association dataset threshold value standardized value H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49226 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CHTOP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24802 PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null maturity-onset diabetes of the young type 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.02 STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null glucose metabolism disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 1.35663 GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.14942 r9 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02628 Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48836 hsa-miR-520c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 cellular component organization or biogenesis GO Biological Process Annotations 2015 1.0 null GSE181517_2_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38294 MYL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4111 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.987587 COLO741 CCLE Cell Line Gene CNV Profiles 1.0 2.15092 DMRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7295 PMC11781671-ppat.1012897.s015.xlsx-Tab_S1-S1_Table_The_detailed_information_of_DEGs_in_Huh7_cells_post_MSX1_overexpression_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null EYA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79468 Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.08263 H3K27me3_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13219 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A822-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC26A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05019 MALME3M DepMap CRISPR Gene Dependency 1.0 4.8158 PHLDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41594 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85109 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cohen syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.338 GTEX-S4P3-0626-SM-4AD59 GTEx Tissue Sample Gene Expression Profiles 1.0 0.973153 CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SLC17A9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45532 superficial stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75198 SIN3A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior pretectal nucleus, dorsal core part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5183 CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.43106 ADAMTS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53493 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4647 Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.952 GSE219103,GSE219104_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PXYLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07376 H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Intestine TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Anteroventral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04501 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RTLS-2626-SM-46MUJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.932668 GSE183413_1_v_2_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6665 KLF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32364 SLC5A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38869 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1337 H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFF ENCODE Transcription Factor Targets 1.0 null membrane fusion GO Biological Process Annotations 2015 1.0 null r4 part of descending trigeminal sensory nucleus, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51709 PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG Rummagene Transcription Factor Associations 2026 1.0 null FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.357 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4555 hsa-miR-3185 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 intermediate stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01591 hsa-miR-3118 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE118617,GSE118619_0_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25174 Lung adenocarcinoma_LUAD_TCGA-55-6979-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRKDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54676 POGLUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80027 PSMB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07909 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32692 ACKR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31968 CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 LYPLA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47815 CCT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42327 GSE122425_1_v_0_nsun2_human RummaGEO Gene Perturbation Signatures -1.0 null Central amygdalar nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18872 ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3591-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 FAM83G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12199 organelle LOCATE Curated Protein Localization Annotations 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null QRICH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27235 CTCF_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null C1QTNF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06698 ZNF837 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56669 JARID2-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GEMIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67732 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JARID2 ChEA Transcription Factor Targets 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERG_01_17 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.21878 terete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75354 Primary somatosensory area, upper limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10035 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null RT4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966707 CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6659 GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.36852 biological_process GO Biological Process Annotations 2015 1.0 null PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null ZNF677 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46827 OVMANA CCLE Cell Line Gene Expression Profiles 1.0 2.46467 GTEX-RM2N-1926-SM-48FCU GTEx Tissue Sample Gene Expression Profiles 1.0 1.62019 cell part GO Cellular Component Annotations 2015 1.0 null UMRC6 CCLE Cell Line Gene Expression Profiles -1.0 -1.55614 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0227 positive regulation of acute inflammatory response GO Biological Process Annotations 2023 1.0 null BLOC1S4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33878 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.745 Pancreatic agenesis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.204 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SNX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11132 RPRD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93819 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRICKLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62038 CD164L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04168 CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QS-1126-SM-3NMD5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23704 TERF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59294 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.97094 GTEX-REY6-1226-SM-48FDR GTEx Tissue Sample Gene Expression Profiles 1.0 1.18564 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null 496100494_HIP_no dementia_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.82362 vesicle-mediated transport GO Biological Process Annotations 2015 1.0 null E2F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55058 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74565 GTEX-TKQ2-1726-SM-4DXUP GTEx Tissue Sample Gene Expression Profiles 1.0 0.855656 Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-1026-SM-3NMCN GTEx Tissue Sample Gene Expression Profiles 1.0 0.841948 SETD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.58792 GTEX-S33H-1826-SM-4AD65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45628 interanterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11169 NCIH727 CCLE Cell Line Gene Expression Profiles 1.0 2.54201 cerebellar nuclei of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32122 hsa-miR-548e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 KLHL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65758 acquired metabolic disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.835734 single-organism transport GO Biological Process Annotations 2015 1.0 null SAC3D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55826 PAT complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.535 PODXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22438 GTEX-WWYW-0926-SM-3NB2Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.968727 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.917411 TP53-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null Nerve Degeneration CTD Gene-Disease Associations 1.0 1.01625 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1723 GTEX-T6MO-1426-SM-4DM73 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03869 CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057445 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TBK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13388 POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bed nuclei of the stria terminalis, anterior division, oval nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88224 disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.505739 GSE199255,GSE199356_3_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Striatum ventral region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07774 BL1705 (PHB2) NURSA Protein Complexes 1.0 null Cardiovascular Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null FAM216A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95011 FGF22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71699 CTCF ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KC-A4BN-01A-61R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A1207 CCLE Cell Line Gene CNV Profiles 1.0 1.34786 Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARSI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42989 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.930103 Primary somatosensory area, lower limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88565 USF2 ENCODE Transcription Factor Targets 1.0 null hsa-let-7a-5p MiRTarBase microRNA Targets 1.0 null superficial stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40329 CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC25A38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84604 GSE148692,GSE148695_7_v_0_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3778 E2F6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RUSQ-0226-SM-47JWT GTEx Tissue Sample Gene Expression Profiles 1.0 1.1399 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SHKBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28904 periventricular stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2624 CNPY3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42252 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.5413 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.923 forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054395 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27275 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12583 Prelimbic area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18389 inner CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.861735 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15257 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.877326 MAVER1 DepMap CRISPR Gene Dependency 1.0 5.30008 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966707 RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null carbohydrate metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.572662 GATAD2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84167 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC26A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18956 ETS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9301 inner SZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07967 GATA1 ENCODE Transcription Factor Targets 1.0 null REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles 1.0 1.04366 BACH1 ENCODE Transcription Factor Targets 1.0 null PRR35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4966 ERA-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE172016_2_v_5_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH1963 CCLE Cell Line Gene CNV Profiles -1.0 -2.16624 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2025 1.0 null CYTH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25375 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TWIST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32192 GSE134615_1_v_0_lats1_human RummaGEO Gene Perturbation Signatures -1.0 null SNU719 CCLE Cell Line Gene Expression Profiles 1.0 1.91943 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72059 ENO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08569 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35785 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02181 H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPN-0011-R3A-SM-2I5FC GTEx Tissue Sample Gene Expression Profiles 1.0 1.36305 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LSM12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55621 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.0359 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32594 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14689_KO_Ffar3_SRP057302 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 establishment of localization GO Biological Process Annotations 2015 1.0 null A-VN-1203-2004(H5N1)_Day2-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.03859 CTCF_GM12870_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPK-1526-SM-3MJGM GTEx Tissue Sample Gene Expression Profiles 1.0 1.2527 liver_d HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09482 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null p1 part of the substantia nigra reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09571 CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MT-ND4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12654 MXI1 ENCODE Transcription Factor Targets 1.0 null hsa-miR-3688-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09791 H3K27me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GUCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4847 RNF20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63713 critical GeneRIF Biological Term Annotations 1.0 null TMEM115 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61758 GTEX-XBED-0226-SM-47JY8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57186 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54907 TM6SF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09518 RPS6KA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02518 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.936446 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.03519 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.3724 AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4EP-0626-SM-3P621 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26895 H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FKBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55283 hsa-miR-4778-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.053794 ZNF446 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6404 Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEL270 DepMap CRISPR Gene Dependency 1.0 3.84205 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.86859 YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.039 GSE151494_1_v_9_nrp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3607-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GSE245134_2_v_3_atg5_mouse RummaGEO Gene Perturbation Signatures -1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70I-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE116299_6_v_5_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null Hyperglycemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.355 GTEX-OIZH-2026-SM-3NB1M GTEx Tissue Sample Gene Expression Profiles 1.0 1.05368 GSE207787_3_v_2_pdha1_human RummaGEO Gene Perturbation Signatures -1.0 null MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC Rummagene Transcription Factor Associations 2026 1.0 null H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 647V CCLE Cell Line Gene CNV Profiles 1.0 1.64929 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OE19 CCLE Cell Line Gene Expression Profiles 1.0 2.2438 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null YTHDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42438 GSE207582_4_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07256 PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR Rummagene Transcription Factor Associations 2026 1.0 null nuclear lumen GO Cellular Component Annotations 2025 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49185 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SYT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83302 MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE184210_0_v_3_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.935538 Lung adenocarcinoma_LUAD_TCGA-62-8402-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE108614,GSE108615_3_v_2_setd1a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lateral reticular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74679 hsa-miR-106b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GTEX-S3XE-1026-SM-4AD4O GTEx Tissue Sample Gene Expression Profiles 1.0 1.0145 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46617 TAGLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64263 17344918-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null HCC1806 CCLE Cell Line Gene CNV Profiles -1.0 -2.09653 ZNF384 ENCODE Transcription Factor Targets 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE227592_13_v_3_adar_human RummaGEO Gene Perturbation Signatures -1.0 null RALBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53416 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 624 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14436 hsa-miR-3977 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 TERT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31731 Perturb_6669_KO_FGFR3/FGFR4_SRP386785 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.56301 REST_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPL-1626-SM-2HMIR GTEx Tissue Sample Gene Expression Profiles 1.0 0.885654 septostriatal part of the olfactory tuberculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06101 BHLHE23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35739 regulation of acute inflammatory response GO Biological Process Annotations 2025 1.0 null REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FADS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8216 STAT1_KD_GDS4754_159_human_JURKAT GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.71824 TNFRSF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41798 GTEX-WHSE-0011-R8A-SM-3P5Z1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18377 GSE212074_0_v_1_pus1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE158834_7_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null CDX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3395 ZBED1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1861 TPGS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62852 ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1531 GSE57871_11_v_9_vorinostat_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ETV4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4712 Ventral anterior-lateral complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44665 RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE188869,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98484 UM-UC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22992 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adipocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.818 CORL311 CCLE Cell Line Gene CNV Profiles -1.0 -1.66864 Colon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03752 SREK1IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11414 LS 174T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22104 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.07957 PLC/PRF/5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.942815 PPP1R16A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64018 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.881458 hsa-miR-302a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 PMC6433273-pone.0214296.s009.xlsx-Table_C-S3_Table_Differentially_expressed_mRNAs_in_human_primary_monocytes_after_6_hours_of_LPS_stimulation_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Anterior cingulate area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0392 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 1.64 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL4W-0011-R8a-SM-2I3G4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36133 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10296 NCIH211 CCLE Cell Line Gene CNV Profiles -1.0 -1.58538 snare binding GO Molecular Function Annotations 2015 1.0 null CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCFL ENCODE Transcription Factor Targets 1.0 null TFEB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4503 GTEX-Q734-0426-SM-48TZX GTEx Tissue Sample Gene Expression Profiles 1.0 2.00615 Lung adenocarcinoma_LUAD_TCGA-44-8119-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Type 2 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.058 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GR MotifMap Predicted Transcription Factor Targets 1.0 null COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979515 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051121 ARID3A ENCODE Transcription Factor Targets 1.0 null H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null metal ion binding GO Molecular Function Annotations 2015 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.868527 Tuberomammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10616 ACTR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54897 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050992 membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null single-organism localization GO Biological Process Annotations 2015 1.0 null hsa-miR-29b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 USP2_KO_GDS5079_25_mouse_kidney GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ENSG00000230707 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36834 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.841563 TP53-22127205-IMR90-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.54944 EFNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24505 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1 Rummagene Transcription Factor Associations 2026 1.0 null POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WEY5-1226-SM-4LMIQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.74175 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null nucleus GO Cellular Component Annotations 2023 1.0 null NCIH1339 CCLE Cell Line Gene CNV Profiles 1.0 2.47014 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null P2URK562 DepMap CRISPR Gene Dependency 1.0 2.64837 PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PWCY-1426-SM-48TCT GTEx Tissue Sample Gene Expression Profiles 1.0 0.939424 Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20435 ITFG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46308 HCFC1 ENCODE Transcription Factor Targets 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041233 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null FAM83E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85374 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5334-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12875_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nucleus of the solitary tract, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16261 TTC31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19004 r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.68 GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 3.33309 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LRP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55914 HCC1833 CCLE Cell Line Gene Expression Profiles 1.0 2.15253 RAB4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60698 neurotransmitter transport GO Biological Process Annotations 2015 1.0 null parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 4.34743 Perturb_14556_KO_KLF5_SRP051606 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null B3GNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7156 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SHISA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.16347 MRPL20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8438 RAJI DepMap CRISPR Gene Dependency 1.0 2.08929 CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_563_KD_MYCN_SRP158473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.4573 IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9276 Insulin-related traits (multivariate analysis) GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.2699 NPIPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68293 GSE239844_8_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null HEATR5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19151 Johnston's organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.778 H3K36me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YW-1526-SM-3MJGL GTEx Tissue Sample Gene Expression Profiles 1.0 0.985577 single-organism organelle organization GO Biological Process Annotations 2015 1.0 null NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.59942 SLC6A9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7807 GSE207582_2_v_1_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QEL4-1226-SM-447A4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.84727 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-199b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 hsa-miR-29a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 SEMA4F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88463 Perturb_2485_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04711 GSE121824,GSE121826_0_v_8_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FEV JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7554 H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TP-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ECC4 DepMap CRISPR Gene Dependency 1.0 7.59971 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.597296 MLF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53728 c-Myc MotifMap Predicted Transcription Factor Targets 1.0 null ARID3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11085 GTEX-RWSA-1426-SM-47JXA GTEx Tissue Sample Gene Expression Profiles 1.0 1.48747 RPMI2650 DepMap CRISPR Gene Dependency 1.0 2.63082 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null STK26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17161 Primary T cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -2.0876 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XXEK-1226-SM-4BRUY GTEx Tissue Sample Gene Expression Profiles 1.0 1.91639 GTEX-PWOO-0726-SM-2I3EB GTEx Tissue Sample Gene Expression Profiles 1.0 0.860625 GSE116299_6_v_1_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null CTCF_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BMI1-23680149-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null stress fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.216111 NUDT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2198 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null layer 2 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83559 GSE137914_0_v_3_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE246576,GSE246826_2_v_1_dapagliflozin_mouse RummaGEO Drug Perturbation Signatures 1.0 null nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CTCF_GM12873_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.957712 POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBM12B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69398 GSE174586_0_v_1_slc4a11_mouse RummaGEO Gene Perturbation Signatures -1.0 null MOLM14 DepMap CRISPR Gene Dependency 1.0 4.19102 NCIH1105 CCLE Cell Line Gene CNV Profiles 1.0 1.65398 PRR13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66205 hsa-miR-4740-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 TRIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17568 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85109 GSE82032_3_v_1_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null PPP1R3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96708 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 MKNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0734 TAL1 ENCODE Transcription Factor Targets 1.0 null H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CCDC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11966 496100625_FWM_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1522 telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056466 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMARCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82676 SEC16A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97598 TNFAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92997 MYCL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95495 DCXR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48923 primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.970374 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.36694 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4309 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null hsa-miR-516b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP1-21924763-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-TMMY-1326-SM-4DXU9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.941806 GSE137914_4_v_1_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54425 GTEX-SNOS-0826-SM-4DM5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.06772 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EEF1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72936 superficial stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.5754 GTEX-QMRM-1126-SM-447BN GTEx Tissue Sample Gene Expression Profiles 1.0 1.04463 Perturb_17530_KO_TET1_SRP150212 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.05712 H3K27me3_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.994 anion binding GO Molecular Function Annotations 2015 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ALDH16A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82215 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06708 MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3076 HSPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48875 JcP contribution to LTL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27275 hsa-miR-513a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Cornu ammonis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.72 DMS79 CCLE Cell Line Gene CNV Profiles -1.0 -1.49216 t61-colon_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.35694 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.04663 CCZ1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68438 hsa-miR-579 TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SKUT1 DepMap CRISPR Gene Dependency 1.0 3.47473 ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BAG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05562 RMGI CCLE Cell Line Gene Expression Profiles 1.0 1.377 Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205729,GSE205731_2_v_3_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null LAMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59931 GTEX-R55G-0326-SM-48FDM GTEx Tissue Sample Gene Expression Profiles 1.0 1.22165 PHF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69601 GLDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.55469 SGSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88706 SUZ12 ChEA Transcription Factor Targets 1.0 null BANF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75243 Viscus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 RAB34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54239 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.935253 TASK1 DepMap CRISPR Gene Dependency 1.0 6.49197 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null centromedian nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39587 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78194 hsa-miR-4639-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCLC22H DepMap CRISPR Gene Dependency 1.0 2.454 gh1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.835 EFE184 CCLE Cell Line Gene CNV Profiles -1.0 -1.47417 CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVN-1226-SM-48TZ5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3796 Artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 mRNA_MYCN_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null NARF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4741 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H4K20me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE111035,GSE111040_8_v_5_plag1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF862 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.118 Lung squamous cell carcinoma_LUSC_TCGA-56-7823-01B-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nutrition disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.503 EEIG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86131 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.3476 NUDT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79989 hsa-miR-4727-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.436802 MLEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60826 regulation of biological quality GO Biological Process Annotations 2015 1.0 null MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null architecture GeneRIF Biological Term Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acute inflammatory response GO Biological Process Annotations 2025 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null ZMIZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75013 TAL1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF460 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81345 RFX5 ENCODE Transcription Factor Targets 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null Mammary-vascular associated smooth muscle cell Tabula Sapiens Gene-Cell Associations 1.0 -0.0740574 Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7782476-41467_2020_20434_MOESM7_ESM.xlsx-KLF14_string_interactions-node2_KLF14 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877285 PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null CSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41016 basolateral nucleus (basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11386 CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JMJD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43338 r1 part of vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.01093 ARF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60042 NUDT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68763 SLR21 CCLE Cell Line Gene Expression Profiles 1.0 1.81216 Perturb_2484_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE186287_1_v_0_ufm1_human RummaGEO Gene Perturbation Signatures -1.0 null Nucleus ambiguus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28076 GTEX-NPJ8-0011-R9a-SM-2YUN5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.90332 GSE224969,GSE224971_3_v_1_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nucleus y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.154 GSE138050,GSE148257_1_v_2_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null QPCT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41321 synaptic vesicle transport GO Biological Process Annotations 2015 1.0 null cellular component organization GO Biological Process Annotations 2015 1.0 null hsa-miR-1343 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.541605 PMC12358297-41388_2025_3481_MOESM3_ESM.xlsx-S9_ASCL1-regulated_genes-Unnamed_1_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4795-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.136254 FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1229 GTEX-T6MO-0726-SM-4DM58 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15962 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T8EM-1226-SM-4DM5J GTEx Tissue Sample Gene Expression Profiles 1.0 0.867006 GSE137914_2_v_1_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null USF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intestine TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Medullary reticular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0267 TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.477 maturity-onset diabetes of the young DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.761 ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.5471 ADCY6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52906 Intergeniculate leaflet of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83559 FSBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95183 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null BARX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06207 Perturb_15323_KD_PLIN2_SRP380168 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.1346 GSE86507,GSE86509_0_v_8_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZDHHC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96565 KIAA0232 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90482 Perturb_1402_KO_HDAC7_SRP402694 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.30854 SLR23 DepMap CRISPR Gene Dependency 1.0 5.5231 ZKSCAN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52683 Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWOO-2026-SM-48TDE GTEx Tissue Sample Gene Expression Profiles 1.0 0.908138 GABBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50826 regulating GeneRIF Biological Term Annotations 1.0 null GTEX-WWYW-0011-R7A-SM-3NB3H GTEx Tissue Sample Gene Expression Profiles 1.0 0.890813 Neonatal diabetes DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.456 ITGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62082 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-498 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 r10 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20434 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R53T-1226-SM-48FCT GTEx Tissue Sample Gene Expression Profiles 1.0 2.81174 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16156 HMGCL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90213 CAPAN1 CCLE Cell Line Gene CNV Profiles 1.0 2.23574 biological regulation GO Biological Process Annotations 2015 1.0 null ZNF618 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.264 KCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49919 SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MTMR9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29463 anterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.945719 ZNF143 ENCODE Transcription Factor Targets 1.0 null dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29434 cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05884 SUCLG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81079 GSE89057_0_v_1_sox5_human RummaGEO Gene Perturbation Signatures 1.0 null Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.935 Prostate adenocarcinoma_PRAD_TCGA-KC-A7FD-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46395 CNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61209 Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_16671_KO_Zfp36l2_SRP310261 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.9065 intermediate stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26715 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TCF12 ENCODE Transcription Factor Targets 1.0 null MAX_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEP170B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04892 PIGP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36757 GSE225901_2_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-136 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 2.95978 GTEX-XXEK-0826-SM-4BRWG GTEx Tissue Sample Gene Expression Profiles 1.0 1.21767 Prostate adenocarcinoma_PRAD_TCGA-V1-A8MJ-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic islet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.103 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null hsa-miR-522 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 VPS25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90708 GTEX-TKQ1-1226-SM-4GICJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.87227 ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null periventricular stratum of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57801 SLC22A23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67142 FYTTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66816 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5327 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral ventrolateral reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40372 GTEX-XXEK-1726-SM-4BRVB GTEx Tissue Sample Gene Expression Profiles 1.0 2.02756 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.900435 planum polare, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.89655 TCF7L2 ENCODE Transcription Factor Targets 1.0 null SPNS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5917 GTEX-QLQW-0326-SM-447A8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15153 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FU-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ALAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41751 GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 2.07331 GSE188870,GSE188871_0_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null RBPMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8037 NCBP2AS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5464 GTEX-QESD-1526-SM-2S1QT GTEx Tissue Sample Gene Expression Profiles 1.0 1.2344 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20058 SUV39H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78883 MAX_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASRGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01882 POLR2AphosphoS5_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ2-0426-SM-4DXUO GTEx Tissue Sample Gene Expression Profiles 1.0 1.1777 GTEX-U3ZH-0926-SM-4DXU4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.843394 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE228894_3_v_2_rnmt_mouse RummaGEO Gene Perturbation Signatures 1.0 null GATA1 ChEA Transcription Factor Targets 1.0 null RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86803 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VJYA-1226-SM-3GIJ6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.854075 TMEM120A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11062 intermediate stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23164 GSE213650_3_v_2_everolimus_human RummaGEO Drug Perturbation Signatures -1.0 null FLNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40881 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84871 hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.966231 TRIP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76107 GATA1_G1E-ER4_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle membrane fusion GO Biological Process Annotations 2015 1.0 null PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15 Rummagene Transcription Factor Associations 2026 1.0 null USF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3583 GTEX-TMMY-1626-SM-4DXTY GTEx Tissue Sample Gene Expression Profiles 1.0 1.03827 INPP5F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93482 SP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36224 GSE95077_5_v_3_amiloride_human RummaGEO Drug Perturbation Signatures -1.0 null TP63 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5065 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 PTEN_KD_GDS2958_101_human_SKBR-3 MAMMARY ADENOCARCINOMA cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Cortical amygdalar area, posterior part, lateral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08389 CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11864 NCIH2196 CCLE Cell Line Gene CNV Profiles -1.0 -1.46418 UM-UC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10267 GSE131588,GSE131690_1_v_0_setd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null CALM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19596 GTEX-Q2AI-1126-SM-48U19 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01876 NCI-H1048 COSMIC Cell Line Gene Mutation Profiles 1.0 null SKRC31 CCLE Cell Line Gene Expression Profiles -1.0 -1.63857 Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null PRR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44314 RUNX3 ENCODE Transcription Factor Targets 1.0 null GATA2 ChEA Transcription Factor Targets 1.0 null efo21 HPA Cell Line Gene Expression Profiles 1.0 1.35196 DMS153 CCLE Cell Line Gene CNV Profiles -1.0 -1.9158 CDIPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85768 MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null heart_5b HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UPIC-1126-SM-4IHLO GTEx Tissue Sample Gene Expression Profiles 1.0 1.2996 CD40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70579 GSE151494_8_v_3_nrp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.95962 REST_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05183 GSE201239_6_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null LCOR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77563 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.17507 REST_Panc1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49307 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null nucleus of the central acoustic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36561 ZNF396 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75907 D341Med DepMap CRISPR Gene Dependency 1.0 2.41222 organelle fusion GO Biological Process Annotations 2015 1.0 null CCZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74446 HNRNPL_02_96 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.0 Kidney Chromophobe_KICH_TCGA-KN-8437-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.896495 MDAMB453 DepMap CRISPR Gene Dependency 1.0 2.20869 NSUN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60662 ETV5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3164 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STK17B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16897 DPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03948 CTCF_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SBDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86424 GTEX-U8XE-0326-SM-3DB8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.18321 H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_11_AR Rummagene Transcription Factor Associations 2026 1.0 null SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30081 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC29A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38643 intracellular membraneless organelle GO Cellular Component Annotations 2025 1.0 null positive regulation of inflammatory response GO Biological Process Annotations 2025 1.0 null RBPJL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72889 CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GUK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65334 Paragigantocellular reticular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99499 H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48088 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null TMEM248 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23288 PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12872_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.262 regulation of cellular localization GO Biological Process Annotations 2015 1.0 null B3GALNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25098 hsa-miR-302c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE137914_2_v_5_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Photoreceptor distal connecting cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.756 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of cell adhesion GO Biological Process Annotations 2025 1.0 null DSP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6551 hsa-miR-520a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GSE111061_1_v_0_tofacitinib_human RummaGEO Drug Perturbation Signatures -1.0 null PLA2G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94368 GSE193993_1_v_3_sstr2_human RummaGEO Gene Perturbation Signatures -1.0 null BICDL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40513 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null free-living state TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.878 dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.935909 CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE145476_2_v_0_hopx_mouse RummaGEO Gene Perturbation Signatures 1.0 null KCNIP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07312 GRHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9287 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.919981 NCIH1395 CCLE Cell Line Gene Expression Profiles 1.0 2.02441 nucleus GO Cellular Component Annotations 2015 1.0 null H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null prethalamic (p3) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3186 TM31 CCLE Cell Line Gene CNV Profiles 1.0 1.37122 ICAM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83792 GTEX-QDVN-1626-SM-48TZC GTEx Tissue Sample Gene Expression Profiles 1.0 0.846331 TLCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95651 MYC-20876797-MEDULLOBLASTOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null nucleolus GO Cellular Component Annotations 2025 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.14775 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11735 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.62883 ventrolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38747 GTEX-U8XE-0626-SM-3DB8U GTEx Tissue Sample Gene Expression Profiles 1.0 1.72575 TAL1_megakaryocyte_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null intergeniculate leaflet Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10731 type GeneRIF Biological Term Annotations 1.0 null CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null plicamycin_homo sapiens_gpl570_gse25127 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.037 GTEX-VUSG-0926-SM-3GIK6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.8564 mantle zone of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61441 CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CYB561D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98696 TE4 CCLE Cell Line Gene Expression Profiles 1.0 1.72117 Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null brain_3b HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 GSE242083,GSE242098_2_v_5_med1_human RummaGEO Gene Perturbation Signatures 1.0 null striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68361 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus GO Cellular Component Annotations 2025 1.0 null EXD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08678 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-373 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 PSKH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55992 GTEX-SE5C-0326-SM-4BRWX GTEx Tissue Sample Gene Expression Profiles 1.0 1.38674 CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1033 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17319 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.8292 PLPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12236 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21388 GSE157383_3_v_2_abemaciclib_human RummaGEO Drug Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS819T CCLE Cell Line Gene Expression Profiles -1.0 -1.775 GTEX-OHPM-1026-SM-3LK74 GTEx Tissue Sample Gene Expression Profiles 1.0 0.892239 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.71381 HCC1897 CCLE Cell Line Gene CNV Profiles -1.0 -1.72301 Perturb_13907_KD_UBE3A_SRP124518 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GSE112962,GSE112963_2_v_1_ddx5_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34987 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3446 LYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29617 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null ARHGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22357 U937 CCLE Cell Line Gene CNV Profiles 1.0 1.63474 caudal linear (raphe) nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26786 CLDN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27842 SMAD3 ChEA Transcription Factor Targets 1.0 null POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU869 DepMap CRISPR Gene Dependency 1.0 4.7914 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PX-01A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE86507,GSE86509_3_v_10_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.094 TADA2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40553 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE149943_2_v_3_cd8a_mouse RummaGEO Gene Perturbation Signatures -1.0 null pancreatic beta cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.55408 TMEM97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.002 FEZF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91097 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null GSE105170,GSE105175_1_v_0_dhx36_human RummaGEO Gene Perturbation Signatures -1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37973 GSE206502_2_v_1_igf2bp1_human RummaGEO Gene Perturbation Signatures 1.0 null striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.987204 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980526 GSE149903_0_v_1_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XXEK-0626-SM-4BRWE GTEx Tissue Sample Gene Expression Profiles 1.0 0.839471 POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.943188 mantle zone of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38806 superficial stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04839 blood GTEx Tissue Gene Expression Profiles -1.0 -1.48109 r7 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46004 Choreaacanthocytosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.343 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nasal lavage fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.742 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4591 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HNF4G_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55759 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.929663 MYC ChEA Transcription Factor Targets 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NCCRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95105 CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.917411 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MTIF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28026 Perturb_14681_KD_NKX22_SRP072566 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.06685 Lipid metabolism disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.009 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.11569 GALT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62708 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4h-LAS1L_KD_upreg_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE149943_2_v_0_cd8a_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-SNMC-0626-SM-4DM6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.0417 intermediate stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4596 KDM4A ENCODE Transcription Factor Targets 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26242 ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.831611 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTSC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61897 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC10592455-NIHMS1912792-supplement-4.xlsx-AHR_encode_CH22_overlap_2021101-ProbeID_AHR Rummagene Transcription Factor Associations 2026 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RO60 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66146 GSE121824,GSE121826_0_v_3_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null SLC6A15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44948 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3727 SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34987 r3 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99308 CISD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93094 Taenia tecta, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92639 CCDC127 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0715 POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null type 2 diabetes GAD Gene-Disease Associations 1.0 null CYTH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97257 REST_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-302e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18257 GTEX-S4Q7-0426-SM-3K2BJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.863768 POU2AF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11033 CHST7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98877 CYB5R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42631 GTEX-WI4N-1126-SM-3LK7Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.25815 OELE CCLE Cell Line Gene Expression Profiles -1.0 -2.38314 RPRD1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72365 lymphnode_4a HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 ALEXANDERCELLS CCLE Cell Line Gene CNV Profiles 1.0 1.45747 GTEX-S33H-1226-SM-4AD69 GTEx Tissue Sample Gene Expression Profiles 1.0 1.65324 GTEX-POMQ-0826-SM-3P61H GTEx Tissue Sample Gene Expression Profiles 1.0 0.893141 GTEX-UPJH-0926-SM-4IHKA GTEx Tissue Sample Gene Expression Profiles 1.0 1.15634 intermediate stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.01093 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.76675 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.23917 HEXD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26687 ATP5MF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26872 ADPRH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63399 PDE12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98161 CHD2 ENCODE Transcription Factor Targets 1.0 null HA-E2F1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal part of m1A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28547 POLR2A ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162892_4_v_0_isox_human RummaGEO Drug Perturbation Signatures 1.0 null SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.36967 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null CTCF_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE224969,GSE224971_3_v_7_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE193993_5_v_7_sstr2_human RummaGEO Gene Perturbation Signatures 1.0 null posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20851 positive regulation of acute inflammatory response GO Biological Process Annotations 2025 1.0 null DUS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52379 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pancreas_6a HPA Tissue Sample Gene Expression Profiles 1.0 1.32661 Congenital limbs-face contractures-hypotonia-developmental delay syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.543 PMC10318747-12864_2023_9472_MOESM2_ESM.xlsx-OCI-AML3_3h_vs_Control-Unnamed_1_RUNX2 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5019 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AJ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95364 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Dentate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84206 rhythmic GeneRIF Biological Term Annotations 1.0 null Gastrointestinal tract TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE254848_4_v_3_ptges_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF566 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4686 GSC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00409 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.950261 ventrolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25563 Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38292 CTCF_WI38_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03024 CTCF_foreskin fibroblast_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-8353-01A-21R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null STARD3NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96181 HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Proinsulin levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.93979 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59625 CTCF_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleus ambiguus, dorsal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27714 Medial temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.588 SIN3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3280_KD_RORC_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-520d-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16761 digestive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072302 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01075 EPCAM_OE_GDS4887_343_human_IL-28B GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22692 GTEX-WWYW-0011-R8A-SM-3NB3S GTEx Tissue Sample Gene Expression Profiles 1.0 1.01856 hsa-miR-34a TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 CTCFL_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H2AC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07012 VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870616 TCF7L2_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MIEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89397 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PIK3R4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99065 GTEX-OHPM-0526-SM-2YUMJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.984535 CTCF_fibroblast of villous mesenchyme_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pancreas HPA Tissue Gene Expression Profiles 1.0 0.855212 exocytosis GO Biological Process Annotations 2015 1.0 null UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null endocrine pancreas TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.481648 GSE181517_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XUZC-0726-SM-4BOPH GTEx Tissue Sample Gene Expression Profiles 1.0 1.33207 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U8XE-1526-SM-4E3HT GTEx Tissue Sample Gene Expression Profiles 1.0 1.78072 PMC9692021-Table_4.xlsx-Table_S4-Table_S4_405_DEGs_of_RA_synovial_tissues_between_NFIL3-high_and_NFIL3-low_group_NFIL3 Rummagene Transcription Factor Associations 2026 1.0 null M07E DepMap CRISPR Gene Dependency 1.0 2.61392 Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0753 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Apolipoprotein B levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 CLOCK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.61 GTEX-V955-0326-SM-4JBGV GTEx Tissue Sample Gene Expression Profiles 1.0 1.09448 hsa-miR-568 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 CFAP126 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90657 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.858946 EZH2 ENCODE Transcription Factor Targets 1.0 null amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2518 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055778 H3K36me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CYB561D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99363 increased mean platelet volume MGI Mouse Phenotype Associations 2023 1.0 null HTR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9434 PLPPR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02208 ACTR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32837 SGF29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3686 CTBP2 ENCODE Transcription Factor Targets 1.0 null CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FLOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.29663 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GCIY CCLE Cell Line Gene Expression Profiles 1.0 1.43296 POLR2A_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66156 PIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75782 LAPTM4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57302 GSE225901_0_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null TBX20-22328084-HEART-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4888-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WOFL-0826-SM-3MJG1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.947476 C8orf33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53003 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.856003 POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SELENOK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71166 Lung squamous cell carcinoma_LUSC_TCGA-58-8391-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null CTCF_cardiac muscle cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11933697-41467_2025_58216_MOESM9_ESM.xlsx-SD7_C_R_NS1_Med_ATF3_DEG-symbol_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-1208 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 GSE244072_10_v_1_tfeb_mouse RummaGEO Gene Perturbation Signatures 1.0 null ERF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3683 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null sodium GeneRIF Biological Term Annotations 1.0 null GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles 1.0 1.02137 GTEX-RM2N-1126-SM-48FCY GTEx Tissue Sample Gene Expression Profiles 1.0 0.86016 hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24828 ZNF282 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64137 fusiform gyrus, left, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.833867 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979515 CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42736 NCIH2029 CCLE Cell Line Gene CNV Profiles -1.0 -1.34678 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VK-01A-21R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRA_RXRA Rummagene Transcription Factor Associations 2026 1.0 null Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81674 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM10248_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_astrocyte of the cerebellum_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05505 GATA1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BHLHE40_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SERTAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28462 GTEX-TML8-0526-SM-32QOQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.07756 GSE174701_1_v_0_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null SLR24 CCLE Cell Line Gene Expression Profiles -1.0 -2.17593 MAX ENCODE Transcription Factor Targets 1.0 null CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U8XE-0926-SM-3DB8V GTEx Tissue Sample Gene Expression Profiles 1.0 1.07184 COA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98465 CTCF_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null TR146 DepMap CRISPR Gene Dependency 1.0 2.58606 CEBPB ENCODE Transcription Factor Targets 1.0 null GSE224969,GSE224971_0_v_1_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PHC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94116 RNF145 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38637 UBXN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17196 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PLEKHF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87806 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QV31-0626-SM-447C5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.939572 Piriform-amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.42756 RAB38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8608 222 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.118 JHOS2 CCLE Cell Line Gene CNV Profiles -1.0 -1.74916 Dendritic branch point COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.543 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46313 MYC_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YV-1126-SM-3LK73 GTEx Tissue Sample Gene Expression Profiles 1.0 0.843482 ZNF717 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52355 MTMR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89212 Paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28031 SMARCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35456 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 hsa-miR-3662 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 MRPL39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3057 GTEX-VJYA-1026-SM-4KL21 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19487 Prostate adenocarcinoma_PRAD_TCGA-VN-A88P-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE150895,GSE150896_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null striohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2281 GTEX-NPJ8-2226-SM-3TW8D GTEx Tissue Sample Gene Expression Profiles 1.0 1.78008 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UPK5-2026-SM-4JBIM GTEx Tissue Sample Gene Expression Profiles 1.0 0.846096 GTEX-QLQW-0226-SM-447BJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.63987 MIN-6 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.934 MUTZ8 DepMap CRISPR Gene Dependency 1.0 3.28231 CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null colonrectum_a HPA Tissue Sample Gene Expression Profiles 1.0 1.64525 TTYH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64705 GSE133763_0_v_2_chd1_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20473 SNU119 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 CNFN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04028 USP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85239 secretion by cell GO Biological Process Annotations 2015 1.0 null Primary somatosensory area, barrel field, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43229 cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.05278 SNU520 CCLE Cell Line Gene Expression Profiles 1.0 1.45138 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.925547 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.2372 chr15_61911685_T_A_b38 GTEx eQTL 2025 1.0 1.55724 GTEX-X261-0011-R8A-SM-4E3I5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02902 Pancreas TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.947 CTCF_fibroblast of lung_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3771 GTEX-PWOO-1226-SM-48TCO GTEx Tissue Sample Gene Expression Profiles 1.0 1.85706 USF1 ENCODE Transcription Factor Targets 1.0 null RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleolus GO Cellular Component Annotations 2023 1.0 null FDX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51647 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.001 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17929 H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NFYB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86468 CKLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32368 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855019 CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-0926-SM-48TD7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40637 USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.862802 PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR Rummagene Transcription Factor Associations 2026 1.0 null cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.975395 TAL1_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F6 ENCODE Transcription Factor Targets 1.0 null SH2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28533 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6715 NFIC_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MICOS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90259 ZNF26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57019 USF MotifMap Predicted Transcription Factor Targets 1.0 null GSE136869_1_v_0_lpar2_mouse RummaGEO Gene Perturbation Signatures -1.0 null LAMA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25895 Nucleolus COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Type 2 diabetes GWAS Catalog SNP-Phenotype Associations 2025 1.0 3.21549 SIK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52137 SAMD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48154 SIN3A ENCODE Transcription Factor Targets 1.0 null COPRS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26226 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ethanol_mus musculus_gpl6105_gds3703 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GNAZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50973 disease of metabolism DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.835734 Medial group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11602 GTEX-VJYA-0826-SM-4KL1M GTEx Tissue Sample Gene Expression Profiles 1.0 1.10724 regulation of vascular permeability involved in acute inflammatory response GO Biological Process Annotations 2023 1.0 null parvicellular part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36561 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.7452 MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.0709 MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null heart_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 PHOX2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24729 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GTEX-X261-0011-R10B-SM-4E3JT GTEx Tissue Sample Gene Expression Profiles 1.0 1.04753 PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6 Rummagene Transcription Factor Associations 2026 1.0 null PMC8596853-41586_2021_4103_MOESM4_ESM.xlsx-ST18-Unnamed_5_ST18 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.59579 GSE133764_2_v_0_chd2_human RummaGEO Gene Perturbation Signatures 1.0 null HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.850279 MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEUROD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1091 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NAMALWA DepMap CRISPR Gene Dependency 1.0 2.16621 TERF2IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61352 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NAGS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80091 GTEX-S4Q7-1526-SM-3K2AG GTEx Tissue Sample Gene Expression Profiles 1.0 1.16734 APOBEC3F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12656 Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11074 GNAI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21415 alimentary canal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null outer CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00374 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null single GeneRIF Biological Term Annotations 1.0 null LOVO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07096 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SYT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49344 UVSSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36155 leak GeneRIF Biological Term Annotations 1.0 null NAA16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73448 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21211 CTCF_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null GSE159148_0_v_1_sdc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null SEC14L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19325 Ventral posteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07139 TEAD4 ENCODE Transcription Factor Targets 1.0 null outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30194 H3K36me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEX3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67507 GSE121824,GSE121826_0_v_7_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31887 H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1072 CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRKAR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20408 regulation of transport GO Biological Process Annotations 2015 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null PCI6A DepMap CRISPR Gene Dependency 1.0 2.18118 GTEX-QLQW-0726-SM-447AA GTEx Tissue Sample Gene Expression Profiles 1.0 0.900723 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.959284 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.83593 RHEBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35035 GSE148692,GSE148695_5_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC11648256-mmc3.xlsx-Tab_S2_AA_Mod_27_SNP_BMI_INT-Unnamed_1_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06101 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null U118MG CCLE Cell Line Gene Expression Profiles -1.0 -1.75525 H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.83117 RERFLCKJ CCLE Cell Line Gene Expression Profiles 1.0 1.48539 CoPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48525 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M9-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null clathrin binding GO Molecular Function Annotations 2015 1.0 null H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.68 TRIM28 ENCODE Transcription Factor Targets 1.0 null ARHGEF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59209 MFSD13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10154 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09233 outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5314 MAX_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052847 inner SZ in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.849706 ATF2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterus-epithelial cell of uterus Tabula Sapiens Gene-Cell Associations 1.0 0.767954 Perturb_2492_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE207514,GSE207515_2_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures -1.0 null CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2354 CAPN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53962 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TOMM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46643 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null inferior occipital gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.863183 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.895901 pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.318272 NID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80597 GTEX-R53T-0426-SM-48FEM GTEx Tissue Sample Gene Expression Profiles 1.0 1.74659 single-organism membrane organization GO Biological Process Annotations 2015 1.0 null nuclear part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044748 POLR2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDYL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05073 PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NL4W-0011-R2a-SM-2I5GV GTEx Tissue Sample Gene Expression Profiles 1.0 0.923299 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.389 intracellular organelle GO Cellular Component Annotations 2015 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH2004RT DepMap CRISPR Gene Dependency 1.0 3.28655 MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PECAPJ34CLONEC12 CCLE Cell Line Gene CNV Profiles 1.0 1.44211 GSE174701_5_v_8_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TRIM68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10868 primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0779 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 C1QL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17539 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OTUD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20393 REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NMCG1 CCLE Cell Line Gene Expression Profiles -1.0 -1.94004 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.92711 GTEX-PWOO-0826-SM-48TCL GTEx Tissue Sample Gene Expression Profiles 1.0 1.18294 GSE145476_2_v_3_hopx_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PDRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92321 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00876 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04305 NCIH2122 CCLE Cell Line Gene CNV Profiles 1.0 1.59749 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null vesicle organization GO Biological Process Annotations 2015 1.0 null H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null BAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27732 SLC25A22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72227 anterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.859047 gastrointestinal tract TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CNOT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64595 REST_Panc1_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null OARD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53019 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-0926-SM-2HMIZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.31505 GTEX-QXCU-1926-SM-48FE4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.06672 H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null TBRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5025 CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4781-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 RBBP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65949 TAF6L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.286 TTC709 DepMap CRISPR Gene Dependency 1.0 4.0705 GTEX-WHSE-0126-SM-3NMBT GTEx Tissue Sample Gene Expression Profiles 1.0 1.34422 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.898993 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.878244 developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.076983 Alimentary canal TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 maturity-onset diabetes of the young type 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.259 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-20a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTBP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of vesicle-mediated transport GO Biological Process Annotations 2015 1.0 null ESRRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.41459 Lung adenocarcinoma_LUAD_TCGA-05-4418-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LN443 CCLE Cell Line Gene Expression Profiles -1.0 -1.5236 REST_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3561 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.6783 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32432 GSE109565_12_v_11_glyphosate_human RummaGEO Drug Perturbation Signatures -1.0 null HMGB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80898 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8362 NCIH292 CCLE Cell Line Gene Expression Profiles -1.0 -3.02889 MAZ ENCODE Transcription Factor Targets 1.0 null SUZ12-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ZNF570 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58983 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null NG-108-15 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.949 KON COSMIC Cell Line Gene Mutation Profiles 1.0 null DCAF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31399 RUNX1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.935081 TMC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2984 Lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.825031 GATA2 ENCODE Transcription Factor Targets 1.0 null FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.7644 RBMX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40668 ADPRM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68432 SK-MES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null reticulum GeneRIF Biological Term Annotations 1.0 null PDCD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00549 GSE128076_1_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XUJ4-1226-SM-4BOPD GTEx Tissue Sample Gene Expression Profiles 1.0 1.0547 CORL279 CCLE Cell Line Gene CNV Profiles -1.0 -1.47828 C18orf25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91657 DCAKD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12397 Perturb_3533_OE_HLAG_SRP386253 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null QSER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70651 RELA_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null voltage-gated potassium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.785 GSE224969,GSE224971_0_v_5_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null KMH2 CCLE Cell Line Gene CNV Profiles 1.0 1.67829 ANXA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54522 C16orf86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00585 hsa-miR-4799-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Colorectum TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NCOA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46834 Dorsal column nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26959 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.786 phospholipid binding GO Molecular Function Annotations 2015 1.0 null BLTP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32467 hsa-miR-4257 TargetScan Predicted Conserved microRNA Targets 1.0 0.265648 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.903377 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE213632_1_v_5_acod1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38548 ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.3933 CREB1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-PSDG-1026-SM-48TCV GTEx Tissue Sample Gene Expression Profiles 1.0 1.15157 GSPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22108 nucleus of the inferior collicular brachium, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52295 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KIAA1549 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35893 GAS2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91852 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IJ-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RUNX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29435 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14669_KO_Prkaa1/Prkaa2_ERP006813 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.4706 Rectum adenocarcinoma_READ_TCGA-DC-6681-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14811 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.828712 Adrenocortical carcinoma_ACC_TCGA-OR-A5LP-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNASE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95184 PPARG-20176806-3T3-L1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null REST_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null control GeneRIF Biological Term Annotations 1.0 null GSE107854_2_v_0_prmt5_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE230573_1_v_0_dcaf1_human RummaGEO Gene Perturbation Signatures 1.0 null Prediabetes syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.383 intermediate part of the arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11389 HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FMNL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91399 BBLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85485 GSE137914_4_v_5_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null B3GALT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22986 LN382 DepMap CRISPR Gene Dependency 1.0 2.03758 GSE128634,GSE128636_4_v_5_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_3900_KO_TCF7L2_SRP314475 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.87731 GSE186287_2_v_0_ufm1_human RummaGEO Gene Perturbation Signatures 1.0 null HOXA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59491 mantle zone of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54137 MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-1026-SM-4DM4Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.5135 CHLA90 DepMap CRISPR Gene Dependency 1.0 4.58575 CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZFP62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46573 EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null COL9A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44012 hsa-miR-449a TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 hsa-miR-3173-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 mantle zone of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02559 LRWD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58624 colon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18503 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.988 PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG Rummagene Transcription Factor Associations 2026 1.0 null orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.93953 SMARCB1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OTUD6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96463 GATA1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-1126-SM-48FDZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.878581 POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980526 ZNF726 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86165 GPR25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34926 PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-geneid_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null HNF4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92223 H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PRC1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.37 protein binding GO Molecular Function Annotations 2015 1.0 null temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00024 CTCFL_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CNBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10236 ZNRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50761 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16737 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32594 GARIN5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33132 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13403 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42421 POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic alpha cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.363 KMS26 CCLE Cell Line Gene Expression Profiles -1.0 -1.55704 RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventral posterior medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41609 YIPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6571 PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null layer 1 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33335 GTEX-SIU7-1626-SM-4BRUK GTEx Tissue Sample Gene Expression Profiles 1.0 0.901639 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22992 CDK8_knockdown_147_GSE32108 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.59991 layer 3 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51071 H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12865_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM171B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38803 HINT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80654 RBBP5 ENCODE Transcription Factor Targets 1.0 null BTG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80699 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE128634,GSE128636_1_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15227 GATA2-19941826-K562-human ChEA Transcription Factor Binding Site Profiles 1.0 null HELT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53669 supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32908 STAT3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2009 DepMap CRISPR Gene Dependency 1.0 3.14693 Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61H-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.59942 TRAFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57853 PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_upreg_AR Rummagene Transcription Factor Associations 2026 1.0 null SERPINE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49886 UBB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58903 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02605 Taenia tecta, ventral part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89638 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46617 CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-1126-SM-48TZM GTEx Tissue Sample Gene Expression Profiles 1.0 1.06772 ZFPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51232 r8 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07284 HERC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32743 H3K27me3_CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CLOCK-BMAL transcription complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.628 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.926653 CLPTM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30391 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24678 A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.25446 hsa-miR-27b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 P2RX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7402 Paragigantocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78069 CTCF_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10624 ELK4 JASPAR Predicted Transcription Factor Targets 1.0 null GSE72895,GSE72896_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC10592455-NIHMS1912792-supplement-4.xlsx-AHR_encode_CH22_overlap_2021101-hgnc_symbol_AHR Rummagene Transcription Factor Associations 2026 1.0 null ZNF773 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29087 hsa-miR-222 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 KURAMOCHI CCLE Cell Line Gene Expression Profiles -1.0 -2.26234 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1437 CCLE Cell Line Gene CNV Profiles 1.0 1.37745 TCAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45263 MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OSBPL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24545 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13455 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3 Rummagene Transcription Factor Associations 2026 1.0 null anteroventral part of alar thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53338 large intestine TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_5830_KO_Ddx41_SRP325771 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.6739 GSE57871_11_v_10_vorinostat_human RummaGEO Drug Perturbation Signatures 1.0 null orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.21622 GTEX-WFON-0626-SM-4LVLX GTEx Tissue Sample Gene Expression Profiles 1.0 1.75511 GTEX-U8XE-0826-SM-4E3J1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.9765 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SMZ1 DepMap CRISPR Gene Dependency 1.0 3.98386 parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03887 IKBIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96488 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.6758 liver GTEx Tissue Gene Expression Profiles 1.0 0.900688 ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8968 intracellular non-membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNF185 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85169 CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEC6 CCLE Cell Line Gene Expression Profiles -1.0 -1.5592 HK2 CCLE Cell Line Gene Expression Profiles -1.0 -1.82908 GTEX-PWN1-1526-SM-48TDA GTEx Tissue Sample Gene Expression Profiles 1.0 1.25731 TRIL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92216 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28118 Hyperglycemia HuGE Navigator Gene-Phenotype Associations 1.0 null RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATG101 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39016 ACO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00725 Perturb_5833_KO_Hnrnpl_SRP042164 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.21298 BMI1-23680149-NPCS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RRP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58443 BLTP3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45881 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.827392 HDAC2_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR1I2-20693526-LIVER-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null mRNA_MYC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null MPI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32755 Lung squamous cell carcinoma_LUSC_TCGA-66-2773-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE128634,GSE128636_2_v_5_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-499a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null FBXW4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43182 RNASEH2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37473 PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIOBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37965 TLNRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28686 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_14364_KD_SCD_SRP352005 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.9378 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null endometrium HPA Tissue Gene Expression Profiles 1.0 0.849557 TMEM223 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58894 PMC11747033-Table1.xlsx-Sup_Table_S1-IFNy_LPS_TREATED_HMEC_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4707 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.92331 GSE210885_2_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null GTEX-V1D1-1726-SM-4JBHB GTEx Tissue Sample Gene Expression Profiles 1.0 0.936267 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.106 PSMG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3253 anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.889585 GTF2E2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58853 ATF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9631 FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.0236 ZNF770 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52011 Perturb_15115_KD_Rtn4_SRP278924 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.17799 GTEX-WHSE-0011-R1A-SM-3P5ZK GTEx Tissue Sample Gene Expression Profiles 1.0 1.35699 TTK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58584 GSE136397_1_v_0_dextran_mouse RummaGEO Drug Perturbation Signatures -1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68909 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE128076_2_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null ETS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7673 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE174406_2_v_0_lin28b_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null spleen GTEx Tissue Gene Expression Profiles -1.0 -1.02954 PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null TP53I11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14801 cellular GeneRIF Biological Term Annotations 1.0 null TCF7L2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU1272 CCLE Cell Line Gene CNV Profiles -1.0 -1.85786 Height GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.2699 r9 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07806 GTEX-U4B1-0726-SM-4DXUA GTEx Tissue Sample Gene Expression Profiles 1.0 1.24137 RSC1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86179 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.895899 H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE133763_0_v_1_chd1_human RummaGEO Gene Perturbation Signatures 1.0 null MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO775 CCLE Cell Line Gene CNV Profiles 1.0 1.35773 PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6 Rummagene Transcription Factor Associations 2026 1.0 null COX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25957 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE151494_1_v_4_nrp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SMCHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95653 regulation of exocytosis GO Biological Process Annotations 2015 1.0 null RUNX1 ChEA Transcription Factor Targets 1.0 null internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31862 PC-3M cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.347 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.009 dorsolateral part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36561 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8175-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61152 Perturb_8500_OE_RAS_SRP150620 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.5317 H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2481_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SNU739 DepMap CRISPR Gene Dependency 1.0 2.27758 Fasting blood proinsulin levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.71549 NPAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45693 TSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02604 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Z-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C3orf80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11113 EDEM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94088 Stomach Smooth Muscle Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.36892 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00098 Nucleus of Darkschewitsch Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51071 CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40886 GTEX-S3XE-0526-SM-4AD4G GTEx Tissue Sample Gene Expression Profiles 1.0 0.899183 GSE158969_1_v_0_trastuzumab_human RummaGEO Drug Perturbation Signatures -1.0 null USF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9753 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38227 lateral part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38548 hsa-miR-548a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Perturb_4868_KO_NEUROG3_ERP110708 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.9208 CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE174383_4_v_7_ly6d_mouse RummaGEO Gene Perturbation Signatures 1.0 null RELA ENCODE Transcription Factor Targets 1.0 null GSE225901_0_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null REST_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRO-1926-SM-2S1O3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05083 ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3198 GSE188382_2_v_0_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96779 CDIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89769 CHST14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81996 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE181959_1_v_2_dextran_mouse RummaGEO Drug Perturbation Signatures -1.0 null SHD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22173 TPRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42388 GTEX-WZTO-0426-SM-3NM99 GTEx Tissue Sample Gene Expression Profiles 1.0 0.840109 RPL7L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95228 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10075 r3 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16978 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 2.40495 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02247 H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-93 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 BACE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45814 GLCCI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58724 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4724 AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4769-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.404082 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.1728 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null navicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14938 RB1_KD_GSE50532_593_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_15010_KO_Eed_SRP365240 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.94169 GSE228894_0_v_1_rnmt_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.845633 16474848-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null UMUC3 CCLE Cell Line Gene CNV Profiles 1.0 1.3309 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U8XE-0526-SM-3DB8R GTEx Tissue Sample Gene Expression Profiles 1.0 1.27081 E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null r9 part of external cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57945 periventricular stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.03983 LCMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57526 nuclear body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.270068 type 2 diabetes mellitus DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 1.35663 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18872 CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE148262,GSE150691_3_v_2_hdlbp_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5034-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE149769_1_v_0_nlrp12_mouse RummaGEO Gene Perturbation Signatures -1.0 null HT1197 CCLE Cell Line Gene CNV Profiles -1.0 -1.5822 BHLHA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53005 GSE158834_2_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null GSE135514_8_v_7_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null Basolateral amygdalar nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73983 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null smoothmuscle_8a HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 GSE137914_0_v_5_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USP2_KO_GSE43517_20_mouse_kidney GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 HOXC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1613 HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.592 HCC1419 CCLE Cell Line Gene Expression Profiles 1.0 1.44551 GSE128634,GSE128636_4_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42405 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.960143 dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18632 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12867_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07344 Longissimus lumborum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.515 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63319 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inner CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.853533 LITAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78608 ZSCAN20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65085 colonrectum_d HPA Tissue Sample Gene Expression Profiles 1.0 0.861839 CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RFXAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51162 CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null UBTF ENCODE Transcription Factor Targets 1.0 null TCF7L2_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE238116_3_v_2_egr1_human RummaGEO Gene Perturbation Signatures -1.0 null SU-DHL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18257 cell part LOCATE Predicted Protein Localization Annotations 1.0 null AP1S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20651 UACC893 CCLE Cell Line Gene Expression Profiles 1.0 1.62738 E2F6_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null diabetes mellitus DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 1.35663 H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GABPA_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NM-01A-21R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RSRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24679 PTF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55654 carbohydrate metabolism disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 1.35663 GATA1_G1E-ER4_mm9_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2 Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Large intestine TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Neuron projection branch point COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.543 GTEX-QCQG-0526-SM-48U2A GTEx Tissue Sample Gene Expression Profiles 1.0 0.837052 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE60837_2_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-U8XE-1426-SM-3DB8Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.15349 GTEX-NPJ8-2126-SM-3MJGK GTEx Tissue Sample Gene Expression Profiles 1.0 1.35267 SLC39A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40268 REST_Panc1_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.94303 hsa-miR-3613-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 MACF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53115 AGPAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.371 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3177 GADD45GIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35177 KLHL17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57104 calcium-dependent phospholipid binding GO Molecular Function Annotations 2015 1.0 null pancreatic islet TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.490229 GTEX-S32W-1926-SM-4AD63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05039 EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U8XE-0226-SM-4E3J3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3531 GSE233049_1_v_0_atf3_human RummaGEO Gene Perturbation Signatures 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31272 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.31502 BRI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44594 PLCB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67041 single-organism membrane fusion GO Biological Process Annotations 2015 1.0 null ZNF816 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22715 GTEX-XMK1-1726-SM-4B64Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.944422 EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPL-1026-SM-3MJGI GTEx Tissue Sample Gene Expression Profiles 1.0 1.08903 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13403 GSE107505_1_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null USF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMGN3 ENCODE Transcription Factor Targets 1.0 null FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.181 GSE151494_10_v_3_nrp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TBX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1418 KDELR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53265 H4K20me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BEND5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60247 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27071 Fasting glucose GWAS Catalog SNP-Phenotype Associations 2025 1.0 3.55229 ZNF367 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55612 GTEX-V1D1-0726-SM-4JBH7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25556 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.3271 GSE211262,GSE211263_2_v_1_pbrm1_human RummaGEO Gene Perturbation Signatures 1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AH-6644-01A-21R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8054-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF324B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38162 KLF16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56818 CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12868_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17680_KO_Foxo1_SRP063560 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.607323 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.73906 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE234289_4_v_2_rfx6_human RummaGEO Gene Perturbation Signatures -1.0 null binding GO Molecular Function Annotations 2015 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null ILKAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74303 intermediate stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27778 VMRCLCD CCLE Cell Line Gene CNV Profiles 1.0 1.73797 OCUM1 CCLE Cell Line Gene CNV Profiles 1.0 1.84064 GTEX-XGQ4-1326-SM-4GIDU GTEx Tissue Sample Gene Expression Profiles 1.0 0.961258 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null PRKAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53014 supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.868826 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.77424 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5625-01A-01R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912156 ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.824066 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null hsa-miR-34c-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 superior rostral gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.864711 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21-21589869-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6801 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_2_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null anterior pretectal nucleus, ventral core part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23127 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.829541 Lung squamous cell carcinoma_LUSC_TCGA-58-A46J-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GPX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21014 GTEX-S32W-0326-SM-2XCBI GTEx Tissue Sample Gene Expression Profiles 1.0 0.867636 cation binding GO Molecular Function Annotations 2015 1.0 null 253JBV CCLE Cell Line Gene Expression Profiles 1.0 1.61674 r5 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11389 ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.8037 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22782 H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31353 GTEX-WHSE-0011-R3A-SM-3P5ZM GTEx Tissue Sample Gene Expression Profiles 1.0 0.873158 CCDC74B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72895 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ENDOV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.33253 GTEX-OXRK-1626-SM-3NB17 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10422 MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.948089 CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WHSE-0926-SM-3NMBS GTEx Tissue Sample Gene Expression Profiles 1.0 1.62389 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40614 MRPL43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06962 PTPRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8012 r8 portion of ambiguous motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03059 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ion binding GO Molecular Function Annotations 2015 1.0 null FOXP1-21924763-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04473 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7156 NUP43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5868 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.903377 Rectum adenocarcinoma_READ_TCGA-EI-6882-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null SCMCRM2 DepMap CRISPR Gene Dependency 1.0 2.81604 FZD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87516 H4K20me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null calcium ion binding GO Molecular Function Annotations 2015 1.0 null F8A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9238 RELA-24523406-FIBROSARCOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Overnutrition DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.507 Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09779 SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1 ENCODE Transcription Factor Targets 1.0 null ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29949 TSPAN33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03293 GTEX-WHSE-0011-R2A-SM-3P5ZL GTEx Tissue Sample Gene Expression Profiles 1.0 0.910726 ZBTB7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06517 REST ENCODE Transcription Factor Targets 1.0 null GATA1_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.814 vacuole-mitochondrion membrane contact site COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.657 MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZDHHC22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65323 GTEX-SIU7-0926-SM-4BRX1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05294 Neuroacanthocytosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.266 CAPAN2 CCLE Cell Line Gene CNV Profiles 1.0 2.77067 GTEX-PX3G-1626-SM-2S1PT GTEx Tissue Sample Gene Expression Profiles 1.0 0.961626 MMP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17802 ABHD17B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77244 ABTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98082 MAP3K11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94336 496100389_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.11465 DHX38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31003 rectum_8c HPA Tissue Sample Gene Expression Profiles 1.0 1.00345 MYC_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GET3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76524 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9337 organelle LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-20b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC2A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3858 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.55713 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22514 MAGED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.50345 Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hatching gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.622 ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARHGAP27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58979 MRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15532 Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C2 domain InterPro Predicted Protein Domain Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFCP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5102 REST_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2193 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VG-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC17A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10644 CTCF_GM12869_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TM7SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88507 GSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3182 H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE121824,GSE121826_0_v_2_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null BJHTERT CCLE Cell Line Gene Expression Profiles -1.0 -1.47064 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TRNP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1317 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17628 RAD21 ChEA Transcription Factor Targets 1.0 null Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30372 Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39025 GTEX-S3XE-1326-SM-4AD4H GTEx Tissue Sample Gene Expression Profiles 1.0 1.4217 H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CRMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61004 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18872 Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SKCO1 CCLE Cell Line Gene Expression Profiles 1.0 1.56058 GSE174701_4_v_7_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null Mediodorsal nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04511 AMOTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01355 Obesity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.509 FBXO38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57922 GABPA ENCODE Transcription Factor Targets 1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.917411 REST_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3605 channel GeneRIF Biological Term Annotations 1.0 null ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1768 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ADIPOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44085 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.872999 MAP2K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18392 MLKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83276 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null GSE95685_4_v_5_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.969947 ZNF205 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08363 EBF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34983 Diabetes Mellitus DisGeNET Gene-Disease Associations 1.0 null regulation of cell adhesion GO Biological Process Annotations 2023 1.0 null RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 2.54346 RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.2386 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXD4L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.30813 CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE224969,GSE224971_0_v_7_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RNF208 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76581 H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REST_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ST486 DepMap CRISPR Gene Dependency 1.0 2.16774 superficial stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27778 KIAA1522 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94048 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09475 GSE118794_0_v_4_zmynd8_mouse RummaGEO Gene Perturbation Signatures 1.0 null fatty-acyl-CoA synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.767 Endocrine pancreas TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.101 CCDC74A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67881 Cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32676 H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE137914_2_v_3_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null NFIC ENCODE Transcription Factor Targets 1.0 null GTEX-PW2O-0826-SM-48TC5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09976 regulation of cellular process GO Biological Process Annotations 2015 1.0 null cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18963 POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE236502_2_v_3_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null EXTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34479 Perturb_17541_KD_MEOX1_SRP213607 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85109 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null regulation of vascular permeability involved in acute inflammatory response GO Biological Process Annotations 2025 1.0 null SP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.878574 CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null icSARA deltaORF6_0Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.51294 ELK1::HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1842 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.95597 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S3XE-1826-SM-3K2B4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.905935 MEX3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80532 TBX20-22080862-HEART-MOUSE ChEA Transcription Factor Targets 2022 1.0 null temporotympanic muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09659 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21341 ALYREF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30908 REST_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73494 RCOR1 ENCODE Transcription Factor Targets 1.0 null AFF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46554 hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34343 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2747 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46919 GTEX-T5JC-1526-SM-4DM68 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18556 Postsubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23008 GSE164463_4_v_1_pax6_mouse RummaGEO Gene Perturbation Signatures 1.0 null USP32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69597 DDX42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37235 ZFP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14807 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.903377 subethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88238 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE137914_4_v_3_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null USF1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC25A25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8879 GSE148692,GSE148695_1_v_0_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null RAPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89707 Taenia tecta, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25249 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.73935 PANC0813 DepMap CRISPR Gene Dependency 1.0 2.99044 trastuzumab_homo sapiens_gpl570_gse15043 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE193993_0_v_7_sstr2_human RummaGEO Gene Perturbation Signatures 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null YIPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95901 GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles 1.0 0.972761 DMRTA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57647 MYOG ENCODE Transcription Factor Targets 1.0 null GSE148692,GSE148695_2_v_0_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GAMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58247 ETF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68219 GTEX-Q2AI-0526-SM-2I3EJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.973128 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null smoothmuscle_8b HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 Lung adenocarcinoma_LUAD_TCGA-62-A471-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923995 eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF276 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92773 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05141 GTEX-XXEK-1126-SM-4BRUX GTEx Tissue Sample Gene Expression Profiles 1.0 2.63583 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventral paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.01093 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041512 DYNLT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45842 CTCF_GM12866_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null LRFN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51812 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.51028 Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTHFD1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69258 496100453_HIP_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.7764 m1AD (DM) part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.03983 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09831 SYCP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11375 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVISE CCLE Cell Line Gene Expression Profiles 1.0 1.50369 CDC14C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63896 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.835734 hsa-miR-17 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dendritic lamellar body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.771 hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.87234 GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE192870_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null JM1 DepMap CRISPR Gene Dependency 1.0 2.63426 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null F2R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89496 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00446 GSE199255,GSE199356_3_v_5_pds5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null NPAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47334 Brain Lower Grade Glioma_LGG_TCGA-TM-A84C-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WRNIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02755 ATMIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79261 H3K27me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SP140L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93414 r8 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32716 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2513 regulation of secretion GO Biological Process Annotations 2015 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.917411 REC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.94903 Piriform-amygdalar area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.37595 GOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25211 JAG1_OE_GDS3571_40_human_endometrial stromal cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE244072_4_v_6_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null GJC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49652 ONS76 CCLE Cell Line Gene CNV Profiles -1.0 -1.71818 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Insulinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.86 GTEX-XV7Q-1326-SM-4BRWM GTEx Tissue Sample Gene Expression Profiles 1.0 1.22146 autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.369628 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.53123 GTEX-V1D1-2426-SM-3GAER GTEx Tissue Sample Gene Expression Profiles 1.0 0.919802 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null fasciola cinerea Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02458 rt4 HPA Cell Line Gene Expression Profiles 1.0 0.983647 RBM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43605 Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE224763_1_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE198165,GSE198166_7_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE111035,GSE111040_8_v_12_plag1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNU1214 CCLE Cell Line Gene CNV Profiles 1.0 1.66676 Basolateral amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51071 PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53993 501A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.05149 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.917411 CHRNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8056 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4796-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 layer 1 of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78333 PMC7892341-41388_2020_1606_MOESM3_ESM.xlsx-Tables_S4-RNA-seq_LetR_only_AIB1_differentially_expressed_genes_not_present_in_MCF7_cells_Related_to_Figure_1_NCOA3 Rummagene Transcription Factor Associations 2026 1.0 null ZNF140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.877 CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NANOG ENCODE Transcription Factor Targets 1.0 null PMC7373278-pone.0236187.s013.xlsx-MCF7_genes_overexpressed_in_AR-Gene_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ANXA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05329 superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63774 LPS6 DepMap CRISPR Gene Dependency 1.0 2.65125 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TRO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4896 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.97864 GSE162892_4_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null TP53 ChEA Transcription Factor Targets 1.0 null secretion GO Biological Process Annotations 2015 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.84621 NR3C2-34362910-WISTARRAT-HIPPOCAMPUS ChEA Transcription Factor Targets 2022 1.0 null amygdaloid complex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.881072 CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7429-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25912 H3K27me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null synaptic vesicle exocytosis GO Biological Process Annotations 2015 1.0 null HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.86973 ICC2 DepMap CRISPR Gene Dependency 1.0 3.21172 CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GNG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03775 Diabetes Mellitus, Type 2 CTD Gene-Disease Associations 1.0 2.88009 PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10 Rummagene Transcription Factor Associations 2026 1.0 null MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50817 Perturb_17732_KO_Tmprss2_SRP046010 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.524 Perturb_2483_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 vesicle fusion GO Biological Process Annotations 2015 1.0 null GTEX-WFG8-1626-SM-4LVMB GTEx Tissue Sample Gene Expression Profiles 1.0 1.16773 GTEX-PWOO-0626-SM-48TZH GTEx Tissue Sample Gene Expression Profiles 1.0 1.30014 hsa-miR-4459 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 PMC7782476-41467_2020_20434_MOESM7_ESM.xlsx-KLF14_string_interactions-node1_KLF14 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U8XE-2526-SM-4E3IT GTEx Tissue Sample Gene Expression Profiles 1.0 2.47557 H3K27me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null p3 portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18228 Pancreas TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.616 Geniculate group, ventral thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02181 locomotion GeneRIF Biological Term Annotations 1.0 null ACCMESO1 CCLE Cell Line Gene Expression Profiles -1.0 -1.45456 Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054112 H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null establishment of vesicle localization GO Biological Process Annotations 2015 1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.72908 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP110 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37212 CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Interstitial nucleus of Cajal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1315 ethanol_mus musculus_gds3703 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PNMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95078 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.868166 POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null p1 portion of the paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1285 HNRNPUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00588 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.879882 ALDOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56273 GTEX-S95S-0726-SM-4B64H GTEx Tissue Sample Gene Expression Profiles 1.0 1.5582 TAF1 ENCODE Transcription Factor Targets 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055568 GATA3 ENCODE Transcription Factor Targets 1.0 null Parasolitary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1477 MAX_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1581 molecular_function GO Molecular Function Annotations 2015 1.0 null endometrium_4a HPA Tissue Sample Gene Expression Profiles 1.0 2.51799 NDUFB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52905 ZXDB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3922 FAM53B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98029 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4828 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3729 LRFN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56189 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gonadotrophic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.986 POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.44842 TBXT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9205 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DOV13 CCLE Cell Line Gene CNV Profiles -1.0 -1.52654 RORA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2472 CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPVG-0326-SM-4B653 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11252 GTEX-S95S-1026-SM-4B64M GTEx Tissue Sample Gene Expression Profiles 1.0 0.824063 BRD4_01_119 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.395 GSE95077_5_v_0_amiloride_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04116 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055043 superficial stratum of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03015 GTEX-T8EM-0826-SM-4DM76 GTEx Tissue Sample Gene Expression Profiles 1.0 1.5581 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.79148 REST_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22675 CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 1 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.44557 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null interneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.424963 superficial stratum of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52027 lateral (dentate) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56772 GTEX-SN8G-0926-SM-4DM5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.05309 GSE211262,GSE211263_3_v_1_pbrm1_human RummaGEO Gene Perturbation Signatures 1.0 null APIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73086 GSE158969_1_v_2_trastuzumab_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QCQG-0426-SM-48U29 GTEx Tissue Sample Gene Expression Profiles 1.0 0.901141 CTCF_GM20000_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.906 GTEX-Q2AI-0426-SM-48U13 GTEx Tissue Sample Gene Expression Profiles 1.0 0.939978 MIGA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4327 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAMKK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58892 RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW1463 CCLE Cell Line Gene CNV Profiles -1.0 -1.36155 GSE216540_1_v_6_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null DPP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12565 BRIX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06304 SDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79693 MN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97218 Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null actomyosin COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.166167 GTEX-PW2O-1226-SM-48TCH GTEx Tissue Sample Gene Expression Profiles 1.0 0.994424 SFN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38785 CTDNEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78223 CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null Pancreatic beta cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.11 MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPVG-0526-SM-4B65N GTEx Tissue Sample Gene Expression Profiles 1.0 1.50086 GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 4.10893 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.843287 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SU-DHL-8 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.3057 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050947 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.937612 GTEX-T5JW-1126-SM-4DM5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.859526 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051894 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09659 Taenia tecta, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.06965 CTCF_GM12864_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06601 r9 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38249 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 1.98122 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.375 TBC1D25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76973 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13403 ORC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77766 regulation of calcium ion-dependent exocytosis GO Biological Process Annotations 2015 1.0 null PMC10592455-NIHMS1912792-supplement-4.xlsx-AHR_encode_CH22_overlap_2021101-ensembl_gene_id_AHR Rummagene Transcription Factor Associations 2026 1.0 null dorsolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23928 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE179031_3_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ALG6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46363 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.023 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVJ-1426-SM-48U1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.13889 Perturb_3282_KD_RORA_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3897 TAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5902 CRY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94589 SMAD3-18955504-HaCaT-human ChEA Transcription Factor Binding Site Profiles 1.0 null CCNT2 ENCODE Transcription Factor Targets 1.0 null CCNYL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34759 CTCF_astrocyte of the spinal cord_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67982 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.252 GSE145915_5_v_4_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18 NUPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57271 TSPAN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75252 ZEB1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DENND4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57904 subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.86905 GTEX-U8XE-0426-SM-3DB91 GTEx Tissue Sample Gene Expression Profiles 1.0 1.48245 PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR Rummagene Transcription Factor Associations 2026 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6687_KD_STAT3_SRP081918 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25003 hsa-miR-520b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 hsa-miR-4697-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 mediodorsal nucleus of thalamus_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.55382 MYRFL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0212 MC1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19267 CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06846 GTEX-XOT4-1426-SM-4B65T GTEx Tissue Sample Gene Expression Profiles 1.0 1.00703 orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.59764 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.931355 PMC12549544-mmc2.xlsx-AA_D7_VS_D14-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GHDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8236 EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POFUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.994 NCIH854 CCLE Cell Line Gene Expression Profiles 1.0 1.8472 Perturb_16533_KO_Cdk8_SRP351257 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.1162 CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE188382_4_v_0_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null establishment of synaptic vesicle localization GO Biological Process Annotations 2015 1.0 null CHAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96183 PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_5_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-548f TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 DAXX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41067 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ARID1A_01_114 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.62813 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZRANB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39771 GTEX-U8XE-1726-SM-4E3IF GTEx Tissue Sample Gene Expression Profiles 1.0 0.850444 hsa-miR-519d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE185744,GSE185747_2_v_3_sox9_human RummaGEO Gene Perturbation Signatures -1.0 null layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35516 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041948 PMC8986528-41586_2022_4598_MOESM11_ESM.xlsx-Extended_Data_Fig_6l-NOL9_KD_upreg_AR Rummagene Transcription Factor Associations 2026 1.0 null superior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.963841 RBM26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54489 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null TP53-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZEB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Hyperinsulinism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.036 ethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29968 496100315_TCx_no dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.55292 H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE118077_1_v_8_sprr5_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_2486_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 EIF3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38894 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE193993_1_v_7_sstr2_human RummaGEO Gene Perturbation Signatures -1.0 null glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.572662 GSE188870,GSE188871_0_v_5_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null MEX3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29703 GTEX-NPJ8-1926-SM-3MJGB GTEx Tissue Sample Gene Expression Profiles 1.0 0.964023 H3K4me3_Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NFIC_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FXYD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27057 SNU620 CCLE Cell Line Gene Expression Profiles 1.0 1.73948 PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR Rummagene Transcription Factor Associations 2026 1.0 null SNX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88386 BEN CCLE Cell Line Gene Expression Profiles 1.0 3.40788 GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles 1.0 1.08247 intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37652 mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null lung_4b HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE136311_1_v_0_lyz2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Eye-conjunctival epithelial cell Tabula Sapiens Gene-Cell Associations 1.0 8.90582 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ERV3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34765 PCDHB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.30381 P2RX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83389 SIN3A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3-22415368-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Neurosecretory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.595 short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.852835 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923995 ZNF746 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15254 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZEB1 ENCODE Transcription Factor Targets 1.0 null TEAD4_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4B-Supplemental_Table_S4B_Differentially_expressed_genes_upon_ZFX_Knock_down_in_MCF-7_ZFX Rummagene Transcription Factor Associations 2026 1.0 null 8MGBA CCLE Cell Line Gene Expression Profiles -1.0 -1.8832 Lung adenocarcinoma_LUAD_TCGA-50-6673-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IPMK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28509 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06601 GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 2.03294 ZNF202 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47465 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S4-Supplemental_Table_S4_Differentially_expressed_genes_between_cases_with_G-CSF-induced_pY-STAT3_DMFI_1_5_STAT3_Low_v_DMFI_1_5_STAT3_High_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null PMC9512540__F3 PFOCR Pathway Figure Associations 2024 1.0 null SMARCB1 ENCODE Transcription Factor Targets 1.0 null CTCF_fibroblast of gingiva_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3168 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 EGFL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09144 Principal sensory nucleus of the trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75021 Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THBS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17429 TAL1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD2-18955504-HaCaT-human ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-0926-SM-48TZK GTEx Tissue Sample Gene Expression Profiles 1.0 1.39962 MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5519 PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null TP53-22127205-IMR90-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JC-2526-SM-4DM6G GTEx Tissue Sample Gene Expression Profiles 1.0 2.06315 GTEX-X4XX-0011-R8B-SM-46MWM GTEx Tissue Sample Gene Expression Profiles 1.0 0.937876 pancreas TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.338545 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17929 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039812 FAM234A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8363 PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-27a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GTEX-OIZG-1326-SM-2HMIQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.02315 r6 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80452 organelle organization GO Biological Process Annotations 2015 1.0 null H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GAP43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81913 PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX Rummagene Transcription Factor Associations 2026 1.0 null endoplasmic GeneRIF Biological Term Annotations 1.0 null Diabetes DisGeNET Gene-Disease Associations 1.0 null nucleoplasm part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.059187 PSMD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24113 GSE132759_4_v_5_fgfr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27197 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CTCF_GM12865_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49375 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RELA ChEA Transcription Factor Targets 1.0 null FOXP1 ChEA Transcription Factor Targets 1.0 null TCF7L2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-106a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03977 MYH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69273 Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-149 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 PJA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24272 GTEX-OOBK-1026-SM-48TC2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26281 GTEX-U8T8-1226-SM-4E3IH GTEx Tissue Sample Gene Expression Profiles 1.0 1.31071 PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-402-CCDC79_TERB1 Rummagene Transcription Factor Associations 2026 1.0 null FOS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13935 CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PP-1026-SM-3NM9O GTEx Tissue Sample Gene Expression Profiles 1.0 0.981731 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71A-01A-22R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9003 PLCG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11083 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-302b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 regulation of acute inflammatory response GO Biological Process Annotations 2023 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13403 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21184 hsa-miR-1183 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44123 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.19853 GSE193993_1_v_2_sstr2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-UPK5-1126-SM-3GAEJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.07689 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CCDC163 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28846 GTEX-NL4W-0011-R9a-SM-2I3G1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.890434 mRNA_TCF7L2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.02 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042058 GTEX-WHSE-0011-R6A-SM-3P5ZP GTEx Tissue Sample Gene Expression Profiles 1.0 1.19312 PGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13476 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.917023 SMAD2 ChEA Transcription Factor Targets 1.0 null RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CLASP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58445 SNU668 CCLE Cell Line Gene Expression Profiles -1.0 -1.74456 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.15583 HT1080 DepMap CRISPR Gene Dependency 1.0 2.57769 OAW28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.86973 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.73627 neuroaxonal dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.06942 NCAN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70518 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05184 MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03693 DMRTC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.10364 Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2063 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.832 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WN-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EMX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12962 ethanol_mus musculus_gpl6105 _gds3703 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6828-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HELA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22992 EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09184 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15547_KO_Ar_SRP069731 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GTEX-X4EP-0826-SM-3P5YK GTEx Tissue Sample Gene Expression Profiles 1.0 1.41933 HS6ST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94448 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PLAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91263 GTEX-P4QR-0726-SM-2I5GO GTEx Tissue Sample Gene Expression Profiles 1.0 0.850476 intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null calcium ion-dependent exocytosis of neurotransmitter GO Biological Process Annotations 2015 1.0 null PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7 Rummagene Transcription Factor Associations 2026 1.0 null DNAJC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24412 CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VPS4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39018 DPH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94262 regulation of secretion by cell GO Biological Process Annotations 2015 1.0 null Basolateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12712 DDX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52068 YMB1 CCLE Cell Line Gene Expression Profiles 1.0 1.57276 regulation of localization GO Biological Process Annotations 2015 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null GTEX-NL4W-0011-R4a-SM-2I5GZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.0751 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03752 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 0.88968 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053285 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.242 GTEX-PLZ6-0226-SM-3P61I GTEx Tissue Sample Gene Expression Profiles 1.0 1.15978 LS 180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.624 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HUO9 DepMap CRISPR Gene Dependency 1.0 2.61678 Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.08 IMPDH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45435 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.00692 actin filament bundle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.211587 LIPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51741 Perturb_14397_KD_XPR1_SRP347870 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.37763 GSE234340_4_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24579 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SALL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82052 GSE229671,GSE229673_2_v_1_yrdc_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null plasma membrane GO Cellular Component Annotations 2015 1.0 null hsa-miR-3199 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 CCFSTTG1 CCLE Cell Line Gene Expression Profiles -1.0 -1.96799 mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0137 Suprachiasmatic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.917 ZBTB20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88073 CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE184210_0_v_1_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null Nucleus ambiguus, ventral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45329 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043619 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60041 RWDD2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37059 GTEX-WFG7-1326-SM-4LMK1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32701 ZNF616 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3066 Primary somatosensory area, lower limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56386 skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 hsa-miR-3198 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 caudate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5276 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06691 CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XAJ8-0526-SM-47JYK GTEx Tissue Sample Gene Expression Profiles 1.0 1.35455 HEY1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9287 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46617 SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02417 E2F6_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.91119 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980526 Uterus GTEx Tissue Gene Expression Profiles 2023 1.0 1.06014 FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.4728 SKNFI CCLE Cell Line Gene CNV Profiles 1.0 1.45684 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null transport GO Biological Process Annotations 2015 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32594 intracellular part LOCATE Curated Protein Localization Annotations 1.0 null PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2 Rummagene Transcription Factor Associations 2026 1.0 null CTSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67338 STEAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3331 CH157MN DepMap CRISPR Gene Dependency 1.0 2.58421 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.874025 GATA2_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF354B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55048 HCT-8 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.612 PCGF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90308 SUZ12 ENCODE Transcription Factor Targets 1.0 null single-organism cellular process GO Biological Process Annotations 2015 1.0 null ZBTB32 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6912 STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19324 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REST_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3161 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46736 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35975 interstitial nucleus of the zona limitans Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19324 Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q734-1026-SM-48U16 GTEx Tissue Sample Gene Expression Profiles 1.0 1.53723 hsa-miR-3163 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GTEX-WYVS-0526-SM-3NM9W GTEx Tissue Sample Gene Expression Profiles 1.0 1.22521 delivers GeneRIF Biological Term Annotations 1.0 null posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05047 NEK9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69767 POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68334 DAAM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87991 CTCF_GM12874_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUN-27471255-CHONDROCYTES-MOUSE-RIB ChEA Transcription Factor Targets 2022 1.0 null C4orf36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65416 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39933 GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 2.64948 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-SNOS-0926-SM-4DM7A GTEx Tissue Sample Gene Expression Profiles 1.0 1.02308 CHDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68716 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2482_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SLC37A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37905 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053992 H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.093295 hsa-miR-202 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 localization GO Biological Process Annotations 2015 1.0 null CILK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.82461 ZNF580 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.47541 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.969038 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MP-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZSCAN23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28891 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.74815 Breast - Mammary Tissue GTEx Tissue Gene Expression Profiles 2023 1.0 6.9285 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAB3GAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58578 PTPN13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98953 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78632 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.04829 MYOG_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38048 r8 part of linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86032 GTEX-U4B1-1026-SM-4DXT1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.73402 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null DCAF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02689 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHSE-1126-SM-3NMBU GTEx Tissue Sample Gene Expression Profiles 1.0 1.2699 GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 1.21581 Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null nucleotide GeneRIF Biological Term Annotations 1.0 null H3K27me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04884 H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.67906 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.957493 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WI4N-0726-SM-3TW93 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0298 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44576 KDM5B ENCODE Transcription Factor Targets 1.0 null CTCF_GM12875_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VUSG-0126-SM-4KL1X GTEx Tissue Sample Gene Expression Profiles 1.0 2.91348 HEATR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03876 GTEX-PWOO-1326-SM-48TCJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.62436 colorectum TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_2487_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE130437_0_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null MIM complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.574 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.1743 hsa-miR-372 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 H3K27me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cell part LOCATE Curated Protein Localization Annotations 1.0 null DUSP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4391 GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 1.59432 nucleus LOCATE Curated Protein Localization Annotations 1.0 null lateral septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08453 GTEX-WHSE-0011-R4A-SM-3P5ZN GTEx Tissue Sample Gene Expression Profiles 1.0 1.13944 GTEX-Q2AG-0326-SM-48U1O GTEx Tissue Sample Gene Expression Profiles 1.0 0.884821 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5375 GSE188382_4_v_1_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null AM38 DepMap CRISPR Gene Dependency 1.0 2.18016 ERA-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE186287_1_v_3_ufm1_human RummaGEO Gene Perturbation Signatures -1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null TOE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45118 Perturb_6670_KO_FGFR4_SRP386785 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.7984 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12864_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE150669_2_v_3_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-23a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 HCC1500 CCLE Cell Line Gene CNV Profiles -1.0 -1.4811 acute inflammatory response GO Biological Process Annotations 2023 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84715 Perturb_14398_KO_SYK_SRP124678 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.6329 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SSP25 DepMap CRISPR Gene Dependency 1.0 2.73956 JARID2-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.01266 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Collagen sheet COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.605 GSE174701_1_v_7_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null MON1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24841 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.57792 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE145915_5_v_1_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC9975294-mmc3.xlsx-Silent_TPIT_velocity_genes-gene_TBX19 Rummagene Transcription Factor Associations 2026 1.0 null NCIH2126 CCLE Cell Line Gene Expression Profiles 1.0 1.39938 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PEA15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67979 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ventropallial prepiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02747 G59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60317 MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal peduncular area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11813 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-23b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 enzalutamide_homo sapiens_gpl570_gse44905 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null r2 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67051 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null polymorphism GeneRIF Biological Term Annotations 1.0 null RELA-24523406-FIBROSARCOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.838955 GTEX-WI4N-2726-SM-3LK7Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.05397 Primary somatosensory area, lower limb, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16301 GBGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12307 posteroventral (inferior) parietal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38607 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.993136 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41618 KD DepMap CRISPR Gene Dependency 1.0 2.17077 SDF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81457 Arcuate hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06101 Lung squamous cell carcinoma_LUSC_TCGA-85-8351-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04 PMC10806738-mmc2.xlsx-Table_S1-Table_S1_Table_of_significantly_adjusted_p-valued_0_05_up-regulated_genes_log2FC_1_in_MAX-R60Q_transfected_HEK293_cells_relative_to_MAX-WT_transfected_cells_MAX Rummagene Transcription Factor Associations 2026 1.0 null H3K23ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null periventricular stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52856 H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE149880_0_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9615 TP53I3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10307 PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null intermediate stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51925 T3M3 DepMap CRISPR Gene Dependency 1.0 4.33278 establishment of organelle localization GO Biological Process Annotations 2015 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZDHHC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68156 UBE2R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36596 GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.38594 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03648 ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletalmuscle_a HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 GSE116299_4_v_3_folic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE216538_1_v_3_mrs2_mouse RummaGEO Gene Perturbation Signatures 1.0 null mantle zone of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02417 Perturb_3580_KD_UBE3A_SRP124518 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.4155 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12871_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4439 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE161864,GSE161866_4_v_3_ror2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.41506 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null NR1I2 ChEA Transcription Factor Targets 1.0 null r2 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27778 TMEM222 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56161 syntaxin binding GO Molecular Function Annotations 2015 1.0 null hsa-miR-134 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 MT-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37798 JHUEM7 DepMap CRISPR Gene Dependency 1.0 2.71276 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null posterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32122 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85109 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22343 ChIP_JARID2_20075857 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H376 DepMap CRISPR Gene Dependency 1.0 2.60803 ZC3H11A ENCODE Transcription Factor Targets 1.0 null GATA1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HCC1143 CCLE Cell Line Gene CNV Profiles 1.0 1.41387 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.203275 GTEX-S33H-1626-SM-4AD68 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57415 AP1M1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18684 SYNCRIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65202 MAX_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RVH421SKINFV1 DepMap CRISPR Gene Dependency 1.0 2.48013 H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null UPCISCC026 DepMap CRISPR Gene Dependency 1.0 2.13272 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.16891 TAL1_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE149903_6_v_1_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF2 ENCODE Transcription Factor Targets 1.0 null AASS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4093 NANOG_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVJ-1226-SM-48U1V GTEx Tissue Sample Gene Expression Profiles 1.0 1.13377 SMPD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93305 BMI1 ChEA Transcription Factor Targets 1.0 null UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null RAC3-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null p1B part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48205 ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7422 hsa-miR-302d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GTEX-S32W-0926-SM-4AD5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.89229 ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14478 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.35881 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.0088 intermediate stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07284 GSE192870_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-3065-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.61597 Ventral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09659 MAFK_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2785 DSG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98829 GTEX-U8XE-1026-SM-4E3HM GTEx Tissue Sample Gene Expression Profiles 1.0 2.04695 GSE158834_0_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41515 hsa-miR-4539 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null increased mean platelet volume IMPC Knockout Mouse Phenotypes 1.0 null GTEX-UJHI-0626-SM-3DB8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.47852 GATA1_G1E-ER4_mm9_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12867_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null lipid binding GO Molecular Function Annotations 2015 1.0 null laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.887057 RPL18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55627 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE128076_1_v_3_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null dorsomedial preoptic area, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04796 r9 part of the lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93798 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.917411 hsa-miR-499-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null intermediate mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22148 RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QESD-0626-SM-2I5G4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.94215 JADE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.95961 autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.39598 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8312-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03752 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48088 TCF12_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RD CCLE Cell Line Gene CNV Profiles -1.0 -2.44169 CYBRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.58902 cellular_component GO Cellular Component Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-A479-01A-31R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16433 periventricular stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48525 CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM147 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32698 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9179018-NIHMS1792335-supplement-Supplementary_Tables.xlsx-ST18-Unnamed_7_ST18 Rummagene Transcription Factor Associations 2026 1.0 null appendices_4a HPA Tissue Sample Gene Expression Profiles 1.0 0.828329 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18 H3K27me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5715-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07582 GTEX-XV7Q-0926-SM-4BRVQ GTEx Tissue Sample Gene Expression Profiles 1.0 2.07661 mantle zone of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17438 periventricular stratum of p1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52678 TRIM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45218 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051121 positive regulation of inflammatory response GO Biological Process Annotations 2023 1.0 null KP4 CCLE Cell Line Gene CNV Profiles 1.0 1.81962 EBC1 CCLE Cell Line Gene CNV Profiles 1.0 2.14264 CDKN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43257 Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A9DB-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POGLUT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26761 GSE118794_5_v_4_zmynd8_mouse RummaGEO Gene Perturbation Signatures 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null MOSMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86251 PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-genename_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CR-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1651 CCLE Cell Line Gene CNV Profiles 1.0 1.9767 RAD21_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-154 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HEK293_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE150669_2_v_1_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null GPAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30707 CILP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69257 GSE158834_10_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dexamethasone_homo sapiens_gpl570_gse37474 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -1.45247 PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.862523 TAL1_megakaryocyte_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_435_TCF7_rep1_sorted_pea-Gene_Name_TCF7 Rummagene Transcription Factor Associations 2026 1.0 null MRPL28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6369 JMSU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.52705 striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.57511 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050887 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null posteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50249 SOHLH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6538 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null nuclear lumen GO Cellular Component Annotations 2023 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASCL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82826 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.84789 SCARA5_Down Expression_GSE32323_611_human_Colorectal Cancer Cell lines GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Parahippocampal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.737 POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKMEL3 CCLE Cell Line Gene CNV Profiles 1.0 1.50968 FZR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22105 GTEX-X261-3226-SM-3NMC3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.78303 ELN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24352 GTEX-QDVN-0826-SM-48TZ2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.986128 Pancreatic islet cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.103 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG7-0426-SM-4LMK5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13234 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE186280_1_v_0_sorafenib_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-520e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 SHP77 CCLE Cell Line Gene Expression Profiles 1.0 1.96109 GSE128634,GSE128636_4_v_0_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null ANKRD50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83032 viscus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PLEKHH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15489 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null thalamic (p2) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61071 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.8636 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-23c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63774 ANO9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39303 GSE249098_3_v_0_mthfd1l_human RummaGEO Gene Perturbation Signatures 1.0 null FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.2037 Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.22583 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16888 pituitary GTEx Tissue Gene Expression Profiles 1.0 1.92403 skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5331-01A-02R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null r8 part of lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.42229 RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null 20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE181513_2_v_1_usp7_human RummaGEO Gene Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34307 EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.845382 ZFP90 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5192 TCCSUP CCLE Cell Line Gene Expression Profiles -1.0 -1.67605 H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null golgi apparatus LOCATE Predicted Protein Localization Annotations 1.0 null CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5883-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9 Rummagene Transcription Factor Associations 2026 1.0 null SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64358 TIG3TD CCLE Cell Line Gene Expression Profiles -1.0 -1.63807 TBC1D22B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93785 mRNA_SMAD7_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null signal release GO Biological Process Annotations 2015 1.0 null mantle zone of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23496 JUND_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.65896 MT-ND4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28111 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Eye-radial glial cell Tabula Sapiens Gene-Cell Associations 1.0 1.18661 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0549 HH CCLE Cell Line Gene CNV Profiles -1.0 -2.43162 H3K27me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U8XE-1226-SM-4E3HN GTEx Tissue Sample Gene Expression Profiles 1.0 1.24651 ZNF507 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59557 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.839178 membrane GO Cellular Component Annotations 2015 1.0 null PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4E-Supplemental_Table_S4E_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_MCF-7_ZFX Rummagene Transcription Factor Associations 2026 1.0 null TRIM23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.36486 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100586_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 13.2912 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043337 RAB42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43168 ARHGEF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05506 Perturb_2480_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NET1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93778 CTCF_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FBLN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67381 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25319 CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_11743_KD_Nsd2_SRP312884 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.37506 HNF4G ENCODE Transcription Factor Targets 1.0 null hsa-miR-449b TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 UBN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66564 H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE106661,GSE106665_0_v_3_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-221 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-29c TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 H2BC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17102 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02876 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-758 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 2.44561 GSE143782_7_v_11_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2322 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null OPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53061 ATP6AP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64522 SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE241108_1_v_0_sulfasalazine_human RummaGEO Drug Perturbation Signatures 1.0 null spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.868674 L-428 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC10290283-biol-2022-0622-sm3.pdf-91-HEY2_HEY2 Rummagene Transcription Factor Associations 2026 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15296 CAPAN-1 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 SNU878 CCLE Cell Line Gene Expression Profiles 1.0 1.45029 GTEX-PSDG-1526-SM-48TCY GTEx Tissue Sample Gene Expression Profiles 1.0 1.89233 U266B1 CCLE Cell Line Gene CNV Profiles 1.0 1.38494 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.917411 Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27472 ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletalmuscle_d HPA Tissue Sample Gene Expression Profiles -1.0 -1.08911 RAD21-21589869-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GRHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4834 hsa-miR-3646 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null GSE234340_12_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_3285_KD_RORC_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE137914_0_v_1_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null ALPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41163 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LMX1B_LMX1B Rummagene Transcription Factor Associations 2026 1.0 null ZNF132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99372 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32367 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12818133-mmc1.pdf-10-MAFB_MAFB Rummagene Transcription Factor Associations 2026 1.0 null GRSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6702 GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.6248 PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tuberomammillary nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08355 establishment of localization in cell GO Biological Process Annotations 2015 1.0 null REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6518 ATP6V0A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07681 mantle zone of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28284 GSE188870,GSE188871_1_v_5_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null TE4 CCLE Cell Line Gene CNV Profiles 1.0 1.38887 GSE229671,GSE229673_3_v_1_yrdc_human RummaGEO Gene Perturbation Signatures 1.0 null ZNF343 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92054 ZNRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82246 LHX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60777 ANKRD40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05385 hsa-miR-199a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.74759 GTEX-XYKS-1226-SM-4BRVI GTEx Tissue Sample Gene Expression Profiles 1.0 1.28042 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of neurotransmitter levels GO Biological Process Annotations 2015 1.0 null H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RM2N-0826-SM-48FD3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.826894 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41952 PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1 Rummagene Transcription Factor Associations 2026 1.0 null APPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92487 ACVR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62299 NKX6-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76716 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null SETDB1 ENCODE Transcription Factor Targets 1.0 null PHF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82433 brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.056615 RPMI8226 CCLE Cell Line Gene CNV Profiles 1.0 1.43677 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SH3BP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26681 AR ChEA Transcription Factor Targets 1.0 null MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4469 Lung squamous cell carcinoma_LUSC_TCGA-85-8664-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18389 H3K27me3_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3136-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSU CCLE Cell Line Gene Expression Profiles 1.0 1.67868 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.868166 Parahippocampal region TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.163 VEGFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47288 PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null lateral part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23379 GTEX-PLZ6-0726-SM-3P619 GTEx Tissue Sample Gene Expression Profiles 1.0 0.911391 GTEX-QDVN-1326-SM-48TZ3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.925589 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29089 Perturb_15199_KD_ADA2_SRP266202 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.8858 UQCRQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78244 REST_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSME2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07722 RING1B-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null FOXM1-26456572-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GATA1-19941827-MEL86-MOUSE ChEA Transcription Factor Targets 2022 1.0 null central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.952663 REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0 AP1S2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95469 cerebral cortical neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.451813 TOMM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40986 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.73099 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53682 ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.20708 E2F4_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF331 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6574 Lip TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.705 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZBTB12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15133 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null E2F6_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OST4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.42239 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSDMB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17401 GTEX-XXEK-1026-SM-4BRUW GTEx Tissue Sample Gene Expression Profiles 1.0 1.21775 SETDB1_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-384 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 posteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70452 cajal body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.510011 GSE118548_1_v_3_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCILY18 DepMap CRISPR Gene Dependency 1.0 3.0118 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893512 ELK1 ENCODE Transcription Factor Targets 1.0 null BARHL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43048 r2 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57801 YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null diabetes GeneRIF Biological Term Annotations 1.0 null H4K20me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r9 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14811 ventral lateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29318 SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE226115,GSE226116_1_v_0_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-515-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 CREB1 ENCODE Transcription Factor Targets 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.941245 NSUN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60705 anterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20957 sclc21h HPA Cell Line Gene Expression Profiles 1.0 1.23117 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GID4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47758 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSTA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3277 REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.64 GSE199092_3_v_0_ddx5_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q734-0626-SM-2I3EF GTEx Tissue Sample Gene Expression Profiles 1.0 1.01211 PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF Rummagene Transcription Factor Associations 2026 1.0 null ZNF385C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67873 membrane organization GO Biological Process Annotations 2015 1.0 null Dorsal peduncular area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06305 GTEX-O5YT-1026-SM-3MJGF GTEx Tissue Sample Gene Expression Profiles 1.0 1.17637 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57848 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CBX3 ENCODE Transcription Factor Targets 1.0 null nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.073755 RUNX1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cerebral degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.235616 TPSG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79535 REST_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null neurotransmitter secretion GO Biological Process Annotations 2015 1.0 null GTEX-T5JW-1526-SM-4DM5E GTEx Tissue Sample Gene Expression Profiles 1.0 1.12569 CTCF_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE185944_0_v_3_pth1r_mouse RummaGEO Gene Perturbation Signatures -1.0 null SKRC31 DepMap CRISPR Gene Dependency 1.0 3.35808 GTEX-X4XY-1626-SM-46MVN GTEx Tissue Sample Gene Expression Profiles 1.0 1.57369 GTEX-QEL4-1326-SM-447AD GTEx Tissue Sample Gene Expression Profiles 1.0 0.855509 ETV3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1696 GSE111035,GSE111040_8_v_9_plag1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4764-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.57676 EBF1 ENCODE Transcription Factor Targets 1.0 null RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.917411