association	dataset	threshold value	standardized value
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866422
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.71009
BRD-K52977489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24421
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33959
TE10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64048
limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236332
BRD-K74039237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08476
BRD-K59957885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51039
HCC33	CCLE Cell Line Gene CNV Profiles	1.0	2.59506
synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.127877
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.47159
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K73357010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62282
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.991281
ipratropium bromide-5823	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.74673
breast adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.522273
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.99606
BRD-K68084083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35979
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19912
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28108927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41215
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.979217
BRD-K65135171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49588
BRD-K82863660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12357
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fenbufen-4279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K23204256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60881
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17795
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
hilus of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52146
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74289419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77859
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987769
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.517678
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K76984291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78918
KDM4A	ENCODE Transcription Factor Targets	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.92421
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13102
BRD-K91470977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09666
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26087
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04445
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.95729
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	2.05758
PDX1-19855005-MIN6-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
collagen disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.96366
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.079332
Liver Diseases	CTD Gene-Disease Associations	1.0	1.16733
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52228
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47661
BRD-K08715020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3629
ITGA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22106
TE6	CCLE Cell Line Gene CNV Profiles	1.0	2.04651
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18674
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLI1-17442700-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H446	GDSC Cell Line Gene Expression Profiles	1.0	1.59284
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19203
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24276
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050955
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58487
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
ventral part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02975
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917682
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76672835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4452
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XD-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
set	GeneRIF Biological Term Annotations	1.0	null
sporadic breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.78066
BRD-K16228393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64241
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.17666
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1995
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
renal	GAD High Level Gene-Disease Associations	1.0	0.293278
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12139
GAMG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K82224868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13586
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02312
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.92809
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.967974
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
POU5F1	ChEA Transcription Factor Targets	1.0	null
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.01212
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.298214
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08461
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49833
BRD-K77060313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75271
BRD-K10133810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16871
BRD-K74600148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66468
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01976
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.970747
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47468
bepridil-4613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K06403738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25294
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841817
BRD-K97569931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86574
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_11_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
triglycerides	GAD Gene-Disease Associations	1.0	null
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day14-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30464
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K05868476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31541
kawain-7369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
REST_01_211	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.90547
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC6138666-41398_2018_246_MOESM4_ESM.xlsx-Sheet1-Table_S3_Nominally_significant_ZBTB20_targets_from_association_analysis_of_SAD_versus_healthy_controls_sorted_by_p-value_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224645
BRD-K14070721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56427
CACNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06672
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.923922
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45859
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11679
KP-4	GDSC Cell Line Gene Expression Profiles	-1.0	-2.20574
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05392
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.49354
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7349
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
sirolimus_homo sapiens_gpl6244_gse15703	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alprenolol-7141	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.901271
H3K27me3_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7879-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.912102
troglitazone-4456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41561756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20743
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4421
debrisoquine-6688	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.972057
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04723
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83874
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
TTI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23491
ZNF263	ENCODE Transcription Factor Targets	1.0	null
nalidixic acid-7367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.703127
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.968427
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96603
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K50941255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35292
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05733
BRD-K10058823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30955
levcycloserine-3789	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23575
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769855
BRD-K23361743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.223
mantle zone of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18526
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57522
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69021
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11771
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K91410469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14928
Prostate adenocarcinoma_PRAD_TCGA-EJ-5524-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1374
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.734
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.17295
Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30877
HUO9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10176
optic fiber layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23383
BRD-K29441085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05342
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.596058
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394197
NCI-H1694	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.043786
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.178871
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.892039
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YAPC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51813
mephentermine-3685	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26888
VACTERL association	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
cefotaxime-5830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K83684822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10531
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74999
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02534
mometasone-5116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69805
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37099
BRD-K39863565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9547
BRD-K22748970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03503
Treacher Collins syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
BRD-K25444802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18669
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2491
TCF12	ENCODE Transcription Factor Targets	1.0	null
biological adhesion	GO Biological Process Annotations 2015	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontine nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.634358
Cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04387
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37732
neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.252564
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880441
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
HLF	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.85174
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271604
NR2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16077
ECGI10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8238
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83466873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11242
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.13963
BRD-K97717496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7441
BRD-K65875972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1962
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08645
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58701
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.40815
CDH9	Pathway Commons Protein-Protein Interactions	1.0	null
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K83952475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10482
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53448
Esophageal atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
Prostate adenocarcinoma_PRAD_TCGA-G9-6332-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFE184	DepMap CRISPR Gene Dependency	1.0	2.33393
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Waardenburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
Hippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26354
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08524
BRD-K60806315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73083
nalbuphine-5820	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839082
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21986
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05658
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34499
Hmgn1_KO_GDS5010_405_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447576
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13748
granule cell layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48541
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.686502
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
high vocal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705993
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02036
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05999
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37652
major	GeneRIF Biological Term Annotations	1.0	null
BRD-K83487481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30591
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44003352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54255
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01164
CCK81	DepMap CRISPR Gene Dependency	1.0	3.73971
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55262
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.953416
BRD-K34423419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1956
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FGFR3_knockdown_173_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.94845
BRD-K14671808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38939
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72239
HCT-15	GDSC Cell Line Gene Expression Profiles	1.0	2.3569
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.955711
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46573
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0241
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16274
ZFP57-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.797
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PNU-0251126-7390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069208
pentolonium-7375	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
promazine-3752	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
oncogenesis	GeneRIF Biological Term Annotations	1.0	null
BRD-K00231307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26771
Choanal atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.113
HCT15	BioGPS Cell Line Gene Expression Profiles	1.0	1.61046
TP53_01_31	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.23934
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16206
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067493
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50638
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.84671
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
BACH1	ENCODE Transcription Factor Targets	1.0	null
BRD-K38118226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27632
medial part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39184
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.13484
BRD-K92950328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03924
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.553
BRD-K19269952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24042
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19897
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0218
CHD7	ENCODE Transcription Factor Targets	1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A2PC-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.80587
BRD-K67716105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15778
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	1.65697
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72191
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0259
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06645
BRD-K31608682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13638
BRD-K37308886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02656
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16422
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1502
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
isocarboxazid-7383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell-cell junction assembly	GO Biological Process Annotations 2023	1.0	null
19286929-SuppTable2a	GeneSigDB Published Gene Signatures	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24032
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01611
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_state_markers-AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
ventral part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17943
extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.290308
HCC2218	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040577
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84844
BRD-K18783332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35519
Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGFR	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K50593511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12446
Trichotillomania	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
OUMS23	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36753
BRD-K45811188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64921
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86584551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17144
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
trimethoprim-7377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TOV112D	Achilles Cell Line Gene Essentiality Profiles	1.0	1.15063
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01246
NCIH69	CCLE Cell Line Gene CNV Profiles	1.0	1.63238
BRD-K16525290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43147
IMR32	CCLE Cell Line Gene Expression Profiles	1.0	1.43024
chlorpromazine-5074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A83387524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47359
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8440-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell junction assembly	GO Biological Process Annotations 2023	1.0	null
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41205
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28039
BRD-K81035073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39029
Weight Loss	CTD Gene-Disease Associations	1.0	1.07093
ZNF844	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21407
BRD-K15879529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14816
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K58779593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51643
BRD-K31805261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08642
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19861
BRD-K18290923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25638
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
levcycloserine-4524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.33015
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bipolar Disorder	DisGeNET Gene-Disease Associations	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Cell junction organization	Reactome Pathways 2024	1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
mantle zone of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13638
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.281224
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.55385
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nomifensine-2062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056021
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5507
bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116053
reticular formation of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0394
BEN	CCLE Cell Line Gene Expression Profiles	1.0	2.51116
PMC10679662-mmc2.xlsx-NC-D3-ZEB2-siRNA-Downregulated-Unnamed_7_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01494
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16694
Brain Lower Grade Glioma_LGG_TCGA-HW-8319-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K02230174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82818
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.953352
metabolic	GAD High Level Gene-Disease Associations	1.0	0.310806
notochord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319134
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15803
PECAPJ41CLONED2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5181
BRD-K69074358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72881
PMC9950457-mmc3.xlsx-GRHL2_overexpression_UP-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cefapirin-7142	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
t64-ovaries_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.53562
SW872	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Diseases	CTD Gene-Disease Associations	1.0	1.09262
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.944387
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91094364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0534
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02035
BRD-K04325154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2177
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02542
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13894
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K03381861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96148
BRD-K02060635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06333
cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.599097
BRD-K50177531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45046
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16694
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58658
BRD-K64132098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31025
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.43097
BRD-K16551475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56218
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11674
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.895809
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02542
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371245
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51535480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07284
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15849
han	GeneRIF Biological Term Annotations	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221755
axon hillock	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.732422
BRD-K81139344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33996
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell-cell adhesion mediated by cadherin	GO Biological Process Annotations 2023	1.0	null
Blepharocheilodontic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.64301
SW1990	DepMap CRISPR Gene Dependency	1.0	2.08162
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49842
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.928906
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7532
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32686
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17191
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25446
KSR2_knockout_60_GSE17923	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.24057
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
NUP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23476
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078087
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35675
MTF2	ChEA Transcription Factor Targets	1.0	null
floor plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405935
BRD-K39159284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14787
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32899
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08192
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.887
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98792
BRD-K21789048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93565
endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.656242
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25546
robust nucleus of arcopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.5672
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30286
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846276
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36021
Prostate adenocarcinoma_PRAD_TCGA-HC-7081-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85044233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33939
chinese	GeneRIF Biological Term Annotations	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65249
Spinal cord_CT1_Dorsal Inhibitory Neuron 5	HuBMAP ASCT+B Annotations	1.0	null
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8047
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.231
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24234
pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239007
19139136-TableS1	GeneSigDB Published Gene Signatures	1.0	null
neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17757
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24133
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992547
riluzole-7365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K02053819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14447
BRD-K64939364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10381
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36454
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAL-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
LN235	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22131
r3 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05957
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02542
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12565
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.975449
mephenesin-7374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
deltaEF1	MotifMap Predicted Transcription Factor Targets	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08723
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03503
BRD-K67229323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11317
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1665
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.849707
BRD-K81510336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35561
SPATS2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38888
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58332
BRD-K97237010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05799
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42571
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24133
LS411N	Achilles Cell Line Gene Essentiality Profiles	1.0	1.87068
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.39531
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02308
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
0175029-0000-7392	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
viomycin-7278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59502
BRD-K60192542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94539
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.57042
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07425
BRD-K64135153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41938
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MELAS - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes_Muscle - Striated (Skeletal) (MMHCC)_GSE1462	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.042
parbendazole-3799	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14231
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.58
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.33434
superficial stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11506
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00934
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45522895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80326
Hippo signaling regulation	WikiPathways Pathways 2024	1.0	null
arcopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13191
Lung squamous cell carcinoma_LUSC_TCGA-85-8664-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58266
BRD-K82933801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51449
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19912
TP53_DEPLETION_GDS4070_451_human_MDA-MB-231 breast cancer cells (depleted of MUTANT-p53)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26307
BRD-K89632963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00213
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34335
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42011
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892222
SOX2	ChEA Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.939447
dicoumarol-4323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17715
Umbilical hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
CAOV4	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05309
BRD-K38111331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53409
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21762
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947966
SUSA	DepMap CRISPR Gene Dependency	1.0	4.25296
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03031
BRD-K82785545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55542
Prostate adenocarcinoma_PRAD_TCGA-EJ-5527-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7321-01A-31R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.843119
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r4 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16658
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15487
BRD-K78809123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15105
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K64646189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73059
BRD-K84143716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10311
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
MAFK_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43306617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99128
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15382
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0456
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01976
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.25525
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92057
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29997
Immunoglobulin heavy-and-light chain	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.862869
inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371245
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96717
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73577
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02542
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56455
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96533
BRD-K49472569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03476
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTNND2	Pathway Commons Protein-Protein Interactions	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
adherens junction organization	GO Biological Process Annotations 2015	1.0	null
U343	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35192
dinoprost-6308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12204
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	3.55363
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117033
pretectal nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832832
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12186
BALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.74673
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07464
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ventral juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31605
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31842
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K53953065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00547
BRD-K87080232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02188
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41774
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.82949
BRD-K19645475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07424
cell-cell junction organization	GO Biological Process Annotations 2015	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02534
BRD-K41709602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13884
FER	Pathway Commons Protein-Protein Interactions	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827085
GPALPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42357
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05273
ERBB2	Pathway Commons Protein-Protein Interactions	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40251180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84472
DIFI	DepMap CRISPR Gene Dependency	1.0	3.89172
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARMCX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23852
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.923784
Prestwick-685-7382	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.36889
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36993
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52926
BRD-K34737616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37324
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21061
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
medial part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18718
Prestwick-642-4594	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
haloperidol-4678	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
wortmannin-4467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2433
EZH2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14004
FAM217B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10304
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24284160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5657
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	1.90158
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48844
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
EPLC272H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37313
isradipine-6347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE133683_1_v_5_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SC-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.11167
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975165
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11801
Prestwick-665-7380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_8-Supplementary_Table_8_ETV6-repressed_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
piperacillin-4320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC4392212-gutjnl-2013-306620-s9.pdf-7-ZNF331_ZNF331	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH889	CCLE Cell Line Gene CNV Profiles	1.0	1.92694
valdecoxib-6408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.20132
BRD-K21450593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24114
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933264
T3M4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32499
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-421_ChIP-Seq_H3K9me1_2_AR_differential_expression_upon_KDM3A_or_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35848
BRD-K50240676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35108
BRD-K24070365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66652
Otosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852508
BRD-K84949119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07852
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1411
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115751
Brain Lower Grade Glioma_LGG_TCGA-E1-5305-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74112
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880441
Catenin binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22835
huh-7	BioGPS Cell Line Gene Expression Profiles	1.0	1.04237
pioglitazone-5977	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anterior pretectal nucleus, ventral core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35883
BRD-K31889353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41429
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96296
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RAD21	ChEA Transcription Factor Targets	1.0	null
FYN	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86906
fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.934911
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.44263
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14914
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
Kallmann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.957277
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12891
BRD-K71420819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41692
BRD-K67022703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27255
BRD-K73114074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34542
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.455284
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.883908
19621087-Table1e	GeneSigDB Published Gene Signatures	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.28672
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13321
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21329
SIRT6	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04601
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTNNB1	Pathway Commons Protein-Protein Interactions	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13536
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960048
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2023	1.0	null
BACH1	ChEA Transcription Factor Targets	1.0	null
ZNF281	ChEA Transcription Factor Targets	1.0	null
BRD-K12097074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29818
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Orofacial cleft 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.846
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0945
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.238755
intermediate stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16658
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K61795707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34261
DiGeorge syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
ankyloblepharon-ectodermal defects-cleft lip/palate syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15047839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.84633
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	1.0	1.94143
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3332
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX4_CDX4	Rummagene Transcription Factor Associations 2026	1.0	null
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3112
TBX5	MotifMap Predicted Transcription Factor Targets	1.0	null
myosmine-4293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05227
BRD-K48188521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15332
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.90134
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K43611837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14638
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.903965
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16889
BRD-K87920761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52895
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31131
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37144
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1574
PMC7738628__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32828
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_state_immune_markers-AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22449045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36955
cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.13978
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.579669
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
single organismal cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
Cell-cell junction organization	Reactome Pathways 2014	1.0	null
SW1417	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32976
BRD-K80877725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90699
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26827
spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.464561
EIF3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55363
CHD2	ENCODE Transcription Factor Targets	1.0	null
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14761
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040692
molecular layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25441
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.933118
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.172544
strophanthidin-5826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31491
GSE77795_2_v_1_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47415214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51277
PMC10645393-jci-133-169200-s102.xlsx-Table_S14_AR-V_DNA-PK_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Adherens junctions interactions	Reactome Pathways 2024	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.0894
BRD-K96023136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3638
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.02119
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10130686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14918
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75563
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
PMC3290552-pone.0032232.s006.xls-MUC4-KD_vs_Mock-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847675
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXC8_HOXC8	Rummagene Transcription Factor Associations 2026	1.0	null
myricetin-4090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
axon part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.085263
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.30556
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventral lateral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4281
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0664
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
rheumatic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
BRD-K96384208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54288
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.386273
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15665
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41972460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27836
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.75398
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66566
BRD-K50830147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13279
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H838	GDSC Cell Line Gene Expression Profiles	-1.0	-1.98973
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.305226
Nephronophthisis 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86754
BRD-K54862370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47505
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217736
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76868
BRD-K87472370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11013
Learning Disorders	CTD Gene-Disease Associations	1.0	1.85573
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62618
CALU-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC85B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01934
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	1.62101
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23757
BRD-K93874059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01861
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56118
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.631123
Lip disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75769
Cadherin conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7470-01A-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33473
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CDK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60087
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
PACADD188	DepMap CRISPR Gene Dependency	1.0	2.9438
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54523
KDM5A	ENCODE Transcription Factor Targets	1.0	null
CMK86	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07753
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SU8686	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54597
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866829
PSS008	DepMap CRISPR Gene Dependency	1.0	5.92911
Field CA3, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75437
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
Lung squamous cell carcinoma_LUSC_TCGA-66-2793-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
valproic acid-1214	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K19536737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08508
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.268237
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69393
HCC56	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32712
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.429465
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.184082
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.258594
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63988
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HARA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3761
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	1.0	1.11718
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K63394284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00325
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
atropine-5865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426109
NCIH522	CCLE Cell Line Gene Expression Profiles	1.0	1.76613
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.36277
melanoma	GeneRIF Biological Term Annotations	1.0	null
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07964
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265038
mantle zone of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32149
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305722
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058044
fulvestrant-5931	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
catenin complex	GO Cellular Component Annotations 2023	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.923922
BRD-K54604127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30577
mantle zone of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39184
Gastroschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
TOP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09193
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autism	DisGeNET Gene-Disease Associations	1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068798
estradiol-4432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STK33_SKM	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02183
CTBP2	ENCODE Transcription Factor Targets	1.0	null
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neostriatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.595255
BRD-K06147970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78616
TE617T	CCLE Cell Line Gene Expression Profiles	1.0	2.50665
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02484
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.069645
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27155
CTNNB1	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K62213484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50684
SNU201	CCLE Cell Line Gene CNV Profiles	1.0	1.50148
Prostate adenocarcinoma_PRAD_TCGA-EJ-5530-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5275-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51478
GRANTA-519	COSMIC Cell Line Gene CNV Profiles	1.0	2.11167
BRD-K92701606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.94437
LRRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40351
Neural Crest Differentiation(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25166
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17886576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29106
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cdh7	GeneRIF Biological Term Annotations	1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99482176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29304
BRD-K41310621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.021
BRD-K05970499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28956
BRD-K80858297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09566
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7349
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63757821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23398
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.429859
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05004
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00565
Ebolavirus(ZEBOV)_1day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.78764
inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.672506
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11386
Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
griseofulvin-7363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
nidopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.67821
BRD-K65733046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22371
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00318
BRD-K87558616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52925
BRD-K04559718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.14778
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80663
interacts	GeneRIF Biological Term Annotations	1.0	null
PMC8421368-41598_2021_97059_MOESM3_ESM.xlsx-Genesets-GSC_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.53989
BRD-K90264208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0048
ATXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19514
Brain Lower Grade Glioma_LGG_TCGA-HT-7485-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UMRC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93662
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75220555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40318
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55627
BRD-K97921950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75701
EWSR1_KD_GDS4962_469_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062943
H4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K97067262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24419
SARS-CoV_12Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.35193
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.026781
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XC-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
used	GeneRIF Biological Term Annotations	1.0	null
BRD-K36909552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30848
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1048	CCLE Cell Line Gene Expression Profiles	-1.0	-1.649
BRD-K86935536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17127
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918754
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.188326
BRD-K97373334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00284
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.544549
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K36465335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98423
KURAMOCHI	Achilles Cell Line Gene Essentiality Profiles	1.0	1.69108
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12868
charge	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3787
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28039
fluphenazine-5880	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12397820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19022
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17198
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.552213
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STOML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92138
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKCO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98948
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03588
PMC9203705-10.1182-2021014723_bloodbld2021014723-suppl2.xlsx-Supp_Table_7-Supplementary_Table_7_Top-list_genes_differentially_expressed_in_CDX2_UBTF_ALL_pvalue_10-7_and_log2_fold_change_3_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K82202634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0438
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
hyperpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.58732
BRD-K45909830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02657
SFRP5_KO_GDS4988_27_mouse_gonadal white adipose tissue HFD	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mantle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.567626
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERBB3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76654183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11847
BRD-K13559806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00834
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDH12	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14245
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.272241
6-bromoindirubin-3'-oxime-6585	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K69175109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62612
Age Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19417
BRD-A30962679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62955
Methionine	CTD Gene-Chemical Interactions	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_12_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Adherens junctions interactions	Reactome Pathways 2014	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6743-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIF1A_01_348	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.93139
BRD-K84457681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96198
BRD-K03221986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39811
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K60454848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46171
GRANTA519	CCLE Cell Line Gene CNV Profiles	1.0	3.2093
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10884
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K57472585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5909
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
nomifensine-5863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K59841546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14972
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.927192
BRD-K63111122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06382
BRD-K69834831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2208
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25801
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70941976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61059
cell adhesion	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11288
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186866
Cell junction organization	Reactome Pathways 2014	1.0	null
BRD-K69093885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65031
BRD-K13551202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0068
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
PMC7176284-pcbi.1007753.s008.xlsx-2_MYCN-NA_NBL_Multimodal_Genes-gene_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
KIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4704
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900003
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
0173570-0000-7391	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11756
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40984
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957217
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
Ammon's horn	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21798
BRD-K97839095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03278
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51719
CP-944629-7502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.32645
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975165
BRD-K92544320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45989
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893861
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043988
BRD-K03546460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22461
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
cell junction assembly	GO Biological Process Annotations 2015	1.0	null
BRD-K11477112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9126
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48148
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042889
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.032094
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.48529
BRD-K63420290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7379
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09897
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03593
superficial stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25266
Neural crest differentiation	WikiPathways Pathways 2024	1.0	null
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03402
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40872
hippocampus (cortex Ammonis)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13706
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14231
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01788
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922349
binding	GO Molecular Function Annotations 2015	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1947
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49261
RGS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21761
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TE6	DepMap CRISPR Gene Dependency	1.0	4.15502
G57321FI	GlyGen Glycosylated Proteins	1.0	null
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56519
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.921532
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
A_CA_04_2009_4dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.39245
BRD-K11577431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31534
K562	BioGPS Cell Line Gene Expression Profiles	1.0	2.41003
BRDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03417
BRD-K02946901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03208
BRD-K57748937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71264
desipramine-6693	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K80782159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64435
HCC1187	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.20988
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CPCN	CCLE Cell Line Gene Expression Profiles	1.0	2.03854
BRD-K45677596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19567
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34161
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12782513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39701
Specific language impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
BRD-K56301498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44146
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87D-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47618355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79129
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2811
neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.463598
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52706
calcium ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K43261169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18619
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866936
BRD-K10325583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49556
Severe acute respiratory syndrome (SARS)_Peripheral blood mononuclear cell_GSE1739	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.5992
BLVRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11142
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52177
acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.192971
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
HT55	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65231
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.015
inhibitory	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAP1	ChEA Transcription Factor Targets	1.0	null
BRD-K75451592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12492
SNU1033	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20584
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.36291
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54075
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.920533
GSE126127_2_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24156533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53604
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.32489
GLI1-17442700-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41556
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38176
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.52242
pioglitazone-7088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93839
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K51272331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27312
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.043273
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10865
Lung adenocarcinoma_LUAD_TCGA-38-4629-01A-02R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.256925
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41854
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01365
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.71789
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.862144
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92141
BRD-K72754669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4859
halcinonide-7379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UMC-11	GDSC Cell Line Gene Expression Profiles	1.0	1.63565
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49726
KP-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22943
GRANTA-519	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14403
SUZ12-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
BRD-K72717797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34206
Blepharocheilodontic syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.118
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.70886
immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
bumetanide-5117	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K56950366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00845
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20071
pioglitazone-6893	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.19759
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	2.32421
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9203705-bloodBLD2021014723-suppl2.xlsx-Supp_Table_7-Supplementary_Table_7_Top-list_genes_differentially_expressed_in_CDX2_UBTF_ALL_pvalue_10-7_and_log2_fold_change_3_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
Cadherin	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K61560971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8806
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97666659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63925
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00717
MAC2A	DepMap CRISPR Gene Dependency	1.0	2.09131
BRD-K78477132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20603
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880793
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59334
BRD-K18084996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01906
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94346
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63748
homophilic cell adhesion via plasma membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.11167
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33156
OAW42	Achilles Cell Line Gene Essentiality Profiles	1.0	1.04993
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91051
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19688
TCF4	ChEA Transcription Factor Targets	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
developmental	GAD High Level Gene-Disease Associations	1.0	0.293278
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06964
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.75672
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25457
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309335
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63748
AZIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04863
BRD-K09275191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05584
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22227
pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278251
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41589
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K71452779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09677
Wolf-Hirschhorn syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
PMC9174176-41467_2022_30924_MOESM6_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
EFO-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01894
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.967349
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.702308
BRD-K15434241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05027
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51694
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K29898553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21605
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922349
Colorectal Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59346
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240636
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.636785
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.886199
LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01572
NCI-H2085	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61901
Ezh2_Deficiency_GDS4309_364_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.722398
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44419
membrane	GO Cellular Component Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49676
carteolol-4096	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
valproic acid-1240	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.953932
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04383
BRD-K11596967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1059
metal ion binding	GO Molecular Function Annotations 2023	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17405
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.8576
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pioglitazone-5930	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.11809
Brain Lower Grade Glioma_LGG_TCGA-FG-8182-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.81708
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.46285
Prestwick-1080-4532	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64278
paroxetine-3821	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
layer 3 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06693
BRD-K57244822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20229
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE126127_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCDHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2613
BRD-K82681356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13847
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70I-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-99-8032-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14231
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40688
tomatidine-5808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7585
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.61963
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08041
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946843
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69723
PCI-6A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8041-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2405	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68671
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23962
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7686
diclofenamide-6686	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K70262646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09175
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955934
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K40300525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28679
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03604
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91138
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.335233
SAP30	ENCODE Transcription Factor Targets	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
BRD-K61354849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45431
BRD-K31977946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21895
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35269
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9174176-41467_2022_30924_MOESM5_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
BRD-K84593579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94903
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53707
PDX1-19855005-MIN6-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51859
DHX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39726
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25856
PANK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01684
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3L7-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
PCGF2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
speech-language disorder-1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
WM88	CCLE Cell Line Gene CNV Profiles	1.0	1.43131
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08259
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
HS729	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55835
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K41141507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1617
BRD-K26395018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5436
Nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_7_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47661
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880441
BRD-K78828094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03391
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pigment dispersion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63748
BRD-K89638177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45263
BRD-K32727528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36506
spinal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289226
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15299
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.508929
RAB3A_KO_GDS2483_701_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Diazinon	CTD Gene-Chemical Interactions	1.0	null
Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3678	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.42395
BRD-K67460571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0668
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26612358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23786
Teebi hypertelorism syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cadherin binding	GO Molecular Function Annotations 2023	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01988
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866829
homatropine-5058	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K47995281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25867
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49842
SK-MEL-3	GDSC Cell Line Gene Expression Profiles	1.0	1.48188
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946843
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.545977
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14457
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86763
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2994
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04243
ethotoin-4545	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Scheuermann's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	1.72589
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K20160406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01059
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00502
phenelzine-4538	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-3.84319
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06645
YKG1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28949
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0266
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.89126
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46043
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47804666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30094
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841328
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86906
TEAD4	ENCODE Transcription Factor Targets	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K65729053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27284
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.57075
BRD-K72709319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37021
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.13312
BRD-K70127757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33481
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.921124
BRD-K76966915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40783
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35915
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04411
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Branchiooculofacial syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12074
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.85018
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302838
BRD-K50961262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38688
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31799
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83898
FADU	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.15836
BRD-K62248885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22081
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3739
Field CA2, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72347
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.68639
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02608
BRD-K88620071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20257
BRD-K77601667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07704
BRD-K60272064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12913
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22485
BRD-K54554531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18781
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.89126
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28802
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76991
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29392
Field CA1, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10687
mephentermine-7384	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
neomycin-5867	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-dORF6_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.73667
DPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29648
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
Wnt signaling pathway	PANTHER Pathways	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89264
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38396
ovary	HPA Tissue Gene Expression Profiles	1.0	0.975631
BRD-K25540102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15394
Unipolar Depression	DisGeNET Gene-Disease Associations	1.0	null
migration	GeneRIF Biological Term Annotations	1.0	null
CP-863187-7558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K75869095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91509
BRD-K56041932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13522
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6097700-pgen.1007515.s007.xlsx-S1_Table-S1_Table_SATB2_NuRD_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22448
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-CoV MA15_Day4-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.65125
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960833
Bone_Marrow-hematopoietic stem cell	Tabula Sapiens Gene-Cell Associations	1.0	1.39025
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
BRD-K14210122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02624
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1112
Sarcoma_SARC_TCGA-QQ-A8VG-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76713927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15306
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H3122	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-8198-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76803075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19393
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13564
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.74673
BRD-K37637965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49076
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23246
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6078
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K76008396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13459
CITED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52947
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871677
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	11.8978
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TERF2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04336
BRD-K65183353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13887
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06463
sulfamethoxazole-7366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Scoliosis, Isolated, Susceptibility To, 3	DisGeNET Gene-Disease Associations	1.0	null
Saethre-Chotzen syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
COR-L95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.97939
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64985
BRD-K17910820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13728
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15350548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1714
PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947131
BRD-K60799989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11462
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14487
BRD-K13225050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20413
0179445-0000-4292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10501
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01427
Cell-Cell communication	Reactome Pathways 2014	1.0	null
BRD-K72800151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4295
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE101537_1_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
BRD-K57937572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9028
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66423
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38826
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Feingold syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894517
anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245175
PCGF2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kyphosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.741516
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.16733
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69076
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38471
NCI-N87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-893	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.689634
BRD-K96295480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42779
Field CA3, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77367
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43452
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836759
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.7332
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Presubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34261
CADOES1	CCLE Cell Line Gene CNV Profiles	1.0	1.9508
ChIP_ZFP281_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08729
systemic scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
meglumine-6685	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
phenformin-3725	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
benfluorex-6727	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nodular ganglioneuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.25619
ERBB4	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17158
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03708
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55714
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02719
BRD-K98510376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44063
SRC	Pathway Commons Protein-Protein Interactions	1.0	null
HT55	Achilles Cell Line Gene Essentiality Profiles	1.0	1.04986
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23175
OVCAR5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71261
Koolen de Vries syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26597
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94881
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848558
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
HEL	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82629
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08659
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.451631
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45504
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05435
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67688
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
SW1116	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39647
BRD-K37656403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52328
Spinal cord_CT1_Dorsal Inhibitory Neuron 5	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.783141
EIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3972
NCI-H1963	COSMIC Cell Line Gene CNV Profiles	1.0	2.11167
BRD-K11726285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1334
BRD-K67082570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28187
flufenamic acid-5059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888424
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.35779
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
BRD-K75649446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05336
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disorder	GeneRIF Biological Term Annotations	1.0	null
BRD-K11873306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60037
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01339
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5495-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebrooculofacioskeletal syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
BRD-K36031198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1681
BRD-K78222058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0187
LK2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01361
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nezelof syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0341
adherens junction organization	GO Biological Process Annotations 2023	1.0	null
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31842
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84481
VAL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
raphe nuclei of medulla	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.966893
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pleural mesothelioma	WikiPathways Pathways 2024	1.0	null
PFSK1	DepMap CRISPR Gene Dependency	1.0	10.3015
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55206
BRD-K29549246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38402
monensin-7402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87071
BRD-K91588908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13121
NELFCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32214
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.74174
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.67495
optic lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.968955
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61855
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.679025
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09468
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064626
BRD-K86050213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56026
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.397979
buspirone-6743	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849828
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
sulfadimethoxine-7400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cadherin signaling pathway	PANTHER Pathways	1.0	null
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11528
BRD-K02329600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15701
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41521
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10575
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872892
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89809
Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEN	GDSC Cell Line Gene Expression Profiles	1.0	1.80453
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.73062
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
foliosidine-4295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053589
alexidine-7397	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
solasodine-3749	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EVX2_EVX2	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22009
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.12617
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRA_RXRA	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07725
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
laterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30341
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K84401063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26228
tolbutamide-4540	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K61168922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47536
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
alvespimycin-4437	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DMS273	CCLE Cell Line Gene Expression Profiles	1.0	1.43709
DETROIT562	CCLE Cell Line Gene Expression Profiles	-1.0	-1.558
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K64347765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19306
GSTZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22583
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ANXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45466
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	2.13003
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IST-SL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880441
BRD-K14268329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84838
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869895
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33789
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09254
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07217
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14787
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02199
ethisterone-3783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Adolescent Idiopathic Scoliosis	DisGeNET Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7232-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15289
MYC	ENCODE Transcription Factor Targets	1.0	null
SHP-77	GDSC Cell Line Gene Expression Profiles	1.0	1.50062
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
support	GeneRIF Biological Term Annotations	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
BRD-K16109630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03956
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3222
BRD-K24984327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25258
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30122
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.519253
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2963
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82074
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83547183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73191
RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.921532
NCIH2171	CCLE Cell Line Gene Expression Profiles	1.0	1.8502
outer SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928103
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.51964
BRD-K58743752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39428
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10474
TBP	ENCODE Transcription Factor Targets	1.0	null
JP-4-043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46656
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352227
Ectodermal dysplasia 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.086
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL95	CCLE Cell Line Gene CNV Profiles	1.0	1.62652
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07861
leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053526
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12665145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01659
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
lymph node	HPA Tissue Protein Expression Profiles	1.0	0.873624
mammary paget's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.655254
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830892
bambuterol-5885	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067051
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.931912
single organism cell adhesion	GO Biological Process Annotations 2015	1.0	null
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32434
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.642048
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30401
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.56799
BRD-K81200901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0402
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
FAM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16084
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88263
BRD-K64665523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17078
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.933118
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02116
BRD-K16064200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80244
BRD-K05475322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48868
rhombomere 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00107
NLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14187
BRD-K92365616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23433
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56071
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15056
BRD-K76900919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64795
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63171
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45449
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.429465
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03193
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65241
BRD-K84636055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36112
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.827195
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39567
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JW-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.478038
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4896
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.1658
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53493
3-acetamidocoumarin-4601	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15896
CYYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26353
alexidine-3699	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
BRD-K62017257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25143
Hypogonadotropic hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
ISTMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.68609
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989586
BRD-K53774864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19629
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYM1	CCLE Cell Line Gene Expression Profiles	1.0	1.69034
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
melanoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.571219
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974713
GLI1	ChEA Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04809
BRD-K62085719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01647
BRD-K28467941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47896
Field CA3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69208
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.979194
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.89785
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5516-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86285108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03153
BRD-K26636241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8691
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74465
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA2_156_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12181036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36614
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77776
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41362
BRD-K35646839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02094
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
BRD-K99131664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36245
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36075
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02167
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960325
BRD-K81450614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1786
intermediate stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52442
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.899338
Brain Lower Grade Glioma_LGG_TCGA-DB-5277-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65302
ZFP281-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880727
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.39135
TGFBR2_knockout_295_GSE45968	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.65627
BRD-K48143921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26681
NCIH747	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54983
ecad	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHARGE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.655
AGO2_02_132	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.32193
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13624
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918754
Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53617314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61889
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00311
BRD-K53548223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26363
Field CA3, stratum lucidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86763
Dentate gyrus, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35639
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.867296
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZFAND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31598
bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308612
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
PPARD	ChEA Transcription Factor Targets	1.0	null
PMC10042887-41419_2023_5742_MOESM4_ESM.xlsx-Table_S4-Table_S4_Overlap_genes_of_HOXB3_vs_HOXB3-_and_APC-KO_vs_APC-intact_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
metaraminol-3669	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LEDGF_KD_GDS1580_249_human_293T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.604904
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60449
GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r4 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6051
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946843
BRD-K68119260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1177
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.7321
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03867
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K02866760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30967
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00913
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08587
hesperidin-6714	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
icSARS-Cov_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.2541
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
marker	GeneRIF Biological Term Annotations	1.0	null
Depressive Disorder, Major	HuGE Navigator Gene-Phenotype Associations	1.0	null
mesenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510206
PCI-4B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.20295
risk	GeneRIF Biological Term Annotations	1.0	null
TT	GDSC Cell Line Gene Expression Profiles	1.0	1.86762
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APLP2_KO_GDS4414_536_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09937
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.55601
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08845
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982058
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.26131
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
layer 2 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01865
craniofacial-deafness-hand syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.752
BRD-K74754874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23681
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12533
ChIP_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K51207618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40341
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63645
PLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07582
r4 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6851
BRD-K73795883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12836
PLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38201
Sarcoma_SARC_TCGA-KD-A5QT-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K17482709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32967
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864034
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15418
tinidazole-4548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74916896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0032
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.07483
nerve	GTEx Tissue Gene Expression Profiles	1.0	2.08869
intermediate stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31444
Inflammation	CTD Gene-Disease Associations	1.0	1.12219
BRD-K45694673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14231
Cadherin, cytoplasmic domain	InterPro Predicted Protein Domain Annotations	1.0	null
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11763
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
adherens junction	GO Cellular Component Annotations 2023	1.0	null
superficial gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13166
PMC9203705-10.1182-2021014723_bloodbld2021014723-suppl2.xlsx-Supp_Table_5-Supplementary_Table_5_List_of_genes_identified_by_WGCNA_corresponding_to_the_CDX2_UBTF_cluster_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU-134-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
BRD-K23405293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96624
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2921
SUZ12	ChEA Transcription Factor Targets	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62227
SNUC5	DepMap CRISPR Gene Dependency	1.0	2.96611
TTC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9402
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85622666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79099
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00607
sulfamonomethoxine-5843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dilazep-7364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adenomatous Polyposis Coli	DisGeNET Gene-Disease Associations	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30943
superficial stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31138
COLO668	CCLE Cell Line Gene Expression Profiles	1.0	1.57453
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66413
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0861
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.545342
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.91074
sulfadimethoxine-3702	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39567
Prestwick-674-4276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88902
LS123	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35881
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.09226
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
naphazoline-6604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0263
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5507
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K51411441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62156
fluticasone-4011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23106
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991808
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44353
PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_1W_vs_LS_1W-gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04503
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17865
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946843
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16131
H3K9me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVCAR4	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01705
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.95784
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87241
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K48408404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24878
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22376
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11861
ZFP281-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung sarcomatoid carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.607
15-delta prostaglandin J2-4455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K80196706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42817
BRD-K74311661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82942
cerebellar mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.02779
0173570-0000-7389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kabuki syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
BRD-K96615474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20556
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.919198
BRD-K52414345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07457
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54895
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU8686	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81701
embryonic brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358919
BRD-K57830670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03522
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8411-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39227064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31924
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXA13_HOXA13	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SIX1_SIX1	Rummagene Transcription Factor Associations 2026	1.0	null
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12302
FOXO1_KD_GDS2720_477_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.818158
proglumide-3780	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0538
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.957705
HDAC2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26024910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92182
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
MV411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.76345
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55835
D425	DepMap CRISPR Gene Dependency	1.0	2.12195
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887971
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00743
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352598
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.172291
BRD-K48053776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01333
intermediate stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35653
REST	ChEA Transcription Factor Targets	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.915038
CTCF	ENCODE Transcription Factor Targets	1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	3.44617
etynodiol-6678	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nitrofurantoin-7373	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K23051691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21457
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60454
BRD-K96925976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20815
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973858
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64531971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75249
BRD-K33454318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44943
BRD-K73296174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53259
KNS81	DepMap CRISPR Gene Dependency	1.0	3.04879
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.706156
PF-00875133-00-5928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LS-411N	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47664
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.01999
CAS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75637
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30994
lycorine-3808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15368
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881857
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340019
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10303
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_5_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62229896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43525
PMC8312441__F7	PFOCR Pathway Figure Associations 2024	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33789
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05594
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
lateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21029
axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.287352
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06056
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.22254
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157218
NCI-H2171	GDSC Cell Line Gene Expression Profiles	1.0	1.43372
BRD-K98117883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31949
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17426248-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45422
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39902
BRD-K68635551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30105
CDH15	Pathway Commons Protein-Protein Interactions	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.40815
BRD-K39013648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4493
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24318
PPAR-26484153-CHIP-SEQ-NCI-H1993-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09498
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.429165
NCIH661	CCLE Cell Line Gene Expression Profiles	1.0	1.80215
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40083
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61777
BRD-K32485819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24516
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01717
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02224
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
GT3TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	3.40782
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890282
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48141
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.946517
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79735667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24904
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21235
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81S-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
syndrome	GeneRIF Biological Term Annotations	1.0	null
BRD-K85456301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44997
GSE149903_3_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21093
BRD-K78162975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04439
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital hypotrichosis with juvenile macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
BRD-K49704392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91963
sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.283655
NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K97330035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95788
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Cadherin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6978-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27028848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18805
Mandibulofacial dysostosis with alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45176
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	5.36779
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416576
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92759025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06245
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30943
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.950876
Prestwick-864-3994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDH6	Pathway Commons Protein-Protein Interactions	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10758
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.736
Transient tic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
C33A	DepMap CRISPR Gene Dependency	1.0	8.58867
cell-cell junction organization	GO Biological Process Annotations 2023	1.0	null
avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.74834
SNU899	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79964
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-0.778088
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2778
BRD-K82909038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21122
BRD-K15157905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54524
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.52731
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_9_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K57502201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22481
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_upregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Tegmental reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24311
NIX_Deficiency_GDS2630_655_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K90801819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02295
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56779
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46739
cell-cell junction	GO Cellular Component Annotations 2023	1.0	null
BRD-K75625428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48858
BIRC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08755
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866829
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.821502
NIX_Deficiency_GDS2630_160_mouse_spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.44187
efficient	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17562
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40624
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07797
BRD-K11003742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50441
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19901
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16251
HCC2814	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22736
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46249
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.720345
BRD-K65107903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08805
Brain Lower Grade Glioma_LGG_TCGA-DU-7008-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS940-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K09017160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19961
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.17333
prostate	HPA Tissue Gene Expression Profiles	1.0	1.259
PMC12728157-mmc5.pdf-2-EBF1_1_1_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97484
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K57155690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26643
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
MNX1-26342078-MIN6-4N-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K27058632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38123
Chromosome 18p deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
BRD-K75539052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04167
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13482
BRD-K14567490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52401
Hirschsprung's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
PMC11799605-jomes-34-1-65-supple.pdf-11-KLF16_KLF16	Rummagene Transcription Factor Associations 2026	1.0	null
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	0.883099
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.35569
BRD-K03765511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53232
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05594
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6-bromoindirubin-3'-oxime-7106	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH460	CCLE Cell Line Gene Expression Profiles	1.0	1.36925
NCI-H661	GDSC Cell Line Gene Expression Profiles	1.0	3.0569
FOXA2	ENCODE Transcription Factor Targets	1.0	null
subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.9889
NCIH358	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18586
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21587
SKRC20	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.14723
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.234174
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.56226
BRD-K65266979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2408
5194442-6553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K58735963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18915
motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.631123
BRD-K99847716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13158
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.411039
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067122
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
lovastatin-6633	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH2452	Achilles Cell Line Gene Essentiality Profiles	1.0	1.50023
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.41771
BRD-K28305165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45325
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bucladesine-5886	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.719298
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070305
E2F6	ENCODE Transcription Factor Targets	1.0	null
BRD-K75007044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09209
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932053
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56322
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
brain	HPA Tissue Gene Expression Profiles	1.0	1.79567
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6401-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54278
BRD-K67626097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19807
SW13	GDSC Cell Line Gene Expression Profiles	1.0	2.30025
BRD-K74987024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15847
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27425
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
catenin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.462398
PMC7738628__F6	PFOCR Pathway Figure Associations 2023	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891193
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.9972
BRD-K68853384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06022
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14815
Brain Lower Grade Glioma_LGG_TCGA-DU-7019-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15-delta prostaglandin J2-1231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35332
PNU-0230031-3732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09025
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14231
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44331
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16033
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178011
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54943
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06619
HDAC2	ENCODE Transcription Factor Targets	1.0	null
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05433
Lung squamous cell carcinoma_LUSC_TCGA-60-2725-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Elsahy-Waters syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
mebendazole-7370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263327
BRD-K28195874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75057
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047585
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02083
review	GeneRIF Biological Term Annotations	1.0	null
ES8	DepMap CRISPR Gene Dependency	1.0	2.00006
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.72322
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.43591
WDR83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26864
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240636
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32493
BRD-K10459843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50346
cation binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K00137579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78426
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828736
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.310652
PAX3	ChEA Transcription Factor Targets	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45394
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K18623962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27195
BRD-K89260735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40085
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.26722
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412771
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_3_AP1_Up_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
DU4475	DepMap CRISPR Gene Dependency	1.0	3.14427
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.931677
ETV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11194
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.898341
ion binding	GO Molecular Function Annotations 2015	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.65937
BRD-A52377240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52046
icSARA deltaORF6_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.7684
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
clotrimazole-5726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
azaperone-5877	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31914
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21992
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.891945
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31232
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7611-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065468
LU-135	GDSC Cell Line Gene Expression Profiles	1.0	1.84178
HAUS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87045
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.239916
NCI-H1092	GDSC Cell Line Gene Expression Profiles	1.0	1.79807
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01124
BRD-K73969016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16971
LEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92088
Triglycerides	dbGAP Gene-Trait Associations	1.0	0.238602
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.953268
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52449
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.358749
Prostate adenocarcinoma_PRAD_TCGA-HC-8257-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
troglitazone-1232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K05090634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70029
XPodNet - protein-protein interactions in the podocyte expanded by STRING(Mus musculus)	WikiPathways Pathways 2014	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5744-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66646
18955564-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922349
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880441
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	1.47242
BRD-K73874262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03131
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069374
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.27077
hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2779
SUZ12	ENCODE Transcription Factor Targets	1.0	null
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17562
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.930011
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68469
Cell-Cell communication	Reactome Pathways 2024	1.0	null
BRD-K91180296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37855
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.215063
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.535686
BRD-K22071228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0232
BRD-A61014366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18002
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14736
SHP77	CCLE Cell Line Gene Expression Profiles	1.0	1.53787
VCAP	CCLE Cell Line Gene Expression Profiles	1.0	2.25084
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70226
hycanthone-4630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.08655
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89216747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34631
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04766
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.02644
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sirt1_OE_GDS2658_140_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891817
clebopride-6311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ataxia	CTD Gene-Disease Associations	1.0	1.10104
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880441
BRD-K46913557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37244
cellular component organization	GO Biological Process Annotations 2015	1.0	null
HT144	DepMap CRISPR Gene Dependency	1.0	2.398
RUNX2	ChEA Transcription Factor Targets	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	0.873624
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.692964
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.12223
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05594
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63375777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52347
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K09972656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46366
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841328
BRD-K09732051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35308
BRD-K83667863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53649
NCI-H322M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03018
BRD-K36941678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10443
NCIH446	CCLE Cell Line Gene Expression Profiles	1.0	1.50168
Memory Disorders	CTD Gene-Disease Associations	1.0	1.31387
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26224
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16694
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15464
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881119
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.881836
cell part	GO Cellular Component Annotations 2015	1.0	null
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_10_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Pigmented villonodular synovitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K14436020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22017
BRD-K99859971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06862
CSNK2A1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HH-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.86599
BRD-K41999717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34084
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.228
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63748
BRD-K20714346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29096
RERF-LC-MS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2985
BRD-K54386075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55385
Cleft lip	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06349
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K27331198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10275
BRD-K15647573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3217
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.15836
GSE165682_4_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68683482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86962
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.05423
MXI1	ENCODE Transcription Factor Targets	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21745
LOUNH91	DepMap CRISPR Gene Dependency	1.0	3.39041
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926079
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16492
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
Cmah_KO_GDS4770_421_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6470-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.85772
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08036
betahistine-6611	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849745
calcium ion binding	GO Molecular Function Annotations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LTBR_INHIBITION - 3 Days_GDS2005_730_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Field CA1, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33051
IMR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K43918582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9495
rosiglitazone-4457	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K11242872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0678
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31862
LY-294002-4463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59218
FGFR3_knockdown_34_GDS4454	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.94851
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21911
Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-N1-A6IA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21124
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35146
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K64091938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17252
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.451
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42243
H3K27me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7209-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86824
breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.516879
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11209
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.74174
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.840349
BRD-K67194214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69108
colon	HPA Tissue Protein Expression Profiles	1.0	1.11718
GSE120595_0_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86906
hypersensitivity reaction type ii disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
Field CA2, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34266
cell junction organization	GO Biological Process Annotations 2015	1.0	null
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69740275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9922
BRD-K60758969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08044
BRD-K58028568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02593
Pleomorphic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922349
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2023	1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.981006
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922349
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221755
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1648	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49128
PTK7_KD_GSE50138_675_human_H2009	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Choline	CTD Gene-Chemical Interactions	1.0	null
lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27497
BALL-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.11167
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
Calcium	HMDB Metabolites of Enzymes	1.0	null
GSE199541_2_v_5_mbd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01787291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97582
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.21374
population	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83125173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07995
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937165
LOVO	Achilles Cell Line Gene Essentiality Profiles	1.0	3.19156
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.246046
amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.654212
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-2.81605
BRD-K60905390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03525
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067493
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5243-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09937
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	5.24383
BRD-K67740871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13868
MAFK	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05782
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39224209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16755
atractyloside-7393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61503
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AU565	COSMIC Cell Line Gene Mutation Profiles	1.0	null
prednisolone-5101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E2-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9203705-bloodBLD2021014723-suppl2.xlsx-Supp_Table_5-Supplementary_Table_5_List_of_genes_identified_by_WGCNA_corresponding_to_the_CDX2_UBTF_cluster_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29842194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00239
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
BRD-K35517098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19937
ncad	GeneRIF Biological Term Annotations	1.0	null
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FGFR3_knockdown_174_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.81941
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.247
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10239
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97382
Brain Lower Grade Glioma_LGG_TCGA-HT-7483-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69698801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41999
melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.424014
BRD-K05335635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02264
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17332
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
MAFK_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995957
PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-84-ZNF442_ZNF442	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.05873
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02194
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89059
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
19808871-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0305
BRD-K39176069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32553
NUDT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02179
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04581
17426248-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09948
NCIH69	CCLE Cell Line Gene Expression Profiles	1.0	1.68851
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20665
body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294223
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CSNK2B	Pathway Commons Protein-Protein Interactions	1.0	null
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59556
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22227
BRD-K22983069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.027
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866422
karakoline-4297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.89397
SOX11	ChEA Transcription Factor Targets	1.0	null
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387404
dinoprostone-6586	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29917
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39591
MYOC_OE_GDS1640_269_mouse_retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
IGR39	DepMap CRISPR Gene Dependency	1.0	2.62682
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975165
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.27698
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	1.0	1.71837
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5280-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74242
Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A06578049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07939
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69346
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV504	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82995
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36777
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70D-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11391
COLO-741	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7873-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35587518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03298
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.238755
SNU-398	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.760328
skin	HPA Tissue Protein Expression Profiles	-1.0	-1.13793
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
lanatoside C-3771	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chd7	GeneRIF Biological Term Annotations	1.0	null
thiamine_rattus norvegicus_gpl2896_gse19292	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K15236933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59197
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-2_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157218
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.711
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45685
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68433511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26638
quinethazone-4529	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880441
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85861
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K71538933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76907
BRD-K22069962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32043
negatively	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16527
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40136
Cell-cell junction organization	Reactome Pathways 2024	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K23240772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31477
HCC1143	DepMap CRISPR Gene Dependency	1.0	14.7454
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.08896
BRD-K56032186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22163
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33213
NKX1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19385
NCIH1963	CCLE Cell Line Gene CNV Profiles	1.0	2.19193
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950655
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.026364
BRD-K75263760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51976
COR-L303	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.108277
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17035
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OCIMY7	CCLE Cell Line Gene CNV Profiles	1.0	1.35536
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ML-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05204
BRD-K97537859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13557
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6396
BRD-K28982281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68855
BRD-K25016708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1178
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Van der Woude syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
BRD-K00048792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46716
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922349
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16069
BRD-K69491845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03395
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPC-N	GDSC Cell Line Gene Expression Profiles	1.0	2.04954
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U178	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.29491
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1196
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33491
BRD-K77032979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26465
BRD-K94196749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01787
mimosine-6703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04729
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K37254228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53889
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1534
Alternating esotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16985
cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06493
5155877-6544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6192
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49107
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07273
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99447506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26634
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.06112
XPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32141
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897093
BRD-K80880605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11519
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873369
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07434
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894223
BRD-K06507315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0093
oxytetracycline-5772	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83806
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K93747042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45213
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.54042
OCIMY5	DepMap CRISPR Gene Dependency	1.0	3.55038
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02722
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19591
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.456909
NOTCH_INHIBITION_GDS2794_61_human_MOLT4 (T-cell acute lymphoblast leukemia) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868968
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08417
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
depressive	GeneRIF Biological Term Annotations	1.0	null
PDX1	ChEA Transcription Factor Targets	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
Atrophy	CTD Gene-Disease Associations	1.0	1.08868
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K83949633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03966
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947113
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14694
NCI 460	BioGPS Cell Line Gene Expression Profiles	1.0	1.39093
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00381
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04163
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.593649
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13038935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95062
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.975349
Hippo Merlin signaling dysregulation	WikiPathways Pathways 2024	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04476
p3 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1374
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43479
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
TRIM28	ENCODE Transcription Factor Targets	1.0	null
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88057
BRD-K62795540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32637
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.25438
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0621
hypersensitivity reaction disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN3	DepMap CRISPR Gene Dependency	1.0	3.57975
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K92949288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99744
BRD-K78493876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07368
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55475
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.60893
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00502
FGF21	Pathway Commons Protein-Protein Interactions	1.0	null
BRG1_DEPLETION_GDS2156_720_mouse_Embryos (maternally depleted)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974713
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3-nitropropionic acid-6407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21427
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1897	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31971
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40465
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23151
PMC12700546-jci-135-197583-s034.xlsx-ST18-Unnamed_2_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.683974
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1359	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34129
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
Barrett Esophagus_Esophageal Tissue_GSE1420	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.81044
BRD-K33770771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08647
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975165
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928209
Idiopathic scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
phenformin-4283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K01152687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46879
BRD-K97741413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84922
NFE2-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Megacolon	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39185798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14455
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94047
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7697
modulates	GeneRIF Biological Term Annotations	1.0	null
BRD-K38273665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62416
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37047
OCILY3	CCLE Cell Line Gene CNV Profiles	1.0	1.76405
BRD-K96280720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01985
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.346668
TUBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04856
ChIP_GLI1_17442700	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.40815
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13788250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30413
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853938
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150517
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37171
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45586
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5626
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070766
SALE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10491
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null