association	dataset	threshold value	standardized value
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14073
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Methoxychlor	CTD Gene-Chemical Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77606
gtp-rho binding	GO Molecular Function Annotations 2015	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22797
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36123
mantle zone of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11693
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833691
Retrosplenial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01564
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36338
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3023
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51472
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
positive regulation of cellular component biogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35348
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28944
mapk cascade	GO Biological Process Annotations 2015	1.0	null
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2496
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.873
GSE236511_1_v_0_ngfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34338
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048366
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858473
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41128
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78446
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2BBE1	DepMap CRISPR Gene Dependency	1.0	2.02183
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.898277
Cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.642
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828164
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.524
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSPA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32633
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04883
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.99153
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03807
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.17629
pseudopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.385436
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.72955
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Split septin rings	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.247
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072558
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE213632_1_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHCR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23088
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25921
SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-2726-SM-3P61A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25335
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1867
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1911
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05423
IM9	DepMap CRISPR Gene Dependency	1.0	3.42979
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_83_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237753
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917318
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.03754
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950458
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47528
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25625
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895427
USP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0777
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1781	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84895
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.49457
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884838
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95071
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.221
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of actin filament-based process	GO Biological Process Annotations 2015	1.0	null
GTEX-S4Q7-0926-SM-4AD5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06769
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.902823
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229032
Amyotrophic neuralgia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.158502
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20835
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881321
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01593
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937569
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01195
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875057
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58142
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878831
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08432
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061537
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86178
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.48474
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TT1TKB	DepMap CRISPR Gene Dependency	1.0	2.4522
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993862
Perturb_10848_KO_Pparg_SRP289705	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.07633
colonrectum_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.21439
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5262-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1645
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.935652
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05423
ONCODG1	DepMap CRISPR Gene Dependency	1.0	7.03724
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51126
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900213
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41124
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02196
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of actin filament length	GO Biological Process Annotations 2015	1.0	null
Perturb_9658_KD_SKIDA1_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.35883
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062681
SNU878	CCLE Cell Line Gene CNV Profiles	1.0	1.51169
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73426
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093219
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.06274
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56753
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75204
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.944197
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01114
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.216
HT1376	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7366
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846365
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40146
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
increased basophil cell number	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47012
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73483
GSE210476_9_v_5_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hypercholesteremia_Hepatic Tissue_GSE3889	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.73721
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA5_GATA5	Rummagene Transcription Factor Associations 2026	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911128
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49994
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65875
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4232
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.966623
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047427
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31573
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.914094
TTC642	DepMap CRISPR Gene Dependency	1.0	7.6853
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88485
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03953
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	1.66998
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26272
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31067
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of actin filament polymerization	GO Biological Process Annotations 2025	1.0	null
Posterior parietal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10745
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERBB2_knockdown_236_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.60018
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843144
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03266
MAX	ENCODE Transcription Factor Targets	1.0	null
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.23776
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854772
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46544
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00145
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35495
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00042
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
mRNA_TCF3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26585
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05893
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1618
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76383
PTEN_KD_GDS2958_99_human_A431 - EPIDERMOID carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02546
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8812
subpretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21324
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A59Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28821
HUH6	DepMap CRISPR Gene Dependency	1.0	3.86005
PMC11266547-41598_2024_67808_MOESM1_ESM.pdf-50-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	215.274
Phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.873
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12055
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43634
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q3-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1786
Parabrachial nucleus, lateral division, central lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24385
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.202
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4082364-supp_ddu111_ddu111supp_table14.xls-Tabelle1-Table_S14_comparison_MSC_WT1Wilms3_-_top_100_genes_down-regulated_vs_wtWT1_-_top_100_down-regulated_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04818
GSE134191_6_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01686
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54774
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.87492
cellular bud	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.65001
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50807
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_6_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01162
SU8686	CCLE Cell Line Gene Expression Profiles	1.0	1.44409
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.18707
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33034
enzyme binding	GO Molecular Function Annotations 2015	1.0	null
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74747
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978464
ETS1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825425
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15536
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A678-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02071
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21572
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.6461
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55736
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976165
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130956_2_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1975	CCLE Cell Line Gene CNV Profiles	1.0	1.8579
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25173
VPS45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99373
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35622
18338247-SuppTable4B	GeneSigDB Published Gene Signatures	1.0	null
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897655
SW837	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.00598
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12115
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
sublayer 6a of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54946
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68549
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-3_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PKBalpha_KO_GDS1784_194_mouse_Embryonic fibroblasts (MEFs) - 2h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
prostate	GTEx Tissue Gene Expression Profiles	1.0	0.933287
PMC11252802-pnas.2322203121.sd15.xlsx-Sheet1-TRP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16196
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996392
AGS	DepMap CRISPR Gene Dependency	1.0	3.01604
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AB-01B-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.46908
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08223
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.755135
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0823
SALL4-18804426_ESC-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830797
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223698
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02137
SLVL	DepMap CRISPR Gene Dependency	1.0	2.14875
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8914074-Table1.XLSX-S8-Alternative_splicing_events_from_corneal_epithelial_samples_and_peripheral_blood_samples_of_KTCN_patients_VSX1	Rummagene Transcription Factor Associations 2026	1.0	null
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88309
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868357
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0892
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13371
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841913
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	2.25375
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0708
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22208
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4776-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38995
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0208
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21745
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875764
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_121_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-1426-SM-3MJHC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33121
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A8YN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11443
OAW42	DepMap CRISPR Gene Dependency	1.0	3.65683
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
PSMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61534
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15488
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157S_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	1.0	1.0813
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16298
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.372
Ganglioneuroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90795
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.4642
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1259
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13336
cell cortex part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.532488
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1364
Atrophy	CTD Gene-Disease Associations	1.0	1.38469
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45168
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.09681
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WI-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898335
AP-3 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06802
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3281
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.86
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76829
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.754217
Superior colliculus, optic layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28887
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824248
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06737
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12306060-13023_2025_3945_MOESM1_ESM.pdf-10-PATZ1_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111247_14_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_1_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
at1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961532
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01194
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11839
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18058
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_112_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.844386
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839194
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GSE231829_0_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sirolimus_mus musculus_gpl1261_gse21755	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14046
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cos-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.525166
GTEX-XUW1-1926-SM-4BOP1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47923
PMC4082364-supp_ddu111_ddu111supp_table12.xls-wtWT1_down-Table_S12_MSC_wtWT1_-_top_100_genes_down-regulated_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX4_01_260	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.92244
biological_process	GO Biological Process Annotations 2015	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
monocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220378
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RMUGS	CCLE Cell Line Gene CNV Profiles	1.0	1.48527
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34567
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14086
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.160456
ID1_01_134	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.84215
cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.515308
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51222
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endocervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2063
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984139
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43498
Peripheral nervous system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BA-59-EN38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36748
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3163
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.52111
Neoplasms	CTD Gene-Disease Associations	1.0	1.18259
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59142
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01165
SLC25A37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79591
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51222
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.2938
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29997
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30367
Primary somatosensory area, nose, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46544
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894338
Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42981
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24619
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.17222
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57856
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950226
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	367.991
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02814
GSE92589_2_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085281
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836121
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24564
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colon	HPA Tissue Gene Expression Profiles	1.0	1.00846
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.2415
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.977505
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871561
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.264215
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200558
Paralysis	CTD Gene-Disease Associations	1.0	1.14404
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39206
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10143
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	1.0	1.37478
Cdc42 effector	InterPro Predicted Protein Domain Annotations	1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.36005
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09946
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.945
PMC7217064-IJC-146-3354-s004.xlsx-Table_S5-Supplementary_Table_S5_Genes_significantly_upregulated_in_OC2-transfected_AGS_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CDC42	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-XUZC-1226-SM-4BRVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35509
10min_PPase_inhibitors vs ctrl_Hepa1-6 (Mouse) [18846507]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04502
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059358
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109191
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.08
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54968
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.10838
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37558
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.28682
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of protein polymerization	GO Biological Process Annotations 2023	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21804
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01564
GCIY	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949156
LPCAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58397
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62469
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.5161
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29156
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393064
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8872
GSE261563_7_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP1_KO_GDS1606_772_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36216
TCF12	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.12323
MITF_01_24	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.77147
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04186
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61756
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842792
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inhibin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04603
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02504
PHF8	ENCODE Transcription Factor Targets	1.0	null
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36757
PMC4366019-pone.0116096.s005.xlsx-Primary_positives_NOT_retested-Unnamed_8_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of cellular component size	GO Biological Process Annotations 2015	1.0	null
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080056
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
MDAMB157	CCLE Cell Line Gene CNV Profiles	1.0	1.47906
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907011
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964779
DUSP1_KO_GDS1606_773_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870822
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978596
Perturb_12146_KD_Hdac4_SRP343455	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30333
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.475
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949307
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.44274
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.963
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47S-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045413
Perturb_9147_KD_CBLL1_SRP307037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.37755
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34777
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.551
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
ERBB2_knockdown_235_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.78317
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97948
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85957
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053023
TCCPAN2	CCLE Cell Line Gene Expression Profiles	1.0	1.79543
S462	DepMap CRISPR Gene Dependency	1.0	2.04037
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055499
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HBS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67484
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.364
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61597
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04107
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834409
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05115
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE238005_7_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21815
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02546
HCC1588	CCLE Cell Line Gene Expression Profiles	1.0	1.68495
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_lowerRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
positive regulation of actin filament polymerization	GO Biological Process Annotations 2015	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942303
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11266547-41598_2024_67808_MOESM1_ESM.pdf-50-ENSG00000178573_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69589
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828737
Bacteroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
positive regulation of pseudopodium assembly	GO Biological Process Annotations 2015	1.0	null
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05725
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.8156
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S3XE-1226-SM-4AD4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36168
Neurological pain disorder_CNS - Spinal Cord (MMHCC)_GSE18803	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.654118
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995851
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858473
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955373
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1057
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14232
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94135
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54122
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XYKS-2226-SM-4E3IU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31866
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_122_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923201
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.19159
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	2.04801
Hypertension	CTD Gene-Disease Associations	1.0	1.06116
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
laticifer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.517678
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.35763
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01227
G402	DepMap CRISPR Gene Dependency	1.0	2.89324
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08179
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1775
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00308
GSE193177_1_v_2_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.116
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17376
CNFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04028
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTNNB1-20615089-FETAL_BRAIN-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.8687
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
KPNYS	DepMap CRISPR Gene Dependency	1.0	8.71363
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-0_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0443
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14751
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0572
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.139
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20386
jnk cascade	GO Biological Process Annotations 2015	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5889
TRIM28	ENCODE Transcription Factor Targets	1.0	null
Perturb_17652_KD_DNMT3A_SRP367237	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.29564
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.049
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56031
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Contractile actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.78
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41599
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33794
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58668
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09234
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09811
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LASV_FML29_8hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.19495
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Craniofacial Abnormalities	CTD Gene-Disease Associations	1.0	1.0766
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44289
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ6-0926-SM-3P5ZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70791
Cellular bud neck septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11164
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04967
LN-18 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
bacteroid-containing symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20963
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12647
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.48541
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19769
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213565
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.1197
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41817
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046285
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH684	CCLE Cell Line Gene Expression Profiles	1.0	1.69372
signal transduction	GO Biological Process Annotations 2015	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02994
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967903
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32138
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08821
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924833
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858908
regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13899
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61572
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34603
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15677
PMC5794192-ppat.1006868.s001.xlsx-S1B_Table-S1B_Table_Differentially_expressed_genes_between_IRF8-sg2_and_NC_cell_lines_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39394
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rt4	HPA Cell Line Gene Expression Profiles	1.0	1.10014
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02013
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12946
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964059
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.71815
MAPK6/MAPK4 signaling	Reactome Pathways 2024	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGSF1 deficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.07447
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11112
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased lean body mass	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15751
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2948
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24564
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-1326-SM-48TZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58952
18614019-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38591
RI1	CCLE Cell Line Gene CNV Profiles	1.0	1.47262
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47283
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
XPodNet - protein-protein interactions in the podocyte expanded by STRING(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29354
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79341
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850849
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
QF-05-OL72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349618
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3541
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1496
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888728
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30367
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31468
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79387
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10745
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20367
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866044
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03502
small GTPase binding	GO Molecular Function Annotations 2025	1.0	null
angular gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948165
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958481
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35244
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887476
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.412
Perturb_14110_OE_C11orf53/Pou2f3_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.37923
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36257
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50157
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881423
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077023
germinal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.404797
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
phosphate-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10627
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5195
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953267
GNAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42551
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-KLF5_targets-target_gene_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Trachea-tracheal goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	1.01311
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50758
regulation of anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of anatomical structure size	GO Biological Process Annotations 2015	1.0	null
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19773
GGPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27174
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10914
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053204
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044854
SALL4-18804426-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58287
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14332
AC-71-YF45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217676
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9128
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23184
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51094
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84458
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.42238
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.420428
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86836
Root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	1.71339
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
TTC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78652
GADD45G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22502
Rectum adenocarcinoma_READ_TCGA-DC-6681-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053395
GSE99187_1_v_0_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Perturb_18150_KO_Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.31322
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26795
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18773
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
PMC4082364-supp_ddu111_ddu111supp_table9.xls-Tabelle1-Table_S9_MSC_WT1Wilms3_-_top_100_genes_down-regulated_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6207
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06504
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08844
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
GTEX-WFG8-1626-SM-4LVMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1379
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03337
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51207
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34811
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54071
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062998
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
colonrectum_b	HPA Tissue Sample Gene Expression Profiles	1.0	0.848312
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08294
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23516
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241801
bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.451078
GSE201454_1_v_2_ftcd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78344
Endocytic patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Myosin II filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.533
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.05864
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of actin polymerization or depolymerization	GO Biological Process Annotations 2015	1.0	null
obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.410161
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11709
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC42	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24967
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044002
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3574
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.27504
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZMIZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04654
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ALAS2_OE_GDS2118_74_human_Blood	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880246
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044102
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851892
Actin cortical patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
Perturb_9700_KO_TREX1_SRP355094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84254
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825774
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of actin filament polymerization	GO Biological Process Annotations 2023	1.0	null
Plastid nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35119
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.479312
brain	HPA Tissue Gene Expression Profiles	-1.0	-0.992272
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
Lung adenocarcinoma_LUAD_TCGA-69-7763-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-47-IB34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244515
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15639
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EIF4EBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13687
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23988
NOTCH_INHIBITION_GDS2794_61_human_MOLT4 (T-cell acute lymphoblast leukemia) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71728
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237837
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_11488_KO_Foxp1_SRP158103	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.2794
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42263
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_lowerRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47358
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30973
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114385
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834513
GSE144481,GSE144483_0_v_3_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.950084
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1762
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.85939
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79735
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908683
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58211
skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.1386
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6145-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-DESeq_MSC_vs_fibroblast_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12009
Parabrachial nucleus, lateral division, dorsal lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07812
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.949176
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20026
GSE190186,GSE190188_8_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35682
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02191
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
YD15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53665
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.60501
septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.1429
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.315
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70057
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cytoplasmic side of nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.8686
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09586
Intestinal juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
Septin cap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.707
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Lung squamous cell carcinoma_LUSC_TCGA-39-5039-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98136
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.59421
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05511
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21572
Anterior group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41169
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.46174
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32465
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	4.48054
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.988217
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Origin recognition complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.989
TCF3	ENCODE Transcription Factor Targets	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.20295
LB831-BLC	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.347
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876226
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215086_5_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
biological regulation	GO Biological Process Annotations 2015	1.0	null
Cholestasis, Intrahepatic	CTD Gene-Disease Associations	1.0	1.06442
myc_20940306_e13dot5_erythroblast_purified_from_liver_gof_mouse_gpl6885_gse18558	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.353033
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25061
A204	CCLE Cell Line Gene Expression Profiles	1.0	1.39082
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30835
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1709
NCIH1993	DepMap CRISPR Gene Dependency	1.0	3.17366
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.88919
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31782
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830053
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4366019-pone.0116096.s005.xlsx-Primary_positives_NOT_retested-Primary_S6P_positives_NOT_selected_for_retesting_with_the_4_individual_RNAi_used_in_the_intial_screen_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6054
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70782
Inflammation	CTD Gene-Disease Associations	1.0	1.07022
RL	CCLE Cell Line Gene CNV Profiles	-1.0	-2.46321
PK1	DepMap CRISPR Gene Dependency	1.0	2.15807
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59013
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_125_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914643
GSE124375_13_v_12_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13955
lateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08641
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04603
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059559
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28203
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930305
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7203
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.06008
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09275
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	2.63393
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	203.123
furan	CTD Gene-Chemical Interactions	1.0	null
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5138
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82568
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SMU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62264
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.1887
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06693
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04472
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927446
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.61295
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
erg_19359602_huvec_lof_human_gpl570_gds3557	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.485867
CB-25-VR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227194
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11219
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15195
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5UA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12779
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368046
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63686
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE261563_2_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCIH2126	DepMap CRISPR Gene Dependency	1.0	2.77196
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20697
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98894
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05374
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77973
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25173
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE205316,GSE205317_2_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95002
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3813
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67279
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.941174
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.023
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05611
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sublayer 6b of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28887
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01303
PPP1R26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44599
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.142
Allergic Rhinitis (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
SARS-dORF6_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.09611
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kmp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.2125
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63979
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04979
Sarcoma_SARC_TCGA-X9-A973-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.529618
GATA4-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MD-49-BL92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235342
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
OB-17-DQ74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209163
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33458
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Somatosensory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2558
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC78	CCLE Cell Line Gene CNV Profiles	1.0	1.40314
layer 5 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08404
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_47_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17572
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56893
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.176374
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.18568
Bone	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22175
abnormal coat/hair pigmentation	IMPC Knockout Mouse Phenotypes	1.0	null
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.016
regulation of actin filament polymerization	GO Biological Process Annotations 2015	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78789
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L6-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06023
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.44872
MOSPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87088
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930423
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2483_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07425
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69993
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.979844
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043206
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08058
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855196
STAT5A_02_182	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.61471
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-11_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0651
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
b-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.300533
Parabrachial nucleus, lateral division, ventral lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23214
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46504
hca-f cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.51759
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82985
SNU16	CCLE Cell Line Gene Expression Profiles	1.0	1.51527
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_upreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05439
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.86667
ACSL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11773
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357842
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56503
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62824
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11773
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.07878
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
17638893-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63138
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2492_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92948
GTEX-QDVJ-1326-SM-48U1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17694
OE19	CCLE Cell Line Gene Expression Profiles	1.0	2.74547
Actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.774
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884081
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.02896
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92489
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52141
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047833
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993048
Septin filament array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.475
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.25868
CCK81	CCLE Cell Line Gene Expression Profiles	1.0	1.57807
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842076
Interstitial lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.987017
Learning Disorders	CTD Gene-Disease Associations	1.0	1.34576
PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00966
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13521
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8961
positive regulation of plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2025	1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39289
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR16	DepMap CRISPR Gene Dependency	1.0	5.25627
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16732
GTF2F1_02_157	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.49354
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058284
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43498
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEx Lung 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	6.34744
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64772
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S10_DGEA_IKZF1-Supplemental_Table_10_Differentially_expressed_genes_between_IKZF1_and_all_other_subcluster_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
increased eosinophil cell number	MGI Mouse Phenotype Associations 2023	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836709
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10702
GTEX-XGQ4-1226-SM-4AT67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32638
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44164
GSE217685_0_v_1_ddx20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.275445
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CL40	CCLE Cell Line Gene Expression Profiles	1.0	1.86646
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3682
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212503
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31904
ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.319328
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00145
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_64_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54968
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50613
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32622
response to stress	GO Biological Process Annotations 2015	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Cdc42 GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.908
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89501
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50508
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.837221
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.92944
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79105
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061131
hsa-miR-3924	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20014
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB3A_KO_GDS2482_706_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A460-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914344
H2BK12ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	1.37932
increased eosinophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41807
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07757
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.83905
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094009
GSE86507,GSE86509_7_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978464
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Pseudopodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19147
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937447
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17376
ras gtpase binding	GO Molecular Function Annotations 2015	1.0	null
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36337
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05753
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991527
TXNDC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06048
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GCIY	DepMap CRISPR Gene Dependency	1.0	2.01203
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79618
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061298
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01001
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A673	CCLE Cell Line Gene Expression Profiles	1.0	1.70757
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966762
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rho gtpase binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_10885_KD_Mafg_SRP165897	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.71989
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904304
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266413
Hyperplasia	CTD Gene-Disease Associations	1.0	1.3414
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.915723
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979626
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876431
Nodal marginal zone lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65988
parahippocampal gyrus, right, bank of the cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.847225
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HUG1N	CCLE Cell Line Gene Expression Profiles	1.0	2.21201
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27568
GTEX-SE5C-1526-SM-4BRWU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51962
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06558
TLCD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78666
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00683
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38929
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.06182
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13137
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37103
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Contractile vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871561
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55257
ZDHHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5661
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913104
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1984
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15366
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76605
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	1.0	3.80422
mRNA_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBFA2T3_KD_GDS4045_458_human_Non-Hodgkin's lymphoma Reh cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93219
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MM-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18986
DDX46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14252
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.19338
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07007
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Abscission zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11407
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08841
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01103
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24576
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00984
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30909
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959542
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.555
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_102_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95865
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896838
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98469
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199606_6_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70495
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847462
LMNA_02_175	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.59826
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02109
SARS-CoV MA15_Day2-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.35653
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75238
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050833
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.431932
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2585
raw-264.7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33413
GSE174383_6_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EVSAT	CCLE Cell Line Gene Expression Profiles	1.0	1.45521
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.50448
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ANKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82511
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.23552
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31913
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal coat/hair pigmentation	MGI Mouse Phenotype Associations 2023	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1301
TCCSUP	DepMap CRISPR Gene Dependency	1.0	2.84273
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32382
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21416
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69933
Lung squamous cell carcinoma_LUSC_TCGA-60-2707-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946395
GSE48812_7_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47X-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37829
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.21271
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32914
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41196
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84036
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963713
Lung squamous cell carcinoma_LUSC_TCGA-68-7757-01B-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925595
BIRC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08755
Perturb_11568_OE_SIX4_SRP166969	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.35903
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.863707
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056902
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24486
tectal gray formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12009
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07731
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.38086
HIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35929
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80706
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13128
E2F1	ChEA Transcription Factor Targets	1.0	null
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06354
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892334
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9963
Bpe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08998
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082509
EZH2	ENCODE Transcription Factor Targets	1.0	null
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15605
Parabrachial nucleus, lateral division, superior lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07227
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29631
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	312.687
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43498
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46337
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03477
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880598
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1529
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF365	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22178
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39287
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03462
GTEX-XBED-1526-SM-4AT5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92192
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	2.07393
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11606
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6988
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917814
GSE160373_1_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.21121
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.29301
mRNA_SOX2_17515932	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219928
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16521
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.23328
Perturb_5818_KO_Gata2_SRP239807	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.16381
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.840154
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34934
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00337
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30483
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pharyngeal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.830818
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85906
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10411
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917663
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07126
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.232
Lung adenocarcinoma_LUAD_TCGA-62-A46S-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11465086-mmc2.xlsx-Table_ES_1_markers_c0_LPS_Vs_Co-Gene_Expression_Data_1_markers_c0_LPS_Vs_Control_related_to_Figure_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.426
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21854
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08967
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96515
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.966868
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10011
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.853893
Perturb_10719_KO_Nrf2_SRP336215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.70368
positive regulation of cell projection organization	GO Biological Process Annotations 2015	1.0	null
Superior colliculus, motor related, intermediate gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75552
Lung adenocarcinoma_LUAD_TCGA-55-8090-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85441
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU1J-1326-SM-46MUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16641
Perturb_16442_KD_IL13RA2_SRP314695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20572
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983121
17875932-TableS4	GeneSigDB Published Gene Signatures	1.0	null
carpel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489838
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36633
estradiol_homo sapiens_gpl6947_gse27375	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839147
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1286
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090191
GTEX-WI4N-1426-SM-3LK7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00133
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SNU719	CCLE Cell Line Gene Expression Profiles	1.0	1.46776
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04496
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.49558
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98291
Perturb_8395_KD_Atoh8_SRP410862	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.39368
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922328
STAT3	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12636
mantle zone of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21702
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1762
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390044
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82696
Pain	CTD Gene-Disease Associations	1.0	1.03864
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43634
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53011
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27335
GTEX-S7SF-1926-SM-4AT5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90981
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05675
a24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder-bladder urothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	10.8696
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949802
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.23
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42263
Guanosine triphosphate	HMDB Metabolites of Enzymes	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046783
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_11_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327135
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178532_1_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17648_KO_CEP83_SRP379856	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.07828
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
isthmic part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27251
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.886922
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062375
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17438
Signaling by Rho GTPases	Reactome Pathways 2024	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.861308
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2486_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Seizures	CTD Gene-Disease Associations	1.0	1.23169
latex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.518465
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33913
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36039
SNU475	DepMap CRISPR Gene Dependency	1.0	3.64223
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58565
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72913
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T3M3	DepMap CRISPR Gene Dependency	1.0	7.06578
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912493
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
DFFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26463
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01216
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.523
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157S_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19461
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00308
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22995
positive regulation of cytoskeleton organization	GO Biological Process Annotations 2023	1.0	null
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24545
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13636
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884162
Perturb_2482_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
KLF4	ChEA Transcription Factor Targets	1.0	null
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12868
ChIP_SALL4_18804426	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.02336
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.3295
PMC9377669-tx1c00392_si_002.xlsx-1160_PS-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73829
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FUCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37505
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30835
tendon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221061
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.0058
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824574
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25173
GSE210476_11_v_5_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8399
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107031
MAFK	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PYCR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97672
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27289
GTEX-X8HC-0226-SM-4E3K1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926175
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30821
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16526_KO_Ahrr_SRP318414	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.24041
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26272
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03374
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934817
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06128
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
BXPC3	CCLE Cell Line Gene Expression Profiles	1.0	1.92598
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29286
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
macrophage cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25858
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84664
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830797
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9817
Lung adenocarcinoma_LUAD_TCGA-MP-A4T7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT4	CCLE Cell Line Gene Expression Profiles	1.0	1.87268
Cell division site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.56
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-436 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AGS	CCLE Cell Line Gene CNV Profiles	1.0	1.40817
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73226
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RCOR1	ENCODE Transcription Factor Targets	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MXI1	ENCODE Transcription Factor Targets	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44001
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06482
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181431_0_v_1_calr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU620	CCLE Cell Line Gene Expression Profiles	1.0	2.31895
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064613
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08019
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06719
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89486
cellular bud neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.726152
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
Hair follicle bulge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26388
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996049
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25387
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064844
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91498
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
k22	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38132
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30207
Perturb_8028_KO_IRTKS_SRP310479	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25721
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77572
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50668
small GTPase-mediated signal transduction	GO Biological Process Annotations 2025	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045261
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of cell projection assembly	GO Biological Process Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.929983
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	5.86402
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ganglioneuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
OB-20-LP90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26625
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8451_KD_EphA2_SRP237314	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6159
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.28667
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16941
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20926
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHK1_KD_GSE54268_666_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
regulation of actin filament polymerization	GO Biological Process Annotations 2025	1.0	null
ras protein signal transduction	GO Biological Process Annotations 2015	1.0	null
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68558
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30112
regulation of pseudopodium assembly	GO Biological Process Annotations 2015	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056099
MTREX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74826
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10143
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01564
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.339
CTNNB1-20615089-FETAL-BRAIN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MCF10A_KD-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33115
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6427
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE220520_3_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211766
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939703
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8355
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
layer 6 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7715
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24122
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980423
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30891
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.38119
HMG20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08329
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00968
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92308
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09257
duodenum	HPA Tissue Gene Expression Profiles	1.0	1.11492
GTEx Brain 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	14.2877
positive regulation of supramolecular fiber organization	GO Biological Process Annotations 2025	1.0	null
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.084879
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.3921
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052066
regulation of pseudopodium assembly	GO Biological Process Annotations 2023	1.0	null
LMNTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	485.533
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04761
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062581
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40427
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05455
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946215
DCP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16134
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00145
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Perturb_4242_KO_Sphk1/Sphk2_SRP403207	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.39331
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80372
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20569
MDST8	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.8616
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059694
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279011
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65831
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11212_KO_Cd36_SRP351120	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.86477
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.836291
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EW8	DepMap CRISPR Gene Dependency	1.0	2.27829
17297478-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06835
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7657
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-1426-SM-3LK5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08004
Lung squamous cell carcinoma_LUSC_TCGA-21-5784-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26675
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3001
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.35213
Superior colliculus, motor related, intermediate white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48845
actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.395098
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38045
Root hair tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43634
layer 6 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47117
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_ZFP281_18757296	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21402
mRNA_POU5F1_20526341	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10604
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.06114
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70085
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28487
GSE164884_2_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86345
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.0278
sublayer 6a of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28066
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38533
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52649
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
PMC7529806-41467_2020_18638_MOESM7_ESM.xlsx-Supplementary_Data_4-Supplementary_Data_4_TG_of_EPAS1_EPAS1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chaperonin-containing T-complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.14
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.16544
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12839
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18531
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39427
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTPase binding	GO Molecular Function Annotations 2025	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055699
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.573
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19996
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.186
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041342
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	4.10426
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979472
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28801
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
PMC12611713-Table2.xlsx-Sheet_1-Training_Database_AND_Validation_Database_NOT_Diabetes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53095
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178255_2_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82664
decreased lean body mass	IMPC Knockout Mouse Phenotypes	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02234
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9781_KD_Ctnnb1_SRP321923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.22637
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12714
Esophageal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MD-17-VD78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240316
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86642
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	238.612
Lung squamous cell carcinoma_LUSC_TCGA-34-5928-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_201_OE_Mir204_SRP131517	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.41022
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.952205
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05457
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02146
MAPK family signaling cascades	Reactome Pathways 2024	1.0	null
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234514,GSE234516_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46203
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE60837_6_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836214
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11407
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.912896
GSE239844_8_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_354_OE_MITF_SRP298756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
Lateral root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832197
Annuli extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
EIF4G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13919
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.952722
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12773
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.898867
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10S-01A-22R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58648
increased basophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88455
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13965
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02084
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43498
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CSTF2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56511
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.047
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15969
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24405
Perturb_8453_KD_ASGR1_SRP334678	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	2.45512
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-396-ZNF761_ZNF761	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA_01_80	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60159
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.435
Perturb_2494_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17226
ERBB2_knockdown_234_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.81532
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907025
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21112
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61239
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7913-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934769
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Necrotizing fasciitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8834_KO_MESP1_SRP345831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.32941
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34487
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66363
SNU-16	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.99583
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54699
small gtpase binding	GO Molecular Function Annotations 2015	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09582
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31594
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.48667
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.934339
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of cell shape	GO Biological Process Annotations 2015	1.0	null
Perturb_446_KD_FOXP1_SRP127520	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Cleavage furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.517
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1111
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F5-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.54
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73152
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-1826-SM-4JBIL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10699
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10068
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39747
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934841
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.43328
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35504
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36552
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23631
superficial stratum of PCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22071
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.470332
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NS-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865765
GTEX-S32W-2026-SM-4AD6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854549
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50526
Superior colliculus, motor related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80478
superficial stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09257
Weight Loss	CTD Gene-Disease Associations	1.0	1.57924
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20641
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09103
quadriplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.11393
VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28111
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.884716
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2052	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41411
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889471
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39655
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
CMTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30135
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27589
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rho protein signal transduction	GO Biological Process Annotations 2015	1.0	null
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25581
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915715
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56062
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12328
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53853
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25173
phosphorylation	GO Biological Process Annotations 2015	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A66B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A3LW-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7366
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30559
actomyosin	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.338128
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_9_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1152
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226019
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28843
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55606
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	303.688
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53549
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14717
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5362_KO_Dux_SRP237568	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.1341
PMC7974552-mmc3.xlsx-cluster_N10_marker_genes-Unnamed_0_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.117699
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945054
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903114
hsa-miR-342-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	237.036
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30313
Cellular bud neck septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231206
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5162
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08071
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06496
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.402
SW948	DepMap CRISPR Gene Dependency	1.0	2.86875
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33118
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874478
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4060771-170289.f1.pdf-309-KLF6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64071
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159967_3_v_0_arid5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cleavage apparatus septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
PMC2813300-pone.0008960.s011.xls-SOX2_targets_in_human_ESCs-Gene_Symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13238
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06825
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.093
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00652
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992472
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04878
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39807
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08647
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.47797
bone	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4083
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.62404
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00878
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10411
PC14	DepMap CRISPR Gene Dependency	1.0	4.08918
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	290.469
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871279
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225015
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6868-01B-12R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1523
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943848
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51942
AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25566
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE215086_1_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mist1_22510200_pancreas_c57bl6_lof_mouse_gpl6246_gds4341	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.39392
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34466
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.39529
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
stomach_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.873912
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MESSA	CCLE Cell Line Gene Expression Profiles	1.0	1.59382
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04402
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976356
Sperm annulus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.557
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05227
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889238
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2911
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57703
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of actin cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GSE249146_2_v_3_dusp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.895642
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14637
UMUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.51252
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.09486
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30644
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62968
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nerve compression syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.97254
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983174
Lateral meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.07026
AP5M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82543
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41707
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69196
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11788
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216757_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878356
Perturb_2480_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
signal transduction by phosphorylation	GO Biological Process Annotations 2015	1.0	null
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.31356
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-95-NR38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205737
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59615
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29217
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12658_KD_NFE2L2_SRP242008	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of protein complex assembly	GO Biological Process Annotations 2015	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SBNO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17581
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.8301
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40675
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.937378
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12113
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GS-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MI-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10361959-41419_2023_5985_MOESM1_ESM.pdf-1550-ZNF175_ZNF175	Rummagene Transcription Factor Associations 2026	1.0	null
retrosplenial cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16312
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930775
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0601
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27887
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53923
phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253248
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04565
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34266
ZNF281	ChEA Transcription Factor Targets	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30369
Perturb_10734_KO_Mettl14_SRP282531	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.0623
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851006
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5437
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14651
Fatty Liver	CTD Gene-Disease Associations	1.0	1.43974
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2134
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36123
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847242
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96353
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894338
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
LAMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21161
Perturb_10769_KO_Jnk1_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.88957
RBL1_KO_GDS1931_740_mouse_Neurospheres (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851164
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHO GTPase cycle	Reactome Pathways 2024	1.0	null
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89372
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196609
Prostate-hillock-club cell of prostate epithelium	Tabula Sapiens Gene-Cell Associations	1.0	1.42609
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Differentially_expressed_genes_DEGs_upon_CDC20_knockdown_under_37_culture_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.49296
CTNNB1	ChEA Transcription Factor Targets	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81964
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902472
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7647
stomach	HPA Tissue Protein Expression Profiles	1.0	1.36302
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.019
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906633
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32065
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25162
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30559
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67045
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929552
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.455284
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885286
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
small intestine	HPA Tissue Gene Expression Profiles	1.0	1.04307
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17012
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01972
STAT3	ChEA Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29502
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	Reactome Pathways 2024	1.0	null
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-geneID_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0528
Lung adenocarcinoma_LUAD_TCGA-80-5608-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3852
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894338
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055225
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204128
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
uterus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.886438
GSE234514,GSE234516_2_v_0_mitf_human	RummaGEO Gene Perturbation Signatures	1.0	null
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23898
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99288
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AK5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4784-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10889
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043979
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881257
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18801
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.974755
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06249
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.0804
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23739
stress-activated mapk cascade	GO Biological Process Annotations 2015	1.0	null
GTEX-S95S-0226-SM-4B656	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01146
Lung adenocarcinoma_LUAD_TCGA-86-8359-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.50722
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05691
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05888
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.596193
KIJK	DepMap CRISPR Gene Dependency	1.0	6.16983
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38208
Autosomal recessive spinocerebellar ataxia 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22705
regulation of cell morphogenesis	GO Biological Process Annotations 2015	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.706105
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
wolfram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.14942
SW626	DepMap CRISPR Gene Dependency	1.0	3.28743
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15156
a72	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-2.79089
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08284
SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.80688
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S4-Supplemental_Table_S4_Differentially_expressed_genes_between_cases_with_G-CSF-induced_pY-STAT3_DMFI_1_5_STAT3_Low_v_DMFI_1_5_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16276
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55157
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18079
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.071297
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14113
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03469
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
RUNX1_01_344	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.6107
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49186
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Myosin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.254
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26383
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39694
16293578-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
SALL4	ChEA Transcription Factor Targets	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.09892
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18956
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lung adenocarcinoma_LUAD_TCGA-55-8619-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48269
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14072
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39889
Perturb_4370_KO_TP53_SRP346812	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.50588
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Actomyosin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.866
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05544
H4	CCLE Cell Line Gene CNV Profiles	1.0	1.87516
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312479
GTEX-T6MN-1126-SM-4DM71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984759
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316951
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LT-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11074_KO_Prkcb_SRP330448	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.84802
MJ	DepMap CRISPR Gene Dependency	1.0	3.01368
Swine influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2592
GTEX-XYKS-2726-SM-4E3IC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838667
ZKSCAN1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889211
connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45967
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6495
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6642-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRIB domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209898
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080655
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
YD10B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49322
Symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.03827
TAF1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.2871
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26067
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sporulating cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WQ-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CACNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86941
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19985
LU-65	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.05336
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989633
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19874
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.903695
GSE235682_3_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.136
E2F6	ENCODE Transcription Factor Targets	1.0	null
ODC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08599
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.44132
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DSH1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.91302
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87703
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20605
SOX11_DEPLETION_GDS4801_326_human_Z138 mantle cell lymphoma (MCL) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cytoskeleton	GO Cellular Component Annotations 2015	1.0	null
Perturb_15063_OE_Trp53_SRP345823	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.6353
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4782
monocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176046
Inhibin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36892
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-dORF6_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.11596
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48758
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055303
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949354
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular response to stress	GO Biological Process Annotations 2015	1.0	null
positive regulation of plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2023	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17943
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.882442
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056651
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054714
capan2	HPA Cell Line Gene Expression Profiles	1.0	1.06783
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.946132
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32939
FF-96-HL81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211368
18332228-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967738
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857352
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39028
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37267
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.95827
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BE-57-VZ17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212296
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53905
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093794
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.158692
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00462
GTEX-RWS6-1726-SM-47JXP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945634
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33019
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71414
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40657
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-1226-SM-4DXUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77081
layer 1 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61507
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15736
PTEN_KD_GDS2958_100_human_HCC827 - NON-SMALL CELL LUNG carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE183251_1_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6145927-41467_2018_5729_MOESM6_ESM.xlsx-TF_Activity_Genesets-SNAIL_UP_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41636
GSE193177_1_v_3_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0545
PMC10534007-Table_2.xlsx-S1_overlap_MSC_up_B_V-438_common_elements_in_BFTC905_MSC_up_and_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_4_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.36302
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830797
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_27_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
KLF4-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12328
BB30HNC	DepMap CRISPR Gene Dependency	1.0	2.17964
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57895
nih-3t3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.566428
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830797
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955373
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
colonrectum_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.63576
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.22534
19798054-ST	GeneSigDB Published Gene Signatures	1.0	null
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08621
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08918
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.28919
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4734
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1435
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29334
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13717
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF4_02_04	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.45943
Septin collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
RUNX3	ENCODE Transcription Factor Targets	1.0	null
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07568
DNER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01154
ZB-72-PE17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215451
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055863
Stress fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.782
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	2.65561
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75285
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6824-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D9_vs_D15-Unnamed_2_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6529937-Table_1.xlsx-IRF1_dependent_downregulated-gene_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831258
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SW1088	DepMap CRISPR Gene Dependency	1.0	2.40338
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78966
isthmic vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35622
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42721
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042069
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08617
NB13	DepMap CRISPR Gene Dependency	1.0	2.1912
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
Perturb_18149_KO_Ikbkb/Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.47966
PAX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17143
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252811
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU1077	DepMap CRISPR Gene Dependency	1.0	2.95866
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13864
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
RBBP5	ENCODE Transcription Factor Targets	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.664
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27685
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0841
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAPPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99229
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53398
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
positive regulation of organelle organization	GO Biological Process Annotations 2015	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55624
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.66654
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05339
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13047
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01535
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.849608
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8283158-mmc2.xlsx-TCF4_Glut-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS729	DepMap CRISPR Gene Dependency	1.0	2.17969
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83765
SRSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06538
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92895
regulation of cell projection organization	GO Biological Process Annotations 2015	1.0	null
HT115	CCLE Cell Line Gene Expression Profiles	1.0	1.53187
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24564
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2821
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048777
angular gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.878721
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111035,GSE111040_10_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33938
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23194
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05158
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.049
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.551
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13399
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of CCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18773
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937447
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58006
GTPase binding	GO Molecular Function Annotations 2023	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.399023
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38745
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ATF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23106
regulation of actin filament polymerization	GO Biological Process Annotations 2023	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92217
protein binding	GO Molecular Function Annotations 2015	1.0	null
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45736
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01291
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11693
response to stimulus	GO Biological Process Annotations 2015	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GSE146247_0_v_1_sirt7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2815_KD_LSD1_SRP310243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63369
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.078
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27079
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.957155
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.971212
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238987
GSU	CCLE Cell Line Gene Expression Profiles	1.0	1.63111
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973497
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44062
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968003
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9466
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200928
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909172
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16061
GTEX-X5EB-1726-SM-4E3J7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12856
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 6 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64948
Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876431
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28716
carpal tunnel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.995283
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13621
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02338
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924194
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
FKBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37352
bladder	GTEx Tissue Gene Expression Profiles	1.0	1.00188
regulation of protein complex assembly	GO Biological Process Annotations 2015	1.0	null
CAPAN1	CCLE Cell Line Gene Expression Profiles	1.0	1.56303
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
Perturb_2490_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1946
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878027
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211954
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17307
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.73183
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55411
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.871692
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13289
UBE4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05267
MACROH2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47862
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14298
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95406
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12009
GLUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19991
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1762
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39645
intracellular part	GO Cellular Component Annotations 2015	1.0	null
bladder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.33188
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459532
17297478-SuppTable6	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23157
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8130-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949051
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30304
Ataxia	CTD Gene-Disease Associations	1.0	1.21501
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.73772
hsa-miR-3178	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	3.12259
positive regulation of pseudopodium assembly	GO Biological Process Annotations 2025	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intercostal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19089
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29946
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40773
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autonomic nervous system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913639
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral Hemorrhage	CTD Gene-Disease Associations	1.0	1.01966
endomembrane system	GO Cellular Component Annotations 2015	1.0	null
Hca-F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.442
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.84398
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00042
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81716
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.145256
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64109
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070348
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Root cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of pseudopodium assembly	GO Biological Process Annotations 2023	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039484
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TE5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41383
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21055
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2107
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_113_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.46008
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828354
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.90328
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	3.02043
Perturb_14092_KD_FOXD3_SRP051544	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1709
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4417
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00057
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57251
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824965
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UTP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63644
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20837
Perturb_18610_KO_Btnl2_SRP324170	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.13089
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25605
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15193
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.19887
Ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.117
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39551
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908365
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.09726
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.42355
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
MGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14485
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Interstitial lung disease 2	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
Wolfram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923078
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4214
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03606
HDAC2	ENCODE Transcription Factor Targets	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0178
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.874618
JPH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33496
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEx Heart 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	7.8351
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18531
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32082
GBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62636
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.17827
COA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49362
RBM34_02_141	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.93074
SNU182	DepMap CRISPR Gene Dependency	1.0	4.55044
DU4475	DepMap CRISPR Gene Dependency	1.0	4.50576
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15506
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
Retrosplenial area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16656
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36608
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.966473
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14625
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_34_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199606_6_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71727
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89754
mRNA_ESRRB_19136965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73983
diethylstilbestrol_rattus norvegicus_gpl1355_brown norway_gds2913	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99534
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06944
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07909
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.311
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24519
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30658
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53573
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.901665
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical layer of collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09214
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03808
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61625
496100630_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.815
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.049
Lateral root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE510	CCLE Cell Line Gene CNV Profiles	1.0	1.70939
HA-99-UT82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220723
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6984-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16963_OE_RAB44_SRP305964	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.17121
Agranular insular area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12965
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
OTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21573
Septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.124
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05976
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
lm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88401
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00042
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964063
Superior colliculus, motor related, intermediate gray layer, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37579
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NJ-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.13621
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875714
Growth cone membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0012
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926891
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.329
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1326-SM-4LVMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5035
GTEX-WOFL-0826-SM-3MJG1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12958
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5117
PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_KLF4_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Brachial plexus neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
parietal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22071
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939165
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPC1	CCLE Cell Line Gene Expression Profiles	1.0	1.6963
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88571
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059392
Cholestasis	CTD Gene-Disease Associations	1.0	1.12014
Perturb_2481_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.978823
GSE129465_3_v_2_phf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.259124
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840875
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92975
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64087
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0609
Memory Disorders	CTD Gene-Disease Associations	1.0	1.12668
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.992
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15161
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19122
Phagocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.858
GSE165174,GSE165175_0_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57042
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.847839
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933467
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2170	CCLE Cell Line Gene CNV Profiles	1.0	1.41801
KLF4-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39537
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.113954
GTEX-VJYA-2026-SM-4KL1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28881
GSE104022_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225481
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rho protein signal transduction	GO Biological Process Annotations 2025	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.6515
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305353
Diabetes Mellitus	CTD Gene-Disease Associations	1.0	1.01814
Supramammillary nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18574
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A-CA-04-2009(H1N1)_12Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72454
positive regulation of protein polymerization	GO Biological Process Annotations 2015	1.0	null
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844637
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34853
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04455
positive regulation of supramolecular fiber organization	GO Biological Process Annotations 2023	1.0	null
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924683
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34777
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-7173-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SARS-BatSRBD_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.94327
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	444.471
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14135
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8066
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20911
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58814
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_8-Supplementary_Table_8_ETV6-repressed_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
16166618-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01988
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29T-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inferior mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02166
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of pseudopodium assembly	GO Biological Process Annotations 2025	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05214
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858473
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27462
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	459.818
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01843
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849694
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00778
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01334
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928119
NCIH854	CCLE Cell Line Gene Expression Profiles	1.0	1.38158
Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919736
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11962
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35633
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44612
gtpase binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34413
EN1	JASPAR Predicted Transcription Factor Targets	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LS180	CCLE Cell Line Gene Expression Profiles	1.0	1.4788
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42926
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular component biogenesis	GO Biological Process Annotations 2015	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.991937
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17267
Perturb_53_KO_Zfp708_SRP186171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.03233
Fibrosis	CTD Gene-Disease Associations	1.0	1.08372
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978826
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral SC part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50624
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870967
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.99163
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874728
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12009
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01954
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
H-508	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
Perturb_13848_KO_RET_ERP126468	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01866
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
JVM3	DepMap CRISPR Gene Dependency	1.0	7.76109
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13852_KO_RET_ERP126468	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.049
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03194
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937447
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_02_190	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.6009
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17957
Connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Mitotic septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.974
style	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53267
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857145
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05779
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20273
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZM-1126-SM-4DXUB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09862
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7008
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
non-hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069373
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50632
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19735
GTEX-XQ8I-2126-SM-4BOOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65641
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14298
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969453
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0845
TTC549	DepMap CRISPR Gene Dependency	1.0	5.51321
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71774
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861592
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	2.55835
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039421
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861592
Chloroplast nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3414-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.38974
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898357
sublayer 6b of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70071
ACAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03574
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18294
MM160113	DepMap CRISPR Gene Dependency	1.0	2.07692
GSE215086_1_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2BK15ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54685
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33009
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047705
colon	GTEx Tissue Gene Expression Profiles	1.0	1.60744
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43634
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7968
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.366
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38455
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42055
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32934
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982329
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
periventricular stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27251
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.10246
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895824
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40701
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43926
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25754
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954551
PMC7373278-pone.0236187.s013.xlsx-MDA231genes_overexpressed_in_AR-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
stress-activated protein kinase signaling cascade	GO Biological Process Annotations 2015	1.0	null
regulation of organelle organization	GO Biological Process Annotations 2015	1.0	null
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934456
NCI-H250	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18346
Pseudopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829089
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.654944
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23416
TMEM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54885
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
layer 5 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83038
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21795
GSE190316,GSE190324_6_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36533
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39002
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cdc42 gtpase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.50904
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.930356
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19884
Signal Transduction	Reactome Pathways 2024	1.0	null
ANKRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39644
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336349
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824764
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24216
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37092
esr1_21713035_mcf7_lof_human_gpl570_gds4061	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.381424
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67134
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884162
MLXIP_01_03	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.178
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.58524
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15639
Microcephaly	CTD Gene-Disease Associations	1.0	1.04538
regulation of developmental process	GO Biological Process Annotations 2015	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	175.754
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0228
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3654
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3319
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14767
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59433
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98769
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.3144
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A3L1-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13971
16178058-Table5	GeneSigDB Published Gene Signatures	1.0	null
leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.124945
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948505
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80014
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895605
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36796
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875714
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00145
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25173
IRAK4_knockout_41_GSE12124	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.01881
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gin4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19549
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12368
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0393
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03477
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65537
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43498
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDC42 GTPase cycle	Reactome Pathways 2024	1.0	null
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89404
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96408
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1762
Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.174
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07679
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5671-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.827
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab8_TRIM11-KD-up_genes-Table_8_Up-regulated_genes_in_TRIM11-KD_TRIM11-KD1_Control_overlap_TRIM11-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
prostate_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.07516
Perturb_8829_KD_KCNN4_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57584
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.12906
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
positive regulation of cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07437
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44612
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MT-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25038
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876022
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00878
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAUS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77891
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEx Muscle 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	8.78186
CCDC85C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60765
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98792
filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253248
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17426248-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13737
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-VDR-Unnamed_0_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WL-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.300679
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951618
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4739-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18773
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02998
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.905298
stress fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.400527
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.06181
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066994
regulation of protein polymerization	GO Biological Process Annotations 2015	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09904
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00181
Perturb_3243_KD_UCA1_SRP124072	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.7799
Brain Diseases	CTD Gene-Disease Associations	1.0	1.05274
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64032
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_SOX2_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CMK115	DepMap CRISPR Gene Dependency	1.0	2.47479
MRPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12958
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2402
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Hair follicle dermal papilla cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.341
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42689
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49506
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17534
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14501
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.469
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46561
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.20196
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89767
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941164
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10447
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91889
gynoecium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.488276
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31311
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63544
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37362
GTEX-TSE9-2526-SM-4DXUS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00784
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927127
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02826
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2373
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.15825
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62147
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7773-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.1233
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22184
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4510-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A822-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60687
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838282
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56465
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18832
SU8686	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3465
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851049
NB69	DepMap CRISPR Gene Dependency	1.0	3.49979
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84979
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5U8-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.44447
SPI1	ChEA Transcription Factor Targets	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.905852
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.76995
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11209
Peribacteroid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.027
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19419
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86497
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00878
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19516
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4839-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19708
Psp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
PMC12802643-mmc10.xlsx-EC2-EC2_Endothelial_subcluster_2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
chr19_54443247_A_T_b38	GTEx eQTL 2025	1.0	1.04291
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4664-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
GTEX-WFG7-1726-SM-4LVME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18688
RELA	ChEA Transcription Factor Targets	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1971
site of polarized growth	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.120416
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23313
peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.465038
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Parabrachial nucleus, lateral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27659
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.04299
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A27C-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22848
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.75626
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12018
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07812
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.986919
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04854
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35471
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	1.05625
small gtpase mediated signal transduction	GO Biological Process Annotations 2015	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055856
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lamellipodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.337
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75173
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36767
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of protein polymerization	GO Biological Process Annotations 2025	1.0	null
POLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68588
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.1779
Hemorrhage	CTD Gene-Disease Associations	1.0	1.20622
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44295
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886775
smallintestine_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.24391
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate	HPA Tissue Gene Expression Profiles	1.0	0.878227
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
tretinoin_mus musculus_gpl1261_gds4294	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
small GTPase binding	GO Molecular Function Annotations 2023	1.0	null
LU65	CCLE Cell Line Gene Expression Profiles	1.0	2.85592
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3633
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871213
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09257
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948556
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10411
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97038
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXC10_HOXC10	Rummagene Transcription Factor Associations 2026	1.0	null
ARID3A_02_50	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62293
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.134
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20712
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4B-Up_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099353
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051712
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78894
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.00925
JD-62-TK68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292323
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885286
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.36302
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-1126-SM-48FDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82686
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58724
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60867
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913764
Prospore contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.85
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87454
GTEX-PSDG-1026-SM-48TCV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875519
FOXP2	ENCODE Transcription Factor Targets	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41128
KCNK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97217
CHLA57	DepMap CRISPR Gene Dependency	1.0	2.95013
inferior temporal gyrus, right, bank of mts	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863422
Large_Intestine-enterocyte of epithelium of large intestine	Tabula Sapiens Gene-Cell Associations	1.0	5.84611
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15969
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36541
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7222
SKNDZ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09248
Muscular Diseases	CTD Gene-Disease Associations	1.0	1.17728
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907054
GTEX-S4P3-1226-SM-4AD4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5262
PMC5789885-41467_2017_2812_MOESM4_ESM.xls-Supplementary_Data_1-Supplementary_Data_1_Non-cardiac_mesoderm_and_endoderm-permissive_differentiation_of_EOMES_KO_hESCs_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
CDC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63376
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.44649
positive regulation of cytoskeleton organization	GO Biological Process Annotations 2025	1.0	null
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857307
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null