association	dataset	threshold value	standardized value
BRD-K49473928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31364
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14615
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K88746179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09994
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9101
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
BRD-K02100640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14298
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199606_3_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.163
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
HFL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
C57MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
BRD-K30318008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6141
BRD-K25127909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76883
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6979
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.122
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_42_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7144
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_13_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4263
CL1-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
Esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
GSE184087_0_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46248
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Tibia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
Tendon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.889
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6296
BRD-K27719710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24212
BRD-K43057855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09252
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.79695
GSE144346_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Synovia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_24_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87530935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02694
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77554
GSE210225_0_v_1_inosine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02385
CASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09465
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K00877314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50436
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
GSE235701,GSE261434_2_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_39_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12370121-pone.0329101.s003.pdf-1-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9081
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0232
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Alveolar wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86452
BRD-K45222498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50294
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
Epiphysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
BRD-M01343043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00463
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.45868
BRD-K69152679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05846
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Integrin alpha10-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.099
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_78_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15794956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46988
Graves' disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_57_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12446642-mmc1.xlsx-Table_S6_Overlap_MR5E-8-Supplementary_Table6_Overlap_between_Cox_associated_proteins_and_MR-positive_proteins_with_a_MR_SNP-P_threshold_of_5E-8_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30895360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17083
Chorioallantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Upregulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.527
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3978
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38984040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11707
Hepatic stellate cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0969
BMP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3143
BRD-K15591233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39972
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_63_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Complex of collagen trimers	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.138
Integrin alphav-beta5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.877
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
insulin-like growth factor binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.287
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-LEUTX_UP-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_up_to_an_FPKM_of_at_least_2_LEUTX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73808079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19685
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14203360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26422
Bile duct carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
External encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.59
GSE104508_0_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Calvarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.383
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rheumatoid arthritis disease specific synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
GSE217405_3_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36460068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01291
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31233830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91526
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Coronary atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.923
BRD-K95761590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31225
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70499_4_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07963
BRD-K21000135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35234
Parenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12781
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_9_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic ductal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
Endogenous progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59484021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21088
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.869
BRD-K07460436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3999
BRD-K12132610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69023
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
BRD-K84707727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78176
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4438
BRD-K18077898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.75238
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87385385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26903
BRD-K13927197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1412
BRD-A66164310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44963
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22038
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
C81-61 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.955
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_27_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7304
PMC10891378-tau-13-01-91-supplementary.pdf-50-PURA_PURA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83095019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52536
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EL-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42963
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_60_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13377
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.154
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A44068497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28635
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.888
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.04658
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Integrin alpha11-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-Suppl_Table_6_DEG-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K11730256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10719
BRD-K28952606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40926
BRD-K79995507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17371
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Meloxicam_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0107289
Bone matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.626
GSE167324_1_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
APEH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K44062658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38562
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17547
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	211.438
BRD-K80733946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38016
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0847
GSE204832_0_v_1_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67399222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61219
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166004_3_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03141963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65705
BRD-K54785691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16003
BRD-K83028309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74346
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE261563_5_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09863466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07694
BRD-K28623804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63086
BRD-K72351789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11135
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7128
PMC11634769-44161_2024_567_MOESM3_ESM.xlsx-ST_7-Supplementary_Table_7_F-statistics_and_Rē_estimates_for_the_genetic_instruments_tested_in_cis-Mendelian_randomization_MR_analyes_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2291
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.954
Prostate	GTEx Tissue Gene Expression Profiles 2023	1.0	6.17309
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184892_7_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_16_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6996923-elife-46981-supp4.xlsx-KO_Up_Only_Vs_OCT4-Column_ID_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder papillary transitional cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
Laryngeal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
BRD-A45607610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28864
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10105458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41389
Laryngeal squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
LNCaP-C4-2B4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
VEGF-A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.895
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9443
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_264_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48239
GSE199034_1_v_0_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VB-89-RG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340554
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60014
Extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Osteosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
chr8_133190246_A_G_b38	GTEx eQTL 2025	1.0	1.80107
BRD-K07734771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27714
PMC5323140-oncotarget-07-65090-s002.xlsx-DUX4_DUX4c-Gene_symbol_db2db_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
fibro-adipogenic progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.751
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.083
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
BRD-K01237277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03012
Growth factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.219
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04422
BRD-K41025232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37883
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65202
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24125966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48036
positive regulation of osteoblast differentiation	GO Biological Process Annotations 2025	1.0	null
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68749
Breast epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.44
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17502
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226983_1_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Abdominal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.381
PMC10319848-mmc1.pdf-3-PRRX2_PRRX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100102_4_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134896_0_v_7_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
Skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.69
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.321
BRD-K06208863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25298
Adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9655
BRD-K53456628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02479
BRD-A98099470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6614
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K57167256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11793
GSE100102_4_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hair follicle bulge stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
low-density lipoprotein receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.2
BRD-K87743988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32724
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Renal fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.836
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Clotrimazole_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0304644
BRD-A62787624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2457
GSE132313_1_v_0_fosl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE252857_2_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.65145
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastric adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
adipose-derived stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
C19orf73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67323
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.834
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K53889798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06611
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
GSE89018_1_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K07496812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21453
BRD-K77490065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63045
Alveolar sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.611
Interstitial lung disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.016
Urinary tract papillary transitional cell benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
CRCGN014_HEPG2_3H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0096
Mammary ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65836281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09312
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24382357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1536
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0577
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50127933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74171
BRD-K82784817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07612
Periosteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.23
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
Adult liver stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3258
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4944
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33318
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78477132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3161
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
BRD-K36465335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88976
positive regulation of developmental process	GO Biological Process Annotations 2025	1.0	null
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03435
Extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.614
Activin AB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.058
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.792
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.365
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7982
BRD-K53783288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03052
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73951
BRD-K33128056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20826
BRD-K15997423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2602
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8507
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	172.87
BRD-K94441949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75116
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0764
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52985
BRD-K15433418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30925
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.469
PMC8791933-41598_2022_4817_MOESM4_ESM.xlsx-PAX7_down-Unnamed_1_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8822763-13293_2022_415_MOESM3_ESM.xlsx-ML_MR_DEG-Gene_name_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68435627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30399
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Endothelial progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
Intramuscular adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
Synovial tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Fibronectin fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
PMC4453609-bjc2014560x10.xls-Sheet1-HCT116_SMAD4_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5606
PMC11634769-44161_2024_567_MOESM3_ESM.xlsx-ST_8-Supplementary_Table_8_Steiger_filtering_results_for_protein-disease_pairs_tested_in_sensitivity_cis-Mendelian_randomization_MR_analyses_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Pleomorphic adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
PMC11485038-384_2024_4744_MOESM1_ESM.xlsx-Sheet3-Supplementary_Table3_Unique_leader_cis-pQTLs_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-fig-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68216590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05927
BRD-K48092898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66262
BRD-K09511124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91461
Female reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
BRD-K03353688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51644
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pentoxifylline_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0202718
PMC8700172__F1	PFOCR Pathway Figure Associations 2024	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33775409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48058
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0605
PMC12631116-ijbsv21p6674s5.csv--Differential_analysis_of_RNA-Seq_data_in_HCT116-ETV4_cells_combined_with_correlation_analysis_of_LOXL2_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Esophageal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K48593237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6739
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1484
BRD-K55869732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.13153
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5365
BRD-K22002184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8051
BRD-K34556006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16356
Annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.84558
BRD-K69678391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97804
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
BRD-K40219231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76027
BRD-K60080002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0704
GSE70499_4_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bile duct cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
ATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69133
BRD-K98941192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33036
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Osteogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.231
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17983
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K35085740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79605
BRD-K35978846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86159
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29831
Oral squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
GSE139325_2_v_3_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11223
Osteosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NRK-49F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
MRC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune thyroiditis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.365
BRD-K49742819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12163
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38046923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02494
BRD-K09903493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70023
Chorionic plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
GSE203308_8_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146865,GSE146866_4_v_3_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Integrin alpha7-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_6_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154081_1_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04358482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38951
Th-1 cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_9-Table_9_The_association_of_genetically_predicted_levels_of_proteins_with_the_risk_of_coronary_heart_disease_CHD_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Enamel epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	147.115
BRD-K59560948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24261
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.113
BRD-K87073572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3743
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
BRD-A06840811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99706
Intracellular anatomical structure	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.229
Bone sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.693
Mycolate outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
Dermal fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.575
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE247862,GSE247863_4_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K99198579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26119
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Orlistat_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0137263
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_54_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF285	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49043
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S23-Table_S23_MR_resluts_of_blood_proteins_in_AGES_project_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11732233-mmc1.pdf-166-FOSL2_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
MYD88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77831
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-253 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
GALNT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84871
TJP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95041
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.987
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5545
Pasireotide (acetate)_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.020931
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
Synovium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.787
regulation of cytokine production	GO Biological Process Annotations 2025	1.0	null
BRD-K25583354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30864
PMC11956947-media-4.xlsx-C_GSEA_gene_sets-TGAYRTCA_ATF3_Q6_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12169
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.03231
Pronephros	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.3304
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_12_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7089
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
BRD-K23585987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.47983
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49981566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26795
Chondrocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
BRD-K66282601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27269
Prostate gland stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1888
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
PMC12446642-mmc1.xlsx-Table_S7_Overlap_MR1E-5-Supplementary_Table7_Overlap_between_Cox_associated_proteins_and_MR-positive_proteins_with_a_MR_SNP-P_threshold_of_1E-5_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6366065-13075_2019_1816_MOESM1_ESM.xlsx-DOD_Skin_imputed_log2_median_ce-Name_PIN1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79395
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Synovial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
Wnt signaling pathway	KEGG Pathways 2026	1.0	null
G43417UB	GlyGen Glycosylated Proteins	1.0	null
PMC11582803-41598_2024_80483_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_MR_analysis_of_Proteome_wide_Mendelian_Randomization_FinnGen_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86677819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08039
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5003
Lobular carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
Budesonide_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.027889
BRD-K97486995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2377
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K49635910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00824
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
Elagolix sodium_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0130456
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.8576
catenin-TCF7L2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.935
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.68491
GSE255680_1_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4559
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10299
BRD-K77953978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57695
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16915521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.02431
Integrin alpha5-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.82
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	193.273
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.986
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8624
BRD-K08247496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26389
BRD-K48308783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38968
GSE110268_0_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30288714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41144
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stellate cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
Bile duct adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4843
BRD-K56469794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.45186
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251608
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Chondrogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MC3T3-E1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.176
BRD-K92910000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55591
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-33-BM51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204698
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93662118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37466
Elastic fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.235
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80115
interleukin-23 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
GSE142210_3_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K55399138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.9648
positive regulation of cellular process	GO Biological Process Annotations 2025	1.0	null
BRD-K62800316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.89253
BRD-K36961619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01556
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66098
BRD-K44521151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31388
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
BRD-K06956443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23488
BRD-K06935782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42373
GSE233566_1_v_2_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Subcutis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87082948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24735
Femur bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K21969044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31964
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80409
GSE171826_1_v_0_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Renal proximal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3502
BRD-K75588273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04866
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
BRD-K32084247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43465
BRD-K98153780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28906
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8236
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7076
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Large latent transforming growth factor-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
BRD-K26826253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64714
GSE87404,GSE87812_2_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
Bimatoprost_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.020767
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7062
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Integrin alpha4-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.374
BRD-K84077642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
beta-catenin destruction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.877
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_12_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96271
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4060771-170289.f1.pdf-637-SMAD1_SMAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11565774-media-1.xlsx-ST20-Olink_protein-CHIP_MR-Supplemental_Table_20_Genetic_causal_relationship_of_proteins_on_CHIP_variables_for_CHIP-proteomic_pairs_with_FDR_0_05_in_UK_Biobank_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14169
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6591464-Table_4.xlsx-Sheet_1-AIRE_regulated_genes_TRA_annotated_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47878187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01426
Nonparenchymal liver cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rough endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.129
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1577
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18768
PMC12152148-41420_2025_2541_MOESM3_ESM.xlsx-AR-IP-DHT_peak-gene-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
BRD-A06837695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42205
PMC8687553-pone.0261191.s009.xlsx-KLF4-related-Unnamed_0_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07589203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30423
BRD-K15343767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19853
BRD-A11130173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19328
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.876
Atrioventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
Squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
BRD-K73355908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07814
Integrin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.224
Osteocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.917
BRD-K88543505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74814
Activin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.381
PMC11110418-12864_2024_10412_MOESM1_ESM.xlsx-S_Table_2-Supplementary_Table_2_Detailes_of_the_instrumental_variables_of_plasma_proteins_used_in_discovery_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74847
BRD-K52017042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06193
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54003455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14621
BRD-A99445203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29613
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.5652
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45519638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65546
Long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.398
PMC4728380-ncomms10153-s8.xlsx-MYC_binding_intensity_ALL-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE255680_1_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1151
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Adhesive extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87622
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.73195
BRD-K75672292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46836
M1 macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
BRD-K59821747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00374
Bone marrow stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0867
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_33_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153010_1_v_0_sprr2f_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
Marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
GSE186654_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4103
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
PMC9334849-Table_3.xlsx-subcutaneous_adipose_tissue-D1_VS_D9_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.858
PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_11-Table_11_The_association_of_genetically_predicted_levels_of_proteins_with_the_risk_of_HF_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100511_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44241
GSE100102_0_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
BRD-K24020784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02376
GSE248668_1_v_0_atxn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesenchymal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.036
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32813
GSE121198,GSE129779_0_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Endomysium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
PMC11459707-12890_2024_3289_MOESM1_ESM.xlsx-Table_S8_MR_results-Supplementary_Table8_The_causal_effect_of_proteins_on_IPF_risk_from_UK_Biobank_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BAX complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.362
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K59078549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37558
BRD-K47349869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15313
BRD-K07614312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1328
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Integrin alphav-beta8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38482
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A09961470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35214
BRD-K26402831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49485
osteoporosis-pseudoglioma syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
PMC11839199-CPR-58-e13746-s001.docx-4-OSR2_OSR2	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.391
olaparib_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0219202
Stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.916
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-364-CUX2_CUX2	Rummagene Transcription Factor Associations 2026	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8783
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4776
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_36_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0275
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K83670600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93279
BRD-K39267096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11599
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12345912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83741
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Left ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
BRD-K07870648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76781
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5202
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44052748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91398
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
Buccal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5854
GSE217694_3_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30865566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04745
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.89425
BRD-K93806272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41127
BRD-K84741596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45783
BRD-K45969405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57448
Leiomyoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
GSE128688_0_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
melan-a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8824
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35596700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9786
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K23029982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20633
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.872
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-ATF2_UP_V1_DN-Gene_name_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
Nephroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3319
BRD-K06166879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96081
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1034
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50704115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19221
Hepatic stellate cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.93183
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K92018859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.02684
BRD-K39159284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98347
BRD-K06729289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57572
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
BRD-K00218068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35206
Mhs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186287_1_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
BRD-K77845452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2233
BRD-K37719063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38446
GSE180789_1_v_0_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A44438286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.01583
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST18-Unnamed_2_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K90534988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68572
Bone marrow stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of cell differentiation	GO Biological Process Annotations 2025	1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.21759
BRD-K91973560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15872
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_8_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Myofibroblast_Ascending aorta_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BRD-A21814529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41007
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
BRD-K03886176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5333
GSE224311_3_v_0_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2461
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Periodontal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15378071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23513
BRD-K65361030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.52217
Glioma stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.476
Multimeric ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
BRD-K02159857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97834
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41444
BRD-K53458780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26127
PMC12529848-12967_2025_7217_MOESM3_ESM.xlsx-Table_S4-Table_S4_Associations_of_genetically_proxied_proteins_with_risk_of_atrial_fibrillation_by_MR-SPI_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3038
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PGM2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47571
Alveolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.612
Signal recognition particle receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.208
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5347
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2177
BRD-K11610091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68816
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77173942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85121
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bronchiolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
BRD-K10269761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70085
BRD-K05137000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28392
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2693
GSE100102_0_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.96763
Rheaume et al.Nat Commun.8_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
positive regulation of smooth muscle cell proliferation	GO Biological Process Annotations 2025	1.0	null
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
BRD-K30601921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56142
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226397_0_v_1_cystine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115363_2_v_0_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of smooth muscle cell proliferation	GO Biological Process Annotations 2025	1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
Ureteral obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_69_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Esophageal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Laryngeal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
BRD-K25330450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00776
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.912
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
BRD-K87158974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12368
GSE134896_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Idiopathic interstitial pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Neural ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
Triamcinolone_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0238781
BRD-K72146456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00491
PMC6026875-MOL2-12-1104-s002.xlsx-List_of_Cancer_Associated_Molec-Tet-MIST1_Cancer_Molecules_BHLHA15	Rummagene Transcription Factor Associations 2026	1.0	null
FEZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14924
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7034
GSE153124_4_v_3_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_3_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
PMC5578490-pgen.1006879.s020.xlsx-ETV1_ChiP_pks_tags_txt-Gene_Name_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45265701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38463
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09954
BRD-K93894185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16957
regulation of inflammatory response	GO Biological Process Annotations 2025	1.0	null
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
CDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37921
BRD-K08199068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11802
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92062
Lumbar spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
PMC9646482-mmc15.xlsx-ST15B_AA-specific-pQTLs-Unnamed_13_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161302,GSE161304_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Upstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1899
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5131
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_82_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17209411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62964
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
BRD-K37304120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30263
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
GSE252857_1_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96946
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.739
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4524
beta-catenin-TCF7L2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
BRD-K53396471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02214
Tongue epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
Urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
Synovitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
GSE218814_1_v_0_suv39h1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Myofibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.026
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82674931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7148
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-TPRX1_UP-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_up_to_an_FPKM_of_at_least_2_TPRX1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13181
Stratum intermedium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
BRD-K97224540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67447
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113106_0_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94629607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02312
BRD-K04939366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45892
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235682_3_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01371603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05269
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5517
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
BRD-K94881465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02816
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46609
hfff2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12749580-42003_2025_9274_MOESM5_ESM.xls-Supplementary_Data_2B-Supplementary_Table2B_Full_results_of_the_proteome-wide_MR_in_Ukb_ppp_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
PMC11257892-Table_1.xlsx-S2-Supplementary_Table_S2_All_results_of_the_preliminary_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.171
BRD-K23406211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43166
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0321
platelet-derived growth factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.793
BRD-K42650945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21913
Plasma membrane signaling receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.07
BRD-K14116382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54026
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68134791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00152
Human - Kidney - L3 - Mesangial	HuBMAP Azimuth Cell Type Annotations	1.0	null
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.082
PMC4470057-12943_2015_398_MOESM7_ESM.xls-probes_KD_inh_in_common-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2271
Vitiligo	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2699
ZNF738	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74262
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5798892-41421_2017_3_MOESM8_ESM.xlsx-down-regulated-Supplementary_Table_S3_Up-_and_downregulated_genes_in_ATF6-_-_hMSCs_compared_to_ATF6_hMSCs_late_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
KYSE-150 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
BRD-K58846294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01495
BRD-K33951208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91472
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5252
BRD-K52208857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16166
BRD-K98095706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09744
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
BRD-K11671824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91158
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Alveolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.627
BRD-K68149575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38276
BRD-K85633971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02624
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70499_0_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02453
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Oral squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
Tendon sheath	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of smooth muscle cell migration	GO Biological Process Annotations 2025	1.0	null
Fibro-adipogenic progenitor cell_Muscle_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Tongue cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12370121-pone.0329101.s003.pdf-1-IRF4_1_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34044309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58108
Integrin alphav-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.643
BRD-K09528868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84363
BRD-K20987582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02069
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_66_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173873_10_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dexamethasone_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0149877
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A68865339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38481
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.632
Lateral cuneiform bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44061011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56718
Myometrial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Esophageal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
BRD-K67835515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73962
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.232
Osteosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8502826__F10	PFOCR Pathway Figure Associations 2024	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4226688-oncotarget-05-8355.pdf-3-Table_1_Can_by_ARID3B_i_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.55
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81426
Cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.246
GSE127916_1_v_2_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
Synovium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ADF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
GSE209601_2_v_3_mef2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
Integrin alpha2-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87000197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36425
BRD-K73088636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26797
BRD-K06049932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20476
GSE96991,GSE97117_4_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A96536816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21424
chr8_133195720_A_G_b38	GTEx eQTL 2025	1.0	3.00585
BRD-K51363316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50088
Chondrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.138
Hca-F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mammary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40935524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43177
BRD-K46155894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13845
Trametinib_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0133195
GSE147626_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K89338336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7398
Laryngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
Osteophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.646
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.124
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04088
GSE194358,GSE194361_0_v_1_kdm5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.797
BRD-K83270526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.637
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91048
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3452
CRCGN008_HEPG2_24H:C11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04282
BRD-K12918607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74239
BRD-K16266179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35403
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81779733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.69931
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12549544-mmc2.xlsx-AA_D7_VS_D14-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
BRD-A42536341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32963
BRD-K60052521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33594
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
Activin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
Biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiofibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.729
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.006
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2054
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	82.9537
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151119_2_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74568352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41073
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5873
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.9663
PMC4858740-ncomms11473-s2.xls-HAdV-D9_cr1b_Library_1-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16935435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.11075
BRD-K24815102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47985
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_15_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_9_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7108
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Mesenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.895
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.37
Myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
GSE225869_1_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42953
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
col10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7621
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205556_1_v_0_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_10-Table_10_The_association_of_genetically_predicted_levels_of_proteins_with_the_risk_of_stroke_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of cell differentiation	GO Biological Process Annotations 2025	1.0	null
KYSE-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K65259629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.05399
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K99805333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00919
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95499061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4955
CRCGN008_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29443
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Medulloblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114258_3_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE162688_1_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52361779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42449
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
BRD-K20733942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07839
BRD-K12524715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15483
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14774
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
4T1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
BRD-K48276655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50415
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
PMC8185471-mmc7.xlsx-DEGs-SOX15_peaks-Day_6_SOX15-_-_upregulated_and_downregulated_genes_nearby_SOX15_CUT_Tag_top_10k_peaks_Related_to_Figure6_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.736
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3225
BRD-K52973286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06308
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.178
BRD-K88274759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97948
BRD-K79697020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30105
BRD-K63912037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66277
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.301
Thrombospondin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.367
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Alveolar epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.606
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Mesenchymal stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.277
Tendon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.3662
BRD-K42769174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05599
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7344
PMC11518751-Table1.xlsx-Table_S1_IV_for_MR-exposure_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83895653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83457
regulation of osteoblast differentiation	GO Biological Process Annotations 2025	1.0	null
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210225_0_v_1_uba6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.715
BRD-K55169051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14678
GSE111138,GSE111149_1_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12035825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04433
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0715
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.45708
GSE203308_14_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of cellular proliferation	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_84_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37601439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54389
Mammary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
Integrin alpha3-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.803
Pericyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.785
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18094884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04539
Uterine benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
BRD-K13461720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.6135
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29969800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31874
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Collagen network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Integrator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9941
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Preosteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.653
BRD-K28601178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42826
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Subcutaneous tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
Esophageal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.683
GSE252857_2_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
BRD-K05584347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.653
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
BRD-K16251850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86061
insulin-responsive compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.546
GSE196699_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13434
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.6549
Dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.725
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05557
Endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
BRD-A67254212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07419
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_51_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56802897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31767
Integrin alpha1-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_21_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Heart endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K39046749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43132
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16919185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19979
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S25-Table_S25_MR_resluts_of_blood_proteins_in_AGES_project_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63989441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20111
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.035
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Ivermectin_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0154076
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
Norrie disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
SMARCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01711
BRD-K13204142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06671
Blood protein levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66564
positive regulation of inflammatory response	GO Biological Process Annotations 2025	1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4812
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60689
BRD-K45190659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61593
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.30441
Muscle stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.576
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8451
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12702
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Epithelial stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
adipose-derived stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
Integrin alpha9-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_72_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic ductal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.471
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36323
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71337
BRD-K43798660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49618
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.65263
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6625
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_18_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder transitional cell papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
GSE179880_2_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8370976-41467_2021_24932_MOESM6_ESM.xlsx-Annotation-Supplementary_Data_4_GO_and_metascape_analysis_of_the_genes_downregulated_in_U87_cells_upon_ZNF768_knockdown_ZNF768	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36743230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14998
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.14658
BRD-K85554193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55635
BRD-K84241565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00452
Osteogenic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
BRD-K57468571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27527
Neointima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.176
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
BRD-K59028365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81197
Vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.684
BRD-K12884811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55982
PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_13-Table_13_MR_Steiger_analysis_to_infer_the_MR_causal_orientation_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101546_2_v_1_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Infigratinib_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0146388
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Infratentorial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
CRCGN016_MCF10A.TP53.M_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34218
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE252857_1_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-ATF3_TGAYRTCA_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Brain_CT2_DLIT 147	HuBMAP ASCT+B Annotations	1.0	null
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54335
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5736
Preadipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.369
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-Genes_with_ATF3_combined_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K90934902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35115
GSE203131_0_v_1_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.365
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K46313713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56261
BRD-K82401173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06876
BRD-K34703146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00988
Chondroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
GSE172490_5_v_1_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201401_2_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.8905
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
Laminin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.258
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Betamethasone dipropionate_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0345846
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.459
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
Epiphyseal growth plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43159427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38273
GSE127970_1_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.73
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.39119
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6395
GSE225869_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Extrinsic allergic alveolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.073
GRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95262
BRD-K89094496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04825
positive regulation of cell migration	GO Biological Process Annotations 2025	1.0	null
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20440082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27635
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
Esophageal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
Human - Kidney - L2 - Mesangial	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75065750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37875
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
Osteocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
GSE127970_2_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.891
GSE203308_8_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0873
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
BRD-K18313650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05658
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
Anterior chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of smooth muscle cell migration	GO Biological Process Annotations 2025	1.0	null
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_20_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.896
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_30_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.593
Periodontal ligament cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S26-Table_S26_MR_resluts_of_blood_proteins_in_AGES_project_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
laminin-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
Endometrial adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Endoplasmic reticulum-plasma membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.935
GSE98755,GSE98756_3_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26786741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18155
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chondroclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56868
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.797
GSE190555,GSE190557_2_v_3_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3952
Subcutaneous adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.867
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8718
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0042
Cholangiocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-ATF3_CBCTGACGTCANCS_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
External ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
GSE201668_0_v_1_ncor2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.888
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
Tooth germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
PMC8208823-mmc2.xlsx-CDX2-KO_mesenchymal_DEG-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12823428-43587_2025_1018_MOESM3_ESM.xlsx-ST12-Supplementary_Table_12_Main_mendelian_randomisation_results_of_plasma_proteins_on_delirium_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.365
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.386
interleukin-12 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.033
GSE225982_1_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain_CT2_DLIT 147	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
GSE116930,GSE116935_1_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
MG-63 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
BRD-K52406139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98158
NRK-52E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
BIC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
PMC3172216-pone.0023082.s005.xlsx-EGR1_expression_table_txt-CLID_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11079244-Data_Sheet_2.XLSX-Supplementary_Table_2-Supplementary_Table_2_Genetic_instruments_of_plasma_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K13488816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5401
BRD-K71566411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33952
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K04725393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00985
BRD-K35209334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22206
BRD-K54621976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06444
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.417
Laryngeal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08865
BRD-K69423881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37396
External encapsulating structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.683
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.694
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.009
Osteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.832
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.348
BRD-A96308662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16791
BRD-K91197462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36505
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Wsunhl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
PMC7798015__F4	PFOCR Pathway Figure Associations 2024	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Synovial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.374
Allantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
lm8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
BRD-K20110031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26977
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.63175
BRD-K59045095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65411
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
Preadipocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
PMC4686761-ncomms10068-s3.xlsx-S2G-MSC_down_specific-Supplementary_Data_2G_-_expression_of_down-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.101
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174406_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196699_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12692
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Betamethasone dipropionate_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.012965
Tenascin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.939
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7535
SOST-related sclerosing bone dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73878
CIRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18925
Graves' disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.146
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.225
BRD-K96493283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05025
Hyperostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
PMC5472759-ncomms15770-s2.xlsx-KIRC_mean_chr8_GISTIC_CN_by_gen-Supplementary_Data_1_TCGA_KIRC_mean_CN_near_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
Mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.147
GSE127205_1_v_0_asf1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.01
BRD-K24669989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70857
BRD-K50345393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05529
BRD-K73581966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08164
BRD-K35480932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18106
BRD-K94411351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0065
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
GTEx Uterus 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-3.76936
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Differentially_expressed_genes_DEGs_upon_CDC20_knockdown_under_37_culture_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S22-Table_S22_MR_resluts_of_blood_proteins_in_AGES_project_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
collagen-containing extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.004
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52026
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.336
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1142
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_39_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40260328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44993
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86111620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61684
Osteoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tendon sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.784
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.938
GSE210101,GSE210114_11_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K28656917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74411
SMAD protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
BRD-K36160951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3767
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.129
Squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.867
Microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.25
BRD-K53186055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10294
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186810,GSE186813_3_v_1_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
BRD-K39087188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68652
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
PMC12749580-42003_2025_9274_MOESM5_ESM.xls-Supplementary_Data_2A-Supplementary_Table2A_Full_results_of_the_proteome-wide_MR_in_deCODE_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91585756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08774
GSE151119_3_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.145
PMC11659389-42003_2024_7403_MOESM4_ESM.xlsx-4-Supplementary_Table_4_Result_of_the_primary_proteome-wide_MR_of_SCC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27893
GSE203308_1_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus pulposus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
GSE248858_6_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K00909602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31994
BRD-K16780806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20073
GSE184087_0_v_5_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dermal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50623282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00824
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_0_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7021759-41467_2020_14682_MOESM10_ESM.xlsx-downregulated_genes-Table_S7_Dowregulated_genes_in_SKNMM_and_U2OS_cells_with_MYCN_induction_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5776
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.177
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BAIAP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69412
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217115_3_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34579
Colon adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87419143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09049
BRD-K41026056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31398
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2243
GSE70499_4_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bronchial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22940496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93594
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04219533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87223
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.593
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.808
Uterine fibroid	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
Extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11459707-12890_2024_3289_MOESM1_ESM.xlsx-TableS3_MR_results-Supplementary_Table3_The_causal_effect_of_proteins_on_IPF_risk_from_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142994_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.081
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
vacuole-isolation membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.144
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04865
GSE239784_1_v_0_sat1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9646482-mmc7.xlsx-ST7B_MR-EA_P-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Chondrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.828
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42361
GSE119564_2_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K33420995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74576
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_45_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
BRD-K09777330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29089
GSE100102_4_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.082
Inner chondrogenic layer of perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
BRD-K06842972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38032
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
Focal adhesion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.658
BRD-K52175660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08083
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tibialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
Type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
positive regulation of response to external stimulus	GO Biological Process Annotations 2025	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11956947-media-4.xlsx-C_GSEA_gene_sets-ATF3_Q6_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35520972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93902
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of defense response	GO Biological Process Annotations 2025	1.0	null
White adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.841
PMC11659389-42003_2024_7403_MOESM4_ESM.xlsx-3-Supplementary_Table_3_Results_and_IV_SNPs_of_the_primary_proteome-wide_MR_of_BCC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
PMC11259242-str-55-2045-s001.xlsx-Table_S4-Table_S4_Full_results_for_all_proteins_tested_with_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74676765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83286
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Interstitial lung disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.015
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S24-Table_S24_MR_resluts_of_blood_proteins_in_AGES_project_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SPRYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11959
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K11518913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9069
Dental lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_81_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11565774-media-1.xlsx-ST19-Olink_CHIP-protein_MR-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_48_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72807299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40721
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sclerosteosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
BRD-K37029442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13494
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.25304
BRD-K94145457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48493
GSE68628_1_v_0_abcc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
BRD-K70875838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17695
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18285
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_4_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3686578-1471-2105-14-178.pdf-1-SOX9_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196699_7_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
Mammary epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.388
Integrin alpha6-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.104
Cobimetinib_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0130216
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.202
BRD-K97588749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55794
Fibrinogen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Temporomandibular joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4334
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04264
BRD-K89770910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9382
PMC10771430-42003_2023_5737_MOESM3_ESM.xlsx-S4-MR-AAM-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90366266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13075
Cancer	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2497
ZNF341	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70018
Myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
PMC11748740-41598_2025_85338_MOESM1_ESM.xlsx-Table_S2-Table_S2_The_cis-pQTLs_Pass_Instrumental_Variable_Selection_Test_for_Primary_MR_Analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MC-3T3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
BRD-K87595216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26947
BRD-K75529374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.853
BRD-K96284156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57341
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Familial adenomatous polyposis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
BRD-K57626519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.93596
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
BRD-K13049124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46862
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37235
Mandibular condyle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A89499670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60533
Clobetasol propionate_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0400433
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9106
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-THP-1_MLL-AF9_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
LX-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.996
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adipocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
BRD-K28927944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28247
BRD-A71962374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09826
Skin carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
BRD-K93811242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27285
Interferon regulatory factor 5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
BRD-K59232896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39721
Interstitial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
BRD-K81810589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48813
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210862
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-ATF3_TGACGTCA_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Preosteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8716
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39406901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02347
BRD-K63163033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91121
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3721
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
HaCa-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.457
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_12_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Odontoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
BRD-K04930806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60029
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8648
Mesenchymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
GSE206870,GSE206872_4_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.386
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96991,GSE97117_5_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
GSE172490_0_v_1_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Salivary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6731
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
Fat pad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.872
CRCGN008_HEPG2_24H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04705
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Larynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.865
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.637
BRD-K77445233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82167
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE124014_0_v_1_nnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Osteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.21
BRD-K25284184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5611
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9217
BRD-K79712504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12789
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.365
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4876
BRD-K41993678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66711
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37331547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.80139
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91406875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08094
PMC10319848-mmc1.pdf-3-FOXS1_FOXS1	Rummagene Transcription Factor Associations 2026	1.0	null
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65324
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.72095
PRSS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20176
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
BRD-K67177501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.8074
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4101
BRD-K81206010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10395
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51196703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43574
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8469
BRD-K45928581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.005
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83949633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0103
Human - Motor Cortex - Cross-Species Cluster - Layer 6 glutamatergic neuron, intratelencephalon-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
Oral cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1929
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Muscle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
PMC12532594-41380_2025_3119_MOESM1_ESM.pdf-216-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE244940_0_v_1_edf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36941
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K13960193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05377
Tibialis anterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
BRD-K93698227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13179
BRD-K73149920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03667
SCC-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
BRD-A57285050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19887
Betamethasone dipropionate_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0151588
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3395
Keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.168
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.244
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
BRD-K29260599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03388
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37659
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9575
BRD-K25595086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04499
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
chr8_133111831_C_T_b38	GTEx eQTL 2025	1.0	1.0092
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7107
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96991,GSE97117_3_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7242
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5673
Myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.076
BRD-K76628522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06058
BRD-A95970093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51265
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Activin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.196
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8804
BRD-K15607890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42884
BRD-K91500340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25851
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
BTBD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83057
Clobetasol propionate_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0126288
BRD-K38434557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36764
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
Meniscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.223
ZC3HAV1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3532
GSE87615_0_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1926
BRD-K22668106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18061
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
BRD-K64222382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3974
BRD-K84158675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13898
BRD-K48171978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06596
PanIN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.23988
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8348
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
BRD-K13697445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40006
BRD-K61522760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6554
Gastric cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.756
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9821
BRD-K38617061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63305
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8168
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K97943226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62964
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DTP3_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0218228
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.229
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
BRD-K71262871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28722
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.81
BRD-K23800773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37621
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1492
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65923
Leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.007
BRD-K49628278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16289
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
Integrin alphav-beta3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.052
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HME cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
GSE111035,GSE111040_8_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Integrin alphaM-beta2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
GSE196699_7_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.876
BRD-K01667746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34186
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	369.423
Breast invasive ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
Saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08958
BRD-K10435664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81336
Chondrosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
Rheumatoid arthritis disease specific fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-ATF2_UP_V1_DN-Ensemble_gene_ID_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
BRD-A20477000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40015
GSE70499_0_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82130737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00013
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
Red bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50726251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0369
BRD-K69396470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96836
GSE70499_3_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.365
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K63626200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41501
Cellular anatomical entity	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.229
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.365
GSE223241_2_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11699013-12672_2024_1699_MOESM1_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_The_association_between_proteins_and_CLL_in_the_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68968009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31152
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18296
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_3_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE100102_2_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2284
BRD-K66541472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09591
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234334,GSE234336_1_v_0_zhx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1356
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67014
Granulation tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.298
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.811
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_75_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
PMC11473359-44161_2024_545_MOESM2_ESM.xlsx-Table_16-Table_16_Information_of_genetic_instruments_used_for_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Cancellous bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.697
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90049800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17936
GSE142210_11_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE252958_1_v_0_znf469_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0126
BRD-K19411393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20307
BRD-K28268716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25312
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.865
PMC4686057-pone.0145107.s001.xlsx-PAA-CAA-Unnamed_0_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.865
Femur	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.326
GSE246195,GSE246305_1_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
BRD-K98451611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23888
GSE156033_1_v_2_sparc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chondrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.391
CSL-Notch-Mastermind transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
Pneumococcal bacteremia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
BRD-K16525290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04816
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.51792
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2708
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K21864149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18258
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cargo receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.185
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3784
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87010407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31821
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4901
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5879
GSE186810,GSE186813_3_v_1_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169697,GSE169725_0_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cementum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K61533770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3728
GCLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49046
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE246195,GSE246305_4_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8390472-41598_2021_96750_MOESM1_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68463857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.05203
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tunica media vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49694
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37622
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intervertebral disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
BRD-K51572611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37556
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
Enamel organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.41195
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.79228
Alveolar cell type II	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
Medication use (thyroid preparations)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20608
GSE239844_6_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2974
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.84
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.365
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2688
BRD-K77875023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3931
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Alveolar bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
p2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Stomach carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.989
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.974
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206870,GSE206872_4_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41311678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07839
BRD-K83603369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09151
BRD-K33044659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41712
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_4_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.076
Cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.229
HA22T/VGH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
Obstructive nephropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
beta-catenin-TCF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.77
BRD-K18768614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5728
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214596,GSE214598_1_v_4_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K50443235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0825
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25872
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.788
BRD-A73618687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42081
PMC12503973-3972293.f8.xlsx-Supplementary_table7-Supplementary_Table_8_MR-PRESSO_Results_in_the_Discovery_and_Replication_Phases_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51398207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08457
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77634326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81414
GSE211931_1_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Articular cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.899
PMC11659389-42003_2024_7403_MOESM4_ESM.xlsx-5-Supplementary_Table_5_Result_and_IV_SNPs_of_the_primary_proteome-wide_MR_of_MM_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
b16f0	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.524
Mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.354
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2343
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51585
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-MYOD1_MYOD1	Rummagene Transcription Factor Associations 2026	1.0	null
Vertebra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
PMC11042960-aging-16-205711-s002.pdf-186-CC2D1A_CC2D1A	Rummagene Transcription Factor Associations 2026	1.0	null
Dental pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
BRD-K07756997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86123
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Satellite cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.486
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.229
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.6788
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CDC14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12846
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99944747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71372
PMC8481886-Table_1.xlsx-A_subsets-bone_marrow_MSC_adipose_tissue_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null