association dataset threshold value standardized value T24 CCLE Cell Line Gene Expression Profiles -1.0 -1.75924 H3K4me1_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.07187 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923366 subcallosal cingulate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.52576 Perturb_10048_KD_NONO_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.81575 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.42501 Perturb_10027_KD_APOBEC3C_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.33856 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_10114_KD_NCBP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.96477 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_10153_KO_ARID4B_SRP255645 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.72021 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13701 Perturb_14760_KD_LATS1/LATS2_SRP345234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.75835 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.42494 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 4.04113 Perturb_9649_KD_T208_SRP327946 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.80796 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.78423 Perturb_8331_KD_METTl14_SRP167173 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.43962 Perturb_3915_KD_CTNNB1_DRP003300 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.28253 Perturb_9927_KD_SRSF5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.43339 KMRC2 DepMap CRISPR Gene Dependency 1.0 2.68428 VZ in rostral cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11488 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93941 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.65517 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.75057 SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.12695 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49963 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5044_KO_Ssu72_SRP167695 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.25712 CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2136_KD_ARVCF_SRP186778 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.33623 DU4475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.09262 H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_341_KD_EGFP_SRP076553 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G5-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_7950_KO_BAZ1A_SRP100570 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.90158 PGR-26153859-MCF-7-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.9839 H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_2421_KD_DDX54_ERP105312 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.4318 8305C CCLE Cell Line Gene Expression Profiles -1.0 -3.02162 Perturb_7751_KD_RPP20_SRP155278 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.5736 G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07339 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TYKNU DepMap CRISPR Gene Dependency 1.0 2.69941 Perturb_694_KD_SREBP2_SRP064735 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.8799 Perturb_8083_KD_FASTKD2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.27182 heart muscle HPA Tissue Gene Expression Profiles -1.0 -1.01772 TEAD4_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.954607 CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37159 Perturb_10200_KD_HNRNPUL1_ERP118119 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_547_KO_SA1_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.47004 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.885253 Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GRANTA-519 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.60456 SKNMC DepMap CRISPR Gene Dependency 1.0 4.3249 Perturb_7537_KD_RREB1_SRP265233 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.31951 SKMEL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.87555 Perturb_15701_KO_BNC2_SRP327109 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.11584 COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985478 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.01419 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.51264 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.52806 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985478 Perturb_9924_KD_RBM22_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.15666 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SOX17 JASPAR Predicted Transcription Factor Targets 1.0 null GSS CCLE Cell Line Gene CNV Profiles 1.0 1.44365 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_693_KD_SREBP1_SRP064735 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.06031 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GMS10 CCLE Cell Line Gene CNV Profiles 1.0 3.26266 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_8274_KD_SERBP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.33537 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.987808 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.09138 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.889417 iPS-20b Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.05678 Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pc3 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.01493 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null NB-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COLO 800 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.845509 JHOS4 CCLE Cell Line Gene Expression Profiles -1.0 -1.46496 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1422 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1386 HCC1482 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.83067 H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Perturb_344_OE|KD_SMAD1|GDF6_SRP076553 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_9101_KD_MSX2_SRP304247 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.23265 H3K4me1_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3748_KD_NORAD_SRP149071 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.49774 Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JVM3 DepMap CRISPR Gene Dependency 1.0 2.11376 Perturb_9916_KD_IGF2BP3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.92941 fallopian tube GTEx Tissue Gene Expression Profiles 1.0 1.70448 NCIH211 CCLE Cell Line Gene CNV Profiles 1.0 1.73653 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.922664 Perturb_14745_OE_MEOX2_SRP330486 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.04819 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2762_KD_BRG1_SRP077334 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.38853 Perturb_3640_KO_BRD4_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.00152 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4P0-01A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9401_KD_MYCN_SRP104120 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.27576 SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.7572 Perturb_15557_KO_SLFN11_SRP327912 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.62414 Kidney Chromophobe_KICH_TCGA-KN-8431-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03397 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07681 Perturb_15404_KD_NRP2_SRP377764 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_11525_KD_SNW1_SRP092641 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.07437 RMGI DepMap CRISPR Gene Dependency 1.0 4.894 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12912 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.977313 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.93103 H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9991_KD_ILF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.49644 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.879053 USF2 ENCODE Transcription Factor Targets 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.09968 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.901422 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.04988 RT4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06574 NO11 DepMap CRISPR Gene Dependency 1.0 2.28034 Perturb_7431_KO|KD_RBFOX2|RBFOX1_SRP068106 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.63987 SIN3A ENCODE Transcription Factor Targets 1.0 null Perturb_9817_KD_E2A_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.4295 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43798 EP300 ENCODE Transcription Factor Targets 1.0 null HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06865 SH10TC CCLE Cell Line Gene Expression Profiles -1.0 -1.51543 Perturb_8089_KD_HNRNPA2B1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.57698 USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lateral parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02086 CA46 CCLE Cell Line Gene Expression Profiles 1.0 2.17822 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA1_OE_GDS4957_144_human_LNCaP prostate cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null A-Netherlands-602-2009(H1N1)_36Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -3.48187 Perturb_10438_Mut_Adad2_SRP262140 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.14863 SMC3 ENCODE Transcription Factor Targets 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS20 CCLE Cell Line Gene CNV Profiles 1.0 1.47529 Perturb_7327_KO_KMT2C_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.31787 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20665 dorsolateral prefrontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.980488 CHD2 ENCODE Transcription Factor Targets 1.0 null U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914526 Perturb_13495_KD_IGF2BP1_SRP291710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.66081 KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.50689 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.57197 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null heart GTEx Tissue Gene Expression Profiles -1.0 -0.862225 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21297 TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC6 ENCODE Transcription Factor Targets 1.0 null NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.44842 POLR2AphosphoS5_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7160_KD_ACTG1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.57568 Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34183 SLR24 CCLE Cell Line Gene Expression Profiles 1.0 1.36845 POLR2A ENCODE Transcription Factor Targets 1.0 null CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.911456 Perturb_13681_KD_ATG5_ERP127841 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 DAUDI CCLE Cell Line Gene Expression Profiles 1.0 1.50977 Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW626 DepMap CRISPR Gene Dependency 1.0 3.32506 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.42634 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.908445 Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.59865 Perturb_3892_KO_Lonp1_SRP301760 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.03562 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11971_KO_SUZ12_SRP327198 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.55689 Perturb_6838_KO_DOHH_SRP199981 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.772 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.56699 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7444_KD_LOC550643_SRP096253 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.32318 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20992 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00326 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.997519 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17320_KO_miR106b~25_ERP121195 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.0718 ZNF143 ENCODE Transcription Factor Targets 1.0 null TRIM28 ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1500 CCLE Cell Line Gene Expression Profiles -1.0 -1.51779 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06865 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03676 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -3.06501 Perturb_8787_KO_HNF6_SRP217514 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.07911 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.97155 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.905252 MOLT16 CCLE Cell Line Gene Expression Profiles -1.0 -1.95846 Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2877-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14841_KD_GCM1_SRP358680 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.1261 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_2715_KO_TET1_SRP110516 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.3939 Perturb_2076_OE_PUM1_SRP072710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.32784 SAOS2 DepMap CRISPR Gene Dependency 1.0 3.47361 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null ACHN CCLE Cell Line Gene CNV Profiles 1.0 1.81991 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.880072 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.57332 I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.974981 MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.52867 striatum_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00332 H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17948 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.978948 Domain of unknown function DUF4200 InterPro Predicted Protein Domain Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7347_KD_ALKBH5_SRP070463 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.90407 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6234 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_532_KD_TCF4_SRP234742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.07453 primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.85392 Perturb_15442_KD_MED25_SRP212208 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.49643 Perturb_7164_KD_FTH1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.11796 SUDHL8 CCLE Cell Line Gene Expression Profiles 1.0 1.44868 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.917133 Perturb_6141_OE_PPP1CA/PPP1R8_SRP118980 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.07308 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EGR1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HT-144 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.969219 CHLA90 DepMap CRISPR Gene Dependency 1.0 5.34968 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_362_KD_RAC1_SRP387923 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.02674 Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14317_KD_PVT1_SRP341441 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.0929 Perturb_163_KD_RAC1_SRP387923 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.86042 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.57197 Perturb_11951_OE_MYC_SRP355809 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.962527 Perturb_6756_KO|KD_UPF3A/UPF3B|UPF1_SRP327782 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.2878 Perturb_10025_KD_TIAL1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.91289 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2683_KD_SNHG7_SRP179498 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.8115 Perturb_8050_KD_METTl14_SRP167173 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.18061 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.80558 ventral posterior inferior nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06459 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GI1 CCLE Cell Line Gene CNV Profiles -1.0 -1.33817 HUPT4 CCLE Cell Line Gene CNV Profiles 1.0 1.86771 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.20011 Perturb_8244_KD_TAF15_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.4921 Perturb_12958_KO_KDSR_SRP308393 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.18897 cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.961466 Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35096 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.71102 Perturb_5548_KD_ASC_SRP310464 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.87678 BPH1 DepMap CRISPR Gene Dependency 1.0 6.21303 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UACC257 CCLE Cell Line Gene CNV Profiles 1.0 2.13154 Perturb_4592_KD_EBNA1_SRP064652 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.33217 CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45187 Perturb_9966_KD_SF3A3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.3425 blood vessel GTEx Tissue Gene Expression Profiles -1.0 -0.92986 SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superior temporal gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.831316 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914526 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06634 KNS42 CCLE Cell Line Gene CNV Profiles -1.0 -1.52094 H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.962408 Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_474_KO_HDLBP_SRP261899 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.07263 CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null L428 CCLE Cell Line Gene CNV Profiles -1.0 -1.38536 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -1.53187 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01189 Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.901297 hsa-miR-3177-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_98_KD_INTS8_SRP262320 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.58766 Acute Myeloid Leukemia_LAML_TCGA-AB-2816-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3522_KD_CNOT1_SRP337789 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.50441 H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.27882 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.90863 hsa-miR-485-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 fallopian tube HPA Tissue Protein Expression Profiles 1.0 1.15606 Perturb_12148_OE_CENPA_ERP125655 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.07076 Perturb_444_KD_AKR1B1_SRP121474 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.66659 CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.56354 MM1S CCLE Cell Line Gene CNV Profiles -1.0 -2.66134 ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50327 CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9931_KD_TRA2A_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.68663 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07339 amygdaloid complex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.29946 dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38576 KMS11 CCLE Cell Line Gene CNV Profiles -1.0 -1.35088 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.87882 Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.967284 Perturb_7750_KD_POP1_SRP155278 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.17864 Perturb_8194_KD_SAFB2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.54979 u937 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.89123 JURKAT CCLE Cell Line Gene Expression Profiles -1.0 -1.88852 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4257_KD_AR_SRP184695 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.57442 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.30857 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17800_KO_FOXB1_SRP179665 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.77509 Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAPAN2 CCLE Cell Line Gene CNV Profiles -1.0 -1.8114 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null DEL COSMIC Cell Line Gene Mutation Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.831458 Perturb_8913_KO_KDM1A_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.19633 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3912_KD_Y14_SRP118481 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.78454 ZBTB7A ENCODE Transcription Factor Targets 1.0 null Perturb_12742_KD_GOT1_SRP282058 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.5601 Perturb_6706_KD_ELOA_SRP314942 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.2418 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.3886 Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05659 plicamycin_homo sapiens_gpl570_gse25127 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ACHN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.58047 Perturb_7912_KO_RNPC3_SRP367036 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.65293 UMRC2 CCLE Cell Line Gene Expression Profiles 1.0 1.41973 ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.938183 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26614 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.98059 HNT-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.991959 hsa-miR-541 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Perturb_6842_KD_RALY_SRP234429 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.2218 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.79229 OCI-AML3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.878769 JVM3 CCLE Cell Line Gene CNV Profiles 1.0 1.47109 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.91311 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS 38.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.913749 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14772 Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44011 Perturb_2906_OE_MACROH2A2_SRP333362 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.93361 CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15177_KD_CDH3_SRP366922 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.8454 Perturb_9399_KD_MYCN_SRP104120 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.19494 EBC1 CCLE Cell Line Gene CNV Profiles 1.0 2.0584 Perturb_6512_KD_ALKBH5_SRP090686 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.5228 Perturb_1992_OE_IRX5_SRP357294 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.6297 RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05423 Perturb_12370_OE_SNRPA1_SRP291347 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.81884 SKNAS CCLE Cell Line Gene CNV Profiles 1.0 1.66917 CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.85673 Perturb_9961_KD_YTHDC2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.78579 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07217 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58546 FOXP2 ENCODE Transcription Factor Targets 1.0 null IGR37 CCLE Cell Line Gene CNV Profiles -1.0 -1.75418 H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LN382 DepMap CRISPR Gene Dependency 1.0 2.30045 SH10TC CCLE Cell Line Gene CNV Profiles -1.0 -1.56394 H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11524_KD_NRF2_SRP092641 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.8509 Perturb_18482_KD_DNMT1_SRP261597 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.90445 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36526 ST486 CCLE Cell Line Gene Expression Profiles 1.0 1.78551 wm115 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 H3K36me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75308 AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.16126 CCC5 DepMap CRISPR Gene Dependency 1.0 2.64239 Perturb_5630_KD_EWSFLI1_SRP340258 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.92411 striatum_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.46648 MCC13 DepMap CRISPR Gene Dependency 1.0 2.04681 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00935 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JHUEM7 DepMap CRISPR Gene Dependency 1.0 2.25076 CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_94_KD_B4GALNT1_SRP127547 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.97554 Perturb_5562_KO_MTSS1_SRP266832 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.46945 Perturb_2730_KD_BCL11A/MBNL1_SRP258724 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.00476 Perturb_15443_KD_MED25_SRP212208 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.40895 Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15423_KD_PXN_SRP199368 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.95286 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superior colliculus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08038 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_6104_OE_WSTF_SRP400122 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.48799 H3K4me1_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_9031_KD_FOSL1_SRP320789 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.45819 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923366 H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_11380_KD_GATA2_SRP178865 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.9233 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_14890_KO_H15_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.44486 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.10117 H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02287 u698 HPA Cell Line Gene Expression Profiles 1.0 2.11923 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.40318 piriform cortex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.945367 NCI-H1944 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.899512 KDM4A ENCODE Transcription Factor Targets 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2054_KD_CHERP_SRP354316 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.60815 REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.89326 Perturb_501_KD_TLR3/BRF1_SRP382324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.4955 sclc21h HPA Cell Line Gene Expression Profiles -1.0 -0.894171 Perturb_7853_KD_CCNF_SRP212181 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.04535 transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06261 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17939 km3 HPA Cell Line Gene Expression Profiles 1.0 1.22074 Perturb_13833_KD_RYK_SRP131789 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.19649 Perturb_10080_KD_IGF2BP3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.0186 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.897516 CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3563_KD_HMGA1_SRP299065 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.01889 mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.47246 POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMEL CCLE Cell Line Gene Expression Profiles 1.0 2.18214 Perturb_9899_KD_EIF3G_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.76618 Rectum adenocarcinoma_READ_TCGA-EI-6510-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_531_KD_NKX22_SRP234742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.77188 CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16003 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.06883 RAJI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.895289 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26A-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923366 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pancreas HPA Tissue Gene Expression Profiles -1.0 -1.01772 LC1SQSF CCLE Cell Line Gene Expression Profiles 1.0 1.79701 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NZOV9 DepMap CRISPR Gene Dependency 1.0 7.66649 RCOR1 ENCODE Transcription Factor Targets 1.0 null H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17479 H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lung_3f HPA Tissue Sample Gene Expression Profiles 1.0 0.8675 cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.995999 Perturb_13706_KD_SMARCA2_SRP247495 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.15068 hsa-miR-588 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.27776 Perturb_9914_KD_IGF2BP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.57181 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.91728 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.87882 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.73802 Perturb_8231_KD_PRPF4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.61508 Perturb_14373_KD_IGF2BP1_SRP150935 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.819 Perturb_8257_KD_RBM27_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.87091 thp1 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64639 LU99 CCLE Cell Line Gene CNV Profiles 1.0 1.57347 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11296 STAT1 ChEA Transcription Factor Targets 1.0 null H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.851425 Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NO36 DepMap CRISPR Gene Dependency 1.0 2.99922 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20665 MAZ ENCODE Transcription Factor Targets 1.0 null H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cilium movement GO Biological Process Annotations 2023 1.0 null C84 DepMap CRISPR Gene Dependency 1.0 2.19071 amygdaloid complex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.58763 MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.05716 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.28008 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FGFR3_KD_GSE41035_77_human_RT112 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_14253_KD_QKI_SRP272585 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.56493 arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08052 H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_14154_KD_RCOR1_SRP279638 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.3817 Perturb_3573_KD_JAB1_SRP222371 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 ovary HPA Tissue Gene Expression Profiles -1.0 -1.01772 OCI-LY-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50872 hsa-miR-4722-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Perturb_15555_KO_SLFN11_SRP327912 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.45304 Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17806_KO_ZNF675_SRP304971 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.43605 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3850_KD_AKAP12_SRP254561 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.02537 OVCAR-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.01419 HUH1 CCLE Cell Line Gene CNV Profiles 1.0 1.43823 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5215 Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3713_KO_PIWIL1_SRP188921 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.294 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.33988 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.852369 TC32 CCLE Cell Line Gene Expression Profiles 1.0 1.43816 Perturb_8193_KD_PPIL4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.26249 CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7496_KD_EFTUD2_SRP192094 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.8053 striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.73274 GA10 CCLE Cell Line Gene Expression Profiles 1.0 1.60294 POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16143 SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.929423 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.997795 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.08015 CTCF ENCODE Transcription Factor Targets 1.0 null NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.98229 EZH2 ENCODE Transcription Factor Targets 1.0 null IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15379 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12958 H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8375 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.98434 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF384 ENCODE Transcription Factor Targets 1.0 null NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26477 rh30 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.905868 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.831458 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03748 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null lung_3e HPA Tissue Sample Gene Expression Profiles 1.0 1.2863 Perturb_9929_KD_TARDBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.55907 H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.27538 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.42429 Perturb_1087_KD_TBK1_SRP371732 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.38074 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.10412 H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_10035_KD_PUM1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.60555 CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KOPN8 CCLE Cell Line Gene Expression Profiles 1.0 1.85082 Perturb_17803_KO_ZNF675_SRP305529 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.63663 Perturb_7424_KD_CPSF2_SRP045481 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.7599 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.45484 VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28353 NCI-H2369 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.73486 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41914 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2854-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stomach_3b HPA Tissue Sample Gene Expression Profiles 1.0 1.04825 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.06616 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.900508 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DU4475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961286 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69327 Perturb_9925_KD_RBM34_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.68333 KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13281 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11296 NZM42 DepMap CRISPR Gene Dependency 1.0 8.58426 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05586 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.913645 Perturb_3711_KO_PIWIL1_SRP188921 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.58917 medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.968097 RFX5 ENCODE Transcription Factor Targets 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.907612 inner dynein arm assembly GO Biological Process Annotations 2023 1.0 null Perturb_10097_KD_CNOT8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.24004 striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0311 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4688 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8242_KD_SRSF7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.38214 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924367 Perturb_9973_KD_CSTF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.78462 Perturb_9106_KD_SNHG12_SRP223778 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.56198 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.845509 organelle LOCATE Predicted Protein Localization Annotations 1.0 null mediodorsal nucleus of thalamus_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.954607 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.82785 SKLU1 CCLE Cell Line Gene CNV Profiles 1.0 1.46628 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.84738 Perturb_7383_KO_SMG7_ERP122822 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.3805 FOXP2_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12846 CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MI-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hel HPA Cell Line Gene Expression Profiles -1.0 -0.894171 H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_2291_OE_TBX3_SRP184219 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.5787 Perturb_9919_KD_MATR3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.50057 Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.42853 Perturb_4904_KO_NSUN6_SRP233222 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null bronchus HPA Tissue Protein Expression Profiles 1.0 1.15606 H3K4me1_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null anterior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.903398 Perturb_9910_KD_CIRBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.96584 RFX1 MotifMap Predicted Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15403_KD_AR_SRP377764 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_9130_KD_PHGDH_ERP020769 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.99711 Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11173 Perturb_14021_OE_MIR722_SRP185837 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05714 hippocampus (hippocampal formation)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1164 JUND ENCODE Transcription Factor Targets 1.0 null MM160113 DepMap CRISPR Gene Dependency 1.0 2.79043 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60798 striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.25938 Perturb_9632_KD_CHD8_SRP047233 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.99681 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.40398 8505C COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_2986_KO_BAP1_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.695 NR3C1 ChEA Transcription Factor Targets 1.0 null Perturb_8059_KD_IGF2BP3_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.71055 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.93723 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2797_KD_RORC_SRP066204 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.31385 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.875963 POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2392_KD_TRIM28_SRP308699 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ECC10 CCLE Cell Line Gene CNV Profiles -1.0 -2.10996 RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null Perturb_8197_KD_TRIM56_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.97018 ZBTB7A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS153 CCLE Cell Line Gene CNV Profiles 1.0 1.79701 Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15515_KD_E2F2_SRP314859 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.60823 Perturb_7155_KD_ARID1A_SRP366384 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.55463 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T3M5 DepMap CRISPR Gene Dependency 1.0 3.8513 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61282 Perturb_13496_KD_IGF2BP1_SRP252425 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.96806 HGC27 CCLE Cell Line Gene CNV Profiles -1.0 -1.55594 VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.976047 SHSY5Y CCLE Cell Line Gene Expression Profiles -1.0 -2.1634 BCPAP CCLE Cell Line Gene Expression Profiles -1.0 -2.45423 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09699 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7159_KD_ACTG1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.66484 motile cilium GO Cellular Component Annotations 2023 1.0 null RERFLCAD2 CCLE Cell Line Gene CNV Profiles -1.0 -1.34829 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.3374 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975756 granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20042 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39503 Perturb_448_KO_RPA_SRP158719 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.36535 Perturb_12971_KD_GATA3_SRP372594 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.94886 Perturb_9926_KD_SRSF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.0775 SK-MEL-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null CORL24 CCLE Cell Line Gene Expression Profiles -1.0 -2.04118 Perturb_9821_KD_MYB_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.21725 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36152 Perturb_15021_KD_RelA_SRP078053 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.7419 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44159 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6698_KD_ALAL1_SRP214241 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.35722 IGR39 CCLE Cell Line Gene CNV Profiles -1.0 -1.52971 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.918431 ICC2 DepMap CRISPR Gene Dependency 1.0 2.61692 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.24031 CL-40 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50872 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.892166 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.897516 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null QGP1 CCLE Cell Line Gene CNV Profiles -1.0 -2.08755 OVMANA CCLE Cell Line Gene Expression Profiles 1.0 1.9671 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_7498_KO_USP10_SRP192777 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.126 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22886 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.863563 Perturb_8076_KD_AGO1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.2723 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26599 ANGMCSS DepMap CRISPR Gene Dependency 1.0 3.80898 cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.31888 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.02366 Perturb_2148_OE_RKIP_SRP189735 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.14408 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20353 striatum_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.943811 SCS214 DepMap CRISPR Gene Dependency 1.0 4.23695 Perturb_8759_KO_SETDB1_SRP141213 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.2995 Perturb_14624_KD_GOT1_SRP282058 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.5229 H3K4me1_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null A704 CCLE Cell Line Gene CNV Profiles 1.0 1.43089 Perturb_9372_KO_PRDM15_SRP288370 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.56614 NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.867623 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4896_KD_NCBP1_SRP160510 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.60929 Perturb_7776_KD_C1QTNF1AS1_ERP112231 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.75661 Acute Myeloid Leukemia_LAML_TCGA-AB-2875-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8822_KD_TRRAP_SRP106050 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.34996 Perturb_9032_KD_FOSL1/FOSL2_SRP320789 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.87005 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_14202_KD_KLF5_ERP117894 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.93998 CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.897376 Perturb_9987_KD_TARDBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.69764 Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.30459 Perturb_7388_KO|KD_UPF3B|UPF3A_ERP130413 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.8861 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.48724 amygdaloid complex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14096 H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844553 hsa-miR-4701-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53297 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.56383 deep layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20422 Perturb_14127_KO_TP53/CDKN2A/PTEN/NF1_SRP258861 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.50091 Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SET2 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-1291 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.987808 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02082 MDAMB361 DepMap CRISPR Gene Dependency 1.0 7.07471 SUP-HD1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUO9 DepMap CRISPR Gene Dependency 1.0 2.7422 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null skmel30 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TUHR10TKB CCLE Cell Line Gene Expression Profiles -1.0 -1.71396 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30464 WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.00761 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.51757 daudi HPA Cell Line Gene Expression Profiles 1.0 1.17589 Perturb_4368_KO_Peg10_SRP167954 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.65997 Perturb_8867_KD_PNN_SRP063860 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.4741 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.45527 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18889 T3M4 CCLE Cell Line Gene Expression Profiles 1.0 1.61865 H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-654-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.63904 Perturb_8185_KD_DNAJC2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.53404 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26281 SHMAC4 DepMap CRISPR Gene Dependency 1.0 3.26801 LOVO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20992 Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT1-20625510-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_644_OE_ERG_SRP344038 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.67673 BICR16 CCLE Cell Line Gene Expression Profiles 1.0 1.53483 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.079 KASUMI1 CCLE Cell Line Gene Expression Profiles 1.0 1.89631 HDQP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.53052 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07959 ZBTB7A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5784-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15699_KD_PARP1_SRP280274 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 EGR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.885925 CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5479-01A-31R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.23102 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.931634 Perturb_15391_KD_CHD6_SRP399677 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.74953 SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.80941 ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS863T CCLE Cell Line Gene Expression Profiles -1.0 -1.87061 caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.862323 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01378 NCIH1155 CCLE Cell Line Gene Expression Profiles -1.0 -1.5681 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.41565 Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7387_KO_UPF3B_ERP130413 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.25209 PANC0327 CCLE Cell Line Gene CNV Profiles -1.0 -1.70671 anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.989317 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.978652 H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CORL105 DepMap CRISPR Gene Dependency 1.0 2.35577 JHH-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.938025 HS 675.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.50625 H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.995048 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0178 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37046 SNU869 CCLE Cell Line Gene Expression Profiles 1.0 3.40796 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH2004RT DepMap CRISPR Gene Dependency 1.0 2.23425 Perturb_7306_KD_IER3_SRP348787 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.8229 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.87871 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37882 Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8914_KO_KDM1A_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.3358 hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.66665 hsa-miR-4314 TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 NCIH1355 CCLE Cell Line Gene CNV Profiles 1.0 2.16552 MYC ENCODE Transcription Factor Targets 1.0 null CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 2.10203 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H4K20me1_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.28243 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0552 Perturb_17807_KO_ZNF675_SRP304971 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.63663 H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.05402 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Perturb_12666_OE_GFP_SRP308919 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.90621 H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.03224 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.01542 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2078_OE_PUM2_SRP072710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.81879 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL851 CCLE Cell Line Gene Expression Profiles 1.0 1.35505 EGR1 ENCODE Transcription Factor Targets 1.0 null Perturb_9918_KD_MAGOH_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.81808 posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.847683 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA ChEA Transcription Factor Targets 2022 1.0 null central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.90576 Perturb_14187_KD_RUNX1_SRP159178 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.59515 Perturb_6420_KD_SPRY4IT1_SRP347515 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.14247 KDM5B ENCODE Transcription Factor Targets 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.70064 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.44377 MAPACHS77 DepMap CRISPR Gene Dependency 1.0 2.00154 parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42135 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null fallopiantube_8c HPA Tissue Sample Gene Expression Profiles 1.0 1.91669 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17271 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924367 CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.42958 hsa-miR-3192 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 T3M4 CCLE Cell Line Gene CNV Profiles 1.0 1.46276 CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11296 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.34458 MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -1.63766 Perturb_8110_KD_NAA15_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.30661 Perturb_8998_KD_lnc Cyrano_SRP261325 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.60275 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17844 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11296 Perturb_5173_KD_Hnrnpk_SRP078486 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.45712 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null axonemal dynein complex assembly GO Biological Process Annotations 2023 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MOLT-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37159 spermatid development GO Biological Process Annotations 2023 1.0 null SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3753 BECKER CCLE Cell Line Gene Expression Profiles -1.0 -2.00811 CA2 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.831847 NALM-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15779 Perturb_9933_KD_AKAP8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.41318 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976787 Perturb_10674_KD_PLAG1_SRP332281 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.9959 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01743 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10538 SKNFI CCLE Cell Line Gene CNV Profiles 1.0 1.38035 SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14772 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13274 Perturb_10017_KD_LARP7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.91808 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.981484 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null KP2 CCLE Cell Line Gene CNV Profiles -1.0 -1.41676 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18721 amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.929988 Perturb_14161_KD_BZW1/BZW2_SRP316321 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.2761 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEP3B217 CCLE Cell Line Gene Expression Profiles 1.0 1.67102 CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18234 pyramidal layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.847321 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6829 ISHIKAWA(HERAKLIO)02ER- COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_8195_KD_SMN1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.20164 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30475 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null fallopiantube_8d HPA Tissue Sample Gene Expression Profiles 1.0 2.11246 DOR 13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.90513 CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17282_KO_Hsf5_SRP345601 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 BHT101 DepMap CRISPR Gene Dependency 1.0 2.62405 NCIH2106 CCLE Cell Line Gene CNV Profiles -1.0 -1.59996 Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00843 HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58546 Perturb_8093_KD_PUM1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.37279 cuneus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42173 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.897512 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.978491 CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.44555 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985478 Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUPT11 CCLE Cell Line Gene CNV Profiles -1.0 -2.15385 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null Perturb_11562_KD_BAX/BAK_SRP348085 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_15573_KD_NUSAP1_SRP074246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.76665 Perturb_2607_KD_lncSNHG7_SRP179047 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.45887 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_9862_KO_MYB_SRP192629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.31279 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.22203 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.916364 Perturb_449_KO_RPA_SRP158719 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.21819 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.39641 HN COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH3122 DepMap CRISPR Gene Dependency 1.0 3.06829 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21677 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.54842 fallopiantube_8e HPA Tissue Sample Gene Expression Profiles 1.0 1.33803 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HMCB CCLE Cell Line Gene Expression Profiles -1.0 -1.50365 NALM16 DepMap CRISPR Gene Dependency 1.0 2.51767 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.61556 Perturb_7161_KD_CD81_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.55348 RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LC1F CCLE Cell Line Gene Expression Profiles 1.0 1.75436 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_452_OE_MYC_SRP171977 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.5317 cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.7855 Perturb_9915_KD_IGF2BP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.2513 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18889 Perturb_13687_KD_ATG5_ERP127841 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.2022 RPMI 2650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.29859 MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.59363 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.934713 HDAC2 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC1 ENCODE Transcription Factor Targets 1.0 null Perturb_7163_KD_CD81_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.69252 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.952697 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.974119 Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -2.0876 PHF8 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JIYOYEP-2003 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COLO 849 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06166 H2BK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_2628_OE_HPGD_SRP292282 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.5672 Perturb_2937_KD_Ddx1_SRP237952 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16003 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-892a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.923377 L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05492 KCL22 CCLE Cell Line Gene Expression Profiles -1.0 -1.46196 PSN1 CCLE Cell Line Gene Expression Profiles -1.0 -1.74343 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11448 medial geniculate nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877391 TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G402 DepMap CRISPR Gene Dependency 1.0 2.76628 H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_10699_KD_CD274_SRP307356 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.87461 Perturb_14068_KD_ALKBH5_SRP247667 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.99114 Perturb_8916_KO_KDM1A2a_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.4402 PSS008 DepMap CRISPR Gene Dependency 1.0 8.52355 Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844553 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.0678 Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8031_KD_PURPL_SRP383476 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.53061 Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27064 lateral dorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855439 CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9935_KD_ATP5F1C_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.05992 Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3749_KD_NORAD_SRP149071 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.91831 Perturb_7705_KD_YTHDF1/YTHDF2/YTHDF3_SRP214946 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.40717 Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7883_KD_UPF1_SRP267244 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.25742 HSC4 DepMap CRISPR Gene Dependency 1.0 2.21295 Perturb_14375_KD_IGF2BP1_SRP291710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.819 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.912839 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.45902 Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.28627 Sarcoma_SARC_TCGA-DX-A23V-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11736_OE_KLF5_SRP091857 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_16609_KO_Larp7_SRP189392 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.44579 TC-71 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.41216 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.11388 Perturb_11949_KD_NRF2_SRP092641 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_14561_KD_UBE2C_SRP221206 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.58064 Perturb_9958_KD_SUGP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.70907 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9892_KD_PPIG_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.53874 H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2734_KD_BCKDK_SRP298085 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.41453 Perturb_3894_KO_Lonp1_SRP301760 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.92448 Perturb_482_KD_IFI16_SRP298943 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.66888 inferior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03982 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.897941 dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.93429 Perturb_12232_KD_SNRPA1_SRP291357 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.9348 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.868526 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CHD1_02_187 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.62803 NCIH1436 CCLE Cell Line Gene Expression Profiles -1.0 -1.50903 CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB134VI CCLE Cell Line Gene CNV Profiles 1.0 1.68577 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2420_KD_DDX3X_ERP105312 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.48253 H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.16038 Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1 ENCODE Transcription Factor Targets 1.0 null magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.984124 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5102-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5204 CDK4_knockdown_143_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.59859 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17802_KO_ZNF675_SRP305529 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.43605 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.45702 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-922 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Perturb_12576_KO_NOTCH1_SRP143456 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.50602 primary auditory cortex (core)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.889767 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2803_KO_CDH1_SRP267080 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.01615 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GAMG CCLE Cell Line Gene Expression Profiles -1.0 -1.64731 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO668 CCLE Cell Line Gene CNV Profiles 1.0 2.24926 Perturb_7314_KO|KD_UPF3A_ERP130416 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.19848 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.05394 H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29974 body of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26684 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-339-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17089 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_764_KD_SRRM2_SRP366559 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.02283 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.57491 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39043 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.75149 Perturb_9406_KD_GATA6AS_SRP279802 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.55859 CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACHN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.916685 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05081 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848384 fulvestrant_homo sapiens_gpl570_gse22533 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BACH1 ENCODE Transcription Factor Targets 1.0 null Perturb_11445_KD_GATA2_SRP178865 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.52497 Perturb_8712_KD_SHQ1_SRP154234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.91637 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9923_KD_PTBP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.88395 SKMEL24 CCLE Cell Line Gene Expression Profiles -1.0 -2.69622 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1106 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral anterior nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09452 Perturb_9921_KD_PCBP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.54542 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7290_KD_CNOT1_SRP099077 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.89858 FOXA1_OE_GDS4957_10_human_LNCaP prostate cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_15452_KD_circCSNK1G3_SRP139940 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.74544 septal nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0244 LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.49098 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TC71 CCLE Cell Line Gene CNV Profiles -1.0 -2.7709 Perturb_15405_KD_NRP2_SRP377764 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 hsa-miR-4693-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 BT16 DepMap CRISPR Gene Dependency 1.0 3.02722 CTCF_MCF-7_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26477 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.835452 Perturb_4011_KD_SMAD3_SRP149729 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.17836 CTCF_GM12868_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cilium GO Cellular Component Annotations 2023 1.0 null Perturb_4378_KD_MALT1_SRP127318 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.83457 Perturb_8258_KD_RCC2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.07212 lung GTEx Tissue Gene Expression Profiles 1.0 1.04298 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12147 MAPK1_knockdown_145_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.94172 Perturb_9972_KD_BCLAF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.78397 KM12 CCLE Cell Line Gene CNV Profiles 1.0 1.43312 Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.44796 Perturb_3893_KO_Lonp1_SRP301760 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.54164 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.991903 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_13927_OE_ESRRG_SRP363188 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.31349 MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW1990 DepMap CRISPR Gene Dependency 1.0 2.64225 H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.978083 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05659 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36686 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.3053 Perturb_11936_KD_SMARCD1_ERP132117 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.38192 ICC4 DepMap CRISPR Gene Dependency 1.0 2.37087 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08029 hsa-miR-2276 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Perturb_599_OE_HOTAIR_SRP342161 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.9879 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.21094 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.45041 Perturb_7154_OE_MOV10_SRP029367 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.25427 Perturb_7708_KD_Spt6_SRP132004 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.97344 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.2647 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.906617 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.948451 RBBP5 ENCODE Transcription Factor Targets 1.0 null Perturb_2422_KD_DDX54_ERP105312 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.86448 Perturb_13834_KD_RYK_SRP131789 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.05646 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53384 Rectum adenocarcinoma_READ_TCGA-AH-6544-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nasopharynx HPA Tissue Protein Expression Profiles 1.0 1.15606 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.19599 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15816 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.914711 Perturb_2575_KD_LINE1_ERP011233 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.77531 TEAD4 ENCODE Transcription Factor Targets 1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31238 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11663 Perturb_7547_KO_CNOT1_SRP282906 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.90295 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.84389 LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.913645 ventrolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.850364 SNU878 CCLE Cell Line Gene Expression Profiles 1.0 2.57871 Perturb_13680_KD_KDM3B_SRP221048 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.54682 primary auditory cortex (core)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01838 Perturb_500_KD_RL6/BRF1_SRP382324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.73009 primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.839772 EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50872 hsa-miR-4433 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32924 fallopian tube HPA Tissue Gene Expression Profiles 1.0 1.94066 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04386 T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11296 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21842 H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.15777 SP in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26993 cervix uteri GTEx Tissue Gene Expression Profiles 1.0 0.899128 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_4263_KO_OTX2_SRP388433 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.2313 Perturb_12108_KD_CCND1_SRP244245 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.8545 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11296 lung HPA Tissue Gene Expression Profiles 1.0 0.991539 muscle GTEx Tissue Gene Expression Profiles -1.0 -1.26841 Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20665 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844553 Perturb_6755_KO_UPF3A/UPF3B_SRP327782 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.0945 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.845654 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.98561 inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06223 RAD21 ENCODE Transcription Factor Targets 1.0 null SNRK_overexpression_127_GSE30185 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -3.03722 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30447 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN45 CCLE Cell Line Gene CNV Profiles -1.0 -1.85853 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06686 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.845654 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10044 NCI-H2085 COSMIC Cell Line Gene Mutation Profiles 1.0 null MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.845654 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null golgi apparatus LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_11927_KD_SMARCB1_SRP127642 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.1652 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882825 HCC44 CCLE Cell Line Gene Expression Profiles 1.0 2.37017 HLE CCLE Cell Line Gene Expression Profiles 1.0 1.68164 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1641 Perturb_11952_OE_MYC_SRP355809 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNUC1 DepMap CRISPR Gene Dependency 1.0 4.89413 CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2294_KD_DDX5_SRP139509 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.66455 H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_13251_KO_Dux_SRP098643 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.45409 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9941_KD_MBNL1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.05457 Perturb_7597_KO_TENT3A/TENT3B_SRP400572 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.5172 CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844553 Perturb_9930_KD_TIA1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.5985 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.999883 HPAFII CCLE Cell Line Gene CNV Profiles 1.0 1.83911 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SKM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.2604 Perturb_8212_KD_SMNDC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.94291 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04544 CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.934713 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.843487 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870541 NR3C1-21868756-MCF10A-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_11402_KD_CPT1A_SRP076884 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.00602 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05546 Perturb_14376_KD_MECOM_SRP276625 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.67659 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892396 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26477 stomach HPA Tissue Gene Expression Profiles 1.0 0.880874 Perturb_6828_KD_Xrn1_SRP148176 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.89366 fallopiantube_5a HPA Tissue Sample Gene Expression Profiles 1.0 1.30859 TTC549 DepMap CRISPR Gene Dependency 1.0 11.0036 Perturb_9932_KD_AGGF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.5897 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36539 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.845654 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K23me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.02163 Perturb_17616_OE_FOXP2_SRP225889 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.10204 ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H4K20me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null CDK2_knockdown_146_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.60975 SUM185PE DepMap CRISPR Gene Dependency 1.0 2.86506 Perturb_2543_KD_SNHG7_SRP179498 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.07981 fallopiantube_8b HPA Tissue Sample Gene Expression Profiles 1.0 1.01166 primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.27452 Perturb_7631_KD_AF4_SRP078067 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.33893 Perturb_2518_KD_ZNF414_SRP269946 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.50127 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.21488 Perturb_7356_KO_NSUN6_SRP233222 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.15948 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.47491 hsa-miR-550a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.88124 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.01657 CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.10833