association	dataset	threshold value	standardized value
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.650041
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K02921955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78431
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06425
5738_NOL9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.503673
TTLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04373
Amyotrophic lateral sclerosis type 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
BRD-K60701773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06994
GSE165307_3_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KIF21B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00510914
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548532
Auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.434
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
Edwards syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02301426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43278
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
R2TP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.752
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44685
BRD-K86942117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05975
HELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27967
BRD-K35133923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1587
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53292
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4492
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACVR1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602716
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.672
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29215
NCIH2291_LUNG	CCLE Cell Line Proteomics	1.0	4.18023
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZDHHC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01024
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00038
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-B_FUS-DDIT3-eGFP_vs_WT-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5046
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47988839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21198
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cilium assembly	GO Biological Process Annotations 2023	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17852428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51693
BRD-K30220159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25398
CRCGN015_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0654
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
GF-32-FY02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304297
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49584388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23641
7671_SBNO2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.689231
BRD-K60053695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49029
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tadpole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.37
PYCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496921
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
GSE157296,GSE157298_4_v_2_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69437108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06213
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K00882360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11757
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D2REFED4h_641_AR-D-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A46950333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45578
H2BC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12098
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30236306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93687
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K02634083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40648
BRD-K57969360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62184
CD-10-LX95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340957
BRD-K03512847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13999
GSE205540_2_v_3_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Urophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16472
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24930745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76886
S0-EE-Y79N_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23015
BRD-K05479183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43751
BRD-K02827191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19108
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212503
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
7454_RPL27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.667855
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
cyclothiazide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51413
BRD-K01334037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63312
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hypoplastic left heart syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79716
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COASY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00244971
GSE200352_4_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Corneal Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
BRD-K51163606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16979
BRD-K44779507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05001
BRD-K78741913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37689
6219_PES1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.566125
GSE163282_12_v_2_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.622
CD3G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585243
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.003
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
7466_RPL36_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.524658
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
BRD-K07812227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05166
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.172
GSE232631_5_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60044070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9301
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36763492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18636
GSE152432_9_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5259
BRD-K20053005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29329
CRCGN016_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40757
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
PMC10260402-41588_2023_1399_MOESM4_ESM.xlsx-G_STAT3_x_T21_RNAseq_HSA21-Gene_name_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15373812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52748
BRD-K08527280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69417
BRD-K83934572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64175
BRD-K20284960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27299
CSNK1G2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00427051
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0331
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7149
Sternal cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
e3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00985
BRD-K26127374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39993
BRD-A48478073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60025
X-linked intellectual disability-short stature-overweight syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.32991
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03393
CRCGN012_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23758
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Developmental and epileptic encephalopathy 53	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.324
Spinal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
BRD-K05699155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06823
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
AF-19-KN63_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210173
BRD-K73840377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36811
GSE158834_11_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Newborn respiratory distress syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211142
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K81881801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81293
BRD-K61072684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45684
GSE133683_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
7463_RPL35_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.621215
2226_DIMT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.567976
BRD-K03070790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22115
HUPT4_PANCREAS	CCLE Cell Line Proteomics	1.0	4.53363
1065_CFAP298_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-1.0446
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.521293
BRD-K85821470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15347
BRD-K92826631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60181
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9987
BRD-K74680333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15785
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory Insufficiency Due To Defective Ciliary Clearance	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K18865369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99869
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NEK10	Kinase Library Tyrosine Kinome Atlas	1.0	95.42
betamethasone-valerate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27153
Scheuermann's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
organelle assembly	GO Biological Process Annotations 2025	1.0	null
Chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.302
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1053
BRD-K44956383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11004
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180641_0_v_1_zfp503_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12260418-pnas.2425984122.sd01.xlsx-TEAD4_6fraction_test_result-Unnamed_3_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Kartagener Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7957
BRD-K86453556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51162
GSE118490_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83312314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33581
GLYAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00398483
Orofaciodigital syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
BRD-K99681648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15647
BRD-K84761515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.297
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-pc-S-EC2_Compare_erectile_dysfunction_ECs_vs_normal_ECs_using_either_combined_ED_ED_DM_and_ED_nDM_or_ED_DM_and_ED_nDM_seperately_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CD-12-NI84_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383399
BRD-K56691168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05932
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455098
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39786
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
BRD-K68758594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30003
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0639
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.65567
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K24109044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22063
GSE158834_11_v_5_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GIMAP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054817
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2538
BRD-K55836749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82271
GSE148252_5_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K54925224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.032
9443_TWISTNB_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.530856
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91684468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01279
Clonidine (hydrochloride)_NCI-H2030	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0191535
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.22716
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02122
Respiratory Distress	DisGeNET Gene-Phenotype Associations	1.0	null
H1-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16717
jf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379427
NCIH2286_LUNG	CCLE Cell Line Proteomics	1.0	4.34847
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41915
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1499
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K01991250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90352
BRD-K87541124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10655
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65824451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23983
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.772
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CILP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583638
BRD-K64376499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99856
Radial spoke stalk	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
BRD-K51054234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14249
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
S1PR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00457062
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EPPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1038
Cytostome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
7471_RPL39_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.561827
BRD-K86630280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62824
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03249
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.558
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
BRD-K12909905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13588
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K70791360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30556
7508_RPS19BP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.518097
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5447
BRD-K60437668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11545
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115395_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54111001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54566
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.548
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1594
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
7526_RPS4X_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.50854
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1772
Tracheal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
Collagen beaded filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6569
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Unnamed_5_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Headache	DisGeNET Gene-Phenotype Associations	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.1272
BRD-K31093279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09454
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9305
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10276373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25172
BRD-K79885457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19923
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.758
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4308
BRD-K14193598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89525
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.123
Oral apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7283
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20398
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62265
CRCGN015_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.424
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K59095205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45854
BRD-K06743908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81937
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30581008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22392
BA-52-FW03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246245
7499_RPS11_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.509663
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74936
HEC251_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	4.81777
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of cilium movement	GO Biological Process Annotations 2023	1.0	null
BRD-K09160804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36089
BRD-K36347292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42046
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cilium assembly	GO Biological Process Annotations 2025	1.0	null
BRD-K10027041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81279
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.6299
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100636_FWM_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1795
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85843964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06067
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625615
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.14915
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1252
PBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.204
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.63
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
PMC3076323-pone.0018064.s016.xls-MYCN_targets_Marson_GSE6007-Unnamed_1_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Spontaneous Abortion	DisGeNET Gene-Phenotype Associations	1.0	null
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC4909989-ncomms11840-s3.xlsx-Sheet1-The_overlapped_genes_regulated_by_YAP_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65633211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08925
GSE203308_6_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr21_32683611_T_C_b38	GTEx eQTL 2025	1.0	1.82524
BRD-K40776502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06251
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
Obstructive hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
PMC6412103-mmc1.docx-5-M00695_ETF_P_8_350E-5_N_428_31_5_TEAD2	Rummagene Transcription Factor Associations 2026	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.927
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
BRD-K80546581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52801
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.104
Otitis Media With Effusion	DisGeNET Gene-Disease Associations	1.0	null
BRD-K82683018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09864
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32708
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGR1_SKIN	CCLE Cell Line Proteomics	1.0	9.14476
BRD-K68041793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7187
GSE181521_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K14702616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12405
BRD-K54370483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45976
GSE204784,GSE204787_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.867
BRD-K32879108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26664
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205129
2988_FBL_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.583758
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02798
BRD-K30053194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3431
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89382
BRD-K27294633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33477
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26489
BRD-K21996189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12243
BRD-K06308228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28339
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.0141
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42633
MRPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1488
BRD-K80176886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08884
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49328983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3222
BRD-K98891210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46277
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE101748_0_v_1_apela_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83109105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3287
BRD-A09975616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.145
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40505
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09524
BRD-K48012250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26529
ZNF696	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71104
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0346
GSE183335,GSE183351_3_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6781
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.467
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
6118_PCED1A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.555956
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dynein axonemal particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.792
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
PMC10624900-41467_2023_42825_MOESM13_ESM.xlsx-Module_3-ZNF195_ZNF195	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K13085116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02532
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62888534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37401
BRD-K58843485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41076
GSE198971_0_v_2_ncor2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40765512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05832
Epithalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
BRD-K71755682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72216
BRD-K69443135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00238
plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2025	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8991
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.198
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10087503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02596
CRCGN010_HEPG2_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29662
7511_RPS21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.612614
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9314667-Table_1.xlsx-Regulons-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.45365
TA-20-FO62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244505
PMC9396374-Table_4.XLSX-AR_related_genes_from_OMIM-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79635719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42349
BRD-K20196153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83891
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3596
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K66453893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06312
GSE210476_2_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372921
Conductive Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Recurrent Otitis Media	DisGeNET Gene-Disease Associations	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257577
RARG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00676502
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15952
Common cold	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01452
BRD-K09117810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67327
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.711
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05041765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98549
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97170716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30784
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69109808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18032
GSE241875_1_v_0_huwe1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.13197
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252888
BRD-K79954583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07482
BRD-K86773205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11496
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.542
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1056
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
BRD-K56004278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08241
plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2023	1.0	null
Middle ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.814
BRD-K18599462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74856
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
4270_KANSL1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.501234
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02335
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41909
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9645
BRD-K78676275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30916
SMAD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00438503
GSE128333_2_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.64109
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150072,GSE169209_6_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0007
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5658
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K92399035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36437
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K89471250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08449
BRD-K69543414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15133
CRCGN014_HEPG2_3H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0149
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26796
mIMCD-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5422
BRD-K06261202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85835
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.741
retromer, cargo-selective complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.95
BRD-K09689420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16106
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.084
10478_ZNF585A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.677891
STAT5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600999
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7686
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588651
SIPA1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00553231
cilium organization	GO Biological Process Annotations 2025	1.0	null
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
2124_DDX47_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.527189
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270127
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.807354
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6836
PMC9314667-Table_1.xlsx-Regulons-ELF1_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29707
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42314
BRD-K84387578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1562
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87413
Posterior nuclear complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
2376_DROSHA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.533646
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.18134
BRD-K07836769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39283
OXSR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0068512
BRD-K47690679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16103
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.572111
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88156935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65787
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46683
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
XA-82-BM12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206071
BRD-K20435953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26673
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84792324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29842
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K08995282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82781
CRCGN017_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1732
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K19429335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22353
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22797
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15458
Somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217776,GSE217829_2_v_0_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNNI3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591538
BRD-K79684522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0607
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09099
BRD-K80298486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99899
BRD-K37386363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43473
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3823
BLK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0072009
496100553_TCx_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53076
BRD-K26708780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19327
TWIST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00606
BRD-K05277255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.242
BRD-K98927248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52945
Primary ciliary dyskinesia	ClinVar Gene-Phenotype Associations 2025	1.0	null
BRD-K10398797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.72198
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.176
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01518
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51858914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18287
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.218
BRD-K42126155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85189
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15074
7525_RPS3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.592983
Primary Ciliary Dyskinesia	DisGeNET Gene-Disease Associations	1.0	null
BRD-A81260764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04037
BRD-K70148257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27477
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69291887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10015
GSE182680,GSE182683_7_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26180392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28812
LS411N_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.18548
GSE250560_1_v_0_foxo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15714771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65967
BRD-K70566686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08909
BRD-K01888220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16489
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.473201
BRD-K79768278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25283
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231192
Thymus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vermiform appendix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
NIFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11879
BRD-K37721603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.169
CRCGN017_MCF10A.WT.HP_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06416
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05877335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10449
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11737
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.53082
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.032
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19132
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9400428-7272371.f2.docx-1-MYSM1_MYSM1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
BRD-K49659981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13583
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.753898
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29959
6493_PNO1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.52248
Dendritic knob	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.644
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04535
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03905
8462_SSX2IP_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.534893
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58008
CRCGN016_MCF10A.TP53.M_24H:C13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4724
BRD-K39592958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87031
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Coughing	DisGeNET Gene-Phenotype Associations	1.0	null
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GRB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16397
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.084
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10427
BRD-K15343038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35659
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32226
Primary ciliary dyskinesia 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.402
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
RESF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37882
BRD-K82115725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00728
Paraflagellar rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
BRD-K07385991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09698
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
BRD-K26291134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62604
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7944
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Vertebra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.326
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5441
RPAP3/R2TP/prefoldin-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
GSE124471,GSE124488_1_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124410_3_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6699
BRD-K69671285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14932
CRCGN017_MCF10A.WT.HP_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31389
BRD-A31576716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1971
BRD-K47883435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58689
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4981
BRD-A39506880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67434
BRD-K84178323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06627
BRD-K31994521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27022
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
CALB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610897
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle assembly	GO Biological Process Annotations 2023	1.0	null
CRCGN015_HEPG2_48H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29326
BRD-K79065821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3635
BRD-K04143779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46797
BRD-K62288678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01889
Primary ciliary dyskinesia 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.825
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6781
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7527_RPS5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.517774
BRD-K21910317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83614
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.206
BRD-K89660028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28061
BRD-K87742870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34217
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_7_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
NME2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00706357
6963_PWP2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.501378
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IMCD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
BRD-K09960817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12691
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4909989-ncomms11840-s2.xlsx-up-regulate-The_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_regulated_genes_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114992,GSE114993_4_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97731768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20016
BRD-K20288742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31448
BRD-K88494268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4777
BRD-K02691653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08757
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0267
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2359
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K08966355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88943
BRD-K47754225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02841
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15548
Recurrent Respiratory Infections	DisGeNET Gene-Phenotype Associations	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
10699_ZNHIT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.500927
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.29375
ajmaline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44679
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K13502206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87497
BRD-K04195898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83393
ABHD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00466711
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42362
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26503698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15395
Outer dynein arm docking complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.534
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206784_3_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	1.0	null
HT-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
VSNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1747
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3761
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15287
6446_PLEKHJ1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.571429
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01802
BRD-K85559506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01367
BRD-K78856515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34362
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K82102352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60872
Ectopic Pregnancy	DisGeNET Gene-Phenotype Associations	1.0	null
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05734090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49664
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5648
CRCGN015_MCF10A.TP53.M_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79402
CTSA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00674594
GSE231829_0_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95459450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11564
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
GSE206516,GSE206518_5_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0415
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45663146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21449
BRD-K23956044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05596
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36958
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
BRD-K27320944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19791
GSE112763,GSE112767_4_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72475
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.737
BRD-K61929684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43609
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.491402
BRD-K51791049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76633
NDUFA13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00637282
BRD-K75637705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25297
BRD-K37431309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02146
BRD-K38189757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84574
Spastic quadriplegic cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.688
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20725
TTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2516
Ciliary Dyskinesia	DisGeNET Gene-Disease Associations	1.0	null
GAS7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534006
BA-52-FW03_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.539459
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8888
BRD-K21713052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59666
LSM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01657
Situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.525
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7727
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K68009914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32463
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of microtubule-based movement	GO Biological Process Annotations 2023	1.0	null
BRD-K85440939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25931
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6642
BRD-K77241556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1061
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31285
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Basal body patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.17
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.17422
PMC11655728-12672_2024_1562_MOESM2_ESM.xlsx-Sheet1-Hs_ESC_NANOG_targets_Boyer_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
Muscle myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.582
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8524
BRD-K57262525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00724
GSE151364,GSE151366_1_v_2_taf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
3823_HMG20B_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.511265
BRD-K53192330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67353
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5736
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.70825
BRD-K45328741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65722
9366_TSR2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.570487
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244522
GSE171572_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60760423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45692
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
AC-67-PZ77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211342
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
4271_KANSL2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.537837
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.017
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.539
GSE158834_10_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
B-lymphoblastoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.068
BRD-K99404845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76482
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4305
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dilated Ventricles (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K77399094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62499
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K33016067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10409
GSE220520_5_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38143
BRD-K44131977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07284
GLTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00665856
BRD-K82521114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13196
F2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01995
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33107
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Paranasal sinus disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.781
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.428
KCNS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00382127
GSE99187_1_v_0_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A47798787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5218
Idiopathic scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
BRD-K98239824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32168
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K90047132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76702
BRD-K63462027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10949
BRD-K28919392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54327
Cerebral Ventriculomegaly	DisGeNET Gene-Phenotype Associations	1.0	null
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K43628610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63056
Floor plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.109
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.816
Neural arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
BRD-K04470135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20754
PEAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596582
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Velum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
BRD-K98133478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50876
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8189
CRCGN017_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19565
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1192
BRD-K20942146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56893
Polynesian Bronchiectasis	DisGeNET Gene-Disease Associations	1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
1040_C1ORF131_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.633516
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.802
Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cilium organization	GO Biological Process Annotations 2023	1.0	null
BRD-K42776812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19532
CTNNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00352875
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PNKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.448
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259292
BRD-K93486666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01349
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.727
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394414
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21363
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Otitis media	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
BRD-K85395981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27721
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09143
Ciliated cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE246053_1_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8674
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0845
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kartagener syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.978
PPP1CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00490483
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58217
BRD-K93561942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11018
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K31001397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84023
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2247
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
CRCGN014_HEPG2_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0274
BRD-K05432466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27427
BATF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560299
GSE203308_8_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sclerotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
BRD-K11823863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22793
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22531
TNP-470	DeepCoverMOA Drug Mechanisms of Action	1.0	1.62
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2308
PDHK4	Kinase Library Tyrosine Kinome Atlas	1.0	94.73
BRD-K58323923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44945
PMC9753996-jci-132-160767-s182.xlsx-IRF4_assciated-ABCA7_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42494
BRD-K06284373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55405
BRD-K35964249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84286
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.215
BRD-K71415389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06715
GSE158834_11_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11109217-41420_2024_2017_MOESM3_ESM.xlsx-Fig_4H_TAF2-bound_genes-Tag_dentsity_of_TBP_ChIP-seq_signal_for_TAF2-bound_genes_in_Fig_4H_TBP	Rummagene Transcription Factor Associations 2026	1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4731
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40886
BRD-K76701247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03154
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.504
BRD-K89014570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67035
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01964
4908_MCOLN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.642661
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.275
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17396
BRD-K09144377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23128
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
BRD-K14139166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09984
BCL2A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00500556
BRD-K35860167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19815
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37036
OPRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00700763
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.560264
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68765
GSE198165,GSE198166_7_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.527
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.575106
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31559225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43388
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10232513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34901
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15483
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75961
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.358
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
9839_WDR74_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.524503
BRD-K11389666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41125
GSE114992,GSE114993_0_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12191
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of microtubule-based movement	GO Biological Process Annotations 2025	1.0	null
BRD-K65423474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0352
10792_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.505812
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.419
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56429
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
BRD-K18573205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86006
Thoracic spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29069
BRD-K53127431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02187
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07549
Communicating hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.26116
GSE201309_5_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05575
Primary ciliary dyskinesia 19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
4898_MCM2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.503301
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
FAM171A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33867
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.516842
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
BRD-K12524155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41071
GSE133516_5_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K11168234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28192
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
B-lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.068
Atelectasis	DisGeNET Gene-Phenotype Associations	1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8208823-mmc2.xlsx-CDX2-KO_mesenchymal_DEG-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7312_RIOK2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.507296
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.713746
BRD-K48213854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21859
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4894
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98145661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63337
Clubbed Fingers	DisGeNET Gene-Disease Associations	1.0	null
BRD-K99122228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01527
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.76674
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.76985
1941_CTPS1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.58801
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62554
BRD-K19039329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0257
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.116
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.573
GSTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3831
BRD-K35953312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51705
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AHR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00406115
THNSL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00535409
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294717
BRD-K47498351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53915
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03953354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79543
BRD-A20256229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52231
CEP131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08337
2111_DDX21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.57627
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.833
8826_TEX10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.512544
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.98228
BRD-K15128331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05068
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.99
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.29
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3715
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8065
BRD-K54285478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28474
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03036
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48459037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54513
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17854062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10252
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
BRD-K12955049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18882
BRD-K84688359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78003
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K72694472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17912
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23083
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3458
Rhinitis	DisGeNET Gene-Disease Associations	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37636
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
thoracico-abdominal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0546
BRD-K61517058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65465
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.18
BRD-K22651517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36188
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37608
BRD-K90230495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05596
Renal medulla cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.08
10184_ZNF174_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.522499
BRD-K27525139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31223
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18117162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28708
GSE90754_0_v_1_foxo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.068
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.50853
Tail fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
GSE151782_4_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08107521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34951
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.096
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	1.0	null
Immotile Cilia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52441396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72329
Sinusitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
BRD-K58333451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3297
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2626
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
PMC7934853-jciinsight-6-141851-s210.xlsx-Beta3-Unnamed_0_BHLHE22	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49745710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37156
BRD-K46599443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06742
CRCGN015_MCF10A_48H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0896
Recurrent Sinusitis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K15160749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98494
PMC12211054-spectrum.00100-25-s0002.pdf-76-CENPB_CENPB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23598860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70219
BRD-K47572485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32086
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary ciliary dyskinesia 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.895
BRD-K12517207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67477
BRD-K15943105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07715
BRD-K63937112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59993
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
BRD-K88977610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.116
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary ciliary dyskinesia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30685
BRD-K90111788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78289
Congenital Pectus Excavatum	DisGeNET Gene-Disease Associations	1.0	null
CLK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00621885
BRD-K57075511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73605
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19304
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEKHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41814
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.25
BRD-K64418159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37188
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K06619604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84545
BRD-K80495774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10038
BRD-K95334975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30619
BRD-K61287439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60176
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
IFNA10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00423169
BRD-K30772101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71031
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.06719
BRD-K40252598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16145
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0055
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Primary ciliary dyskinesia 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
BRD-K60456515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00328
Pelvic fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0623
2129_DDX54_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.632854
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87071
ITSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28759
BRD-K88812688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22765
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.527766
BRD-K24640918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02342
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TIFAB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520409
BRD-K77119472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84617
Nasal Polyps	DisGeNET Gene-Disease Associations	1.0	null
BRD-K29086754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12812
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77958314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00601
GSE86507,GSE86509_7_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95543908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28423
BRD-K97798118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98103
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32065
BRD-K90313630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93426
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bronchial mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
BRD-K75331656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19209
Bronchitis, Chronic	DisGeNET Gene-Disease Associations	1.0	null
SCN4B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00453277
BRD-K06418332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00808
EE-04-QG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229874
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448563
BRD-K20525312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82064
BRD-K23333192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98861
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222632
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215234
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84755
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03542527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29915
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4905481-oncotarget-07-11397-s003.xlsx-Pinin_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Impaired Nasal Mucociliary Clearance	DisGeNET Gene-Phenotype Associations	1.0	null
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.558
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15953
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Delayed Speech And Language Development	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K31801624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88598
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9175
EB-07-JB09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23951
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74112
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212931
PMC7431913-Table_1.xls-Sheet1-TablesS1_Gene_clusters_highly_co-expressed_with_MNX1_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A68323834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08329
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:E18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66417
7505_RPS16_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.507894
regulation of cilium movement	GO Biological Process Annotations 2025	1.0	null
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13294
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:B16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24183
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K96969336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88063
Thorax	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09336
MCTP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00479252
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K70969650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28994
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02551
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7094
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12750296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31784
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8206
Type II protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.013
PFKFB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00676441
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_5_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0062
7206_RCL1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.517635
8156_SMC2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.516842
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TTBK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00532292
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.422
Ciliopathies	WikiPathways Pathways 2024	1.0	null
BRD-K95877349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5699
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69613314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03914
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14568
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8173714-NIHMS1678410-supplement-Supplementary_Table_2.xls-OfficialIPEXsig-Supplementary_Table_2_-_IPEX_signature_genes_with_their_average_IPEX_HD_fold_change_in_Tregs_and_Tconvs_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64492
BRD-K10416099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71261
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15365
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35427
KDM4C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00456798
5462_NAPA_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.568331
Trunk	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K02362691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41463
PMC11479675-NIHMS2019542-supplement-5.xlsx-B_HIF1A_score_vs_chr21-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40610042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62339
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53802078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10459
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359238
Primary ciliary dyskinesia 38	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.609
BRD-K16888026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48954
ZNF98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16971
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21386
BRD-K82107433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10936
BRD-K73001304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05523
CHRM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620318
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K71876816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03192
BRD-K90103008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60369
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.822886
SYM-2206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66076
BRD-K29144638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13035
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.38294
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.449
BRD-K79855662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6324
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10284009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07346
Halitosis	DisGeNET Gene-Phenotype Associations	1.0	null
MCCC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583339
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
C17orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0176
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2115
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
3369_GINS1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.50235
BRD-K62718031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43386
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.663833
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K99214816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62365
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.744703
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
5548_NDUFAF5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.51095
BRD-K98156994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20424
BRD-K90874005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20237
BRD-K09112411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33226
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27041
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.76774
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00991
CRCGN016_MCF10A.WT.HP_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33247
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ciliary cap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.076
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
amorolfine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36565
BRD-K78668110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25807
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5868
ELK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520725
RCHACV_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.28611
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33734
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.733
BRD-K56592061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32747
BATF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540618
BRD-K98225007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.80082
Spastic cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Vertebral endplate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260943
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14195
BRD-K85200795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08668
5365_MYBBP1A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.622126
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.23742
BRD-K79222179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19498
GSE114992,GSE114993_9_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K62007935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75316
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08929
BRD-K28848179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35287
GSE220520_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76193544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99779
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9028
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68965
HSD11B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584834
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K18519876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32472
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203969
BRD-K39978929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01721
4499_LAMB1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.517411
BRD-K29392777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19997
JB-89-SI60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225579
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
5933_OGT_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.785221
PTGDR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571558
BRD-K48436333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32622
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77214724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1578
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103372_0_v_3_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78642007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43496
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
7169_RBM28_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.609501
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10436
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K83832060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5935
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
7657_SARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.508393
10523_CBLL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.506657
7515_RPS26_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.619173
BRD-K97242998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24132
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
BRD-K52863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10207
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19725
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11659
MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K72452130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06869
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.499935
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-Unnamed_16_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68450812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68603
F11R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00716308
BRD-K15928912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3351
GSE148692,GSE148695_5_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.54645
Hydrocephalus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K43674766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20025
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5606
BRD-K04544693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18529
PMC10985171-Table_1.xlsx-Table_S3-Table_S3_IPF_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.22661
BRD-K47886441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13155
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07278815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67417
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.05003
KCNQ4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00464785
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26259
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11511
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07485506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4543
Asthma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K27049948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12577
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
TPP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642356
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10532
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52665916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26291
BRD-K91202220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1792
Syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
BRD-K14442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55148
BRD-A77181042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17578
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ASGR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580032
BRD-K50599016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52023
CRCGN016_MCF10A.WT.HP_24H:C05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43451
BRD-K58863194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02669
BRD-K83135157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03893
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC27A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00470642
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6575
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE49929,GSE49931_1_v_0_irf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253414
GTF3C2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00372711
PSMG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0050253
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.442
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200968
BRD-K07501326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29712
BRD-K08416835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7099
BRD-K98301999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13599
BRD-K57688676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68917
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bronchiectasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.09
Primary ciliary dyskinesia 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.246
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.14448
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.467514
CRCGN016_MCF10A.TP53.M_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11361
GSE96991,GSE97117_5_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K85996308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8521
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
e2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
Tachypnea	DisGeNET Gene-Phenotype Associations	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.455
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73809982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11705
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87815532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02913
BRD-K08416880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60977
3086_FIP1L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.58133
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11639743-mmc2.xlsx-LIN28B-gene_name_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97732674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13445
PMC12244016-jcav16p2800s1.pdf-2-CDC5L_CDC5L	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bronchiectasis	DisGeNET Gene-Disease Associations	1.0	null
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K78755361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1853
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42369
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.743
BRD-K02688026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09891
BRD-K44287054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10203
GSE86021_1_v_2_crenolanib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
BRD-K04498687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04297
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
HINT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573431
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Asthenozoospermia	DisGeNET Gene-Disease Associations	1.0	null
GSE215086_4_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K90060707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08911
BRD-K05350978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28452
BRD-K70565285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29103
BRD-K48912618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96054
TESK1	Kinase Library Tyrosine Kinome Atlas	1.0	96.78
CRCGN015_MCF10A.TP53.M_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05595
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dextrocardia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN013_HEPG2_24H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54603
BRD-A35931254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41571
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77345736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87423
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.413
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7375
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.22
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.8298
WWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00837
Chronic Otitis Media	DisGeNET Gene-Disease Associations	1.0	null
Congenital Absence Of Spleen	DisGeNET Gene-Disease Associations	1.0	null
LGALS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00969234
2545_EIF3B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.735748
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7771094-12920_2020_832_MOESM5_ESM.txt--ATF2_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
7507_RPS18_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.560906
BRD-K03376048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67684
BRD-K47098496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22102
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01215
BRD-K96320811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03265
BRD-K48145537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09469
BRD-K46014233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45427
NT5DC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57108
BRD-K78500251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50115
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pineal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52088
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
Chronic Sinusitis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K44133102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84313
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11237
SW1783_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	6.4542
BRD-K52379519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84026
ZNF282	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10335
GSE151782_2_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K11979048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24215
BRD-K28339544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5221
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
BRD-K34498495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27911
BRD-K95023134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12573
DD-74-PJ26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200716
BRD-K21232462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26115
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
BRD-K26351062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10563
Anomalous left coronary artery from the pulmonary artery	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Embryonic axis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAN2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15857
7491_RPP30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.524126
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8189
BRD-K46445956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47761
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0929
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34501
7509_RPS19_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.55744
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9106
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.703888
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11631946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18563
MKK6	Kinase Library Tyrosine Kinome Atlas	1.0	95.56
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K07437885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88655
SLC5A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53966
Ciliopathy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE157296,GSE157298_4_v_5_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Oviduct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.596
PMC7338542-41389_2020_247_MOESM5_ESM.xlsx-BRN2_2_of_3_UP_48_h-Symbol_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
859_BMS1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525838
BRD-K14671528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25806
BRD-K99609051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6548
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9122
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.246
NPAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4331
MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K83139520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56839
BRD-K51335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69378
HOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4231
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4092
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.84795
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8438
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
BRD-K99038919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05312
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.05977
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
9210_TPP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.522379
BRD-K16570418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10752
K562_Lomustine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149825
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
nucleus	GO Cellular Component Annotations 2025	1.0	null
BRD-K78643409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83157
BRD-K46994278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68841
PMC3377115-emmm0003-0726-SD7.xls-ESR1_Positive_module-SYMBOL_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4523
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223540_0_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A67508925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3781
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05737
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10153265-media-3.xlsx-BENPORATH_NANOG_TARGETS_v2023_1-STANDARD_NAME_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Infertility	DisGeNET Gene-Phenotype Associations	1.0	null
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6587
Absent Outer Dynein Arms	DisGeNET Gene-Phenotype Associations	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23637241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45899
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K82187446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40002
BRD-K95900761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2393
BRD-K48052543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73026
Joubert syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Collecting duct cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
BRD-K15833017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08208
BRD-K74705119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21281
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
BRD-K90475322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05038
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29338
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
BRD-K74302837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05217
GSE221955_3_v_2_igfbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92849826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43231
BRD-K74150320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4533
BRD-K78837609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50613
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.352
CRCGN017_MCF10A.TP53.M_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02402
BRD-K76318449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04429
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.183
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250448
MYCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15568
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
BRD-K22405104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21769
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K58140298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16497
GSE158834_11_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05169
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1405
Patau syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90144
FB-67-PL18_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236976
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.473892
BRD-K09203354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20735
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349536
BRD-K79517375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32143
NOP56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01203
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00381
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9314667-Table_1.xlsx-Regulons-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10617
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259044
BRD-K31437957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67602
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7727
Situs Inversus Totalis	DisGeNET Gene-Disease Associations	1.0	null