association dataset threshold value standardized value HDAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61598 GSE168797_1_v_5_cannabidiol_human RummaGEO Drug Perturbation Signatures 1.0 null Yunis-Varon syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.365 Ebf4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.935 EDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39992 C8orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77473 GSE193993_0_v_7_sstr2_human RummaGEO Gene Perturbation Signatures 1.0 null PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null GSE202434,GSE202438_12_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3213 GSE206226_2_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null TXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67179 GSE226770_1_v_6_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null GLG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81605 ZNF875 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08366 chr1_162854763_G_A_b38 GTEx eQTL 2025 1.0 1.9448 NAGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98583 AGPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52159 GSE233679_14_v_9_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE211983_1_v_2_nicotine_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE169334,GSE169336_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null ZBTB17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34667 PMC9170110-pgen.1010161.s047.xlsx-DBP_DEP-nearestGene_DBP Rummagene Transcription Factor Associations 2026 1.0 null MRPL30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55379 HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.039 GSE174701_5_v_2_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null ZNF100 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91008 ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6027 NANOS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56682 MTPAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71141 PAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02394 496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.27736 CACNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86941 SMARCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35456 PMC9341507-supp_gr.266924.120_Supplemental_Table_S4.xlsx-A_Jurkat_essential-MYB_MYB Rummagene Transcription Factor Associations 2026 1.0 null VWA5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81596 BAZ1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7048 GSE233679_14_v_8_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.1984 Response to fenofibrate (triglyceride levels) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 NRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03155 SLC2A14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9788 GSE202603_3_v_2_bhlhe40_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE192870_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE178532_2_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null TP63 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9049 GSE238018_3_v_5_mxra8_human RummaGEO Gene Perturbation Signatures 1.0 null NPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68224 RAB22A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07979 H2BC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79144 GSE148200_0_v_5_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC Rummagene Transcription Factor Associations 2026 1.0 null GSE210580_0_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0 GSE112962,GSE112963_2_v_1_ddx5_human RummaGEO Gene Perturbation Signatures 1.0 null KMT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31571 PMC5066615-supp_30.18.2093_Supplemental_Table_S1.xlsx-GR_YBX1_and_HRSP1_down_1_5_fold-Unnamed_1_YBX1 Rummagene Transcription Factor Associations 2026 1.0 null SPRED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54638 GSE174701_1_v_2_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null DLX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98905 RBM15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30269 ITPRIPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07869 GSE143316_0_v_6_somatostatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE79663_2_v_0_tcf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE195503_3_v_0_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null ZFP57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90916 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.7489 ACP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06333 GSE202434,GSE202438_8_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE157960_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE119978,GSE180930_0_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE214514_1_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE210580_3_v_2_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ACBD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61299 MGAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36072 GSE220806_0_v_3_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null B3GNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7156 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.851 PRKAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97211 GSE202434,GSE202438_2_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null ATAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69133 PMC6802116-41467_2019_12517_MOESM5_ESM.xlsx-Sheet1-D9_8_GNF2-SERPINB5_CENPX Rummagene Transcription Factor Associations 2026 1.0 null BOK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95923 GSE157960_0_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null MTRR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6867 ATP6V0A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52663 DBNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35873 GSE102505_6_v_0_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5855 RAB17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93004 MND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63819 496100574_HIP_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.38569 XPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39745 YTHDF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65009 GSE128232,GSE128233_1_v_0_phf2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE143316_0_v_5_somatostatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null MRPS23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88304 Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 USP49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24793 496100470_HIP_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.57192 GSE182854_2_v_0_sirt1_human RummaGEO Gene Perturbation Signatures -1.0 null TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4349 GSE245407,GSE245412_0_v_1_smurf1_human RummaGEO Gene Perturbation Signatures -1.0 null PIGC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26374 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.1679 GSE126345_7_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null ECE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62606 GSE250089_0_v_3_epcam_human RummaGEO Gene Perturbation Signatures -1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null MYCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25429 USP44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92254 PLK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1215 FOXK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73934 Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.9565 ARPC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42862 AASDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95252 PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null DIS3L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22303 Type I terminal bouton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.903 ZNF629 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4542 PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null ZNF559 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51874 ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2119 MTMR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62397 GSE148200_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF430 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50475 PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null GSE145476_2_v_0_hopx_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE119978,GSE180930_6_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Almonertinib (hydrochloride)_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0171725 ZFHX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53867 Muscle tendon junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.651 GSE164874_5_v_10_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE141328_1_v_0_rock2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SLC66A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92467 UNC13D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96322 Flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.935 GSE133691_1_v_3_lgr5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE92589_0_v_1_sirolimus_mouse RummaGEO Drug Perturbation Signatures -1.0 null PAX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0977 GSE137177_2_v_0_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null TPBG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59531 UQCRQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78244 ENGASE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46454 PRDM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70192 CLDN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27842 PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null GSE65617_5_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE198971_0_v_2_ncor2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NRN1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66505 ERCC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02729 ARL4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56362 GSE213228_4_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE229978_4_v_1_morphine_mouse RummaGEO Drug Perturbation Signatures -1.0 null FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.593 H2BC15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07314 GSE147876,GSE147877_4_v_7_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE184087_4_v_5_tert_human RummaGEO Gene Perturbation Signatures -1.0 null Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.6474 MOSPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08974 DFFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03951 GSE239436,GSE239441_0_v_1_keap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE175787_13_v_0_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null 496100392_HIP_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.65966 HS2ST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69716 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.6796 WDR24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66032 496100635_HIP_dementia_TBI_77_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.21688 SLC25A19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27732 CCDC82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20412 PMC10311050-mmc2.pdf-62-MAZ_MAZ Rummagene Transcription Factor Associations 2026 1.0 null FHL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63592 GSE166317_3_v_0_j147_mouse RummaGEO Drug Perturbation Signatures 1.0 null FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4865 PARP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58461 GSE214823,GSE214824_6_v_2_crtc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PTOV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82067 PAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8479 Melanoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.56 SDHAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57387 GSE136622_6_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE202434,GSE202438_4_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE206400_3_v_4_nusinersen_mouse RummaGEO Drug Perturbation Signatures 1.0 null HOXC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97333 TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3269 ROCK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28775 PMC10933424-41420_2024_1903_MOESM1_ESM.pdf-2-PRDM13_PRDM13 Rummagene Transcription Factor Associations 2026 1.0 null NEUROD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87815 GSE175787_13_v_7_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null HNF4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92223 GSE193402_0_v_1_imatinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE171572_0_v_2_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null 496100503_HIP_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00907 UBN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66564 ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0942 NOS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69046 GSE211983_0_v_2_nicotine_mouse RummaGEO Drug Perturbation Signatures 1.0 null TSHZ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83656 AURKC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49954 PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null TRMT10C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57922 FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9435 LYN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74192 496100417_HIP_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.63405 THAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7665 GSE135352_2_v_3_napabucasin_human RummaGEO Drug Perturbation Signatures 1.0 null FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5279 ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0068 RPRD1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33586 Cannabis abuse DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 ANP32A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80614 Daytime nap GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.652288 GSE211128_9_v_6_angptl4_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF394 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49514 POU6F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18139 GSE180185_9_v_10_setbp1_human RummaGEO Gene Perturbation Signatures 1.0 null PIANP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17717 IL17RB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62731 SLC39A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34239 GNAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20104 PMC5799303-41598_2018_19627_MOESM3_ESM.xlsx-S12_THP1_AT_pFDR_0_3-Unnamed_2_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null Sebum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.521 Pars tuberalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.875 APLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76981 GSE148252_1_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null NANOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10087 L1TD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13293 CTNNAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45041 HIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51433 TARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06046 GSE202825_2_v_1_ano1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE165678_4_v_5_stat5a_human RummaGEO Gene Perturbation Signatures 1.0 null Calcaneal bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.598 PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4 Rummagene Transcription Factor Associations 2026 1.0 null GSE210580_4_v_12_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE242083,GSE242098_2_v_1_med1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE256181_2_v_3_etv2_human RummaGEO Gene Perturbation Signatures -1.0 null FAM86B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43507 GSE210580_3_v_11_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null MICALL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2718 CRABP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89782 SERPINF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.33778 LMNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52991 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9859 DNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95115 GGCX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84393 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA2_FOXA2 Rummagene Transcription Factor Associations 2026 1.0 null TRIM56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86008 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 82.1725 NDUFB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40595 GSE236280_0_v_1_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null ACAD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3749 GSE178532_2_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4761 FOXP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3363 Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 63.1775 Methylthiouracil_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0129138 CTDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15524 GSE126345_2_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Zic1::Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.4846 CUL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44457 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1361 HES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7924 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5856 DAGLB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70395 WDR59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40088 UBE2O CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8098 ZNF667 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9755 GSE145628,GSE145629_1_v_0_myrf_human RummaGEO Gene Perturbation Signatures -1.0 null LGALSL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57105 Sox5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.4113 RAD54B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39053 GSE174522_1_v_0_spp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE157904_0_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE172458_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE157894_2_v_0_cystine_human RummaGEO Drug Perturbation Signatures -1.0 null Hallucinogen dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.446 TRIM47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21098 CDK5RAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89486 TRMT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2267 PAFAH1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82857 HEY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75274 RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3333 ZNF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18285 CPXCR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95052 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.9153 C3orf14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34945 FOXD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.1418 GSE195503_1_v_0_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE126621,GSE126920_1_v_0_dppa4_mouse RummaGEO Gene Perturbation Signatures -1.0 null AMER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18516 INTS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69022 MFAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9641 GMCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21193 GSE148200_4_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.4586 FAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97908 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.361 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8289 C10orf105 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30867 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9069 GSE135352_0_v_4_napabucasin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE135352_6_v_4_napabucasin_human RummaGEO Drug Perturbation Signatures 1.0 null P3H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45626 GSE210580_0_v_11_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null POU3F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45436 GSE77178_2_v_3_ccnd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SPINT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3235 STRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89266 CORO1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75024 Vinblastine (sulfate)_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0159156 ZNF783 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46874 METTL21A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2918 DGKK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92534 GSE195503_1_v_2_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE173262_2_v_0_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6572 SIRT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1998 C1orf52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51266 GSE210885_2_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null CCDC28A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14572 Cocaine dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.243 ACTR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32837 CARD19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49425 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.127 RPL29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15908 FAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45107 GSE218580_1_v_3_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC7725876-Table_2.xls-Sheet1-Table_2_v1_DEGs_in_the_BESC_were_treated_with_LPS_compared_with_PBS_control_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6682 ELP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69778 GSE217452_3_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null GSE168697_0_v_1_wdr6_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE185163_3_v_1_clic4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cells - EBV-transformed lymphocytes GTEx Tissue Gene Expression Profiles 2023 1.0 2.16681 PRDM13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38787 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0643 496100480_HIP_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.48526 PMC8299217-mmc4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1 Rummagene Transcription Factor Associations 2026 1.0 null PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521 Rummagene Transcription Factor Associations 2026 1.0 null GSE184902_4_v_0_adipor1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF276 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92773 RIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18347 IGFBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82788 GSE79291_1_v_2_streptozotocin_mouse RummaGEO Drug Perturbation Signatures -1.0 null DAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53379 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.5484 GSE166317_2_v_0_j147_mouse RummaGEO Drug Perturbation Signatures 1.0 null FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5241 GALNT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84871 DIS3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50492 MCOLN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07621 BICRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49341 N6AMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50084 GSE128076_1_v_3_doxycycline_human RummaGEO Drug Perturbation Signatures 1.0 null FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.019 GSE175787_13_v_2_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null PLAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96181 GSE119978,GSE180930_3_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE246461,GSE246463_5_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOXG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1499 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7857 VIPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18466 GSE101239_4_v_1_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null CMIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16478 ZNF564 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84123 DMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51666 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5919 FKBP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02496 NDUFAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7873 KDM3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52728 ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9882 496100645_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.65582 GSE129370_0_v_1_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null MED25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28584 PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null GSE140092_0_v_1_socs3_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOXN3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4228 GSE210580_4_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE213632_3_v_6_acod1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BMI x environmental factors (excluding physical activity) interaction GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.630103 HTRA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28086 GSE225762_1_v_0_pcmt1_human RummaGEO Gene Perturbation Signatures -1.0 null LGI4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47105 Perindopril (erbumine)_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0082198 ANO9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43476 GSE166536_1_v_2_docetaxel_mouse RummaGEO Drug Perturbation Signatures 1.0 null CFAP68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57331 SETX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53163 GSE213228_2_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC Rummagene Transcription Factor Associations 2026 1.0 null JAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61152 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null GSE195559_8_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE195559_6_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE128076_1_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures 1.0 null GSE173262_6_v_0_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null SECISBP2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50116 RBPJ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6757 GSE77108_5_v_9_saha_human RummaGEO Drug Perturbation Signatures 1.0 null GSE142684_4_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null SRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69066 GSE119978,GSE180930_2_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null OXER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71094 GSE119978,GSE180930_0_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null PCNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43415 FAM217B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48737 Substance dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.456 PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null NPY1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05518 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4404 APCDD1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0901 PACS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40676 EMILIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85458 GSE181821_1_v_3_mov10_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZKSCAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84941 BCL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11524 ABL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20406 TPM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86611 496100401_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.44511 DNAJC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24412 GSE168807_0_v_7_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null ACIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91029 GSE212074_0_v_1_pus1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE153836_11_v_2_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5845 PGRMC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65435 Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.2228 FBXO34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93319 CACYBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00997 ZNF827 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75965 BET1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37801 TMEM125 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.896 GSE110038,GSE133995_3_v_0_hic1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CENPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1632 Normal pressure hydrocephalus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.449 GSE213228_1_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE233679_6_v_2_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null ESRRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.41459 PTPMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35432 AKR1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28876 Perirenal adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.767 CCDC93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.72687 GSE219103,GSE219104_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE73561,GSE73563_0_v_1_mef2c_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE205163,GSE205164_2_v_4_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.2695 GSE232631_0_v_2_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ATL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.35267 GSE232558_0_v_1_fbxl12_human RummaGEO Gene Perturbation Signatures -1.0 null GSE204784,GSE204787_1_v_0_tfcp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2 Rummagene Transcription Factor Associations 2026 1.0 null GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE148252_7_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9151 GSE137177_1_v_0_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5294 TRIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48413 ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.7873 ENSG00000286190 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16144 PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null ZFP92 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23625 GSE81803,GSE81912_0_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-B_FUS-DDIT3-eGFP_vs_WT-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null BRSK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35871 GSE174701_5_v_6_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null Ewing's sarcoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.728 GSE202434,GSE202438_9_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE235701,GSE261434_2_v_3_enasidenib_human RummaGEO Drug Perturbation Signatures 1.0 null Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0058 DHFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73829 PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Down_MSC Rummagene Transcription Factor Associations 2026 1.0 null SLC35A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23597 NUP188 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68355 ATIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56334 PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null RAB5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48927 GSE101112_6_v_4_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null TMEM167A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56988 CTSL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23393 GSE205070_1_v_4_mertk_mouse RummaGEO Gene Perturbation Signatures 1.0 null Busulfan_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0174412 MEF2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21937 RAB5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18609 HIVEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33027 Testis GTEx Tissue Gene Expression Profiles 2023 1.0 4.94917 PMC5735185-41467_2017_1200_MOESM4_ESM.xlsx-Table_S1-Choi_et_al_2016_DUX4_up-regulated_targets_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null GABPB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82939 GSE210580_4_v_6_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE231799_2_v_1_nfkbie_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE77108_6_v_1_saha_human RummaGEO Drug Perturbation Signatures -1.0 null YWHAG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66729 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.9102 NECTIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50243 PLEK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44204 PMC5799303-41598_2018_19627_MOESM3_ESM.xlsx-S12_THP1_AT_pFDR_0_3-Unnamed_1_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null TMEM134 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30439 Nicotine dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.203 GSE217132_0_v_1_pfkfb4_human RummaGEO Gene Perturbation Signatures -1.0 null CHST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65147 GSE77108_8_v_9_saha_human RummaGEO Drug Perturbation Signatures 1.0 null RPUSD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13238 olaparib_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0198074 TSPAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97914 STX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20375 ZBTB44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83191 LDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27646 C11orf71 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18014 GSE81803,GSE81912_4_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null KLF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41124 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7645 GSE218819_3_v_4_kdm5b_human RummaGEO Gene Perturbation Signatures 1.0 null GSE239541_8_v_4_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MEST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44312 NME3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59519 ETV7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.04 Gilles de la Tourette syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.072 Cannabis dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.447 GSE142588_2_v_1_cinobufagin_human RummaGEO Drug Perturbation Signatures -1.0 null ACSBG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03525 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7938 C21orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30445 CHRDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24296 GSE226584,GSE226589_1_v_0_ezh2_human RummaGEO Gene Perturbation Signatures 1.0 null Gefitinib_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0177417 PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null SBK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36211 GSE119978,GSE180930_6_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE202434,GSE202438_3_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC Rummagene Transcription Factor Associations 2026 1.0 null ZNF862 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.118 GSE248858_1_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null SELENOV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8657 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2362 CUEDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17697 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.465 MLLT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.09952 PARP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61415 GSE178340_7_v_3_carfilzomib_human RummaGEO Drug Perturbation Signatures -1.0 null FMNL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91399 GSE175787_13_v_6_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null BLOC1S2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3038 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-480-ENSG00000158773_USF1 Rummagene Transcription Factor Associations 2026 1.0 null TIMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21922 DCP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93483 GSE191021_1_v_0_nono_human RummaGEO Gene Perturbation Signatures -1.0 null UNC5CL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55219 ONECUT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07625 ZFYVE26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.452 GSE203308_4_v_10_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE199034_1_v_0_pirfenidone_mouse RummaGEO Drug Perturbation Signatures -1.0 null TSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02604 GSE195568_3_v_10_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE187006_0_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF250 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75837 PLEKHG4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11155 ATP6V1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16424 ZNF835 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37121 TOX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2358 BBLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85485 PJVK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61496 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null GSE220806_1_v_3_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF483 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16355 FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.4015 GSE119978,GSE180930_2_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ESCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5642 TRIM16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01786 GSE101336_1_v_2_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null H2AC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52059 TCEAL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51415 TMTC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07501 FOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4576 FGD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32226 GSE205163,GSE205164_9_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null GSE145323,GSE145324_3_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE164521_0_v_1_nitric oxide_mouse RummaGEO Drug Perturbation Signatures 1.0 null ZMYM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43939 GSE81803,GSE81912_0_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5423 H3C11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14025 PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null ZGPAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37265 TNFRSF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28211 CBFA2T2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12118 LMBR1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28878 GSE234340_9_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0921 TRUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89187 C19orf47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3997 GSE65617_5_v_1_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null IFI16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87871 MIXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31527 GSE192870_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null USP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73945 Subsynaptic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.903 PRDX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4375 MAP3K10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28942 TDRD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94009 MLH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41677 SH2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55 ZBTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49129 GABARAPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93431 GSE232836_2_v_6_morphine_mouse RummaGEO Drug Perturbation Signatures -1.0 null FADS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72995 ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.042 PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null substance-related disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.277 ZNRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50761 GSE217115_3_v_5_alectinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null Alcohol dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.345 GSE125211_0_v_1_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null ZMAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22907 DMRTA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6174 HOXC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1613 IPO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82304 GSE175787_13_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE94814_2_v_3_reck_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-31-USF1_USF1 Rummagene Transcription Factor Associations 2026 1.0 null HCST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16578 ONECUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76787 GSE136622_7_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE231799_3_v_4_nfkbie_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF691 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42096 ZFPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51232 NKIRAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79763 PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null GSE203308_15_v_10_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BEND6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39567 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2443 GSE218580_1_v_5_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.5833 WAC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10158 Tic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 GNPTAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64582 PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR Rummagene Transcription Factor Associations 2026 1.0 null NKX2-8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79801 TMSB15A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01922 PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR Rummagene Transcription Factor Associations 2026 1.0 null FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4618 ATPSCKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91256 GSE203308_1_v_10_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27732 TBX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17671 CACNB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78769 GSE163297_0_v_2_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE210870_0_v_2_snai1_human RummaGEO Gene Perturbation Signatures -1.0 null TALDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86495 GSE184902_4_v_0_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null SPSB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07183 SESN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56921 GSE119978,GSE180930_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Brain - Cerebellum GTEx Tissue Gene Expression Profiles 2023 1.0 3.98462 RRAGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36172 Pars distalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.896 NISCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53228 GSE202434,GSE202438_7_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3499 PMC6063960-41598_2018_29472_MOESM5_ESM.xlsx-lightcyan_module_HF-DMRTB1_DMRTB1 Rummagene Transcription Factor Associations 2026 1.0 null Drug dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.02 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7635 GSE211983_1_v_3_nicotine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Venous endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.502 GSE77108_6_v_7_saha_human RummaGEO Drug Perturbation Signatures -1.0 null RD-ES cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.906 GSE226770_1_v_0_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null GSE238018_1_v_0_mxra8_human RummaGEO Gene Perturbation Signatures -1.0 null TFAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32401 GSE178340_7_v_9_carfilzomib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE235701,GSE261434_0_v_3_enasidenib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE205163,GSE205164_5_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null SCARA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80312 H4C5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.57907 GPR25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34926 SDHAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79703 ACTR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54897 GSE210580_4_v_1_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null ELOA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96876 GSE165647_2_v_7_cry2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC8656035-40001_2021_613_MOESM2_ESM.docx-46-ARNT_ARNT Rummagene Transcription Factor Associations 2026 1.0 null POU2F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88771 SUMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43279 METTL25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36561 GSE195514_0_v_1_stk25_human RummaGEO Gene Perturbation Signatures 1.0 null GSE148252_1_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE174418,GSE174421_2_v_3_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null FAM199X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16893 Kmp TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.678 ETV5::HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3252 Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.4723 GSE117643_1_v_0_irx5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE231799_2_v_4_nfkbie_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE77108_3_v_7_saha_human RummaGEO Drug Perturbation Signatures -1.0 null MYBL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1472 GSE148200_0_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null ZSCAN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92109 FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0602 496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08043 GSE234340_1_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE240030,GSE252532_0_v_2_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null GSE164306_5_v_0_tsc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ARPIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95741 GSE202434,GSE202438_10_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null RARA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88083 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.4765 GSE101112_0_v_4_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE148252_7_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_3_AR Rummagene Transcription Factor Associations 2026 1.0 null FICD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52566 FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8287 CHD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06491 GSE238018_1_v_4_mxra8_human RummaGEO Gene Perturbation Signatures -1.0 null FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.7397 TMEM81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32751 GSE233679_5_v_15_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null Lopinavir_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0201425 GSE146840,GSE146842_0_v_2_qrich1_human RummaGEO Gene Perturbation Signatures 1.0 null PRMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12756 GSE186440,GSE186443_1_v_5_daxx_human RummaGEO Gene Perturbation Signatures -1.0 null IL17RD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15266 CALCOCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39741 GSE118816_0_v_3_myo1c_human RummaGEO Gene Perturbation Signatures 1.0 null GSE210580_0_v_2_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null LRPPRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98526 GSE175787_13_v_10_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE213632_1_v_6_acod1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX21_SOX21 Rummagene Transcription Factor Associations 2026 1.0 null MYO1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85119 FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4223 Vesicle COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.532 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.241 Ewing's sarcoma family tumor cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.708 GSE135352_6_v_3_napabucasin_human RummaGEO Drug Perturbation Signatures 1.0 null TRIM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14756 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null GSE209601_2_v_3_mef2a_human RummaGEO Gene Perturbation Signatures 1.0 null GSE233679_14_v_15_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE102505_6_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.9203 RRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13684 GSE205730,GSE205731_2_v_1_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null GSE205070_1_v_6_mertk_mouse RummaGEO Gene Perturbation Signatures 1.0 null SLC12A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16258 Sapling TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.123 DYRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15694 Rge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.737 GSE157894_1_v_0_cystine_human RummaGEO Drug Perturbation Signatures 1.0 null Set3 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.1 RXYLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92334 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1601 TMC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21365 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SRF_SRF Rummagene Transcription Factor Associations 2026 1.0 null GSE135352_2_v_4_napabucasin_human RummaGEO Drug Perturbation Signatures 1.0 null Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.941 GSE141328_3_v_2_rock2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GARIN1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0548 SR cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.885 PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6 Rummagene Transcription Factor Associations 2026 1.0 null Tanycyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.554 GSE174701_1_v_6_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null PMC9437810-mmc6.xlsx-Sheet1-Table_S8_Significant_isoform_switches_unique_to_BE_LGD_TP53_WT_vs_BE_HGD_TP53_MUT_TP53 Rummagene Transcription Factor Associations 2026 1.0 null NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1931 ERICH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13721 PRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94588 Lef1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.4764 C16orf86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00585 PCYOX1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83569 ZFP69B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34106 LHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29919 CD200 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55404 GSE149760_0_v_1_elof1_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF701 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 71.743 GSE127970_1_v_0_ebf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 JUNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29946 SMAD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74283 GSE235701,GSE261434_0_v_1_enasidenib_human RummaGEO Drug Perturbation Signatures -1.0 null OLFML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4405 EMSY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53081 TBL1X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38313 SIRT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30091 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 48.4627 SRSF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11042 FAM98C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96323 GSE94814_1_v_0_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null SSBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9576 Distal myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.033 SCRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88138 ZNF322 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42377 Communicating hydrocephalus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.381 ELK1::HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7947 ZNF708 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64904 CCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56081 Pathological gambling DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.051 ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8376 GSE211128_3_v_6_angptl4_human RummaGEO Gene Perturbation Signatures -1.0 null MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7068 GSE210870_0_v_1_snai1_human RummaGEO Gene Perturbation Signatures -1.0 null SSTR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53084 KCTD21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57171 Colorectal cancer GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.504576 PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null PAX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17526 GSE233679_5_v_8_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC8285542-41467_2021_24656_MOESM4_ESM.xlsx-Sheet1-The_genes_positively_or_negatively_correlated_with_TP63_in_SCC_TP63 Rummagene Transcription Factor Associations 2026 1.0 null ARMC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98147 GABPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17793 AIRE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82072 PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null PCDHB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78783 ARID5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50364 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3062 GSE113734_3_v_0_qprt_human RummaGEO Gene Perturbation Signatures 1.0 null PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2 Rummagene Transcription Factor Associations 2026 1.0 null GSE185163_5_v_2_clic4_mouse RummaGEO Gene Perturbation Signatures 1.0 null NMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70284 Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6146 RHOH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19432 GSE228894_0_v_1_rnmt_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null APTO-253_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.00917913 PPP2R5E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06543 KEAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08859 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0461 PMC7899452-media-5.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1 Rummagene Transcription Factor Associations 2026 1.0 null YME1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25816 GSE216273,GSE216292_14_v_6_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null PLAUR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60212 CLPP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58101 SPATA5L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.569 TARBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57594 PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null OSBPL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00918 GSE216540_0_v_6_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null