association	dataset	threshold value	standardized value
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6849
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3859
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.79307
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58503
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66948
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6763
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.517
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7653
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26399
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4661
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6564
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.8125
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5065
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74037
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3461
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0435
SAP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91125
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6423
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44291
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.763
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1005
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9188
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7826
496100513_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75845
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9461
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	221.105
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3944
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1233
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.691
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.195
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86424
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1724
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.32
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.4134
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88087
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9172
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2275
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4047
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.062
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1528
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8041
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6375
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
496100383_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48104
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	5.05159
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2947
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.70041
GSE182680,GSE182683_0_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2387
496100659_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14164
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3597
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2015
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9011
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1856
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.489
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.947
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7367
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.4342
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05034
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1342
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8391
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2566
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3505
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4681
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37855
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4402
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1334
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2563
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.22719
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1476
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.2262
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5689
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3728
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9079
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4988
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03184
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0337
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19889
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8109
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9485
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4064
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1464
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0223
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4226
TLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76489
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.5089
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8165
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1596
QKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83771
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9809
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15227
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19408
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.7628
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	5.05159
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7043
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2069
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0039
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4159
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null