association	dataset	threshold value	standardized value
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980165
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.923
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980165
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15380626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62294
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6315
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	2.59151
GF1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21386
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12059
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21371
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29636267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95015
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8064
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.898573
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43159427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4306
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8011
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47866
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21693
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.961817
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93668
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49075
BRD-K44664883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17967
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.966548
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833318
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11109_KO_Ppara_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.2098
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931172
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08182
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34585
BRD-K39153737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24408
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.4449
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965438
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5463
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897606
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218147
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.08
BRD-K24825509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67855
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10234
BRD-K29713418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15202
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.70241
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93355
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42865
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00863
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69226
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05055
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.39948
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96914
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028127
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89917
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13954
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.889154
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37152
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82423
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44537
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79235
GSE149124,GSE149128_3_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850913
BRD-K42964587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10816
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9446
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866853
BRD-K23440419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24346
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92393
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39519
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43903
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52455
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95051
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06559
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10155
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.874554
hsa-miR-624	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33612
BRD-K44759088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06388
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
furazolidone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54951
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7803
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5085
BRD-K10010414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1518
BRD-K81801123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74145
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893684
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824437
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207155
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5068
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.91222
Perturb_7575_KO_SF3B1_SRP342911	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.69581
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75689
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23465
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36423
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.905057
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5805
BRD-K28545166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47657
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861373
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.18575
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32353
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.942747
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6996
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19311
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CORL88	CCLE Cell Line Gene Expression Profiles	1.0	1.63724
TEAD4	ChEA Transcription Factor Targets	1.0	null
TTC549	DepMap CRISPR Gene Dependency	1.0	3.38324
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839929
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Psammoma body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958509
BRD-K84348716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80273
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.97172
BRD-K96491664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91331
AZ521	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64732
GSE147056_3_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55044152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56197
rosiglitazone_mus musculus_gpl1261_gds3798	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20334
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02633
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29456
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19724
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18343
BRD-K45799338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96278
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20669
Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW1353	CCLE Cell Line Gene Expression Profiles	1.0	2.13783
BRD-K00048155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31902
BRD-K72224143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.5613
Lung adenocarcinoma_LUAD_TCGA-78-7161-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.60272
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90139
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5207
GSE211286_7_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881036
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-461-ENSG00000127124_HIVEP3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64888
BRD-K24343201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54736
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930845
ATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04541
BRD-K90693562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19564
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979553
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42502
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34463
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.16766
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72586
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.4631
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.04093
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873328
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.12898
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62834
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09907
BRD-K89992188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5461
GSE248858_6_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968924
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0152
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35189
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907056
T84	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53262
TK10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10625
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65146
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21886
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23195
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22538
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44441
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01671
BRD-K90284572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13311
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13549
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30409
Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.10083
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11008
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47003
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6498
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.909124
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04756
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.39945
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56999
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08381
NCI-H929 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11558
GATA2_01_193	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.4413
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Protein phosphatase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
BRD-K44878051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05511
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19577
IOMMLEE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85122
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4154
stomach	HPA Tissue Protein Expression Profiles	1.0	0.733989
BRD-K24848743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01285
BRD-K74415279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03375
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29772
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865281
BRD-K69468381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1401
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37204
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0207
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6726
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.91582
Acral lentiginous melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03645
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48338
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30881
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39887
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25093
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908914
BRD-K97939219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11353
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998455
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22926
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32792
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06424
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6207925-CDEV-89-1839-s001.xlsx-Table_4_FDR_hits_ODD_H_ADHD-Unnamed_12_OSR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31799
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13295
NB1	DepMap CRISPR Gene Dependency	1.0	2.00061
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89535
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14542
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7796
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19067
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.847
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25288
atractyloside-3695	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.925739
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850061
Swr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999175
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.25557
ARH77	DepMap CRISPR Gene Dependency	1.0	6.1865
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4125
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56297
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4185
HIPK2_overexpression_28_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.47904
SZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856582
TUHR14TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.47565
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11206_KO_Mapk3/Mapk1_SRP331927	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
bupropion-3180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46368
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21312
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02425
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948462
stomach_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.940445
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07084
Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42495
GTEx SmallIntestine 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.67336
EW-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834681
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03464
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.648
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11009
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6824
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946629
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89401
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23412
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.55253
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24332
S-isopropylisothiourea	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47922
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9491
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6956
U4 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11677
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908914
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142994_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76701247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99206
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88609
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr1_42521934_G_A_b38	GTEx eQTL 2025	1.0	1.13935
WM2664	CCLE Cell Line Gene Expression Profiles	1.0	1.90232
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51342
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.2032
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37904
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849326
BRD-K71415389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67738
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13295
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3597
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	0.925493
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10196
BRD-K40210962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33749
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834072
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04031
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45050268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18244
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81379
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31745
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8765
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9976
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842962
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2744
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.9066
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987231
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42155
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.09376
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.876731
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30139
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30655
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	1.68746
BRD-K21470524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05687
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K89257372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29251
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CD81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22677
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09564
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3464
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K93503664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13625
BRD-K25426017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26521
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.85638
BRD-K56520530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42328
BRD-K08899466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97232
BRD-K21036759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16758
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23501
hsa-miR-361-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.959867
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2268
U2904	DepMap CRISPR Gene Dependency	1.0	3.1927
GSE135514_8_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959334
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224215
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5419
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1189
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37556
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	1.54849
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.945555
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15309
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38915
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_13_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25634
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46055
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.941773
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08294
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2281
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BHY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48531
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3321
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.46721
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.83957
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EB-09-JJ93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224555
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49482
SETDB1	ENCODE Transcription Factor Targets	1.0	null
18537972-TableS3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K58025976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44094
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05527
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897396
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73462370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09683
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76797
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32635
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
TT2609-C02	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K84593579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35234
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08709
BRD-K66032509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49841
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26552
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25575
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846886
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17652
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.830504
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6197
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21386
GTEx Thyroid 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.99852
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93239
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60254
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17652
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.50148
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928033
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12916
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873628
hsa-miR-769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Enterovirus 71_8Hour_None_GSE15323	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60468
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04242
CW9019	DepMap CRISPR Gene Dependency	1.0	2.71381
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.03798
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02253
BRD-K85672685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03116
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68722
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8853
GSE129370_2_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98545272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76223
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860688
BRD-A64985224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74083
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39271757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15548
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.4401
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47328
BRD-K98169006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29817
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23892
TRIM28	ENCODE Transcription Factor Targets	1.0	null
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05903
BRD-K99581286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68968
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61925
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.901174
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MF-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25512
BRD-K13086002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01625
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45515
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81475
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.982253
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.25526
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37002
THP-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16978
BRD-K44834268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49647
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02256
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873328
BRD-K20962057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19475
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.099
FOXO1-25302145-T-LYMPHOCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.852035
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89978
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12491
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857929
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PANC1005	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5034
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.82852
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40453
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2986
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intrinsic component of synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.833061
BRD-K55104181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21211
R2TP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7226
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18475
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17483
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.912887
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900653
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990459
IMR32	DepMap CRISPR Gene Dependency	1.0	2.38401
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07639
BRD-K12431811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73415
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99422
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55235
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04192
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7076
EWSR1	ChEA Transcription Factor Targets	1.0	null
Thymic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
BRD-K82432417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3705
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.571
chr1_42442431_A_C_b38	GTEx eQTL 2025	1.0	2.13052
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905678
BRD-K49733809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57349
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832513
BRD-K53224568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45158
BRD-K18149487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64264
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979314
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19342
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-AA_up_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86755
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.155
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EPLC-272H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19543
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21788
BRD-K49103536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00328
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.70407
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.5828
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53243
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58809
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50621
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47435
BRD-K45631723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16615
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979314
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989369
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12256
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30259
chr1_42541282_A_T_b38	GTEx eQTL 2025	1.0	3.51773
BRD-K83684822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07258
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.07373
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95368
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01858
CRCGN015_MCF10A_48H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0653
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79979
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.915888
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.86093
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06893
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52549
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7199
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01611
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26876
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64574
CTDK-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.723
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21353
Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54694941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12083
GSE205163,GSE205164_1_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30409
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06724886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13744
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68927
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.113
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
phenacetin-3992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11321995-41556_2024_1460_MOESM2_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Unique_genes_with_exons_significantly_correlated_with_OTX2_expression_in_Group_3_and_Group_4_MB_tumors_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenosine phosphate-6760	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ESRRG_ESRRG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57741
TE-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.049
H3K9me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8120133-supplementarytables_ddab063.xlsx-Table_S2-Table_S2_Differentially_expressed_genes_in_DUX4-fl_and_DUX4-s_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22915
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19989
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962735
BRD-K39206254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3106
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30522
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25081
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72764
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.51015
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.968529
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04902
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01158
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59549
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62707
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Harderian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
BRD-K91397206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10833
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28411
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57203
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58101
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.24218
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4544
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3556
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5828
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934405
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00294
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28791
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01309
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3638
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12562
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71464
SCC15	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00216
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0597
BRD-K00914921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48834
nfe2l2_00000000_neonate_p3_lung_lof_mouse_gpl1261_gse29632	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.14142
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15719
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55896
LD-39-FL02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240645
Pulse pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.50458
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12886
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57383
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88305
COLO320	DepMap CRISPR Gene Dependency	1.0	2.17148
BRD-K45077605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98386
BRD-K93023309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56197
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.882963
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64593260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71899
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970532
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3271
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSC19	DepMap CRISPR Gene Dependency	1.0	2.85829
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LB771HNC	DepMap CRISPR Gene Dependency	1.0	4.21294
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A41208012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01871
GSE158320,GSE183351_2_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926222
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
BRD-K60799989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32229
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.03312
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942051
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.307
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41365
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956015
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32518
BRD-K69274755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1771
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10225
BRD-K61691014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31646
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42187
Type 1 diabetes mellitus_Thymic epithelial cell_GSE11	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.5104
BRD-K87081268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07742
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0357
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17562
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.854542
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911816
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30386
Perturb_9113_OE_FOXO1A3_SRP188991	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.08684
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16069
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22628
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.831323
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917202
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06822
HCC1395	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K54769228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13385
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PR, GR	MotifMap Predicted Transcription Factor Targets	1.0	null
Hydrogen Peroxide	CTD Gene-Chemical Interactions	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42741
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826462
BRD-K08715918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65522
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3473
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35185
BRD-K82409466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43571
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02774
BRD-A85231803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27568
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02571
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06338
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13154
BRD-K49630774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53051
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05857
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928034
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6456
BRD-K54956860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56026
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.44339
EKVX	CCLE Cell Line Gene CNV Profiles	1.0	2.01851
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3886
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.23767
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:I21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00964
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997287
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10567
BRD-K20331065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31389
glibenclamide-3163	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TC138	DepMap CRISPR Gene Dependency	1.0	5.40612
BRD-K27881453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70379
BRD-K44779670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22987
BRD-K08389897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30304
BRD-K72034681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03102
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2188
127399	DepMap CRISPR Gene Dependency	1.0	3.36475
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02885
KYO1	DepMap CRISPR Gene Dependency	1.0	2.45075
BRD-K28448768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16488
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.25557
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.973467
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.048
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1026
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859522
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963249
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.879191
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2743
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07745
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25802
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61618
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.062
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.58268
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71632
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92662
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37083
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36929
BRD-K09598619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75106
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54107
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17832
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840166
BRD-K04087396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12494
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.147
outer SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25191
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7572
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901969
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912251
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71459
Necrosis	CTD Gene-Disease Associations	1.0	1.17202
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10748141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13851
myclobutanil	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50701
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85814
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82637
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849793
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47794327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00619
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208096
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57381
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37971917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41102
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53846
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.71304
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68069
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938424
hsa-miR-3194-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984592
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.61612
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.878055
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00651
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.21229
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07953
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23846
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.09616
BRD-K38450726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73274
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68779
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13947
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45836
BRD-K59159023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08071
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17541
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07811
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00199
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15501
TAL1-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18665
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891232
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11064
PMC11530610-mmc3.xlsx-WGCNA-CREB3L4_CREB3L4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93223696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42457
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972057
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6617
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.462364
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27634
Systolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
BRD-K87781745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43458
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99731
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31252
hsa-miR-3153	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46631
hsa-miR-4709-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00306
hsa-miR-638	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K81447429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12973
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11919
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973869
fetal	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8146
oxantel-6738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35005
BRD-K44833533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07095
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11919
BRD-K86925685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40949
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834637
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H720	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19372
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967614
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07213
BRD-K90736603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03662
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43669
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.446
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.83667
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32894
ANAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51987
strychnine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11057
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16235
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00781
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932782
tylosin-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29484
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3118	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K01660763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46386
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43307
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17853
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998914
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.33305
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969721
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
diclazuril	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9999
BRD-K49384706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0262
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925159
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231298
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884634
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55429
CRCGN017_MCF10A.WT.HP_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05915
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907218
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05823
GA-77-MH38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215529
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19605494-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEx AdiposeTissue 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	5.6393
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5686
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63712
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68356
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TF1	CCLE Cell Line Gene CNV Profiles	1.0	1.35742
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_3439_KD_Ythdf2_SRP269726	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.53713
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67719
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44512
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46055
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.1243
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18073
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47314501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09672
glis3_19805515_embryonic_pancreas_lof_mouse_gpl1261_gds3812	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.795324
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1584
RAB35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1895
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.873452
BRD-K29684372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66233
BRD-K99413603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23555
Sarcoma_SARC_TCGA-LI-A9QH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4338
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31889353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77267
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC11373733-ABR-13-34_Suppl1.pdf-53-GLI1_GLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924813
CRCGN014_HEPG2_3H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02983
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8806
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926386
prefoldin	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24207
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30025
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1046
BRD-K70751829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41003
PMC10915192-ab-23-0304-Supplementary-Table-S6.pdf-11-SOX6_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22596
TLCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41366
BRD-K50563598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5408
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15477
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8927
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866004
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894167
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919438
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67873
Universal_Human_Reference	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.58928
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03734
GSE186440,GSE186443_3_v_7_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1817
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932664
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91620436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9201
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0264
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.51426
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3772
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6671
Childhood low-grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5088
ARFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38622
RUNX1	ChEA Transcription Factor Targets	1.0	null
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57173
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19989
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30881
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41955
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.354
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13246
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9938
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41099
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25324
BRD-K52339692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51031
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17994
orlistat-6383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53046137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24756
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
YD8	CCLE Cell Line Gene CNV Profiles	1.0	2.36309
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45057266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10107
BRD-K52202153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0325
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04835
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958485
hsa-miR-4291	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18677
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01836
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35275
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49356
PCI30	DepMap CRISPR Gene Dependency	1.0	2.63149
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1619
Lung-lung ciliated cell	Tabula Sapiens Gene-Cell Associations	1.0	7.07949
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.25421
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05827
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65697
sulfamethoxypyridazine-3711	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887949
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4022
VDR-24787735-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90273
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51697
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14391
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
cloned	GeneRIF Biological Term Annotations	1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19473
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02288
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26707
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02359
BRD-K44861255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31128
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35435
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21363
TMEM185A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35038
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02839
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17652
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95666495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7313
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03876
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937162
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901403
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17652
BRD-K05286676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40588
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24475
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862691
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68044
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05809
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8758
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67399
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45118
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6523
tilmicosin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46308
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6006
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22534
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66842
BRD-K48140215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13851
LS1034	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46606
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49292
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19387722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8907
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992487
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940492
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01767
BRD-K01960204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60993
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10596
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835204
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7938
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3245
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0013
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9538
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1659
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99108
U87MG	CCLE Cell Line Gene Expression Profiles	1.0	1.5178
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43445
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73085
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40322
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18937
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59753
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30694
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989171
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
D283MED	CCLE Cell Line Gene Expression Profiles	1.0	2.53225
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35333
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47437
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_0_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K75807957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25115
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16307
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.07979
clemizole-2301	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05998
Perturb_16108_KO_Dnm2_SRP139918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.20076
NCI-H2444	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29687
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0509
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75614
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845436
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76608
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48538
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6342
BFTC-905	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938861
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33067
organelle	GO Cellular Component Annotations 2015	1.0	null
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28109
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14944
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.061037
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26853
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242163
Lung adenocarcinoma_LUAD_TCGA-97-7546-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15895
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.11445
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.22833
BRD-K24156533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.94907
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979314
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.858746
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.14637
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958069
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48906
JK1	CCLE Cell Line Gene Expression Profiles	1.0	1.97139
SF295	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54456
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4138
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05974
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.979593
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25378
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K17136501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05927
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227073
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45753
EZH2	ENCODE Transcription Factor Targets	1.0	null
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.028
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02899
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	1.41258
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-134	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39114
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
hsa-miR-539	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.89699
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16829
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
U5 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.627
NCIH1781	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9004
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1566
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25363
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66299
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46559
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22664
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59225
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.193
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06848
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20009653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76053
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83805
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31305
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36278687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6436
HEL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.661
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06543
NCIH1793	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48234
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61374
BRD-K13526564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26363
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15888
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03152
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65626
BRD-K81124412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25325
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895475
LN319	DepMap CRISPR Gene Dependency	1.0	2.64201
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81886
BRD-K36111748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06542
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	2.68276
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96006
Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07002
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979314
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17994
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23633
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32979
BRD-K12741517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05309
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2038
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7604
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0338
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14138
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.998296
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6008
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.935616
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01324
Inflammation	CTD Gene-Disease Associations	1.0	1.22566
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96522
VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE	ChEA Transcription Factor Targets 2022	1.0	null
vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K44260904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13089
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07742
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40683
GSE155567_1_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46623934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06246
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01671
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00808919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47619
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01132
hsa-miR-375	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32053
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KMRC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78232
BRD-K37912617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00268
BRD-K14359826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16019
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.667
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8041
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1939
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1454
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62229896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40785
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118077_1_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0822
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40061
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02862
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1208
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45399
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53697
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02075
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04059
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1713
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989983
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5312
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F2-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04284
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66037
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0786
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61924932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.69798
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25351
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944443
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49402
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.593912
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64823749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23099
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2464
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1182
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63013
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996932
BRD-K29441085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65709
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.51364
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34896
BRD-K48691065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75861
LOU-NH91	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89962
MYOG	ENCODE Transcription Factor Targets	1.0	null
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00275
HT1376	DepMap CRISPR Gene Dependency	1.0	3.18237
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27529
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828067
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35477
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45256
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897162
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
decreased prepulse inhibition	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01791
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05145
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1077
Fibrosis	CTD Gene-Disease Associations	1.0	1.13007
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06208179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25969
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88009
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58205
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49146
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26656
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.051
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912661
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49294047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91762
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01555
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36015
BRD-K70054078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03628
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0296
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Clitoral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.34
RXRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1385
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01647
Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3073
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5891
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16044
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21603
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO684	DepMap CRISPR Gene Dependency	1.0	5.89221
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.81783
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3414
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01429
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3433
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0812
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28486
BRD-K66717300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14627
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58553
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28639
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868014
androsterone-5696	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35442
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17652
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64626569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21602
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73794
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4665
BRD-K31805261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06225
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893537
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2Z	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8093
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69659917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21273
SPI1	ChEA Transcription Factor Targets	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.903544
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.57822
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135514_2_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU16	DepMap CRISPR Gene Dependency	1.0	3.60353
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9515
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64942
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36877
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3515
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905174
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6788
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0554
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990623
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68499
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20233
Fibrillar collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.076
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31623
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93966
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32533
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27026
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1	ChEA Transcription Factor Targets	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84569
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2143
BRD-K26634905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78096
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71804
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.42104
GTEx AdiposeTissue 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	13.9523
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1646
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916089
BRD-K51175229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69209
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0062
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891506
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22122
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23371
BRD-K94139496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13818
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68798
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.957765
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13209
BRD-K27616520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09543
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18928
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BB49-HNC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826956
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926284
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
BRD-K47620421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53565
k562	HPA Cell Line Gene Expression Profiles	-1.0	-0.833397
BRD-K63212062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20913
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07284
BRD-K28640166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38182
SKHEP1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85038
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17773
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01866
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07784
CEBPB	ENCODE Transcription Factor Targets	1.0	null
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45249
BRD-K05841284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45946
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51332
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889471
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	2.48651
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47482563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52126
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1768
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80736363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18549
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2437
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06583
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01748
SKN3	DepMap CRISPR Gene Dependency	1.0	2.45633
BRD-K22390389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37112
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.992606
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69696
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5998130-41467_2018_4619_MOESM7_ESM.xlsx-specificity_NCOA3-Gene_Name_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52912
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RNPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0152
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42266
BRD-K24499562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01786
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39496
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90914
BRD-K61924304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36343
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825424
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83287
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4479
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_UP_AA_UP-AA_UP_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
brain	GeneRIF Biological Term Annotations	1.0	null
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tracazolate-6619	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.25
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2611
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91266
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6233
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89926
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K24512597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72734
hsa-miR-580	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2806
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06219
BRD-K48389518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18032
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8118
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948085
Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02628
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02232
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867729
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05354
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.0148
BRD-K64751430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01569
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83581
BRD-K05463922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20297
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4976
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04785
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08274
PMC10944835-41467_2024_46639_MOESM4_ESM.xlsx-SD17-Supplementary_Data_17_Differentially_expressed_genes_according_to_homozygous_genotype_at_the_TWIST1_locus_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.74788
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50652
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03606
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6215
NCI-H748	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96138
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14714
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38657
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36756
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.51727
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.68144
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81175414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.29754
BRD-K31666794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05601
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45814
BRD-K46562329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02539
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39476
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06825
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35705
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1313
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	4.76717
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43442
SMC3	ENCODE Transcription Factor Targets	1.0	null
cSARS Bat SRBD_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.88085
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLE	DepMap CRISPR Gene Dependency	1.0	6.8476
BRD-K62497619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51106
BRD-K28039328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54517
PMC4053969-gb-2013-14-7-r81-S3.XLSX-YB1-targeted-genes-gene_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77894
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14577
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
BRD-A98795688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44286
GAMG	CCLE Cell Line Gene Expression Profiles	1.0	1.34938
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01813
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUW-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62325456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01265
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81927
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19894
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25078
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07766
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr1_42520767_G_A_b38	GTEx eQTL 2025	1.0	1.82257
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2031
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05068
BRD-K42964952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7144
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25642
BRD-K74665927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33086
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.3755
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26443
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.6447
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932366
BRD-K79887921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22296
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19989
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	2.18197
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-3679-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.71673
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18073
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4102-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.874554
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39229
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96557
BRD-K67096761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04568
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EWSR1_KD_GDS4962_467_human_not specified	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI 460	BioGPS Cell Line Gene Expression Profiles	1.0	1.05856
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16451
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5886
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856191
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49304
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0246
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56066
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K23430405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11919
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37722
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87785
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	2.16115
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3795
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883243
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899003
BRD-K48332223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08381
BRD-K37262603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.07897
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19326
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85071
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64856
U937	CCLE Cell Line Gene Expression Profiles	1.0	1.37668
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05728
BRD-A98888138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46536
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46112
BRD-K42995703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37354
HCFC1	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18198
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79249
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36929
GSE95685_2_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10525
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.75881
PMC7595190-41598_2020_75453_MOESM6_ESM.xlsx-MLL_EFS_groups_DEGs-Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901528
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMRC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4455
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Banded collagen fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875364
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955009
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93751
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20827
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35731
BRD-K44402256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0428
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22211
BRD-K66907139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42113
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913899
BRD-K30964167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78169
cdkn1b_18180298_3t3_lof_mouse_gpl1261_gse9161	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.356426
BRD-K10696228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82181
BRD-K93567937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03198
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21867
BRD-K84199148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41348
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0336
MFE296	DepMap CRISPR Gene Dependency	1.0	5.69366
Spitzoid melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372177
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKNMC	DepMap CRISPR Gene Dependency	1.0	2.00698
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28159
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.946975
BRD-K74568359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74933
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.947663
SW837	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36395
BFTC905	CCLE Cell Line Gene CNV Profiles	1.0	2.59933
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945362
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77859
posteroventral (inferior) parietal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853264
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-943	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4663
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64317740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25623
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
LUDLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41484
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.77285
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.96685
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.96976
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6439
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Systolic Pressure	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
BRD-K67194214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98099
lactobionic acid-6605	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06472
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1722
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.147
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.53092
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0311
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9936
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-3.6179
BRD-K14250524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13732
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03706
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67937
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	2.29519
KYAE1	DepMap CRISPR Gene Dependency	1.0	5.04269
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22589
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32998
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925258
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42558
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71698
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69812
CAS1	DepMap CRISPR Gene Dependency	1.0	3.23537
CRCGN014_HEPG2_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00234
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895854
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.24803
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828632
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849872
BRD-K79152256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02911
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984735
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0276
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901362
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2972
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23731
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3865
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31166
TOX_01_332	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60764
BRD-K01699883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70105
BRD-K00083518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31699
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902102
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34903
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE185519_1_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11697
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.31968
LB373-MEL-D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.58269
BRD-K62372121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32855
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860863
BRD-K63102090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72619
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12782
aminohippuric acid-5394	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ML-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
RMG-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852958
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16325
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.971246
LXF289	CCLE Cell Line Gene CNV Profiles	1.0	1.61596
levisoprenaline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19447
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02213
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93406
CAOV4	CCLE Cell Line Gene Expression Profiles	1.0	1.37468
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941918
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3135
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8021
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K42679315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1977
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1538
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12986
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96005
chloramphenicol-1837	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_7308_KD_IER3AS1_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.15526
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92662
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10682
BRD-K57343972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08947
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74112
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2456
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17257
BRD-K94088690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59767
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26118
BRD-K50149147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11015
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35593
WDR5-24793694-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K22137463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88392
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.78982
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.43613
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860836
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27028
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14791
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53144
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19191
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24907
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50364
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968785
UACC893	DepMap CRISPR Gene Dependency	1.0	2.62112
BRD-K56437119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33065
EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IF-A3RQ-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNRPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28187
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Theophylline	CTD Gene-Chemical Interactions	1.0	null
doxycycline_mus musculus_gpl2872_gse33875	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1833
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03113
8MGBA	CCLE Cell Line Gene Expression Profiles	1.0	1.41893
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61354
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21053
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Thymic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.12676
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13549
PMC8494348-pone.0257161.s002.xlsx-only_OXT_NOT_ext-OXT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx AdiposeTissue 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	6.39691
LK2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54905
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826316
BRD-K23503923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10255
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39117
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.921903
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.13259
BRD-K66013406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26441
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K84936524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23915
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.01732
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38742
BRD-K87853964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76321
hmc1	HPA Cell Line Gene Expression Profiles	1.0	2.7193
chr1_42450873_A_G_b38	GTEx eQTL 2025	1.0	1.16973
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22059
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34723
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01828
ZNF722	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11453
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5664
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1119
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862264
BRD-K30548577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31891
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6939
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.267
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853714
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.846573
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.2706
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58028568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79326
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53362
BRD-K09863466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58798
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33405
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1277
BRD-K51937785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31456
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6943
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836434
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06973
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08042
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36574
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.33914
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.841847
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11598
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48514
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06979
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21254
DOK	DepMap CRISPR Gene Dependency	1.0	5.28985
BRD-K34451734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37556
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52906
BRD-K56563758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66032
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70349
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57381
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18561719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25004
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35064
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6467-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6757
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41315
GTEx Thyroid 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	4.22105
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874177
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	1.61216
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979314
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20047
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55456
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
tomelukast-222	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93574
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CTCFL_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04238
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889203
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65433
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.64343
MEWO	CCLE Cell Line Gene Expression Profiles	1.0	1.75456
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76638
BRD-K71139459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5986
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44966
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.842401
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.46374
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4619
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01243
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920976
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903957
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.147
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64801
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NP5	DepMap CRISPR Gene Dependency	1.0	2.73225
BRD-K23835343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30104
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.182
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33125
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K41289356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66394
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2384
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51494
hsa-miR-300	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
BRD-K54506283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32778
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08569
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DIFI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K87230984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09694
GSE77178_2_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09492
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32131
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0577
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
YD8	DepMap CRISPR Gene Dependency	1.0	8.87696
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
BRD-K53458780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26871
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37879
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937657
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59387
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61694
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89724
BRD-K48338059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39864
NCIH520	CCLE Cell Line Gene CNV Profiles	1.0	1.79132
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60965
astrocytes	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.37386
BRD-A54389315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16873
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11919
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11919
CNST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13837
chr1_42480019_G_A_b38	GTEx eQTL 2025	1.0	1.62208
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33564
BRD-K71253424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08799
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58243
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74817844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33553
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01671
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2085
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2029	CCLE Cell Line Gene CNV Profiles	1.0	1.9279
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12694
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25084
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77504
NCOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11222
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81035
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49954
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3803
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69092
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10831
BRD-K57027644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45464
BRD-K83307202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11758
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79336
stat3_18070348_alveolar_type_2_epithelial_lof_mouse_gpl1261_gds3106	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.86122
Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833464
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24036
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41912
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43585
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915915
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7398
TYKNU	CCLE Cell Line Gene CNV Profiles	1.0	1.34351
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84643
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2414
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17723
BRD-K84439371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18465
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47382
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872301
BRD-K56351525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23098
GSE153124_4_v_3_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	4.01794
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_10_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74251295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24498
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1614
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08387
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981895
BRD-K75588273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08779
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.977883
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9768
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07208
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47758
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8002-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.4521
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829291
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10801
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MHHNB11	DepMap CRISPR Gene Dependency	1.0	3.40174
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28207
BRD-K34009110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45118
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88974
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07425
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70895
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.96685
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937504
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2221
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4527
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPACA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66914
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19114
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9885_KD_HNRNPL_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.57661
GSE127916_1_v_4_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4, COUP	MotifMap Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KK-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39011
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26638
BRD-K99847716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04337
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23101
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854501
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68683482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38809
MKN45	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74259
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01979
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K89638177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90765
RFX1	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843978
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.155
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18827
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51568355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0711
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03181
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	1.08772
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18275
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12261
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32318
CREM	ChEA Transcription Factor Targets	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07322
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49199
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.905913
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881037
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.864203
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935787
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19232
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81145
BRD-K93186184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53072
CRCGN016_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17685
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24498
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02274
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10704
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.946077
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26196
BRD-K88539660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26083
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07895
GSE160373_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67493
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00988
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33463
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6782
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9855
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.11445
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857568
PMC9038526-mmc1.xlsx-postCOVID_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26235
BRD-K85395981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32644
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07761
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3588
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847735
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08042
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22563
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87399
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33723
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85864
BRD-K65506286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58998
U-266 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	3.00943
BRD-K71501826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6377
BRD-K93516545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95132
Perturb_4385_KD_PC4_SRP340634	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K20203758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17302
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23626
BRD-K46098747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24144
SPI1	ENCODE Transcription Factor Targets	1.0	null
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863611
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3941
BRD-K54484733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19373
MTFR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90669
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07732
OE33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4702
Perturb_11297_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.3589
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.10598
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AGPAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24486
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.64706
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28796
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82954
BRD-K57782577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01737
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984178
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07356
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15127
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899003
MAZ	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870682
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.918948
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18752
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830331
BRD-K35848924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45362
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71131
VDR-24763502-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K96280720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33279
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43931
Brain Lower Grade Glioma_LGG_TCGA-CS-4941-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40706
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32998
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NM-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.79662
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01266
HEL-92.1.7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A101D	CCLE Cell Line Gene Expression Profiles	1.0	1.85265
BRD-K14041149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20296
BRD-K42214389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31675
BRD-K67520049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59791
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947828
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46149
Hypertrophy	CTD Gene-Disease Associations	1.0	1.04389
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.956269
FLI1	ChEA Transcription Factor Targets	1.0	null
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0759
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37018
BRD-K59587063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07623
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35599
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DU4475	DepMap CRISPR Gene Dependency	1.0	2.79062
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24949
GSE182680,GSE182683_10_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4164-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.931002
BECKER	DepMap CRISPR Gene Dependency	1.0	3.4401
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936472
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41725
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
B-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42165
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893669
BRD-K49552510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66937
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27405
EZH2	ChEA Transcription Factor Targets	1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31215362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0202
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1447
BRD-K96817767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36876
NCIH1648	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20636
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1302
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.5703
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51352
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37824
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.76386
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32703
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17143
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17771527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32424
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09568
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08128
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52551
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26535
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918821
GSE212760_0_v_1_fxr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI H23	BioGPS Cell Line Gene Expression Profiles	1.0	0.885239
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.07182
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.11445
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16806
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6279
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876355
BRD-K24479270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39483
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40G-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87053028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4209
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05298
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848419
PMC10915192-ab-23-0304-Supplementary-Table-S5.pdf-41-FEV_FEV	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867701
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88574
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K09071517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24141
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866641
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39348
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34431
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51535
hsa-miR-409-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
risedronate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2632
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2618
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828723
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.55071
BRD-K45153693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46265
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
MOLP2	CCLE Cell Line Gene Expression Profiles	1.0	3.40822
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51641263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03117
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3448
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
Pilocytic astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57402
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00299
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K51898276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04268
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02395
Psammomatous meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4355
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85696
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7804
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30952
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66456
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59625
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.85409
BECKER	CCLE Cell Line Gene CNV Profiles	1.0	1.64198
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.917974
BRD-K01827055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08275
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18797
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83378
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958115
Acute Myeloid Leukemia_LAML_TCGA-AB-2826-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased prepulse inhibition	MGI Mouse Phenotype Associations 2023	1.0	null
JURLMK1	DepMap CRISPR Gene Dependency	1.0	2.40895
BRD-K24514314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20637
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.193
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66266
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06018
tonsil	HPA Tissue Gene Expression Profiles	-1.0	-0.920994
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86875
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09441
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93693
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68873
BRD-K54839019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83776
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896548
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16938
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.923
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980165
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80218
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41999
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31238
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07153
NCIH226	DepMap CRISPR Gene Dependency	1.0	5.78067
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89254
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88493
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39348
BRD-K62803063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11847
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2392
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49352
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873547
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34851865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06971
BRD-K11630986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03291
PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41406
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.933821
BRD-K00300115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15526
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53656
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.05498
BRD-K82578220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.65304
characterized	GeneRIF Biological Term Annotations	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.901839
GSE199034_1_v_0_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K59049340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07204
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
BRD-K07979116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06007
18537972-TableS2	GeneSigDB Published Gene Signatures	1.0	null
NCIN87	DepMap CRISPR Gene Dependency	1.0	6.99424
BRD-K17070436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06167
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.38017
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13701
Lung adenocarcinoma_LUAD_TCGA-78-7143-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93675803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38715
CORL24	CCLE Cell Line Gene CNV Profiles	1.0	2.10193
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23197
AICD_Induced  expression / Over-expression_GDS1979_288_human_SHEP-SF neuroblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73858940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2866
NFKBIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26275
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975467
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03327
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2258
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05006
BRD-K35726223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25728
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37302
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6052
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836271
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24861
chr1_42572013_C_T_b38	GTEx eQTL 2025	1.0	2.75416
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7092
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7486
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5926
heparin_homo sapiens_gpl570_gse12710	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	1.45273
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00467
496100375_FWM_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07386
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_12_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx Thyroid 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	7.51226
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13864
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48264
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K24496049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08119
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63102
BRD-K53191200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12246
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.923
BRD-K54660148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02844
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01555
BRD-K44787496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5332
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47719
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871613
hsa-miR-381	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1291
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
albendazole-3164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.21759
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957187
PMC7893038-41598_2021_83450_MOESM3_ESM.xlsx-DBP_Baseline_AMR-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11731
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08889
Setleis syndrome_Skin fibroblast_GSE16524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.736872
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38994
PRPF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18275
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6994
BRD-K55238630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.17263
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951594
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942779
EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0283
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42911
GSE182680,GSE182683_10_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8305
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20628
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11898
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30575
BRD-K36197756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26194
DDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77711
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26684
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17294
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.20026
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909711
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.886896
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNGM	CCLE Cell Line Gene Expression Profiles	1.0	1.74407
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0639
BRD-K14732815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87574
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32656
BRD-K24047785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24789
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9486
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.11445
Perturb_6588_KO_Cabin1_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.7526
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0311
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6487
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
terguride-5694	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0344
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86245
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53711
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A8BU-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06673
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.858746
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840605
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29889
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35358
SW954	DepMap CRISPR Gene Dependency	1.0	2.76447
BRD-K15474464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03105
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918104
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4447
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5196-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.965102
BRD-K67460571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16522
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902291
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78269577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00979
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.991956
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967614
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26816
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.954392
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75273
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67965
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.76296
hsa-miR-1976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-3135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891084
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969688
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.23316
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28362
BRD-K79020643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32523
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85462
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976373
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49352
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93307
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01024
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4623
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
SKMEL2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.183
NCIH727	DepMap CRISPR Gene Dependency	1.0	2.13788
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	3.63717
MXI1	ENCODE Transcription Factor Targets	1.0	null
PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_I-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17954
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5022
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.91402
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.75704
BRD-K03093950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80267
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06872
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00851
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3824
FOXA1	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28342
TMK1	DepMap CRISPR Gene Dependency	1.0	4.09293
GSE155567_2_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	1.0	null
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56003
PMC5323140-oncotarget-07-65090-s002.xlsx-DUX4_ONLY-Gene_symbol_db2db_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41A-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990895
Pancreatic acinar cell adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.97766
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38481
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18281
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.18622
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0641
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21472
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.63455
BRD-K77108448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75977
BRD-K46942548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19439
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94540403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51845
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932755
BRD-K20028734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40789
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5472
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851872
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.854753
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14504
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.62322
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	0.90298
BRD-K13844473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15005
PMC8104016-hcg-12-e002353-s010.xlsx-mTHP1-LPS_30kb-Interacting_Gene_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.948568
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29493
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1373
HS229T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62866
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18309
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10095
BRD-K97391170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31332
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2902
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.947715
BRD-K39348592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98672
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49267
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14595
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JHH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MOGGUVW	DepMap CRISPR Gene Dependency	1.0	4.00867
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2827
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9754
BRD-K04116560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1387
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.945615
Apical cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
BRD-K19159562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78425
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24705
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.18355
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.59511
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49132774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01293
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04258
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27599
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1665
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.981124
CAKI1	BioGPS Cell Line Gene Expression Profiles	1.0	0.983604
BRD-K20585111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09189
NDUFA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21482
SCC9	DepMap CRISPR Gene Dependency	1.0	2.67986
BRD-K37308886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25304
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50862
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32998
labetalol-3167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16505
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16777
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50853
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31316
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39091
hsa-miR-4501	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K10505056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03661
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14839
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.26469
BRD-K10055064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25265
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07805
ZIC5_01_285	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.60214
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06436
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53014
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21108
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.965917
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17522
BRD-K41762421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17363
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.946737
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03185
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.856525
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31922
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70621
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.929451
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918104
SW403	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20441
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0559
pdx1_22135308_duodenum_lof_mouse_gpl1261_gds4348	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.037808
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0264
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EXOC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39507
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:D23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01862
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1792
chr1_42521099_A_G_b38	GTEx eQTL 2025	1.0	1.49142
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78275
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87037
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09919
BRD-K50146767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30225
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3016
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919056
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73765
rpmi8226	HPA Cell Line Gene Expression Profiles	-1.0	-1.45271
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2506
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.70155
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78145
RAB3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74225
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30383
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.33827
BRD-K38519585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63352
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983092
BRD-K28885073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10686
Laryngeal cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.475
BRD-K65913831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15272
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45851
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0868
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11549
RPS3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46345
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76788397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2788
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25207
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6771
BRD-K94385157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1404
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77143
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10871
MCF7_Givinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00759592
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83547
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LS123	DepMap CRISPR Gene Dependency	1.0	2.89198
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63699
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77847
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26453
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.82917
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.856196
PCI6A	DepMap CRISPR Gene Dependency	1.0	2.98344
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JVM2	CCLE Cell Line Gene Expression Profiles	1.0	1.50681
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2462
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68494
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01173
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78584
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73804
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85232
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.52094
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14889
BRD-K29258781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31496
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34169
BRD-K84278600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01024
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956717
molt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.13315
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1601
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.9811
BRD-K49662642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28644
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12582
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28502
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895182
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911109
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834637
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33165
19621087-Table1e	GeneSigDB Published Gene Signatures	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18912
BRD-K75281646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15256
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.8126
FHIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86227
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0575
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K45339826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15353
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959702
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1604
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919044
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16522
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K60295429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12763
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23453
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65148
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907227
TP53-32428506-HUMAN-LIVER-HEPTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K05704547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00397
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46559
Age At Menopause	DisGeNET Gene-Phenotype Associations	1.0	null
HCC70	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00909
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52257
Preputial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
IALM	CCLE Cell Line Gene CNV Profiles	1.0	1.41636
BRD-A70099008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46667
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02116
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	2.2525
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850057
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-12-HIVEP3_HIVEP3	Rummagene Transcription Factor Associations 2026	1.0	null
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07443
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23101
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.995981
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-450b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.923
BRD-K90316899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28162
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.19732
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96198
ECGI10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38367
BRD-K05710256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17999
LNCAP	BioGPS Cell Line Gene Expression Profiles	1.0	1.15333
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11408
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54857
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72917
BRD-K99331869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30586
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62196
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836486
BACH1_02_188	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62081
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43452
Salivarygland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05666
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.91449
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21434
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25672
FGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35666
MFE280	DepMap CRISPR Gene Dependency	1.0	2.76888
ALAS2_OE_GDS2118_74_human_Blood	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30703
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13985
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.24529
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93617
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45393
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58979
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_UP_NR2F1_ind_UP-NR2F1_Ind_UP_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
suprofen-4005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K50216176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3129
BRD-K46936325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5885
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956814
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8129
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.85045
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04166
Respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.004
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95418
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39738
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6769
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.317
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4432	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
THP1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82065
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256337
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2747
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02842
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6706
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.59308
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34281
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Upregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_10_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K31575862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06137
BRD-K30699866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11833
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68079
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55072
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.88855
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999825
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15935
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K79179851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10623
GSE135514_8_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51862
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45567
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1185	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
inner SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05693
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918104
BRD-K11612998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08972
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19568
BRD-K10812033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15076
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40399
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.23095
ELP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94914
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94993
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98222
DCAF12L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03697
SKPNDW	DepMap CRISPR Gene Dependency	1.0	2.1943
BRD-K06863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0567
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.37476
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.88891
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873213
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	1.68123
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137137_1_v_0_rcor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12336887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20277
SCH	DepMap CRISPR Gene Dependency	1.0	5.5438
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59527
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958503
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893683
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82834
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC10568675-JCMM-27-3157-s003.docx-70-RFX3_RFX3	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
Elk-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929751
BRD-K24377650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68644
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69296
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01546
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17018
MAFK	ENCODE Transcription Factor Targets	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7028
MAP3K20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01786
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96223
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.13768
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931252
RPAP3/R2TP/prefoldin-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.227
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18414
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38829
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03707
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36575
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18662
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.919404
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMK115	DepMap CRISPR Gene Dependency	1.0	4.50353
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8584
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A897-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56013842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04298
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98108
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924079
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13267
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2409
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894405
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885076
UMUC7	DepMap CRISPR Gene Dependency	1.0	6.65219
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70383
Perturb_15357_KO_Tfap4_SRP212619	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.46259