.0	4.25307
HS675T	CCLE Cell Line Gene Expression Profiles	1.0	1.77609
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869959
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828961
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08642
ENTPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46569
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947428
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13327
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0426-SM-3NM91	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911021
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26288
PMC4021255__F3	PFOCR Pathway Figure Associations 2024	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4420	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4802-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11703
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13409
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07136
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-47-YZ27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292264
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-83-LN99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.465741
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41357
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851009
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58853
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07136
r6 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37564
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DE-69-QQ25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274417
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46305
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80513
FB-98-HM88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21853
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
Lung adenocarcinoma_LUAD_TCGA-49-6743-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48643
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12398
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.57514
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.745992
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4167
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.15
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72971
SIN3A	ENCODE Transcription Factor Targets	1.0	null
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46146
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46597
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946202
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325775
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02283
GTEX-PX3G-0726-SM-48TZT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988853
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9899
HS229T	CCLE Cell Line Gene Expression Profiles	1.0	1.49542
molecular_function	GO Molecular Function Annotations 2015	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59783
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40431
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.527591
positive regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6561
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88166
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ID-90-NM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26607
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13193
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.945287
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0987
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4098
GSE179002_2_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.94995
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3449
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0991