association	dataset	threshold value	standardized value
Colorectal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.598
Regulatory T (Treg) cell_Peripheral blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36677
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.261
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.2508
cell part	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAVER1	DepMap CRISPR Gene Dependency	1.0	2.00291
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230656
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63234
TUHR-14TKB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.434
chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.511112
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
Immunoglobuin Deficiency	DisGeNET Gene-Disease Associations	1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	1.0	7.18814
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01372
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39013
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21949
Status Epilepticus	DisGeNET Gene-Disease Associations	1.0	null
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5405
mantle zone of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50085
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cross	GeneRIF Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5045
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6996-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09319
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35325
Castleman disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
Bronchial mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
Prostate adenocarcinoma_PRAD_TCGA-G9-7521-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7SK snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.582
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC8327843__F2	PFOCR Pathway Figure Associations 2024	1.0	null
MOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22298
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6446
7d4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
RBFOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79902
Acquired immunodeficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
BRD-K31889353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78774
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6995
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.11099
teleost	GeneRIF Biological Term Annotations	1.0	null
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
Gut mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
Skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3694
regions	GeneRIF Biological Term Annotations	1.0	null
G alpha (i) signalling events	Reactome Pathways 2024	1.0	null
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6874977__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
PIAS1_Depletion_GDS5076_12_human_MDA-MB 231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K15226746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1122
ELL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40135
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.258
interleukin-5 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35591
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
duplication	GeneRIF Biological Term Annotations	1.0	null
IGF1_OE_GDS3484_542_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.54
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22744
Lung squamous cell carcinoma_LUSC_TCGA-85-6561-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.979
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5941-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.196
Glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00752
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-513a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Thymic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
Respiratory allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.972
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5093
novobiocin-576	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
muscle	GeneRIF Biological Term Annotations	1.0	null
UCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92284
Ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.989
Oral squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
BRD-K36848506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00629
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45380779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56173
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.60225
GSE180951_2_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13005
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.105
BRD-K29331543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30898
glial cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.29623
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased susceptibility to experimental autoimmune encephalomyelitis	MPO Gene-Phenotype Associations	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
TENT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13383
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56726
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12518
Replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.447
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6462
PMC4029819-pone.0098069.s006.xlsx-Sheet1-Table_S5_FSS_analysis_of_FOXA1_high_versus_FOXA1_low_cases_in_metastases_p-value_0_01_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54622
GSE182680,GSE182683_5_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03132
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25155
Lewis lung carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.619255
Perturb_17348_KO_Rora_SRP298165	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.44627
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2039
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
antiapoptotic	GeneRIF Biological Term Annotations	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.965
GAPDHS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46245
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46377
BRD-K76423693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10729
etidronic acid-4387	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2339
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36633
p2 part of the zona limitans core population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35269
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
sno(s)RNA-containing ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.871
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
PMC4259415-oncotarget-05-10198-s002.xlsx-Sheet1-STAT3_Pathway_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.479
receptor activity	GO Molecular Function Annotations 2015	1.0	null
there	GeneRIF Biological Term Annotations	1.0	null
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12522
environmental	GeneRIF Biological Term Annotations	1.0	null
proliferation	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7319
vMIP-II	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
THOC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00538
RUNX1	ChEA Transcription Factor Targets	1.0	null
kidney cortex necrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.852811
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31830316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14168
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86597
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21258
dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.131129
umbilical vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193781
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29155
Lymphoid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
liminal part of r4 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13808
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6419
16135788-Table24	GeneSigDB Published Gene Signatures	1.0	null
calcium-mediated signaling	GO Biological Process Annotations 2025	1.0	null
sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.185612
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K83670600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27043
BRD-K60057192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25614
Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-875 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
PBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30541
Bronchoalveolar lavage fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.588
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79979
RT11284	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40562
BRD-K07497357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0078
BRD-K95951626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07384
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.164
Bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
gk1.5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.517
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.37455
Lung squamous cell carcinoma_LUSC_TCGA-22-1000-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4863
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950885
Meningioma	HuGE Navigator Gene-Phenotype Associations	1.0	null
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30306
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10626
large granular lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263669
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70251
RND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02787
SCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93853
p1Lim part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10745
membrane	GO Cellular Component Annotations 2015	1.0	null
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06559
Lung squamous cell carcinoma_LUSC_TCGA-60-2721-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.8461
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7976
Hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.381
BRD-K04147413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42342
BRD-K85284710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02728
Prostate carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.408666
CTNNB1_Inactivation_GDS2984_628_mouse_Intestinal crypts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
distinct	GeneRIF Biological Term Annotations	1.0	null
BRD-K29685390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00362
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27188
Thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56498
BRD-K16826857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17155
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
kaposi's sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.961634
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63027
Lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.851
BRD-A27693633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47794
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6858
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
talk	GeneRIF Biological Term Annotations	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36196
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29946
kasugamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01335
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14261
BRD-K13888422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00223
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79318959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0404
BRD-K50604515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12147
CRCGN008_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19235
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73625
blood	GTEx Tissue Gene Expression Profiles	1.0	1.7957
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60190533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93217
GATA1	ENCODE Transcription Factor Targets	1.0	null
enhances	GeneRIF Biological Term Annotations	1.0	null
CCL1	Pathway Commons Protein-Protein Interactions	1.0	null
Skin-t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0827617
BRD-K24156533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40476
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hfff2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3321
BRD-K46549154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64622
basophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.520041
Vitiligo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.004
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0682
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35355
Chronic Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
w chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.708366
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64899
BRD-K56161792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71206
Cell septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.328
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ERG_01_17	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.633
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.27687
nicotine_myzus persicae_gpl9470_gse18658	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93212
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88869
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.574994
hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.122788
Perturb_6214_KO_Hdac_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.95716
Thorax	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.816
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34942
Diphtheria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.18779
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3173-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
TALL1	CCLE Cell Line Gene Expression Profiles	1.0	3.40814
BRD-K60661821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01311
migration	GeneRIF Biological Term Annotations	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.483604
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ZNF600	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50583
T-cell non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.806
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.40243
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
Acquired Immunodeficiency Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCIH2029	CCLE Cell Line Gene CNV Profiles	1.0	1.44873
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
arachidonic acid-441	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862956
Tongue-immune cell	Tabula Sapiens Gene-Cell Associations	1.0	1.55505
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_01_18	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60742
Thymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40715
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19405
BRD-K78972225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12153
Th17 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.824
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19A-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE211177,GSE211178_4_v_10_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6175-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Liver sinusoidal endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
DnaB helicase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.269
NCIH1666	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83169
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.56521
Clear cell renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
SLC16A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66662
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45229
ACSL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56063
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07855
Status Epilepticus	CTD Gene-Disease Associations	1.0	2.88009
Lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22597
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849291
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05281
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.02845
CRCGN015_MCF10A.TP53.M_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0081
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
mp6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory Tract Diseases	CTD Gene-Disease Associations	1.0	1.06844
T cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Interferon regulatory factor 5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CHDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68716
GSE129772_2_v_1_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL1_KO_GSE43695_681_mouse_lung, bleomycin treated	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSK3B_knockdown_206_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.74251
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5788
Aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
hypersensitivity reaction type i disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.575383
Alopecia areata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.992508
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6281
Status Epilepticus, Subclinical	DisGeNET Gene-Disease Associations	1.0	null
GRK6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_17031_KD_Nr3c1_SRP149816	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10345
coreceptor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-A54389315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20798
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57712
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.617
Specific granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
terconazole-4407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
skinspecific	GeneRIF Biological Term Annotations	1.0	null
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07689
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056846
Adrenal cortex disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
Collagen beaded filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
GATA1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167059
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1569
SW1783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.25676
Heart Failure, Right-Sided	DisGeNET Gene-Disease Associations	1.0	null
BRD-K16436767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39404
Dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.552
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6373
MYC_Activation - 21 days_GDS2025_727_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE211177,GSE211178_4_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8161-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF569	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59402
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ST3GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72185
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7578
BRD-K68683482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41345
adult t-cell leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.271886
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	1.6196
chemokine-mediated signaling pathway	GO Biological Process Annotations 2015	1.0	null
OVCAR-8	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76738
BRD-A19912945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02044
abnormal behavior	IMPC Knockout Mouse Phenotypes	1.0	null
bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.22865
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30859
interleukin-12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.268
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63566
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44561
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.50108
RCOR1	ENCODE Transcription Factor Targets	1.0	null
trunk	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of cytosolic calcium ion concentration	GO Biological Process Annotations 2015	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
GSE139239_3_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
use	GeneRIF Biological Term Annotations	1.0	null
obstructive	GeneRIF Biological Term Annotations	1.0	null
PMC6106745__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09022
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21493
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A819-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
PMC12041462-41598_2025_96542_MOESM1_ESM.pdf-4-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53519
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.918
Immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.274
Lung adenocarcinoma_LUAD_TCGA-55-6978-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
erastin-6412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10559
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
Sclerosing cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
Pulmonary eosinophilia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7393
CCL1	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.70498
Sputum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
MIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88608
systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.292616
multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.544318
hsa-miR-205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Oropharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
PIAS1_KD_GSE44024_133_human_breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.26913
Memory Disorders	CTD Gene-Disease Associations	1.0	1.04051
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75641
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.75
evolved	GeneRIF Biological Term Annotations	1.0	null
Integrin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.095
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
Platelet dense tubular network membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.984
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
Chancroid	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
SARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58551
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
CRCGN009_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18599
VMIP-II	DGIdb Drug Targets 2026	1.0	1.51234
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7691
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IV-01A-22R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510206
BRD-K36031198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10544
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.008
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.485289
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01768
T-cell acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28443
LNZ308	Achilles Cell Line Gene Essentiality Profiles	1.0	1.4734
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39972
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45532
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.156
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.619442
GSE129772_2_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular calcium ion homeostasis	GO Biological Process Annotations 2015	1.0	null
BRD-K20652606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29814
vMIP-I	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Chemokine receptor family	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MTREC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.173
B16-F10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
[Ni-Fe] hydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXM1_01_77	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59259
MAGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63785
BRD-K31462164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17654
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01787
BATF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.01568
EW22	DepMap CRISPR Gene Dependency	1.0	2.37119
BRD-K98061177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01568
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08861
hsa-miR-4289	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MAFK_02_183	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185399
homeostatic process	GO Biological Process Annotations 2015	1.0	null
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pneumocystosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.431519
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116367
Viral carcinogenesis	KEGG Pathways 2026	1.0	null
nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.561781
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03843
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1992
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.824013
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC37A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37905
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8624
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Chronic lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40446
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06019
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81853
BRD-K45986774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59045
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
BRD-K15898103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03374
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94333
biological_process	GO Biological Process Annotations 2015	1.0	null
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414293
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60705
pathways	GeneRIF Biological Term Annotations	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB3A_KO_GDS2482_705_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K38209615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27544
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IgG immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.071
BRD-K72224143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13313
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alpha-beta T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.454
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44223
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5464-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.836
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.897
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34827
glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061769
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.639
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41127
intermediate stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39479
JURKAT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peripheral T-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74624
BRD-K11804865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47732
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
furazolidone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27887
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2792
GDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66694
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.067558
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01223
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82694
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50207
basophils	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73230533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16993
Liver reticuloendothelial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53666
genomic	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7433-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chemokine receptor activity	GO Molecular Function Annotations 2025	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33139
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09615
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30722
brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24804
SACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94904
Gastric adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62805
Lymph_Node-regulatory t cell	Tabula Sapiens Gene-Cell Associations	1.0	1.32854
MHHES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58517
DNA recombinase mediator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.3
BRD-K99581286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24786
Lymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.825
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7736
blind uterus	MGI Mouse Phenotype Associations 2023	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.023
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60007
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1031
GSE217363_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bronchial epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121046
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
Tumor regulatory T cell_Peripheral blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
Fc-epsilon receptor I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.566
Birth Weight	HuGE Navigator Gene-Phenotype Associations	1.0	null
Adrenocortical carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.05247
TPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19783
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43056
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3024
BRD-K55044152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02123
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
Helper T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.471
primary effusion lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366007
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43935
GFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94978
BRD-K56916066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38739
dihydroergotamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29592
esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.096869
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thymus lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.683511
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02603
system	GeneRIF Biological Term Annotations	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
Suppressive regulatory T cell_Liver_Human	CellMarker Gene-Cell Type Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammatory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.953
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9375	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.19964
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
Rectum adenocarcinoma_READ_TCGA-EI-6917-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
alopecia areata	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.189859
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01513
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466111
BRD-K84761515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16244
BRD-K73006286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49573
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56124
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.960648
Cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
FUCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06291
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7357
Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.24684
pro-b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167823
CRCGN012_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79592
BRD-K91620436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01405
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.127
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22468
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04108
taxis	GO Biological Process Annotations 2015	1.0	null
NCIH1436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53893
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	1.10356
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
M1 melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
BRD-K10580455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38096
CRCGN017_MCF10A.TP53.M_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44005
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.261
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peripheral t-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.427765
peripheral	GeneRIF Biological Term Annotations	1.0	null
Side of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23586
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3055
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37854
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.001
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MZ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46097
decreased thigmotaxis	IMPC Knockout Mouse Phenotypes	1.0	null
Natural killer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obliterative	GeneRIF Biological Term Annotations	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.605
PDZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19298
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256568
Small nuclear ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.422
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.445805
Kaposi sarcoma-associated herpesvirus infection	KEGG Pathways 2026	1.0	null
Telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.934
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25092
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8933
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	0.983061
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58122
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Regulatory T(Treg) cell_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K44807762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03871
Reticuloendothelial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
pre-b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186843
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03785
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8537
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217974
GSE100316_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38179
BRD-K27139040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3539
LIVF001-011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72628
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8603
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7104-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50641
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.964
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Complement component C1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
Lung adenocarcinoma_LUAD_TCGA-55-6979-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28937085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83485
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
SW756	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75027
molluscum contagiosum	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.1605
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052988
allergic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.682294
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.950947
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08894
ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC8638098__F5	PFOCR Pathway Figure Associations 2024	1.0	null
MOLT16	CCLE Cell Line Gene Expression Profiles	1.0	1.90722
Nmyc_OE_GDS2406_14_mouse_LUNG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Thymus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.178
intermediate stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10497
Prostate adenocarcinoma_PRAD_TCGA-EJ-5509-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hair follicle epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
KRAS.50_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
primarily	GeneRIF Biological Term Annotations	1.0	null
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
pre-b-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.472704
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5460-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL11A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Divisome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.444
interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061964
hsa-miR-500a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89325
KIAA2026	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89814
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4057
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ligand	GeneRIF Biological Term Annotations	1.0	null
BRD-K13674694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30247
GSE112202_5_v_2_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.646519
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8443
GSE158438_4_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.86
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966533
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52265
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.26
Endocervical carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
decreased susceptibility to autoimmune disorder	MPO Gene-Phenotype Associations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28053
glioblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077284
erythroid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166654
BRD-K82815491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1528
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87973
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
innate	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7386-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22105
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2896
BRD-K42899345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08119
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.3554
BRD-K80972048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32658
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.5588
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.176587
phlebitis	GeneRIF Biological Term Annotations	1.0	null
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66186
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042252
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24286
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4437
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.47702
SPRING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79308
delavirdine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11528
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967413
atopic	GeneRIF Biological Term Annotations	1.0	null
BRD-K96745500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55771
okt8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
b-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.195501
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04732
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7351
CNOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06211
BRD-K99953989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49101
Dyskeratosis congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
those	GeneRIF Biological Term Annotations	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.482038
Anaplastic large cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
Lymphatic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.79
MTA3	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
flumetasone-3610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21403
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.768
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068628
Anaplastic thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.23
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0986
Lymphatic endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.856
vessel	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33013
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07132
SMC3	ENCODE Transcription Factor Targets	1.0	null
RNASE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26347
Allergic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.883
OVCA420	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
chemokine receptor activity	GO Molecular Function Annotations 2015	1.0	null
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
Anaerobic ribonucleoside-triphosphate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
Peptide GPCRs(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42312
CRCGN013_HEPG2_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20333
STAT3	ChEA Transcription Factor Targets	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51189
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42866
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08991
BRD-A41208012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64802
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.358
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integrin alphaL-beta2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08463
pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.083501
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
eosinophilic esophagitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.336876
Rectum adenocarcinoma_READ_TCGA-AG-4022-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocervical adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301758
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV-7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20238
recruitment	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3121-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
BRD-K42150052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48495
Ku70:Ku80 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214954
XRCC2-RAD51D complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.11503
CPNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50773
GATA1_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29229
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
population	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6989-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	2.14345
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4559
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02157
Lung adenocarcinoma_LUAD_TCGA-05-4417-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67041
BRD-K40001470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1766
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.558285
Regulatory T (Treg) cell_Liver_Human	CellMarker Gene-Cell Type Associations	1.0	null
Leukemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOLEDO	CCLE Cell Line Gene Expression Profiles	-1.0	-2.56773
pulmonary sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.198709
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4502
CAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51978
ATP13A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06659
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43001
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Simple Partial Status Epilepticus	DisGeNET Gene-Phenotype Associations	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.787
TUHR4TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33747
Integrin alpha6-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.702
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
17174972-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
cellular cation homeostasis	GO Biological Process Annotations 2015	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.678617
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12016
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20416
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12757
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Replication fork protection complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.148
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1701
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
CYP2D6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38298
SLC35B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3541
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54798
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0307
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chromosome, telomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.044
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.241
Buffy coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
recruited	GeneRIF Biological Term Annotations	1.0	null
appendix	HPA Tissue Gene Expression Profiles	1.0	1.03944
BRD-K93993903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79113
Interstitial lung disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00009
Regulatory dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.40008
SKMM2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.30773
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.398357
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.546
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
Peritoneal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
Extrachromosomal rDNA circle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
pramocaine-3811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Interferon regulatory factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.402
BRD-K59389251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1831
Granuloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
interleukin-27 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.914
Encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93901
SW403	DepMap CRISPR Gene Dependency	1.0	2.21773
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32183
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.06133
t-cell leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.194865
small	GeneRIF Biological Term Annotations	1.0	null
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84878
BRD-K12555854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34387
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.54729
BRD-K03840522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2911
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.99048
ABL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20406
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.18345
Peptide ligand-binding receptors	Reactome Pathways 2024	1.0	null
BRD-K55330917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62646
Inflammation	CTD Gene-Disease Associations	1.0	1.73758
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.63425
Encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.898
astrocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071139
BRD-K66327237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49514
Skin epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10976
BRD-K23670243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3473
C8orf33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53003
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4997
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.232836
MCTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49044
Bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.773
umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12854
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.819912
CALU1	CCLE Cell Line Gene CNV Profiles	1.0	1.64541
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45471
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56273
Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44121
Car cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
igg immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.247854
Ghost	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5868
BRD-A47166394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05999
astroglial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068173
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50634
HIBADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83565
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.598351
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874893
newly	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HQ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vasculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
locomotion	GO Biological Process Annotations 2015	1.0	null
BRD-K50443235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37032
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.106
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00009
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.053
CCL16	Pathway Commons Protein-Protein Interactions	1.0	null
Thymic medullary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
ligands	GeneRIF Biological Term Annotations	1.0	null
anuria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.371107
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42686
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057662
individuals	GeneRIF Biological Term Annotations	1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28002
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.10364
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78105
Pneumonitis	DisGeNET Gene-Disease Associations	1.0	null
DYNLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5643
BRD-K42804674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35305
adrenal cortex cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239007
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4568
Venule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
heterotrimeric g-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.513677
16513838-TableS2	GeneSigDB Published Gene Signatures	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03102
budesonide-2866	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19189
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70566
allergic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.541992
memory	GeneRIF Biological Term Annotations	1.0	null
Regulatory T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.657
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4327
surrounding	GeneRIF Biological Term Annotations	1.0	null
Bolting stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
L363	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.43889
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6825-01A-21R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2464
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908727
cterminal	GeneRIF Biological Term Annotations	1.0	null
lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169091
Perturb_17047_KD_IRF4_SRP201887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K61533770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04003
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00204
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
culture supernatant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266413
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9274
CAMA1	CCLE Cell Line Gene Expression Profiles	1.0	1.66086
adrenal gland	HPA Tissue Gene Expression Profiles	-1.0	-1.1132
T-lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
cellular homeostasis	GO Biological Process Annotations 2015	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2769
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85802892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3587
BRD-K43025624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19427
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57447
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.07444
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06849
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058433
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
adaptive	GeneRIF Biological Term Annotations	1.0	null
ATN-1	GDSC Cell Line Gene Expression Profiles	1.0	3.50595
GATA1	ChEA Transcription Factor Targets	1.0	null
BRD-K74665927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22853
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06004
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.046
graft-versus-host disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.889
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
vMCC-I	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77418
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
BRD-A04975445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87163
Adenoid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR120_KO_GDS4830_414_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.898
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2808
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Division septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
BRD-K26237438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1969
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02994
Hypertension	CTD Gene-Disease Associations	1.0	1.1529
Inflammation	DisGeNET Gene-Phenotype Associations	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16078
lung	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6205-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interleukin-12 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
NKX2-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14555
496100285_TCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32468
BRD-K73357447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31948
Perturb_17145_OE_Xbp1_ERP110244	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49941
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
nervous	GeneRIF Biological Term Annotations	1.0	null
allergic bronchopulmonary aspergillosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.198386
exclusively	GeneRIF Biological Term Annotations	1.0	null
mast	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chemokine signaling	WikiPathways Pathways 2024	1.0	null
CHPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89436
cytokine receptor activity	GO Molecular Function Annotations 2015	1.0	null
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
Tonsil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.422
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.60776
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
c-c chemokine receptor activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_3367_KO_H1_SRP234772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.594
CREB_DEPLETION_GDS3487_41_human_K562 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
UBB_KO_GDS3906_492_mouse_Testis -  14 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96981233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13645
BRD-K55288106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04769
CSF1-CSF1R complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
PMC12036091-jcav16p2321s1.pdf-27-OVOL1_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
asthmatic	GeneRIF Biological Term Annotations	1.0	null
inflammation	GeneRIF Biological Term Annotations	1.0	null
Thyroid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
Myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphangioleiomyomatosis disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
CAMKK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32594
BRD-K40189164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76035
TBP	ENCODE Transcription Factor Targets	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
DNA repair complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.865
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60579
DIFI	DepMap CRISPR Gene Dependency	1.0	4.75644
SNUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64998
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.35644
IgE B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
p3 part of the ZL core	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86038
BRD-K46639367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20929
Bile duct cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.654
ccl1	GeneRIF Biological Term Annotations	1.0	null
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
NCI-H2085	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90213
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15616
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46821
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0385
Learning Disorders	CTD Gene-Disease Associations	1.0	1.26794
single-organism process	GO Biological Process Annotations 2015	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35325
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9396
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2551
Lung adenocarcinoma_LUAD_TCGA-86-8280-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.654
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Germinal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.658
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08722369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13169
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_3_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10801
PMC3979852__F8	PFOCR Pathway Figure Associations 2024	1.0	null
Smooth endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
pre-t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.603697
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.948
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36401
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45875
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.161
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9723
eosinophilia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.596792
Peanut allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.24
interleukin-23 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.089
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.80429
GSE146425,GSE146428_1_v_0_lef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22449045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30517
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
pollutant	GeneRIF Biological Term Annotations	1.0	null
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.092908
Perturb_6215_KO_Hdac1_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.74424
macrophages	GeneRIF Biological Term Annotations	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7305
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.996
Legume allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
BE-13	GDSC Cell Line Gene Expression Profiles	1.0	2.41309
spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.975015
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
decreased anxiety-related response	MGI Mouse Phenotype Associations 2023	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3112
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.757
Lung adenocarcinoma_LUAD_TCGA-93-7347-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REDD1_Repression_GDS3558_73_human_Blood Myeloid Cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.754
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30511
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394953
dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.962039
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.155
hbe cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307528
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891157
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.302912
CHAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96183
BRD-K04429417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09303
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18482
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42591
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_38_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51855
RPMI8402	CCLE Cell Line Gene Expression Profiles	1.0	1.79973
chemokine binding	GO Molecular Function Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Raji	GDSC Cell Line Gene Expression Profiles	1.0	1.44418
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22533
BRD-K47762331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56309
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
superficial gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2152
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29002
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99503
Thymus gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04882
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04696
TRPS1_Mutation_GDS4493_594_mouse_Whisker pads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
icSARA deltaORF6_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.35976
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.75
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39019
BRD-K93023309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3071
BRD-K47087435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02182
bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275444
Parenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
diffuse large b-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.421016
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0567
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55007
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
present	GeneRIF Biological Term Annotations	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03755
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3061
Thymus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25554
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953541
cellular ion homeostasis	GO Biological Process Annotations 2015	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
immune response	GO Biological Process Annotations 2015	1.0	null
16536878-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCL18 signaling	WikiPathways Pathways 2024	1.0	null
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99115
optic fiber layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09489
Lung adenocarcinoma_LUAD_TCGA-05-4389-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.919
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36737
Gemin3-Gemin4-Gemin5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.735
BRD-K15867859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06882
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05284
Tumor-infiltrating regulatory T cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6115
chemokine receptor activity	GO Molecular Function Annotations 2023	1.0	null
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.38
ADNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46339
GDF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28767
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03843
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
PMC11867963-Table1.xlsx-Sheet1-CEBPA-DT_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
produced	GeneRIF Biological Term Annotations	1.0	null
B16-F1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47065
Necrosis	CTD Gene-Disease Associations	1.0	1.08797
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FEV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11824
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
BRD-K47254434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71566
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
Primary effusion lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65462
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.641433
SCLY	ChEA Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
wall	GeneRIF Biological Term Annotations	1.0	null
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390044
Hybridoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.665
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW48	DepMap CRISPR Gene Dependency	1.0	2.0232
membrane part	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-616	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
cytosolic calcium ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Cytotoxic T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.118
BRD-K92398088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13029
BRD-K78747341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76099
subset	GeneRIF Biological Term Annotations	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.017
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57371
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6515-01A-21R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
driven	GeneRIF Biological Term Annotations	1.0	null
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08899
GSE205291,GSE205292_1_v_3_drd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168587,GSE168752_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186810,GSE186813_3_v_1_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48778
Perturb_17045_KD_BATF3_SRP230607	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.6274
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04577
EFNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2899
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6181
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36273
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7395-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
Glioblastoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
GPCR ligand binding	Reactome Pathways 2024	1.0	null
k1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
interleukin-35 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.271
U5 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.747
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14279
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04342
Lung adenocarcinoma_LUAD_TCGA-49-6744-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75815721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28155
BRD-K14090520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25948
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.191777
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28919
phentolamine-2323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83956
cellular process	GO Biological Process Annotations 2015	1.0	null
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68909
BRD-K41412255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5465
Decidua basalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SP-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89788
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRAF_drug inhibition_GSE42872_368_human_A375	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7918-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
virion part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.260931
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06962
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
HCC1569	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6546
Ribonuclease MRP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
ZNF454	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
Cytokine-cytokine receptor interaction	KEGG Pathways 2026	1.0	null
CCL8	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83479
effector	GeneRIF Biological Term Annotations	1.0	null
bronchial epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115526
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.01025
Lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.851
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.97
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95521279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04187
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28695
b-lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301398
BRD-K75999096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10989
DIDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77842
CRCGN017_MCF10A.TP53.M_24H:P11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56072
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44748
Perturb_9773_KO_Tkt_SRP313974	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.16258
T-cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55428
umbilical vein endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281423
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MN-01A-22R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
PMC7100912-EMS85677-supplement-Suppl__Tables_1_8.xlsx-Table_6-Supplementary_Table_6_Nanostring_gene_expression_profiling_of_memory_T_cells_transduced_with_BHLHE40_BHLHE40	Rummagene Transcription Factor Associations 2026	1.0	null
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	1.70493
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.923
TZM-bl cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
Perturb_3341_OE_miR27_SRP092617	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.60201
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.241
NPRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1109
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.119
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
BRD-K78828094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21313
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35464
Lymphotoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.417337
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43182
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.158882
Sarcoma_SARC_TCGA-DX-A1L1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rescue	GeneRIF Biological Term Annotations	1.0	null
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1782
Thymus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69898
Perturb_11723_KO_Eomes_SRP187979	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.385143
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4861-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4LX-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
psi2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
thymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.606916
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.87338
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32497
PMC4823983__F5	PFOCR Pathway Figure Associations 2024	1.0	null
na cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.536625
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21493
molecular_function	GO Molecular Function Annotations 2015	1.0	null
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74984
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06015
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17344
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I1-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15947096-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
huvec cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281423
Shelterin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.879
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56139
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Molluscum contagiosum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.27489
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chromophobe renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08034
SFRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56492
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0726
MYC	ENCODE Transcription Factor Targets	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytokine receptor activity	GO Molecular Function Annotations 2025	1.0	null
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
CRCGN013_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03201
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
decreased anxiety-related response	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K08939947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02535
BRD-K41044903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41559
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
enriched	GeneRIF Biological Term Annotations	1.0	null
clozapine-6188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6438
t-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.503141
ZK 756326	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08829
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.881
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19022
decreased locomotor activity	MGI Mouse Phenotype Associations 2023	1.0	null
Primary Sjögren'S Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0437
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93293
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EM-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7761-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
appendices_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.916145
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21481
Integrin alphav-beta8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
BRD-K11705648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52049
BRD-K78363521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70133
abnormal self tolerance	MPO Gene-Phenotype Associations	1.0	null
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
BRD-K26526202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46829
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01934
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
CLDN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93902
Infralimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24661
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-467-TGIF1_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95716
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.81274
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.261
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489447
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0872
MTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39876
valproic acid-4438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53050301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01274
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07431
IgG4-related disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
interleukin-2 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28355
viral	GeneRIF Biological Term Annotations	1.0	null
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510599
ARMCX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0186
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40769
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04477
Tcof1_KD_GDS998_155_mouse_neuroblastoma N1E-115 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
UMUC7	DepMap CRISPR Gene Dependency	1.0	3.4181
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.726
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8348198__F3a	PFOCR Pathway Figure Associations 2024	1.0	null
SLR24	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.24853
BRD-K95901503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22124
BRD-K34688736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0424
BRD-K21990111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05608
PGM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84771
STARD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63437
extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.415728
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.879
PMC7495487-41598_2020_71030_MOESM2_ESM.xlsx-Sheet1-NR1A1_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Cajal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.212
Splenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2167
EBF1	ENCODE Transcription Factor Targets	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.362273
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.57
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7326
lymphocytic	GeneRIF Biological Term Annotations	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
NCIH28	CCLE Cell Line Gene CNV Profiles	1.0	1.60524
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.241196
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Asthma	DisGeNET Gene-Disease Associations	1.0	null
RAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891157
squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067514
BRD-K16570418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95314
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28753
BRD-K22564762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89194
Leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.843
BRD-K83836941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00705
expanded	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4161-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.809
Inflammation mediated by chemokine and cytokine signaling pathway	PANTHER Pathways	1.0	null
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53773
BRD-K48875630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42989
Naive T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.249
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11888
TGF-beta_OE_GDS2974_137_mouse_corneas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Integrin alphav-beta5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28195874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3744
mature t-cell and nk-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.34384
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Allergic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08271
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2014	1.0	null
BRD-K42575648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82514
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.114
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.75199
BRD-K42828928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34899
EIF4EBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82517
pre-T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.804
SPARC_Deficiency_GDS3636_524_mouse_Lens epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TLX1_01_246	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.71033
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.593
eosinophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29489
CRCGN011_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01095
release	GeneRIF Biological Term Annotations	1.0	null
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-T_F1-pT3_FU1_shared_Treg_ZNF135	Rummagene Transcription Factor Associations 2026	1.0	null
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070059
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.761
HS739T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62932
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.94537
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01725
Lung adenocarcinoma_LUAD_TCGA-44-A47A-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.1132
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	1.2768
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6534
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7376-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.252
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.974478
CHST7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98877
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
Oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL1-CLOSEST_GENE_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27729
PMC12559107-12035_2025_5221_MOESM1_ESM.xlsx-Supplment_Tab_3-Supplement_Tab_3_The_result_of_MR_analysis_for_SCZ_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GOLM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63961
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
gamma-delta T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.54
Nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.972711
Kaposi's sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
g-protein coupled chemoattractant receptor activity	GO Molecular Function Annotations 2015	1.0	null
GSE186810,GSE186813_3_v_1_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
respiratory epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102653
Lung squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
Leukemia, Myeloid, Acute	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K47724892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0075
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81237
Hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
METTL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52162
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33167
RPMI8226	DepMap CRISPR Gene Dependency	1.0	5.30703
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08125
conditions	GeneRIF Biological Term Annotations	1.0	null
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19843
KLF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21444
Monomeric IgA immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73208
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
C-C chemokine binding	GO Molecular Function Annotations 2025	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.7369
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.874
hsa-miR-4755-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6533
induction	GeneRIF Biological Term Annotations	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989542
GLYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46262
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
T helper2 (Th2) cell_Undefined_Human	CellMarker Gene-Cell Type Associations	1.0	null
HEXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26687
TMED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6597
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35146
ccl18	GeneRIF Biological Term Annotations	1.0	null
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35456
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156342
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
thymus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22685
16140871-SuppTable7	GeneSigDB Published Gene Signatures	1.0	null
decreased susceptibility to experimental autoimmune encephalomyelitis	MGI Mouse Phenotype Associations 2023	1.0	null
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3746
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6638
Daytime sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
DHRS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60279
NCIH1385	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44516
tetraspanin-enriched microdomain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.709
[<sup>125</sup>I]CCL1 (mouse)	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
SARS-CoV MA15_Day4_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.48431
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
BEN	CCLE Cell Line Gene Expression Profiles	1.0	1.36356
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ac2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
lymphocytes	GeneRIF Biological Term Annotations	1.0	null
BRD-K40724407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43306
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66368
intermediate stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01137
Uterine corpus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.736
umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.154491
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5698-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38656
hsa-miR-1178	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61085
Lung squamous cell carcinoma_LUSC_TCGA-43-8115-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.368
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6163
NCIH1650	Achilles Cell Line Gene Essentiality Profiles	1.0	1.66024
GSE150688_2_v_0_ursolic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r2 part of the ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10345
PMC11125956__F8	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K42605555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06503
TALL-1	GDSC Cell Line Gene Expression Profiles	1.0	2.35038
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66918
MJ	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ovarian cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4482
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
TARDBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60271
glial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062471
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Baoec	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
COX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07343
metal ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31358
Telomerase holoenzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.007
CRCGN008_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.202
Lung squamous cell carcinoma_LUSC_TCGA-85-8049-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64811593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49651
allotropic	GeneRIF Biological Term Annotations	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52602
BRD-K19830171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40227
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.218715
Lung adenocarcinoma_LUAD_TCGA-99-7458-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49046
Peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.834
abamectin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52011
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.053
PMC10845297__F3	PFOCR Pathway Figure Associations 2024	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17492
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044504
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.989
PMC4729482-pone.0146505.s001.xlsx-Sheet1-chRCC_positively_associated_with_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
amplification	GeneRIF Biological Term Annotations	1.0	null
SHARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50295
BRD-K48691065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.846
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44798
BRD-K56131419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47566
KDM5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40401
Bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.126
Gut cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.348
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06417
ovary	HPA Tissue Gene Expression Profiles	-1.0	-1.1132
BRD-K76193256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06698
treg	GeneRIF Biological Term Annotations	1.0	null
ghost	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275444
intracellular signaling cassette	GO Biological Process Annotations 2025	1.0	null
decreased locomotor activity	IMPC Knockout Mouse Phenotypes	1.0	null
CAL33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92608
Lung adenocarcinoma_LUAD_TCGA-05-5425-01A-02R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immune system phenotype	MPO Gene-Phenotype Associations	1.0	null
Bile duct adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381379
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
HSPB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34596
Brain Lower Grade Glioma_LGG_TCGA-DU-5853-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76932
Primary Cutaneous Anaplastic Large Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
cell surface	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.294007
Rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.647
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60537
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908727
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54698
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
BRD-K59095205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43443
GSE115363_3_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Coelom	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0182
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3326-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSU	CCLE Cell Line Gene CNV Profiles	1.0	2.24544
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
astroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067674
Peritonitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
blind uterus	IMPC Knockout Mouse Phenotypes	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4551
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.13416
Large B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
BRD-K50976856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03881
relapsing-remitting multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93484038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11017
Uroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
BRD-K47020544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05251
BRD-K53548389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28172
Thymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.806
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33864
memory t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.798958
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
sclerosing	GeneRIF Biological Term Annotations	1.0	null
peptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
Gamma delta T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.982
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286026
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.443
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19502
Bladder Urothelial Carcinoma_BLCA_TCGA-R3-A69X-01A-22R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	GeneRIF Biological Term Annotations	1.0	null
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Langerhans cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.927
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07796
Non-Convulsive Status Epilepticus	DisGeNET Gene-Disease Associations	1.0	null
LM3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
Parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.772
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34809
cholangitis	GeneRIF Biological Term Annotations	1.0	null
Epstein-Barr virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
umbilical cord blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226926
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37578
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862956
interleukin-7 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.605
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46197
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7092
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.142
rectum_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.966487
GPCR ligand binding	Reactome Pathways 2014	1.0	null
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054853
divalent inorganic cation homeostasis	GO Biological Process Annotations 2015	1.0	null
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
C-C chemokine receptor activity	GO Molecular Function Annotations 2025	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.034
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
External side of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39621
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.513677
rifamycin-sv	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73748
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0304
LZTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9566
Perturb_17048_KD_BATF3_SRP230607	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.94397
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10727
cellular metal ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00379
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17558
LYRM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.95925
HNF1B_OE_GDS1499_253_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
regulatory t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.798541
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01312966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04898
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77051
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.84544
Lung adenocarcinoma_LUAD_TCGA-91-6835-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atherosclerosis	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6481-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03775
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7731
BRD-K48213854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57416
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33578
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5111
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05871
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.004
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874893
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.72
intermediate stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34131
apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.338884
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
intracellular	GeneRIF Biological Term Annotations	1.0	null
CYFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45773
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.86275
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1776
thymus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.57082
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56474
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042997
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	0.833723
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.910269
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
Brain Lower Grade Glioma_LGG_TCGA-HT-A615-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integrin alphaM-beta2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40706
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08894
RAB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38822
encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.310652
BRD-K44878051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50554
Hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.777
Nuclear telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.866
ABHD17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37783
OBF-1_NULL MUTATION_GDS3473_571_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
th2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.026
peritoneal macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21883
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3544
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43535
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
autoimmune	GeneRIF Biological Term Annotations	1.0	null
possibility	GeneRIF Biological Term Annotations	1.0	null
igg4related	GeneRIF Biological Term Annotations	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.26385
ERBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67811
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055632
ABHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90799
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88042
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.022
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5939
MM1S	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.20073
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989542
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.25991
abnormal immune tolerance	MPO Gene-Phenotype Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.225
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03107
GSE221577_4_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2017
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_11_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_11493_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.73162
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Kupffer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.474
mephenytoin-6158	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21015
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04767
SNB19	CCLE Cell Line Gene CNV Profiles	1.0	1.43563
Peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.586
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9373
GSE129402,GSE129405_1_v_0_tcf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72032
ZNF736	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60448
Extracellular space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.374
MOLT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
BRD-K97106314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36816
Signaling by GPCR	Reactome Pathways 2024	1.0	null
BRD-K29969800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02552
MOLT-4	GDSC Cell Line Gene Expression Profiles	1.0	1.7077
BRD-K58756877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16288
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62131
Superior olivary complex, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16396
Melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.662
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QO-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39567
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.37425
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4967
GPCRs class A rhodopsin like	WikiPathways Pathways 2024	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.085881
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
hypersensitivity reaction type iv disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.097364
USF2	ENCODE Transcription Factor Targets	1.0	null
Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.173082
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21493
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intermediate stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06432
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08899
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.14187
16455954-Table2	GeneSigDB Published Gene Signatures	1.0	null
Lymph vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.986
Lamina propria	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.865
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.161
abnormal eye morphology	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
Right Ventricular Failure	DisGeNET Gene-Disease Associations	1.0	null
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29546
CLRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.198
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6601
SUDHL4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72384
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.862
Autoimmune hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8638
obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.21998
BRD-K10196668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75116
BRD-K31874013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2725
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37492
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09139
Integrin alpha4-beta7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.163
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.00695
Lymphoid follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.443
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21165
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diffuse Large B-Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
PMC7786291-Table_1.xlsx-Table_S1-Supplementary_table_1_ETV7-related_genes_in_the_TCGA_SKCM_data_set_ETV7	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal immune system physiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K01100412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07013
BRD-K00057967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48558
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.47121
factors	GeneRIF Biological Term Annotations	1.0	null
connecting stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151069
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.58939
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81306
Th2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.246
EKVX	GDSC Cell Line Gene Expression Profiles	-1.0	-2.09682
BRD-K10696228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79594
HEC1B	CCLE Cell Line Gene CNV Profiles	1.0	1.93259
epidermal	GeneRIF Biological Term Annotations	1.0	null
Stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.96
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11574
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-BRCA_AND_CESC_AND_UCEC_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_7_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
result	GeneRIF Biological Term Annotations	1.0	null
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39338
BRD-K47538257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13973
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00034
Signal Transduction	Reactome Pathways 2014	1.0	null
ccl1i309	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4539	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K49029187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80425
BRD-K96103104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42183
Parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80536
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.993
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71725
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46984
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.123
BRD-K64147309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08363
Submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.162
RELA_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Memory T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.33
Perturb_5789_KO_Tnfrsf11a_SRP103818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.00127
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260267
Pulmonary Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.580828
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28053
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13377
Sezary's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
Trunk	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181274
PMC8985862-Table3.XLSX-OTP-BRCA1_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36654
signal transduction	GO Biological Process Annotations 2015	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.215
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12617
elevated	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15978
ROS50	DepMap CRISPR Gene Dependency	1.0	3.93565
Colon adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5336
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.5283
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K62892366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77697
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.29493
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.901
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6818
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.04398
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.54488
NCIH1694	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03801
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K67874412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28107
helper	GeneRIF Biological Term Annotations	1.0	null
tolllike	GeneRIF Biological Term Annotations	1.0	null
brain cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065918
Macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.6
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11663
superficial stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12229
Chromatin silencing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15243
WSCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
clipping	GeneRIF Biological Term Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8625-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15518
Pilocarpine	CTD Gene-Chemical Interactions	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9167
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K07895476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.129
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.307757
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5781
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20689
ATM_KD_GSE54268_663_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50364
erythroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166654
BRD-K46942548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03987
Adult Anaplastic Large Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63777
Transitional cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
NUDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17696
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23459
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17557
DAUDI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.867686
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adult T-cell leukemia/lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
SKNAS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59034
phagocytic	GeneRIF Biological Term Annotations	1.0	null
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173405_3_v_0_dmba_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
T-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
Anaplastic large cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.518
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.8076
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
Bonemarrow	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08063
DRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24981
M1 macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.988
TPST2	Pathway Commons Protein-Protein Interactions	1.0	null
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
ZCCHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21933
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45848
Prostate adenocarcinoma_PRAD_TCGA-EJ-5522-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
Follicular dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1254
BRD-K56013842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43924
LOUNH91	DepMap CRISPR Gene Dependency	1.0	3.21194
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30704
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
KRAS.300_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077634
BICD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06204
liminal part of r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50364
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44576
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
Large granular lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.438
under	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11098888__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08756
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.127
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57801
leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.32009
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.282
BRD-K16663346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27784
Gastrointestinal allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39348592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82186
Thymic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
CCL1	DGIdb Drug Targets 2026	1.0	7.56171
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03135
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.9646
BRD-K39681206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27748
Fc-gamma receptor III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.60108
BRD-K34808207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6462
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SETDB1	ChEA Transcription Factor Targets	1.0	null
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
critical	GeneRIF Biological Term Annotations	1.0	null
PBMC cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.599
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0633
Ventral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97476
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69809
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69009
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965343
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57471
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
BRD-K51411441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09781
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RANBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70862
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01266
vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.085687
mantle zone of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0437
psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.514956
BICR56	CCLE Cell Line Gene Expression Profiles	1.0	1.34985
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13972
Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54981
viral envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.575912
r1 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04239
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6028-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.513677
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11087
VMCC-I	DGIdb Drug Targets 2026	1.0	7.56171
Acute leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.07066
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31716
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08056
arachidonic acid-443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cul4B-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prior	GeneRIF Biological Term Annotations	1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22812
Tissue resident memory T(TRM) cell_Blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K94742710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37587
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06907
VMIP-I	DGIdb Drug Targets 2026	1.0	7.56171
BRD-K11987248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08246
EW-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.777
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24711
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Grand Mal Status Epilepticus	DisGeNET Gene-Disease Associations	1.0	null
FURIN_Deficiency_GDS3512_568_mouse_T-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.137
NCIH2196	CCLE Cell Line Gene Expression Profiles	1.0	1.6399
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12792
TFEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5687
sex chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.129103
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.671
spleen	GTEx Tissue Gene Expression Profiles	1.0	0.919462
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ADGRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07298
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.696581
BORC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15351
th2	GeneRIF Biological Term Annotations	1.0	null
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.810468
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.5415
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7337
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80162
smooth	GeneRIF Biological Term Annotations	1.0	null
BRD-K92749855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2256
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86371068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48231
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
NCIH2085	CCLE Cell Line Gene CNV Profiles	1.0	2.79214
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52602
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28746
BW-5147 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.731031
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11113
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04108
phlebitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.219057
BRCA1	ENCODE Transcription Factor Targets	1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65687
pbmc cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501965
ATAD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45112
PMC3827940-2045-3329-3-12-S1.docx-1-Supplementary_Table_2_Minor_allele_frequencies_MAF_and_p-values_for_comparison_of_genotype_frequencies_Z9001_genotyped_whites_n_273_versus_non-whites_n_58_1_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
r2 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3257
PMC9013323-13577_2022_685_MOESM9_ESM.docx-12-AEBP1_AEBP1	Rummagene Transcription Factor Associations 2026	1.0	null
g-protein coupled peptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.22884
Midbrain, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05843
TECPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20374
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.09451
HUH7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54292
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33744
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47344
ALDH1A2_KO_GDS4836_289_mouse_posterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cancer	GAD High Level Gene-Disease Associations	1.0	0.298214
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52344
cefoperazone-5424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54066
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K18519621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40146
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.044
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66591
YWHAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1702
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24625
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35881
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23927
Hepatic stellate cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.292
TENT4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
erythrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176304
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399492
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34205
20460173-ImmPortAntimicrobials	GeneSigDB Published Gene Signatures	1.0	null
meclofenoxate-3605	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229299
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.066
Uterine carcinosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
IgA immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.594
Primary sclerosing cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14457
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06578
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56761
raises	GeneRIF Biological Term Annotations	1.0	null
BRD-K28752165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91832
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29586
MMP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18616
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.156
chronic	GeneRIF Biological Term Annotations	1.0	null
preferentially	GeneRIF Biological Term Annotations	1.0	null
cell chemotaxis	GO Biological Process Annotations 2025	1.0	null
Ink	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.073873
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
telomere-telomerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.34
Chronic Obstructive Airway Disease	DisGeNET Gene-Disease Associations	1.0	null
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24711
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29118
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.03875
P12ICHIKAWA	CCLE Cell Line Gene Expression Profiles	1.0	1.97026
UACC893	DepMap CRISPR Gene Dependency	1.0	4.7705
skin	GeneRIF Biological Term Annotations	1.0	null
Food allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
BRD-K58194737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15101
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.55164
EEF2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69715
Spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.55
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
Adult acute lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4728-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	2.66363
chemokine	GeneRIF Biological Term Annotations	1.0	null
adrenal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150713
Lymphoproliferative syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
NFIC	ENCODE Transcription Factor Targets	1.0	null
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043994
immune	GeneRIF Biological Term Annotations	1.0	null
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
Epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.96
identification	GeneRIF Biological Term Annotations	1.0	null
endometriosis	GeneRIF Biological Term Annotations	1.0	null
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81638
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03229
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18274
abnormal eye morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE211177,GSE211178_0_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.13816
procarbazine-2971	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oral squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1106
Sarcoidosis, Pulmonary	DisGeNET Gene-Disease Associations	1.0	null
Medication use (thyroid preparations)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.03979
cytokine receptor activity	GO Molecular Function Annotations 2023	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43123
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23769
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.339
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
CRCGN016_MCF10A.WT.HP_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13388
Thymus-naive regulatory t cell	Tabula Sapiens Gene-Cell Associations	1.0	4.95264
Adult Diffuse Large B-Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32921
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40516
BRD-K87053028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09368
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K18984088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05308
Fruit allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
BRD-K24734706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24279
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11949
IRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88158
201T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Airway Disease	DisGeNET Gene-Disease Associations	1.0	null
PMC4609150-13073_2015_228_MOESM2_ESM.xlsx-TP53-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38656
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21415
BRD-K15863674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04079
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukemia, lymphocytic, chronic, b-cell	GAD Gene-Disease Associations	1.0	null
cd4	GeneRIF Biological Term Annotations	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6803
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989542
CEP131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20703
Chloroplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
Perturb_8069_KD_SFPQ_SRP281189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.74517
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RC-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.736
Sarcoma_SARC_TCGA-DX-AB2T-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS513	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32659
BRD-K38588505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15989
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052051
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
BRD-K20203758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17334
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GX-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inorganic ion homeostasis	GO Biological Process Annotations 2015	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr3_39373114_C_T_b38	GTEx eQTL 2025	1.0	1.87694
Lung squamous cell carcinoma_LUSC_TCGA-63-7022-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	2.9382
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71734
Igg4-Related Sclerosing Disease	DisGeNET Gene-Disease Associations	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.261
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7668
CCDC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4798
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180367
16536878-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
pathology	GeneRIF Biological Term Annotations	1.0	null
GSE253056_0_v_1_erythropoietin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6571-01A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head and neck squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089388
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04239
Th1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.946
Lung squamous cell carcinoma_LUSC_TCGA-39-5030-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30964167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40588
Ovarian serous cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
Acute Myeloid Leukemia_LAML_TCGA-AB-2816-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21897
[<sup>125</sup>I]CCL1 (human)	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06781
BRD-K25304254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31409
Thymic medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25155
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
Immune system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.826
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37287
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.87832
Diffuse large B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1863
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19845
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.418861
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15959
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50156
appendices_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.08986
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49527
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.945746
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06051
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.141226
umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185424
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSN1	CCLE Cell Line Gene CNV Profiles	1.0	1.48915
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.786
BRD-K41684304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39168
Lung squamous cell carcinoma_LUSC_TCGA-21-1076-01A-01R-0692-07,TCGA-21-1076-01A-02R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic ductal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
697	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.18165
Lung squamous cell carcinoma_LUSC_TCGA-34-5232-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TREX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90668
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079686
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.93385
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.301
T98G	Achilles Cell Line Gene Essentiality Profiles	1.0	1.60407
BRD-K10545066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01354
KASUMI1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.18226
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63489
lateral part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55534
Brain glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
BRD-K64194889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30881
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078866
DYNC2I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05314
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92667
STAT1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5359-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.261
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4637-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
appendices_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.859419
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5163-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
GATA1_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3261
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
combination	GeneRIF Biological Term Annotations	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
639V	CCLE Cell Line Gene CNV Profiles	1.0	1.3345
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K97128200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10186
EVSAT	DepMap CRISPR Gene Dependency	1.0	2.75593
T-lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
Replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.742
BTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05649
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.269
Rectum adenocarcinoma_READ_TCGA-DC-6158-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A3OU-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9364625__F3	PFOCR Pathway Figure Associations 2024	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.2774
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9971
Herpes Nos	DisGeNET Gene-Disease Associations	1.0	null
Alveolar macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
BRD-K63008302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52552
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06987
HCC70	DepMap CRISPR Gene Dependency	1.0	4.25944
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85822
ZIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0904
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.08717
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6922
fish	GeneRIF Biological Term Annotations	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32759
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78972
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041108
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25366
BRD-K26941844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31681
Peritoneal macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.351
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10212
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K50876388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2239
High endothelial venule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.84
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
ZNF552	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68176
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64328
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53975
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89266
GSE215086_4_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11564
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39534
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5547
side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.1555
CDK5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48425
BRD-K93032100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93816
Immunological synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.34
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3031
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.106
KCTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69071
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27914478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04295
CCL8	DGIdb Drug Targets 2026	1.0	1.51234
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Thymic medullary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
BRD-K58005972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68663
Corper	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
ATF2	ENCODE Transcription Factor Targets	1.0	null
mucosal mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268828
mantle zone of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13649
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0017
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11781871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71511
Mature T-cell and NK-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.768
selective	GeneRIF Biological Term Annotations	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49067
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.091
PCCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44838
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AC-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45471
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23846
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.503926
20460173-ImmPortCytokineReceptors	GeneSigDB Published Gene Signatures	1.0	null
Integrin alpha4-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.882
Calcium	CTD Gene-Chemical Interactions	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62789
Chemokine signaling pathway	KEGG Pathways 2026	1.0	null
erkdependent	GeneRIF Biological Term Annotations	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181871
Myeloid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.422
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
DDX3X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86359
mantle zone of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55825
Mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.345
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13993
JVM3	CCLE Cell Line Gene Expression Profiles	1.0	1.53142
PTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
Arsenic	CTD Gene-Chemical Interactions	1.0	null
FUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66544
GSE225101,GSE225102_0_v_1_nmda_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5503
non-hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.342372
interleukin-3 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7435-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.86339
eosinophilic pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.443171
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965343
Genital mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.87
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156342
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.184
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83059
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74847
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.247
Primary cutaneous T-cell non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
Peritoneal mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
cellular_component	GO Cellular Component Annotations 2015	1.0	null
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	1.67225
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Allergic Asthma	DisGeNET Gene-Disease Associations	1.0	null
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
t69-brown-adipose_female_2w	MoTrPAC Rat Endurance Exercise Training	-1.0	-8.39934
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77846
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69607079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54455
Allergic Enteritis	DisGeNET Gene-Disease Associations	1.0	null
Nonparenchymal liver cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.487
RELA_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67755
SAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1199
SP1	ENCODE Transcription Factor Targets	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057037
connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.670333
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.789241
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE137914_0_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67732
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22968
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1004
Integrin alpha1-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.782
extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.392388
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.4743
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03995
intermediate stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04108
Mac-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31538
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9331
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9377
NFATC1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.08703
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05805
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9726
FBXL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84608
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14046
MRFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
JHUEM1	DepMap CRISPR Gene Dependency	1.0	3.44844
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS944T	CCLE Cell Line Gene CNV Profiles	1.0	1.35219
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9002
NUPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
SPI1	ENCODE Transcription Factor Targets	1.0	null
alveolar macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215928
KPNYS	DepMap CRISPR Gene Dependency	1.0	4.08546
REH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45878
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BRD-K56149020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0303
BRD-K45811188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28429
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77509
BRD-K58028568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48189
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
inflammatory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616586
GSE137914_4_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54914
r3 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06569
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97193
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	12.4721
Signaling by GPCR	Reactome Pathways 2014	1.0	null
BRD-K73364700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50753
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IE-A3OV-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551298
GSE102269_1_v_0_clpp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33988
biological adhesion	GO Biological Process Annotations 2015	1.0	null
Cell trailing edge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
CD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
PIK3R4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99065
Sm-like protein family complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.592
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.416
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
BRD-K82226238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04917
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22735
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JE-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7706
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51J-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10865529__F5	PFOCR Pathway Figure Associations 2024	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744
terminal loop	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.524704
MT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23430426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3435
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14229
Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA42-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plasmacytoid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
heterogeneous	GeneRIF Biological Term Annotations	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59983
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Decidual stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86221
Bladder Urothelial Carcinoma_BLCA_TCGA-LC-A66R-01A-41R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4542
RNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92939
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9165
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
asthmatics	GeneRIF Biological Term Annotations	1.0	null
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
Paraganglioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sites	GeneRIF Biological Term Annotations	1.0	null
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42884
Extrachromosomal DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69209
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.639
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.145
Saos-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.97995
G alpha (i) signalling events	Reactome Pathways 2014	1.0	null
EPHA4_drugactivation_229_GSE26523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.80641
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-2.55046
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SLC25A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03983
Acute Myeloid Leukemia_LAML_TCGA-AB-2994-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3276511__F2	PFOCR Pathway Figure Associations 2023	1.0	null
VMRCLCD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63958
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.12734
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15794
HPAFII	DepMap CRISPR Gene Dependency	1.0	2.07075
OCILY3	CCLE Cell Line Gene CNV Profiles	1.0	1.39924
17638852-Table2	GeneSigDB Published Gene Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KO-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81406
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.48324
cation homeostasis	GO Biological Process Annotations 2015	1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Xylanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.761862
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64226
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23619
H-NS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K89532826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04785
cytokine-mediated signaling pathway	GO Biological Process Annotations 2015	1.0	null
SMG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50819
MAX	ENCODE Transcription Factor Targets	1.0	null
calcium ion homeostasis	GO Biological Process Annotations 2015	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2767-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26479
BRD-K00920341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35163
UBE2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72376
SU8686	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22859
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
Peritoneal exudate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
MAP3K20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34614
BRD-K02793474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71512
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CAKI1	DepMap CRISPR Gene Dependency	1.0	4.66373
Bile duct carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
Spindle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
PK8	DepMap CRISPR Gene Dependency	1.0	9.76569
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
CBX8	ENCODE Transcription Factor Targets	1.0	null
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060641
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fibrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02008
BRD-K41033343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92965
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52344
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	2.13544
WNT_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Hiv Infections	DisGeNET Gene-Disease Associations	1.0	null
cf2th	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cell surface	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.358
GSE211177,GSE211178_8_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15616
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Plasma membrane signaling receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.173
USP2_KO_GSE43517_20_mouse_kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_17736_KO_Ikkb_SRP315113	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.5681
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07124
HDLM-2	GDSC Cell Line Gene Expression Profiles	1.0	1.99806
CCL4	Pathway Commons Protein-Protein Interactions	1.0	null
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K99985506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15309
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
host	GeneRIF Biological Term Annotations	1.0	null
BRD-K23440419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58064
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46835
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Thymus lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
Vaginal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86808
ALLSIL	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170054
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viral membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.554732
623 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
ccl1ccr8	GeneRIF Biological Term Annotations	1.0	null
IgA immunoglobulin complex, circulating	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
ZNF383	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74839
carbimazole-2437	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.062
c5mj	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.253
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383124
dexamethasoneinduced	GeneRIF Biological Term Annotations	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8425
derived	GeneRIF Biological Term Annotations	1.0	null
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31538
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62904
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.735
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8708
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12864
BRD-K82432417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.97207
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
GSK3A_knockdown_205_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.34015
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.809386
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.471539
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26441
MXI1	ENCODE Transcription Factor Targets	1.0	null
Bladder carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49955
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G protein-coupled chemoattractant receptor activity	GO Molecular Function Annotations 2025	1.0	null
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19505
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13583
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
Lung adenocarcinoma_LUAD_TCGA-95-8039-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin-regulatory t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.535773
Natural killer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.438
Eosinophilic esophagitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
BRD-K99847716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18598
Lung squamous cell carcinoma_LUSC_TCGA-85-7699-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
Perturb_11947_KO_IRF4_SRP096865	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.80048
Mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95382
Lung adenocarcinoma_LUAD_TCGA-44-6775-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063509
BRD-K48183516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08065
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89659
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965343
Molluscum Contagiosum	DisGeNET Gene-Disease Associations	1.0	null
PMC3276511__F2	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K92795658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38396
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.884
d10.g4.1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
Extrinsic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.894
HCC15	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09345
MHC protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
RENT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
BRD-K08300592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59785
Histiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.514
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.322
Hypereosinophilic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.944
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.66657
brain cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070473
GPCRs, Class A Rhodopsin-like(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
NCI-H2029	GDSC Cell Line Gene Expression Profiles	1.0	1.62743
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24514314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44638
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
Bone marrow-derived dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
central	GeneRIF Biological Term Annotations	1.0	null
HEXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3704
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Telomerase catalytic core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPCN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5896
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.261
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19W-06A-41R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLGALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8327
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.04685
TIMM10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03412
Lung adenocarcinoma_LUAD_TCGA-MP-A4T4-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mucosa-Associated Lymphoid Tissue Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.135765
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99671
BRPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
r5 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00132
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interstitial nucleus of the zona limitans	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34131
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7826
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217685_0_v_1_ddx20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ancestral	GeneRIF Biological Term Annotations	1.0	null
JAK2_activemutant_72_GSE21842	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.9376
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
monocyte-derived dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.623043
SH3D21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98034
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.272
CREB1_01_04	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.95843
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61648
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25004
CTCF	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83606
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68799
hsa-miR-3614-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52063
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1604
Glycine cleavage complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.553
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94728
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
pre-T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30078
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
calcium	GeneRIF Biological Term Annotations	1.0	null
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
cellular chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12118
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.481
Lung adenocarcinoma_LUAD_TCGA-50-5049-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4642	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
astrocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075206
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73F-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
BRD-K91043938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4603
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42798
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.006
GSE127970_1_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPZ_02_176	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.24793
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.162
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6673
GSE101546_2_v_1_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
BRD-K52921974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43025
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2021
Uveal melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042066
BRD-A69110668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68837
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64715
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
VPS26B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88578
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-3.15264
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CUEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17697
Tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.725
Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32439
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
macroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063839
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4823830-ncomms11171-s2.xlsx-GATA3_upregulated_genes-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
Plastid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
Small Lymphocytic Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319498
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4641-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34816161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07275
ccl7	GeneRIF Biological Term Annotations	1.0	null
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.639
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57447
BRD-K83369119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01465
PMC8111493__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-A75607876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03369
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74625
GSE132313_1_v_0_fosl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.737214
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.162
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07576
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91596
Peyer's gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
BRD-K85101688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51592
Decidual cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
ISGF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
Meningeal Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
A-CA-04-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.5796
BRD-K90048234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66495
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.336336
Lung squamous cell carcinoma_LUSC_TCGA-66-2755-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42181022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21097
ZNF143	ENCODE Transcription Factor Targets	1.0	null
P12-ICHIKAWA	GDSC Cell Line Gene Expression Profiles	1.0	2.16972
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52448
squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065863
CCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61385
BRD-K61316494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06266
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.348
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059044
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.449947
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6561
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6759
HS683	Achilles Cell Line Gene Essentiality Profiles	1.0	1.83725
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
NUDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79989
GPCR downstream signalling	Reactome Pathways 2024	1.0	null
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14959
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
ventral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35079
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89607
BRD-K94647035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12485
BRD-K05074020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55466
Hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.83
Lymphoma, Non-Hodgkin	HuGE Navigator Gene-Phenotype Associations	1.0	null
Cervical squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
SLC41A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33273
BCL11A	ENCODE Transcription Factor Targets	1.0	null
cytokine cytokine receptor interaction	KEGG Pathways	1.0	null
oral cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107629
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.44181
into	GeneRIF Biological Term Annotations	1.0	null
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96251
PMC9178120__F2	PFOCR Pathway Figure Associations 2024	1.0	null
nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.60108
Lymphedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08861
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412391
Chronic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.899
Childhood Anaplastic Large Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57364
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pulmonary	GeneRIF Biological Term Annotations	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
MAPK1_knockdown_112_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.096
lungs	GeneRIF Biological Term Annotations	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35398
BRD-K27293696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30635
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RELA_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thorax	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
rasmapk	GeneRIF Biological Term Annotations	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.821
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057789
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44367
T84	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72507
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055917
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0893
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42989
Hodgkin's lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peripheral blood lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31716
Peptide GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
BRD-K41133627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25709
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953541
PRNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37635
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.11809
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33791
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5115
TCIRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60988
PFKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78668
BRD-K50045638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33163
PDXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36826
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4790-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22087390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11186
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81716
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	2.11495
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044093
keratinocytes	GeneRIF Biological Term Annotations	1.0	null
NCIH2126	CCLE Cell Line Gene Expression Profiles	-1.0	-2.51357
t69-brown-adipose_female_4w	MoTrPAC Rat Endurance Exercise Training	-1.0	-5.812
ROVA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
MYC	ChEA Transcription Factor Targets	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06798
Rectum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.21501
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
within	GeneRIF Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88335
MON1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0845
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81958
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
Lsm2-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.389
liminal part of r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04502
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047523
USP2_KO_GDS5079_25_mouse_kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5055
W-13-643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.074062
SCAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18779
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
mbl2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
BRD-K44944875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0103
Adrenal cortex cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56567
Lung adenocarcinoma_LUAD_TCGA-38-7271-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chromosome, telomeric repeat region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.934
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966533
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
BRD-K26508889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03033
NCIH810	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3658
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42698
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54505
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7585-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.664
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6916
Skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
periphery	GeneRIF Biological Term Annotations	1.0	null
t69-brown-adipose_female_1w	MoTrPAC Rat Endurance Exercise Training	-1.0	-2.9094
initiation	GeneRIF Biological Term Annotations	1.0	null
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.261
Lung squamous cell carcinoma_LUSC_TCGA-22-4596-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10241773__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.129
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.64357
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.674259
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TU-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transfected	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.09664
ACT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.272
Pneumonia, Pneumocystis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Ovary adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
THUMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46398
PMC9859931-mmc5.xlsx-MSC_ADP_pred-proteins-Protein_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88933
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37971
SELENOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33247
ASPC1	DepMap CRISPR Gene Dependency	1.0	3.65533
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
Ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
Acute Type B Viral Hepatitis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K11013450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1518
tcdd	GeneRIF Biological Term Annotations	1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52304
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57434
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34334
Lung adenocarcinoma_LUAD_TCGA-MP-A4TI-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETDB1-19884255-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
umbilical vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.198365
Cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
EZH2	ENCODE Transcription Factor Targets	1.0	null
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
SET2	DepMap CRISPR Gene Dependency	1.0	2.91159
CRCGN011_HEPG2_24H:B16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02195
J82	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51369
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.291
Mycosis fungoides	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
SERHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7542
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08996
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHLDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59752
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Kidney Chromophobe_KICH_TCGA-KN-8434-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22145792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40135
gl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell adhesion	GO Biological Process Annotations 2015	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04543
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4733-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pulmonary eosinophilia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.387423
J-RT3-T3-5	GDSC Cell Line Gene Expression Profiles	1.0	1.79273
BRD-K41690760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3456
Complete Atrioventricular Block	DisGeNET Gene-Disease Associations	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908727
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5243-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulated	GeneRIF Biological Term Annotations	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511384
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88783
Systemic Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
null cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250627
GSE139239_3_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99289
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDLM2	CCLE Cell Line Gene Expression Profiles	1.0	2.29844
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81222
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.894739
virion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.258381
ROCK_INHIBITION_GDS3944_461_mouse_Forebrain astrocytes - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.326281
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPST1	Pathway Commons Protein-Protein Interactions	1.0	null
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.24548
Prostate adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65753
glioblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079718
bronchoalveolar lavage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.529113
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6419
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.826
BRD-K32063762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35614
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0535
PPP1R13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44994
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.860999
KE37	CCLE Cell Line Gene Expression Profiles	1.0	1.74917
ANKRD16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8419
abnormal behavior	MGI Mouse Phenotype Associations 2023	1.0	null
Skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.665
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.04511
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74138
Uterus-t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.762279
cutaneous t cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.285444
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0707
MRPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
vascular	GeneRIF Biological Term Annotations	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1538
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.440274
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63566
microglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.535042
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
hsa-miR-1228	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
r3 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06569
NSUN5P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CFTR_Deficiency_GDS1843_192_mouse_Lungs - Animals examined at 6 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K34755514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02359
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965343
EFO-21	GDSC Cell Line Gene Expression Profiles	-1.0	-1.88496
Integrin alphaE-beta7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.066
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.48893
ARVCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97977
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
HCC2814	Achilles Cell Line Gene Essentiality Profiles	1.0	1.01289
Uterine body mixed cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.728389
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58382
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69176
PHYKPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79277
BDCM	CCLE Cell Line Gene Expression Profiles	1.0	1.58171
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03596
Null cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.43
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8297
BRD-K88849270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18385
T84	CCLE Cell Line Gene CNV Profiles	1.0	1.94728
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.537
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.097
acquired immunodeficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.590558
G protein-coupled chemoattractant receptor activity	GO Molecular Function Annotations 2023	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874893
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2295
Abdominal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.53376
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0136
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91359
BRD-K58025976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1321
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.095517
GSE153341_2_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tumor necrosis factor receptor superfamily complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.364
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21176717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56407
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058516
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25046
PMC4823983__F5	PFOCR Pathway Figure Associations 2023	1.0	null
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30859
Lung Diseases	CTD Gene-Disease Associations	1.0	1.02485
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Chemokine receptors bind chemokines	Reactome Pathways 2024	1.0	null
type	GeneRIF Biological Term Annotations	1.0	null
BRD-K24848743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35521
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0097
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94W-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72645
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Fra-1_KO_GDS5078_403_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.52903
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ccr8	GeneRIF Biological Term Annotations	1.0	null
SERPINB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92333
B-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.424
BRD-K89637993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43216
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43921
haloperidol-4427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	14.92
Uveal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
chemotaxis	GO Biological Process Annotations 2015	1.0	null
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15832
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
ccr8i309	GeneRIF Biological Term Annotations	1.0	null
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2024	1.0	null
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39625
naive	GeneRIF Biological Term Annotations	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8641
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48477
natural killer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267791
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0714
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.84147
PMC8615762__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
Adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088869
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71861
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	1.36715
FOXM1	ENCODE Transcription Factor Targets	1.0	null
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
cd4positive	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4438	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
bc96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
NB4	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.21375
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1975
KMCH1	DepMap CRISPR Gene Dependency	1.0	2.34912
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56682
Thymic dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
Platelet dense tubular network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ki-1+ Anaplastic Large Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97155
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50647
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_B-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8198
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41639
GSE149903_3_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22965
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chromosome 11P11.2 Deletion Syndrome	DisGeNET Gene-Disease Associations	1.0	null
demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.537344
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08454
i309	GeneRIF Biological Term Annotations	1.0	null
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46468
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
helper t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.964631
ALK_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.71818
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12016
BAZ2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.105
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90939315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45633
Smc5-Smc6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.259
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.836
ZC3H12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1726
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.176635
LINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2986
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32188
SLC25A44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10241
Dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.803
upregulating	GeneRIF Biological Term Annotations	1.0	null
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SHREC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.69
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
almost	GeneRIF Biological Term Annotations	1.0	null
divergence	GeneRIF Biological Term Annotations	1.0	null
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	1.84966
Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_933_KD_TLX1_SRP132967	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.79521
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1_KD_GDS2720_478_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-A61522392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18527
pre-B-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
MAZ	ENCODE Transcription Factor Targets	1.0	null
Peptide ligand-binding receptors	Reactome Pathways 2014	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hmgn1_KO_GDS5010_406_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.130204
DUXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
Linear element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
r4 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00876
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FLO-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
interleukin-10 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
METTL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41421
BRD-K67632894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47512
Fc receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.357
PMC9174882-EMMM-14-e15816-s002.xlsx-ThCell_GeneSigs-GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_UP_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26596
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
Oral apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09721
Viral protein interaction with cytokine and cytokine receptor	KEGG Pathways 2026	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.10739
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cutaneous lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49341
axis	GeneRIF Biological Term Annotations	1.0	null
SLC8B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71178
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06468
Chemokine signaling pathway(Mus musculus)	WikiPathways Pathways 2014	1.0	null
PRDM14-20953172-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K73548235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41808
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0212
BRD-K41185648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41147
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7373-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43049540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19371
MC-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86221
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CTAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61345
c8166	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18305
RCM1	DepMap CRISPR Gene Dependency	1.0	7.96275
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2689
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1465
Vaginal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60769
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
CALR_KO_GDS3680_149_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
autoimmune response	MPO Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
y-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240216
Labial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
post-spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
Stomach carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.723
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.261
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23227
BRD-K90733601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13062
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39241
SEM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90896
BRD-K92167240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69873
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.552
mantle zone of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07708
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2415
Interstitial lung disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K55104181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64197
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48697
Petit Mal Status	DisGeNET Gene-Disease Associations	1.0	null
Esophagitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
mycosis fungoides	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.42364
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Multiple Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
Regulatory T(Treg) cell_Breast_Human	CellMarker Gene-Cell Type Associations	1.0	null
Cytokine cytokine receptor interaction	WikiPathways Pathways 2024	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08829
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.95753
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	3.3937
MAFK	ENCODE Transcription Factor Targets	1.0	null
Disease	Reactome Pathways 2014	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59615
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45848
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18076
Perturb_9484_KO_Tcf7/Lef1_SRP251706	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.80428
BRD-K44402256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26668
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.941
RUNX3	ENCODE Transcription Factor Targets	1.0	null
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00101
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03741
FLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77218
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89985
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5871
Phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.556
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9929
Basophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.949
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9172
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
decreased thigmotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
Signal Transduction	Reactome Pathways 2024	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU-139	GDSC Cell Line Gene Expression Profiles	1.0	1.50281
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75812
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K89638177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80816
BRD-K96978561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49944
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10388
STAT5A	ENCODE Transcription Factor Targets	1.0	null
BRD-K07351191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97494
MHC class II protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of Darkschewitsch	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35591
M2 macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.109
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
BRD-K75976016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08925
T-cell adult acute lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
BANF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75243
TES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16584
FHL2_Deficiency_GDS3344_596_mouse_Spontaneously immortalized embryonic fibroblasts (EFs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)	Reactome Pathways 2014	1.0	null
BRD-K17705318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24761
Eczema	DisGeNET Gene-Disease Associations	1.0	null
Eosinophilia	DisGeNET Gene-Disease Associations	1.0	null
Hypersensitivity reaction type IV disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.140653
intermediate stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06569
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.404418
SEC31B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25044
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.619255
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.154
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
NA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
Uropod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.70442
Chemokine receptors bind chemokines	Reactome Pathways 2014	1.0	null
BRD-K48020855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43977
COPG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92505
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4823
MC1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19267
Lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.845
12077300-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
Perturb_9806_KO_EBF4_SRP381947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.2751
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59746
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36153
BRD-K02548315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09053
TET1	ChEA Transcription Factor Targets	1.0	null
regulatory	GeneRIF Biological Term Annotations	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
Adrenal gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2328
CCL17	Pathway Commons Protein-Protein Interactions	1.0	null
activated	GeneRIF Biological Term Annotations	1.0	null
PMC9589293__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K12431811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2653
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97296
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.169
Pheochromocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04644
BRD-K41135617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19218
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6826
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6982
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92216
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.224204
u-87mg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.272997
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.138787
PMC7767006__F12	PFOCR Pathway Figure Associations 2023	1.0	null
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58096
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.120539
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03068
ZNF821	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92802
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pericardial mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
PAX5	ENCODE Transcription Factor Targets	1.0	null
bronchial mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.747515
immune system process	GO Biological Process Annotations 2015	1.0	null
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46616
PRR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67898
PMC6874977__F3	PFOCR Pathway Figure Associations 2024	1.0	null
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95741
BRD-K55414200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0378
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8656
BICR31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45095
Sarcoma_SARC_TCGA-VT-A80J-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3088
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61431
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55701
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16455954-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0855
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.42511
CCDC51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60792
18922855-Table1	GeneSigDB Published Gene Signatures	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42866
RCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47132
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55534
LS513	CCLE Cell Line Gene Expression Profiles	1.0	1.43564
functions	GeneRIF Biological Term Annotations	1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.94293
Lung squamous cell carcinoma_LUSC_TCGA-60-2715-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytolytic granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.019
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3228
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	2.47066
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ductcentred	GeneRIF Biological Term Annotations	1.0	null
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78526
altered susceptibility to autoimmune disorder	MPO Gene-Phenotype Associations	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39972
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
antagonist	GeneRIF Biological Term Annotations	1.0	null
ZKSCAN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55312
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreatitis	GeneRIF Biological Term Annotations	1.0	null
Autoimmune thyroiditis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.261
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A4EO-06A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatitis B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCA1_Knock-in_GDS1756_233_mouse_Forebrain tissue - 4 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2718
CHD2	ENCODE Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04479
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AGTRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09838
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26374
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.987271
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03443
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20063
Perturb_11492_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.87178
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17309
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6774
myeloid	GeneRIF Biological Term Annotations	1.0	null
Peptide GPCRs	WikiPathways Pathways 2024	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052543
Granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.489
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56373119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15753
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anaplastic large cell lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09284
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63777
Uterine corpus endometrial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.811
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.35906
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02008
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08899
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77Q-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchial epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12733
Peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.029
Stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.966
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7661-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.732
PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-13_CD7_CD1a_DEG-DEG_L2FC_1_0_FDR_0_05_REL	Rummagene Transcription Factor Associations 2026	1.0	null
mediates	GeneRIF Biological Term Annotations	1.0	null
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432991
STBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78429
stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305722
ATR-ATRIP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
B4GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83391
Esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.544
Peritoneal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.568
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66878
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC chemokine receptor 8	InterPro Predicted Protein Domain Annotations	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06015
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74778
Melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
gefitinib-541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.52188
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
Peeling Skin Syndrome	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94440323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03462
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
ELOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10351
CP-320650-01-3905	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09631
indometacin-453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
apoptosis	GeneRIF Biological Term Annotations	1.0	null
ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35442
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876133
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103376
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11132
bw-5147 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.704764
PMC3979852__F8	PFOCR Pathway Figure Associations 2023	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.647721
T-cell acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
ccr8mediated	GeneRIF Biological Term Annotations	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2145
Lymphopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
USP6NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31602
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.852402
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00067
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52854
Myelomonocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
Complex Partial Status Epilepticus	DisGeNET Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46R-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plasma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.685
PMC9396374-Table_4.XLSX-AR_related_genes_from_OMIM-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88367
Sarcoma_SARC_TCGA-DX-A1L4-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Common cold	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96638
PGA1	DepMap CRISPR Gene Dependency	1.0	3.05525
NCIH2172	CCLE Cell Line Gene CNV Profiles	1.0	1.8824
RPMI-8402	GDSC Cell Line Gene Expression Profiles	1.0	1.9366
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.15971
Epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.004
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06219
Keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.827
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78086
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24265
CHD1	ENCODE Transcription Factor Targets	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908727
APOBEC3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37142
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
Diabetic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271952
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33291
[125I]CCL1 (HUMAN)	DGIdb Drug Targets 2026	1.0	7.56171
GARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.635
GSE130475_1_v_2_thpo_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.15334
GSE216538_1_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.582
cutaneous lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.302337
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
496100473_TCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.10593
cellular divalent inorganic cation homeostasis	GO Biological Process Annotations 2015	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL5	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10521
RSV-A2_24Hour-KO_RSV_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.62513
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MEG01	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51978
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKNO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.30768
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tlr4	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1078
Mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.717
Fetal Death	CTD Gene-Disease Associations	1.0	1.22469
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00981
Subtelomeric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
Non-odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
JURKAT	CCLE Cell Line Gene Expression Profiles	1.0	1.42908
ELMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51616
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
SW1271	CCLE Cell Line Gene CNV Profiles	1.0	1.49701
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6236
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mikulicz disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE137914_2_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62S-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04052
CELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08673
MYOC_OE_GDS1640_269_mouse_retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7672-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25695
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
Adult T-cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23411
Sarcoma_SARC_TCGA-DX-A3U6-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypothalamic lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13649
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06432
allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162109
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
BRD-K94191869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25659
Thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
CHO-K1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.945155
GSE172490_0_v_1_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08696
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287447
Leukemogenesis	DisGeNET Gene-Disease Associations	1.0	null
Glioma	HuGE Navigator Gene-Phenotype Associations	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.816
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61614
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.433
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277549
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
Lung adenocarcinoma_LUAD_TCGA-97-A4M7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4701-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7838-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
monocyte-derived dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K38282015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09843
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Umbilical cord blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97898
CRCGN008_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2343
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77954087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08496
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58538
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5373-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rad51C-XRCC3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.319
Skin-cd8-positive, alpha-beta memory t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.762279
BRD-K49461735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26992
EP300	ENCODE Transcription Factor Targets	1.0	null
Goblet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.359
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891157
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.56833
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FADS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72995
C14orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60747
diffuse large b-cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.528323
Hyperplasia	CTD Gene-Disease Associations	1.0	1.10803
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69767
HUT78	CCLE Cell Line Gene Expression Profiles	1.0	2.49349
primary cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.849165
Lung adenocarcinoma_LUAD_TCGA-J2-8192-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11964_KO_BATF_SRP401628	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.9172
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32759
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45924
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
HUT-78 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
CD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24435
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1341	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81779
GPCRs, Class A Rhodopsin-like(Mus musculus)	WikiPathways Pathways 2014	1.0	null
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4558
leading	GeneRIF Biological Term Annotations	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35588268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51965
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.369
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03498
NFIA_Deficiency_GDS2775_639_mouse_Embryonic brains (at E18)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
F36P	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.19036
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QM-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06893
FUT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74353
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0469
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.516
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042297
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9807_OE_EBF4_SRP381947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104904
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77265
HSPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76502
MMP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43359
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54743
accessory entopeduncular nucleus (post-migratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5121
FYTTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66816
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.92744
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YAPC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99385
Eosinophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.303
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.54234
COX8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32703
PGM2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47571
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876133
Spinal cord disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.12219
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11164
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.07788
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
IgE immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.119
Perturb_15969_KO_Gata3_SRP357829	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.06159
normoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166654
BRD-K90827020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87731
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25115
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04108
CRCGN014_HEPG2_3H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06832
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24165
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.907
CRCGN014_HEPG2_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12227
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.513677
progressive multifocal leukoencephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.274021
BRD-K94881465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16208
Perturb_3270_KO_H1_SRP234772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87073
GSE120781,GSE174528_4_v_1_ctcf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
aspergillosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.130858
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0623
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953541
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07204
20460173-ImmPortChemokineReceptors	GeneSigDB Published Gene Signatures	1.0	null
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09111
Spliceosomal snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.491
encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.190476
icSARS-Cov_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63265
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29546
Endometriosis	DisGeNET Gene-Disease Associations	1.0	null
peduncular paraventricular area of PHyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0785
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JH-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.559652
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62821
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45271
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5846
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder urothelial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
Mesenteric lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.752
ion homeostasis	GO Biological Process Annotations 2015	1.0	null
EFF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.616
Cervix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
Immunosuppression	DisGeNET Gene-Disease Associations	1.0	null
esophagitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.127488
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292436
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6223
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46836
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40015
GABARAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61522
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15125
BATF	ENCODE Transcription Factor Targets	1.0	null
astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0687
CCRF-CEM	GDSC Cell Line Gene Expression Profiles	1.0	1.69799
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7868
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42866
TSC22D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54937
biological regulation	GO Biological Process Annotations 2015	1.0	null
BRD-K73319967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24753
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101527_3_v_2_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63323
DND41	CCLE Cell Line Gene Expression Profiles	1.0	1.49128
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.55603
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
astroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068173
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96163
neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454512
Dinoflagellate epicone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.066
BRD-K56231599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11643
links	GeneRIF Biological Term Annotations	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.2545
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51495
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06015
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
Decidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.58175
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
ZK 756326	DGIdb Drug Targets 2026	1.0	7.56171
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99301
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
urinary bladder	HPA Tissue Gene Expression Profiles	1.0	1.38184