association dataset threshold value standardized value interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.925944 Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8214_KD_SRSF5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.22106 growth abnormality GWASdb SNP-Phenotype Associations 1.0 0.360889 GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935504 GTEX-OXRO-0011-R2A-SM-3NB1W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88497 CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.848936 Perturb_17612_OE_MYC_SRP301619 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.83983 inherited metabolic disorder GWASdb SNP-Disease Associations 1.0 0.314111 mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.41932 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20345 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.856093 Perturb_10039_KD_UBE2L3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.78141 ZZEF1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49279 GTEX-QXCU-0626-SM-2TC69 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12154 GTEX-XOTO-0008-SM-4GICE GTEx Tissue Sample Gene Expression Profiles 1.0 0.830905 FLNA Pathway Commons Protein-Protein Interactions 1.0 null SJRH30 CCLE Cell Line Gene Expression Profiles 1.0 1.97309 CNOT11 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33074 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64902 TE1 CCLE Cell Line Gene CNV Profiles 1.0 2.00752 DIRAS2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15870_KD_NRAS_SRP328367 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.33611 GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09926 Perturb_9928_KD_SRSF7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.00708 GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842168 GTEX-PLZ5-0326-SM-3P614 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16783 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68735 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null orbital frontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.992972 Perturb_14356_KD_TUT7_SRP120600 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.8118 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.99048 Triglycerides dbGAP Gene-Trait Associations 1.0 0.113085 PKM Pathway Commons Protein-Protein Interactions 1.0 null GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48326 Perturb_15491_KO_BCOR_SRP168753 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.47764 H3K9me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CAPAN1 CCLE Cell Line Gene CNV Profiles 1.0 1.33522 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06193 H3K9me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972404 schizophrenia GWASdb SNP-Disease Associations 1.0 0.681692 FOSL2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_1992_OE_IRX5_SRP357294 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.19918 musculoskeletal system disease GWASdb SNP-Disease Associations 1.0 0.250109 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11042 Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_265_OE_DPF3a_SRP322020 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.31228 IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11128 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.58007 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAMD9L Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-3612 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 HCC1195 CCLE Cell Line Gene CNV Profiles 1.0 1.60511 Perturb_10001_KD_FMR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.14189 GTEX-WHSB-1626-SM-3LK6J GTEx Tissue Sample Gene Expression Profiles 1.0 0.94114 MTRF1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6262_KD_NDP_SRP188348 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.63316 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A4C1-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CENPV Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12192_KD_HPRT1_SRP259972 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.45325 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13712 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.55226 GTEX-Q734-0006-SM-2I3FJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00484 Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CSF1 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZM-0926-SM-4DXSW GTEx Tissue Sample Gene Expression Profiles 1.0 1.12992 Perturb_10034_KD_PUF60_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.22566 SERPINH1 Pathway Commons Protein-Protein Interactions 1.0 null HCC2157 CCLE Cell Line Gene CNV Profiles 1.0 1.66289 PDLIM4 Pathway Commons Protein-Protein Interactions 1.0 null TE-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.76305 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.86271 GTEX-OIZI-0008-SM-2XCFD GTEx Tissue Sample Gene Expression Profiles 1.0 1.28715 rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.986087 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.67986 glucose metabolism disease GWASdb SNP-Disease Associations 1.0 1.48714 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20345 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.5427 RIMS2 Pathway Commons Protein-Protein Interactions 1.0 null testis HPA Tissue Protein Expression Profiles 1.0 0.733372 GTEX-QDVN-1226-SM-48TZ5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15373 U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10545 GTEX-W5WG-1926-SM-4KKZK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.944056 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.46005 Perturb_7864_KD_YTHDC1_SRP226173 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.29394 Perturb_2590_OE_NFIB_SRP100638 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.47939 GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 H3K9me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_15210_OE_MIR130A_SRP373399 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.36658 striatum_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.83864 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88034 ETV3 Pathway Commons Protein-Protein Interactions 1.0 null MAP3K7 Pathway Commons Protein-Protein Interactions 1.0 null BHT101 CCLE Cell Line Gene Expression Profiles -1.0 -1.67723 Perturb_754_OE_METTL3_SRP393226 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.83622 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07689 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WX-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.42483 HDAC1 ENCODE Transcription Factor Targets 1.0 null Perturb_14886_KO_H13_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.91437 USP48 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 2.46833 Perturb_9920_KD_NELFE_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.52461 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.03606 GTEX-PSDG-1126-SM-2S1ON GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.0088 nutrition disease GWASdb SNP-Disease Associations 1.0 0.487532 H3K9me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-S4Q7-1026-SM-4AD75 GTEx Tissue Sample Gene Expression Profiles 1.0 0.829671 GTEX-S341-0226-SM-2XCAX GTEx Tissue Sample Gene Expression Profiles 1.0 1.01674 JURKAT, CLONE E6-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GTEX-P4QS-0008-SM-48TDY GTEx Tissue Sample Gene Expression Profiles 1.0 1.21975 vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-T2IS-1026-SM-32QP1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06282 PRG4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.964545 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25908 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.71497 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55062 muscular disease GWASdb SNP-Disease Associations 1.0 0.297275 abnormality of the coagulation cascade GWASdb SNP-Phenotype Associations 1.0 1.41367 Lung adenocarcinoma_LUAD_TCGA-78-7536-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAG1 Pathway Commons Protein-Protein Interactions 1.0 null amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02459 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10281 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.63846 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0826 GTEX-XV7Q-1426-SM-4BRWA GTEx Tissue Sample Gene Expression Profiles 1.0 1.2404 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMK1-0226-SM-4B65D GTEx Tissue Sample Gene Expression Profiles 1.0 0.938974 GTEX-OXRP-0126-SM-3NB32 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.951494 KIF12 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59714 GTEX-S341-0126-SM-4AD64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06419 GTEX-VJYA-1026-SM-4KL21 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23079 Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.56208 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IH-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8091_KD_NOL12_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.38027 heart muscle HPA Tissue Protein Expression Profiles 1.0 0.733372 XYLT1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8147_KD_KRR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.81139 GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 CPSF2 Pathway Commons Protein-Protein Interactions 1.0 null abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.043006 SMC6 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86015 Perturb_17807_KO_ZNF675_SRP304971 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.56733 Perturb_2557_KD_NXF1_SRP226431 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.18142 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01846 GTEX-T5JW-1626-SM-3GADZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06487 Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null M059K CCLE Cell Line Gene CNV Profiles -1.0 -1.47232 GTEX-OIZG-0005-SM-2HMJC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31238 ITGAL Pathway Commons Protein-Protein Interactions 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.18589 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DDX51 Pathway Commons Protein-Protein Interactions 1.0 null primary motor-sensory cortex (samples)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05047 H3K9me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null schizophrenia GWASdb SNP-Phenotype Associations 1.0 0.58403 H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HS 695T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23995 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5361-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03855 SKNBE2 CCLE Cell Line Gene CNV Profiles 1.0 1.47569 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02473 GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34577 Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-REY6-1226-SM-48FDR GTEx Tissue Sample Gene Expression Profiles 1.0 0.885786 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43106 adrenal gland GTEx Tissue Gene Expression Profiles 1.0 1.3271 SMYD4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.880208 WDFY3 Pathway Commons Protein-Protein Interactions 1.0 null Arthritis DisGeNET Gene-Disease Associations 1.0 null GTEX-S7SF-2026-SM-3K2AS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14822 GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.987145 GTEX-UPK5-0008-SM-4IHJD GTEx Tissue Sample Gene Expression Profiles 1.0 0.978111 Perturb_7203_KD_DHX9_SRP080966 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.4261 Perturb_13495_KD_IGF2BP1_SRP291710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.97385 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.874445 H3K9me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24972 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.09291 GTEX-O5YV-1126-SM-3LK73 GTEx Tissue Sample Gene Expression Profiles 1.0 0.968182 Lung squamous cell carcinoma_LUSC_TCGA-94-8035-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.248122 Perturb_3626_KO_HDAC1_SRP355605 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.35657 GTEX-O5YW-0126-SM-3LK6D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.885828 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.50172 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.931463 BPTF Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8998_KD_lnc Cyrano_SRP261325 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.98064 PLEKHH1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6481_KD_SERBP1_ERP118886 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.14401 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.975354 HH CCLE Cell Line Gene CNV Profiles 1.0 1.35354 20min_EGF vs ctrl_HeLa (Human) [17081983] SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands -1.0 null Perturb_13678_KD_DHX9_SRP018815 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.942662 GTEX-V1D1-0926-SM-4JBHQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.944314 intracellular part GO Cellular Component Annotations 2015 1.0 null GTEX-S3XE-0126-SM-4AD4R GTEx Tissue Sample Gene Expression Profiles 1.0 1.2278 Prostate adenocarcinoma_PRAD_TCGA-CH-5766-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06391 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.100938 GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles 1.0 1.37716 GTEX-S341-0626-SM-4AD5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.201 H3K9me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QV31-0726-SM-3GAEG GTEx Tissue Sample Gene Expression Profiles 1.0 0.950068 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EB-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUPT1 CCLE Cell Line Gene Expression Profiles 1.0 1.93643 TUBA4A Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23L-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XY-1626-SM-46MVN GTEx Tissue Sample Gene Expression Profiles 1.0 1.00022 PREX2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9823_KD_TAL1_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.18777 Perturb_8135_KD_G3BP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.0601 OVISE CCLE Cell Line Gene CNV Profiles 1.0 2.37732 TENC1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 2.04444 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824306 PRKAR1B Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29005 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.932665 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865223 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A66Y-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU61 CCLE Cell Line Gene CNV Profiles -1.0 -1.32908 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60414 GTEX-WL46-0626-SM-3LK7R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19564 Brain Lower Grade Glioma_LGG_TCGA-TM-A84C-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7865_KO_SDE2_SRP239880 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.54191 GTEX-Q2AI-1526-SM-3GIJ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.96217 Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X88G-0006-SM-47JX5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900387 Perturb_8089_KD_HNRNPA2B1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.0406 AGK Pathway Commons Protein-Protein Interactions 1.0 null upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5109 Bladder Urothelial Carcinoma_BLCA_TCGA-FT-A61P-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_520_KD_RNF113A_SRP201913 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.59638 GTEX-R55D-0626-SM-3GAD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42549 GTEX-Q734-2026-SM-3GADA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.954605 Lung adenocarcinoma_LUAD_TCGA-50-6673-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3593_KO_HRI_SRP218218 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.51417 CCM2L Pathway Commons Protein-Protein Interactions 1.0 null midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20481 Lung adenocarcinoma_LUAD_TCGA-55-7911-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Triglycerides Measurement DisGeNET Gene-Phenotype Associations 1.0 null GTEX-OIZI-0426-SM-2XCEF GTEx Tissue Sample Gene Expression Profiles 1.0 0.878087 GTEX-XYKS-0926-SM-4BRVG GTEx Tissue Sample Gene Expression Profiles 1.0 1.41351 Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bronchus HPA Tissue Protein Expression Profiles 1.0 0.733372 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.916413 GTEX-REY6-0426-SM-2TF5G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.89737 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.814 psychotic disorder GWASdb SNP-Disease Associations 1.0 0.281032 EB1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.911085 hematopoietic system disease GWASdb SNP-Disease Associations 1.0 0.207672 CNTN5 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4964_KO_WWOX_SRP277498 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.48602 Perturb_437_KO_HNRNPA2B1_SRP067568 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.39324 GTEX-OHPK-1526-SM-3MJGM GTEx Tissue Sample Gene Expression Profiles 1.0 1.29372 Perturb_12148_OE_CENPA_ERP125655 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.11693 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.962906 anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.99492 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66486 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.876692 GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33507 C4A Pathway Commons Protein-Protein Interactions 1.0 null L1236 CCLE Cell Line Gene CNV Profiles 1.0 1.87805 GTEX-U4B1-1626-SM-3DB8N GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 KIAA0922 Pathway Commons Protein-Protein Interactions 1.0 null MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07951 Perturb_3793_KD_SNTA1_SRP057613 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.64445 GTEX-TMMY-0126-SM-4DXTP GTEx Tissue Sample Gene Expression Profiles 1.0 0.949685 HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.51754 HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -2.45819 Perturb_436_KO_HNRNPA1_SRP067568 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.84553 H3K9me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-SIU8-0006-SM-2XCE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06547 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y0-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOT4-0008-SM-4B664 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879109 SETX Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6444_KO_MRTFA_SRP134183 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.13234 GTEX-SJXC-1226-SM-4DM78 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44287 Perturb_7912_KO_RNPC3_SRP367036 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 MUC5AC Pathway Commons Protein-Protein Interactions 1.0 null Perturb_14629_KO_MSLN_SRP199242 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.84917 sclc21h HPA Cell Line Gene Expression Profiles 1.0 2.65102 Perturb_6764_KO|KD_SERPINE2_SRP103746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.99489 Perturb_10355_KD_SHQ1_SRP154234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CD56+_NKCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.04043 GTEX-QEL4-0008-SM-447AZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.906533 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.933827 GTEX-QDT8-0011-R2A-SM-32PKQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.09883 BICR 10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05556 Perturb_13957_KO_YAP1_SRP194022 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.10674 H3K9me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_8177_KD_RPS3A_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.43397 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01791 GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07676 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8142_KD_MATR3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.89631 GTEX-PLZ4-0226-SM-2S1NW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 GTEX-RWS6-1026-SM-47JXD GTEx Tissue Sample Gene Expression Profiles 1.0 1.33418 Perturb_6759_KO|KD_IER5_SRP103746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.4622 Perturb_13959_KO_YAP1_SRP194022 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.12094 Perturb_7153_KD_MOV10_SRP029367 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.31341 LRP1B Pathway Commons Protein-Protein Interactions 1.0 null Perturb_13906_KD_TARDBP_SRP102807 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.30768 Perturb_7631_KD_AF4_SRP078067 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.60214 ZC3H18 Pathway Commons Protein-Protein Interactions 1.0 null MDAMB415 CCLE Cell Line Gene CNV Profiles -1.0 -1.82831 Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11387_OE_OC2_SRP122890 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.86359 Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3132 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7100-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.895523 GTEX-RU72-0011-R9A-SM-2TF67 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.916988 H2AFZ Pathway Commons Protein-Protein Interactions 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.93902 GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 IZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.896984 BL5930 (SPAG5) NURSA Protein Complexes 1.0 null ERP44 Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.32427 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.56354 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.14744 PPIP5K2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_82_KD_HOXC4_SRP192852 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.8228 NCIH2052 CCLE Cell Line Gene CNV Profiles 1.0 1.84779 KLF10 Pathway Commons Protein-Protein Interactions 1.0 null T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27958 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14359 BC3C CCLE Cell Line Gene CNV Profiles -1.0 -1.63592 GTEX-TSE9-0726-SM-3DB8C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963422 HS822T CCLE Cell Line Gene Expression Profiles -1.0 -1.83772 ZBTB40 Pathway Commons Protein-Protein Interactions 1.0 null FZD10 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_10078_KD_ZC3H8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.10368 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.65633 H3K9me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null vascular disease GWASdb SNP-Disease Associations 1.0 0.361262 NCOR2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6763_KO|KD_SERPINE2_SRP103746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.56927 GTEX-WK11-2526-SM-3NM9Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.913327 Perturb_9919_KD_MATR3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.65971 LGALS7B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X4EO-2926-SM-4E3JH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877406 Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX2 JASPAR Predicted Transcription Factor Targets 1.0 null NPC1L1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8493_KD_MBNL1_ERP115267 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.85877 Perturb_2382_KD_ERBB2_SRP045322 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.04705 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.64154 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Perturb_8231_KD_PRPF4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.00112 SNU1076 CCLE Cell Line Gene Expression Profiles 1.0 1.55068 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02806 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-V955-0426-SM-3GAEL GTEx Tissue Sample Gene Expression Profiles 1.0 0.861046 Perturb_3595_KO_HRI_SRP218218 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.93858 Perturb_8324_KD_INO80_SRP103083 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.88079 SHANK2 Pathway Commons Protein-Protein Interactions 1.0 null H3K9me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HIST1H2BM Pathway Commons Protein-Protein Interactions 1.0 null HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15435 Perturb_98_KD_INTS8_SRP262320 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 KALRN Pathway Commons Protein-Protein Interactions 1.0 null C20orf57 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10573 NB1 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 A2780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3241 Perturb_2290_OE_TBX3_SRP184219 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.20528 CALCOCO2 Pathway Commons Protein-Protein Interactions 1.0 null SMTN Pathway Commons Protein-Protein Interactions 1.0 null molt4 HPA Cell Line Gene Expression Profiles -1.0 -0.970747 Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.81912 MAATS1 Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.834118 KIAA2026 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.06897 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCIH2228 CCLE Cell Line Gene CNV Profiles -1.0 -2.48862 Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12104 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26049 GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0233 GTEX-SN8G-0126-SM-32PLI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36288 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.3124 ATP5O Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13845 IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.77832 NCIH2452 CCLE Cell Line Gene Expression Profiles -1.0 -2.00224 GTEX-QESD-1426-SM-2S1R9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25769 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.53198 IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.85601 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.22581 GTEX-W5WG-0008-SM-4KL25 GTEx Tissue Sample Gene Expression Profiles 1.0 0.829026 obesity GWASdb SNP-Phenotype Associations 1.0 1.32793 GTEX-T2YK-0005-SM-32QOV GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 GTEX-S32W-0126-SM-4AD61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17398 GTEX-S4Z8-1826-SM-3K2BH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.985523 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.59094 Prostate adenocarcinoma_PRAD_TCGA-J4-8198-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-0626-SM-4DM6H GTEx Tissue Sample Gene Expression Profiles 1.0 0.906211 GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64954 bonemarrow_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.89532 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66373 GTEX-WVLH-0011-R10A-SM-3MJFM GTEx Tissue Sample Gene Expression Profiles 1.0 1.07392 Perturb_13949_KD_CDK4/CDK6_SRP258989 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.04047 KIAA0319 Pathway Commons Protein-Protein Interactions 1.0 null RMGI CCLE Cell Line Gene Expression Profiles 1.0 1.55147 Perturb_3596_KO_DELE1_SRP218218 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.93047 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arthritis GWASdb SNP-Disease Associations 1.0 0.467454 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.2768 J82 CCLE Cell Line Gene CNV Profiles -1.0 -1.5026 GTEX-QDVJ-0226-SM-2I5FV GTEx Tissue Sample Gene Expression Profiles 1.0 0.851153 PDHA2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12107_KD_CCND1_SRP244245 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.35205 lipid metabolism disorder GWASdb SNP-Disease Associations 1.0 1.48714 Perturb_8285_KD_DDX27_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.09748 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HV-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded vesicle GO Cellular Component Annotations 2015 1.0 null GTEX-WYVS-0006-SM-3NMA7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22363 Sarcoma_SARC_TCGA-X6-A8C7-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV6 Pathway Commons Protein-Protein Interactions 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.072767 GP2D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.833828 skeletalmuscle_a HPA Tissue Sample Gene Expression Profiles -1.0 -1.53964 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35409 testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 2.02387 LXF289 CCLE Cell Line Gene CNV Profiles -1.0 -1.51737 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48503 GTEX-POYW-0826-SM-2XCEM GTEx Tissue Sample Gene Expression Profiles 1.0 0.870619 Perturb_11373_KD_USP22_SRP229365 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.21568 GTEX-X88G-0008-SM-47JWN GTEx Tissue Sample Gene Expression Profiles 1.0 0.885095 testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.20265 JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 abnormality of the urinary system GWASdb SNP-Phenotype Associations 1.0 1.57945 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68308 MKN1 CCLE Cell Line Gene CNV Profiles -1.0 -1.66889 HCC1569 CCLE Cell Line Gene CNV Profiles 1.0 1.45442 COLO 800 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.26028 Perturb_9855_KD_MSI2_SRP096137 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.65328 PSMC1 Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hypertension GWASdb SNP-Disease Associations 1.0 1.48714 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.05544 GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09873 Perturb_5711_KO_Dgcr8_SRP043436 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.51481 Perturb_8096_KD_SRSF5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.58961 GTEX-QVUS-0011-R10A-SM-3GIK3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05027 DENND3 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_5426_KD_ARID1A_SRP356912 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.72254 primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.403 Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6939_KD_EP300_SRP068733 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.78418 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -1.61973 G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.63947 Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.04363 Perturb_15587_KD_EP300_SRP355992 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.83288 Perturb_5646_KD_LOXHD1_SRP298159 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.48973 Perturb_702_KD_SETDB1_SRP116954 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.01767 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.37833 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.66274 Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02561 TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.75613 GTEX-UJHI-1526-SM-3DB99 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09766 Perturb_2548_KO_MLL3_SRP163132 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.4183 H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_14890_KO_H15_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.48098 Aspartate Aminotransferase Measurement DisGeNET Gene-Phenotype Associations 1.0 null NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26049 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23227 RFX7 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.50257 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26239 Perturb_15401_KD_MELK_SRP098926 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.69034 HDAC6 ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GR-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8227_KD_HDGF_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.12568 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.073353 H3K79me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.854174 VMRCLCD CCLE Cell Line Gene CNV Profiles 1.0 1.58222 GTEX-QCQG-0526-SM-48U2A GTEx Tissue Sample Gene Expression Profiles 1.0 1.05264 mediodorsal nucleus of thalamus_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38303 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19746 Perturb_5647_KD_JQ1_SRP142503 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.52138 NPTX2 Pathway Commons Protein-Protein Interactions 1.0 null RAD50 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8145_KD_AKAP8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.01291 SC-33172 (GADD45B) NURSA Protein Complexes 1.0 null Perturb_3627_KO_HDAC2_SRP355605 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.0 Perturb_9999_KD_BOP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.24955 hippocampus (hippocampal formation)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40779 RBM10 Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0842 Perturb_7812_KD_RRP40_SRP091999 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.699 H3K9me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.853721 Perturb_3646_KO_HDAC1_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.15653 HCC1806 COSMIC Cell Line Gene CNV Profiles 1.0 2.76305 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X261-3226-SM-3NMC3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23577 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QZ-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Creatine Kinase Measurement DisGeNET Gene-Phenotype Associations 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.90542 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B6-01A-21R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-2226-SM-4DXUR GTEx Tissue Sample Gene Expression Profiles 1.0 1.18531 ventromedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01503 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.064743 GTEX-WH7G-0008-SM-4LVNM GTEx Tissue Sample Gene Expression Profiles 1.0 0.844349 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929174 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.56593 Perturb_8288_KD_FKBP4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.69981 GTEX-NFK9-0626-SM-2HMIV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.901486 blood coagulation disease GWASdb SNP-Disease Associations 1.0 0.35337 NCIH1092 CCLE Cell Line Gene Expression Profiles -1.0 -2.43276 extracellular vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 overnutrition GWASdb SNP-Disease Associations 1.0 0.779178 GTEX-O5YT-1626-SM-32PK6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67717 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.855347 GTEX-S4Z8-0126-SM-4GICC GTEx Tissue Sample Gene Expression Profiles 1.0 1.15071 Perturb_8148_KD_NKRF_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.97179 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08469 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.39823 CTBP1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7821_Mut_BAZ1A_SRP100570 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.31129 H3K36me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16995 orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05443 TRRAP Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6785_KD_USP42_ERP121305 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.68518 GTEX-X8HC-0126-SM-4E3JW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02032 CDC26 Pathway Commons Protein-Protein Interactions 1.0 null cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.286218 GTEX-OHPL-1626-SM-2HMIR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05745 Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.991707 Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TKQ2-0826-SM-33HB6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_163_KD_RAC1_SRP387923 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.83752 hel HPA Cell Line Gene Expression Profiles 1.0 1.28221 BICR18 CCLE Cell Line Gene Expression Profiles 1.0 1.57183 Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VJYA-1226-SM-3GIJ6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0233 GTEX-U3ZN-0002-SM-3NMDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.04682 MAP1A Pathway Commons Protein-Protein Interactions 1.0 null ELMSAN1 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-1229 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 BIKE Kinase Library Serine Threonine Kinome Atlas 1.0 null GTEX-XGQ4-0426-SM-4AT4I GTEx Tissue Sample Gene Expression Profiles 1.0 0.909157 NCIH211 CCLE Cell Line Gene CNV Profiles 1.0 1.60927 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.09538 Perturb_14759_KD_LATS1/LATS2_SRP345234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.2702 MAP3K1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QLQW-0226-SM-447BJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.20176 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.974943 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.11256 atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.362487 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.26104 GTEX-NPJ8-0526-SM-3MJHN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.921532 GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.63897 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.846961 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.50487 GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.996545 GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36861 CKAP4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 heart GTEx Tissue Gene Expression Profiles -1.0 -0.900664 GTEX-TSE9-0126-SM-3DB83 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15995 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4894 ACTC1 Pathway Commons Protein-Protein Interactions 1.0 null OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.989433 CROCC Pathway Commons Protein-Protein Interactions 1.0 null Prucalopride DeepCoverMOA Drug Mechanisms of Action -1.0 -0.58 MAGI1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WZTO-0826-SM-3NM8Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47907 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.32948 GEMIN5 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 SK-N-SH Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02806 Perturb_10002_KD_FTO_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.63576 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7413-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC366 CCLE Cell Line Gene Expression Profiles -1.0 -1.49157 ATP5C1 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.14273 GTEX-QVJO-1826-SM-447C9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.911433 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.91364 FZR1 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.860848 LIMS1 Pathway Commons Protein-Protein Interactions 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_8190_KD_HNRNPU_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.241 Perturb_72_KD_DNTM3B_SRP315598 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.56244 GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45391 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.87376 SP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02676 KG1C CCLE Cell Line Gene Expression Profiles -1.0 -1.80727 Perturb_14888_KO_H14_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.734 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null thyroid_5b HPA Tissue Sample Gene Expression Profiles 1.0 0.88024 GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29186 Perturb_10194_KD_TAF1_SRP149373 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_8301_KD_ETF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.9203 GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58487 intracellular organelle GO Cellular Component Annotations 2015 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null NAIP Pathway Commons Protein-Protein Interactions 1.0 null cognitive disorder GWASdb SNP-Disease Associations 1.0 0.110588 BL3283 (C7orf27) NURSA Protein Complexes 1.0 null Perturb_8055_KD_IGF2BP3_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.7274 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.917637 GTEX-OHPL-1326-SM-3MJGG GTEx Tissue Sample Gene Expression Profiles 1.0 0.99764 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.944789 XEN445 DeepCoverMOA Drug Mechanisms of Action -1.0 -0.31 Perturb_9933_KD_AKAP8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.60265 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9913_KD_HNRNPK_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.45235 KIF20B Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_699_KO_INTS6_SRP299234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.14784 cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.602429 Prostate adenocarcinoma_PRAD_TCGA-J4-A83I-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33051 CBFB Pathway Commons Protein-Protein Interactions 1.0 null HIST1H2AB Pathway Commons Protein-Protein Interactions 1.0 null STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_15465_OE_ETV4_SRP402451 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.7981 liver GTEx Tissue Gene Expression Profiles 1.0 0.917497 gout GWASdb SNP-Disease Associations 1.0 1.70555 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PVOW-2526-SM-2XCF7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.966858 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H6-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.32831 H3K9me3_U2OS_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.49269 primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.885329 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.358 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.76179 GTEX-RM2N-0526-SM-2TF4N GTEx Tissue Sample Gene Expression Profiles 1.0 0.85582 Perturb_9987_KD_TARDBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.97983 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4181 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.6446 UBA52 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8472_Mut|KD_IDH1_SRP099826 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.4307 GTEX-TMZS-0001-SM-3P61Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.872666 Perturb_9968_KD_UPF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.27363 GTEX-XPVG-2626-SM-4B669 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33649 Perturb_7372_KD_UPF1_ERP012939 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.12393 GTEX-S4P3-0926-SM-4AD54 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37203 Perturb_4762_KO_DLG2_SRP315088 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-WFG8-1326-SM-4LVN3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.948234 GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32614 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of body weight GWASdb SNP-Phenotype Associations 1.0 0.416272 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.71764 Perturb_3666_KO_FASTKD_SRP277516 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.21169 AAK1 Kinase Library Serine Threonine Kinome Atlas 1.0 null SDHA Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1467 SDF4 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7317_Mut_RNPS1_ERP130711 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.26955 Perturb_14889_KO_H14_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.96002 GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 0.835153 coronary artery disease GWASdb SNP-Disease Associations 1.0 1.41484 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.17345 Perturb_3586_KD_KHSRP_SRP250831 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.47802 Perturb_15978_KO_Tsga8_SRP254760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.33552 GTEX-TKQ1-1426-SM-4GICK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01872 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.75603 Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9888_KD_ESF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.44957 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.907743 GTEX-U412-0226-SM-3NMC8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62527 GTEX-S32W-1226-SM-4AD67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33493 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.72814 GTEX-T6MN-2626-SM-32PMQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.874288 KCNG3 Pathway Commons Protein-Protein Interactions 1.0 null CYP2U1 Pathway Commons Protein-Protein Interactions 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.45399 GTEX-WRHU-0226-SM-3MJFV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.849926 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DT-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12337_KD_TFEB_SRP226507 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.33892 GTEX-OIZI-0726-SM-2XCEI GTEx Tissue Sample Gene Expression Profiles 1.0 0.920617 DPM1 Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.839182 GTEX-POYW-1326-SM-48TCG GTEx Tissue Sample Gene Expression Profiles 1.0 1.25732 GTEX-TML8-1226-SM-32QON GTEx Tissue Sample Gene Expression Profiles 1.0 0.852653 USP36 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_14281_KD_XRN1_ERP131052 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.95663 diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.329719 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SE5C-1226-SM-4BRWV GTEx Tissue Sample Gene Expression Profiles 1.0 0.87712 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61516 Perturb_7535_KD_HNRNPL_SRP264981 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.52081 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.33324 CSMD2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X5EB-0004-SM-46MWA GTEx Tissue Sample Gene Expression Profiles 1.0 0.882902 Perturb_4911_KD_ATF7IP_SRP156289 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.96483 GTEX-XQ8I-0926-SM-4BOOF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50556 GTEX-TSE9-0226-SM-3DB84 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881685 Perturb_14068_KD_ALKBH5_SRP247667 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.66599 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02473 H4 CCLE Cell Line Gene CNV Profiles -1.0 -1.92686 Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.882692 SW1573 CCLE Cell Line Gene Expression Profiles -1.0 -1.51674 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.830306 GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.388 GTEX-RM2N-0126-SM-48FDD GTEx Tissue Sample Gene Expression Profiles 1.0 0.829057 XKRX Pathway Commons Protein-Protein Interactions 1.0 null PD 123319 DeepCoverMOA Drug Mechanisms of Action -1.0 -0.23 H3K9me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-1226-SM-3NMA5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44804 PSMD2 Pathway Commons Protein-Protein Interactions 1.0 null KARPAS-1106P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20345 ARG1 Pathway Commons Protein-Protein Interactions 1.0 null OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02857 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Y-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone disease GWASdb SNP-Disease Associations 1.0 0.295376 CTR9 Pathway Commons Protein-Protein Interactions 1.0 null PRRC2A Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8097_KD_SUCLG1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.78356 G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3262 SGOL2 Pathway Commons Protein-Protein Interactions 1.0 null PCBP2 Pathway Commons Protein-Protein Interactions 1.0 null medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.41303 behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.105162 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00718 RALGAPA1 Pathway Commons Protein-Protein Interactions 1.0 null HIRA Pathway Commons Protein-Protein Interactions 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null Perturb_9821_KD_MYB_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.06667 GTEX-P4PP-2426-SM-3P61L GTEx Tissue Sample Gene Expression Profiles 1.0 1.37647 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null HCA-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.35907 SQRDL Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15634_KO_AHCY_SRP351305 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.01501 IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.33389 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7XN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9963_KD_MTPAP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.37847 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38003 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A6UC-01A-21R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.67348 Perturb_10190_KD_AES_SRP073721 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.74756 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7541_KO_NSUN6_SRP273753 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.19152 MAP3K5 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8174_KD_PABPC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.2101 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910908 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 2.09429 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 CALD1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_3656_KO_MTHFD1_SRP120974 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 organelle GO Cellular Component Annotations 2015 1.0 null AHNAK Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10031_KD_MSI2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.713 MAST4 Pathway Commons Protein-Protein Interactions 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4QT-0126-SM-2I3FL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00955 OPHN1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WHSB-1826-SM-3TW8M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03293 DHX58 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4790-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23329 GSK3B Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6879_KD_LINC00857_SRP371132 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.88982 inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.06079 DDX47 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_11523_KD_NR0B1_SRP092641 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.80709 YH13 CCLE Cell Line Gene Expression Profiles -1.0 -1.84513 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.51606 Perturb_12725_KO_MITF_SRP255094 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.02667 Perturb_9695_KO_GPNMB_SRP382180 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.96918 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14906 DMS454 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 GTEX-SE5C-0626-SM-2XCDV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.840319 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2877 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_8136_KD_G3BP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.27267 atherosclerosis GWASdb SNP-Disease Associations 1.0 1.32233 BRCA1 JASPAR Predicted Transcription Factor Targets 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14570_KO_RORC_SRP185849 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.32698 Brain Lower Grade Glioma_LGG_TCGA-E1-5318-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0526-SM-4B662 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07647 CNOT4 Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.893254 Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8221_KD_ACO1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.64599 mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.78922 JHOM2B CCLE Cell Line Gene Expression Profiles -1.0 -2.63199 Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null extracellular region part GO Cellular Component Annotations 2015 1.0 null GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.00289 NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.71665 extracellular region part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 myopathy GWASdb SNP-Disease Associations 1.0 1.32233 MATN4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 TBL2 Pathway Commons Protein-Protein Interactions 1.0 null Gout DisGeNET Gene-Disease Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-2A-A8VT-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QV44-0826-SM-2S1RG GTEx Tissue Sample Gene Expression Profiles 1.0 0.844685 Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ISTMES1 CCLE Cell Line Gene CNV Profiles -1.0 -1.93509 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26239 Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4665 RPL26L1 Pathway Commons Protein-Protein Interactions 1.0 null disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.127844 GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40459 OTUD4 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6765_KD_PAF1_SRP103746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.3665 Perturb_8245_KD_TIA1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.44671 arteriosclerotic cardiovascular disease GWASdb SNP-Disease Associations 1.0 0.587571 GTEX-XUZC-0226-SM-4BOO7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02232 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-W5WG-1126-SM-4LMK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.39596 Perturb_13905_KD_DAZAP1_SRP102807 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.8729 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.30112 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 3.06166 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20224 Perturb_10007_KD_HNRNPA1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.63366 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.943458 Perturb_232_KD_HIF1A_SRP100624 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.31812 GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25384 Perturb_8075_KD_AATF_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.32092 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0842 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15518 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.978819 IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990748 H3K9me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_17619_KO_MLLT6_SRP245883 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3456-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DNAJB12 Pathway Commons Protein-Protein Interactions 1.0 null SYNE1 Pathway Commons Protein-Protein Interactions 1.0 null BICR6 CCLE Cell Line Gene Expression Profiles 1.0 2.17977 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 NB1 COSMIC Cell Line Gene CNV Profiles 1.0 2.76305 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52114 reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.50466 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.79562 Lung adenocarcinoma_LUAD_TCGA-05-4384-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02754 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRDM1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-WFON-0626-SM-4LVLX GTEx Tissue Sample Gene Expression Profiles 1.0 0.829012 HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08358 Perturb_7662_KD_CTCF_SRP072272 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.54215 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 2.49491 PDS5B Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-650 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 BAHCC1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8233_KD_RBM15_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.73676 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14906 Perturb_13704_KD_SMARCA2_SRP247495 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.79144 HCC202 CCLE Cell Line Gene CNV Profiles 1.0 1.35088 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4EP-0126-SM-3P5YV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.884326 H3K36me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_8269_KD_METAP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.71887 primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.898854 NOMO2 Pathway Commons Protein-Protein Interactions 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-XUYS-0008-SM-47JYZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.923351 ZFHX3 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Perturb_15477_OE_MYC_SRP218384 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.69868 STAT3 ChEA Transcription Factor Targets 1.0 null CEP55 Pathway Commons Protein-Protein Interactions 1.0 null LOUCY CCLE Cell Line Gene Expression Profiles -1.0 -1.80475 ZNF541 Pathway Commons Protein-Protein Interactions 1.0 null carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.69594 GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48712 HS 255.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.12015 TXN Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5633-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.78981 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59332 KHM1B CCLE Cell Line Gene Expression Profiles 1.0 1.59974 GTEX-S4P3-0226-SM-3K2BD GTEx Tissue Sample Gene Expression Profiles 1.0 0.9968 DIP2B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-V1D1-0226-SM-4JBHG GTEx Tissue Sample Gene Expression Profiles 1.0 0.829364 bonemarrow_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.08601 GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.911325 Perturb_7639_KD_PCF11_SRP169609 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.21629 EP400 Pathway Commons Protein-Protein Interactions 1.0 null MCTP2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S95S-1226-SM-4GICG GTEx Tissue Sample Gene Expression Profiles 1.0 1.32423 OAW42 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.3511 FRMD6 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.916461 PPA2 Pathway Commons Protein-Protein Interactions 1.0 null NCIH1623 CCLE Cell Line Gene CNV Profiles 1.0 1.69448 GATA2 ChEA Transcription Factor Targets 1.0 null AIFM2 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02473 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.981496 Perturb_12338_KD_TFEB_SRP226507 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.05181 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.48305 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.32375 OBSCN Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7431_KO|KD_RBFOX2|RBFOX1_SRP068106 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.75471 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.9852 stomach_3a HPA Tissue Sample Gene Expression Profiles 1.0 0.925143 ventrolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.31626 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15108 BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46441 NCI-H1623 COSMIC Cell Line Gene CNV Profiles 1.0 2.76305 GTEX-Q2AI-0226-SM-48U1D GTEx Tissue Sample Gene Expression Profiles 1.0 1.31124 Perturb_2524_KD_SYF2_SRP185438 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.29873 GTEX-X4XY-0826-SM-4E3JM GTEx Tissue Sample Gene Expression Profiles 1.0 0.920571 CLEC11A Pathway Commons Protein-Protein Interactions 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.03292 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRABD2A Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3Z-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87D-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QDVJ-1126-SM-48U1U GTEx Tissue Sample Gene Expression Profiles 1.0 0.972946 STAU1_DELETION_GDS3370_56_human_HeLa GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TDG Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924172 GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.146305 TUBB6 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.81248 H3K9me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QEL4-0726-SM-3GIJ5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.966291 OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.94827 Perturb_8275_KD_SF3A3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.36414 GTEX-QDVN-0426-SM-48TZ6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12152 ACACA Pathway Commons Protein-Protein Interactions 1.0 null Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44269 HS888T CCLE Cell Line Gene Expression Profiles -1.0 -1.54045 Perturb_17639_OE_WWTR1_SRP298391 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.00281 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -1.66588 NCI-H2347 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.860926 Brain Lower Grade Glioma_LGG_TCGA-DU-8164-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 2.64677 RAB11FIP5 Pathway Commons Protein-Protein Interactions 1.0 null efo21 HPA Cell Line Gene Expression Profiles 1.0 0.979132 SIPA1L3 Pathway Commons Protein-Protein Interactions 1.0 null BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01249 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.846286 P12ICHIKAWA CCLE Cell Line Gene Expression Profiles 1.0 1.51581 disease GWASdb SNP-Disease Associations 1.0 0.123321 GTEX-S7SF-0001-SM-3K2BE GTEx Tissue Sample Gene Expression Profiles 1.0 1.22318 Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KALS1 CCLE Cell Line Gene CNV Profiles -1.0 -1.3948 AGPAT1 Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4396-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.883819 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.939804 Perturb_9938_KD_DKC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.09014 Perturb_4745_KD_ADAR1/ADAR2_SRP050149 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.76463 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.92562 GTEX-OHPK-1326-SM-3MJGN GTEx Tissue Sample Gene Expression Profiles 1.0 1.19334 GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Perturb_2591_OE_YBX1_SRP100638 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.93984 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.905044 Perturb_17803_KO_ZNF675_SRP305529 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.56733 Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCFC2 Pathway Commons Protein-Protein Interactions 1.0 null DACT1 Pathway Commons Protein-Protein Interactions 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 0.965756 BL2157 (USP34) NURSA Protein Complexes 1.0 null BL1571 (ITCH) NURSA Protein Complexes 1.0 null GTEX-P4QS-1326-SM-3NMCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.08809 GTEX-XYKS-1726-SM-4E3IO GTEx Tissue Sample Gene Expression Profiles 1.0 0.910876 GTEX-UPJH-0006-SM-3GACW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.54066 PLA2G4A Pathway Commons Protein-Protein Interactions 1.0 null Perturb_734_KD_SETD1A_SRP293637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.60941 GTEX-SUCS-0526-SM-4DM56 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18234 posteroventral (inferior) parietal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07122 Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EHHADH Pathway Commons Protein-Protein Interactions 1.0 null bone inflammation disease GWASdb SNP-Disease Associations 1.0 0.441728 HIST1H1A Pathway Commons Protein-Protein Interactions 1.0 null H3K9me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LGALS1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8144_KD_PABPC4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.37155 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 2.07604 GTEX-OIZH-1626-SM-2HMKI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13485 GTEX-QMR6-0008-SM-447AV GTEx Tissue Sample Gene Expression Profiles 1.0 0.866949 amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30656 MHHES1 CCLE Cell Line Gene Expression Profiles -1.0 -1.50094 posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.877354 striatum_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.896647 BC3C CCLE Cell Line Gene Expression Profiles -1.0 -1.6654 CHAGOK1 CCLE Cell Line Gene Expression Profiles 1.0 1.85737 CLSTN1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15866_KD_BMI1_ERP013870 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.11689 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00005 Perturb_15857_KD_KDM3A_SRP248023 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.08859 FASTKD1 Pathway Commons Protein-Protein Interactions 1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.851388 GTEX-T6MN-0002-SM-3NMAH GTEx Tissue Sample Gene Expression Profiles 1.0 0.926074 MRPL14 Pathway Commons Protein-Protein Interactions 1.0 null IZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08345 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.892862 GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 GTEX-VUSG-2526-SM-4KL1V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20725 GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35626 DDX24 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8507-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.33256 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.69806 Perturb_8473_Mut|KD_IDH1_SRP099826 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.70759 MYO1D Pathway Commons Protein-Protein Interactions 1.0 null diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.490495 Brain Lower Grade Glioma_LGG_TCGA-HT-7677-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980766 FADU CCLE Cell Line Gene CNV Profiles -1.0 -1.55787 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15412 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.0111 GTEX-S341-1826-SM-3K2AB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36642 Waist Circumference - Triglycerides (WC-TG) GWAS Catalog SNP-Phenotype Associations 1.0 0.499091 Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTBP1 Pathway Commons Protein-Protein Interactions 1.0 null RBM39 Pathway Commons Protein-Protein Interactions 1.0 null SW1116 CCLE Cell Line Gene Expression Profiles 1.0 1.7964 MZ in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13257 thyroid_5a HPA Tissue Sample Gene Expression Profiles 1.0 1.02515 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26239 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-RTLS-1326-SM-46MUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.34057 primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.69577 gallbladder HPA Tissue Protein Expression Profiles 1.0 0.733372 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.843635 Perturb_2525_KD_SYF2_SRP185438 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.97365 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.64937 hsa-miR-4436b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 H3K9me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9918_KD_MAGOH_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.10114 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.31962 TPP1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_11467_KD_SRSF1_SRP290964 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRK-0008-SM-3NB28 GTEx Tissue Sample Gene Expression Profiles 1.0 0.891343 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04076 Perturb_6480_KD_SNRPB_ERP011528 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-X8HC-1626-SM-46MWE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08972 hsa-miR-4443 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95637 Serum Albumin Measurement DisGeNET Gene-Phenotype Associations 1.0 null striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.872997 Perturb_6441_KO_MRTFA_SRP134183 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.62931 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 2.15635 GTEX-U412-0008-SM-4DXTE GTEx Tissue Sample Gene Expression Profiles 1.0 0.887263 Sarcoma_SARC_TCGA-IE-A4EK-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SACS Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XBEW-1326-SM-4AT63 GTEx Tissue Sample Gene Expression Profiles 1.0 0.985342 Perturb_2779_OE_ACF7_SRP109301 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.40501 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF354B Pathway Commons Protein-Protein Interactions 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.49747 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.01878 testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.47215 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LOVO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.990351 HCV_8week+IFN-a_None_GSE37715 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.92844 GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.995571 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.915553 triglycerides GAD Gene-Disease Associations 1.0 null disease of metabolism GWASdb SNP-Disease Associations 1.0 0.429753 u26684 HPA Cell Line Gene Expression Profiles -1.0 -1.15683 RUNX1 Pathway Commons Protein-Protein Interactions 1.0 null MCM4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WFJO-0226-SM-3GIKW GTEx Tissue Sample Gene Expression Profiles 1.0 1.17433 hsa-miR-324-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 HEP3B217 CCLE Cell Line Gene Expression Profiles 1.0 3.40796 plasma membrane LOCATE Curated Protein Localization Annotations 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.25604 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWO3-0011-R2A-SM-2S1OX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 PML Pathway Commons Protein-Protein Interactions 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.867494 MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23565 TEX2 Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19679 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.67837 Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.865636 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53534 Lung adenocarcinoma_LUAD_TCGA-64-5774-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Perturb_3848_KD_lncRNAAK096729_SRP192850 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.7835 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47803 ZNF740 Pathway Commons Protein-Protein Interactions 1.0 null HSPB1 Pathway Commons Protein-Protein Interactions 1.0 null TRAK1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-Q2AH-0726-SM-2I3EA GTEx Tissue Sample Gene Expression Profiles 1.0 0.9619 GTEX-XMD3-0006-SM-4AT5X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19309 NCIH1395 CCLE Cell Line Gene CNV Profiles 1.0 1.35521 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.54175 Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8085_KD_DAZAP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.84269 Perturb_8090_KD_HNRNPL_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.7583 GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10422 NFIL3 Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.850619 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.936626 POLR3A Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OXRN-0526-SM-2I5EN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18611 Perturb_8086_KD_EIF4G1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.03641 Perturb_444_KD_AKR1B1_SRP121474 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.58338 Perturb_7633_KD_ENL_SRP078067 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.96185 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.876692 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10443_KO_miR29a_SRP075398 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.83556 Perturb_9093_KD_SMARCA4_SRP293297 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.7342 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6516-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8237_KD_QKI_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.7442 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.92318 OlfactoryBulb BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.85401 NCIH1963 CCLE Cell Line Gene Expression Profiles -1.0 -1.55883 Perturb_8127_KD_ASCC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.81025 GTF3C4 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_10666_OE_HSPB2_SRP288471 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.42415 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44302 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.89407 Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 23132/87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00758 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.910024 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01987 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19151 GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47956 Perturb_13753_KD_EP300_SRP233218 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.25546 Perturb_17691_KD_MDMX_SRP393452 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.59467 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02117 GTEX-X4XX-0126-SM-3NMC2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22319 TRPM1 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70D-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8280_KD_DDX5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.38167 UterusCorpus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.21488 hsa-miR-1254 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GTEX-RN64-1826-SM-48FDV GTEx Tissue Sample Gene Expression Profiles 1.0 1.47155 GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.864617 placenta HPA Tissue Protein Expression Profiles 1.0 1.3706 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12405 MAGEB10 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5525-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_477_OE_ACE2_SRP278541 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.78777 IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 2.42656 20174566-TableS1 GeneSigDB Published Gene Signatures 1.0 null MFHAS1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XBED-2626-SM-4E3J5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.997864 BL533 (CCAR1) NURSA Protein Complexes 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95637 GTEX-TKQ2-0226-SM-4DM6V GTEx Tissue Sample Gene Expression Profiles 1.0 0.830527 lateral nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.853008 Perturb_15158_KD_MTOR_SRP192607 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.77666 FRMPD4 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9964_KD_NSUN2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.5597 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08346 GTEX-XBEC-1326-SM-4AT69 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Perturb_7830_KD_PREP1_SRP113380 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.11328 GTEX-SUCS-0002-SM-3NMAJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.01213 Perturb_7489_KD_SIN3A_SRP173465 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.57951 GTEX-S32W-2126-SM-2XCB1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0057 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.914344 GTEX-SNOS-1526-SM-32PLW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52007 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61977 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZM-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPL-2426-SM-48TDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.3457 immune system disease GWASdb SNP-Disease Associations 1.0 0.109591 Perturb_17543_KD_MLK4_SRP320486 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.79505 GTEX-UJMC-0226-SM-4IHLH GTEx Tissue Sample Gene Expression Profiles 1.0 0.859718 GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.52318 GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Perturb_15022_KD_RelA_SRP078053 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.06015 Perturb_7387_KO_UPF3B_ERP130413 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.30938 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26461 Perturb_8186_KD_DNAJC21_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.26031 SH3RF1 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IL16 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PWN1-1526-SM-48TDA GTEx Tissue Sample Gene Expression Profiles 1.0 0.993785 Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCIMY5 CCLE Cell Line Gene CNV Profiles 1.0 1.35621 hsa-miR-671-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-X4EP-0011-R2B-SM-3P625 GTEx Tissue Sample Gene Expression Profiles 1.0 0.956346 type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 1.68392 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13682 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.3582 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.74834 Perturb_8354_KD_PtenTraf3_SRP337419 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.97717 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 GTEX-OIZI-0226-SM-2XCEE GTEx Tissue Sample Gene Expression Profiles 1.0 1.13225 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XG-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blood GTEx Tissue Gene Expression Profiles -1.0 -0.95771 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.11355 dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.45039 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19962 BL5105 (BRF1) NURSA Protein Complexes 1.0 null GTEX-P4PQ-2626-SM-33HC9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05946 Perturb_7933_KD_Spt6_SRP132004 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.4638 stratum pyramidale of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16809 Perturb_10004_KD_KRR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.05073 abnormality of lipid metabolism GWASdb SNP-Phenotype Associations 1.0 1.23829 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein c deficiency GWASdb SNP-Disease Associations 1.0 1.55404 USP10 Pathway Commons Protein-Protein Interactions 1.0 null SNU213 CCLE Cell Line Gene Expression Profiles -1.0 -2.74924 GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21455 coronary artery disease GWASdb SNP-Phenotype Associations 1.0 1.15867 GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.987901 Perturb_563_KD_MYCN_SRP158473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.07662 primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.28005 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.854951 GTEX-T8EM-1226-SM-4DM5J GTEx Tissue Sample Gene Expression Profiles 1.0 0.981693 abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.141053 A-CA-04-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.8899 skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles -1.0 -1.30171 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62796 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.45846 Perturb_8192_KD_PARN_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.39131 male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-WHSE-0126-SM-3NMBT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.904428 posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42268 GTEX-U3ZM-0008-SM-4DXTQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.894173 Perturb_14359_KD_BUB3_SRP057074 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.03477 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06696 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKL1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15559_KO_SLFN11_SRP327912 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.16905 primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.950663 Perturb_8236_KD_PTBP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.57388 IMMT Pathway Commons Protein-Protein Interactions 1.0 null Perturb_14320_KD_CD95L_SRP111532 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.42995 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 1.55044 FOXC2 Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13949 Perturb_10008_KD_HNRNPU_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 RRM1 Pathway Commons Protein-Protein Interactions 1.0 null SNX19 Pathway Commons Protein-Protein Interactions 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13566 Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.59081 PHF20 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9696_KO_GPNMB_SRP382180 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.43049 GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06972 Perturb_9370_KD_ARID1A89_SRP385862 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.30976 disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.602429 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33521 GTEX-X62O-0005-SM-46MV1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12592 GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11172 MIB1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9130_KD_PHGDH_ERP020769 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.45394 GTEX-Q2AH-0008-SM-48U2J GTEx Tissue Sample Gene Expression Profiles 1.0 0.829657 Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4341_OE_MYT1L_SRP271657 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.5052 LUZP1 Pathway Commons Protein-Protein Interactions 1.0 null outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05154 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12905_KD_MDC1_SRP313175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.59866 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13779 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PJ-01A-21R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8128_KD_CIRBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.30758 Perturb_15979_KO_Tsga8_SRP254760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.7798 Adrenocortical carcinoma_ACC_TCGA-PK-A5HA-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.41227 Perturb_2506_KD_NXF1_SRP226431 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.51416 Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HL-60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.859601 MUC3A Pathway Commons Protein-Protein Interactions 1.0 null muscle tissue disease GWASdb SNP-Disease Associations 1.0 0.321937 UBA1 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-5125-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7770_KO_SatIII_DRP005513 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.61385 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15336 GTEX-WFG8-0426-SM-3GILD GTEx Tissue Sample Gene Expression Profiles 1.0 0.861315 ACACB Pathway Commons Protein-Protein Interactions 1.0 null ABC1 CCLE Cell Line Gene CNV Profiles 1.0 1.78168 HCC1195 CCLE Cell Line Gene Expression Profiles 1.0 1.61144 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICR56 CCLE Cell Line Gene CNV Profiles -1.0 -2.3767 SOX11_DEPLETION_GDS4801_326_human_Z138 mantle cell lymphoma (MCL) cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF703 Pathway Commons Protein-Protein Interactions 1.0 null abnormalities of the peripheral arteries GWASdb SNP-Phenotype Associations 1.0 0.31572 Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5752-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8138_KD_IGF2BP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.85563 GTEX-RWS6-0826-SM-47JXF GTEx Tissue Sample Gene Expression Profiles 1.0 0.832404 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.44656 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.67275 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27958 GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38913 GTEX-S341-0726-SM-4AD5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.00826 CACNA1G Pathway Commons Protein-Protein Interactions 1.0 null H3K9me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4UY-0526-SM-3K2AN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877516 GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Lung adenocarcinoma_LUAD_TCGA-44-2662-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.859762 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.67009 SUCLG1 Pathway Commons Protein-Protein Interactions 1.0 null LP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.67289 Perturb_12522_KD_MUC1_SRP381930 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.31594 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9867_Mut|KD_SRSF2_SRP368113 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.70728 GTEX-XUW1-0826-SM-4BOP6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03882 GTEX-QLQW-0626-SM-447A6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.89473 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14354_KD_TUT4/TUT7_SRP120600 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.96481 Perturb_257_KD_KLF6_SRP150445 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.06845 hsa-miR-4697-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 MAX Pathway Commons Protein-Protein Interactions 1.0 null Perturb_101_KD_LATS_SRP353750 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.19129 Perturb_16318_KD_SYNCRIP_SRP144940 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.42032 GTEX-VUSG-2626-SM-4KKZI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.851431 GTEX-S3XE-1326-SM-4AD4H GTEx Tissue Sample Gene Expression Profiles 1.0 0.833246 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-SNOS-0003-SM-3NMAO GTEx Tissue Sample Gene Expression Profiles 1.0 0.838323 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.921906 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 1.36253 GTEX-RNOR-1426-SM-48FDJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.46278 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.884033 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.337502 Perturb_7948_KD_SKIIP_SRP155347 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.21462 Perturb_8277_KD_UTP18_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.80795 Perturb_3594_KO_DELE1_SRP218218 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.28348 GTEX-XGQ4-0008-SM-4AT3Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.905235 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00235 PADI2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.63557 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.49906 Perturb_10357_KD_BRD4_SRP093774 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 HADHB Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7632-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDV3 Pathway Commons Protein-Protein Interactions 1.0 null SNU869 CCLE Cell Line Gene Expression Profiles 1.0 1.3617 GTEX-S95S-1326-SM-2XCDK GTEx Tissue Sample Gene Expression Profiles 1.0 0.930973 primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17277 GTEX-WFON-2326-SM-3LK7M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.892057 GTEX-U3ZM-1226-SM-3DB9G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.83232 Perturb_8184_KD_DHX30_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.80843 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.58363 Perturb_6291_KO_ZNF165_SRP390251 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.32354 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.6468 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24162 Perturb_9638_KO_CHCHD2_SRP212876 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.81571 8MGBA CCLE Cell Line Gene Expression Profiles -1.0 -2.12161 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.927711 hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1545 GTEX-U3ZH-1926-SM-4DXTR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.862392 thyroid gland HPA Tissue Gene Expression Profiles 1.0 1.37898 Perturb_7488_OE_RAMP2_SRP169097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.8051 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.28796 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.14271 MCF2L2 Pathway Commons Protein-Protein Interactions 1.0 null GATA2-19941826-K562-human ChEA Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21812 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.46882 Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19743 GTEX-OHPM-1626-SM-2HMK4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04864 KLM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.77115 Prostate adenocarcinoma_PRAD_TCGA-VP-A876-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7211_Mut_MED26_SRP164752 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.71532 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.850822 GTEX-SUCS-1626-SM-32PLS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.832628 GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05867 skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles -1.0 -1.21363 GTEX-QEG5-0006-SM-2I5FZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63149 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FERMT3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-UTHO-1826-SM-3GAFE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.833304 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3940_KD_IRGM_ERP122050 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.48467 Perturb_8137_KD_HNRNPK_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.4622 BGC823 CCLE Cell Line Gene CNV Profiles -1.0 -1.3626 GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35336 MKN45 CCLE Cell Line Gene CNV Profiles -1.0 -2.05118 nucleus GO Cellular Component Annotations 2015 1.0 null H3K27me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08365 Perturb_15213_KD_BRD4_SRP255722 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.09064 nucleus GO Cellular Component Annotations 2023 1.0 null Perturb_1048_KD_H19_SRP132802 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.61052 cell part LOCATE Curated Protein Localization Annotations 1.0 null RPP30 Pathway Commons Protein-Protein Interactions 1.0 null gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34483 artery disease GWASdb SNP-Disease Associations 1.0 0.426923 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.67606 H3K9me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 2.09515 NCOR1 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.860057 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42924 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SHE Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.59628 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 increased body weight GWASdb SNP-Phenotype Associations 1.0 1.32793 Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4775-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2703-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHAF1B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XOT4-0005-SM-4B64S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.95836 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.98322 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.833906 H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23119 GTEX-Q2AH-0126-SM-48U2B GTEx Tissue Sample Gene Expression Profiles 1.0 0.963097 COV504 CCLE Cell Line Gene CNV Profiles 1.0 1.50028 K562 CCLE Cell Line Gene Expression Profiles 1.0 1.61664 extracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-WRHU-1226-SM-4E3IJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3059 CDC42EP1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-T6MN-0526-SM-32PMS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2303 GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28771 SK-MEL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.950245 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RN-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABCA9 Pathway Commons Protein-Protein Interactions 1.0 null TNPO1 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1913 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO792 CCLE Cell Line Gene Expression Profiles 1.0 1.55802 GTEX-PWN1-0626-SM-48TDT GTEx Tissue Sample Gene Expression Profiles 1.0 0.828884 Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7339_KO_TIP60_SRP386875 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.23974 GTEX-OIZH-0126-SM-2HMIS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.899744 IL1B Pathway Commons Protein-Protein Interactions 1.0 null cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06447 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEC11C Pathway Commons Protein-Protein Interactions 1.0 null membrane-bounded vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-POMQ-1426-SM-3P61D GTEx Tissue Sample Gene Expression Profiles 1.0 0.962469 ABRA Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17034 abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.103231 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00364 Brain Lower Grade Glioma_LGG_TCGA-DU-7298-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LY 487379 DeepCoverMOA Drug Mechanisms of Action 1.0 0.35 GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844468 GTEX-WYVS-2326-SM-3NMAI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16352 Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09917 PPP2R3B Pathway Commons Protein-Protein Interactions 1.0 null PCM6 CCLE Cell Line Gene Expression Profiles -1.0 -1.76333 RPRD2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U8T8-0126-SM-3DB94 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44908 NCIH2141 CCLE Cell Line Gene CNV Profiles -1.0 -1.52045 GTEX-S4P3-1626-SM-3K2AZ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 BRWD1 Pathway Commons Protein-Protein Interactions 1.0 null GPR158 Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08156 GTEX-XOTO-0126-SM-4B66N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.843097 abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.229416 PFDN2 Pathway Commons Protein-Protein Interactions 1.0 null RPS2 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.060189 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869069 Sarcoma_SARC_TCGA-X2-A95T-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3655_KO_MTHFD1_SRP120974 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979547 PSMA3 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPC Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.996636 GTEX-SIU7-1126-SM-2XCDW GTEx Tissue Sample Gene Expression Profiles 1.0 0.871997 GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20421 HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00485 ALPK3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S3XE-2026-SM-3K2B5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33527 KANK2 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F6-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNRPF Pathway Commons Protein-Protein Interactions 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.74597 COCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.60341 Sarcoma_SARC_TCGA-MB-A8JL-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10015_KD_HNRNPC_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 SLC25A10 Pathway Commons Protein-Protein Interactions 1.0 null IZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.901367 SUCLG2 Pathway Commons Protein-Protein Interactions 1.0 null dorsal lateral geniculate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.842144 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YT-1326-SM-3MJGR GTEx Tissue Sample Gene Expression Profiles 1.0 1.16701 PLOD2 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SN8G-0008-SM-4DM4X GTEx Tissue Sample Gene Expression Profiles 1.0 0.825888 Perturb_8163_KD_SRSF3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.11473 primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.922516 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 SNU685 CCLE Cell Line Gene Expression Profiles -1.0 -2.29867 Perturb_13656_KO_TERT_SRP291201 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.67884 Perturb_11541_Mut_KRAS_SRP175175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.42078 RRP1B Pathway Commons Protein-Protein Interactions 1.0 null area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14032 GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 0.858982 abnormality of coagulation GWASdb SNP-Phenotype Associations 1.0 0.334855 GTEX-XUJ4-0726-SM-4BOOP GTEx Tissue Sample Gene Expression Profiles 1.0 0.92653 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4223 Brain Lower Grade Glioma_LGG_TCGA-TM-A84G-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8151_KD_SUGP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.5144 dorsolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08554 metabolic syndrome x GAD Gene-Disease Associations 1.0 null GTEX-WRHU-0006-SM-3MJF6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58832 HOXA10 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OHPK-2426-SM-3MJGH GTEx Tissue Sample Gene Expression Profiles 1.0 0.951172 HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.68758 Perturb_2543_KD_SNHG7_SRP179498 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.37816 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-539 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Perturb_7347_KD_ALKBH5_SRP070463 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.41181 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.884134 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49589 POP4 Pathway Commons Protein-Protein Interactions 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27958 GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBED-0126-SM-47JY7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.980022 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22549 GTEX-S7PM-0006-SM-3NM8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04869 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 2.20814 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39118 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.89528 H3K9me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-PWOO-0326-SM-48TDB GTEx Tissue Sample Gene Expression Profiles 1.0 0.966097 GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.962824 MED12L Pathway Commons Protein-Protein Interactions 1.0 null CZC-25146 DeepCoverMOA Drug Mechanisms of Action 1.0 0.28 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64639 GTEX-RU72-2226-SM-46MUE GTEx Tissue Sample Gene Expression Profiles 1.0 0.84823 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2667_KD_RBM39_SRP357624 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.53905 Perturb_8300_KD_AUH_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.94181 Perturb_9988_KD_CNOT7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.39008 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41788 metabolic syndrome x GWASdb SNP-Disease Associations 1.0 1.48714 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20527 UBTF Pathway Commons Protein-Protein Interactions 1.0 null Protein C Measurement DisGeNET Gene-Phenotype Associations 1.0 null MYO18A Pathway Commons Protein-Protein Interactions 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 cellular_component GO Cellular Component Annotations 2015 1.0 null GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.77538 posteroventral (inferior) parietal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30961 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01925 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3654_KO_METAP1_SRP116953 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.15872 GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.905697 TRAP1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_16814_OE_HNF1A/FOXA3/PROX1/SIRT1/PGC1A/AMPK_SRP167105 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.0376 ovary GTEx Tissue Gene Expression Profiles 1.0 0.940542 IZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17545 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.853341 JUN Pathway Commons Protein-Protein Interactions 1.0 null type ii diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.914846 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.978488 Perturb_13864_KD_KDM6B_SRP258989 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GTEX-R55E-0006-SM-2TC5G GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Perturb_8126_KD_AKAP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.81416 PLC/PRF/5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.17543 WIPF1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.94688 GTEX-SNOS-0226-SM-32PLR GTEx Tissue Sample Gene Expression Profiles 1.0 0.854975 Perturb_7292_KI_KMT2C_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.23747 GTEX-XK95-0426-SM-4AT4R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11822 skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -1.58914 NRD1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 0.903197 BL2762 (HNRNPU) NURSA Protein Complexes 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12806 Perturb_9088_KD_SUPT16H_SRP106869 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.29438 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 769-P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00447 Perturb_9817_KD_E2A_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.5406 primary motor cortex (area M1, area 4)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08485 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.36647 CCAR2_02_146 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.69188 DNAH8 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 BL4214 (THRAP3) NURSA Protein Complexes 1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11163 vesicle GO Cellular Component Annotations 2015 1.0 null primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.8174 Rectum adenocarcinoma_READ_TCGA-CL-5917-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.00378 hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0842 ZC3H7B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-VJWN-0426-SM-3GIJI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23596 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_3845_KD_lncRNAAF339830_SRP161584 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.12804 Perturb_8162_KD_SNRNP70_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.45572 GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19558 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0129 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.80825 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.48831 membrane LOCATE Curated Protein Localization Annotations 1.0 null RBFA Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 2.09106 fallopian tube HPA Tissue Gene Expression Profiles 1.0 0.924345 PALD1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12149_KO|OE_TP53|CENPA_ERP125655 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.81565 MYC Pathway Commons Protein-Protein Interactions 1.0 null Perturb_10667_OE_PAX3FOXO1_SRP371512 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.29096 Perturb_15101_KD_PDHA1_SRP385600 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.91543 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59332 inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.958517 PRKCDBP Pathway Commons Protein-Protein Interactions 1.0 null Perturb_96_KI_KMT2C_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.23747 GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 BUB1 Kinase Library Serine Threonine Kinome Atlas 1.0 null Perturb_7496_KD_EFTUD2_SRP192094 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.3542 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.870932 GTEX-U412-0326-SM-3DB9L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04062 Perturb_7780_KD_NUDT21_SRP017305 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.90158 GTEX-VUSG-2226-SM-4KKZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.38067 RUNX2 Pathway Commons Protein-Protein Interactions 1.0 null BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 Perturb_4759_KO_DLG2_SRP315088 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.08858 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49542 GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Perturb_8323_KD_INO80_SRP103083 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.94157 Perturb_3910_KO_ARID1A_ERP114370 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.22337 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4635-01A-02R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_9940_KD_MAK16_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.92637 ZNF586 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6750_KO|KD_IER5_SRP103746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.69816 stratum pyramidale of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01961 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7372-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14245 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24665 GTEX-XBEC-0008-SM-4AT3X GTEx Tissue Sample Gene Expression Profiles 1.0 0.874177 UQCRFS1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_628_KO_HOXD3_ERP117895 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.93868 GTEX-VUSG-0003-SM-3NMDK GTEx Tissue Sample Gene Expression Profiles 1.0 1.32692 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.65525 Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824704 ARID5B Pathway Commons Protein-Protein Interactions 1.0 null Perturb_5427_KD_ARID1A_SRP356912 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.42443 H3K9me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13597 GTEX-S7SE-0005-SM-2XCEA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23291 dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.25596 NPR1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U8XE-0005-SM-3DB8I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.876866 LBX2 Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.861285 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 2.22544 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Metabolic Syndrome X DisGeNET Gene-Disease Associations 1.0 null GTEX-XK95-0226-SM-4AT58 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829627 LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.21165 ATP6V1D Pathway Commons Protein-Protein Interactions 1.0 null GABRR1 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-A53B-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14885_KO_H12_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.56271 extracellular vesicle GO Cellular Component Annotations 2015 1.0 null H3F3A Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.83648 salivarygland_6b HPA Tissue Sample Gene Expression Profiles -1.0 -0.883646 Perturb_438_KO_HNRNPA2B1/HNRNPA1_SRP067568 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.8815 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.61513 extracellular organelle GO Cellular Component Annotations 2015 1.0 null IGF2BP2 Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2777-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 TPH1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7311_KO_TIP60_SRP386875 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.47298 extracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.53658 Perturb_13885_KD_CDK4/CDK6_SRP258989 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.38275 Perturb_17690_KD_MDMX_SRP393452 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.01299 GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.428 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 2.89259 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7367-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.60788 NCIH2087 CCLE Cell Line Gene Expression Profiles 1.0 2.06999 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04217 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.22311 Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBFOX2 Pathway Commons Protein-Protein Interactions 1.0 null EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.831556 PHF6 Pathway Commons Protein-Protein Interactions 1.0 null NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.38019 RPS16 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSD17B4 Pathway Commons Protein-Protein Interactions 1.0 null SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52224 GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.07903 granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14733 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05959 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02473 GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.940259 GTEX-W5X1-0426-SM-3GILB GTEx Tissue Sample Gene Expression Profiles 1.0 1.28843 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 AJAP1 Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.32801 Perturb_15562_KO_SLFN11_SRP327912 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.51351 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01977 GTEX-U3ZN-0826-SM-4DXSZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.10951 bewo HPA Cell Line Gene Expression Profiles -1.0 -1.68688 U266B1 CCLE Cell Line Gene CNV Profiles 1.0 1.51603 GTEX-WI4N-1026-SM-3LK7N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.95533 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2653 Perturb_14561_KD_UBE2C_SRP221206 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.16851 GTEX-XUJ4-0126-SM-4BOP7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25429 abnormality of the coronary arteries GWASdb SNP-Phenotype Associations 1.0 0.362487 FAF2 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-FB-A78T-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKMEL31 CCLE Cell Line Gene Expression Profiles -1.0 -1.52018 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.967983 OVMANA CCLE Cell Line Gene CNV Profiles 1.0 2.55781 gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.20816 Perturb_15402_KD_MELK_SRP098926 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.89016 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.983074 GTEX-O5YV-0006-SM-2I5GX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07801 connective tissue disease GWASdb SNP-Disease Associations 1.0 0.237689 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17291_OE_lncRNA5251_SRP239064 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.80146 FAM117B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PWCY-0726-SM-48TCS GTEx Tissue Sample Gene Expression Profiles 1.0 1.18454 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.884903 arteriosclerosis GWASdb SNP-Disease Associations 1.0 1.41484 TENM2 Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.932123 GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 0.940444 extracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-WXYG-2526-SM-3NB3F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.65877 ERBB2IP Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7384_KO|KD_SMG7_ERP122822 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_7381_KO|KD_SMG7_ERP122822 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-V1D1-1726-SM-4JBHB GTEx Tissue Sample Gene Expression Profiles 1.0 0.965489 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.34866 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8490_KD_CAG/CUG_SRP119324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.3768 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34915 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.0816 H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-UPK5-0326-SM-3GAF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829883 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.844496 CTCF ENCODE Transcription Factor Targets 1.0 null TMPRSS11A Pathway Commons Protein-Protein Interactions 1.0 null dorsolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1903 ELFN1 Pathway Commons Protein-Protein Interactions 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.39714 PGD Pathway Commons Protein-Protein Interactions 1.0 null GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08476 NCIH322 CCLE Cell Line Gene CNV Profiles 1.0 1.85724 magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.81023 GTEX-WFJO-0002-SM-3P61X GTEx Tissue Sample Gene Expression Profiles 1.0 0.945565 MRGBP Pathway Commons Protein-Protein Interactions 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_2496_KD_NXF1_SRP226431 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.81308 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.13618 Perturb_8238_KD_RBM25_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.37884 Perturb_7875_KD_H2A.Z.2_SRP259021 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.84966 testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.26927 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33451 GTEX-OXRK-0126-SM-3NB1E GTEx Tissue Sample Gene Expression Profiles 1.0 1.22618 HK1 Pathway Commons Protein-Protein Interactions 1.0 null EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ6-0226-SM-3P61I GTEx Tissue Sample Gene Expression Profiles 1.0 1.32061 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.73503 Perturb_10073_KD_SLBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.0985 GTEX-TML8-0008-SM-4DXUI GTEx Tissue Sample Gene Expression Profiles 1.0 0.837753 GTEX-U3ZN-2026-SM-4DXUC GTEx Tissue Sample Gene Expression Profiles 1.0 1.03721 GTEX-XBEC-1526-SM-4AT68 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18596 GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.834431 Perturb_14884_KO_H12_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.08595 Perturb_8159_KD_MTPAP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.63771 GTEX-RM2N-1626-SM-2TF5N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19289 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00485 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.89776 SBNO2 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.45807 TBL1XR1_02_178 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.62936 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64614 GTEX-NL4W-0011-R9a-SM-2I3G1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11706 MFE319 CCLE Cell Line Gene Expression Profiles 1.0 2.55826 Perturb_7932_KD_Spt6_SRP132004 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 NCIH660 CCLE Cell Line Gene CNV Profiles -1.0 -1.49247 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.936387 GFPT1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_708_KO_INTS6_SRP299234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.86379 Perturb_10058_KD_UCHL5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.09862 GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86254 Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.76045 H3K9me3_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17456 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05953 cell part GO Cellular Component Annotations 2015 1.0 null SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 BUB1 Pathway Commons Protein-Protein Interactions 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57466 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46382 QPCTL Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XV7Q-1826-SM-4BRUV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.912248 SARS-CoV_12Hour_20090954_GSE17400 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.86744 GTEX-XBED-1226-SM-4AT5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.900778 SNRPD2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-V1D1-1126-SM-4JBHT GTEx Tissue Sample Gene Expression Profiles 1.0 0.863344 GTEX-T5JW-0003-SM-3NMAD GTEx Tissue Sample Gene Expression Profiles 1.0 0.924032 Perturb_7682_KD_HNRNPK_SRP111756 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.82132 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.59058 Perturb_14874_KO_H12_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.2134 dorsolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10828 H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41788 OVMANA CCLE Cell Line Gene Expression Profiles 1.0 1.61627 GTEX-RU1J-1726-SM-2TF5S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33399 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.53342 Perturb_10025_KD_TIAL1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.18713 ZNF106 Pathway Commons Protein-Protein Interactions 1.0 null Fasting Blood Glucose Measurement DisGeNET Gene-Phenotype Associations 1.0 null Perturb_8104_KD_CPSF7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.481 FN1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.93473 NAV3 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_2128_KD_DDX41_SRP309134 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.3834 H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.845981 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.5889 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38685 muscle GTEx Tissue Gene Expression Profiles -1.0 -2.10021 TestisSeminiferousTubule BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.873895 anterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07918 layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16081 TNFRSF18 Pathway Commons Protein-Protein Interactions 1.0 null PRR11 Pathway Commons Protein-Protein Interactions 1.0 null EBC1 CCLE Cell Line Gene CNV Profiles 1.0 2.09525 GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20483 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.476569 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 3.42237 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 ARFGAP1 Pathway Commons Protein-Protein Interactions 1.0 null A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.85539 subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08701 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6442_KO_RHO_SRP134183 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.52034 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PITX2 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stratum lacunosum-moleculare of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.886221 ADAMTS20 Pathway Commons Protein-Protein Interactions 1.0 null NUP98 Pathway Commons Protein-Protein Interactions 1.0 null amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.27378 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.989808 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.35582 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.835854 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.964525 FANCM Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.977405 Metabolic Syndrome X dbGAP Gene-Trait Associations 1.0 0.836775 KMT2A Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15177_KD_CDH3_SRP366922 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.22881 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2782-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.56519 GTEX-X261-0126-SM-3NMD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.953613 GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17362 GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.867269 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.5437 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924172 extracellular vesicular exosome GO Cellular Component Annotations 2015 1.0 null NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38987 GTEX-V955-0126-SM-4JBH5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20117 YAF2 Pathway Commons Protein-Protein Interactions 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46923 GTEX-V955-0004-SM-3NMDH GTEx Tissue Sample Gene Expression Profiles 1.0 1.0324 skeletalmuscle_d HPA Tissue Sample Gene Expression Profiles -1.0 -0.997943 GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03913 GTEX-OHPK-1626-SM-2YUN3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.896484 Lung squamous cell carcinoma_LUSC_TCGA-66-2793-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AHNAK2 Pathway Commons Protein-Protein Interactions 1.0 null ABCA1 Pathway Commons Protein-Protein Interactions 1.0 null SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.911085 Perturb_15560_KO_SLFN11_SRP327912 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.4717 BL1244 (MAML3) NURSA Protein Complexes 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26239 SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28193 Perturb_9345_KO_CDKN2A_SRP158424 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.43765 TNR Pathway Commons Protein-Protein Interactions 1.0 null BCPAP CCLE Cell Line Gene Expression Profiles -1.0 -1.57255 GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.897333 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.602429 SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.40736 extracellular vesicular exosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21447 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33069 GTEX-Q734-0326-SM-48U15 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01347 Perturb_15211_OE_MIR130B_SRP373399 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.909 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52387 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.09927 EPC1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WFG8-0126-SM-4LVMH GTEx Tissue Sample Gene Expression Profiles 1.0 1.28532 G120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 Perturb_12108_KD_CCND1_SRP244245 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.06834 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05421 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.26642 ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.26175 ABCB1 Pathway Commons Protein-Protein Interactions 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9980_KD_RBM25_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.7374 Perturb_9854_KD_LUC7L3_ERP124746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.3822 GTEX-RVPU-2226-SM-2XCAQ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 Brain Lower Grade Glioma_LGG_TCGA-DU-6394-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.87298 TCCSUP CCLE Cell Line Gene CNV Profiles -1.0 -1.35223 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05556 Perturb_8368_KD_IGF2BP3_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.22096 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.876692 GTEX-P4PP-1526-SM-3P61M GTEx Tissue Sample Gene Expression Profiles 1.0 1.15237 HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20345 Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU175 CCLE Cell Line Gene Expression Profiles 1.0 1.49295 ST6GALNAC6 Pathway Commons Protein-Protein Interactions 1.0 null abnormality of the systemic arterial tree GWASdb SNP-Phenotype Associations 1.0 0.194196 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31279 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83136 ANLN Pathway Commons Protein-Protein Interactions 1.0 null Perturb_700_KO_INTS6_SRP299234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.76836 Perturb_8243_KD_SRSF9_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.00882 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.32895 DENND6B Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-3116 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 pc3 HPA Cell Line Gene Expression Profiles -1.0 -1.68688 KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20603 GTEX-U3ZM-0002-SM-3NMDM GTEx Tissue Sample Gene Expression Profiles 1.0 0.838357 Perturb_2291_OE_TBX3_SRP184219 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.66785 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.912115 HCC1806 CCLE Cell Line Gene CNV Profiles 1.0 2.20957 MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865223 Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMARCA5 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6842_KD_RALY_SRP234429 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.37357 inner CP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.95549 TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.73236 Lung squamous cell carcinoma_LUSC_TCGA-56-8628-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R3-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.8271 RPS27L Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4488 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Perturb_17620_KO_MLLT6_SRP245883 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 KARS Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CH-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06503 CYBA Pathway Commons Protein-Protein Interactions 1.0 null inherited blood coagulation disease GWASdb SNP-Disease Associations 1.0 0.531578 TUFM Pathway Commons Protein-Protein Interactions 1.0 null CDK5RAP2 Pathway Commons Protein-Protein Interactions 1.0 null H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.861178 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35951 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01511 GTEX-S4Q7-0226-SM-4AD5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.26111 Kidney Chromophobe_KICH_TCGA-KN-8430-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8835_KO_RING1A_SRP345831 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K9me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_8109_KD_MSI2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.07799 LAMA84 CCLE Cell Line Gene CNV Profiles -1.0 -1.52907 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0748 bonemarrow_6c HPA Tissue Sample Gene Expression Profiles -1.0 -1.98738 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.839182 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03823 LCN12 Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41723 Perturb_3638_KO_BRD2_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.99436 GTEX-X8HC-2726-SM-46MUA GTEx Tissue Sample Gene Expression Profiles 1.0 1.29049 INSM1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S7PM-0526-SM-3NM92 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03232 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.407 GTEX-T2IS-0226-SM-32QPH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.83503 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.860926 GTEX-XPT6-0001-SM-4B64G GTEx Tissue Sample Gene Expression Profiles 1.0 0.934986 ZBTB18 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-P44H-0226-SM-2XCEU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45702 GTEX-X638-0003-SM-47JZ1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.886398 GTEX-RUSQ-0226-SM-47JWT GTEx Tissue Sample Gene Expression Profiles 1.0 0.859175 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.80086 1min_EGF vs ctrl_HeLa (Human) [17081983] SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands 1.0 null Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.974702 IPC-298 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06503 ATM Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RWS6-0001-SM-3NMAL GTEx Tissue Sample Gene Expression Profiles 1.0 0.944539 mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07222 posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.905039 Perturb_11528_KD_ATAC1_SRP109127 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.1611 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11403_KD_CPT1A_SRP076884 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.39256 Perturb_13677_KD_DHX9_SRP018815 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05118 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.7519 DYNLRB1 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.829339 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.74133 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.874606 substantia nigra, compact part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855235 Perturb_8125_KD_LARP4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.10379 bone marrow HPA Tissue Gene Expression Profiles -1.0 -1.24894 Protein C Antigen Measurement DisGeNET Gene-Phenotype Associations 1.0 null EVSAT CCLE Cell Line Gene CNV Profiles -1.0 -1.32452 Perturb_511_OE_ACE2_SRP278541 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.9142 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 2.09041 POLG Pathway Commons Protein-Protein Interactions 1.0 null arterial stenosis GWASdb SNP-Phenotype Associations 1.0 0.31572 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.940088 GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.924481 GABP-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 0.964422 GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 PXR (PXR:RXR) MotifMap Predicted Transcription Factor Targets 1.0 null GLTSCR1 Pathway Commons Protein-Protein Interactions 1.0 null REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.58502 GTEX-R55F-1426-SM-2TF53 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31468 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41788 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06893 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.12339 GTEX-RNOR-0526-SM-2TF4O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01035 Prostate adenocarcinoma_PRAD_TCGA-G9-6343-01A-21R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8166_KD_CNOT7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.8861 H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.64252 MAP7D1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7670_KD_HNRNPK_SRP111756 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.35663 ARID4B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34539 primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.885329 Perturb_13496_KD_IGF2BP1_SRP252425 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.23212 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.09193 Perturb_10088_KD_PRPF6_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.5813 UT7 CCLE Cell Line Gene CNV Profiles -1.0 -2.22437 GTEX-PLZ5-1726-SM-2I5F6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20925 salivary gland HPA Tissue Gene Expression Profiles -1.0 -0.898808 Perturb_4352_KD_EP300_SRP068733 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.32071 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04109 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.04687 Lymphoma_burkitts(Daudi) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.04304 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles -1.0 -1.33794 intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50498 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02938 CEP170 Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-X6-A7WD-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null skeletal muscle HPA Tissue Protein Expression Profiles 1.0 0.733372 GTEX-X638-0008-SM-47JZ7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14991 Pancreatic adenocarcinoma_PAAD_TCGA-FB-A545-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5329-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.891513 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.886839 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05025 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.26519 ADNP Pathway Commons Protein-Protein Interactions 1.0 null KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.932665 GTEX-QVJO-1626-SM-2S1QW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.864118 GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.56345 GTEX-PW2O-0008-SM-48TEB GTEx Tissue Sample Gene Expression Profiles 1.0 1.15041 AP4B1 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.905044 Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4EO-0006-SM-3P5ZF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57742 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.41431 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9816_KD_ARID5B_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.16986 HCC1500 CCLE Cell Line Gene CNV Profiles -1.0 -1.9001 HOXB5 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WYJK-1726-SM-3NM9U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.940868 EXOSC1 Pathway Commons Protein-Protein Interactions 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897511 WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.6618 Perturb_8226_KD_EWSR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.78283 Prostate adenocarcinoma_PRAD_TCGA-HC-8216-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9701_KD_RTN4R_SRP368642 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.83391 LOX Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7516_KO_TFAM_SRP213924 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.95273 Perturb_9775_KD_FYB1_SRP361457 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.06201 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 H3K27me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1999 GTEX-X4XY-0006-SM-46MV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.98532 GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982836 stratum pyramidale of rostral CA3 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12106 Perturb_7701_KD_Spt6_SRP132004 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.58809 TUBB3 Pathway Commons Protein-Protein Interactions 1.0 null KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.858633 GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.849539 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00485 DYNC1LI1 Pathway Commons Protein-Protein Interactions 1.0 null IZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08608 Perturb_7949_Mut_BAZ1A_SRP100570 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.38694 Perturb_8111_KD_STAU1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.78623 Prostate adenocarcinoma_PRAD_TCGA-VP-A87K-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BL464 (AHCYL2) NURSA Protein Complexes 1.0 null CFL1 Pathway Commons Protein-Protein Interactions 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_8918_KD_ARID1A_SRP256204 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.93095 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4258_KD_HOXB13_SRP201342 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.81609 GTEX-RVPU-0008-SM-3NM8B GTEx Tissue Sample Gene Expression Profiles 1.0 0.970832 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52228 Perturb_8276_KD_UPF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.02348 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0179 GTEX-UJMC-1826-SM-3GADT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24135 Perturb_6897_KO_TP53/ZNF84_ERP125489 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.34535 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS21 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null