association	dataset	threshold value	standardized value
PET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
ABHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17397
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.261
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84468
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00068
Digitoxin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0307326
K562_Entinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130877
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38853
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75027
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70347
Tubulin inhibitor 6_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0286583
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.103
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05939
AHCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97664
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78478
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
MTIF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28026
Hexylresorcinol_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0319061
K562_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014681
ASB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43285
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53727
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12128
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.19453
Alopecia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.973
Cognitive decline rate in late mild cognitive impairment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.609691
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36794
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4152
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30347
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1729
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19889
Doxorubicin (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0164828
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43208
Rucaparib (phosphate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0133533
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96818
ZNF296	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63157
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55832
HECA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26637
Male-pattern baldness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5106
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55384
Ornidazole_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0177626
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45626
Uridine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0130858
Baicalin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0153864
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.438
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7305
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51244
Fenofibrate_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0186543
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39921
ZBTB7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13862
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10154
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37892
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68749
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47017
Proglumide_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.046925
K562_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182244
MCF7_Panobinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00710922
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43571
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40173
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98231
Rovs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16347
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.991
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF331	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86301
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7265
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4488
LY-2584702 (tosylate salt)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0427633
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2977
FMNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1481
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45431
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58838
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
4EGI-1_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0353487
XRK3F2_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0601663
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07083
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51761
Bendamustine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0359023
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9412
Binimetinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0582756
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5993
MEPCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44463
Bimiralisib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0356732
Filgotinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0275988
NECTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15783
Bortezomib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0229728
TNKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53593
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03863
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
K562_Quisinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0372924
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14907
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64174
Pioglitazone_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0144916
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90048
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18663
ZNF593	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84645
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81543
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80721
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9103
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68293
GPSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39485
GPATCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23139
KIF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96801
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Tirabrutinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0258617
DCHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45654
K562_Nilotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0114261
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1361
SPRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90627
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.3907
Vinblastine (sulfate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0279599
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71697
Goserelin (acetate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0471013
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09696
AIFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54051
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
ITGA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3538
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90705
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6556
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Obesity-related traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HLA-B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5514
Adenine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0248799
Abiraterone acetate_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.026787
K562_Altretamine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146647
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Rigosertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146035
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09267
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BE(2)-M17 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95001
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28399
CGRRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20534
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42933
Weyers acrofacial dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
PRRC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60985
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
SBI-0640756_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0194584
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1221
Altretamine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.034959
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.6906
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45539
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28552
GSE143643,GSE143644_1_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MATN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7002
CCNB1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32531
COX8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32703
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744
ZNF48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73525
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22616
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5464
K562_Givinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0353846
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cilostazol_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0716456
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64832
ITGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62082
WWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89614
KDELR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61001
Fusidic acid_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0344346
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
Ribociclib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0199097
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE218451_2_v_0_txnip_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP5PB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82158
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02196
ZNF398	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02768
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.9118
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33742
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8423
OTS514_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0580645
MCF7_Quisinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00940638
ZUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
HSPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48875
ASCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66053
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75636
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MGST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5133
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3545
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54705
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08697
Ataluren_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0161693
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95901
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
Pemetrexed_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0268026
RAB6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93003
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.991
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.255
Valdecoxib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0663681
Investment cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73792
K562_Selisistat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161497
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4855
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31552
DLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7622
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
Response to cognitive-behavioural therapy in major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
TCEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71737
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40688
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07963
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77648
c-Kit-IN-1_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0389945
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1803
LPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36642
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47498
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
K562_Andarine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015756
RQC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29368
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29124
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
SELENOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71166
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59099
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26403
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23619
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
C1orf35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33945
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31316
PDIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78105
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05634
ACBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00683
Situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
Retinal perforation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4144
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98175
Bestatin (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0380503
SPATS2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29273
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Azithromycin (hydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0453045
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70557
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17161
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.316
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84988
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10075
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
K562_Belinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0474509
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29884
Infigratinib_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00537355
RFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72842
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
Thymopentin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0591512
UNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3797
ATG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.443
Brain_CT2_Mmb 328	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
IRGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5634
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HERPUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30907
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88274
K562_Dacinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0260335
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3822
Anastrozole_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0329163
Sivelestat (sodium tetrahydrate)_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0117191
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49538
TMEM51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02219
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97339
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50175
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4377
ZNF280D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94979
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CDC42SE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33897
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41114
RNF187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70543
Darolutamide_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0259633
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93359
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47187
PSENEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42145
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.514
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68769
Thymopentin_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0197381
K562_Tofacitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141036
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04603
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7351
ZNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90763
Roxadustat_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0151675
HNRNPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84097
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68257
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
GOLPH3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09263
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF275	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
Idoxuridine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0668637
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4874
C2orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9282
K562_JNJ-26854165_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171026
FAAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4165
Hair disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.973
CDK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79561
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54211
Opioid overdose severity score	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22488
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
K562_Givinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174254
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72717
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7913
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4643
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63828
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87887
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2961
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52852
FAM104A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47915
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43531
TMEM158	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01151
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Outer dynein arm docking complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.01
Everolimus_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0259011
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3587
Imiquimod (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.033182
HCC515	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35324
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8752
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
Triclosan_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0170388
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31037
MTHFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15163
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.421
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2969
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53069
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86019
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81232
NoRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
AMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18516
SLFN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16626
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
Ivabradine (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0471336
GPATCH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32921
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81742
K562_M344_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183581
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14468
Fumaric acid_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0138924
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17335
Adenosine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0744271
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72068
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59942
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76513
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37949
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80623
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51246
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8558
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75649
Celecoxib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0135293
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Minodronic acid_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0256276
FRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12802
Fenofibrate_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0127851
UBE2Q1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49891
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.21057
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4482
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8207
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51311
MCF7_AR-42_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00753888
MCF7_Quisinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00880433
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66596
MCM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05929
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9108
PER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38375
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80087
ELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85758
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21075
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79613
XRK3F2_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0195036
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3056
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43092
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3192
GSE166914_1_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HI-TOPK-032_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0255371
KCTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93172
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Centriolar satellite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22791
MCF7_Trichostatin A_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00983144
Archenteron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.677
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
Sperm individualization complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.925
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77876
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22831
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98841
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97147
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.138
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4316
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22295
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93358
K562_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157847
ZNFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19589
ATMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79261
K562_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017606
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.991
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92459
CSDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95695
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76864
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90108
Oxaliplatin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0268388
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26441
Sinomenine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.025425
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0686
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ALKBH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34428
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70784
ENDOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42203
HNRNPCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8028
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
Cepharanthine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0545028
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3112
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42096
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3899
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4978
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03538
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59989
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5384
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55757
MCF7_Givinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00924283
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67315
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32608
TMEM101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34565
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40428
CP21R7_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0130573
NEK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14535
Posaconazole_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0302831
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Infigratinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0258389
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PELI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99235
Indacaterol (maleate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0576048
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56273
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67319
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0558
Fluvoxamine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0223331
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
MT-ATP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31003
SNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27103
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7064
Macitentan_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0323706
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29155
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04624
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MCF7_Quisinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0108113
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4043
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17038
PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17918
Carbidopa (monohydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0369954
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83614
K562_2-Methoxyestradiol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177827
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9472
SNPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5406
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.097
RASGRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91374
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89344
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82082
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.755
B4GALT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60826
PH-797804_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0246564
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.62223
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2393
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Tie2 kinase inhibitor_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197499
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10008
SLC35A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49488
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81535
MBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82097
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19146
Panobinostat_SW 900	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0188184
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
Plicamycin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0250643
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rifaximin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0312698
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.06318
Phenytoin (sodium)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0163306
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
K562_Resminostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0325514
PMC5794192-ppat.1006868.s001.xlsx-S1B_Table-S1B_Table_Differentially_expressed_genes_between_IRF8-sg2_and_NC_cell_lines_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1591
Trifluridine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0419302
INTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15183
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1051
Ponatinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0694636
NDRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53593
ANGEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92318
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76932
COMMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87341
MCF7_CUDC-907_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00935218
Nanophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89823
Fedratinib (hydrochloride hydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0337578
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86427
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84805
PIH1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88647
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32347
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90527
PSME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86704
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tolmetin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.021688
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58366
K562_Alisertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180325
K562_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154769
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06378
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26004
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4751
LJI308_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0343483
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52906
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27205
Riluzole hydrochloride_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0464714
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63853
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
Bestatin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0289856
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90191
Asciminib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0315072
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86636
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68092
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5933
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1861
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3087
Atrial fibrillation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
Nimesulide_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0152085
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29869
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
GSTK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57886
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Decitabine_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0132695
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49886
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89767_4_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
Entrectinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0302715
GFPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44816
GSE128730_4_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2BK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02322
MICU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81631
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56365
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5889
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
AZD-7648_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0255758
FIBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36174
K562_Temsirolimus_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143853
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.581
WDR76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56202
RHBDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50831
APTO-253_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0164172
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
K562_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146453
GABRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52313
PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40648
Human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Irinotecan (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0420579
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10498
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64317
L-Thyroxine (sodium salt pentahydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0369293
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8119
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92669
Spherical equivalent or myopia (age of diagnosis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96252
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50494
Capivasertib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.064424
CNNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11913
Vitamin K4_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00774294
Tadalafil_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00986905
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3877
Macular thickness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00458
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92574
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54699
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38577
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88186
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66661
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32056
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97667
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78903
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93347
FAM136A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19352
METTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
Pentoxifylline_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0241906
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
K562_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126215
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.538
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ERK5-IN-2_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0110708
ELAVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97737
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5489
HM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86811
TOP1MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7055
Periciliary membrane compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38867
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7446
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97119
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8439
RPS6KB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66294
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91765
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
Nafamostat (mesylate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0349034
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
HOG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.584
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9914
GSE129241_4_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5178
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6277
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
Demeclocycline_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0134492
Ranolazine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0472553
THOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11508
K562_Cimetidine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177865
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
MRPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83691
ETC-206_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0307244
K562_CUDC-101_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0251126
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.991
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32978
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83496
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Menadione_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0188734
MORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65572
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82456
Expressive language disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.615
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21922
PMC12152148-41420_2025_2541_MOESM3_ESM.xlsx-AR-IP-DHT_peak-gene-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75065
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73732
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13192
KDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19603
RBM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.3289
MCF7_Dacinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0102481
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51217
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
Mifepristone_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0275904
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75942
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13271
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13196
Lenalidomide (hemihydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0383572
CCKBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48358
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2968
PTER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75107
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52059
RPP25L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5441
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54109
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
MCF7_Belinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00689265
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84448
NDUFA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5554
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65937
PMC11043400-41467_2024_47805_MOESM4_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7781
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12188
Cytarabine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0295504
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96266
Fulvestrant_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0535174
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12712
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65834
LIPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65556
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60247
Paclitaxel_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0389515
DDX31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36069
Waardenburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
MLH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72213
ascospore-type prospore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.713
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2911
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20489
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23432
JOSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00043
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49923
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.973
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96708
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28202
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0854
Lapatinib ditosylate_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.035668
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.539
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4318
MSANTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0455
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Verapamil_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0474405
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
bf2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
Pentagastrin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0380305
Daptomycin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0617187
SOCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07799
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
MTMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79309
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27088
PMC11376028-13578_2024_1300_MOESM1_ESM.xlsx-CCF_2nd_round-SYMBOL_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82251
SLC39A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11855
Lidocaine (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0150753
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
Microtubule end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.905
MK-8353_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0344776
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
SIX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27605
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3102
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
SEC22C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95628
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6389
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64746
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
KIFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91484
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32417
PRR14L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83665
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RSPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61179
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35582
HOOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78071
Oligodendroglioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
Piroxicam_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0526487
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G6PC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33403
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
CALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15505
K562_Entinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226751
GSE239578_5_v_6_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dorzolamide (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0421724
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70561
GSE146074_1_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49139
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15416
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
IFFO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65541
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67403
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2122
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60822
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62708
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6136
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11862
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48702
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8003
Tazarotene_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0222938
K562_Panobinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0350889
Busulfan_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0331858
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6479
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.367
PPP1R16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64018
Apalutamide_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0300724
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.54025
GSE140284_0_v_1_hhex_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57375
Cyclosporin A_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0229757
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7647
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38169
vincristine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0596286
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85786
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3776
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Appendicular lean mass	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.2
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85943
NKAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47414
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
ZFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7342
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3143
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4619
Roxadustat_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0327741
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3358
Anethole trithione_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0342717
Autosomal dominant intellectual developmental disorder 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.942
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65995
Androgenic alopecia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.973
Doxycycline (monohydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00893874
Hypotrichosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.973
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65239
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3781
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
Auranofin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0472885
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48819
Lopinavir_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0262348
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3942
CYP2A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7242
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13206
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48919
Mitoxantrone (dihydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0550356
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57589
TPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86611
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07647
HA1E	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
GNAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20104
RAB9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
TRIM61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52862
TPMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57224
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.315
SLC35C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00706
ARAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68166
SENP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5584
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59125
PRNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37635
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1814
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4892
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55561
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9709
B3GNT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44969
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.067
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77244
Sulfatinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0459775
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6209
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ameloblastic layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52164
Futibatinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0507269
Gemcitabine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.039946
Belinostat_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0175943
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12693
Benztropine (mesylate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0238503
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
SH2D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45084
Temsirolimus_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0428914
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0519
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bisoprolol (hemifumarate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0331939
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45212
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07234
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91092
K562_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195335
ZNF461	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42581
H2BC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08968
PMC11043400-41467_2024_47805_MOESM4_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15397
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2108
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3873
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Benproperine (phosphate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0106583
TCEA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4955
SNRNP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41306
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr4_80694034_T_C_b38	GTEx eQTL 2025	1.0	6.1552
Lactate (calcium)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.059283
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22705
Bosentan (hydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0487224
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2251
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25618
Neratinib (maleate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0270719
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9363
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017495
K562_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145953
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5318
BATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19286
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5986
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09505
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12061
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41229
Amsacrine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0324867
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47523
Ependymal cell_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
Allantoin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.022244
Almonertinib (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0328408
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.991
Tucidinostat_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0480131
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95052
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Saquinavir_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0289529
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8502
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
Mitoxantrone (dihydrochloride)_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0206431
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78922
Drospirenone_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0184608
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96248
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00749
L-Eflornithine (monohydrochloride)_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0208161
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Chronic kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE207512,GSE207515_1_v_2_acetylcysteine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39916
Rimonabant (Hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0288959
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33069
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1323
ACBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61299
Cloxacillin (sodium)_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.019154
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4894
EWSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77336
ZNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7403
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4728
Norepinephrine (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0182105
Ferulic acid_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0285233
MDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86016
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.978
K562_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0263605
SLC52A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49491
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
Flutamide_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00956567
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53975
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7535
Microtubule plus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.306
Ivermectin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0250826
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05471
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.949
ZNF511	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66951
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40728
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM184A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27959
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
MED25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19443
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_upregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29233
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90697
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74503
Heart conduction disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.622
cone-rod dystrophy 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
Ciliated cell_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
K562_AR-42_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206556
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04409
Oral apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.129
TMED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26743
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CDC42EP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28326
AP1AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92057
JRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72508
IGF2BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94152
Decitabine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0515417
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
Homoharringtonine_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0343859
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30711
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6356
HOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22545
ZNF646	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78416
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60409
TOP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35777
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51489
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7664
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42684
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.24492
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4139
CTDSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39836
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65236
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7315
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18047
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40322
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27857
DDX19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27055
TESMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89093
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74397
SMAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47684
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
Simotinib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0175573
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
Vilanterol_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.081519
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5534
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
K562_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175776
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.934
Finasteride_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0279795
DTP3_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.035281
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96869
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6717
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3062
Pitavastatin (Calcium)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0406334
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
CTSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18214
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27299
9-ING-41_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0470804
FAM53C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1434
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15958
DCUN1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76639
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6868
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54043
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.406
Idarubicin (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0439547
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.3374
K562_Pracinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168707
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66186
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2325
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MK-3903_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0278824
POU4F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62541
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21727
Ataluren_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.026194
DLX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34453
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
HELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53669
PI4KA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26115
Pralsetinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0232131
GET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09568
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01891
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91576
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81017
CLPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58101
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35015
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1947
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.4211
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83371
RASSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54235
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52745
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0853
HIBADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83565
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Delamanid_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0199158
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1228
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1146
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CYP27C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77375
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2819
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52199
K562_AZD1480_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152034
Cataracts	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.15229
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2398
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Captopril_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0661763
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60992
TCFL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68842
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3481
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54526
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1749
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11753
Bimatoprost_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0200297
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.72
Ixazomib citrate_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0192737
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23932
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95653
PEAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0507
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16857
GLRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24258
Econazole_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0426238
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.795
Edoxaban (tosylate monohydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0431246
MCF7_Dacinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00696558
MAFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05193
Entecavir (monohydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0399514
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5287
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22882
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64541
CISD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93094
HTRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.507
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.396
ZDHHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96565
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
CLCN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71111
DBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59702
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8388
Trachea	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21282
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35943
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75304
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
DHX32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31872
Tetracycline (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0473817
K562_Resminostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146696
MSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07834
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96072
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40748
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LAMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21161
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
Fluvoxamine (maleate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0368531
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6855
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3421
Zileuton_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0280615
PMC9314667-Table_1.xlsx-Regulons-IRF1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160558
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3066
palbociclib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0322256
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Irinotecan_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0309019
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
MCOLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1287
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89607
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3517
Quinidine (15% dihydroquinidine)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0190603
RFWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32484
Hesperidin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.017335
K562_YM155_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151256
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
Ciliary rootlet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
CTNNBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69543
SCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6773
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77618
Artesunate_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0305759
PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0256
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90845
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29915
Sinomenine_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.020706
LCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73
POLQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85922
HRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37959
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1915
DNAJC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12683
Prospore membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
Lumateperone (tosylate)_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0187708
Folic acid_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0206589
ZNF875	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08366
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3868
Methotrexate_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0521914
crizotinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0185589
PEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75753
ML264_hTERT-HPNE	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.019507
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1201
Flumatinib (mesylate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0173949
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64395
FAM83E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85374
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83176
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56024
APPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82387
MMADHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86918
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91263
OTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12773
Pioglitazone_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0140943
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
SERBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2196
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53438
PYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02779
Lipoic acid_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0223347
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7161
CPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92287
FES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86586
Intracellular immature spore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24214
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
SBNO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37814
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73641
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08832
Procainamide (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0384169
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
PMC4392212-gutjnl-2013-306620-s9.pdf-12-SETDB1_SETDB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20985
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5956
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.755
Brain_CT2_Mmb 328	HuBMAP ASCT+B Annotations	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0917
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
Atazanavir (sulfate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0182112
Wart	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03144
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Myocardial infarction	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.37
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
K562_Aminoglutethimide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157151
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30243
Acetazolamide_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.053633
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62368
MXRA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80029
Ependymal cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Capmatinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0676035
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
C1QBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92318
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	1.0	null
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87893
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21115
OPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42659
Phenylephrine (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0226854
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74807
MCF7_Panobinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00881394
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1405
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26374
OXSM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
K562_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159236
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40132
DUSP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79056
Sildenafil_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0486529
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14458
H3-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73527
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Aliskiren_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0143402
OGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35072
NDUFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20536
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92592
GALE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50989
Bicalutamide_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0476284
K562_Celecoxib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019153
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21002
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40769
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28079
Canagliflozin_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0460524
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9481
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47843
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22943
RBBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77478
Sivelestat (sodium tetrahydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.030474
Cysteamine (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0432519
CTDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15524
Pimozide_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0277639
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
Coronary artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.37
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2053
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8267
KIAA1191	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27531
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50099
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4031
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
Ciclopirox_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0296569
PMC9973477-2021_280405_vanderZWET_TABLES1_SUPPL.xlsx-NR3C1_meme_1-Gene_Name_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2435
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99882
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57187
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53843
Pexidartinib (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0251326
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114992,GSE114993_4_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pemigatinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0235296
K562_Dacinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0401416
K562_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145022
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PTDSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85252
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE166004_5_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sulfisoxazole_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0325262
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9402
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10861
NG25_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.025365
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27614
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Dimethyl fumarate_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0152031
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3122
K562_Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153436
Glycyrrhizic acid_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0274969
Monocrotaline_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0401321
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61263
DAGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64452
Simotinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0224979
DUS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52379
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.129
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27787
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Tucatinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0279196
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91069
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.6628
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30356
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32364
Ouabain (Octahydrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0197856
Spermatogenic failure 51	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.324
crizotinib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0131602
DCAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58576
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
Tofacitinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0516143
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0823
IFFO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40232
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15069
Dexamethasone_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0363743
olaparib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0217572
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48697
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42932
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71397
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0511
m90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15273
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTPN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23851
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90131
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95626
EME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54334
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89372
Tirabrutinib (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0152728
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6345
PMC7064337-elife-51373-supp2.xlsx-652_genes_up-regulated-List_of_652_genes_up-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
Pentamidine (isethionate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0299791
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Methyl aminolevulinate (hydrochloride)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0236018
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
MCF7_Pracinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00875099
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20511
FHIP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46976
Gefitinib_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0371316
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
Clobetasol propionate_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0267127
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74689
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74122
Tofacitinib (citrate)_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0482952
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23779
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Isocorydine_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0256596
K562_Veliparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135029
CYP51A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5432
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62047
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CP21R7_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0165632
TMEM170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83099
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48712
AHCTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72601
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82319
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.991
CIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75025
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32608
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mebendazole_MIA PaCa-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0225106
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76297
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9176
Kidney failure	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
PBXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02043
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36129
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null