association dataset threshold value standardized value Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21018 Perturb_16082_KO_Hoxa9_SRP090515 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.11029 DUSP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4391 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CEPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12015 GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.851229 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0597 Perturb_2095_KD_EIF4A3_SRP226707 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.02546 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSC4 CCLE Cell Line Gene CNV Profiles 1.0 2.42886 SPTLC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30836 GSE76425_0_v_5_lenalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.20217 KMRC20 CCLE Cell Line Gene CNV Profiles -1.0 -1.33502 COQ8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12089 abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.220987 MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9467 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.33408 RPAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82686 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2803 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26308 SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49356 superficial stratum of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84277 GTEX-Q2AG-0011-R2A-SM-2HMIT GTEx Tissue Sample Gene Expression Profiles 1.0 0.86604 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.0534 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.32165 GTEX-X638-0003-SM-47JZ1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0738 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.37471 PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CEP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41344 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.74559 PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null GSE211286_7_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null MPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54159 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X585-0005-SM-46MV3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57143 ATF3 ENCODE Transcription Factor Targets 1.0 null L-1236 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.94521 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0653 A_CA_04_2009_7dayMOI-10^3_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.6529 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Orbital area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17916 C22orf39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51722 Retrosplenial area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33268 MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3609 GBX2 ChEA Transcription Factor Targets 1.0 null GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null DNAJB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03719 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 3.08775 Ventral part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21971 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 1.56913 GTEX-WI4N-2726-SM-3LK7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845109 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null L-428 COSMIC Cell Line Gene Mutation Profiles 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.413 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KNS81 CCLE Cell Line Gene CNV Profiles -1.0 -1.84919 Atrophy CTD Gene-Disease Associations 1.0 1.31476 HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_14491_KO_Caprin2_SRP236878 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.73443 GSE210682_2_v_3_methadone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32851 CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100443_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.0906 GTEX-VUSG-0126-SM-4KL1X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45839 H3K27me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-590-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE85880,GSE85881_0_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01358 DCAF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58576 CTCF_GM12801_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null RAB1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19793 CTCF_GM12869_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPP1R26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14566 intermediate stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27899 hsa-miR-3680 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.61852 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X15G-0526-SM-3NMB7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.962202 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.866692 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2721 CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.950418 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null SW 48 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.938134 EIF4E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47933 IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.966488 Orbital area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0336 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CDC37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45273 VMRCRCZ CCLE Cell Line Gene CNV Profiles -1.0 -1.4819 CTCF_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PP-0626-SM-3NM9X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.826336 H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3291 GTEX-RU1J-1726-SM-2TF5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936567 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T2IS-1026-SM-32QP1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30689 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R53T-0426-SM-48FEM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.94286 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0954 GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 GTEX-SIU8-0526-SM-2XCDP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00521 AASDHPPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5397 LS-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTBP2 ENCODE Transcription Factor Targets 1.0 null K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.51329 Perturb_5261_KO|KD_Mir290a/Mir290b/Mir291a/Mir292/Mir292/Mir291b/Mir293/Mir294/Mir295|Tfap4_SRP326984 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.46153 ATP5F1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03247 GTEX-T5JC-2526-SM-4DM6G GTEx Tissue Sample Gene Expression Profiles 1.0 0.82429 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.833513 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05124 VPS37A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35111 CTCF_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37307 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRE11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.81558 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.71308 GTEX-W5X1-2526-SM-3GILC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19577 Agranular insular area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01399 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28169 induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42982 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4846 Perturb_11989_KO_Cd36_SRP227133 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.36369 CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Granule cell layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.095 NDUFS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38609 GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881577 Superior central nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49541 SMIM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24732 TTI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25094 ERH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11025 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.894504 membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03554 ETK-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940519 GTEX-TKQ2-0226-SM-4DM6V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889424 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null bone marrow HPA Tissue Protein Expression Profiles 1.0 1.98993 H3K27me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4597 H3255 COSMIC Cell Line Gene CNV Profiles 1.0 2.12225 GTEX-X261-0011-R8A-SM-4E3I5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.878691 anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11295 TAF1 ENCODE Transcription Factor Targets 1.0 null Erythrocyte Count dbGAP Gene-Trait Associations 1.0 0.231299 KDM4A ENCODE Transcription Factor Targets 1.0 null OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.19649 GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.94905 EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21 ChEA Transcription Factor Targets 1.0 null H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null F8A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52363 GTEX-N7MT-0011-R2a-SM-2I3GI GTEx Tissue Sample Gene Expression Profiles 1.0 1.01944 H3K9ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_18442_KD_YAP1/WWTR1_SRP303519 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.57207 GTEX-WQUQ-0006-SM-3MJF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16147 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32186 MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82842 GSE121043_0_v_1_aldh1a1_human RummaGEO Gene Perturbation Signatures -1.0 null RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3599 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08569 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SMIM10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84562 SF3B6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32694 cerebellar cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.932281 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.950074 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.073 ENTPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32003 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41698 Perturb_12337_KD_TFEB_SRP226507 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.4911 SCC4 CCLE Cell Line Gene CNV Profiles 1.0 1.69018 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18881 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMR6-0011-R7A-SM-32PKL GTEx Tissue Sample Gene Expression Profiles 1.0 0.845318 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.48897 Perturb_2720_KD_YAP1/WWTR1_SRP115100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.6805 H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3 MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.937211 posterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21888 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37964 H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.322435 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.937211 GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51876 GTEX-XXEK-1726-SM-4BRVB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46548 Perturb_7599_KO_CTNNB1_ERP109990 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.68924 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_2319_KD_PRPF8_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.39641 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null erythrocyte count GAD Gene-Disease Associations 1.0 null PIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68974 CTCF_GM10248_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HAL-01 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.71638 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07047 GSE127790_10_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null NFKB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6985 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3275 IM95 DepMap CRISPR Gene Dependency 1.0 4.25727 TUBE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15077 SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04704 CTCF_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874398 CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX8 ENCODE Transcription Factor Targets 1.0 null Pontine gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1531 GTEX-T2IS-2926-SM-32QPO GTEx Tissue Sample Gene Expression Profiles 1.0 2.54053 intergeniculate leaflet Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47338 inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.27029 CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MHH-PREB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LC4-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.69497 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM185PE DepMap CRISPR Gene Dependency 1.0 5.09705 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52558 Bed nuclei of the stria terminalis, anterior division, oval nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.374 DDAH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.388 mantle zone of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.4519 GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21032 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_773_Mut_ACLY_SRP403241 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.75005 YSCCC DepMap CRISPR Gene Dependency 1.0 3.77144 CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Specific developmental disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.812 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87148 CTCF_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD9A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27453 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.22746 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.5605 Bladder GTEx Tissue Gene Expression Profiles 2023 1.0 4.71513 chr14_59537907_C_T_b38 GTEx eQTL 2025 1.0 2.67761 CDK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.58298 CHD1 ENCODE Transcription Factor Targets 1.0 null Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.7212 H3K4me1_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null orbital frontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.925928 H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOGGUVW DepMap CRISPR Gene Dependency 1.0 2.73284 PRPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05201 OSBPL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24545 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21521 H2BC15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07314 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.50953 Perturb_2342_KD_BRCA2_SRP153058 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.14955 CUX1 ENCODE Transcription Factor Targets 1.0 null GTEX-T6MN-0011-R1A-SM-32QOY GTEx Tissue Sample Gene Expression Profiles 1.0 0.930308 CREM JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0021 Agranular insular area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01062 inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02124 mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.37717 GTEX-UPIC-0726-SM-3GADW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39462 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.3303 ZNF765 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23408 YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17269_KO_Rfx2_SRP066176 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.0803 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.85962 H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ARHGAP11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47702 GTEX-RTLS-0926-SM-2TF5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.915722 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19204 GCM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35165 H3118 DepMap CRISPR Gene Dependency 1.0 5.41039 SLC2A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27516 C10orf88 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05309 E2A_KO_GDS5084_401_mouse_DN2 thymocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.00639 GSE68925_1_v_0_fasudil_human RummaGEO Drug Perturbation Signatures -1.0 null IRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles 1.0 2.29902 ALG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52304 YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventral posterolateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.52301 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.20834 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0491 SKMM2 CCLE Cell Line Gene CNV Profiles -1.0 -2.23486 GTEX-RTLS-0826-SM-2TF5Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14078 GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.09503 Developmental disorder of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.812 HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC25A29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89791 FRS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.25484 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me1_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KDM4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04613 CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2326_KD_SF3B3_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.35202 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NL4W-0011-R8a-SM-2I3G4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.923812 EBC1 CCLE Cell Line Gene CNV Profiles 1.0 2.03717 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tapetum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.902 PFDN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86065 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.937994 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08156 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42706 GTEX-NL4W-0008-SM-4E3I2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877045 GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13881 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PCI6A DepMap CRISPR Gene Dependency 1.0 3.47363 CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Supravalvular aortic stenosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.171 PECAPJ34CLONEC12 CCLE Cell Line Gene CNV Profiles 1.0 1.34566 GTEX-T6MN-0626-SM-32PM9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.895998 Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84277 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.25968 H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMR6-0011-R1A-SM-32PKW GTEx Tissue Sample Gene Expression Profiles 1.0 1.01212 PPARG ChEA Transcription Factor Targets 1.0 null immune system disease GWASdb SNP-Disease Associations 1.0 0.059737 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1947 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10188 PMC10787250-BLOODA_ADV-2022-008899-mmc1.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_commonly_up-_or_downregulated_in_CBFA2T3_GLIS2_leukemia_GLIS2 Rummagene Transcription Factor Associations 2026 1.0 null RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R53T-0326-SM-48FEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08302 GSE153064,GSE153065_1_v_2_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.02457 KYAE1 DepMap CRISPR Gene Dependency 1.0 2.98748 HCC2998 DepMap CRISPR Gene Dependency 1.0 3.02156 TIGD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15221 GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 HCT116 DepMap CRISPR Gene Dependency 1.0 10.181 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9396 GTEX-QVUS-2826-SM-3GADB GTEx Tissue Sample Gene Expression Profiles 1.0 0.917651 IM9 DepMap CRISPR Gene Dependency 1.0 2.86076 H3K4me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QXCU-0006-SM-2TC5K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86453 Perturb_10988_KO_Gnpda2_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.58856 496100520_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.25219 r11 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13976 NCIH3255 CCLE Cell Line Gene CNV Profiles 1.0 1.51324 orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17205 SKRC31 CCLE Cell Line Gene CNV Profiles -1.0 -1.43311 organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Perturb_11316_KO_Noct_SRP120584 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.94611 PCI30 DepMap CRISPR Gene Dependency 1.0 3.40705 STX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58748 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.8564 XBP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.2211 GTEX-PWO3-0011-R6A-SM-2I5F3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2008 primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.30943 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.870396 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09562 DDX50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68454 A_CA_04_2009_4dayMOI-10^5_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.69684 CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDST8 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.87326 Orbital area, ventrolateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57388 Perturb_1808_KO_Arhgef2_SRP186268 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.17989 DACT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15857 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03528 SU-DHL-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.832122 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BL1870 (TRIP4) NURSA Protein Complexes 1.0 null abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.774448 GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.880542 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gustatory areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40868 Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59591 Submedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33134 layer 3 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33354 TRPS1_Mutation_GDS4493_594_mouse_Whisker pads GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MINDY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55192 DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XLM4-0011-R8A-SM-4AT44 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07617 LU65_LUNG CCLE Cell Line Proteomics 1.0 8.68014 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82842 GSE247764_5_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Reticular nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96505 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16472 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-POYW-0826-SM-2XCEM GTEx Tissue Sample Gene Expression Profiles 1.0 0.865924 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.33893 HLA-DQB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17765 MBTPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4892 ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3 Rummagene Transcription Factor Associations 2026 1.0 null SNU1272 CCLE Cell Line Gene CNV Profiles -1.0 -1.53946 GTEX-P44H-0011-R1A-SM-3NM8J GTEx Tissue Sample Gene Expression Profiles 1.0 0.994692 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03897 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0424 NDUFS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91066 C5orf15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21441 DESI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09224 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.950684 NRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11476 496100475_TCx_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05983 MAZ ENCODE Transcription Factor Targets 1.0 null GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 1.10532 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10812 mantle zone of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11493 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37677 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60247 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.19043 OACM5-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE166004_3_v_2_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3801 PGM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84443 GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 0.990548 RAD21_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null blood GTEx Tissue Gene Expression Profiles -1.0 -1.57852 ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7782 Secondary motor area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01433 Perturb_3877_KD_RELB_SRP333146 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.53223 EHBP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.70407 GTEX-R53T-0005-SM-3GADK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17739 GTEX-XBEW-0226-SM-4AT6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.04607 Perturb_12916_KO_Cbfb_SRP214434 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.54799 PKIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23976 Midbrain, behavioral state related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35117 Infralimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44471 CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sleep disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.952 GTEX-S7SE-0005-SM-2XCEA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.76481 GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00065 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_15101_KD_PDHA1_SRP385600 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.68827 mantle zone of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84277 GSE211286_1_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null Skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K27ac_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.28175 RAD21_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.64154 hsa-miR-519b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H3122 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.55885 H3K27me3_Rectal Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GLIPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.87384 RPSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32493 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28302 496100476_TCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.27772 H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03186 GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21649 posteroventral (inferior) parietal cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.88312 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85818 PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null UROS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72663 mantle zone of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94561 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.886779 all GWASdb SNP-Phenotype Associations 1.0 0.033688 GTEX-OIZH-1626-SM-2HMKI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36891 SLC44A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84712 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nucleus of the lateral lemniscus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02411 BCL7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60605 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE165647_0_v_1_cry2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30027 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.38756 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ2-0926-SM-4DXU5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.905597 FURIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04941 Pontine reticular nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10252 CTDSPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07614 DICER1_KO_GDS4504_582_mouse_bone marrow granulocyte-macrophage progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.35087 Perturb_5757_KO_C9orf72/Tmem173_SRP266242 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.65004 GTEX-RM2N-0326-SM-48FD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26099 PMC9894241-pnas.2211429119.sd05.xlsx-G8_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null GSE162590_1_v_0_gsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null shell part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49541 CTCF_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 2.22887 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PARP MotifMap Predicted Transcription Factor Targets 1.0 null MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.30031 DMS79 CCLE Cell Line Gene CNV Profiles 1.0 1.42283 PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR Rummagene Transcription Factor Associations 2026 1.0 null GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0351 GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles 1.0 0.9296 NAMALWA CCLE Cell Line Gene CNV Profiles -1.0 -2.19513 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68016 H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_15741_KO_Nr2e3_SRP086591 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE231648_4_v_5_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null PSMA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29567 GTF2F1 ENCODE Transcription Factor Targets 1.0 null MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.56574 anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17493 EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERGIC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38333 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TSPAN17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57978 mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12038 GTEX-QLQ7-1726-SM-2S1QQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01882 Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1441 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04513 INKA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04101 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.26894 TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5325 BICR78 COSMIC Cell Line Gene Mutation Profiles 1.0 null TRIM28_knockout_302_GSE32224 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.18421 GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13058 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.25837 CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5797 Perturb_8389_KO_Rnaseh1_SRP108593 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.85333 CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null rhombomere 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21888 Perturb_3122_KO_Slc6a14_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.09134 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 GTEX-XQ3S-0001-SM-4B64K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0835 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 r3 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13976 CREB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.799 superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1211 GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43513 CTCF_foreskin fibroblast_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null rostral secondary prosencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17886 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAB3A_KO_GDS2482_705_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HMBOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9316 GTEX-XPT6-0001-SM-4B64G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.054 NUDT21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7166 HIRIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09249 GTEX-S7SE-0011-R2A-SM-2XCDC GTEx Tissue Sample Gene Expression Profiles 1.0 0.990319 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0525 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CERT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69172 TE-10 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.82771 Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48093 Dorsal peduncular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61098 AGS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05443 GTEX-WWYW-0011-R10A-SM-3NB35 GTEx Tissue Sample Gene Expression Profiles 1.0 0.831831 GTEX-SJXC-0726-SM-2XCFJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.833371 MKN28 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X585-2426-SM-46MW2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10527 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.988152 Perturb_478_KD_PPARGC1A_SRP278736 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.86567 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.938306 GTEX-SN8G-1526-SM-4DM79 GTEx Tissue Sample Gene Expression Profiles 1.0 0.888471 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5655 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LB1047RCC DepMap CRISPR Gene Dependency 1.0 10.3989 GTEX-NFK9-0926-SM-2HMJU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.925472 GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles 1.0 2.34001 Perturb_2237_KO_Malat1_SRP193997 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.44187 HCC1833_LUNG CCLE Cell Line Proteomics 1.0 2.7227 CEBPE JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8986 superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71643 A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.07136 Major depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.472 E2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1356 GTEX-RU72-0926-SM-2TF6B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.859764 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.65556 rhombomere 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.73333 CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-2026-SM-4AT4X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1249 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.37369 FOXP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.263 HEY DepMap CRISPR Gene Dependency 1.0 2.39647 SOCS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.561 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940519 Perturb_3393_KO_Cblb_SRP347245 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.59934 IRF2BPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73195 NANOG_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U8T8-2226-SM-3DB95 GTEx Tissue Sample Gene Expression Profiles 1.0 0.968949 Perturb_10874_OE_LIPA_SRP328944 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.37255 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.99072 Vogt-Koyanagi-Harada disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.747 SIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95897 primary auditory cortex (core)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10482 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18063 NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.62517 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Infralimbic area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05753 ORC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29707 mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12258 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.979107 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.51295 NOA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.25159 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XOTO-0011-R1B-SM-4B65C GTEx Tissue Sample Gene Expression Profiles 1.0 0.926209 Retinal cone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.631 HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1272 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Secondary motor area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19142 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2565 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5148 PRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08998 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE76425_0_v_12_lenalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 2.30639 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.31949 EZH2 ENCODE Transcription Factor Targets 1.0 null ZNF567 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43513 Hypertrophy CTD Gene-Disease Associations 1.0 1.10246 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14849 CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARID3A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.27134 GTEX-PVOW-2526-SM-2XCF7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.8922 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4EO-0006-SM-3P5ZF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36212 Perturb_8764_KD_SLIT2_SRP158939 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.38428 GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.83317 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87148 LEPROTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39792 CTCF_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LHX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72051 CTCF_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null DOK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56353 H3K27me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 0.902724 PMC11112608-BLOODA_ADV-2023-011512-mmc1.pdf-24-ZNF471_ZNF471 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34804 H3K4me1_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CCDC87 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6947 PPP1CC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38576 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6772 WHAMM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3274 intracellular membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04373 GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 1.092 RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null icSARS-Cov_Day2_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.55881 GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52635 GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 r8 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21888 REPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5943 GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07742 COR-L26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.965002 GTEX-QV44-0526-SM-2S1RE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.834487 HS695T_SKIN CCLE Cell Line Proteomics 1.0 5.18055 GTEX-R55E-0011-R11A-SM-2TC6I GTEx Tissue Sample Gene Expression Profiles 1.0 2.39791 CTCF_GM12867_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06158 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.859764 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4525 H3K4me1_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NR2C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.2787 ASCC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21263 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SQ1_LUNG CCLE Cell Line Proteomics 1.0 2.03111 GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17696 ZNF282 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3806 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.872608 CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7PM-0006-SM-3NM8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24487 ZNF542P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25536 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7933 periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00134 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54109 Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52258 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2642 GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MM1S CCLE Cell Line Gene CNV Profiles -1.0 -1.59912 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.61497 GTEX-XLM4-0005-SM-4AT4P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09216 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-741-ENSG00000165588_OTX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-UPIC-1026-SM-4IHLT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18126 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.033766 GSE141328_1_v_0_rock2_mouse RummaGEO Gene Perturbation Signatures 1.0 null RPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69366 hsa-miR-3165 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3738 RERFGC1B DepMap CRISPR Gene Dependency 1.0 7.27427 CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null GTEX-QVUS-0011-R1A-SM-3GAD2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14895 r1 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.0051 ACTR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54897 GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48147 Infralimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74416 NDUFV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.22661 GSE138672_0_v_1_rabgef1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles 1.0 0.974004 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RL95-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null dorsal lateral geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4504 RSBN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36765 CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL4W-0011-R11A-SM-2I3DW GTEx Tissue Sample Gene Expression Profiles 1.0 1.57723 H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null liver HPA Tissue Protein Expression Profiles -1.0 -1.50097 hematological GAD High Level Gene-Disease Associations 1.0 0.295739 CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.28781 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null RAD21_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-2526-SM-2TC6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.60861 Bone_Marrow-myeloid progenitor Tabula Sapiens Gene-Cell Associations 1.0 0.284765 GSE152441,GSE152442_0_v_4_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null SPRY4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00544 GTEX-XOTO-0011-R11B-SM-4B64O GTEx Tissue Sample Gene Expression Profiles 1.0 1.87385 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10281 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55701 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cerebellum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00549 BCP1 CCLE Cell Line Gene CNV Profiles -1.0 -2.09788 SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82842 CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WY7C-2526-SM-3NB2N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02386 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.71304 PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null PEG10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23486 posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.87119 SSTR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47545 POLR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17547 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null AMIGO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45537 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.54943 H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CNNM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11913 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19204 SCC9 CCLE Cell Line Gene CNV Profiles 1.0 1.93819 H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.862921 CFAP119 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55415 TIE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42311 LC-2-AD COSMIC Cell Line Gene Mutation Profiles 1.0 null BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6234 PSMC3IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04533 GTEX-QESD-2026-SM-447BI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50218 HDAC2 ENCODE Transcription Factor Targets 1.0 null CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE211931_1_v_3_ncoa4_mouse RummaGEO Gene Perturbation Signatures -1.0 null MVK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50412 SMAD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5566 GTEX-N7MS-0011-R11A-SM-2HMJS GTEx Tissue Sample Gene Expression Profiles 1.0 1.85228 cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 3.70355 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03897 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6515 GTEX-SSA3-0005-SM-32QOT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30354 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.44151 ZNF440 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33234 GMS-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MARCKS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.26395 CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2666_KD_JUN_SRP357624 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.96061 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7616 intermediate stratum of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03668 CTCF_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCFL ENCODE Transcription Factor Targets 1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2A_Deficiency_GDS5084_271_mouse_DN2 thymocyte GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-XMK1-0005-SM-4B665 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.952314 GTEX-WHSE-0011-R4A-SM-3P5ZN GTEx Tissue Sample Gene Expression Profiles 1.0 0.856008 Perturb_5867_KD_Cpsf6_SRP336206 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.61118 Dorsal peduncular area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28874 Agranular insular area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71245 GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.79362 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-0011-R7A-SM-32QP5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.917435 HDAC1 ENCODE Transcription Factor Targets 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.42668 COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.58477 RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WY7C-2126-SM-3NB2R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.834722 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3738 cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.99914 GTEX-SJXC-0126-SM-2XCFF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855263 disease GWASdb SNP-Disease Associations 1.0 0.033207 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00838 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Spz1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.25 DNAJA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14201 r3 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04513 Taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32876 PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null TEAD4-22529382-TROPHECTODERM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null KYAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29592 GTEX-WVLH-0011-R11A-SM-3MJFO GTEx Tissue Sample Gene Expression Profiles 1.0 2.37447 GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.29527 mantle zone of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00352 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DCAF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47736 TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.036 HCC1359 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86077 SAT COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.1567 GSE179036_1_v_0_trim24_mouse RummaGEO Gene Perturbation Signatures -1.0 null KARPAS-422 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07343 GTEX-XBED-2626-SM-4E3J5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.867245 Perturb_15783_KO_Plagl1_SRP318611 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.41234 HIVEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10304 GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.72044 KURAMOCHI_OVARY CCLE Cell Line Proteomics 1.0 2.11697 ventrolateral prefrontal cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -3.04384 pontine hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89059 BCS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86374 ZC3H4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50421 NSA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25395 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SW1783 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.2524 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LOU-NH91 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.30778 CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of pedal digit skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.986747 mantle zone of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04513 YY1 ENCODE Transcription Factor Targets 1.0 null GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03653 GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2296 TGFBR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00846 H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF304 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74218 Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44053 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.898262 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hematopoietic system disease GWASdb SNP-Disease Associations 1.0 0.882152 GTEX-XYKS-0002-SM-4BRWN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0712 GSE223008_11_v_12_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Hindbrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.32628 TDOTT DepMap CRISPR Gene Dependency 1.0 2.26703 Perturb_314_KD_XBP1_SRP279319 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.00716 KMS20 DepMap CRISPR Gene Dependency 1.0 2.26222 CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7662_KD_CTCF_SRP072272 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.00609 NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32186 MYOZ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3112 rectum HPA Tissue Gene Expression Profiles 1.0 1.58168 Brain ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SHP-77 COSMIC Cell Line Gene Mutation Profiles 1.0 null MPV17L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07993 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_12936_KO_SPI1_SRP342114 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.69809 PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.909102 KURAMOCHI COSMIC Cell Line Gene Mutation Profiles 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09562 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.946061 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12865_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12866_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 CTCF_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.87977 Specific granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.211 CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X261-0626-SM-3NMD9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11032 GSE110676_0_v_4_mef2b_mouse RummaGEO Gene Perturbation Signatures 1.0 null ARL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8966 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25173 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.49675 GSE195513_2_v_1_cpeb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 OTUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02808 NEK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98222 GTEX-WHSE-0926-SM-3NMBS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.859507 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE102505_5_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-O5YV-0008-SM-4E3HP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11527 GTEX-OOBJ-0526-SM-48TDK GTEx Tissue Sample Gene Expression Profiles 1.0 0.894784 GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 0.931338 GSE112860_3_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null FOXD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3 THOC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17667 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.15863 intermediate stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29003 Atf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.5509 CPSF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8473 GTEX-XXEK-0526-SM-4BRWD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936071 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.28353 YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHH-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null membrane-enclosed lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 LONRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10187 Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94808 Perturb_12510_KD_BCDIN3D_SRP285644 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.39615 ATXN2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33541 YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLNS1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00122 GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles 1.0 1.53264 GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.980831 OVK-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZCCHC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16834 layer 5 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.355 CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUW1-0826-SM-4BOP6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05077 H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MED29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22429 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.89186 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.319221 H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SETD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42203 FZD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66777 CTCF_fibroblast of lung_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null zbtb7b_19734230_cd8_p14_memory_lof_mouse_gpl1261_gds3566 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.030565 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r3 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04513 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.7307 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE242521,GSE242522_0_v_1_mettl3_human RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09328 SHISA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41088 LTBR_INHIBITION - 35 Day_GDS2004_737_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NFATC2IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58713 H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null BDH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27538 KCNF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.58051 GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40653 ACTR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16943 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.10428 IPC-298 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.83742 ATF3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE173810_4_v_6_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NANOG ENCODE Transcription Factor Targets 1.0 null SIRT3_KO_GDS4817_416_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02441 Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0565 YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64739 GTEX-QEG4-0006-SM-2I5FY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34772 r6 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00352 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 3.00662 HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.93289 Perturb_6902_KD_Hdac5_SRP257918 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.86999 GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3865 H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35605 TUHR4TKB CCLE Cell Line Gene CNV Profiles -1.0 -1.82185 TT2609-C02 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XXEK-1126-SM-4BRUX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34372 Anterior cingulate area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28688 GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.867672 PPARG JASPAR Predicted Transcription Factor Targets 1.0 null laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17994 SMC3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null GTEX-QEL4-0626-SM-3GIJM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23895 VPS16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04699 r3 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94561 Agranular insular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17306 GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01335 layer 4 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21335 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null CTCF_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1036 ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBK-1026-SM-48TC2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.875883 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916374 GTEX-XV7Q-0008-SM-4BRWL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.878361 GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.25874 KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20511 hippocampus (hippocampal formation)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943758 posteroventral part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88307 r2 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17886 H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BICRAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35435 CTCFL_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.1874 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null KOPN-8 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.37215 GTEX-S7SE-0011-R6A-SM-2XCD9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.996547 GTEX-T5JW-1326-SM-4DM5G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.875021 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.472 TTLL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22841 H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.86061 Perturb_6520_KD_HES3_SRP162877 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.41737 CTCF_SK-N-SH_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Behcet's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.21 GTEX-Q2AI-1326-SM-2S1PL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02641 ZBTB7A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12871_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.852506 H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01673 IKZF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01288 CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Basement membrane collagen trimer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.593 LAMA2_Deficiency_GDS1778_747_mouse_Diaphragm (from dystrophia muscularis -dy/dy- mouse model) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74448 H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38715 NCI-H647 COSMIC Cell Line Gene Mutation Profiles 1.0 null CBX2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XLM4-2926-SM-4AT59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.82314 A253 CCLE Cell Line Gene CNV Profiles 1.0 1.39837 SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100305_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04211 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPM-1626-SM-2HMK4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24482 UNC5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.02985 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.992292 GTEX-TMMY-1226-SM-4DXT6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.946853 mantle zone of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1441 TE6 CCLE Cell Line Gene CNV Profiles 1.0 2.01434 ZNF862 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43952 Anteromedial nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36334 GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.14011 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.25832 Perturb_12362_KD_SNRPB_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.83719 TNFRSF18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08474 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68336 medial amygdala, anterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06172 TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8176 mantle zone of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56593 EXOSC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27937 GTEX-VUSG-2426-SM-4KKZG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.995253 abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.239235 medial part of r3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84277 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.32795 Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94718 ventrolateral prefrontal cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.75491 PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9767 ZC3H11A ENCODE Transcription Factor Targets 1.0 null Large_Intestine-enterocyte of epithelium of large intestine Tabula Sapiens Gene-Cell Associations 1.0 7.62432 PECAPJ41CLONED2 CCLE Cell Line Gene CNV Profiles 1.0 1.75752 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.0637 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.55615 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 GSE241701_2_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.88875 ALL-PO Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.5645 Dorsal part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18491 H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 0.97001 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OLIG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38672 NCI-H1299 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.959717 H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM193A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11977 KYSE410_OESOPHAGUS CCLE Cell Line Proteomics 1.0 2.71305 TMEM139 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0277 CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gustatory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18225 GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Mood disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.472 CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4699-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 Large_Intestine-intestinal crypt stem cell of large intestine Tabula Sapiens Gene-Cell Associations 1.0 0.284765 DPCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88457 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T8EM-1326-SM-3DB7G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.95146 superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40639 GTEX-QVJO-0011-R9A-SM-2S1QH GTEx Tissue Sample Gene Expression Profiles 1.0 0.972094 RAD21_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24584 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 3.24385 TMEM218 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15671 Perturb_1841_KO_Ifnar_SRP371304 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.61145 KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06709 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.986747 ELF1 ENCODE Transcription Factor Targets 1.0 null lymph node HPA Tissue Protein Expression Profiles -1.0 -1.50097 PDIA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2039 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12598010-Datasheet1.pdf-1-USF2_USF2 Rummagene Transcription Factor Associations 2026 1.0 null COLO684 DepMap CRISPR Gene Dependency 1.0 2.65522 DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1882 POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MCM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49789 B3GNT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.59135 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.28519 GTEX-UTHO-0726-SM-3GAEN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49699 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0011-R2A-SM-32QOW GTEx Tissue Sample Gene Expression Profiles 1.0 0.84002 lateral part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14146 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.73605 r4 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36774 GTEX-X5EB-0526-SM-46MVP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17956 ACVR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31062 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.45896 Depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.472 GTEX-OIZG-0005-SM-2HMJC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05557 SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null USP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11144 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.825361 GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles 1.0 0.830229 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18063 YY1-33199912-293T-HUMAN-KIDNEYEMBRYO ChEA Transcription Factor Targets 2022 1.0 null HYAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21909 DHX33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4612 Perturb_15136_OE_Mfn2_SRP313676 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.15009 Perturb_11534_KD_THOR_SRP121007 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.94622 cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.27029 PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1 Rummagene Transcription Factor Associations 2026 1.0 null Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02671 GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03934 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.974997 OCUB-M Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.61037 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1608 GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null COMMD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11808 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2504_KD_ELAVL1_SRP329920 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.70294 hsa-miR-4452 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.48614 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.36477 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19098 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20511 CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.11929 CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12873_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QT-1526-SM-3NMCT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909958 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.035105 CAL-148 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.62687 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCABER CCLE Cell Line Gene CNV Profiles 1.0 1.59434 GSE127790_6_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.62678 GSE138863_3_v_0_disulfiram_human RummaGEO Drug Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.42668 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.27453 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.65893 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.28085 GTEX-QDT8-0011-R7A-SM-32PKF GTEx Tissue Sample Gene Expression Profiles 1.0 0.88556 GSE85880,GSE85881_0_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WZTO-0011-R11A-SM-4E3K9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.66156 Dorsal peduncular area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07969 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19204 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.49983 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100304_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.17632 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88188 CENPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36001 GTEX-TKQ2-1826-SM-33HB2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.888726 Perturb_6521_KD_HES3_SRP162877 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.01638 ZFAND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2999 RPS19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22492 MED30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33086 NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69851 mantle zone of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54151 superficial stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54151 CAL-12T COSMIC Cell Line Gene Mutation Profiles 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52433 H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r5 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45497 RNASE6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47218 CTCF_GM12868_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2340_KD_BRCA2_SRP153058 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.77276 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.32597 r2 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.56294 chr14_59642862_A_G_b38 GTEx eQTL 2025 1.0 2.57593 R3HCC1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1328 MXI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -5.24138 GTEX-X88G-0004-SM-47JZ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43705 Perturb_10238_KO_Crat_SRP394715 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.51223 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.44579 H3K9ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF106 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72364 NB14 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.64862 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ7-0011-R2a-SM-2I3GF GTEx Tissue Sample Gene Expression Profiles 1.0 0.908587 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.18686 MFSD13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09646 SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_WI38_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.27519 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1726 KLF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34708 OTUD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3895 HLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08612 RNF123 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46094 Ventral posteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.03468 GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE161771_0_v_1_secretin_mouse RummaGEO Drug Perturbation Signatures 1.0 null PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4 Rummagene Transcription Factor Associations 2026 1.0 null Prelimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20549 NUP43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55678 QPCTL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.46157 anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12038 YY1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMD1-0011-R8A-SM-4AT48 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18779 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.358571 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.980205 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.90721 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.68898 r4 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43626 SFXN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62874 intermediate stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03438 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.81788 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8105 GTEX-RVPV-0011-R11A-SM-2TF6F GTEx Tissue Sample Gene Expression Profiles 1.0 2.16055 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.923495 SETDB1 ENCODE Transcription Factor Targets 1.0 null Perturb_10651_KD_Syncrip_SRP065017 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.39166 CTCF_A549_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null DBNDD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.50833 GTEX-WRHU-1226-SM-4E3IJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04739 Perturb_2077_KD_PUM2_SRP072710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.88484 CXCL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00099 superficial stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43626 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.962018 SPEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42806 GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 HOXC13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.865 SEC24A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87207 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27858 GTEX-RNOR-0011-R9A-SM-2TF52 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05948 CHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58753 Hypothalamic lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59109 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07863 STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20486 muscle GTEx Tissue Gene Expression Profiles -1.0 -0.9793 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRFAP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05464 Orbital area, ventrolateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6589 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100573_HIP_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.21644 fallopian tube HPA Tissue Gene Expression Profiles 1.0 1.23388 SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.79364 Perturb_17260_KO_Gja1_SRP247546 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.871548 KYSE-70 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65066 GTEX-X4XY-0008-SM-46MVL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910766 intermediate part of r2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65066 HCFC1 ENCODE Transcription Factor Targets 1.0 null SMG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12404 MED8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54906 intracellular part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE195559_2_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null PC3 CCLE Cell Line Gene CNV Profiles 1.0 1.6185 dorsolateral prefrontal cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22897 Elf5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.7788 HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18393 Anxiety Disorders CTD Gene-Disease Associations 1.0 1.37047 YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pons Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.73333 SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9865 NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5602 Orbital area, lateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62788 SKCO1 CCLE Cell Line Gene CNV Profiles 1.0 1.8541 Bone_Marrow-hematopoietic stem cell Tabula Sapiens Gene-Cell Associations 1.0 1.14264 CTCF_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterior cingulate area, ventral part, 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32226 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 heart disease GWASdb SNP-Disease Associations 1.0 0.882152 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.986391 intracellular non-membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 RAB3A_Mutation - D77G point mutation_GDS2482_702_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.413 VMRCRCW CCLE Cell Line Gene CNV Profiles -1.0 -2.82884 cytoplasmic part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 FGF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01913 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12875_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837205 primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03856 CTCF_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5X1-0006-SM-3GIJZ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 CALM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28035 PRMT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05195 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6495 CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VUSG-1426-SM-3GIJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53171 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.77696 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.11078 GSE166004_3_v_6_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RU72-2926-SM-2TF66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.43728 GTEX-X585-0011-R6A-SM-46MVJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.872073 GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09925 CXCL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76537 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.825191 RTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81862 GTEX-WFG8-1726-SM-4LVM6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11416 r3 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47467 lateral ventricle HPA Tissue Protein Expression Profiles 1.0 1.98993 GSE94849_1_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null Pons, motor related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.73333 GTEX-WWYW-0011-R5A-SM-3NB3E GTEx Tissue Sample Gene Expression Profiles 1.0 0.894581 Perturb_15747_KO_Cnga1_SRP327351 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.5475 SLC66A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33752 H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5177 TEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40646 CTCF_A549_hg19_10 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.13823 GTEX-SIU8-0006-SM-2XCE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 Perturb_12361_KD_SF3B5_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.41795 posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10482 YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RIMS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0601 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCM2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74786 Superior central nucleus raphe, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13976 ventrolateral part of alar m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11493 OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 2.51584 RAD21_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12865_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Melancholic depression DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.472 SCML1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1938 Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.3212 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09562 H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Retrosplenial area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03497 GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908941 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-TSE9-0011-R9A-SM-3DB7Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.04367 medial part of r4B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54151 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_12365_KD_WBP11_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.21321 Parasubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49541 496100432_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02082 Urogenital Abnormalities CTD Gene-Disease Associations 1.0 1.13621 H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-0011-R3a-SM-33HC6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.827313 GTEX-U4B1-0726-SM-4DXUA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.933912 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-2526-SM-32PMN GTEx Tissue Sample Gene Expression Profiles 1.0 1.65419 GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59258 TEAD4 ChEA Transcription Factor Targets 1.0 null Perturb_7957_KD_ZCCHC8_SRP222099 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.61192 KRAP_Deficiency_GDS3527_566_mouse_Brown adipose tissues GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 1.05204 GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 Perturb_11933_KD_RNF5_SRP276909 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.52834 MORN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06576 CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null CRACR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12186 Perturb_2231_KO_Irs1_SRP125007 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.40261 intermediate stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.42769 MFE-296 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles 1.0 2.11548 amygdaloid complex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.987843 GSE127790_5_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 2.91214 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.937743 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null DICER1_KO_GDS4504_584_mouse_bone marrow granulocyte-macrophage progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Geniculate group, ventral thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30981 AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null GJD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94398 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14849 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.907654 CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAHD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41127 GTEX-OOBJ-0006-SM-2I3F4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01564 Perturb_4256_KD_NCOR2_SRP326059 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.74796 GTEX-R55G-2426-SM-2TC5I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.96794 GSE162892_3_v_2_isox_human RummaGEO Drug Perturbation Signatures 1.0 null Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.4196 EM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.56711 USP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01171 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19169 KM-H2 COSMIC Cell Line Gene Mutation Profiles 1.0 null THAP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05357 Perturb_3875_KD_PLK4_SRP333146 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.319 VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2229 GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 MSTO-211H Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.81816 Taenia tecta, dorsal part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07335 nucleus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 G142 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24281 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.01411 amygdaloid complex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.05068 GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.48309 NCIH2126_LUNG CCLE Cell Line Proteomics 1.0 2.16533 VHL_Deficiency_GDS3769_513_mouse_Immortalized embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0219 cerebellar cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.859339 H3K4me1_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-NPJ7-0011-R10A-SM-2I3E5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.915785 Perturb_6651_KO_Kat7_SRP163302 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.38943 CCNT2 ENCODE Transcription Factor Targets 1.0 null SRSF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3415 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09924 PNN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61289 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null GK_KO_GDS1555_127_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE184087_4_v_5_tert_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.36928 Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.02032 GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 r3 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01358 GTEX-PWCY-0926-SM-48TD7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.989625 NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.472 GSE210870_0_v_2_snai1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.10573 UTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20972 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.055885 HARA COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01961 CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RNF2 ENCODE Transcription Factor Targets 1.0 null MIF_DEPLETION_GDS3626_95_human_HEK293 kidney cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23661 UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6702 STARD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71429 AOB, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16059 DZIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30406 CTCF_GM20000_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.965002 COLO 849 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.972445 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-292-OTX2_OTX2 Rummagene Transcription Factor Associations 2026 1.0 null Ventral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83645 Pons, behavioral state related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84277 r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71643 FOXM1 ENCODE Transcription Factor Targets 1.0 null GTEX-T5JC-0011-R11A-SM-32PMB GTEx Tissue Sample Gene Expression Profiles 1.0 1.96968 NCIH2141 CCLE Cell Line Gene CNV Profiles 1.0 1.90348 CTCF_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null FADU COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.42887 KMRC2 CCLE Cell Line Gene CNV Profiles -1.0 -1.3752 CTCF_GM12872_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MS-2526-SM-2D7W3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.79361 CTCF_WI38_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG8-0426-SM-3GILD GTEx Tissue Sample Gene Expression Profiles 1.0 0.84256 hippocampus (hippocampal formation)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.45246 GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1304 COSMIC Cell Line Gene CNV Profiles 1.0 2.12225 MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERGIC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56317 r5 part of the oral Sp5 subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43626 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMR6-0011-R6A-SM-32PKP GTEx Tissue Sample Gene Expression Profiles 1.0 1.01351 superficial stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66532 r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40821 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null HOP-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.912705 r3 part of reticulotegmental nucleus, shell portion Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35117 CBX2 ENCODE Transcription Factor Targets 1.0 null INO80E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3791 LHX1_KO_GDS2748_298_mouse_embryonic renal vesicles GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PIK3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67045 H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SIX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34113 GTEX-WWYW-0011-R11A-SM-3NB38 GTEx Tissue Sample Gene Expression Profiles 1.0 1.85556 MARK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39173 GTEX-OXRN-0011-R10A-SM-2I5GC GTEx Tissue Sample Gene Expression Profiles 1.0 0.859228 GSE184087_4_v_1_tert_human RummaGEO Gene Perturbation Signatures -1.0 null LYSP100-associated nuclear domain COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.745 OE21 DepMap CRISPR Gene Dependency 1.0 2.47851 CORL105_LUNG CCLE Cell Line Proteomics 1.0 4.95612 ZNF800 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0381 GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.11218 pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4289 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30984 GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null network-forming collagen trimer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.541 GTEX-X4XY-0006-SM-46MV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1712 GSE164505,GSE164506_3_v_1_indisulam_human RummaGEO Drug Perturbation Signatures 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.987504 Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33557 GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68588 GATA1 ChEA Transcription Factor Targets 1.0 null Retrosplenial area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57292 Perturb_6891_KD_PIRIN_SRP375440 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 16.3985 Collagen network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.577 CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.76508 OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.46782 intermediate stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47467 NCI-H1436 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.31326 RPL23A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64294 liminal part of r4 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06755 CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0726-SM-3DB8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37871 GSE127790_4_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null SKN-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3265_KO_Tet2_ERP013684 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.55064 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.01118 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.74173 SCC9 DepMap CRISPR Gene Dependency 1.0 8.0507 Perturb_12140_KD_PRPF8_SRP093921 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 TEX41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81605 POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cd8 cells HPM Cell Type and Tissue Protein Expression Profiles 1.0 1.14787 GTEX-WHSE-0011-R8A-SM-3P5Z1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.987779 GTEX-RN64-0326-SM-2TC5J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846844 IM-95 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-UTHO-0011-R5A-SM-3GIJD GTEx Tissue Sample Gene Expression Profiles 1.0 0.825273 CEBPB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9187 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5902 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NAALADL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45968 IMP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2614 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null TE10 CCLE Cell Line Gene CNV Profiles 1.0 1.97668 Perturb_1057_KO_Bcl9/Bcl9l_SRP045828 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.3855 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null NCI-H508 COSMIC Cell Line Gene Mutation Profiles 1.0 null PER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38375 r5 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12686 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17956 CTCF_fibroblast of foreskin _hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Agranular insular area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67674 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CXXC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0026 CAPAN1 CCLE Cell Line Gene CNV Profiles 1.0 1.43709 GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28829 CTCF ENCODE Transcription Factor Targets 1.0 null Puberty, Precocious CTD Gene-Disease Associations 1.0 1.36361 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.36388 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.48461 Perturb_12137_OE_Wdr11_SRP113332 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.73903 layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09545 GTEX-U4B1-1626-SM-3DB8N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.955609 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.875953 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Axon collateral COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.834 Bone marrow TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.930458 EEF1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54831 GTEX-X585-0011-R2B-SM-46MVF GTEx Tissue Sample Gene Expression Profiles 1.0 1.01352 GSE189683_1_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XUW1-1326-SM-4BOO1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.961143 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.6448 cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 CTCF_GM12870_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-208b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 RBBP5 ENCODE Transcription Factor Targets 1.0 null GSE191015_0_v_2_gsdmb_human RummaGEO Gene Perturbation Signatures 1.0 null MGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14485 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12865_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3121_KO_Slc45a3_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.21641 suboptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54151 liminal alar domain of m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11493 MAFK ENCODE Transcription Factor Targets 1.0 null DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37462 GSE127790_9_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-VUSG-0003-SM-3NMDK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39134 GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.65911 CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null GTEX-XYKS-0005-SM-4BRUD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.852252 PPM1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22435 GSE191015_0_v_3_gsdmb_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14737_OE_ADAR1_SRP250165 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.42873 CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null salivary gland HPA Tissue Protein Expression Profiles -1.0 -2.6949 cerebellum HPA Tissue Protein Expression Profiles 1.0 1.98993 H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null COMMD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25911 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18184 CAPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04953 ATM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5585 GBX2-23144817-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SP4 ENCODE Transcription Factor Targets 1.0 null hsa-miR-208a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 cytoplasm COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TUHR10TKB CCLE Cell Line Gene CNV Profiles -1.0 -1.32385 GTEX-XYKS-2126-SM-4E3IB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935771 GTEX-QCQG-1726-SM-3GIJ9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2503 GTEX-QMRM-0926-SM-447BR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.983511 YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE133087_1_v_0_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-0011-R11A-SM-2HMKZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.67104 PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XUJ4-1826-SM-4BOOU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.864212 SIN3A ENCODE Transcription Factor Targets 1.0 null GTEX-PLZ6-1426-SM-2S1OQ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.39336 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.987504 CW-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.858133 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14595 23132/87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.22013 GTEX-S7SE-0011-R7A-SM-2XCDI GTEx Tissue Sample Gene Expression Profiles 1.0 0.863097 POLR2J2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14048 CTCF_GM12875_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01952 HCC70_BREAST CCLE Cell Line Proteomics 1.0 2.59255 HOP-92 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QLQW-1326-SM-2S1QS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.988994 SNU119 CCLE Cell Line Gene CNV Profiles 1.0 1.58164 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null S1PR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32839 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32044 IRF1 ENCODE Transcription Factor Targets 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.79765 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11688 Perturb_691_KD_PTPN6_SRP275597 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.90268 Central lateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26101 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.29861 PI4KB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36571 H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_1298_KO_SOX15_SRP049465 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.59466 CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CFAP20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.65209 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.36934 GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZI-0426-SM-2XCEF GTEx Tissue Sample Gene Expression Profiles 1.0 0.875649 LRRC61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09916 RCOR1 ENCODE Transcription Factor Targets 1.0 null LS 174T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.3133 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.15488 GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 0.957518 hsa-miR-519a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GTEX-X4LF-0006-SM-3NMCO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13528 SENP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55584 ventral nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43075 CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-0626-SM-48FD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15317 HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.35358 Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07838 NCI-H82 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.23996 KLHL36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80634 JAK2_knockout_79_GSE26188 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.05683 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6319 ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42798 LS 174T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02897 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08589 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.48261 TAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84805 HOXA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05488 BNC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93901 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T2IS-0011-R11A-SM-32QPC GTEx Tissue Sample Gene Expression Profiles 1.0 2.3639 intracellular organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-XXEK-2226-SM-4BRUM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.938571 GTEX-T2IS-0011-R3A-SM-32QPB GTEx Tissue Sample Gene Expression Profiles 1.0 0.88603 GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57067 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.993048 GSE102505_5_v_0_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARID3A ENCODE Transcription Factor Targets 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.16138 TNRC18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84361 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 CTCF_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.26862 GTEX-QVUS-0226-SM-3GIJY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88466 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_16083_KO_Hoxa9_SRP090515 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.12938 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.26324 G402_SOFT_TISSUE CCLE Cell Line Proteomics 1.0 3.26687 Purkinje layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.323 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6311 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3502 UFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20107 GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 1.0621 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940519 SPPL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25659 ZNF341 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47338 DMD_Deficiency_GDS2996_613_mouse_Cardiac muscles from 8-week (mdx animals) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ITGA7_OE_GDS3209_142_mouse_skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BID CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79029 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.06154 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27651 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.18859 GTEX-X585-0011-R10A-SM-46MUY GTEx Tissue Sample Gene Expression Profiles 1.0 0.864461 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12725 amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.840644 GTEX-UTHO-0011-R1A-SM-3GIJO GTEx Tissue Sample Gene Expression Profiles 1.0 0.917624 GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 1.47854 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.18493 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2289 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.23036 GSE231648_0_v_5_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null Gustatory areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2305 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01303 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963888 KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32186 CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA4_KO_GDS3486_483_mouse_jejunum GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.50097 CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Reflex, Abnormal CTD Gene-Disease Associations 1.0 1.30421 OCT4_KD_GDS1824_135_mouse_embryonic stem (ES) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Initial pursuit acceleration in psychotic disorders GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.639794 SCN1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1155 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 1.05707 GLG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07073 NCI-H1573 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH28 CCLE Cell Line Gene CNV Profiles -1.0 -1.64892 GTEX-T6MN-0011-R6A-SM-32QP8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.993039 primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.890459 mantle zone of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07838 Perturb_3114_KO_Rabl6_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.45364 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RFX5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.27852 KCTD17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84541 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.2594 H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3484 CREB3L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2092 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.12095 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.899733 GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81659 H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pontine reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45497 medial part of r2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56593 CTBP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00025 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2957 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4517 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 T3M10 CCLE Cell Line Gene CNV Profiles 1.0 2.47661 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.03274 SMC3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_10241_KO_Crat_SRP394715 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.92096 ZNF382 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.0579 ZNF112 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3368 H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IRF6_KO_GDS2359_126_mouse_skin E17.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8179 ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5579 CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940519 nuclear part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 CTCF_fibroblast of villous mesenchyme_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.10849 GTEX-OOBJ-1026-SM-3NB2L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00207 Perturb_11140_KO_Myc/Mlxipl_SRP148418 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.09332 CTCF_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HT-55 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.32163 E2A_KO_GSE43224_679_mouse_DN2 cells from WT and E2A-deficient murine fetal thymi GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PRRC2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60985 GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 1.81569 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.834942 Perturb_10767_KO_Nrf2_SRP311380 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.92574 r10 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10769 Perturb_2330_KD_SNRPB_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.51379 IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.8656 PHB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44215 NCI-H835 COSMIC Cell Line Gene Mutation Profiles 1.0 null TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5246 SNUC1 DepMap CRISPR Gene Dependency 1.0 2.07552 Perturb_15325_KO_Setd2_SRP251920 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.42321 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.93122 H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12008_KO_B2_Mm2_SRP374407 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.96835 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.34084 GSE128099,GSE128159_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null r2 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21888 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB3L4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4282 Gustatory areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46628 GSE196117_6_v_0_clarithromycin_human RummaGEO Drug Perturbation Signatures 1.0 null RAD21_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.4257 CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRTC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17563 NPIPB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12422 GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16897 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Orbital area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41099 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.37038 cone-rod dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.439 GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.72909 Orbital area, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41606 CTCF-33576154-HUMAN-LIVER-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null mantle zone of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49541 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87148 Perturb_2096_KD_TENT4A_SRP237261 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.68337 periventricular stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07969 GAL3ST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38584 HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.866 chr14_59576335_C_T_b38 GTEx eQTL 2025 1.0 1.33954 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X88G-0126-SM-47JZ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842366 H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZEB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05939 ATN-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null RAD21_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-2326-SM-2TF4I GTEx Tissue Sample Gene Expression Profiles 1.0 0.826718 SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973424 ABHD15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53441 superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42982 GTEX-UPJH-0006-SM-3GACW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11813 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCAPH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33995 Potassium Dichromate CTD Gene-Chemical Interactions 1.0 null Ventral posterolateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.83101 COLO-741 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null CSNK1E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.50465 GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.08508 GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2646 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null r2 part of the ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16616 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 SDF2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06509 BC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HMGN3 ENCODE Transcription Factor Targets 1.0 null DMRT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79667 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.08712 H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.26677 Perturb_13108_KO_Mbnl1/Mbnl2_SRP045573 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.63479 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5774 SNRPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23911 IER2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35403 ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6614 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08599 GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12784 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lateral ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JC-0011-R8A-SM-32PLM GTEx Tissue Sample Gene Expression Profiles 1.0 0.854936 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.42779 EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q734-0426-SM-48TZX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63048 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RCC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.50174 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XBEW-0002-SM-4AT5O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.906208 ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5234 NFE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33912 GATA1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Metencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-OOBK-0726-SM-3LK5Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0911 H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.42725 Cco TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.642 primary motor cortex (area M1, area 4)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.14888 CTCF_MCF-7_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null WRNIP1 ENCODE Transcription Factor Targets 1.0 null GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08519 MRPL57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85427 CTCF_HEK293_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE217363_5_v_1_nlrp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04004 COR-L321 COSMIC Cell Line Gene Mutation Profiles 1.0 null LOUNH91 CCLE Cell Line Gene CNV Profiles -1.0 -1.56044 H3K4me1_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68388 H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.7576 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.26109 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2959 CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH82 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 TMEM245 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85766 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.27195 MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles 1.0 3.11485 SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null FAU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04303 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 1.0912 GSE63048_11_v_12_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TCTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10731 SAP30 ENCODE Transcription Factor Targets 1.0 null CTCF_astrocyte of the spinal cord_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SARDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27187 ARG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7088 CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_693_KD_SREBP1_SRP064735 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.74363 HSC4 DepMap CRISPR Gene Dependency 1.0 15.689 GTEX-R55D-0926-SM-3GAEU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825507 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837205 H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2BC26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.62887 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3756 SKMEL19 DepMap CRISPR Gene Dependency 1.0 4.94564 YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_11716_KD_GATAD2A_SRP194625 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.7444 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 Intergeniculate leaflet of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04214 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.063433 hsa-miR-519c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Thalamus, sensory-motor cortex related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34186 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.900361 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null chr14_59680174_A_G_b38 GTEx eQTL 2025 1.0 3.12689 PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3023 r5 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16616 GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52911 STX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20183 H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.13382 NCI-H82 COSMIC Cell Line Gene CNV Profiles 1.0 2.12225 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles 1.0 1.81408 IRF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.17794 CEMIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41786 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.97412 DPM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99476 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15706 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pyramidal layer of taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66681 superficial stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.16705 lateral part of r1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00352 GTEX-OHPN-0005-SM-2YUML GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25847 GTEX-TML8-0005-SM-32QPA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.65561 GTEX-XLM4-3026-SM-4AT6L GTEx Tissue Sample Gene Expression Profiles 1.0 0.924805 CAPZA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -5.75392 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 orbital frontal cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.987843 NENF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5285 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QVUS-0011-R9A-SM-3GIJA GTEx Tissue Sample Gene Expression Profiles 1.0 0.950845 GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.82005 H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_14161_KD_BZW1/BZW2_SRP316321 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.6385 Perturb_771_KD_SRRM1_SRP366559 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.20717 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain morphology (MOSTest) GWAS Catalog SNP-Phenotype Associations 2025 1.0 7.6 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P44H-0011-R8A-SM-2XCEL GTEx Tissue Sample Gene Expression Profiles 1.0 0.939899 mantle zone of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00352 EIF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19318 Nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00352 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SLC44A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32154 CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_11717_KD_MBD2_SRP194625 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.6407 MIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.6094 alar plate of p3 (alar prethalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17994 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WVLH-2926-SM-3MJG5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.96553 EIF3I CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28445 insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12368 RAD21_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRL-0326-SM-2I3F2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.937845 POU2F2_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA1 ENCODE Transcription Factor Targets 1.0 null Perturb_13824_KO_Nf1/Pten_SRP302970 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.67556 GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 1.07253 SLITRK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73152 Taenia tecta, dorsal part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67326 ERBB2_druginhibition_7_GDS2139 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.20834 GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28475 HS 852.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.20221 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26141 Perturb_2114_KD_SF3B3_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.1386 GSE242199_9_v_5_ntrk2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE162892_3_v_2_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null Collagen type IV trimer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.603 PNKD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.53877 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1119_OE_RUNX1_ERP106519 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.68813 H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17514 COLO-800 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.42869 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.46198 GSE215086_0_v_1_batf_human RummaGEO Gene Perturbation Signatures 1.0 null PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4147 GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00375 Brain small vessel disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.47 H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X3Y1-0006-SM-3P5ZG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06665 TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles 1.0 0.901474 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LRRC45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23661 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.799 Perturb_17585_KO_Nubpl_ERP016523 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.48172 H3K4me1_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null HA-E2F1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7SF-0001-SM-3K2BE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24098 ventrolateral prefrontal cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.37144 GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles 1.0 1.68677 Primary B cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.79422 GTEX-X261-3226-SM-3NMC3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.950298 CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VCaP Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.45583 KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04373 OC-314 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.63119 A704 CCLE Cell Line Gene CNV Profiles -1.0 -1.65566 CTCF_fibroblast of gingiva_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.03565 TAF13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04603 Kidney - Medulla GTEx Tissue Gene Expression Profiles 2023 1.0 5.0131 HOXC9 ChEA Transcription Factor Targets 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCE4 DepMap CRISPR Gene Dependency 1.0 2.44205 TUNAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46717 CTCF_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BLOC1S4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33878 Perturb_12333_KD_FOXM1_SRP200698 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.47759 CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 0.970008 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 1.45396 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.31189 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.57406 orbital frontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.04209 NCIH1838 CCLE Cell Line Gene CNV Profiles 1.0 1.70822 ALG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.551 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 1.1233 MOLT-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null RNF2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18063 ZNF692 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.5632 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.65804 CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fallopian tube GTEx Tissue Gene Expression Profiles 1.0 0.878081 GTEX-S7SE-0011-R8A-SM-2XCDG GTEx Tissue Sample Gene Expression Profiles 1.0 0.88871 SNUC4 DepMap CRISPR Gene Dependency 1.0 2.65355 FBXO21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55566 H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.949211 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE124471,GSE124488_2_v_3_lats1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04004 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.46782 Temporal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.845166 GTEX-R55D-1426-SM-48FEN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.836736 Perturb_2336_KD_WBP11_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.34425 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13216 GTEX-T5JC-0426-SM-32PLO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21415 GTEX-WRHU-0006-SM-3MJF6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.871863 GTEX-UPJH-0526-SM-4IHK8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.94702 Perturb_1371_KD_IGF2BP2_SRP252209 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.49817 CALR_KO_GDS3680_149_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE89057_0_v_1_sox5_human RummaGEO Gene Perturbation Signatures -1.0 null CTCF_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49168 HS 675.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.977719 PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8 Rummagene Transcription Factor Associations 2026 1.0 null HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1343 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-IKZF1_IKZF1 Rummagene Transcription Factor Associations 2026 1.0 null HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.939742 E2F6 ENCODE Transcription Factor Targets 1.0 null GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles 1.0 2.14561 MT-ATP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16865 lateral preoptic nucleus, PO2 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.42769 medial part of r1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16616 JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14827 GTEX-Q2AG-0011-R5A-SM-2HMJH GTEx Tissue Sample Gene Expression Profiles 1.0 0.86938 RAD21_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-1626-SM-32PLS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39901 H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RAD21_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3859_KD_DDR2_SRP333146 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.35515 CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-U8XE-0426-SM-3DB91 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04202 CTCF_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.78823 intermediate stratum of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03438 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 49.5481 CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12864_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null reticular complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14335 layer 6 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03737 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41988 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.833608 EMP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88799 GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.981968 Orbital area, medial part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14672 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.78974 DYNLRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03039 CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.968467 Perturb_4188_KO_Rest_SRP234983 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.48254 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.11524 FANCE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.622 OAW28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.75645 Secondary motor area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01604 NCIH1975 CCLE Cell Line Gene CNV Profiles 1.0 1.50189 rhombomere 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56593 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.956143 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79578 TRIM52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61306 GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02809 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.75491 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-2226-SM-47JYQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06353 Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79101 mantle zone of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16616 ORAI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35839 non-membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 PAX2 JASPAR Predicted Transcription Factor Targets 1.0 null 496100313_HIP_possible Alzheimer's disease_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.02595 Perturb_7329_OE_MOV10_SRP120600 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.77833 GSE119978,GSE180930_6_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null TMEM179B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05048 GTEX-X638-0005-SM-47JX6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59293 ES-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBEW-1326-SM-4AT63 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28637 769-P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.85476 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.929706 CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1006_KO_Bcl9l/Bcl9_SRP045828 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.50693 TUBA4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.4928 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7038 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.183645 POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31933 GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.71525 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.295 GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16697 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25645 PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null IKZF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30192 superficial stratum of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13976 GTEX-TKQ2-0006-SM-33HBH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.856945 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49452 TE4 CCLE Cell Line Gene CNV Profiles 1.0 1.55078 DNAJA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99675 OE33 COSMIC Cell Line Gene Mutation Profiles 1.0 null SKN3 DepMap CRISPR Gene Dependency 1.0 4.41881 GSE173810_4_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.472 CLTC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36805 cerebellar cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.993726 RAD21_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.0342 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.896147 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0886 RAD21_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_cardiac muscle cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5 ENCODE Transcription Factor Targets 1.0 null GTEX-OIZG-1026-SM-3LK5X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.975801 AGS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00549 SARNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59848 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12778_KO_C9orf72_SRP301422 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.39917 496100393_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.0547 MHH-ES-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.54386 CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.987504 RFWD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32484 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.852879 H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Spinal nucleus of the trigeminal, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12686 H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MPHOSPH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.34697 GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55289 SNU-16 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.719 pituitary GTEx Tissue Gene Expression Profiles 1.0 1.21075 GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles 1.0 1.52574 GTEX-T6MO-0626-SM-4DM6P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.987371 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32355 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.050023 Perturb_18444_KD_YAP1/WWTR1/STING1_SRP303519 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.2015 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.996232 Perturb_16923_KO_miR26a1/miR26a2/miR26b_SRP216065 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 15.3496 Brain stem TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CTCF_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COX5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40083 RAD21 ENCODE Transcription Factor Targets 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null Perturb_12396_KO_KRAS_SRP344246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.04988 Agranular insular area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2949 CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null PDCD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71534 Perturb_6735_KD_EHMT2_SRP043290 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.30836 GSE190316,GSE190324_6_v_9_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null nuclear lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GDAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06903 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pancreas GTEx Tissue Gene Expression Profiles -1.0 -0.862762 ES8 DepMap CRISPR Gene Dependency 1.0 7.32826 EP300 ENCODE Transcription Factor Targets 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.36553 GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37589 CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytosol COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0673 pontomedullary hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21888 NCI-H1793 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null chr14_59678015_C_A_b38 GTEx eQTL 2025 1.0 2.46691 D-566MG COSMIC Cell Line Gene Mutation Profiles 1.0 null EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1545 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.948383 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CKS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55554 GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.966806 sublayer 6a of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06346 GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.924906 496100582_HIP_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.17973 Perturb_9497_KO_Bscl2_SRP345421 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.33526 GTEX-Q2AH-1826-SM-2S1Q2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.948753 RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2456 FOXM1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.1497 DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8054 NEFL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85833 Perturb_9835_KD_GCN2_SRP248465 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.79482 horizontal nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00352 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60699 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.40898 dorsolateral prefrontal cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.963876 CTCFL_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Large_Intestine-intestinal crypt stem cell Tabula Sapiens Gene-Cell Associations 1.0 0.380084 SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7895 H3K27me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Frontal pole, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21773 GTEX-PVOW-0011-R3A-SM-32PKX GTEx Tissue Sample Gene Expression Profiles 1.0 0.850466 Perturb_2325_KD_SF3A1_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.02602 anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.983207 H3K14ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.09586 GTEX-P4QR-0726-SM-2I5GO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869 SP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25139 RIMOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34209 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.32617 Tegmental reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62102 H3K27me3_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BL5659 (ANKZF1) NURSA Protein Complexes 1.0 null GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-0011-R8A-SM-4E3II GTEx Tissue Sample Gene Expression Profiles 1.0 0.86339 SW1710 CCLE Cell Line Gene CNV Profiles -1.0 -1.54423 BZW1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29189 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837205 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.894504 NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.04845 HSPB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11944 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21216 preopto-hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04513 TMEM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08954 GTEX-NL3H-0011-R2a-SM-2I3GG GTEx Tissue Sample Gene Expression Profiles 1.0 0.894564 rhombomere 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.0051 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17726 SBC5_LUNG CCLE Cell Line Proteomics 1.0 2.12806 CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PDS5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20947 GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.69167 GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58784 H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46049 NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.985869 TCF12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1556 769P CCLE Cell Line Gene CNV Profiles -1.0 -1.49 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null organelle part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.37907 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null MAFK_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87371 r4 part of descending trigeminal sensory nucleus, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79578 RKO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.847851 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.60817 brain GTEx Tissue Gene Expression Profiles 1.0 2.00274 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1901 CTCF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12937_KO_SPI1_SRP342114 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.57426 GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 0.945802 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.103 Perturb_4316_KO_Ror2_SRP292420 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1838 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71704 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00289 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04004 SRSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41528 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TPRKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83407 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05083 GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55106 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.50119 GTEX-T6MN-0011-R11A-SM-32QOX GTEx Tissue Sample Gene Expression Profiles 1.0 2.76304 H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22304 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0659 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.72011 SW1088 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.94556 RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.7278 SKP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65348 POLR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14782 intermediate stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16616 superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12258 PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null LRP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82248 LRRC40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41701 GTEX-XLM4-0011-R2B-SM-4AT5Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.935185 type ii diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.837193 amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12375 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-0011-R1A-SM-32PL6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02275 BANP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2063 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19204 Agranular insular area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00644 PPP2R5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11056 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.986666 neurological GAD High Level Gene-Disease Associations 1.0 0.293278 COLO680N DepMap CRISPR Gene Dependency 1.0 4.18725 H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.80313 Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74811 SF172 CCLE Cell Line Gene CNV Profiles 1.0 1.38702 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25868 SLC29A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41472 GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 GTEX-XMD3-0006-SM-4AT5X GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 Genital Diseases, Female CTD Gene-Disease Associations 1.0 1.16001 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14709 LAMA-84 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.07023 intracellular organelle part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21254 GTEX-QEL4-1326-SM-447AD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.865614 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.114728 Perturb_5004_KO_Rinf_SRP200002 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.4508 CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAPRIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16458 H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FSTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08894 BC-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.82832 JHUEM2_ENDOMETRIUM CCLE Cell Line Proteomics 1.0 2.70628 RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TML8-1526-SM-4DXUX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19033 GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6473 K029AX CCLE Cell Line Gene CNV Profiles -1.0 -1.57836 MAP4K5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27816 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 APAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.57162 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null LKAAEAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50514 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18255 prethalamic (p3) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.45391 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26308 GTEX-WZTO-2826-SM-3NM8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.97686 CASP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78061 primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.80073 CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLF13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.5471 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.04207 CAL-12T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52688 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.21021 WDR59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02021 DG-75 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.30498 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.40787 cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 JUND ENCODE Transcription Factor Targets 1.0 null KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86077 dorsomedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06755 GTEX-WHSB-2026-SM-3LK6H GTEx Tissue Sample Gene Expression Profiles 1.0 0.826003 RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35611 GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13976 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HROB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46146 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM131L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65995 HEYA8_OVARY CCLE Cell Line Proteomics 1.0 2.17838 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19954 Collagen trimer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.742 lateral part of r2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89059 GSE171292_6_v_0_ehhadh_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -2.19331 abnormality of cardiac morphology GWASdb SNP-Phenotype Associations 1.0 0.774448 GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.00447 GSE215086_1_v_6_batf_human RummaGEO Gene Perturbation Signatures -1.0 null TOP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07713 H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.793 r4 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84277 CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12874_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42843 NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02974 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEATR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.88001 JHU-029 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PVOW-1626-SM-48TC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0132 CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GFI1_KO_GDS4204_147_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Hippocampus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00576 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMK1-0326-SM-4B652 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.87175 CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.62148 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55C-0826-SM-48FCL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.859878 CACHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37119 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.82744 H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TRIM62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38826 EOLA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02583 mantle zone of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84277 STAT1 ENCODE Transcription Factor Targets 1.0 null intermediate stratum of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71643 RKO-E6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.852879 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.828453 PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null eGFP-FOS_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_11971_KO_SUZ12_SRP327198 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.19187 abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.097948 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.947522 RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1811 GTEX-WL46-0011-R11A-SM-3MJFT GTEx Tissue Sample Gene Expression Profiles 1.0 1.85962 RAVER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98727 PAK1IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97385 cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37208 PIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40797 hsa-miR-499-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 1.61192 CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0805 SNX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35984 BATF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03828 RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 4.50386 GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.13273 MFE296 DepMap CRISPR Gene Dependency 1.0 2.72472 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-1626-SM-2HMKK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.888626 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE183271_1_v_0_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null CDX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16858 SLR24 CCLE Cell Line Gene CNV Profiles -1.0 -1.33392 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12867_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.920402 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null XRCC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31217 mantle zone of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12686 GTEX-S7SE-0011-R11A-SM-2XCDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.70216 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CTCF_CTCF Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F2 ENCODE Transcription Factor Targets 1.0 null POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WM1552C Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.35376 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.859764 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20511 PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA Rummagene Transcription Factor Associations 2026 1.0 null GSE145249_0_v_2_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null U266B1 CCLE Cell Line Gene CNV Profiles -1.0 -2.50222 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NKX3-2 JASPAR Predicted Transcription Factor Targets 1.0 null Angioid streaks DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.362 MED31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38419 nucleolus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 TE-6 COSMIC Cell Line Gene CNV Profiles 1.0 2.12225 GTEX-QV44-0826-SM-2S1RG GTEx Tissue Sample Gene Expression Profiles 1.0 1.06627 Perturb_7474_KD_Chtopl_SRP144331 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.4379 GTEX-QMR6-0011-R2A-SM-32PKV GTEx Tissue Sample Gene Expression Profiles 1.0 1.0974 Perturb_11960_KD_RAD6B_SRP258673 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.30236 intracellular COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 prethalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18108 RPRD1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50274 posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.52939 GSE219195_1_v_5_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874582 WARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7417 GSE184087_0_v_1_tert_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.319221 Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43261 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57309 Perturb_2318_KD_PRPF8_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.77556 P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.01665 RRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5854 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KMT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96041 496100604_HIP_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.10977 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_16849_KO_Hnrnph1_SRP068520 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55701 GSE165647_5_v_1_cry2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE141328_3_v_2_rock2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null amygdaloid complex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.95807 GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86318 CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.01646 Taenia tecta, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64268 CTCF_GM12864_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VUSG-2626-SM-4KKZI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12706 NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1417 COSMIC Cell Line Gene CNV Profiles -1.0 -3.32901 ZNF143 ENCODE Transcription Factor Targets 1.0 null GTEX-T5JC-2326-SM-32PMR GTEx Tissue Sample Gene Expression Profiles 1.0 1.79317 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19475 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null DUSP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.20566 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01941 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.841677 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2308_KD_DHX8_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.12538 superficial stratum of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17886 striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07736 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34142 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -3.82124 SNUC2A_LARGE_INTESTINE CCLE Cell Line Proteomics 1.0 2.01711 RAD21-21589869-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ2-0426-SM-4DXUO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49472 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.24615 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOTO-0011-R8A-SM-4B65J GTEx Tissue Sample Gene Expression Profiles 1.0 0.846291 MOB3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30314 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KLHL34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16695 Perturb_694_KD_SREBP2_SRP064735 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.51184 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null pregeniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.67665 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14849 Attention deficit hyperactivity disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.812 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08415 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null SCAF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21411 TMEM143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0121