association	dataset	threshold value	standardized value
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30722
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8202
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21101
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7914
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43455
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
SUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43833
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25609
Acrosomal vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC5967331-41467_2018_4384_MOESM4_ESM.xlsx-Sup_data1_with_CCF_txt-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66778
TUBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13382
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10421
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.10364
CDC42EP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04493
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40453
immotile sperm	MGI Mouse Phenotype Associations 2023	1.0	null
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
decreased body size	MGI Mouse Phenotype Associations 2023	1.0	null
chr2_219040977_C_CAT_b38	GTEx eQTL 2025	1.0	1.17064
H3-3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00118
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8261
Waist-Hip Ratio	DisGeNET Gene-Phenotype Associations	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ITGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43173
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76127
ALG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06482
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
PMC8494348-pone.0257161.s002.xlsx-only_OXT_NOT_ext-OXT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.988
DNAJC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97685
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58902
VCAP	DepMap CRISPR Gene Dependency	1.0	5.51762
ABCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2641
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27929
RNA binding	GO Molecular Function Annotations 2023	1.0	null
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7532
LYSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
SKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53702
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9972
CPEB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68448
SETD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10483
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.218
LRRC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52963
kinked sperm flagellum	MGI Mouse Phenotype Associations 2023	1.0	null
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8053
GSE113267_3_v_2_rfx7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7539
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
HOXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18792
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.668
Phelan-McDermid syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
KARPAS422	DepMap CRISPR Gene Dependency	1.0	2.23141
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1722
ITLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.363
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39791
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34989
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98339
MIEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6612
LARP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12734
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43092
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41356
abnormal acrosome assembly	MGI Mouse Phenotype Associations 2023	1.0	null
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02242
LETMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8465
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71931
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.037
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
VKORC1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24792
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
HERPUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30907
SHCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66041
C19orf53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54658
ZDHHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47365
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZMAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71306
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62872
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8276
GSE180185_7_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C1GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36855
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41711
abnormal spermiogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
TAPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29185
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71002
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25429
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63959
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95495
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.264
TPRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47813
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63852
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64407
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTDSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39836
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBC1D17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44925
DNAJB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4087
TRAPPII protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.542
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37348
MME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5214
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53568
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57296
GOLGA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27963
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55404
ZFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7342
ZNF287	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7194
Congenital bilateral absence of vas deferens	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75568
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
NSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
BRI3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59069
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4916
RABIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.194
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16171
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.361
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71699
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72936
CNNM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88842
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04497
ZNF266	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74751
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
RAB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60698
CITED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51309
GSE146074_1_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4324
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38527
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90969
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95087
Kartagener syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
Flagellum attachment zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17353
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69619
COQ8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42339
ZKSCAN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55312
ZDHHC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98873
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85547
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8535
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3967
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76667
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8229
YF-57-HO38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214107
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	2.23316
MAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4132
3M complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.332
SEH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6626
PMC3046820-supp_db10-1270_DB101270SupplementaryData2.xls-Table_2S_Adioose_AA_vs_EA-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Waist circumference adjusted for body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00661
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95118
PMC9886955-41420_2023_1325_MOESM12_ESM.xlsx-H6_14AvsH6_NC-Unnamed_2_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84554
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85117
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
162 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
CGRRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24004
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80589
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01919
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38088
Spermatogenic failure 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.255
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
TPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71709
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TXNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24028
male infertility	MGI Mouse Phenotype Associations 2023	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59648
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28401
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50116
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02665
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85465
JF-79-OI50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.398305
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00126
PSMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3253
UBE2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17068
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98841
BHY	DepMap CRISPR Gene Dependency	1.0	2.02718
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
PMC4060771-170289.f1.pdf-527-FOXA3_FOXA3	Rummagene Transcription Factor Associations 2026	1.0	null
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21296
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25133
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39327
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81045
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39417
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35596
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14386
Subfertility	DisGeNET Gene-Disease Associations	1.0	null
abnormal manchette assembly	MGI Mouse Phenotype Associations 2023	1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0127
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
SNU1079	DepMap CRISPR Gene Dependency	1.0	6.02018
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.218
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05932
SLC18A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45393
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88869
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.33979
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.321
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54938
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35089
RELCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2816
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90445
increased male germ cell apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.753
DNAAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88968
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.217
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01732
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2013
FREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45262
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
SP140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35356
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09184
B4GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1503
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47646
PCGF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87188
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5598
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
TTC9C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25972
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_9_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
FKBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08249
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164494_0_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8759
GSK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40894
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70434
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82446
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61851
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1155
ZSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72208
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41639
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20969
coiled sperm flagellum	MGI Mouse Phenotype Associations 2023	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.50817
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56611
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61382
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72848
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.664
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27565
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5726
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.216
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49616
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1096
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76884
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06079
NR1H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49554
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2546
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07647
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90523
MYF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06452
EMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87629
NSUN5P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12362
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28878
ANTXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21695
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90663
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74395
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07314
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.571
obsessive-compulsive personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.783
PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Unnamed_2_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
asthenozoospermia	MGI Mouse Phenotype Associations 2023	1.0	null
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85741
SPCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26936
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41701
ZBTB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15703
MEF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71949
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45229
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53089
C1orf198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82549
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65078
ZC3H15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31022
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.336
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.152
RAB33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29573
Duodenal ulcer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.336
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.99
TLCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41366
UOK101	DepMap CRISPR Gene Dependency	1.0	2.76219
PDZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8817
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.896
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40012
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58748
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40092
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07706
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08165
GSE62843,GSE64371_2_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.679
RNASEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70563
EN	DepMap CRISPR Gene Dependency	1.0	3.01986
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5624
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62147
Gastroschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.775
PMC3470785-NIHMS377161-supplement-14.pdf-481-ZNF708_ZNF708	Rummagene Transcription Factor Associations 2026	1.0	null
INHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63332
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40915
TBC1D20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04308
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02566
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.228
RUVBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48033
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
D502MG	DepMap CRISPR Gene Dependency	1.0	2.12456
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26258
INA6	DepMap CRISPR Gene Dependency	1.0	2.64684
RSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90887
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72143
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8536
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11744
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30836
Swine testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
DHX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3872
NDFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8045
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.208
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79896
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67303
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.19751
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22194
Microcystic meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
ECHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1269
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
PPWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29381
t63-testes_male_2w	MoTrPAC Rat Endurance Exercise Training	1.0	4.90424
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
FKBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55283
EFM19	DepMap CRISPR Gene Dependency	1.0	2.76786
Skull cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15127
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40379
Olfactory placode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
XRCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31217
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7375
THRAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00074
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96136
H3C12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30292
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71837
C1orf35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33945
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35122
ARL6IP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53387
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Ruijs-Aalfs syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94626
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23656
oligozoospermia	MGI Mouse Phenotype Associations 2023	1.0	null
TMEM209	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1705
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2935
teratozoospermia	MGI Mouse Phenotype Associations 2023	1.0	null
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86726
DYNLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48347
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50295
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34277
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59209
Laryngeal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24286
SLC38A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96081
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63924
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50207
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85793
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7507
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3059
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1221
SMAD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31057
ABCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38951
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16424
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
RAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7047
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.336
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4829
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84584
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65547
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_0_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Male infertility due to acephalic spermatozoa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.252
HOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68515
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36692
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4488
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
DESI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30613
abnormal sperm mitochondrial sheath morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.455
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06862
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83655
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
RUFY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35245
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.407679
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80036
GSE100217_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ENTPD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72628
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12058
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27234
Schizophrenia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2203
DENND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0771
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58478
Animal cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
Skull base cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04153
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41164
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61778
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2898
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96245
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95923
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36633
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.119
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18676
elongated manchette	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF516	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27076
Tonne-Kalscheuer syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
CCNY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02165
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60441
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205853
abnormal seminiferous tubule morphology	MGI Mouse Phenotype Associations 2023	1.0	null
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.894
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01786
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94423
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48315
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38951
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_NOT_Autophagy_NOT_GSE22255_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
ATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51082
NABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51428
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99414
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52293
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57525
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5278
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86531
GSPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22108
RNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47874
CTAGE15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32053
ARHGEF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38866
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45171
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17395
PNKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59046
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84492
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29831
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0143
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1702
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
TPCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99667
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43436
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZXDB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3922
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21253
H1-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33931
abnormal sperm head morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81897
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03883
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
CD164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9396
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77849
MARCHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58135
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33015
H2AC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98913
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.91692
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64395
SH2D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6301
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11155
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
BE-29-HA72_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278854
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20951
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.774
t63-testes_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.46171
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54526
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
PXDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46625
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74116
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47612
ACAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72127
ARL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05259
Pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42462
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.371
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
WARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7417
GSE186287_1_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11643
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53096
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17983
ectopic manchette	MGI Mouse Phenotype Associations 2023	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.9028
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bone carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
SCML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50818
TMEM237	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17734
HOXB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94011
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37854
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9798
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12324
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09775
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28008
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224176
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal sperm flagellum thickness	MGI Mouse Phenotype Associations 2023	1.0	null
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.488
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41441
EML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57782
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69695
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72808
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
abnormal spermatid morphology	MGI Mouse Phenotype Associations 2023	1.0	null
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
LS411N	DepMap CRISPR Gene Dependency	1.0	5.75632
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89636
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70347
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83439
PMC10863267-12864_2024_10083_MOESM1_ESM.pdf-39-FEZF2_FEZF2	Rummagene Transcription Factor Associations 2026	1.0	null
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.614
PRPF38B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62085
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25874
ATP2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55269
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68578
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49751
RAB39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86868
GSE164494_0_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
MAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21148
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HECA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26637
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82081
detached sperm flagellum	MGI Mouse Phenotype Associations 2023	1.0	null
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96072
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46896
SOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31087
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10032
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31526
ZC3H7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4411
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
MCOLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07621
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29082
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal sperm radial spoke morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE246576,GSE246826_0_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7106
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77732
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63417
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57526
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BTBD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55808
PLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18945
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68926
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19911
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6671
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3286
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17242
SMARCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29241
METTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98759
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1967
acrosomal vesicle	GO Cellular Component Annotations 2023	1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
RNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68672
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83518
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33564
KYSE30	DepMap CRISPR Gene Dependency	1.0	5.47188
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1728
SCAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18779
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70663
Sperm connecting piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
HDGFL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45667
AMO1	DepMap CRISPR Gene Dependency	1.0	14.9304
CYP51A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5432
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19089
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39588
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
CLDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18135
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
CREB3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20657
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6393
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MRPS33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRPM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84564
abnormal acrosome morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1523
ELOVL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54013
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.146
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.823
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8183
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
THBS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8946
postnatal growth retardation	MGI Mouse Phenotype Associations 2023	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4801
NMUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31252
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
Ectoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.824
HEXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26687
short sperm flagellum	MGI Mouse Phenotype Associations 2023	1.0	null
Eisosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.665
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
C1orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3962
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05111
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
acrosomal vesicle	GO Cellular Component Annotations 2025	1.0	null
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59797
HUNS1	DepMap CRISPR Gene Dependency	1.0	2.75464
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9009
NCIH526	DepMap CRISPR Gene Dependency	1.0	6.16604
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
ADAMTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61723
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.746
ZBTB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2294
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56899
WM115	DepMap CRISPR Gene Dependency	1.0	4.9508
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.269
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7057
SMARCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33523
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4722
MYRFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0212
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47679
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09307
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6446
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55722
M040416	DepMap CRISPR Gene Dependency	1.0	2.72155
abnormal outer dense fiber morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.46
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09511
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89934
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78559
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63851
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.961
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6408
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34031
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94262
BATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0286
CTTNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69717
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.817
RYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87796
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8558
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49374
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.231
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8761
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.9356
WDR76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56202
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59575
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53959
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80057
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25883
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39658
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23571
MRPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19956
small testis	MGI Mouse Phenotype Associations 2023	1.0	null
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01237
GSE101239_5_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9197
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28035
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
ATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67878
C8orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70249
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70114
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1281
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7185
GSE176305_0_v_1_rotenone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10458
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70368
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82215
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25902
CCDC78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62649
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4651
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4225
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF585A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58656
ATL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41825
AP2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39671
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63618
MKN-45 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12128
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
697	DepMap CRISPR Gene Dependency	1.0	3.80822
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.282
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53727
PHF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20959
SOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13741
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20911
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95837
CTU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25136
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9615
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46382
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3984
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sperm head plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6701
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28358
CHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12452
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29069
absent sperm axonemal central pair	MGI Mouse Phenotype Associations 2023	1.0	null
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.733
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87832
MAGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62064
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17568
Male Infertility	DisGeNET Gene-Phenotype Associations	1.0	null
PPP1R17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30605
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57021
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
Sperm annulus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.811
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13862
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.08
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71114
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.28152
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09969
MAPKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37815
GSE209533_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6004
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11463
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18498
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6501
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75291
TYW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.20929
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75582
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79979
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57156
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
GSE226397_0_v_1_cystine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.114
ELOVL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91424
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52106
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MSTO211H	DepMap CRISPR Gene Dependency	1.0	5.57228
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41909
RRP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58443
THY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26524
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
NIFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2431
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16893
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75304
SPSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07183
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4858
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60822
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3579
Situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.511
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70616
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8887
Sperm fibrous sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.661
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91915
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29259
PMC11055867-41598_2024_60205_MOESM1_ESM.pdf-11-SMAD3_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.741
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
ESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64955
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4826
U2OS	DepMap CRISPR Gene Dependency	1.0	5.63665
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48352
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65725
CBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45109
PMC11933697-41467_2025_58216_MOESM9_ESM.xlsx-SD7_C_R_NS1_Med_ATF3_DEG-symbol_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Sperm mitochondrial sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.907
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.868
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48102
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30268
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83411
NCIH28	DepMap CRISPR Gene Dependency	1.0	5.22104
FKBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01459
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0907
PVR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6928
CD177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3193
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.191
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.30165
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37841
GSE176305_0_v_3_rotenone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69078
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.869
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9477
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63757
CE-00-EK89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.471205
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03443
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22408
sperm flagellum	GO Cellular Component Annotations 2023	1.0	null
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05203
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.087
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84107
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.757
SLC36A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52012
ZNF484	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49019
GSE233112_2_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31791
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.47449
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18321
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08244
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37215
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.7349
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28613
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25098
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
CAPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48688
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98863
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0357
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
NFAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82024
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26925
AKAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7566
PMC11903305-41586_2024_8507_MOESM3_ESM.xlsx-Table_S1_MAF-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94119
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.336
Sperm flagellum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.952
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
absent acrosome	MGI Mouse Phenotype Associations 2023	1.0	null
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82587
PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94866
ST3GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6931
abnormal sperm axoneme morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26284
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
ZNF728	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44209
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC2A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95496
KCNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4637
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58959
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24896
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33828
5g3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
ORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47841
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17821
GSE241701_4_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
CD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49058
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15091
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
Ependymal cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5093
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67549
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.555
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6569
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2565
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.369
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1274
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35034
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SFXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99654
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
HCFC1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14245
EDNRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1381
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99636
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.7962
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31711
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93637
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00574
GSE157894_2_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38145
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05964
TBC1D14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8319
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61864
DDAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.388
decreased testis weight	MGI Mouse Phenotype Associations 2023	1.0	null
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47973
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1754
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37387
ZDHHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5661
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54736
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
9+2 motile cilium	GO Cellular Component Annotations 2025	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2251
PHF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56336
TNRC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22434
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19229
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81553
CCDC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90336
ICC3	DepMap CRISPR Gene Dependency	1.0	3.25927
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.575506
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41461
MICALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59955
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34728
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01591
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47677
KCTD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47706
abnormal sperm connecting piece morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Nucleoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.588
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03263
PABPC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42242
PMC9263655-mmc3.xlsx-ZNF436-AS1-Prediction_catRAPID_ZNF436	Rummagene Transcription Factor Associations 2026	1.0	null
GSTA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3277
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94223
SNAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20115
ALDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85758
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
HOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4231
9+2 motile cilium	GO Cellular Component Annotations 2023	1.0	null
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39137
APLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04737
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
C10	DepMap CRISPR Gene Dependency	1.0	2.87855
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.164
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1269
abnormal sperm flagellum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
MCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72579
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42631
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33965
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
GOLPH3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4197
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09343
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2546
TUHR4TKB	DepMap CRISPR Gene Dependency	1.0	3.12075
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25459
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14675
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0858
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94352
CIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32206
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66846
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91231
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58781
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15752
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2655
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0715
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20985
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20379
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
WDR91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.56371
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Deuterosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
TC205	DepMap CRISPR Gene Dependency	1.0	3.80221
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31316
SLC43A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03362
sperm flagellum	GO Cellular Component Annotations 2025	1.0	null
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NAGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80091
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.609
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47671
GSE210885_0_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30439
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23343
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CARMIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51432
MAFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05193
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66235
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16462
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05634
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
Body Height	DisGeNET Gene-Phenotype Associations	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.56159
SEPTIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90206
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6517
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36165
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC15	DepMap CRISPR Gene Dependency	1.0	7.66254
PMC10248509-Data_Sheet_5.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9898
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83906
detached acrosome	MGI Mouse Phenotype Associations 2023	1.0	null
METTL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3098
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86776
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36761
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
RBPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73445
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95907
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23691
RHOD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78096
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67085
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71567
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC11176070-41588_2024_1754_MOESM4_ESM.xlsx-Supplementary_Table_13_-_AR_Tar-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80623
SLR26	DepMap CRISPR Gene Dependency	1.0	2.15966
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49463
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21376
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49196
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55736
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99052
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33791
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73625
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79533
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.06
SMZ1	DepMap CRISPR Gene Dependency	1.0	3.63902
C19orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22936
CL11	DepMap CRISPR Gene Dependency	1.0	3.38602
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07114
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69619
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56761
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68605
OPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37821
COL9A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57669
S1PR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66414
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77327
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HMGCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34028
TCEAL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23092
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65236
Sperm midpiece	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
B4GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83391
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48836
SC-76-YF40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266929
MRPS18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28162
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19408
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61871
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21604
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27732
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92837
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88534
Skull base meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10087
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
DAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19516
Peptic ulcer disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.336
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41718
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55306
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90259
HOXC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43858
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
SPATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99387
496100490_HIP_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24804
PNPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94019
HELZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55233
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_8_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15808
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01652
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04654
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.159
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7651
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1704
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16078
RASL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86942
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0633
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06417
PE-82-OK78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268721
SPATA5L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.569
EIF4G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13021
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45606
RASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65596
EVSAT	DepMap CRISPR Gene Dependency	1.0	5.62947
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.19706
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54914
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.999
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82319
PMC4082364-supp_ddu111_ddu111supp_table9.xls-Tabelle1-Table_S9_MSC_WT1Wilms3_-_top_100_genes_down-regulated_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
FBXL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21048
TRIAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53637
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09207
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10255
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5429
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
absent sperm flagellum	MGI Mouse Phenotype Associations 2023	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9812
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03078
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46496
PMC10806738-mmc2.xlsx-Table_S1-Table_S1_Table_of_significantly_adjusted_p-valued_0_05_up-regulated_genes_log2FC_1_in_MAX-R60Q_transfected_HEK293_cells_relative_to_MAX-WT_transfected_cells_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47183
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79558
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73377
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
gamma-tubulin small complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
MYOZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59066
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8302
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80087
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68694
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48982
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
t52-hippocampus_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.4421
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6754
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50366
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2551
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
MRPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98974
TC32	DepMap CRISPR Gene Dependency	1.0	5.75188
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1918
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5072
GSE183327,GSE183328_3_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73951
9+2 motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7861
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19146
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98274
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130401_6_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3718
SLC29A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94863
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.2963
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19412
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99858
USP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69663
RSPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61179
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41042
Subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625