association	dataset	threshold value	standardized value
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89516
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	88.4737
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90822
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3047
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8594
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7055
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31411
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04533
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AC-82-PZ00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.83615
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.60053
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.75521
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7178
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7592
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8723
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-PRRX1-sequence_name_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF396	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75907
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HE-80-BQ08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.409472
CA-66-GI09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342997
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8718
GRK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36244
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80549
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.2137
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75499
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5473
SEC31B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25044
BAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86183
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.786
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.333
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35436
EP300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9591
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.87718
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5387
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
TSA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
GSE157049,GSE157051_6_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4632
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1988
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05884
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28648
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.53999
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07619
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CB-73-HZ47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.993119
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0284
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4879
TRMT44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73387
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8889
RBM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64875
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.937
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50366
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.2808
SPAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46281
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30828
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.544
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
Pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	2.53825
PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3	Rummagene Transcription Factor Associations 2026	1.0	null
PSMB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64333
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.201
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
ERG28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66298
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.91
GSE142684_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15462
Melanophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1322
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25938
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131565_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6867
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88123
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9856
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pharyngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22986
TFAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
Congenital myopathy 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.487072
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MALSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28593
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9925
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3852
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6593
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.767
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4826
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX1-sequence_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3671
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8622
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.635
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ZSCAN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1641
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3709
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84878
PMC9161725-Table_4.xlsx-EHF-CSAG1_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06219
BE-17-CS60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.32426
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.52459
Osseous plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Nuclear dicing body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26956
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.292
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.892
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
SMARCAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66854
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.635
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05511
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9811
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5813
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7914
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0833
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.201
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.572
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9843
496100663_TCx_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11403
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56305
ZNF280D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13373
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60564
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41677
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0512
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08996
TMEM63A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31952
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57688
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42486
Testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.476
QKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83771
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0668
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1028
GSE104022_3_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TEX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41595
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4357
LAMTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82828
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2448
monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
HEK-293F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
496100360_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09171
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3546
GSE95685_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3988
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.21345
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75304
GOLGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12307
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69398
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77044
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.849
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.404
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7646
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245142
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.941
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.88
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1785
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79858
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4862
FC-22-ZV65_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.354233
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63014
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19783
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6169
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.402
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9327
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4891
MACIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32669
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.20572
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.635
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7258
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.448879
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53423
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8126
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6067
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9489
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.937
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0541
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.7
RNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09188
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.258
Nephrosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.089
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6695
BC-70-BH47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319451
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6528
GSE167984,GSE167987_0_v_1_setd1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4331
KAT6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59639
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25466
DE-58-OW37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204086
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7956
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4118
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.435
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9786
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.089
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7205
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.089
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.6684
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1911
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.69
GIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33838
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2546
STX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34673
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08426
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LHX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61447
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.201
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65091
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30721
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.698
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30564
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.1496
Nephrotic syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.089
VC-19-YG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.44178
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0307
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.452747
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX2-sequence_name_MSX2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.089
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11768
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38456
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01378
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25027
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63888
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74847
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.798
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.635
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5177
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12311512-mmc3.xlsx-OE_VS_NC2-Gene_Names_DR1	Rummagene Transcription Factor Associations 2026	1.0	null
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41177
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0448
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2383
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4192
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80036
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3319
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61263
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55118
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SIX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08422
JD-12-CE09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350553
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35328
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.635
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.721636
JF-84-QZ64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.480684
AA-62-JP26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.868019
LPGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83651
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47015
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78058
496100456_TCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03436
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4736
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7567
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68862
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37193
GSE207787_1_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0533
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1098
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2458
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0041
GSE183271_4_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63027
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0366
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4122
PMC3470785-NIHMS377161-supplement-3.pdf-73-KLF11_KLF11	Rummagene Transcription Factor Associations 2026	1.0	null
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.201
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2IRD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02323
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.62118
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.635
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9856
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.123
FD-67-GI76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.508162
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.123
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.71
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2769
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11084
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.8519
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4089
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5405
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02554
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3148
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0518
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.659
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
KB-3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81853
GSE224439_1_v_3_adagrasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tongue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
Uniplex complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
Plastid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8258
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0897
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.089
Chloroplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4736
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6875
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9957
FZD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87386
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.829055
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2338
GPR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22346
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6545
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5956
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8375
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83344
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6515
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.696
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14153
YA-85-VH07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.5359
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5228
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2116
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345134
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
Terminal loop	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.082
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9924
monoatomic ion channel activity	GO Molecular Function Annotations 2025	1.0	null
ALKBH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00212
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04543
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8295
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.201
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2651
RND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41517
SCML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50818
DNAAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32494
ZFP69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89684
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87093
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45681
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.782
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6702
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2242
Pelvic organ prolapse (moderate/severe)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
RRAGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86196
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07319
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9513
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.59903
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9062
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.306
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8717
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3014
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5638
TMEM237	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17734
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.01952
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.635
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5048
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.52
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8752
PMC4172779-13048_2014_87_MOESM1_ESM.pdf-145-C9orf90_NAIF1	Rummagene Transcription Factor Associations 2026	1.0	null
ATPAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60504
SPATA33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65692
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.73468
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3322
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.635
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82939
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.3985
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5332
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.14006
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.378
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	1.3992
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Proteinuria	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.089
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5625
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.9494
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8634
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.635
496100379_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9839
YA-85-VH07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.699091
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94671
monoatomic cation transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.699
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8056
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
SMG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60408
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5485
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.3194
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.25579
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5373
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4389
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61313
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5529
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2026
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-389-MYCN_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10245467-mmc3.pdf-162-ZNF98_ZNF98	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.201
LPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7796
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723